| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 10 | Marcus Semien | 30 | 2B | R | 118 | 162 | 652 | 115 | 173 | 39 | 2 | 45 | 102 | 15 | 1 | 66 | 146 | 3 | 0 | 3 | 0 | 9 | 351 | 724 | 86 | 87 | .265 | .334 | .538 | .872 | .396 | .273 | .276 | 9.12 | 20.17 | 2.21 | 14.49 | 2011- 6- 201-CHA | premium | premium | premium | MLB | 2013-2025 | 2009-2025 | 2021 |
| 11 | Bo Bichette | 23 | SS | R | 115 | 159 | 640 | 121 | 191 | 30 | 1 | 29 | 102 | 25 | 1 | 40 | 137 | 6 | 0 | 4 | 0 | 10 | 310 | 690 | 60 | 131 | .298 | .343 | .484 | .827 | .286 | .186 | .339 | 5.80 | 19.86 | 3.43 | 22.07 | 2016- 2- 66-TOR | premium | premium | premium | MLB | 2019-2025 | 2016-2025 | 2021 |
| 27 | Vladimir Guerrero | 22 | 1B | R | 134 | 161 | 604 | 123 | 188 | 29 | 1 | 48 | 111 | 4 | 1 | 86 | 110 | 6 | 0 | 2 | 7 | 20 | 363 | 698 | 78 | 110 | .311 | .401 | .601 | 1.002 | .437 | .290 | .313 | 12.32 | 15.76 | 1.28 | 12.58 | 2015- UDFA -TOR | premium | premium | premium | MLB | 2019-2025 | 2016-2025 | 2021 |
| 37 | Teoscar Hernandez | 28 | RF-LF | R | 118 | 143 | 550 | 92 | 163 | 29 | 0 | 32 | 116 | 12 | 4 | 36 | 148 | 7 | 0 | 2 | 1 | 5 | 288 | 595 | 61 | 102 | .296 | .346 | .524 | .870 | .307 | .228 | .352 | 6.05 | 24.87 | 4.11 | 17.19 | 2011- UDFA -HOU | premium | premium | premium | MLB | 2016-2025 | 2011-2025 | 2021 |
| 15 | Randal Grichuk | 29 | CF-RF | R | 95 | 149 | 511 | 59 | 123 | 25 | 1 | 22 | 81 | 0 | 3 | 27 | 114 | 3 | 0 | 4 | 0 | 17 | 216 | 545 | 48 | 75 | .241 | .281 | .423 | .704 | .229 | .182 | .266 | 4.95 | 20.92 | 4.22 | 23.23 | 2009- 1- 24-ANA | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 |
| 13 | Lourdes Gurriel | 27 | LF | R | 105 | 141 | 500 | 62 | 138 | 28 | 2 | 21 | 84 | 1 | 3 | 32 | 102 | 2 | 1 | 6 | 1 | 8 | 233 | 541 | 51 | 87 | .276 | .319 | .466 | .785 | .250 | .190 | .305 | 5.91 | 18.85 | 3.19 | 23.81 | 2016- UDFA -TOR | premium | premium | premium | MLB | 2018-2025 | 2017-2025 | 2021 |
| 4 | George Springer | 31 | CF-DH | R | 122 | 78 | 299 | 59 | 79 | 19 | 1 | 22 | 50 | 4 | 1 | 37 | 79 | 4 | 0 | 1 | 1 | 6 | 166 | 341 | 42 | 37 | .264 | .352 | .555 | .907 | .425 | .291 | .286 | 10.85 | 23.17 | 2.14 | 13.59 | 2011- 1- 11-HOU | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 |
| 8 | Cavan Biggio | 26 | 3B | L | 94 | 79 | 250 | 27 | 56 | 10 | 1 | 7 | 27 | 3 | 1 | 37 | 78 | 1 | 1 | 4 | 2 | 4 | 89 | 293 | 18 | 38 | .224 | .322 | .356 | .678 | .288 | .132 | .290 | 12.63 | 26.62 | 2.11 | 35.71 | 2016- 5- 162-TOR | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 5 | Santiago Espinal | 26 | 3B | R | 110 | 92 | 222 | 32 | 69 | 13 | 1 | 2 | 17 | 6 | 1 | 22 | 30 | 1 | 1 | 0 | 0 | 4 | 90 | 246 | 16 | 53 | .311 | .376 | .405 | .781 | .216 | .094 | .353 | 8.94 | 12.20 | 1.36 | 111.00 | 2016- 10- 298-BOS | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 |
