Players who made their Major League debut during the selected season. Player must have appeared in a game as a hitter or a pitcher.
Batting and Pitching statistics for debuts are available since 1957.
| Reggie Abercrombie | 2006-04-04 | boxscore | 24.269 | OF | 6-3 | 215 | R | R | 1981-07-15 | Columbus,GA | MLB | 2006-2008 | 2000-2019 | 1999- 23- 704-LAN | premium | premium | premium |
| Winston Abreu | 2006-08-06 | boxscore | 29.130 | P | 6-2 | 170 | R | R | 1977-04-05 | Cotui,DR | MLB | 2006-2009 | 1994-2017 | 1993- UDFA -ATL | premium | premium | premium |
| Matt Albers | 2006-07-25 | boxscore | 23.192 | P | 6-1 | 225 | L | R | 1983-01-20 | Houston,TX | MLB | 2006-2019 | 2002-2019 | 2001- 23- 686-HOU | premium | premium | premium |
| Eliezer Alfonzo | 2006-06-03 | boxscore | 27.123 | 1B | 5-11 | 220 | R | R | 1979-02-07 | Puerto La Cruz,VZ | MLB | 2006-2011 | 1997-2016 | 1996- UDFA -SLN | premium | premium | premium |
| Drew T. Anderson | 2006-09-11 | boxscore | 25.100 | OF | 6-2 | 200 | L | R | 1981-06-09 | Kearney,NE | MLB | 2006-2006 | 2001-2010 | 2003- 24- 699-MIL | premium | premium | premium |
| Steve Andrade | 2006-05-01 | boxscore | 28.091 | P | 6-1 | 260 | R | R | 1978-02-06 | Woodland,CA | MLB | 2006-2006 | 2001-2009 | 2001- 32- 959-ANA | premium | premium | premium |
| Joaquin Arias | 2006-09-13 | boxscore | 21.362 | 3B | 6-1 | 185 | R | R | 1984-09-21 | Santo Domingo,DR | MLB | 2006-2015 | 2002-2015 | 2001- UDFA -NYA | premium | premium | premium |
| Erick Aybar | 2006-05-16 | boxscore | 22.128 | SS | 5-10 | 195 | B | R | 1984-01-14 | Bani,DR | MLB | 2006-2017 | 2002-2022 | 2002- UDFA -ANA | premium | premium | premium |
| Brian Bannister | 2006-04-05 | boxscore | 25.042 | P | 6-1 | 215 | R | R | 1981-02-28 | Scottsdale,AZ | MLB | 2006-2010 | 2000-2010 | 2003- 7- 199-NYN | premium | premium | premium |
| Josh Barfield | 2006-04-03 | boxscore | 23.113 | LF-RF | 6-0 | 190 | R | R | 1982-12-17 | Barquisimeto,VZ | MLB | 2006-2009 | 2001-2013 | 2001- 4- 120-SDN | premium | premium | premium |
| Chris Barnwell | 2006-06-20 | boxscore | 27.118 | IF | 5-10 | 180 | R | R | 1979-03-01 | Jacksonville,FL | MLB | 2006-2006 | 2001-2009 | 2001- 25- 748-MIL | premium | premium | premium |
| Kevin Barry | 2006-06-26 | boxscore | 27.319 | P | 6-2 | 235 | R | R | 1978-08-18 | Princeton,NJ | MLB | 2006-2007 | 1998-2007 | 2001- 14- 435-ATL | premium | premium | premium |
| Philip Barzilla | 2006-06-11 | boxscore | 27.144 | P | 6-0 | 180 | L | L | 1979-01-25 | Houston,TX | MLB | 2006-2006 | 2000-2010 | 2001- 4- 116-HOU | premium | premium | premium |
| T.J. Beam | 2006-06-17 | boxscore | 25.299 | P | 6-7 | 215 | R | R | 1980-08-28 | Scottsdale,AZ | MLB | 2006-2008 | 2002-2011 | 2003- 10- 304-NYA | premium | premium | premium |
| Chad Billingsley | 2006-06-15 | boxscore | 21.326 | P | 6-1 | 240 | R | R | 1984-07-29 | Defiance,OH | MLB | 2006-2015 | 2003-2015 | 2003- 1- 24-LAN | premium | premium | premium |
| Kurt Birkins | 2006-05-04 | boxscore | 25.272 | P | 6-2 | 190 | L | L | 1980-08-11 | West Hills,CA | MLB | 2006-2008 | 1999-2010 | 2000- 33- 984-BAL | premium | premium | premium |
| T.J. Bohn | 2006-08-22 | boxscore | 26.224 | OF | 6-5 | 200 | R | R | 1980-01-17 | St. Louis Park,MN | MLB | 2006-2008 | 2001-2011 | 2002- 30- 910-SEA | premium | premium | premium |
| Boof Bonser | 2006-05-21 | boxscore | 24.225 | P | 6-4 | 245 | R | R | 1981-10-14 | St. Petersburg,FL | MLB | 2006-2010 | 2000-2014 | 2000- 1- 21-SFN | premium | premium | premium |
| Michael Bourn | 2006-07-30 | boxscore | 23.221 | CF | 5-11 | 190 | L | R | 1982-12-27 | Houston,TX | MLB | 2006-2016 | 2001-2017 | 2003- 4- 115-PHI | premium | premium | premium |
| Ryan Braun | 2006-09-02 | boxscore | 26.041 | P | 6-1 | 220 | R | R | 1980-07-29 | Kitchener,ON | MLB | 2006-2007 | 2000-2011 | 2003- 6- 162-KCA | premium | premium | premium |
| Bill Bray | 2006-06-03 | boxscore | 22.004 | P | 6-3 | 215 | L | L | 1983-06-05 | Virginia Beach,VA | MLB | 2006-2012 | 2002-2013 | 2004- 1- 13-MON | premium | premium | premium |
| Chris Britton | 2006-04-12 | boxscore | 23.123 | P | 6-3 | 275 | R | R | 1982-12-16 | Hollywood,FL | MLB | 2006-2008 | 2001-2015 | 2001- 8- 233-BAL | premium | premium | premium |
| Andrew Brown | 2006-08-13 | boxscore | 25.183 | P | 6-6 | 230 | R | R | 1981-02-17 | Chardon,OH | MLB | 2006-2008 | 1999-2010 | 1999- 6- 204-ATL | premium | premium | premium |
| Jeremy Brown | 2006-09-03 | boxscore | 26.320 | C | 5-10 | 220 | R | R | 1979-10-25 | Birmingham,AL | MLB | 2006-2006 | 1999-2007 | 2002- 1- 35-OAK | premium | premium | premium |
| Taylor Buchholz | 2006-04-07 | boxscore | 24.182 | P | 6-3 | 220 | R | R | 1981-10-13 | Lower Merion,PA | MLB | 2006-2011 | 2000-2011 | 2000- 6- 175-PHI | premium | premium | premium |
| Brian Burres | 2006-09-08 | boxscore | 25.159 | P | 6-1 | 175 | L | L | 1981-04-08 | Oregon City,OR | MLB | 2006-2011 | 2001-2016 | 2000- 31- 931-SFN | premium | premium | premium |
