| Angel Acevedo | 17 | P | 6-1 | 205 | R | R | 1998-09-19 | Calabozo,VZ | AA | | 2016-2022 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Kelvin Alarcon | 17 | 3B-1B | 6-1 | 155 | B | R | 1999-03-06 | Villa de Cura,VZ | AAA | | 2016-2022 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Brandon Alger | 24 | P | 6-3 | 190 | L | L | 1991-07-04 | Fort Wayne,IN | AA | | 2012-2016 | 2012- 26- 795-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Austin Allen | 22 | C | 6-1 | 219 | L | R | 1994-01-16 | St. Louis,MO | MLB | 2019-2022 | 2013-2025 | 2015- 4- 117-SDN | San Antonio Missions (AA) ... Fort Wayne TinCaps (A) |
| Logan Allen | 19 | P | 6-3 | 200 | R | L | 1997-05-23 | West Palm Beach,FL | MLB | 2019-2024 | 2015-2024 | 2015- 8- 231-BOS | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Alexi Amarista | 27 | CF | 5-6 | 160 | L | R | 1989-04-06 | Barcelona,VZ | MLB | 2011-2017 | 2008-2025 | 2007- UDFA -ANA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Arizona Padres (Rk) |
| Luis Anguizola | 22 | C | 5-11 | 210 | R | R | 1994-02-27 | David,PN | A | | 2016-2017 | 2016- 25- 744-SDN | Arizona Padres (Rk) |
| Bryant Aragon | 18 | C | 6-2 | 160 | L | R | 1998-04-10 | Ciudad Obregon,MX | AAA | | 2015-2021 | 2014- UDFA -SDN | Dominican Padres (Rk) ... Arizona Padres (Rk) |
| Oswaldo Arcia | 25 | LF-RF | 6-0 | 225 | L | R | 1991-05-09 | Anaco,VZ | MLB | 2013-2016 | 2009-2025 | 2007- UDFA -MIN | San Diego Padres (MLB) |
| Juan Arias | 21 | P | 6-2 | 175 | R | R | 1995-05-06 | Bani,DR | Rk | | 2015-2016 | 2012- UDFA -WAS | Arizona Padres (Rk) |
| Martires Arias | 25 | P | 6-10 | 215 | R | R | 1990-11-10 | Bani,DR | A+ | | 2010-2016 | 2008- UDFA -NYN | Lake Elsinore Storm (A+) |
| Yeison Asencio | 26 | RF-OF | 6-1 | 225 | R | R | 1989-11-14 | Santo Domingo,DR | AAA | | 2010-2024 | 2009- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Elliot Ashbeck | 22 | P | 6-3 | 220 | L | R | 1993-11-16 | Marshfield,WI | AA | | 2013-2019 | 2015- 16- 477-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Carlos Asuaje | 24 | 2B-SS | 5-8 | 160 | L | R | 1991-11-02 | Barquisimeto,VZ | MLB | 2016-2018 | 2013-2021 | 2013- 11- 323-BOS | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Luis Asuncion | 19 | OF | 6-4 | 205 | R | R | 1997-02-27 | Santo Domingo Centro,DR | A- | | 2014-2019 | 2013- UDFA -SDN | Tri-City Dust Devils (A-) |
| Lake Bachar | 21 | P | 6-2 | 219 | R | R | 1995-06-03 | Winfield,IL | MLB | 2024-2025 | 2015-2025 | 2016- 5- 144-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Arizona Padres (Rk) |
| Chris Baker | 21 | IF | 6-1 | 180 | R | R | 1994-11-29 | Redwood City,CA | AA | | 2014-2019 | 2016- 17- 504-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Kyle Bartsch | 25 | P | 5-11 | 200 | L | L | 1991-03-10 | Hurst,TX | AA | | 2010-2016 | 2013- 7- 204-KCA | San Antonio Missions (AA) |
| Buddy Baumann | 28 | P | 5-11 | 198 | L | L | 1987-12-09 | Chicago,IL | MLB | 2016-2018 | 2007-2022 | 2009- 7- 212-KCA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| David Bednar | 21 | P | 6-1 | 250 | L | R | 1994-10-10 | Pittsburgh,PA | MLB | 2019-2025 | 2014-2025 | 2016- 35-1044-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Carlos Belen | 20 | P | 6-1 | 250 | R | R | 1996-02-28 | Santo Domingo,DR | AAA | | 2013-2025 | 2012- UDFA -SDN | Fort Wayne TinCaps (A) |
| Edwuin Bencomo | 17 | P | 6-2 | 205 | R | R | 1999-04-14 | Rio Chico,VZ | AA | | 2016-2023 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Ramon Benjamin | 29 | P | 6-1 | 195 | R | L | 1987-06-14 | San Jose de los Llanos,DR | AA | | 2007-2016 | 2006- UDFA -MIA | San Antonio Missions (AA) |
| Tim Berry | 25 | P | 6-3 | 180 | L | L | 1991-03-18 | San Diego,CA | AAA | | 2010-2018 | 2009- 50-1496-BAL | San Antonio Missions (AA) ... Tri-City Dust Devils (A-) |
| Christian Bethancourt | 24 | C-1B | 6-3 | 205 | R | R | 1991-09-02 | Panama City,PN | MLB | 2013-2024 | 2009-2025 | 2008- UDFA -ATL | San Diego Padres (MLB) |
| Felipe Blanco | 22 | SS | 6-1 | 175 | R | R | 1993-12-09 | Valverde,DR | AAA | | 2011-2017 | 2010- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Jabari Blash | 26 | OF | 6-5 | 235 | R | R | 1989-07-04 | St. Thomas,VG | MLB | 2016-2018 | 2010-2020 | 2010- 8- 252-SEA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Colby Blueberg | 23 | P | 6-0 | 185 | R | R | 1993-05-11 | Carson City,NV | AAA | | 2012-2019 | 2014- 24- 717-SDN | Lake Elsinore Storm (A+) |
| Auston Bousfield | 22 | OF | 5-11 | 185 | R | R | 1993-07-05 | Oakland,FL | AAA | | 2012-2018 | 2014- 5- 147-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Rod Boykin | 21 | OF | 6-1 | 175 | R | R | 1995-04-17 | Montgomery,AL | AA | | 2013-2018 | 2013- 12- 358-SDN | Fort Wayne TinCaps (A) |
| Yimmi Brasoban | 22 | P | 6-1 | 185 | R | R | 1994-06-22 | San Cristobal,DR | AA | | 2011-2018 | 2011- UDFA -SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Daniel Bravo | 21 | SS | 6-0 | 160 | R | R | 1995-02-16 | Ocumare de la Costa,VZ | A+ | | 2012-2016 | 2011- UDFA -SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Ryan Buchter | 29 | P | 6-4 | 230 | L | L | 1987-02-13 | Reading,PA | MLB | 2014-2021 | 2006-2021 | 2005- 33- 984-WAS | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Aldemar Burgos | 19 | OF | 6-0 | 165 | R | R | 1997-01-23 | San Juan,PR | A+ | | 2015-2019 | 2015- 8- 237-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Edward Burgos | 19 | OF | 6-2 | 175 | L | L | 1996-08-24 | Santiago,DR | Rk | | 2015-2017 | | Dominican Padres (Rk) |
