| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 8 | Brandon Lowe | 26 | 2B | L | 116 | 149 | 535 | 97 | 132 | 31 | 0 | 39 | 99 | 7 | 1 | 68 | 167 | 9 | 0 | 3 | 4 | 2 | 280 | 615 | 70 | 62 | .247 | .340 | .523 | .863 | .415 | .276 | .280 | 11.06 | 27.15 | 2.46 | 13.72 | 2015- 3- 87-TBA | premium | premium | premium | MLB | 2018-2025 | 2014-2025 | 2021 |
| 56 | Randy Arozarena | 26 | LF-RF | R | 111 | 141 | 529 | 94 | 145 | 32 | 3 | 20 | 69 | 20 | 10 | 56 | 170 | 14 | 0 | 5 | 4 | 9 | 243 | 604 | 55 | 90 | .274 | .356 | .459 | .815 | .310 | .185 | .363 | 9.27 | 28.15 | 3.04 | 26.45 | 2016- UDFA -SLN | premium | premium | premium | MLB | 2019-2025 | 2016-2025 | 2021 |
| 17 | Austin Meadows | 26 | LF-DH | L | 104 | 142 | 518 | 79 | 121 | 29 | 3 | 27 | 106 | 4 | 3 | 59 | 122 | 6 | 0 | 8 | 3 | 4 | 237 | 591 | 59 | 62 | .234 | .315 | .458 | .773 | .340 | .224 | .249 | 9.98 | 20.64 | 2.07 | 19.19 | 2013- 1- 9-PIT | premium | premium | premium | MLB | 2018-2023 | 2013-2023 | 2021 |
| 2 | Yandy Diaz | 29 | 1B-3B | R | 103 | 134 | 465 | 62 | 119 | 20 | 1 | 13 | 64 | 1 | 1 | 69 | 85 | 3 | 0 | 4 | 4 | 11 | 180 | 541 | 34 | 85 | .256 | .353 | .387 | .740 | .280 | .131 | .286 | 12.75 | 15.71 | 1.23 | 35.77 | 2013- UDFA -CLE | premium | premium | premium | MLB | 2017-2025 | 2014-2025 | 2021 |
| 18 | Joey Wendle | 31 | 3B | L | 100 | 136 | 460 | 73 | 122 | 31 | 4 | 11 | 54 | 8 | 6 | 28 | 113 | 10 | 0 | 3 | 4 | 9 | 194 | 501 | 46 | 76 | .265 | .319 | .422 | .741 | .222 | .157 | .327 | 5.59 | 22.55 | 4.04 | 41.82 | 2012- 6- 203-CLE | premium | premium | premium | MLB | 2016-2024 | 2012-2024 | 2021 |
| 13 | Manuel Margot | 26 | RF | R | 95 | 125 | 421 | 55 | 107 | 18 | 3 | 10 | 57 | 13 | 8 | 37 | 70 | 1 | 1 | 4 | 2 | 4 | 161 | 464 | 31 | 76 | .254 | .313 | .382 | .695 | .228 | .128 | .281 | 7.97 | 15.09 | 1.89 | 42.10 | 2011- UDFA -BOS | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 |
| 39 | Kevin Kiermaier | 31 | CF | L | 98 | 122 | 348 | 54 | 90 | 19 | 7 | 4 | 37 | 9 | 5 | 33 | 99 | 5 | 0 | 4 | 2 | 4 | 135 | 390 | 30 | 60 | .259 | .328 | .388 | .716 | .236 | .129 | .345 | 8.46 | 25.38 | 3.00 | 87.00 | 2010- 31- 941-TBA | premium | premium | premium | MLB | 2013-2024 | 2010-2024 | 2021 |
| 10 | Mike Zunino | 30 | C | R | 115 | 109 | 333 | 64 | 72 | 11 | 2 | 33 | 62 | 0 | 0 | 34 | 132 | 7 | 0 | 1 | 0 | 7 | 186 | 375 | 46 | 26 | .216 | .301 | .559 | .860 | .444 | .343 | .231 | 9.07 | 35.20 | 3.88 | 10.09 | 2012- 1- 3-SEA | premium | premium | premium | MLB | 2013-2023 | 2010-2023 | 2021 |
| 5 | Wander Franco | 20 | SS | B | 110 | 70 | 281 | 53 | 81 | 18 | 5 | 7 | 39 | 2 | 1 | 24 | 37 | 2 | 0 | 1 | 0 | 2 | 130 | 308 | 30 | 51 | .288 | .347 | .463 | .810 | .263 | .175 | .311 | 7.79 | 12.01 | 1.54 | 40.14 | 2017- UDFA -TBA | premium | premium | premium | MLB | 2021-2023 | 2018-2023 | 2021 |