| Alberto Callaspo | 2006-08-06 | boxscore | 23.115 | 3B | 5-8 | 210 | B | R | 1983-04-19 | Maracay,VZ | MLB | 2006-2015 | 2002-2022 | 2001- UDFA -ANA | premium | premium | premium |
| Brett Campbell | 2006-09-07 | boxscore | 24.331 | P | 6-0 | 170 | R | R | 1981-10-17 | Atlanta,GA | MLB | 2006-2006 | 2004-2007 | 2004- 34-1014-MON | premium | premium | premium |
| Andy Cannizaro | 2006-09-05 | boxscore | 27.267 | SS | 5-10 | 170 | R | R | 1978-12-19 | New Orleans,LA | MLB | 2006-2008 | 1998-2009 | 2001- 7- 215-NYA | premium | premium | premium |
| Alexi Casilla | 2006-09-01 | boxscore | 22.048 | 2B | 5-9 | 190 | B | R | 1984-07-20 | San Cristobal,DR | MLB | 2006-2014 | 2004-2019 | 2003- UDFA -ANA | premium | premium | premium |
| Fabio Castro | 2006-04-06 | boxscore | 21.081 | P | 5-7 | 185 | L | L | 1985-01-20 | Monte Cristi,DR | MLB | 2006-2007 | 2003-2015 | 2001- UDFA -CHA | premium | premium | premium |
| Travis Chick | 2006-09-13 | boxscore | 22.100 | P | 6-3 | 220 | R | R | 1984-06-10 | Irving,TX | MLB | 2006-2006 | 2002-2010 | 2002- 14- 413-MIA | premium | premium | premium |
| Jason Childers | 2006-04-03 | boxscore | 31.088 | P | 6-2 | 190 | R | R | 1975-01-13 | Statesboro,GA | MLB | 2006-2006 | 1997-2010 | 1987- UDFA -MIL | premium | premium | premium |
| Brent Clevlen | 2006-07-30 | boxscore | 22.282 | OF | 6-1 | 205 | R | R | 1983-10-27 | Austin,TX | MLB | 2006-2010 | 2002-2017 | 2002- 2- 49-DET | premium | premium | premium |
| Buck Coats | 2006-08-22 | boxscore | 24.080 | RF | 6-3 | 200 | L | R | 1982-06-09 | Fort Benning,GA | MLB | 2006-2008 | 2000-2011 | 2000- 18- 523-CHN | premium | premium | premium |
| Alvin Colina | 2006-09-18 | boxscore | 24.272 | C | 6-3 | 210 | R | R | 1981-12-26 | Puerto Cabello,VZ | MLB | 2006-2006 | 2000-2013 | 1998- UDFA -COL | premium | premium | premium |
| Manny Corpas | 2006-07-18 | boxscore | 23.233 | P | 6-3 | 170 | R | R | 1982-12-03 | Panama City,PN | MLB | 2006-2013 | 2002-2025 | 1999- UDFA -COL | premium | premium | premium |
| Chris Coste | 2006-05-26 | boxscore | 33.119 | C | 6-1 | 210 | R | R | 1973-02-04 | Fargo,ND | MLB | 2006-2009 | 1995-2009 | 1999- UDFA -CLE | premium | premium | premium |
| Rajai Davis | 2006-08-14 | boxscore | 25.305 | LF-RF | 5-10 | 195 | R | R | 1980-10-19 | Norwich,CT | MLB | 2006-2019 | 2001-2019 | 2001- 38-1134-PIT | premium | premium | premium |
| Yurendell Decaster | 2006-05-21 | boxscore | 26.244 | IF | 6-0 | 215 | R | R | 1979-09-26 | Willemstad,CC | MLB | 2006-2006 | 1998-2015 | 1996- UDFA -TBA | premium | premium | premium |
| Joselo Diaz | 2006-09-06 | boxscore | 26.152 | P | 6-0 | 230 | R | R | 1980-04-13 | San Pedro de Macoris,DR | MLB | 2006-2008 | 1997-2011 | 2006- UDFA -LAN | premium | premium | premium |
| Melvin Dorta | 2006-07-21 | boxscore | 24.193 | IF | 5-11 | 160 | R | R | 1982-01-15 | Valencia,VZ | MLB | 2006-2006 | 2001-2011 | 1998- UDFA -BOS | premium | premium | premium |
| Stephen Drew | 2006-07-15 | boxscore | 23.127 | SS | 6-0 | 200 | L | R | 1983-03-16 | Hahira,GA | MLB | 2006-2017 | 2005-2017 | 2004- 1- 15-ARI | premium | premium | premium |
| Andre Ethier | 2006-05-02 | boxscore | 24.028 | CF-RF | 6-2 | 210 | L | L | 1982-04-10 | Phoenix,AZ | MLB | 2006-2017 | 2002-2017 | 2003- 2- 62-OAK | premium | premium | premium |
| Willie Eyre | 2006-04-06 | boxscore | 27.266 | P | 6-0 | 235 | R | R | 1978-07-21 | Fountain Valley,CA | MLB | 2006-2011 | 1999-2012 | 1999- 23- 689-MIN | premium | premium | premium |
| Brandon Fahey | 2006-04-30 | boxscore | 25.108 | SS-3B | 6-1 | 160 | L | R | 1981-01-18 | Dallas,TX | MLB | 2006-2008 | 2002-2008 | 2002- 12- 346-BAL | premium | premium | premium |
| Ryan Feierabend | 2006-09-13 | boxscore | 21.027 | P | 6-3 | 225 | L | L | 1985-08-22 | Cleveland,OH | MLB | 2006-2019 | 2003-2021 | 2003- 3- 86-SEA | premium | premium | premium |
| Josh Fields | 2006-09-13 | boxscore | 23.279 | 1B | 6-2 | 225 | R | R | 1982-12-14 | Ada,OK | MLB | 2006-2010 | 2002-2015 | 2004- 1- 18-CHA | premium | premium | premium |
| Kevin Frandsen | 2006-04-28 | boxscore | 23.345 | 1B | 6-0 | 190 | R | R | 1982-05-24 | Los Gatos,CA | MLB | 2006-2015 | 2001-2015 | 2004- 12- 370-SFN | premium | premium | premium |
| Emiliano Fruto | 2006-05-14 | boxscore | 21.347 | P | 6-3 | 230 | R | R | 1984-06-06 | Bolivar,CB | MLB | 2006-2006 | 2001-2014 | 2000- UDFA -SEA | premium | premium | premium |
| Jeff Fulchino | 2006-06-22 | boxscore | 26.215 | P | 6-4 | 270 | R | R | 1979-11-26 | Titusville,FL | MLB | 2006-2011 | 2001-2013 | 2001- 8- 242-MIA | premium | premium | premium |
| Kason Gabbard | 2006-07-22 | boxscore | 24.111 | P | 6-3 | 200 | L | L | 1982-04-08 | Oxford,OH | MLB | 2006-2008 | 2001-2010 | 2000- 29- 872-BOS | premium | premium | premium |
| Jose Garcia | 2006-09-11 | boxscore | 21.252 | P | 5-11 | 165 | R | R | 1985-01-07 | Dajabon,DR | MLB | 2006-2006 | 2005-2009 | 2001- UDFA -MIA | premium | premium | premium |
| Matt Garza | 2006-08-11 | boxscore | 22.264 | P | 6-4 | 220 | R | R | 1983-11-26 | Selma,CA | MLB | 2006-2017 | 2003-2017 | 2005- 1- 25-MIN | premium | premium | premium |