| 7 | Reese McGuire | 26 | C | L | 91 | 78 | 198 | 22 | 50 | 15 | 0 | 1 | 10 | 0 | 0 | 15 | 44 | 2 | 1 | 1 | 0 | 4 | 68 | 217 | 16 | 34 | .253 | .310 | .343 | .653 | .167 | .090 | .318 | 6.91 | 20.28 | 2.93 | 198.00 | 2013- 1- 14-PIT | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 9 | Danny Jansen | 26 | C | R | 105 | 70 | 184 | 32 | 41 | 13 | 0 | 11 | 28 | 0 | 0 | 17 | 44 | 3 | 1 | 0 | 0 | 4 | 87 | 205 | 24 | 17 | .223 | .299 | .473 | .772 | .342 | .250 | .233 | 8.29 | 21.46 | 2.59 | 16.73 | 2013- 16- 475-TOR | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 30 | Alejandro Kirk | 22 | C | R | 105* | 60 | 165 | 19 | 40 | 8 | 0 | 8 | 24 | 0 | 0 | 19 | 22 | 3 | 0 | 2 | 0 | 7 | 72 | 189 | 16 | 24 | .242 | .328 | .436 | .764 | .309 | .194 | .234 | 10.05 | 11.64 | 1.16 | 20.63 | 2016- UDFA -TOR | premium | premium | premium | MLB | 2020-2025 | 2017-2025 | 2021 |
| 11 | Rowdy Tellez | 26 | DH-1B | L | 97 | 50 | 139 | 12 | 29 | 4 | 1 | 4 | 8 | 0 | 0 | 9 | 33 | 3 | 0 | 0 | 1 | 3 | 47 | 151 | 9 | 20 | .209 | .272 | .338 | .610 | .194 | .129 | .245 | 5.96 | 21.85 | 3.67 | 34.75 | 2013- 30- 895-TOR | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 14 | Corey Dickerson | 32 | LF | L | 100 | 46 | 131 | 16 | 37 | 6 | 2 | 4 | 15 | 4 | 1 | 9 | 23 | 0 | 0 | 0 | 1 | 3 | 59 | 140 | 12 | 25 | .282 | .329 | .450 | .779 | .260 | .168 | .317 | 6.43 | 16.43 | 2.56 | 32.75 | 2010- 8- 260-COL | premium | premium | premium | MLB | 2013-2023 | 2010-2023 | 2021 |
| 12 | Joe Panik | 30 | 3B | L | 78 | 42 | 114 | 9 | 28 | 6 | 0 | 2 | 11 | 0 | 0 | 8 | 14 | 0 | 0 | 1 | 0 | 4 | 40 | 123 | 8 | 20 | .246 | .293 | .351 | .644 | .175 | .105 | .263 | 6.50 | 11.38 | 1.75 | 57.00 | 2011- 1- 29-SFN | premium | premium | premium | MLB | 2014-2021 | 2009-2021 | 2021 |
| 74 | Breyvic Valera | 29 | 3B | B | 39 | 87 | 10 | 22 | 6 | 0 | 1 | 15 | 1 | 0 | 8 | 12 | 0 | 1 | 1 | 0 | 1 | 31 | 97 | 7 | 15 | .253 | .313 | .356 | .669 | .207 | .103 | .280 | 8.25 | 12.37 | 1.50 | 87.00 | 2010- UDFA -SLN | premium | premium | premium | MLB | 2017-2021 | 2011-2025 | 2021 | |
| 36 | Jonathan Davis | 29 | CF | R | 67* | 52 | 70 | 16 | 10 | 1 | 0 | 1 | 4 | 4 | 1 | 11 | 21 | 3 | 0 | 1 | 0 | 1 | 14 | 85 | 2 | 8 | .143 | .282 | .200 | .482 | .257 | .057 | .184 | 12.94 | 24.71 | 1.91 | 70.00 | 2013- 15- 445-TOR | premium | premium | premium | MLB | 2018-2023 | 2011-2024 | 2021 |