| Jose Cabrera | 17 | P | 6-0 | 170 | L | L | 1998-09-26 | Puerto La Cruz,VZ | Rk | | 2016-2018 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Leonel Campos | 28 | P | 6-2 | 215 | R | R | 1987-07-17 | Valera,VZ | MLB | 2014-2017 | 2011-2021 | 2010- UDFA -SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Tre Carter | 19 | CF | 6-2 | 181 | L | R | 1997-03-22 | Columbus,IN | A | | 2016-2019 | 2016- 11- 324-SDN | Arizona Padres (Rk) |
| Andrew Cashner | 29 | P | 6-6 | 235 | R | R | 1986-09-11 | Conroe,TX | MLB | 2010-2019 | 2008-2019 | 2008- 1- 19-CHN | San Diego Padres (MLB) ... Lake Elsinore Storm (A+) |
| Fabio Castillo | 27 | P | 6-1 | 235 | R | R | 1989-02-19 | Samana,DR | MLB | 2017-2017 | 2006-2018 | 2005- UDFA -TEX | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Jose Castillo | 20 | P | 6-6 | 252 | L | L | 1996-01-10 | Valencia,VZ | MLB | 2018-2025 | 2013-2025 | 2012- UDFA -TBA | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Adam Cimber | 25 | P | 6-3 | 195 | R | R | 1990-08-15 | Portland,OR | MLB | 2018-2024 | 2010-2024 | 2013- 9- 268-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Emmanuel Clase | 18 | P | 6-2 | 206 | R | R | 1998-03-18 | Rio San Juan,DR | MLB | 2019-2025 | 2015-2025 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Paul Clemens | 28 | P | 6-3 | 215 | R | R | 1988-02-14 | Columbia,NC | MLB | 2013-2016 | 2008-2019 | 2008- 7- 220-ATL | San Diego Padres (MLB) |
| Ronaldo Contreras | 19 | OF | 6-3 | 195 | R | R | 1996-07-15 | Higuey,DR | Rk | | 2013-2016 | 2012- UDFA -SDN | Arizona Padres (Rk) |
| Franchy Cordero | 21 | 1B-RF | 6-3 | 225 | L | R | 1994-09-02 | Azua,DR | MLB | 2017-2023 | 2012-2025 | 2011- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Starlin Cordero | 17 | P | 6-7 | 220 | R | R | 1998-07-21 | San Cristobal,DR | A- | | 2015-2019 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Jarred Cosart | 26 | P | 6-3 | 206 | R | R | 1990-05-25 | League City,TX | MLB | 2013-2017 | 2009-2017 | 2008- 38-1156-PHI | San Diego Padres (MLB) |
| Jean Cosme | 20 | P | 6-2 | 155 | R | R | 1996-05-24 | Toa Alta,PR | AA | | 2014-2019 | 2014- 17- 511-BAL | Fort Wayne TinCaps (A) |
| Taylor Cox | 22 | P | 6-3 | 210 | L | L | 1993-07-02 | Bartlett,TN | A+ | | 2012-2016 | 2014- 16- 477-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Aaron Cressley | 23 | P | 6-1 | 175 | L | R | 1992-09-02 | Corry,PA | A+ | | 2014-2016 | 2014- 26- 777-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Dan Dallas | 18 | P | 6-2 | 235 | R | L | 1997-12-24 | Buffalo,NY | AAA | | 2016-2019 | 2016- 7- 204-SDN | Arizona Padres (Rk) |
| Adrian De Horta | 21 | P | 6-3 | 185 | R | R | 1995-03-13 | La Puente,CA | AAA | | 2013-2025 | 2013- 8- 238-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Wilfri De La Cruz | 22 | C | 5-11 | 180 | R | R | 1993-12-29 | Mao,DR | A+ | | 2013-2017 | 2012- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Enyel De Los Santos | 20 | P | 6-3 | 235 | R | R | 1995-12-25 | San Pedro de Macoris,DR | MLB | 2018-2025 | 2015-2025 | 2014- UDFA -SEA | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Jose Rafael De Paula | 25 | P | 6-2 | 215 | R | R | 1991-03-24 | La Victoria,DR | AAA | | 2012-2019 | 2010- UDFA -NYA | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Miguel Del Castillo | 24 | C | 5-10 | 170 | R | R | 1991-10-14 | Santo Domingo,DR | AAA | | 2010-2017 | 2009- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Manny DeLeon | 23 | OF | 6-1 | 195 | L | R | 1993-04-11 | New York,NY | A- | | 2016-2017 | 2016- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Luis Diaz | 24 | P | 6-4 | 209 | R | R | 1992-04-09 | Valencia,VZ | AAA | | 2010-2019 | 2008- UDFA -BOS | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Arizona Padres (Rk) |
| Alex Dickerson | 26 | LF | 6-2 | 226 | L | L | 1990-05-26 | Poway,CA | MLB | 2015-2022 | 2009-2025 | 2011- 3- 91-PIT | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Michael Dimock | 26 | P | 6-2 | 195 | R | R | 1989-10-26 | Greensboro,NC | AAA | | 2009-2018 | 2012- 37-1119-HOU | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Dominic DiSabatino | 20 | P | 6-5 | 190 | R | R | 1996-03-21 | Middletown,DE | A- | | 2016-2023 | 2016- 20- 594-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Louis Distasio | 22 | P | 6-4 | 195 | R | R | 1994-02-05 | Portland,ME | AAA | | 2013-2017 | 2015- 32- 957-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Jose Dominguez | 25 | P | 6-0 | 200 | R | R | 1990-08-07 | San Pedro de Macoris,DR | MLB | 2013-2016 | 2010-2019 | 2007- UDFA -LAN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Thomas Dorminy | 24 | P | 6-0 | 190 | L | L | 1992-06-01 | Lutz,FL | AAA | | 2013-2025 | 2014- 10- 297-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Nate Easley | 20 | 2B | 5-10 | 170 | R | R | 1996-01-11 | Glendale,AZ | AA | | 2016-2021 | 2016- 23- 684-SDN | Tri-City Dust Devils (A-) |
| Jon Edwards | 28 | P | 6-5 | 240 | R | R | 1988-01-08 | Chicago,IL | MLB | 2014-2019 | 2006-2021 | 2006- 14- 436-SLN | Lake Elsinore Storm (A+) |
| Derek Eitel | 28 | P | 6-4 | 200 | R | R | 1987-11-21 | Marshall,IL | AAA | | 2010-2017 | 2010- 17- 511-ARI | El Paso Chihuahuas (AAA) |
| Dalton Erb | 22 | P | 6-8 | 250 | R | R | 1994-05-13 | Torrance,CA | A+ | | 2013-2018 | 2016- 30- 894-SDN | Tri-City Dust Devils (A-) |
| Robbie Erlin | 25 | P | 5-11 | 200 | R | L | 1990-10-08 | Oakland,CA | MLB | 2013-2022 | 2009-2023 | 2009- 3- 93-TEX | San Diego Padres (MLB) |
| Anderson Espinoza | 18 | P | 6-0 | 190 | R | R | 1998-03-09 | Caracas,VZ | MLB | 2022-2022 | 2015-2025 | 2014- UDFA -BOS | Fort Wayne TinCaps (A) |