| Hector Gimenez | 2006-09-25 | boxscore | 23.003 | C | 5-10 | 230 | B | R | 1982-09-28 | San Felipe,VZ | MLB | 2006-2013 | 2002-2016 | 1999- UDFA -HOU | premium | premium | premium |
| Enrique Gonzalez | 2006-05-28 | boxscore | 23.324 | P | 5-10 | 225 | R | R | 1982-07-14 | Bolivar,VZ | MLB | 2006-2011 | 2000-2013 | 1998- UDFA -ARI | premium | premium | premium |
| Sean Green | 2006-05-02 | boxscore | 27.019 | P | 6-6 | 230 | R | R | 1979-04-20 | Louisville,KY | MLB | 2006-2011 | 1998-2012 | 2000- 12- 347-COL | premium | premium | premium |
| Angel Guzman | 2006-04-26 | boxscore | 24.139 | P | 6-3 | 190 | R | R | 1981-12-14 | Caracas,VZ | MLB | 2006-2009 | 2001-2012 | 1999- UDFA -CHN | premium | premium | premium |
| Joel Guzman | 2006-06-01 | boxscore | 21.194 | 1B | 6-7 | 225 | R | R | 1984-11-24 | Ingenio Quisqueya,DR | MLB | 2006-2007 | 2002-2017 | 2001- UDFA -LAN | premium | premium | premium |
| Tony Gwynn | 2006-07-15 | boxscore | 23.290 | OF | 6-0 | 190 | L | R | 1982-10-04 | Long Beach,CA | MLB | 2006-2014 | 2001-2015 | 2003- 2- 39-MIL | premium | premium | premium |
| Charlie Haeger | 2006-05-10 | boxscore | 22.239 | P | 6-1 | 210 | R | R | 1983-09-19 | Livonia,MI | MLB | 2006-2010 | 2001-2013 | 2001- 25- 763-CHA | premium | premium | premium |
| Cole Hamels | 2006-05-12 | boxscore | 22.142 | P | 6-4 | 205 | L | L | 1983-12-27 | San Diego,CA | MLB | 2006-2020 | 2003-2020 | 2002- 1- 17-PHI | premium | premium | premium |
| Jason Hammel | 2006-04-11 | boxscore | 23.227 | P | 6-6 | 225 | R | R | 1982-09-02 | Greenville,SC | MLB | 2006-2018 | 2002-2018 | 2002- 10- 284-TBA | premium | premium | premium |
| Justin Hampson | 2006-09-10 | boxscore | 26.115 | P | 6-1 | 205 | L | L | 1980-05-24 | Belleville,IL | MLB | 2006-2012 | 2000-2013 | 1999- 28- 850-COL | premium | premium | premium |
| Jack Hannahan | 2006-05-25 | boxscore | 26.088 | 3B | 6-2 | 210 | L | R | 1980-03-04 | St. Paul,MN | MLB | 2006-2014 | 2000-2014 | 2001- 3- 87-DET | premium | premium | premium |
| Devern Hansack | 2006-09-23 | boxscore | 28.237 | P | 6-2 | 180 | R | R | 1978-02-05 | Pearl Lagoon,NI | MLB | 2006-2008 | 2002-2009 | 2005- UDFA -HOU | premium | premium | premium |
| Brandon Harper | 2006-08-09 | boxscore | 30.109 | C | 6-4 | 200 | R | R | 1976-04-29 | Odessa,TX | MLB | 2006-2006 | 1997-2007 | 1997- 4- 126-MIA | premium | premium | premium |
| John Hattig | 2006-08-19 | boxscore | 26.180 | 3B | 6-2 | 215 | B | R | 1980-02-27 | Tamuning,GU | MLB | 2006-2006 | 1999-2008 | 1998- 25- 745-BOS | premium | premium | premium |
| Roberto Hernandez | 2006-04-15 | boxscore | 25.234 | P | 6-4 | 270 | R | R | 1980-08-30 | Santo Domingo,DR | MLB | 2006-2016 | 2002-2016 | 2000- UDFA -CLE | premium | premium | premium |
| Jason Hirsh | 2006-08-12 | boxscore | 24.179 | P | 6-8 | 250 | R | R | 1982-02-20 | Burbank,CA | MLB | 2006-2008 | 2003-2013 | 2003- 2- 59-HOU | premium | premium | premium |
| Jim Hoey | 2006-08-23 | boxscore | 23.242 | P | 6-6 | 205 | R | R | 1982-12-30 | Trenton,NJ | MLB | 2006-2011 | 2001-2013 | 2003- 13- 374-BAL | premium | premium | premium |
| Norris Hopper | 2006-08-20 | boxscore | 27.156 | OF | 5-11 | 205 | R | R | 1979-03-24 | Shelby,NC | MLB | 2006-2008 | 1998-2012 | 1998- 8- 227-KCA | premium | premium | premium |
| Jon Huber | 2006-08-30 | boxscore | 25.060 | P | 6-1 | 200 | R | R | 1981-07-07 | Sacramento,CA | MLB | 2006-2007 | 2000-2011 | 2000- 5- 139-SDN | premium | premium | premium |
| Philip Humber | 2006-09-24 | boxscore | 23.283 | P | 6-3 | 215 | R | R | 1982-12-21 | Nacogdoches,TX | MLB | 2006-2013 | 2002-2014 | 2004- 1- 3-NYN | premium | premium | premium |
| Chris Iannetta | 2006-08-27 | boxscore | 23.147 | C | 6-0 | 230 | R | R | 1983-04-08 | Providence,RI | MLB | 2006-2019 | 2002-2019 | 2004- 4- 110-COL | premium | premium | premium |
| Joe Inglett | 2006-06-21 | boxscore | 27.364 | 2B-LF | 5-9 | 175 | L | R | 1978-06-29 | Sacramento,CA | MLB | 2006-2011 | 1997-2011 | 2000- 8- 246-CLE | premium | premium | premium |
| Travis Ishikawa | 2006-04-18 | boxscore | 22.212 | 1B | 6-3 | 220 | L | L | 1983-09-24 | Seattle,WA | MLB | 2006-2015 | 2002-2016 | 2002- 21- 637-SFN | premium | premium | premium |
| Zach Jackson | 2006-06-04 | boxscore | 23.028 | P | 6-5 | 220 | L | L | 1983-05-13 | Latrobe,PA | MLB | 2006-2009 | 2002-2015 | 2004- 1- 32-TOR | premium | premium | premium |
| Casey Janssen | 2006-04-27 | boxscore | 24.228 | P | 6-4 | 210 | R | R | 1981-09-17 | Orange,CA | MLB | 2006-2015 | 2001-2017 | 2004- 4- 117-TOR | premium | premium | premium |
| Cesar Jimenez | 2006-09-11 | boxscore | 21.308 | P | 6-0 | 215 | L | L | 1984-11-12 | Cumana,VZ | MLB | 2006-2015 | 2002-2019 | 2001- UDFA -SEA | premium | premium | premium |
| Ubaldo Jimenez | 2006-09-26 | boxscore | 22.253 | P | 6-5 | 221 | R | R | 1984-01-22 | Nagua,DR | MLB | 2006-2017 | 2002-2017 | 2001- UDFA -COL | premium | premium | premium |
| Kenji Johjima | 2006-04-03 | boxscore | 29.306 | C | 6-0 | 205 | R | R | 1976-06-08 | Sasebo,JP | MLB | 2006-2009 | 1995-2012 | 2005- UDFA -SEA | premium | premium | premium |