| 77 | Joshua Palacios | 25 | RF-LF | L | 13 | 35 | 7 | 7 | 0 | 0 | 0 | 4 | 0 | 0 | 3 | 11 | 2 | 1 | 1 | 0 | 0 | 7 | 42 | 0 | 7 | .200 | .293 | .200 | .493 | .086 | .000 | .280 | 7.14 | 26.19 | 3.67 | 0.00 | 2016- 4- 132-TOR | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 | |
| 66 | Kevin Smith | 24 | 3B | R | 18 | 32 | 2 | 3 | 0 | 0 | 1 | 1 | 0 | 0 | 3 | 11 | 1 | 0 | 0 | 0 | 0 | 6 | 36 | 1 | 2 | .094 | .194 | .188 | .382 | .188 | .094 | .100 | 8.33 | 30.56 | 3.67 | 32.00 | 2017- 4- 129-TOR | premium | premium | premium | MLB | 2021-2024 | 2015-2024 | 2021 | |
| 2 | Jake Lamb | 30 | 3B | L | 94* | 12 | 31 | 5 | 4 | 2 | 0 | 1 | 6 | 0 | 0 | 5 | 13 | 1 | 0 | 2 | 0 | 0 | 9 | 39 | 3 | 1 | .129 | .256 | .290 | .546 | .323 | .161 | .158 | 12.82 | 33.33 | 2.60 | 31.00 | 2012- 6- 213-ARI | premium | premium | premium | MLB | 2014-2023 | 2010-2025 | 2021 |
| 50 | Riley Adams | 25 | C | R | 105* | 12 | 28 | 2 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 12 | 0 | 0 | 0 | 0 | 1 | 5 | 30 | 2 | 1 | .107 | .167 | .179 | .346 | .143 | .072 | .188 | 6.67 | 40.00 | 6.00 | 0.00 | 2017- 3- 99-TOR | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 1 | Jarrod Dyson | 36 | CF | L | 77* | 25 | 13 | 4 | 1 | 0 | 0 | 0 | 0 | 2 | 2 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 17 | 0 | 1 | .077 | .294 | .077 | .371 | .308 | .000 | .125 | 23.53 | 29.41 | 1.25 | 0.00 | 2006- 50-1475-KCA | premium | premium | premium | MLB | 2010-2021 | 2006-2021 | 2021 |
| 48 | Ross Stripling | 31 | P | R | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2012- 5- 176-LAN | premium | premium | premium | MLB | 2016-2024 | 2009-2024 | 2021 | |
| 99 | Hyun Jin Ryu | 34 | P | R | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2012- UDFA -LAN | premium | premium | premium | MLB | 2013-2023 | 2013-2023 | 2021 | |
| 38 | Robbie Ray | 29 | P | L | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 20.00 | 0.00 | 0.00 | 2010- 12- 356-WAS | premium | premium | premium | MLB | 2014-2025 | 2011-2025 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 28 | Jared Hoying | 32 | LF | L | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2010- 10- 316-TEX | premium | premium | premium | MLB | 2016-2021 | 2008-2021 | 2021 | |
| 22 | Steven Matz | 30 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2009- 2- 72-NYN | premium | premium | premium | MLB | 2015-2025 | 2012-2025 | 2021 | |
| 6 | Alek Manoah | 23 | P | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2019- 1- 11-TOR | premium | premium | premium | MLB | 2021-2024 | 2017-2025 | 2021 | |