| Juan Fernandez | 17 | 1B-3B | 5-7 | 205 | R | R | 1999-03-07 | Valencia,VZ | AAA | | 2016-2025 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Omar Fernandez | 17 | P | 5-11 | 160 | L | L | 1999-04-20 | Carora,VZ | Rk | | 2016-2018 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Chasen Ford | 20 | P | 6-3 | 200 | R | R | 1995-07-18 | Lake Forest,CA | A- | | 2014-2017 | 2016- 27- 804-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Nathan Foriest | 24 | P | 6-2 | 190 | R | L | 1992-01-28 | Kingston Springs,TN | A+ | | 2012-2021 | 2015- 35-1047-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Ty France | 21 | 1B | 5-11 | 215 | R | R | 1994-07-13 | Downey,CA | MLB | 2019-2025 | 2013-2025 | 2015- 34-1017-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Yordi Francisco | 19 | OF | 6-1 | 175 | L | R | 1997-03-14 | Santiago,DR | Rk | | 2016-2022 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Christian Friedrich | 28 | P | 6-4 | 222 | R | L | 1987-07-08 | Evanston,IL | MLB | 2012-2016 | 2006-2021 | 2008- 1- 25-COL | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... Lake Elsinore Storm (A+) |
| Rocky Gale | 28 | C | 6-1 | 185 | R | R | 1988-02-22 | Portland,OR | MLB | 2015-2019 | 2007-2021 | 2010- 24- 724-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Frank Garces | 26 | P | 5-11 | 175 | L | L | 1990-01-17 | San Cristobal,DR | MLB | 2014-2015 | 2011-2021 | 2009- UDFA -TEX | El Paso Chihuahuas (AAA) |
| Alan Garcia | 19 | OF | 6-0 | 220 | L | L | 1997-01-31 | Nogales,AZ | AAA | | 2015-2025 | 2015- 19- 567-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Jaffe Garcia | 20 | OF | 6-1 | 175 | R | R | 1996-03-13 | Margarita,VZ | Rk | | 2015-2017 | | Dominican Padres (Rk) |
| Jean Garcia | 19 | P | 6-5 | 220 | R | R | 1996-12-07 | Santiago,DR | A- | | 2014-2017 | 2014- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Kyle Gauthier | 22 | P | 6-4 | 220 | R | R | 1994-04-08 | Salem,MA | Rk | | 2013-2016 | 2016- UDFA -SDN | Arizona Padres (Rk) |
| Michael Gettys | 20 | P | 6-1 | 217 | R | R | 1995-10-22 | Gainesville,GA | AAA | | 2014-2022 | 2014- 2- 51-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Ruddy Giron | 19 | SS | 6-0 | 205 | R | R | 1997-01-04 | Santo Domingo,DR | AA | | 2014-2019 | 2013- UDFA -SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Cesar Gonzalez | 17 | P | 6-1 | 160 | R | R | 1999-02-24 | Maracay,VZ | Rk | | 2016-2018 | | Dominican Padres (Rk) |
| Diego Goris | 25 | 1B-2B | 5-11 | 200 | R | R | 1990-11-08 | Santiago,DR | AAA | | 2010-2023 | 2008- UDFA -PIT | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Denzell Gowdy | 19 | 3B | 5-11 | 185 | R | R | 1996-11-30 | Sylvester,GA | Rk | | 2016-2017 | 2016- 34-1014-SDN | Arizona Padres (Rk) |
| Marcus Greene | 21 | C | 5-11 | 195 | R | R | 1994-08-19 | Pomona,CA | A+ | | 2013-2018 | 2013- 16- 490-TEX | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Oliver Grullart | 19 | P | 6-1 | 165 | R | R | 1997-03-23 | Santo Domingo,DR | Rk | | 2016-2016 | | Dominican Padres (Rk) |
| Javy Guerra | 20 | P | 6-0 | 190 | L | R | 1995-09-25 | David,PN | MLB | 2018-2023 | 2013-2025 | 2012- UDFA -BOS | Lake Elsinore Storm (A+) |
| Jordan Guerrero | 19 | P | 6-5 | 296 | R | R | 1996-08-01 | Sarasota,FL | AAA | | 2015-2023 | 2015- 6- 177-SDN | Tri-City Dust Devils (A-) |
| Tayron Guerrero | 25 | P | 6-8 | 225 | R | R | 1991-01-09 | Boca Chica,CB | MLB | 2016-2019 | 2010-2025 | 2009- UDFA -SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Jeremy Guthrie | 37 | P | 6-1 | 205 | R | R | 1979-04-08 | Roseburg,OR | MLB | 2004-2017 | 1998-2017 | 2002- 1- 22-CLE | El Paso Chihuahuas (AAA) |
| Jonathan Guzman | 21 | P | 5-10 | 205 | R | R | 1995-02-08 | San Cristobal,DR | A | | 2015-2019 | 2015- UDFA -SDN | Arizona Padres (Rk) ... Dominican Padres (Rk) |
| Luis Guzman | 18 | IF | 6-2 | 175 | R | R | 1998-06-20 | Santo Domingo,DR | A+ | | 2015-2018 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Oliber Guzman | 19 | P | 5-11 | 180 | R | R | 1997-03-15 | Esperanza,DR | Rk | | 2015-2019 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Jason Hagerty | 28 | C | 6-3 | 230 | B | R | 1987-09-13 | St. Louis,MO | AAA | | 2007-2016 | 2009- 5- 144-SDN | El Paso Chihuahuas (AAA) |
| Justin Hancock | 25 | P | 6-4 | 185 | R | R | 1990-10-28 | Defiance,OH | MLB | 2018-2018 | 2011-2019 | 2011- 9- 293-SDN | El Paso Chihuahuas (AAA) |
| Brad Hand | 26 | P | 6-3 | 224 | L | L | 1990-03-20 | Minneapolis,MN | MLB | 2011-2023 | 2008-2023 | 2008- 2- 52-MIA | San Diego Padres (MLB) |
| Will Headean | 22 | P | 6-4 | 230 | R | L | 1993-10-11 | West Lafayette,IN | A+ | | 2013-2019 | 2015- 13- 387-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Austin Hedges | 23 | C | 6-0 | 220 | R | R | 1992-08-18 | San Juan Capistrano,CA | MLB | 2015-2025 | 2011-2025 | 2011- 2- 82-SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Johnny Hellweg | 27 | P | 6-8 | 220 | R | R | 1988-10-29 | Ann Arbor,MI | MLB | 2013-2013 | 2008-2021 | 2008- 16- 499-ANA | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Henry Henry | 17 | P | 6-4 | 215 | R | R | 1998-12-17 | San Cristobal,DR | AA | | 2016-2025 | 2015- UDFA -SDN | Dominican Padres (Rk) ... Arizona Padres (Rk) |
| Adolfo Hernandez | 18 | P | 5-11 | 165 | L | L | 1997-07-23 | Torreon,MX | Rk | | 2016-2016 | | Dominican Padres (Rk) |
| Jose Hernandez | 17 | P | 6-1 | 165 | R | R | 1998-08-06 | Puerto Cabello,VZ | Rk | | 2016-2016 | | Dominican Padres (Rk) |