| Jim Johnson | 2006-07-29 | boxscore | 23.038 | P | 6-6 | 250 | R | R | 1983-06-27 | Johnson City,NY | MLB | 2006-2018 | 2001-2018 | 2001- 5- 143-BAL | premium | premium | premium |
| Adam Jones | 2006-07-14 | boxscore | 20.352 | CF | 6-2 | 215 | R | R | 1985-08-01 | San Diego,CA | MLB | 2006-2019 | 2003-2021 | 2003- 1- 37-SEA | premium | premium | premium |
| Jeff Karstens | 2006-08-22 | boxscore | 23.338 | P | 6-3 | 185 | R | R | 1982-09-24 | San Diego,CA | MLB | 2006-2012 | 2003-2013 | 2003- 19- 574-NYA | premium | premium | premium |
| Matt Kemp | 2006-05-28 | boxscore | 21.252 | CF | 6-4 | 225 | R | R | 1984-09-23 | Midwest City,OK | MLB | 2006-2020 | 2003-2020 | 2003- 6- 181-LAN | premium | premium | premium |
| Howie Kendrick | 2006-04-26 | boxscore | 22.294 | 2B | 5-11 | 225 | R | R | 1983-07-12 | Jacksonville,FL | MLB | 2006-2020 | 2002-2020 | 2002- 10- 294-ANA | premium | premium | premium |
| Bob Keppel | 2006-05-25 | boxscore | 23.354 | P | 6-5 | 215 | R | R | 1982-06-11 | St. Louis,MO | MLB | 2006-2009 | 2000-2013 | 2000- 1- 36-NYN | premium | premium | premium |
| Josh Kinney | 2006-07-03 | boxscore | 27.101 | P | 6-0 | 220 | R | R | 1979-03-31 | Coudersport,PA | MLB | 2006-2012 | 2001-2014 | 2001- UDFA -SLN | premium | premium | premium |
| Ian Kinsler | 2006-04-03 | boxscore | 23.291 | 2B | 6-0 | 200 | R | R | 1982-06-22 | Tucson,AZ | MLB | 2006-2019 | 2002-2021 | 2003- 17- 496-TEX | premium | premium | premium |
| Shane Komine | 2006-07-30 | boxscore | 25.291 | P | 5-9 | 180 | R | R | 1980-10-18 | Honolulu,HI | MLB | 2006-2007 | 1999-2009 | 2002- 9- 278-OAK | premium | premium | premium |
| Kevin Kouzmanoff | 2006-09-02 | boxscore | 25.045 | 3B | 6-1 | 210 | R | R | 1981-07-25 | Newport Beach,CA | MLB | 2006-2014 | 2002-2014 | 2003- 6- 168-CLE | premium | premium | premium |
| Juan Lara | 2006-09-08 | boxscore | 25.231 | P | 6-2 | 190 | R | L | 1981-01-26 | Azua,DR | MLB | 2006-2007 | 2002-2009 | 1999- UDFA -CLE | premium | premium | premium |
| Jon Lester | 2006-06-10 | boxscore | 22.160 | P | 6-4 | 249 | L | L | 1984-01-07 | Tacoma,WA | MLB | 2006-2021 | 2002-2021 | 2002- 2- 57-BOS | premium | premium | premium |
| Fred Lewis | 2006-09-01 | boxscore | 25.272 | LF | 6-2 | 205 | L | R | 1980-12-09 | Hattiesburg,MS | MLB | 2006-2012 | 2002-2016 | 2002- 2- 66-SFN | premium | premium | premium |
| Adam Lind | 2006-09-02 | boxscore | 23.053 | 1B-DH | 6-2 | 195 | L | L | 1983-07-17 | Muncie,IN | MLB | 2006-2017 | 2003-2018 | 2004- 3- 83-TOR | premium | premium | premium |
| Wes Littleton | 2006-07-04 | boxscore | 23.311 | P | 6-3 | 200 | R | R | 1982-09-02 | Hayward,CA | MLB | 2006-2008 | 2001-2012 | 2003- 4- 106-TEX | premium | premium | premium |
| Bobby Livingston | 2006-04-25 | boxscore | 23.240 | P | 6-3 | 205 | L | L | 1982-09-03 | St. Louis,MO | MLB | 2006-2007 | 2002-2013 | 2001- 4- 129-SEA | premium | premium | premium |
| Adam Loewen | 2006-05-23 | boxscore | 22.049 | P | 6-6 | 245 | L | L | 1984-04-09 | Vancouver,BC | MLB | 2006-2016 | 2003-2018 | 2002- 1- 4-BAL | premium | premium | premium |
| Boone Logan | 2006-04-04 | boxscore | 21.239 | P | 6-5 | 215 | R | L | 1984-08-13 | San Antonio,TX | MLB | 2006-2018 | 2003-2018 | 2002- 20- 600-CHA | premium | premium | premium |
| James Loney | 2006-04-04 | boxscore | 21.337 | 1B | 6-3 | 235 | L | L | 1984-05-07 | Houston,TX | MLB | 2006-2016 | 2002-2019 | 2002- 1- 19-LAN | premium | premium | premium |
| Mark Lowe | 2006-07-07 | boxscore | 23.036 | P | 6-3 | 210 | L | R | 1983-06-07 | Houston,TX | MLB | 2006-2016 | 2002-2019 | 2004- 5- 153-SEA | premium | premium | premium |
| Ruddy Lugo | 2006-04-03 | boxscore | 25.322 | P | 6-0 | 210 | B | R | 1980-05-22 | Barahona,DR | MLB | 2006-2007 | 1999-2013 | 1999- 3- 94-MIL | premium | premium | premium |
| Chris Mabeus | 2006-05-29 | boxscore | 27.114 | P | 6-3 | 235 | R | R | 1979-02-11 | Peoria,IL | MLB | 2006-2006 | 2001-2006 | 2001- 13- 401-OAK | premium | premium | premium |
| Mitch Maier | 2006-09-23 | boxscore | 24.091 | OF | 6-3 | 210 | L | R | 1982-06-30 | Petoskey,MI | MLB | 2006-2012 | 2001-2014 | 2003- 1- 30-KCA | premium | premium | premium |
| Carlos Maldonado | 2006-09-08 | boxscore | 27.255 | C | 6-2 | 260 | R | R | 1979-01-03 | Maracaibo,VZ | MLB | 2006-2012 | 1996-2013 | 1995- UDFA -SEA | premium | premium | premium |
| Nick Markakis | 2006-04-03 | boxscore | 22.143 | RF | 6-1 | 210 | L | L | 1983-11-17 | Woodstock,GA | MLB | 2006-2020 | 2003-2020 | 2003- 1- 7-BAL | premium | premium | premium |
| Carlos Marmol | 2006-06-04 | boxscore | 23.239 | P | 6-1 | 235 | R | R | 1982-10-14 | Bonao,DR | MLB | 2006-2014 | 2001-2015 | 1999- UDFA -CHN | premium | premium | premium |
| Sean Marshall | 2006-04-09 | boxscore | 23.228 | P | 6-7 | 225 | L | L | 1982-08-30 | Richmond,VA | MLB | 2006-2014 | 2001-2014 | 2003- 6- 163-CHN | premium | premium | premium |
| Russell Martin | 2006-05-05 | boxscore | 23.085 | C | 5-10 | 215 | R | R | 1983-02-15 | East York,ON | MLB | 2006-2019 | 2002-2019 | 2002- 17- 511-LAN | premium | premium | premium |