| 26 | Ji Man Choi | 30 | 1B | L | 106 | 83 | 258 | 36 | 59 | 14 | 0 | 11 | 45 | 0 | 0 | 45 | 87 | 2 | 0 | 0 | 0 | 5 | 106 | 305 | 25 | 34 | .229 | .348 | .411 | .759 | .357 | .182 | .300 | 14.75 | 28.52 | 1.93 | 23.45 | 2010- UDFA -SEA | premium | premium | premium | MLB | 2016-2023 | 2010-2024 | 2021 |
| 35 | Brett Phillips | 27 | CF-RF | L | 99 | 118 | 253 | 50 | 51 | 9 | 3 | 13 | 44 | 14 | 3 | 33 | 113 | 2 | 2 | 2 | 0 | 3 | 105 | 292 | 25 | 26 | .202 | .297 | .415 | .712 | .387 | .213 | .295 | 11.30 | 38.70 | 3.42 | 19.46 | 2012- 6- 189-HOU | premium | premium | premium | MLB | 2017-2023 | 2012-2025 | 2021 |
| 28 | Francisco Mejia | 25 | C | B | 101 | 84 | 250 | 31 | 65 | 15 | 3 | 6 | 35 | 0 | 0 | 17 | 49 | 7 | 1 | 2 | 0 | 4 | 104 | 277 | 24 | 41 | .260 | .322 | .416 | .738 | .224 | .156 | .299 | 6.14 | 17.69 | 2.88 | 41.67 | 2012- UDFA -CLE | premium | premium | premium | MLB | 2017-2023 | 2013-2025 | 2021 |
| 23 | Nelson Cruz | 40 | DH | R | 111 | 55 | 217 | 35 | 49 | 8 | 0 | 13 | 36 | 0 | 0 | 16 | 63 | 2 | 0 | 2 | 4 | 4 | 96 | 237 | 21 | 28 | .226 | .283 | .442 | .725 | .290 | .216 | .252 | 6.75 | 26.58 | 3.94 | 16.69 | 1998- UDFA -NYN | premium | premium | premium | MLB | 2005-2023 | 2001-2023 | 2021 |
| 6 | Taylor Walls | 24 | SS | B | 88* | 54 | 152 | 15 | 32 | 10 | 0 | 1 | 15 | 4 | 2 | 23 | 49 | 0 | 1 | 0 | 0 | 3 | 45 | 176 | 11 | 21 | .211 | .314 | .296 | .610 | .250 | .085 | .304 | 13.07 | 27.84 | 2.13 | 152.00 | 2017- 3- 79-TBA | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 43 | Mike Brosseau | 27 | 2B-3B | R | 86* | 57 | 150 | 21 | 28 | 9 | 0 | 5 | 18 | 2 | 0 | 15 | 53 | 2 | 0 | 2 | 0 | 1 | 52 | 169 | 14 | 14 | .187 | .266 | .347 | .613 | .273 | .160 | .245 | 8.88 | 31.36 | 3.53 | 30.00 | 2016- UDFA -TBA | premium | premium | premium | MLB | 2019-2023 | 2013-2025 | 2021 |
| 1 | Willy Adames | 25 | SS | R | 111 | 41 | 132 | 16 | 26 | 6 | 1 | 5 | 15 | 1 | 2 | 10 | 51 | 0 | 0 | 0 | 0 | 1 | 49 | 142 | 12 | 14 | .197 | .254 | .371 | .625 | .242 | .174 | .276 | 7.04 | 35.92 | 5.10 | 26.40 | 2012- UDFA -DET | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 28 | Yoshi Tsutsugo | 29 | 1B-DH | L | 95 | 26 | 78 | 5 | 13 | 4 | 0 | 0 | 5 | 0 | 0 | 8 | 27 | 0 | 1 | 0 | 0 | 1 | 17 | 87 | 4 | 9 | .167 | .244 | .218 | .462 | .154 | .051 | .255 | 9.20 | 31.03 | 3.38 | 0.00 | 2019- UDFA -TBA | premium | premium | premium | MLB | 2020-2022 | 2010-2025 | 2021 |
| 8 | Jordan Luplow | 27 | 1B | R | 106* | 25 | 65 | 11 | 16 | 3 | 0 | 4 | 8 | 1 | 0 | 7 | 26 | 0 | 0 | 0 | 0 | 1 | 31 | 72 | 7 | 9 | .246 | .319 | .477 | .796 | .354 | .231 | .343 | 9.72 | 36.11 | 3.71 | 16.25 | 2014- 3- 100-PIT | premium | premium | premium | MLB | 2017-2023 | 2012-2025 | 2021 |