| Keith Hessler | 27 | P | 6-4 | 244 | L | L | 1989-03-15 | Washington,DC | MLB | 2015-2016 | 2009-2018 | 2010- 28- 841-ARI | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Chris Huffman | 23 | P | 6-1 | 205 | R | R | 1992-11-25 | Fort Defiance,VA | AAA | | 2012-2018 | 2014- 14- 417-SDN | Lake Elsinore Storm (A+) |
| Reinaldo Ilarraza | 17 | CF-2B | 5-10 | 150 | B | R | 1999-01-12 | San Felipe,VZ | AAA | | 2016-2022 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Edwin Jackson | 32 | P | 6-2 | 215 | R | R | 1983-09-09 | Neu-Ulm,GE | MLB | 2003-2019 | 2001-2021 | 2001- 6- 190-LAN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Travis Jankowski | 25 | RF-LF | 6-3 | 195 | L | R | 1991-06-15 | Ephrata,PA | MLB | 2015-2025 | 2010-2025 | 2012- 1- 44-SDN | San Diego Padres (MLB) |
| Jon Jay | 31 | LF-CF | 5-11 | 200 | L | L | 1985-03-15 | Miami,FL | MLB | 2010-2021 | 2004-2021 | 2006- 2- 74-SLN | San Diego Padres (MLB) ... Lake Elsinore Storm (A+) |
| Chase Jensen | 25 | 3B | 6-4 | 195 | R | R | 1991-01-29 | Riverside,CA | AA | | 2011-2016 | 2013- 22- 658-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Arizona Padres (Rk) |
| Jason Jester | 25 | P | 5-11 | 205 | R | R | 1991-05-04 | Longview,TX | AAA | | 2013-2018 | 2014- 23- 687-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Erik Johnson | 26 | P | 6-3 | 230 | R | R | 1989-12-30 | Mountain View,CA | MLB | 2013-2016 | 2009-2018 | 2011- 2- 80-CHA | San Diego Padres (MLB) |
| Duanel Jones | 23 | 3B | 6-3 | 220 | R | R | 1993-05-11 | Samana,DR | AA | | 2010-2016 | 2010- UDFA -SDN | San Antonio Missions (AA) |
| Jerry Keel | 22 | P | 6-6 | 240 | L | L | 1993-09-26 | Palmdale,CA | AAA | | 2012-2022 | 2015- 9- 267-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Michael Kelly | 23 | P | 6-4 | 185 | R | R | 1992-09-06 | Boynton Beach,FL | MLB | 2022-2025 | 2012-2025 | 2011- 1- 48-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Matt Kemp | 31 | CF | 6-4 | 225 | R | R | 1984-09-23 | Midwest City,OK | MLB | 2006-2020 | 2003-2020 | 2003- 6- 181-LAN | San Diego Padres (MLB) |
| A.J. Kennedy | 22 | C | 6-0 | 190 | R | R | 1994-01-23 | Irvine,CA | AAA | | 2013-2019 | 2015- 30- 897-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Brett Kennedy | 21 | P | 6-0 | 200 | R | R | 1994-08-04 | Pomona,NJ | MLB | 2018-2023 | 2013-2024 | 2015- 11- 327-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Corey Kimber | 22 | P | 6-1 | 175 | R | R | 1994-06-28 | Greensboro,NC | A+ | | 2012-2018 | 2012- 25- 765-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Michael Kirkman | 29 | P | 6-4 | 215 | L | L | 1986-09-18 | Lake City,FL | MLB | 2010-2016 | 2005-2016 | 2005- 5- 159-TEX | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Patrick Kivlehan | 26 | 1B-P | 6-2 | 215 | R | R | 1989-12-22 | Nyack,NY | MLB | 2016-2021 | 2012-2023 | 2012- 4- 131-SEA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Taylor Kohlwey | 21 | LF-RF | 6-2 | 200 | L | L | 1994-07-20 | Holmen,WI | MLB | 2023-2023 | 2013-2025 | 2016- 21- 624-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Dinelson Lamet | 23 | P | 6-3 | 228 | R | R | 1992-07-18 | Santiago,DR | MLB | 2017-2024 | 2014-2025 | 2014- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Eric Lauer | 21 | P | 6-3 | 209 | R | L | 1995-06-03 | Elyria,OH | MLB | 2018-2025 | 2014-2025 | 2016- 1- 25-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Reggie Lawson | 18 | P | 6-4 | 205 | R | R | 1997-08-02 | Victorville,CA | AA | | 2016-2024 | 2016- 2- 71-SDN | Arizona Padres (Rk) |
| Zech Lemond | 23 | P | 6-1 | 170 | R | R | 1992-10-09 | Houston,TX | AA | | 2012-2019 | 2014- 3- 86-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Aaron Lezama | 19 | P | 6-5 | 180 | L | L | 1997-04-22 | Caracas,VZ | Rk | | 2016-2017 | | Dominican Padres (Rk) |
| Jose Lezama | 18 | C | 5-10 | 195 | B | R | 1998-02-19 | Maracay,VZ | A | | 2015-2019 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Taylor Lindsey | 24 | 2B | 6-0 | 195 | L | R | 1991-12-02 | Scottsdale,AZ | AAA | | 2010-2016 | 2010- 1- 37-ANA | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Elvin Liriano | 23 | P | 6-3 | 190 | L | L | 1992-10-17 | San Cristobal,DR | AAA | | 2011-2024 | 2010- UDFA -SDN | Fort Wayne TinCaps (A) |
| Kyle Lloyd | 25 | P | 6-4 | 220 | R | R | 1990-10-16 | Sacramento,CA | MLB | 2017-2017 | 2010-2019 | 2013- 29- 868-SDN | San Antonio Missions (AA) |
| Walker Lockett | 22 | P | 6-5 | 225 | R | R | 1994-05-03 | Jacksonville,FL | MLB | 2018-2020 | 2012-2024 | 2012- 4- 135-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| James Loney | 32 | 1B | 6-3 | 235 | L | L | 1984-05-07 | Houston,TX | MLB | 2006-2016 | 2002-2019 | 2002- 1- 19-LAN | El Paso Chihuahuas (AAA) |
| Diomar Lopez | 19 | P | 5-11 | 165 | R | R | 1996-12-15 | Larreynaga,NI | AAA | | 2014-2022 | 2013- UDFA -SDN | Tri-City Dust Devils (A-) |
| Braxton Lorenzini | 21 | P | 6-4 | 172 | R | R | 1995-04-05 | Aurora,CO | A+ | | 2015-2021 | 2015- 33- 987-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Joey Lucchesi | 23 | P | 6-5 | 228 | L | L | 1993-06-06 | Newark,CA | MLB | 2018-2025 | 2014-2025 | 2016- 4- 114-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Seth Lucio | 23 | P-IF | 5-10 | 180 | R | R | 1993-04-30 | Locust Grove,GA | A | | 2012-2019 | 2014- 12- 357-SDN | Arizona Padres (Rk) |
| Cristian Machuca | 19 | P | 6-1 | 165 | L | L | 1997-04-24 | San Cristobal,DR | Rk | | 2015-2017 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Westhers Magdaleno | 19 | SS | 6-1 | 190 | R | R | 1996-10-30 | Santo Domingo,DR | A+ | | 2014-2017 | 2013- UDFA -SDN | Lake Elsinore Storm (A+) ... Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Josh Magee | 19 | OF | 5-10 | 185 | R | R | 1997-02-13 | Covington,LA | A+ | | 2015-2017 | 2015- 5- 147-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Manuel Margot | 21 | LF-RF | 5-10 | 229 | R | R | 1994-09-28 | San Cristobal,DR | MLB | 2016-2025 | 2012-2025 | 2011- UDFA -BOS | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Alam Martinez | 19 | OF | 6-2 | 208 | R | R | 1997-06-13 | Santo Domingo,DR | Rk | | 2016-2016 | | Dominican Padres (Rk) |