| Carlos Martinez | 2006-04-03 | boxscore | 23.318 | P | 6-2 | 220 | R | R | 1982-05-26 | Villa Vasquez,DR | MLB | 2006-2009 | 2003-2009 | 2000- UDFA -MIA | premium | premium | premium |
| Nick Masset | 2006-06-27 | boxscore | 24.047 | P | 6-5 | 225 | R | R | 1982-05-17 | St. Petersburg,FL | MLB | 2006-2015 | 2001-2016 | 2000- 8- 244-TEX | premium | premium | premium |
| Tom Mastny | 2006-07-30 | boxscore | 25.182 | P | 6-6 | 225 | R | R | 1981-02-04 | East Bontang,IO | MLB | 2006-2008 | 2000-2010 | 2003- 11- 320-TOR | premium | premium | premium |
| Juan Mateo | 2006-08-03 | boxscore | 23.235 | P | 6-2 | 235 | R | R | 1982-12-17 | Bani,DR | MLB | 2006-2006 | 2003-2011 | 2001- UDFA -CHN | premium | premium | premium |
| Scott Mathieson | 2006-06-17 | boxscore | 22.116 | P | 6-3 | 230 | R | R | 1984-02-27 | Vancouver,BC | MLB | 2006-2011 | 2002-2019 | 2002- 17- 509-PHI | premium | premium | premium |
| Drew Meyer | 2006-04-21 | boxscore | 24.241 | SS | 5-10 | 205 | L | R | 1981-08-29 | Charleston,SC | MLB | 2006-2006 | 2000-2010 | 2002- 1- 10-TEX | premium | premium | premium |
| Lastings Milledge | 2006-05-30 | boxscore | 21.060 | LF-RF | 5-11 | 210 | R | R | 1985-04-05 | Bradenton,FL | MLB | 2006-2011 | 2003-2017 | 2003- 1- 12-NYN | premium | premium | premium |
| Andrew Miller | 2006-08-30 | boxscore | 21.106 | P | 6-7 | 200 | L | L | 1985-05-21 | Gainesville,FL | MLB | 2006-2021 | 2004-2021 | 2006- 1- 6-DET | premium | premium | premium |
| Zach Miner | 2006-06-04 | boxscore | 24.090 | P | 6-4 | 225 | R | R | 1982-03-12 | St. Louis,MO | MLB | 2006-2013 | 2001-2014 | 2000- 4- 106-ATL | premium | premium | premium |
| Pat Misch | 2006-09-21 | boxscore | 25.040 | P | 6-2 | 195 | R | L | 1981-08-18 | Northbrook,IL | MLB | 2006-2011 | 2000-2017 | 2003- 7- 213-SFN | premium | premium | premium |
| Agustin Montero | 2006-05-12 | boxscore | 28.266 | P | 6-3 | 210 | R | R | 1977-08-26 | San Pedro de Macoris,DR | MLB | 2006-2006 | 1997-2008 | 1995- UDFA -OAK | premium | premium | premium |
| Miguel Montero | 2006-09-06 | boxscore | 23.065 | C | 5-11 | 221 | L | R | 1983-07-09 | Caracas,VZ | MLB | 2006-2018 | 2002-2018 | 2001- UDFA -ARI | premium | premium | premium |
| Scott Moore | 2006-09-04 | boxscore | 22.297 | 3B | 6-2 | 195 | L | R | 1983-11-17 | Long Beach,CA | MLB | 2006-2012 | 2002-2015 | 2002- 1- 8-DET | premium | premium | premium |
| Kendrys Morales | 2006-05-23 | boxscore | 22.343 | DH | 6-1 | 242 | B | R | 1983-06-20 | Fomento,CU | MLB | 2006-2019 | 2002-2019 | 2014- UDFA -ANA | premium | premium | premium |
| Juan Morillo | 2006-09-24 | boxscore | 22.329 | P | 6-3 | 190 | R | R | 1983-11-05 | San Pedro de Macoris,DR | MLB | 2006-2025 | 2003-2025 | 2001- UDFA -COL | premium | premium | premium |
| Dustin Moseley | 2006-07-17 | boxscore | 24.209 | P | 6-4 | 215 | R | R | 1981-12-26 | Texarkana,TX | MLB | 2006-2012 | 2001-2014 | 2000- 1- 34-CIN | premium | premium | premium |
| Peter Moylan | 2006-04-12 | boxscore | 27.138 | P | 6-3 | 220 | R | R | 1978-12-02 | Lesmurdie,AU | MLB | 2006-2018 | 1996-2018 | 1996- UDFA -MIN | premium | premium | premium |
| Edward Mujica | 2006-06-21 | boxscore | 22.047 | P | 6-3 | 220 | R | R | 1984-05-10 | Valencia,VZ | MLB | 2006-2017 | 2003-2018 | 2001- UDFA -CLE | premium | premium | premium |
| David Murphy | 2006-09-02 | boxscore | 24.325 | LF | 6-3 | 210 | L | L | 1981-10-18 | Houston,TX | MLB | 2006-2015 | 2001-2016 | 2003- 1- 17-BOS | premium | premium | premium |
| Tommy Murphy | 2006-05-04 | boxscore | 26.257 | SS | 5-11 | 200 | B | R | 1979-08-27 | Suffern,NY | MLB | 2006-2007 | 1998-2009 | 2000- 3- 80-ANA | premium | premium | premium |
| Mike Napoli | 2006-05-04 | boxscore | 24.191 | 1B | 6-1 | 225 | R | R | 1981-10-31 | Hollywood,FL | MLB | 2006-2017 | 2000-2018 | 2000- 17- 500-ANA | premium | premium | premium |
| Chris Narveson | 2006-09-08 | boxscore | 24.268 | P | 6-3 | 205 | L | L | 1981-12-20 | Englewood,CO | MLB | 2006-2016 | 2000-2017 | 2000- 2- 53-SLN | premium | premium | premium |
| Oswaldo Navarro | 2006-09-09 | boxscore | 21.347 | SS-3B | 6-0 | 200 | R | R | 1984-10-02 | Villa de Cura,VZ | MLB | 2006-2010 | 2003-2012 | 2001- UDFA -SEA | premium | premium | premium |
| John Nelson | 2006-09-07 | boxscore | 27.195 | SS | 6-1 | 190 | R | R | 1979-03-03 | Denton,TX | MLB | 2006-2006 | 1998-2008 | 2001- 8- 254-SLN | premium | premium | premium |
| Pat Neshek | 2006-07-07 | boxscore | 25.312 | P | 6-3 | 220 | B | R | 1980-09-04 | Madison,WI | MLB | 2006-2019 | 2000-2019 | 2002- 6- 182-MIN | premium | premium | premium |
| Fernando Nieve | 2006-04-04 | boxscore | 23.269 | P | 6-0 | 220 | R | R | 1982-07-15 | Puerto Cabello,VZ | MLB | 2006-2010 | 2001-2018 | 1999- UDFA -HOU | premium | premium | premium |
| Ricky Nolasco | 2006-04-05 | boxscore | 23.119 | P | 6-2 | 235 | R | R | 1982-12-13 | Corona,CA | MLB | 2006-2017 | 2001-2019 | 2001- 4- 108-CHN | premium | premium | premium |