| 17 | Jose Berrios | 27 | P | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 2012- 1- 32-MIN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 | |
| 72 | Otto Lopez | 22 | 2B-LF | R | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2016- UDFA -TOR | premium | premium | premium | MLB | 2021-2025 | 2017-2025 | 2021 | |
| Totals: | 1694 | 5476 | 846 | 1455 | 285 | 13 | 262 | 816 | 81 | 20 | 496 | 1218 | 51 | 10 | 35 | 14 | 112 | 2552 | 6068 | 560 | 895 | .266 | .330 | .466 | .797 | .302 | .200 | .296 | 8.17 | 20.07 | 2.46 | 20.90 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 59 | Jeremy Beasley | 25 | R | 0 | 1 | 7.71 | 8 | 0 | 0 | 0 | 8 | 6 | 0 | 9.1 | 7 | 9 | 8 | 3 | 9 | 13 | 2 | 0 | 2 | 1.71 | 6.75 | 2.89 | 8.68 | 12.54 | 8.68 | 1.44 | 2017- 30- 895-ANA | premium | premium | premium | MLB | 2020-2022 | 2017-2025 | 2021 |
| 66 | Patrick Murphy | 26 | R | 0 | 1 | 4.82 | 8 | 0 | 0 | 0 | 8 | 1 | 0 | 9.1 | 12 | 6 | 5 | 1 | 4 | 6 | 1 | 0 | 2 | 1.71 | 11.57 | 0.96 | 3.86 | 5.79 | 5.79 | 1.50 | 2013- 3- 83-TOR | premium | premium | premium | MLB | 2020-2022 | 2014-2025 | 2021 |
| 31 | Thomas Hatch | 26 | R | 0 | 1 | 6.75 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 9.1 | 11 | 7 | 7 | 2 | 6 | 8 | 2 | 0 | 1 | 1.82 | 10.61 | 1.93 | 5.79 | 7.71 | 6.75 | 1.33 | 2016- 3- 104-CHN | premium | premium | premium | MLB | 2020-2025 | 2014-2025 | 2021 |
| 52 | Brad Hand | 31 | L | 0 | 2 | 7.27 | 11 | 0 | 0 | 0 | 11 | 5 | 0 | 8.2 | 13 | 10 | 7 | 3 | 3 | 5 | 1 | 0 | 0 | 1.85 | 13.50 | 3.12 | 3.12 | 5.19 | 10.38 | 1.67 | 2008- 2- 52-MIA | premium | premium | premium | MLB | 2011-2023 | 2008-2023 | 2021 |
| 28 | Joakim Soria | 37 | R | 0 | 0 | 7.88 | 10 | 0 | 0 | 0 | 10 | 0 | 0 | 8.0 | 8 | 7 | 7 | 2 | 4 | 9 | 1 | 0 | 0 | 1.50 | 9.00 | 2.25 | 4.50 | 10.13 | 7.88 | 2.25 | 2001- UDFA -LAN | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2021 |
| 36 | A.J. Cole | 29 | R | 0 | 0 | 1.13 | 6 | 0 | 0 | 0 | 6 | 4 | 1 | 8.0 | 6 | 1 | 1 | 1 | 1 | 7 | 0 | 0 | 0 | 0.88 | 6.75 | 1.13 | 1.13 | 7.88 | 1.13 | 7.00 | 2010- 4- 116-WAS | premium | premium | premium | MLB | 2015-2021 | 2010-2023 | 2021 |
| 17 | Jose Berrios | 27 | R | 5 | 4 | 3.58 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 70.1 | 64 | 30 | 28 | 8 | 13 | 78 | 0 | 0 | 7 | 1.09 | 8.19 | 1.02 | 1.66 | 9.98 | 3.84 | 6.00 | 2012- 1- 32-MIN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 |
| 60 | Kirby Snead | 26 | L | 0 | 1 | 2.35 | 7 | 0 | 0 | 0 | 7 | 2 | 0 | 7.2 | 7 | 3 | 2 | 0 | 2 | 7 | 1 | 0 | 1 | 1.17 | 8.22 | 0.00 | 2.35 | 8.22 | 3.52 | 3.50 | 2016- 10- 312-TOR | premium | premium | premium | MLB | 2021-2024 | 2014-2025 | 2021 |