| Alberth Martinez | 25 | OF | 6-1 | 170 | R | R | 1991-01-23 | San Felix,VZ | AAA | | 2010-2025 | 2009- UDFA -SDN | San Antonio Missions (AA) |
| Luis Martinez | 20 | P | 5-11 | 184 | R | R | 1995-12-01 | Caracas,VZ | Rk | | 2016-2016 | | Dominican Padres (Rk) |
| Phil Maton | 23 | P | 6-2 | 206 | R | R | 1993-03-25 | Paducah,KY | MLB | 2017-2025 | 2012-2025 | 2015- 20- 597-SDN | El Paso Chihuahuas (AAA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Chris Mattison | 22 | C | 6-4 | 215 | R | R | 1994-04-16 | Lancaster,PA | A- | | 2016-2017 | 2016- 16- 474-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Brandon Maurer | 25 | P | 6-5 | 225 | R | R | 1990-07-03 | Newport Beach,CA | MLB | 2013-2018 | 2008-2019 | 2008- 23- 702-SEA | San Diego Padres (MLB) |
| Cory Mazzoni | 26 | P | 6-1 | 210 | R | R | 1989-10-19 | Evans City,PA | MLB | 2015-2018 | 2009-2018 | 2011- 2- 71-NYN | El Paso Chihuahuas (AAA) |
| Daniel McCutchen | 33 | P | 6-2 | 215 | R | R | 1982-09-26 | McKinney,TX | MLB | 2009-2014 | 2002-2016 | 2006- 13- 404-NYA | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Jim McDade | 23 | P | 6-5 | 190 | L | R | 1992-12-01 | Langhorne,PA | A | | 2016-2017 | 2016- UDFA -SDN | Arizona Padres (Rk) |
| Casey McElroy | 26 | 2B | 5-8 | 180 | L | R | 1989-12-28 | Bakersfield,CA | AAA | | 2009-2016 | 2011- 11- 353-SDN | El Paso Chihuahuas (AAA) |
| Kyle McGrath | 23 | P | 6-2 | 185 | L | L | 1992-07-31 | Louisville,KY | MLB | 2017-2018 | 2011-2021 | 2014- 36-1077-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Trey McNutt | 26 | P | 6-2 | 229 | R | R | 1989-08-02 | Birmingham,AL | AAA | | 2009-2019 | 2009- 32- 980-CHN | San Antonio Missions (AA) ... Arizona Padres (Rk) |
| Angel Mejia | 21 | P | 6-0 | 160 | R | R | 1995-02-10 | Peravia,DR | A+ | | 2013-2018 | 2014- UDFA -SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Kelvin Melean | 17 | 2B-3B | 5-10 | 195 | R | R | 1998-09-05 | Guatire,VZ | AAA | | 2016-2025 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Evan Miller | 21 | P | 6-2 | 197 | L | R | 1995-05-23 | LaPorte,IN | AAA | | 2015-2022 | 2016- 22- 654-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Ryan Miller | 23 | C | 6-2 | 200 | R | R | 1992-11-17 | Hemet,CA | AA | | 2013-2016 | 2013- 14- 418-SDN | San Antonio Missions (AA) |
| Euri Minaya | 20 | RF-OF | 6-4 | 205 | R | R | 1995-10-11 | Santo Domingo Este,DR | Rk | | 2013-2016 | 2012- UDFA -SDN | Arizona Padres (Rk) |
| Nick Monroe | 22 | P | 6-4 | 235 | R | R | 1994-03-06 | Greenville,SC | A | | 2013-2017 | 2015- 21- 627-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Tyler Moore | 23 | 2B | 5-8 | 165 | R | R | 1993-05-28 | Evans,GA | A | | 2013-2016 | 2015- 29- 867-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Edwin Moreno | 22 | OF | 6-1 | 190 | L | L | 1993-10-27 | Villa Mella,DR | AAA | | 2011-2017 | 2010- UDFA -SDN | Lake Elsinore Storm (A+) |
| Elliot Morris | 24 | P | 6-4 | 210 | R | R | 1992-04-26 | Renton,WA | AA | | 2013-2016 | 2013- 4- 127-ANA | San Antonio Missions (AA) ... Fort Wayne TinCaps (A) |
| Brandon Morrow | 31 | P | 6-3 | 207 | R | R | 1984-07-26 | Santa Rosa,CA | MLB | 2007-2018 | 2004-2018 | 2006- 1- 5-SEA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Arizona Padres (Rk) |
| Bryce Morrow | 28 | P | 6-2 | 200 | R | R | 1988-01-02 | Grand Rapids,MI | AAA | | 2007-2017 | 2013- UDFA -SDN | San Antonio Missions (AA) |
| Daniel Moskos | 30 | P | 6-1 | 200 | R | L | 1986-04-28 | Greenville,SC | MLB | 2011-2011 | 2005-2018 | 2007- 1- 4-PIT | El Paso Chihuahuas (AAA) |
| Andres Munoz | 17 | P | 6-2 | 222 | R | R | 1999-01-16 | Los Mochis,MX | MLB | 2019-2025 | 2016-2025 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Wil Myers | 25 | RF-1B | 6-3 | 207 | R | R | 1990-12-10 | Thomasville,NC | MLB | 2013-2023 | 2009-2023 | 2009- 3- 91-KCA | San Diego Padres (MLB) |
| Josh Naylor | 19 | 1B | 5-10 | 235 | L | L | 1997-06-22 | Mississauga,ON | MLB | 2019-2025 | 2015-2025 | 2015- 1- 12-MIA | Lake Elsinore Storm (A+) |
| Jacob Nix | 20 | P | 6-4 | 220 | R | R | 1996-01-09 | Los Alamitos,CA | MLB | 2018-2018 | 2015-2025 | 2015- 3- 86-SDN | Fort Wayne TinCaps (A) |
| Nick Noonan | 27 | 2B | 6-1 | 185 | L | R | 1989-05-04 | Poway,CA | MLB | 2013-2016 | 2007-2018 | 2007- 1- 32-SFN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Derek Norris | 27 | C | 6-0 | 235 | R | R | 1989-02-14 | Goddard,KS | MLB | 2012-2017 | 2007-2018 | 2007- 4- 130-WAS | San Diego Padres (MLB) |
| Aaron Northcraft | 26 | P | 6-3 | 229 | R | R | 1990-05-28 | Tucson,AZ | MLB | 2021-2021 | 2009-2022 | 2009- 10- 298-ATL | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Dayon Olmo | 19 | OF | 5-11 | 165 | B | R | 1996-11-15 | Boca Chica,DR | Rk | | 2014-2017 | 2013- UDFA -SDN | Arizona Padres (Rk) |
| Mike Olt | 27 | 3B | 6-2 | 210 | R | R | 1988-08-27 | New Haven,CT | MLB | 2012-2015 | 2008-2019 | 2010- 1- 49-TEX | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Ariel Ortega | 19 | SS | 5-10 | 150 | R | R | 1997-06-20 | Panama City,PN | Rk | | 2015-2016 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Kyle Overstreet | 22 | 1B | 5-11 | 205 | R | R | 1993-09-04 | Birmingham,AL | AA | | 2013-2021 | 2015- 14- 417-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Chris Paddack | 20 | P | 6-5 | 217 | R | R | 1996-01-08 | Austin,TX | MLB | 2019-2025 | 2015-2025 | 2015- 8- 236-MIA | Fort Wayne TinCaps (A) |