| Michael O'Connor | 2006-04-27 | boxscore | 25.259 | P | 6-3 | 185 | L | L | 1980-08-17 | Dallas,TX | MLB | 2006-2011 | 1999-2013 | 2002- 7- 197-MON | premium | premium | premium |
| Eric O'Flaherty | 2006-08-16 | boxscore | 21.197 | P | 6-2 | 210 | L | L | 1985-02-05 | Walla Walla,WA | MLB | 2006-2017 | 2003-2017 | 2003- 6- 176-SEA | premium | premium | premium |
| Ryan O'Malley | 2006-08-16 | boxscore | 26.135 | P | 6-1 | 205 | R | L | 1980-04-09 | Springfield,IL | MLB | 2006-2006 | 2001-2008 | 2002- UDFA -CHN | premium | premium | premium |
| Henry Owens | 2006-07-07 | boxscore | 27.082 | P | 6-2 | 220 | R | R | 1979-04-23 | Miami,FL | MLB | 2006-2007 | 2001-2009 | 2001- UDFA -PIT | premium | premium | premium |
| Jerry Owens | 2006-09-11 | boxscore | 25.213 | OF | 6-3 | 195 | L | L | 1981-02-16 | Hollywood,CA | MLB | 2006-2009 | 2003-2016 | 2003- 2- 57-MON | premium | premium | premium |
| Angel Pagan | 2006-04-03 | boxscore | 24.281 | CF | 6-2 | 200 | B | R | 1981-07-02 | Rio Piedras,PR | MLB | 2006-2016 | 2000-2016 | 1999- 4- 136-NYN | premium | premium | premium |
| David Pauley | 2006-05-31 | boxscore | 22.354 | P | 6-2 | 215 | R | R | 1983-06-17 | Longmont,CO | MLB | 2006-2012 | 2001-2014 | 2001- 8- 240-SDN | premium | premium | premium |
| Dustin Pedroia | 2006-08-22 | boxscore | 23.011 | 2B | 5-9 | 170 | R | R | 1983-08-17 | Woodland,CA | MLB | 2006-2019 | 2002-2019 | 2004- 2- 65-BOS | premium | premium | premium |
| Mike Pelfrey | 2006-07-08 | boxscore | 22.181 | P | 6-7 | 240 | R | R | 1984-01-14 | Wichita,KS | MLB | 2006-2017 | 2003-2017 | 2005- 1- 9-NYN | premium | premium | premium |
| Tony Pena | 2006-04-13 | boxscore | 25.027 | P | 6-2 | 180 | R | R | 1981-03-23 | Santiago,DR | MLB | 2006-2009 | 2000-2017 | 1999- UDFA -ATL | premium | premium | premium |
| Tony Pena | 2006-07-18 | boxscore | 24.196 | P | 6-2 | 240 | R | R | 1982-01-09 | Santo Domingo,DR | MLB | 2006-2011 | 2004-2016 | 2002- UDFA -ARI | premium | premium | premium |
| Beltran Perez | 2006-09-02 | boxscore | 24.319 | P | 6-2 | 180 | R | R | 1981-10-24 | San Francisco de Macoris,DR | MLB | 2006-2006 | 2000-2008 | 1999- UDFA -ARI | premium | premium | premium |
| Juan Pablo Perez | 2006-09-07 | boxscore | 28.011 | P | 6-0 | 190 | R | L | 1978-09-03 | Villa Rivas,DR | MLB | 2006-2013 | 2002-2016 | 1998- UDFA -BOS | premium | premium | premium |
| Rafael Perez | 2006-04-20 | boxscore | 23.346 | P | 6-3 | 195 | L | L | 1982-05-15 | Santo Domingo,DR | MLB | 2006-2012 | 2003-2017 | 2002- UDFA -CLE | premium | premium | premium |
| Glen Perkins | 2006-09-21 | boxscore | 23.209 | P | 6-0 | 205 | L | L | 1983-03-02 | St. Paul,MN | MLB | 2006-2017 | 2003-2017 | 2004- 1- 22-MIN | premium | premium | premium |
| Yusmeiro Petit | 2006-05-14 | boxscore | 21.178 | P | 6-1 | 252 | R | R | 1984-11-22 | Maracaibo,VZ | MLB | 2006-2021 | 2003-2022 | 2001- UDFA -NYN | premium | premium | premium |
| Renyel Pinto | 2006-05-18 | boxscore | 23.320 | P | 6-4 | 280 | L | L | 1982-07-08 | Miranda,VZ | MLB | 2006-2010 | 2000-2022 | 1999- UDFA -CHN | premium | premium | premium |
| Martin Prado | 2006-04-23 | boxscore | 22.184 | 3B | 6-0 | 215 | R | R | 1983-10-27 | Maracay,VZ | MLB | 2006-2019 | 2003-2019 | 2001- UDFA -ATL | premium | premium | premium |
| Carlos Quentin | 2006-07-20 | boxscore | 23.332 | LF | 6-1 | 235 | R | R | 1982-08-28 | Bellflower,CA | MLB | 2006-2014 | 2001-2017 | 2003- 1- 29-ARI | premium | premium | premium |
| Josh Rabe | 2006-07-17 | boxscore | 27.282 | OF | 6-3 | 215 | R | R | 1978-10-15 | Quincy,IL | MLB | 2006-2007 | 2000-2008 | 2000- 11- 312-MIN | premium | premium | premium |
| Mike Rabelo | 2006-09-23 | boxscore | 26.256 | C | 6-1 | 200 | B | R | 1980-01-17 | New Port Richey,FL | MLB | 2006-2008 | 1999-2010 | 2001- 4- 117-DET | premium | premium | premium |
| Ramon Ramirez | 2006-04-14 | boxscore | 24.232 | P | 5-11 | 200 | R | R | 1981-08-31 | Santiago,DR | MLB | 2006-2014 | 2002-2022 | 1996- UDFA -TEX | premium | premium | premium |
| Santiago Ramirez | 2006-05-24 | boxscore | 27.289 | P | 5-11 | 210 | R | R | 1978-08-15 | Bonao,DR | MLB | 2006-2006 | 1999-2009 | 1997- UDFA -HOU | premium | premium | premium |
| Eric Reed | 2006-04-03 | boxscore | 25.128 | OF | 6-0 | 170 | L | L | 1980-12-02 | Little Rock,AR | MLB | 2006-2007 | 2000-2008 | 2002- 9- 263-MIA | premium | premium | premium |
| Jose Reyes | 2006-09-13 | boxscore | 22.205 | C | 6-0 | 225 | B | R | 1984-02-26 | Barahona,DR | MLB | 2006-2006 | 2002-2007 | 1999- UDFA -CHN | premium | premium | premium |
| John Rheinecker | 2006-04-22 | boxscore | 26.335 | P | 6-2 | 220 | L | L | 1979-05-29 | Belleville,IL | MLB | 2006-2007 | 2000-2008 | 2001- 1- 37-OAK | premium | premium | premium |
| Shawn Riggans | 2006-09-05 | boxscore | 26.048 | C | 6-2 | 200 | R | R | 1980-07-25 | Fort Lauderdale,FL | MLB | 2006-2009 | 2001-2011 | 2000- 24- 706-TBA | premium | premium | premium |
| Saul Rivera | 2006-05-25 | boxscore | 28.176 | P | 5-10 | 180 | B | R | 1977-12-07 | San Juan,PR | MLB | 2006-2010 | 1997-2012 | 1998- 9- 259-MIN | premium | premium | premium |