| 7 | Vidal Brujan | 23 | 2B-RF | B | 10 | 26 | 3 | 2 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | 26 | 0 | 2 | .077 | .077 | .077 | .154 | .038 | .000 | .111 | 0.00 | 30.77 | 0.00 | 0.00 | 2014- UDFA -TBA | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 | |
| 30 | Kevin Padlo | 24 | 3B-1B | R | 9 | 12 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | 14 | 1 | 0 | .083 | .214 | .167 | .381 | .250 | .084 | .250 | 14.29 | 57.14 | 4.00 | 0.00 | 2014- 5- 143-COL | premium | premium | premium | MLB | 2021-2023 | 2014-2024 | 2021 | |
| 52 | Kevan Smith | 33 | C | R | 62* | 3 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2011- 7- 231-CHA | premium | premium | premium | MLB | 2016-2021 | 2008-2021 | 2021 |
| 48 | Ryan Yarbrough | 29 | P | R | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2014- 4- 111-SEA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 | |
| 21 | Rich Hill | 41 | P | L | 3 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .250 | .250 | .250 | .500 | .000 | .000 | .500 | 0.00 | 50.00 | 0.00 | 0.00 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2021 | |
| 57 | Drew Rasmussen | 25 | P | R | 3 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | .333 | 0.00 | 0.00 | 0.00 | 0.00 | 2018- 6- 185-MIL | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 | |
| 52 | Michael Wacha | 29 | P | R | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2012- 1- 19-SLN | premium | premium | premium | MLB | 2013-2025 | 2010-2025 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 20 | Tyler Glasnow | 27 | P | L | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2011- 5- 152-PIT | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 | |
| 64 | Joseph Odom | 29 | C | R | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 50.00 | 0.00 | 0.00 | 2013- 13- 403-ATL | premium | premium | premium | MLB | 2020-2021 | 2013-2022 | 2021 | |
| 19 | Josh Fleming | 25 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2017- 5- 139-TBA | premium | premium | premium | MLB | 2020-2024 | 2017-2025 | 2021 | |
| 53 | Josh Lowe | 23 | RF-LF | L | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | 1.000 | 1.000 | 1.000 | 2.000 | 2.000 | .000 | 1.000 | 50.00 | 0.00 | 0.00 | 0.00 | 2016- 1- 13-TBA | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 | |
| Totals: | 1710 | 5507 | 857 | 1335 | 288 | 35 | 222 | 810 | 88 | 42 | 585 | 1542 | 72 | 6 | 41 | 27 | 75 | 2359 | 6211 | 545 | 790 | .242 | .321 | .428 | .749 | .301 | .186 | .294 | 9.42 | 24.83 | 2.64 | 24.81 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 21 | Rich Hill | 41 | L | 6 | 4 | 3.87 | 19 | 19 | 0 | 0 | 0 | 0 | 0 | 95.1 | 75 | 41 | 41 | 14 | 36 | 91 | 3 | 1 | 8 | 1.16 | 7.08 | 1.32 | 3.40 | 8.59 | 3.87 | 2.53 | 2002- 4- 112-CHN | premium | premium | premium | MLB | 2005-2025 | 2000-2025 | 2021 |