| 65 | Ty Tice | 24 | R | 0 | 0 | 5.14 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 7.0 | 9 | 4 | 4 | 1 | 4 | 6 | 0 | 0 | 1 | 1.86 | 11.57 | 1.29 | 5.14 | 7.71 | 5.14 | 1.50 | 2017- 16- 489-TOR | premium | premium | premium | MLB | 2021-2021 | 2015-2024 | 2021 |
| 14 | Tanner Roark | 34 | R | 0 | 1 | 6.43 | 3 | 1 | 0 | 0 | 2 | 1 | 0 | 7.0 | 7 | 7 | 5 | 3 | 2 | 5 | 0 | 0 | 0 | 1.29 | 9.00 | 3.86 | 2.57 | 6.43 | 9.00 | 2.50 | 2008- 25- 753-TEX | premium | premium | premium | MLB | 2013-2021 | 2006-2021 | 2021 |
| 68 | Jordan Romano | 28 | R | 7 | 1 | 2.14 | 62 | 0 | 0 | 0 | 62 | 43 | 23 | 63.0 | 41 | 17 | 15 | 7 | 25 | 85 | 2 | 0 | 1 | 1.05 | 5.86 | 1.00 | 3.57 | 12.14 | 2.43 | 3.40 | 2014- 10- 294-TOR | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 44 | Connor Overton | 27 | R | 0 | 0 | 0.00 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 6.2 | 4 | 0 | 0 | 0 | 2 | 4 | 1 | 0 | 0 | 0.90 | 5.40 | 0.00 | 2.70 | 5.40 | 0.00 | 2.00 | 2014- 15- 437-MIA | premium | premium | premium | MLB | 2021-2023 | 2012-2025 | 2021 |
| 58 | Tim Mayza | 29 | L | 5 | 2 | 3.40 | 61 | 0 | 0 | 0 | 61 | 10 | 1 | 53.0 | 40 | 21 | 20 | 5 | 12 | 57 | 2 | 0 | 3 | 0.98 | 6.79 | 0.85 | 2.04 | 9.68 | 3.57 | 4.75 | 2013- 12- 355-TOR | premium | premium | premium | MLB | 2017-2025 | 2011-2025 | 2021 |
| 56 | Carl Edwards | 29 | R | 0 | 0 | 6.75 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 5.1 | 8 | 4 | 4 | 2 | 2 | 5 | 1 | 0 | 0 | 1.88 | 13.50 | 3.38 | 3.38 | 8.44 | 6.75 | 2.50 | 2011- 48-1464-TEX | premium | premium | premium | MLB | 2015-2025 | 2012-2025 | 2021 |
| 57 | Trent Thornton | 27 | R | 1 | 3 | 4.78 | 37 | 3 | 0 | 0 | 34 | 4 | 0 | 49.0 | 54 | 33 | 26 | 12 | 16 | 52 | 3 | 0 | 4 | 1.43 | 9.92 | 2.20 | 2.94 | 9.55 | 6.06 | 3.25 | 2015- 5- 139-HOU | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 90 | Adam Cimber | 30 | R | 2 | 2 | 1.69 | 39 | 0 | 0 | 0 | 39 | 9 | 1 | 37.1 | 31 | 10 | 7 | 2 | 5 | 30 | 0 | 0 | 2 | 0.96 | 7.47 | 0.48 | 1.21 | 7.23 | 2.41 | 6.00 | 2013- 9- 268-SDN | premium | premium | premium | MLB | 2018-2024 | 2010-2024 | 2021 |
| 47 | Anthony Kay | 26 | L | 1 | 2 | 5.61 | 11 | 5 | 0 | 0 | 6 | 0 | 0 | 33.2 | 38 | 22 | 21 | 7 | 18 | 39 | 2 | 0 | 3 | 1.66 | 10.16 | 1.87 | 4.81 | 10.43 | 5.88 | 2.17 | 2016- 1- 31-NYN | premium | premium | premium | MLB | 2019-2023 | 2014-2025 | 2021 |
| 34 | Trevor Richards | 28 | R | 4 | 2 | 3.31 | 32 | 0 | 0 | 0 | 32 | 5 | 0 | 32.2 | 16 | 13 | 12 | 7 | 10 | 37 | 1 | 0 | 0 | 0.80 | 4.41 | 1.93 | 2.76 | 10.19 | 3.58 | 3.70 | 2016- UDFA -MIA | premium | premium | premium | MLB | 2018-2025 | 2012-2025 | 2021 |