| Sendy Rleal | 2006-04-05 | boxscore | 25.294 | P | 6-1 | 190 | R | R | 1980-06-21 | San Pedro De Macoris,DR | MLB | 2006-2006 | 2000-2011 | 1999- UDFA -BAL | premium | premium | premium |
| Chris Roberson | 2006-05-12 | boxscore | 26.269 | OF | 6-2 | 180 | B | R | 1979-08-23 | Oakland,CA | MLB | 2006-2007 | 2001-2023 | 2001- 9- 260-PHI | premium | premium | premium |
| Ryan Roberts | 2006-07-30 | boxscore | 25.320 | 2B | 5-11 | 185 | R | R | 1980-09-19 | Fort Worth,TX | MLB | 2006-2014 | 2002-2015 | 2003- 18- 530-TOR | premium | premium | premium |
| Brian Rogers | 2006-09-01 | boxscore | 24.052 | P | 6-4 | 190 | R | R | 1982-07-17 | Dallas,TX | MLB | 2006-2007 | 2001-2008 | 2003- 11- 310-DET | premium | premium | premium |
| Davis Romero | 2006-08-18 | boxscore | 23.147 | P | 5-10 | 185 | L | L | 1983-03-30 | Aguadulce,PN | MLB | 2006-2006 | 2002-2009 | 1999- UDFA -TOR | premium | premium | premium |
| Francisco Rosario | 2006-05-06 | boxscore | 25.226 | P | 6-1 | 225 | R | R | 1980-09-28 | San Rafael del Yuma,DR | MLB | 2006-2007 | 2001-2019 | 1999- UDFA -TOR | premium | premium | premium |
| Vinny Rottino | 2006-09-01 | boxscore | 26.153 | LF-RF | 6-1 | 215 | R | R | 1980-04-07 | Racine,WI | MLB | 2006-2012 | 2003-2016 | 2003- UDFA -MIL | premium | premium | premium |
| Mike Rouse | 2006-06-09 | boxscore | 26.051 | SS | 6-0 | 190 | L | R | 1980-04-25 | San Jose,CA | MLB | 2006-2007 | 1999-2008 | 2001- 5- 151-TOR | premium | premium | premium |
| Carlos Ruiz | 2006-05-06 | boxscore | 27.111 | C | 5-10 | 215 | R | R | 1979-01-22 | David,PN | MLB | 2006-2017 | 2000-2017 | 1998- UDFA -PHI | premium | premium | premium |
| Jae Kuk Ryu | 2006-05-14 | boxscore | 22.355 | P | 6-3 | 225 | R | R | 1983-05-30 | Choon Chung Do,KR | MLB | 2006-2008 | 2001-2008 | 2001- UDFA -CHN | premium | premium | premium |
| Billy Sadler | 2006-09-15 | boxscore | 24.000 | P | 6-0 | 195 | R | R | 1981-09-21 | Pensacola,FL | MLB | 2006-2009 | 2003-2009 | 2003- 6- 183-SFN | premium | premium | premium |
| Takashi Saito | 2006-04-09 | boxscore | 36.063 | P | 6-2 | 200 | L | R | 1970-02-14 | Miyagi,JP | MLB | 2006-2012 | 1992-2014 | 2006- UDFA -LAN | premium | premium | premium |
| Juan Salas | 2006-09-05 | boxscore | 27.309 | P | 6-2 | 230 | R | R | 1978-11-07 | Santo Domingo,DR | MLB | 2006-2008 | 1999-2009 | 1998- UDFA -TBA | premium | premium | premium |
| Jeff Salazar | 2006-09-07 | boxscore | 25.293 | RF-LF | 6-0 | 195 | L | L | 1980-11-24 | Oklahoma City,OK | MLB | 2006-2009 | 2002-2012 | 2002- 8- 231-COL | premium | premium | premium |
| Chris Sampson | 2006-06-02 | boxscore | 28.017 | P | 6-1 | 195 | R | R | 1978-05-23 | Channelview,TX | MLB | 2006-2010 | 1999-2011 | 1999- 8- 263-HOU | premium | premium | premium |
| Brian Sanches | 2006-06-01 | boxscore | 27.304 | P | 6-1 | 190 | R | R | 1978-08-08 | Beaumont,TX | MLB | 2006-2012 | 1997-2013 | 1999- 2- 54-KCA | premium | premium | premium |
| Angel Sanchez | 2006-09-23 | boxscore | 23.009 | 3B-SS | 6-1 | 205 | R | R | 1983-09-20 | Humacao,PR | MLB | 2006-2013 | 2001-2016 | 2001- 11- 325-KCA | premium | premium | premium |
| Anibal Sanchez | 2006-06-25 | boxscore | 22.124 | P | 6-0 | 207 | R | R | 1984-02-27 | Maracay,VZ | MLB | 2006-2022 | 2004-2022 | 2001- UDFA -BOS | premium | premium | premium |
| Jonathan Sanchez | 2006-05-28 | boxscore | 23.196 | P | 6-0 | 200 | L | L | 1982-11-19 | Mayaguez,PR | MLB | 2006-2013 | 2004-2019 | 2004- 27- 820-SFN | premium | premium | premium |
| Chad Santos | 2006-07-16 | boxscore | 25.085 | 1B | 5-11 | 220 | L | L | 1981-04-28 | Honolulu,HI | MLB | 2006-2006 | 1999-2007 | 1999- 22- 661-KCA | premium | premium | premium |
| Dennis Sarfate | 2006-09-03 | boxscore | 25.153 | P | 6-4 | 225 | R | R | 1981-04-09 | Queens,NY | MLB | 2006-2009 | 2000-2018 | 2001- 9- 268-MIL | premium | premium | premium |
| Chris Schroder | 2006-08-08 | boxscore | 27.360 | P | 6-3 | 210 | R | R | 1978-08-20 | Okarche,OK | MLB | 2006-2008 | 2001-2010 | 2001- 19- 562-MON | premium | premium | premium |
| Josh Sharpless | 2006-08-01 | boxscore | 25.193 | P | 6-5 | 240 | R | R | 1981-01-26 | Beaver,PA | MLB | 2006-2007 | 2003-2009 | 2003- 24- 705-PIT | premium | premium | premium |
| James Shields | 2006-05-31 | boxscore | 24.168 | P | 6-3 | 210 | R | R | 1981-12-20 | Newhall,CA | MLB | 2006-2018 | 2001-2018 | 2000- 16- 466-TBA | premium | premium | premium |
| Doug Slaten | 2006-09-04 | boxscore | 26.219 | P | 6-5 | 215 | L | L | 1980-02-04 | Venice,CA | MLB | 2006-2012 | 2000-2012 | 2000- 17- 519-ARI | premium | premium | premium |
| Brian Slocum | 2006-04-22 | boxscore | 25.032 | P | 6-2 | 215 | R | R | 1981-03-27 | New Rochelle,NY | MLB | 2006-2008 | 2000-2011 | 2002- 2- 63-CLE | premium | premium | premium |
| Matt Smith | 2006-04-14 | boxscore | 26.310 | P | 6-5 | 225 | L | L | 1979-06-15 | Las Vegas,NV | MLB | 2006-2007 | 1998-2008 | 2000- 4- 128-NYA | premium | premium | premium |
| Alay Soler | 2006-05-24 | boxscore | 26.234 | P | 6-1 | 240 | R | R | 1979-10-09 | Pinar del Rio,CU | MLB | 2006-2006 | 2006-2009 | 2004- UDFA -NYN | premium | premium | premium |