| Ben Paullus | 26 | P | 6-1 | 190 | R | R | 1989-08-31 | Olive Branch,MS | AA | | 2009-2016 | 2011- 19- 599-NYA | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Jhonatan Pena | 22 | OF | 6-2 | 180 | R | R | 1994-04-18 | Peravia,DR | A | | 2013-2016 | 2012- UDFA -SDN | Fort Wayne TinCaps (A) |
| Tucker Pennell | 22 | C | 6-2 | 200 | R | R | 1994-04-07 | Austin,TX | Rk | | 2013-2018 | 2016- UDFA -SDN | Arizona Padres (Rk) |
| Luis Perdomo | 23 | P | 6-2 | 218 | R | R | 1993-05-09 | Santo Domingo,DR | MLB | 2016-2022 | 2011-2025 | 2010- UDFA -SLN | San Diego Padres (MLB) |
| Blinger Perez | 17 | C | 6-0 | 170 | R | R | 1998-08-21 | Barquisimeto,VZ | Rk | | 2016-2018 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Fernando Perez | 22 | 3B | 6-0 | 210 | L | R | 1993-09-13 | Ensenada,MX | AAA | | 2012-2024 | 2012- 3- 102-SDN | Lake Elsinore Storm (A+) |
| Mayky Perez | 19 | P | 6-5 | 235 | R | R | 1996-09-26 | San Pedro de Macoris,DR | A | | 2014-2019 | 2013- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Carlos Pimentel | 26 | P | 6-3 | 215 | R | R | 1989-12-01 | Santiago,DR | AAA | | 2007-2021 | 2006- UDFA -TEX | El Paso Chihuahuas (AAA) |
| Jose Pirela | 26 | 2B | 6-0 | 220 | R | R | 1989-11-21 | Valera,VZ | MLB | 2014-2019 | 2008-2025 | 2006- UDFA -NYN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Anderson Polanco | 18 | P | 6-3 | 175 | L | L | 1998-02-05 | Santiago,DR | Rk | | 2016-2019 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Drew Pomeranz | 27 | P | 6-5 | 246 | R | L | 1988-11-22 | Memphis,TN | MLB | 2011-2025 | 2008-2025 | 2010- 1- 5-CLE | San Diego Padres (MLB) |
| Hudson Potts | 17 | 1B-3B | 6-2 | 205 | R | R | 1998-10-28 | Southlake,TX | AAA | | 2016-2023 | 2016- 1- 24-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Evan Powell | 19 | P | 6-9 | 246 | R | R | 1996-11-18 | Old Harbour Bay,JM | Rk | | 2016-2017 | | Dominican Padres (Rk) |
| Kevin Quackenbush | 27 | P | 6-4 | 235 | R | R | 1988-11-28 | Land O'Lakes,FL | MLB | 2014-2021 | 2008-2023 | 2011- 8- 263-SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Cal Quantrill | 21 | P | 6-3 | 195 | L | R | 1995-02-10 | Port Hope,ON | MLB | 2019-2025 | 2014-2025 | 2016- 1- 8-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Gabriel Quintana | 23 | 3B | 6-3 | 215 | R | R | 1992-09-07 | Azua,DR | AAA | | 2010-2018 | 2009- UDFA -SDN | San Antonio Missions (AA) |
| Alexei Ramirez | 34 | SS-3B | 6-2 | 180 | R | R | 1981-09-22 | Pinar del Rio,CU | MLB | 2008-2016 | 2008-2018 | 2008- UDFA -CHA | San Diego Padres (MLB) |
| Emmanuel Ramirez | 21 | P | 6-2 | 190 | R | R | 1994-07-15 | Puerto Plata,DR | MLB | 2024-2024 | 2013-2025 | 2012- UDFA -SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Jordis Ramos | 20 | P | 6-10 | 194 | L | L | 1996-06-15 | Santiago,DR | Rk | | 2015-2017 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Colin Rea | 25 | P | 6-5 | 220 | R | R | 1990-07-01 | Cascade,IA | MLB | 2015-2025 | 2009-2025 | 2011- 12- 383-SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Hunter Redman | 23 | C | 5-10 | 180 | R | R | 1992-08-25 | Lubbock,TX | AAA | | 2012-2016 | 2014- 8- 249-LAN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Michael Reed | 21 | CF-RF | 6-4 | 218 | B | R | 1995-04-27 | Bronx,NY | AAA | | 2014-2025 | 2016- 2- 48-SDN | Tri-City Dust Devils (A-) |
| Hunter Renfroe | 24 | RF | 6-1 | 230 | R | R | 1992-01-28 | Crystal Springs,MS | MLB | 2016-2025 | 2011-2025 | 2013- 1- 13-SDN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Franmil Reyes | 20 | DH | 6-5 | 265 | R | R | 1995-07-07 | Palenque,DR | MLB | 2018-2023 | 2012-2025 | 2011- UDFA -SDN | Lake Elsinore Storm (A+) |
| Gerardo Reyes | 23 | P | 5-11 | 195 | R | R | 1993-05-13 | Ciudad Victoria,MX | MLB | 2019-2024 | 2013-2025 | 2013- UDFA -TBA | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Greg Reynolds | 30 | P | 6-7 | 225 | R | R | 1985-07-03 | Pacifica,CA | MLB | 2008-2013 | 2004-2016 | 2006- 1- 2-COL | El Paso Chihuahuas (AAA) |
| Clayton Richard | 32 | P | 6-5 | 240 | L | L | 1983-09-12 | Lafayette,IN | MLB | 2008-2019 | 2005-2019 | 2005- 8- 245-CHA | San Diego Padres (MLB) |
| Carlos Rivera | 21 | P | 6-3 | 190 | R | R | 1995-06-08 | San Pedro de Macoris,DR | Rk | | 2015-2017 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Fernando Rodney | 39 | P | 5-11 | 240 | R | R | 1977-03-18 | Samana,DR | MLB | 2002-2019 | 1999-2023 | 1997- UDFA -DET | San Diego Padres (MLB) |
| Bryan Rodriguez | 24 | P | 6-5 | 180 | R | R | 1991-07-06 | San Pedro de Macoris,DR | AAA | | 2010-2025 | 2010- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Hansel Rodriguez | 19 | P | 6-2 | 170 | R | R | 1997-02-27 | Santo Domingo,DR | AA | | 2014-2023 | 2014- UDFA -TOR | Tri-City Dust Devils (A-) |
| Blake Rogers | 22 | P | 6-2 | 200 | R | R | 1994-02-23 | Lewisville,TX | AAA | | 2014-2025 | 2015- 37-1107-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Miguel Roman | 19 | P | 6-1 | 170 | R | R | 1997-02-23 | Valencia,VZ | Rk | | 2016-2017 | | Dominican Padres (Rk) |
| Jose Rondon | 22 | 3B-SS | 6-1 | 215 | R | R | 1994-03-03 | Villa de Cura,CU | MLB | 2016-2021 | 2011-2025 | 2011- UDFA -ANA | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Adam Rosales | 33 | SS | 6-2 | 200 | R | R | 1983-05-20 | Chicago,IL | MLB | 2008-2018 | 2002-2019 | 2005- 12- 362-CIN | San Diego Padres (MLB) |