| 41 | Rafael Dolis | 33 | R | 2 | 3 | 5.63 | 39 | 0 | 0 | 0 | 39 | 18 | 3 | 32.0 | 29 | 21 | 20 | 2 | 27 | 39 | 4 | 1 | 3 | 1.75 | 8.16 | 0.56 | 7.59 | 10.97 | 5.91 | 1.44 | 2004- UDFA -CHN | premium | premium | premium | MLB | 2011-2021 | 2006-2025 | 2021 |
| 38 | Joel Payamps | 27 | R | 0 | 2 | 2.70 | 22 | 0 | 0 | 0 | 22 | 8 | 0 | 30.0 | 21 | 10 | 9 | 3 | 11 | 22 | 0 | 0 | 1 | 1.07 | 6.30 | 0.90 | 3.30 | 6.60 | 3.00 | 2.00 | 2011- UDFA -COL | premium | premium | premium | MLB | 2019-2025 | 2011-2025 | 2021 |
| 34 | Tyler Chatwood | 31 | R | 1 | 2 | 5.46 | 30 | 0 | 0 | 0 | 30 | 3 | 1 | 28.0 | 20 | 17 | 17 | 1 | 20 | 32 | 1 | 0 | 3 | 1.43 | 6.43 | 0.32 | 6.43 | 10.29 | 5.46 | 1.60 | 2008- 2- 74-ANA | premium | premium | premium | MLB | 2011-2021 | 2008-2024 | 2021 |
| 54 | Tayler Saucedo | 28 | L | 0 | 0 | 4.56 | 29 | 0 | 0 | 0 | 29 | 9 | 0 | 25.2 | 22 | 14 | 13 | 1 | 10 | 19 | 2 | 1 | 2 | 1.25 | 7.71 | 0.35 | 3.51 | 6.66 | 4.91 | 1.90 | 2015- 21- 632-TOR | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 63 | Anthony Castro | 26 | R | 1 | 2 | 4.74 | 25 | 0 | 0 | 0 | 25 | 7 | 1 | 24.2 | 23 | 15 | 13 | 4 | 8 | 32 | 4 | 0 | 3 | 1.26 | 8.39 | 1.46 | 2.92 | 11.68 | 5.47 | 4.00 | 2011- UDFA -DET | premium | premium | premium | MLB | 2020-2022 | 2014-2024 | 2021 |
| 56 | Ryan Borucki | 27 | L | 3 | 1 | 4.94 | 24 | 0 | 0 | 0 | 24 | 6 | 0 | 23.2 | 18 | 14 | 13 | 5 | 11 | 21 | 2 | 0 | 1 | 1.23 | 6.85 | 1.90 | 4.18 | 7.99 | 5.32 | 1.91 | 2012- 15- 475-TOR | premium | premium | premium | MLB | 2018-2025 | 2012-2025 | 2021 |
| 38 | Robbie Ray | 29 | L | 13 | 7 | 2.84 | 32 | 32 | 0 | 0 | 0 | 0 | 0 | 193.1 | 150 | 62 | 61 | 33 | 52 | 248 | 5 | 0 | 4 | 1.04 | 6.98 | 1.54 | 2.42 | 11.54 | 2.89 | 4.77 | 2010- 12- 356-WAS | premium | premium | premium | MLB | 2014-2025 | 2011-2025 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 99 | Hyun Jin Ryu | 34 | L | 14 | 10 | 4.37 | 31 | 31 | 1 | 1 | 0 | 0 | 0 | 169.0 | 170 | 85 | 82 | 24 | 37 | 143 | 2 | 0 | 2 | 1.22 | 9.05 | 1.28 | 1.97 | 7.62 | 4.53 | 3.86 | 2012- UDFA -LAN | premium | premium | premium | MLB | 2013-2023 | 2013-2023 | 2021 |
| 22 | Steven Matz | 30 | L | 14 | 7 | 3.82 | 29 | 29 | 0 | 0 | 0 | 0 | 0 | 150.2 | 158 | 70 | 64 | 18 | 43 | 144 | 5 | 1 | 6 | 1.33 | 9.44 | 1.08 | 2.57 | 8.60 | 4.18 | 3.35 | 2009- 2- 72-NYN | premium | premium | premium | MLB | 2015-2025 | 2012-2025 | 2021 |
| 29 | T.J. Zeuch | 25 | R | 0 | 2 | 6.60 | 5 | 3 | 0 | 0 | 2 | 0 | 0 | 15.0 | 21 | 16 | 11 | 6 | 9 | 8 | 0 | 0 | 0 | 2.00 | 12.60 | 3.60 | 5.40 | 4.80 | 9.60 | 0.89 | 2016- 1- 21-TOR | premium | premium | premium | MLB | 2019-2022 | 2014-2025 | 2021 |