| Jeremy Sowers | 2006-06-25 | boxscore | 23.045 | P | 6-1 | 180 | L | L | 1983-05-17 | St. Clairsville,OH | MLB | 2006-2009 | 2002-2013 | 2004- 1- 6-CLE | premium | premium | premium |
| Chris Stewart | 2006-09-06 | boxscore | 24.205 | C | 6-4 | 215 | R | R | 1982-02-19 | Fontana,CA | MLB | 2006-2018 | 2001-2019 | 2001- 12- 373-CHA | premium | premium | premium |
| Phil Stockman | 2006-06-15 | boxscore | 26.148 | P | 6-8 | 250 | R | R | 1980-01-25 | Oldham,EN | MLB | 2006-2008 | 1998-2008 | 1997- UDFA -ARI | premium | premium | premium |
| Brian Stokes | 2006-09-03 | boxscore | 26.003 | P | 6-1 | 210 | R | R | 1979-09-07 | Montclair,CA | MLB | 2006-2010 | 1999-2011 | 1998- UDFA -TBA | premium | premium | premium |
| Eric Stults | 2006-09-05 | boxscore | 26.277 | P | 6-2 | 220 | L | L | 1979-12-09 | Plymouth,IN | MLB | 2006-2015 | 2002-2015 | 2002- 15- 451-LAN | premium | premium | premium |
| Ryan Sweeney | 2006-09-01 | boxscore | 21.198 | CF-OF | 6-4 | 225 | L | L | 1985-02-20 | Cedar Rapids,IA | MLB | 2006-2014 | 2003-2014 | 2003- 2- 52-CHA | premium | premium | premium |
| Taylor Tankersley | 2006-06-03 | boxscore | 23.094 | P | 6-0 | 210 | L | L | 1983-03-07 | Vicksburg,MS | MLB | 2006-2010 | 2002-2011 | 2004- 1- 27-MIA | premium | premium | premium |
| Jordan Tata | 2006-04-06 | boxscore | 24.204 | P | 6-6 | 220 | R | R | 1981-09-20 | Plano,TX | MLB | 2006-2007 | 2002-2009 | 2003- 16- 460-DET | premium | premium | premium |
| Ty Taubenheim | 2006-05-20 | boxscore | 23.190 | P | 6-5 | 228 | R | R | 1982-11-17 | Bellingham,WA | MLB | 2006-2008 | 2003-2010 | 2003- 19- 549-MIL | premium | premium | premium |
| Kevin Thompson | 2006-06-03 | boxscore | 26.265 | SS-3B | 5-10 | 195 | R | R | 1979-09-18 | Fort Worth,TX | MLB | 2006-2007 | 2000-2011 | 1999- 31- 951-NYA | premium | premium | premium |
| Mike Thompson | 2006-05-17 | boxscore | 25.198 | P | 6-4 | 210 | R | R | 1980-11-06 | Walsh,CO | MLB | 2006-2007 | 1999-2010 | 1999- 5- 172-SDN | premium | premium | premium |
| Scott Thorman | 2006-06-18 | boxscore | 24.169 | 1B-LF | 6-3 | 225 | L | R | 1982-01-06 | Cambridge,ON | MLB | 2006-2007 | 2000-2012 | 2000- 1- 30-ATL | premium | premium | premium |
| Sean Tracey | 2006-06-08 | boxscore | 25.212 | P | 6-1 | 205 | L | R | 1980-11-14 | Upland,CA | MLB | 2006-2006 | 2002-2015 | 2002- 8- 240-CHA | premium | premium | premium |
| Troy Tulowitzki | 2006-08-30 | boxscore | 21.329 | SS | 6-3 | 205 | R | R | 1984-10-10 | Santa Clara,CA | MLB | 2006-2019 | 2003-2019 | 2005- 1- 7-COL | premium | premium | premium |
| Dan Uggla | 2006-04-03 | boxscore | 26.029 | 2B | 5-11 | 210 | R | R | 1980-03-11 | Louisville,KY | MLB | 2006-2015 | 1999-2015 | 2001- 11- 338-ARI | premium | premium | premium |
| Jose Veras | 2006-08-05 | boxscore | 25.295 | P | 6-6 | 240 | R | R | 1980-10-20 | Santo Domingo,DR | MLB | 2006-2014 | 1998-2016 | 1998- UDFA -TBA | premium | premium | premium |
| Carlos Villanueva | 2006-05-23 | boxscore | 22.182 | P | 6-2 | 220 | R | R | 1983-11-28 | Santiago,DR | MLB | 2006-2016 | 2002-2016 | 2002- UDFA -SFN | premium | premium | premium |
| Jered Weaver | 2006-05-27 | boxscore | 23.241 | P | 6-7 | 210 | R | R | 1982-10-04 | Northridge,CA | MLB | 2006-2017 | 2002-2017 | 2004- 1- 12-ANA | premium | premium | premium |
| Reggie Willits | 2006-04-26 | boxscore | 24.337 | LF-RF | 5-11 | 185 | B | R | 1981-05-30 | Chickasha,OK | MLB | 2006-2011 | 2002-2011 | 2003- 7- 210-ANA | premium | premium | premium |
| Brian Wilson | 2006-04-23 | boxscore | 24.044 | P | 6-1 | 205 | R | R | 1982-03-16 | Winchester,MA | MLB | 2006-2014 | 2001-2014 | 2003- 24- 723-SFN | premium | premium | premium |
| Jason Windsor | 2006-07-17 | boxscore | 24.007 | P | 6-2 | 235 | R | R | 1982-07-16 | San Bernardino,CA | MLB | 2006-2006 | 2004-2008 | 2004- 3- 97-OAK | premium | premium | premium |
| Shane Youman | 2006-09-10 | boxscore | 26.341 | P | 6-4 | 220 | L | L | 1979-10-11 | New Iberia,LA | MLB | 2006-2007 | 1999-2016 | 2001- 43-1280-PIT | premium | premium | premium |
| Chris Young | 2006-08-18 | boxscore | 22.353 | CF | 6-2 | 200 | R | R | 1983-09-05 | Houston,TX | MLB | 2006-2018 | 2002-2018 | 2001- 16- 493-CHA | premium | premium | premium |
| Delmon Young | 2006-08-29 | boxscore | 20.354 | RF | 6-3 | 240 | R | R | 1985-09-14 | Montgomery,AL | MLB | 2006-2015 | 2004-2018 | 2003- 1- 1-TBA | premium | premium | premium |
| Delwyn Young | 2006-09-07 | boxscore | 24.075 | RF | 5-10 | 209 | B | R | 1982-06-30 | Los Angeles,CA | MLB | 2006-2010 | 2001-2016 | 2002- 4- 121-LAN | premium | premium | premium |
| Ben Zobrist | 2006-08-01 | boxscore | 25.073 | 2B | 6-3 | 210 | B | R | 1981-05-26 | Eureka,IL | MLB | 2006-2019 | 2004-2019 | 2004- 6- 184-HOU | premium | premium | premium |
| Joel Zumaya | 2006-04-03 | boxscore | 21.150 | P | 6-3 | 215 | R | R | 1984-11-09 | Chula Vista,CA | MLB | 2006-2010 | 2002-2010 | 2002- 11- 320-DET | premium | premium | premium |
| 220 record(s) |