| Eguy Rosario | 16 | 3B | 5-9 | 150 | R | R | 1999-08-25 | Juan Baron,DR | MLB | 2022-2024 | 2016-2025 | 2015- UDFA -SDN | Dominican Padres (Rk) ... Arizona Padres (Rk) |
| Seth Rosin | 27 | P | 6-6 | 265 | R | R | 1988-11-02 | Fargo,ND | MLB | 2014-2015 | 2008-2017 | 2010- 4- 138-SFN | El Paso Chihuahuas (AAA) |
| Tyson Ross | 29 | P | 6-5 | 254 | R | R | 1987-04-22 | Berkeley,CA | MLB | 2010-2019 | 2006-2019 | 2008- 2- 58-OAK | San Diego Padres (MLB) ... Lake Elsinore Storm (A+) |
| Jose Ruiz | 21 | P | 6-1 | 245 | R | R | 1994-10-21 | Guacara,VZ | MLB | 2017-2025 | 2012-2025 | 2011- UDFA -SDN | Lake Elsinore Storm (A+) ... Tri-City Dust Devils (A-) |
| Elvis Sabala | 18 | SS | 6-1 | 178 | R | R | 1997-09-26 | Santo Domingo,DR | A- | | 2015-2018 | 2014- UDFA -SDN | Dominican Padres (Rk) |
| Elier Sanchez | 29 | P | 6-2 | 230 | L | L | 1986-10-04 | Havana,CU | AA | | 2016-2016 | 2016- UDFA -SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Tri-City Dust Devils (A-) |
| Hector Sanchez | 26 | C | 6-0 | 220 | B | R | 1989-11-17 | Maracay,VZ | MLB | 2011-2017 | 2009-2024 | 2006- UDFA -SFN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Adonis Santana | 17 | P | 6-1 | 160 | R | R | 1998-09-10 | San Francisco de Macoris,DR | Rk | | 2016-2017 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Angel Santos | 20 | OF | 6-4 | 170 | L | R | 1996-01-13 | La Vega,DR | Rk | | 2015-2017 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Trae Santos | 23 | 1B | 6-1 | 235 | L | L | 1992-10-11 | Barrigada,GU | AA | | 2013-2019 | 2013- 17- 508-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Luis Sardinas | 23 | SS | 6-1 | 180 | B | R | 1993-05-16 | Bolivar,VZ | MLB | 2014-2018 | 2010-2025 | 2009- UDFA -TEX | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Josh Satin | 31 | 1B | 6-2 | 215 | R | R | 1984-12-23 | Hidden Hills,CA | MLB | 2011-2014 | 2004-2016 | 2008- 6- 194-NYN | El Paso Chihuahuas (AAA) |
| Jose Savinon | 20 | SS | 6-0 | 160 | L | R | 1996-02-17 | Bani,DR | A- | | 2014-2018 | 2014- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Ryan Schimpf | 28 | 3B-2B | 5-9 | 180 | L | R | 1988-04-11 | New Orleans,LA | MLB | 2016-2018 | 2007-2018 | 2009- 5- 160-TOR | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Jesse Scholtens | 22 | P | 6-4 | 240 | R | R | 1994-04-06 | Fairfield,CA | MLB | 2023-2025 | 2013-2025 | 2016- 9- 264-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Nick Schulz | 25 | OF | 6-3 | 210 | R | R | 1991-05-03 | Mountain View,CA | AAA | | 2010-2019 | 2014- UDFA -SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Trevor Seidenberger | 24 | P | 6-2 | 200 | L | L | 1992-06-09 | Pflugerville,TX | AA | | 2012-2016 | 2013- 12- 362-MIL | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Tri-City Dust Devils (A-) |
| Tyler Selesky | 22 | IF | 6-0 | 192 | L | R | 1993-10-06 | Macon,GA | A+ | | 2013-2017 | 2016- UDFA -SDN | Fort Wayne TinCaps (A) ... Arizona Padres (Rk) |
| Ben Sheckler | 21 | P | 6-8 | 276 | L | L | 1995-05-12 | Sparta,MI | A+ | | 2016-2018 | 2016- 8- 234-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| James Shields | 34 | P | 6-3 | 210 | R | R | 1981-12-20 | Newhall,CA | MLB | 2006-2018 | 2001-2018 | 2000- 16- 466-TBA | San Diego Padres (MLB) |
| Seth Simmons | 28 | P | 5-9 | 170 | R | R | 1988-06-14 | Winston-Salem,NC | AAA | | 2008-2019 | 2011- 40-1204-ARI | San Antonio Missions (AA) |
| Austin Smith | 19 | P | 6-4 | 250 | R | R | 1996-07-09 | Boynton Beach,FL | A+ | | 2015-2022 | 2015- 2- 51-SDN | Fort Wayne TinCaps (A) |
| Jake Smith | 26 | P | 6-4 | 190 | R | R | 1990-06-02 | North Augusta,SC | MLB | 2016-2016 | 2011-2017 | 2011- 48-1467-SFN | San Diego Padres (MLB) ... San Antonio Missions (AA) ... Arizona Padres (Rk) |
| Mason Smith | 21 | OF | 6-2 | 195 | R | R | 1995-03-16 | Meridian,ID | AA | | 2013-2016 | 2013- 4- 118-SDN | San Antonio Missions (AA) ... Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Eduardo Solano | 19 | P | 6-3 | 203 | L | L | 1997-05-22 | San Cristobal,DR | Rk | | 2014-2017 | 2014- UDFA -SDN | Dominican Padres (Rk) |
| Yangervis Solarte | 28 | 2B | 5-11 | 220 | B | R | 1987-07-03 | Valencia,VZ | MLB | 2014-2019 | 2007-2025 | 2005- UDFA -MIN | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) |
| Carlos Sosa | 20 | 3B | 6-1 | 190 | R | R | 1995-08-07 | Santo Domingo Centro,DR | A- | | 2014-2016 | 2013- UDFA -SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Jose Sotillo | 20 | OF | 6-1 | 175 | R | R | 1996-05-13 | Tucupita,VZ | Rk | | 2014-2016 | 2013- UDFA -SDN | Arizona Padres (Rk) ... Dominican Padres (Rk) |
| Cory Spangenberg | 25 | 3B-2B | 6-0 | 195 | L | R | 1991-03-16 | Clarks Summit,PA | MLB | 2014-2022 | 2010-2022 | 2011- 1- 10-SDN | San Diego Padres (MLB) |
| River Stevens | 24 | 2B-3B | 6-0 | 185 | L | R | 1992-01-10 | Fountain Valley,CA | AAA | | 2012-2018 | 2012- 9- 285-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Will Stillman | 22 | P | 6-4 | 175 | R | R | 1993-11-02 | Matthews,NC | A | | 2013-2018 | 2016- 6- 174-SDN | Fort Wayne TinCaps (A) ... Tri-City Dust Devils (A-) |
| Dylan Stoops | 24 | P | 6-4 | 235 | L | L | 1992-01-27 | York,PA | A+ | | 2012-2016 | 2016- UDFA -SDN | Lake Elsinore Storm (A+) |
| Felix Suarez | 20 | DH | 6-0 | 180 | R | R | 1996-01-09 | Santo Domingo Centro,DR | Rk | | 2014-2016 | | Dominican Padres (Rk) |
| Jack Suwinski | 17 | CF-LF | 6-1 | 215 | L | L | 1998-07-29 | Chicago,IL | MLB | 2022-2025 | 2016-2025 | 2016- 15- 444-SDN | Arizona Padres (Rk) |