| 24 | Nate Pearson | 24 | R | 1 | 1 | 4.20 | 12 | 1 | 0 | 0 | 11 | 4 | 0 | 15.0 | 14 | 8 | 7 | 2 | 12 | 20 | 5 | 0 | 0 | 1.73 | 8.40 | 1.20 | 7.20 | 12.00 | 4.80 | 1.67 | 2017- 1- 28-TOR | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 |
| 69 | Tommy Milone | 34 | L | 1 | 0 | 6.43 | 6 | 1 | 0 | 0 | 5 | 1 | 1 | 14.0 | 20 | 10 | 10 | 3 | 3 | 17 | 0 | 0 | 0 | 1.64 | 12.86 | 1.93 | 1.93 | 10.93 | 6.43 | 5.67 | 2008- 10- 301-WAS | premium | premium | premium | MLB | 2011-2023 | 2006-2024 | 2021 |
| 67 | Julian Merryweather | 29 | R | 0 | 1 | 4.85 | 13 | 1 | 0 | 0 | 12 | 4 | 2 | 13.0 | 13 | 7 | 7 | 4 | 4 | 12 | 2 | 0 | 1 | 1.31 | 9.00 | 2.77 | 2.77 | 8.31 | 4.85 | 3.00 | 2014- 5- 158-CLE | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 |
| 6 | Alek Manoah | 23 | R | 9 | 2 | 3.22 | 20 | 20 | 0 | 0 | 0 | 0 | 0 | 111.2 | 77 | 44 | 40 | 12 | 40 | 127 | 0 | 1 | 16 | 1.05 | 6.21 | 0.97 | 3.22 | 10.24 | 3.55 | 3.18 | 2019- 1- 11-TOR | premium | premium | premium | MLB | 2021-2024 | 2017-2025 | 2021 |
| 48 | Ross Stripling | 31 | R | 5 | 7 | 4.80 | 24 | 19 | 0 | 0 | 5 | 1 | 0 | 101.1 | 99 | 55 | 54 | 23 | 30 | 94 | 0 | 0 | 2 | 1.27 | 8.79 | 2.04 | 2.66 | 8.35 | 4.88 | 3.13 | 2012- 5- 176-LAN | premium | premium | premium | MLB | 2016-2024 | 2009-2024 | 2021 |
| 64 | Travis Bergen | 27 | L | 2 | 0 | 1.69 | 10 | 1 | 0 | 0 | 9 | 2 | 0 | 10.2 | 5 | 2 | 2 | 1 | 8 | 6 | 0 | 0 | 2 | 1.22 | 4.22 | 0.84 | 6.75 | 5.06 | 1.69 | 0.75 | 2015- 7- 212-TOR | premium | premium | premium | MLB | 2019-2021 | 2013-2022 | 2021 |
| 35 | David Phelps | 34 | R | 0 | 0 | 0.87 | 11 | 1 | 0 | 0 | 10 | 1 | 0 | 10.1 | 8 | 2 | 1 | 0 | 4 | 15 | 0 | 0 | 1 | 1.16 | 6.97 | 0.00 | 3.48 | 13.06 | 1.74 | 3.75 | 2008- 14- 440-NYA | premium | premium | premium | MLB | 2012-2022 | 2006-2022 | 2021 |
| 23 | Jacob Barnes | 31 | R | 0 | 1 | 6.30 | 10 | 0 | 0 | 0 | 10 | 1 | 0 | 10.0 | 12 | 7 | 7 | 1 | 6 | 15 | 0 | 0 | 1 | 1.80 | 10.80 | 0.90 | 5.40 | 13.50 | 6.30 | 2.50 | 2011- 14- 431-MIL | premium | premium | premium | MLB | 2016-2025 | 2009-2025 | 2021 |
| 43 | Bryan Baker | 26 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 1.00 | 9.00 | 0.00 | 0.00 | 9.00 | 0.00 | 0.00 | 2016- 11- 320-COL | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 51 | Nick Allgeyer | 25 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 2018- 12- 356-TOR | premium | premium | premium | MLB | 2021-2021 | 2015-2023 | 2021 |
| Totals: | 91 | 71 | 3.91 | 698 | 162 | 1 | 1 | 161 | 536 | 34 | 1405.1 | 1257 | 663 | 610 | 209 | 473 | 1468 | 54 | 4 | 75 | 1.23 | 8.05 | 1.34 | 3.03 | 9.40 | 4.25 | 3.10 | premium | premium | premium |