| Fernando Tatis | 17 | SS-RF | 6-3 | 217 | R | R | 1999-01-02 | San Pedro de Macoris,DR | MLB | 2019-2025 | 2016-2025 | 2015- UDFA -CHA | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| Carlos Taveras | 19 | OF | 5-11 | 165 | B | R | 1997-04-17 | Santo Domingo,DR | Rk | | 2015-2016 | 2015- UDFA -SDN | Dominican Padres (Rk) |
| Luis Tejada | 23 | 1B | 6-3 | 175 | R | R | 1992-10-12 | Constanza,DR | AA | | 2010-2017 | 2010- UDFA -SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Mason Thompson | 18 | P | 6-6 | 241 | R | R | 1998-02-20 | Round Rock,TX | MLB | 2021-2025 | 2016-2025 | 2016- 3- 85-SDN | Arizona Padres (Rk) |
| Matt Thornton | 39 | P | 6-6 | 235 | L | L | 1976-09-15 | Three Rivers,MI | MLB | 2004-2016 | 1998-2016 | 1998- 1- 22-SEA | San Diego Padres (MLB) ... Lake Elsinore Storm (A+) |
| Kodie Tidwell | 21 | IF | 6-1 | 195 | L | R | 1994-08-03 | Monroe,LA | A+ | | 2013-2016 | 2015- 26- 777-SDN | Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) ... Arizona Padres (Rk) |
| Jose Torres | 22 | P | 6-2 | 175 | L | L | 1993-09-24 | Caracas,VZ | MLB | 2016-2017 | 2011-2025 | 2010- UDFA -OAK | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Nicholas Torres | 23 | OF | 6-1 | 220 | R | R | 1993-06-30 | Long Beach,CA | AAA | | 2012-2025 | 2014- 4- 117-SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| Wilmer Torres | 20 | P | 6-3 | 190 | R | R | 1996-05-31 | Bejuma,VZ | AA | | 2015-2022 | 2015- UDFA -SDN | Arizona Padres (Rk) |
| Danny Tovar | 17 | OF | 5-11 | 180 | L | L | 1998-11-02 | Barquisimeto,VZ | Rk | | 2016-2017 | | Dominican Padres (Rk) |
| B.J. Upton | 31 | CF | 6-3 | 185 | R | R | 1984-08-21 | Norfolk,VA | MLB | 2004-2016 | 2003-2017 | 2002- 1- 2-TBA | San Diego Padres (MLB) |
| Jose Carlos Urena | 21 | OF | 6-3 | 180 | R | R | 1995-01-14 | Ciudad Obregon,MX | AAA | | 2012-2025 | 2011- UDFA -SDN | Fort Wayne TinCaps (A) |
| Luis Urias | 19 | 2B-3B | 5-9 | 202 | R | R | 1997-06-03 | Magdalena de Kino,MX | MLB | 2018-2025 | 2014-2025 | 2013- UDFA -SDN | El Paso Chihuahuas (AAA) ... Lake Elsinore Storm (A+) |
| Dauris Valdez | 20 | P | 6-8 | 254 | R | R | 1995-10-22 | Bani,DR | AAA | | 2016-2025 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Ricardo Valenzuela | 25 | C | 6-0 | 190 | R | R | 1990-08-04 | Hermosillo,MX | AAA | | 2010-2025 | 2010- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Peter Van Gansen | 22 | IF | 5-9 | 175 | L | R | 1994-03-04 | San Fernando,CA | AAA | | 2013-2019 | 2015- 12- 357-SDN | Fort Wayne TinCaps (A) |
| Josh VanMeter | 21 | 2B-LF | 5-10 | 198 | L | R | 1995-03-10 | Ossian,IN | MLB | 2019-2022 | 2013-2024 | 2013- 5- 148-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Cesar Vargas | 24 | P | 6-2 | 237 | R | R | 1991-12-30 | Puebla,MX | MLB | 2016-2016 | 2010-2025 | 2009- UDFA -NYA | San Diego Padres (MLB) ... San Antonio Missions (AA) |
| Bryan Verbitsky | 24 | P | 5-11 | 205 | R | R | 1992-06-11 | Levittown,NY | A+ | | 2011-2016 | 2013- 3- 86-SDN | Lake Elsinore Storm (A+) |
| Janigson Villalobos | 19 | C | 5-9 | 195 | R | R | 1997-05-10 | Maracaibo,VZ | Rk | | 2016-2019 | 2016- UDFA -SDN | Dominican Padres (Rk) |
| Carlos Villanueva | 32 | P | 6-2 | 220 | R | R | 1983-11-28 | Santiago,DR | MLB | 2006-2016 | 2002-2016 | 2002- UDFA -SFN | San Diego Padres (MLB) |
| Nick Vilter | 22 | 2B-3B | 6-4 | 220 | R | R | 1993-10-06 | Seal Beach,CA | AA | | 2012-2016 | 2014- 9- 267-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Brett Wallace | 29 | 1B | 6-2 | 250 | L | R | 1986-08-26 | Marin,CA | MLB | 2010-2016 | 2006-2016 | 2008- 1- 13-SLN | San Diego Padres (MLB) |
| Nelson Ward | 23 | IF | 5-11 | 175 | L | R | 1992-08-06 | Marietta,GA | AA | | 2012-2019 | 2014- 12- 351-SEA | San Antonio Missions (AA) |
| Jemile Weeks | 29 | 2B-CF | 5-9 | 170 | B | R | 1987-01-26 | Orlando,FL | MLB | 2011-2016 | 2006-2018 | 2008- 1- 12-OAK | San Diego Padres (MLB) ... El Paso Chihuahuas (AAA) ... Lake Elsinore Storm (A+) ... Arizona Padres (Rk) |
| Walker Weickel | 22 | P | 6-6 | 195 | R | R | 1993-11-14 | Orlando,FL | AA | | 2012-2022 | 2012- 1- 55-SDN | Tri-City Dust Devils (A-) ... Arizona Padres (Rk) |
| T.J. Weir | 24 | P | 6-0 | 212 | R | R | 1991-09-15 | Kokomo,IN | AAA | | 2011-2019 | 2014- 17- 507-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Boomer White | 22 | C-OF | 5-10 | 195 | R | R | 1993-07-28 | Houston,TX | A+ | | 2013-2017 | 2016- 10- 294-SDN | Tri-City Dust Devils (A-) |
| Brad Wieck | 24 | P | 6-8 | 257 | L | L | 1991-10-14 | Amarillo,TX | MLB | 2018-2021 | 2013-2024 | 2014- 7- 205-NYN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) |
| Jaquez Williams | 18 | 1B | 6-3 | 215 | L | R | 1997-11-16 | Sharpsburg,GA | Rk | | 2016-2022 | 2016- 18- 534-SDN | Arizona Padres (Rk) |
| Trey Wingenter | 22 | P | 6-7 | 237 | R | R | 1994-04-15 | Huntsville,AL | MLB | 2018-2024 | 2013-2025 | 2015- 17- 507-SDN | San Antonio Missions (AA) ... Lake Elsinore Storm (A+) ... Fort Wayne TinCaps (A) |
| Eric Yardley | 25 | P | 6-0 | 170 | R | R | 1990-08-18 | Richland,WA | MLB | 2019-2021 | 2010-2022 | 2013- UDFA -SDN | El Paso Chihuahuas (AAA) ... San Antonio Missions (AA) |
| G.K. Young | 21 | 1B | 6-1 | 225 | L | R | 1994-10-17 | Conway,SC | A | | 2014-2017 | 2016- 31- 924-SDN | Tri-City Dust Devils (A-) |
| Grant Zawadzki | 24 | IF | 5-10 | 200 | R | R | 1992-04-27 | Shrewsbury,MA | A+ | | 2014-2018 | 2016- UDFA -SDN | Arizona Padres (Rk) |
| Mark Zimmerman | 22 | P | 6-0 | 195 | L | R | 1994-03-29 | Akron,OH | A+ | | 2016-2019 | 2016- 33- 984-SDN | Lake Elsinore Storm (A+) ... Tri-City Dust Devils (A-) |
| Brad Zunica | 20 | 1B | 6-6 | 254 | L | R | 1995-10-21 | Harvey,IL | AA | | 2014-2022 | 2015- 15- 447-SDN | Fort Wayne TinCaps (A) |
| 286 record(s) |