| 21 | Cody Reed | 28 | L | 0 | 1 | 3.72 | 12 | 0 | 0 | 0 | 12 | 5 | 0 | 9.2 | 8 | 5 | 4 | 1 | 6 | 7 | 0 | 0 | 1 | 1.45 | 7.45 | 0.93 | 5.59 | 6.52 | 4.66 | 1.17 | 2013- 2- 46-KCA | premium | premium | premium | MLB | 2016-2021 | 2012-2025 | 2021 |
| 20 | Tyler Glasnow | 27 | R | 5 | 2 | 2.66 | 14 | 14 | 0 | 0 | 0 | 0 | 0 | 88.0 | 55 | 26 | 26 | 10 | 27 | 123 | 8 | 0 | 0 | 0.93 | 5.63 | 1.02 | 2.76 | 12.58 | 2.66 | 4.56 | 2011- 5- 152-PIT | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 |
| 61 | Luis Patino | 21 | R | 5 | 3 | 4.31 | 19 | 15 | 0 | 0 | 4 | 0 | 0 | 77.1 | 69 | 40 | 37 | 12 | 29 | 74 | 7 | 1 | 3 | 1.27 | 8.03 | 1.40 | 3.38 | 8.61 | 4.66 | 2.55 | 2016- UDFA -SDN | premium | premium | premium | MLB | 2020-2023 | 2017-2025 | 2021 |
| 36 | Andrew Kittredge | 31 | R | 9 | 3 | 1.88 | 57 | 4 | 0 | 0 | 53 | 15 | 8 | 71.2 | 55 | 21 | 15 | 7 | 15 | 77 | 5 | 0 | 3 | 0.98 | 6.91 | 0.88 | 1.88 | 9.67 | 2.64 | 5.13 | 2011- UDFA -SEA | premium | premium | premium | MLB | 2017-2025 | 2009-2025 | 2021 |
| 31 | Collin McHugh | 34 | R | 6 | 1 | 1.55 | 37 | 7 | 0 | 0 | 30 | 11 | 1 | 64.0 | 48 | 15 | 11 | 3 | 12 | 74 | 2 | 1 | 2 | 0.94 | 6.75 | 0.42 | 1.69 | 10.41 | 2.11 | 6.17 | 2008- 18- 554-NYN | premium | premium | premium | MLB | 2012-2023 | 2008-2023 | 2021 |
| 70 | Nick Anderson | 30 | R | 0 | 1 | 4.50 | 6 | 0 | 0 | 0 | 6 | 2 | 1 | 6.0 | 4 | 3 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 1.00 | 6.00 | 3.00 | 3.00 | 1.50 | 4.50 | 0.50 | 2015- UDFA -MIN | premium | premium | premium | MLB | 2019-2025 | 2012-2025 | 2021 |
| 57 | Drew Rasmussen | 25 | R | 4 | 0 | 2.44 | 20 | 10 | 0 | 0 | 10 | 2 | 0 | 59.0 | 44 | 16 | 16 | 3 | 13 | 48 | 2 | 0 | 0 | 0.97 | 6.71 | 0.46 | 1.98 | 7.32 | 2.44 | 3.69 | 2018- 6- 185-MIL | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 |
| 59 | Jeffrey Springs | 28 | L | 5 | 1 | 3.43 | 43 | 0 | 0 | 0 | 43 | 9 | 2 | 44.2 | 35 | 21 | 17 | 9 | 14 | 63 | 3 | 0 | 0 | 1.10 | 7.05 | 1.81 | 2.82 | 12.69 | 4.23 | 4.50 | 2015- 30- 888-TEX | premium | premium | premium | MLB | 2018-2025 | 2012-2025 | 2021 |
| 29 | Pete Fairbanks | 27 | R | 3 | 6 | 3.59 | 47 | 0 | 0 | 0 | 47 | 17 | 5 | 42.2 | 40 | 22 | 17 | 2 | 21 | 56 | 3 | 0 | 1 | 1.43 | 8.44 | 0.42 | 4.43 | 11.81 | 4.64 | 2.67 | 2015- 9- 258-TEX | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 45 | Brent Honeywell | 26 | R | 0 | 0 | 8.31 | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 4.1 | 5 | 4 | 4 | 2 | 3 | 4 | 0 | 0 | 0 | 1.85 | 10.38 | 4.15 | 6.23 | 8.31 | 8.31 | 1.33 | 2014- 2- 72-TBA | premium | premium | premium | MLB | 2021-2024 | 2014-2024 | 2021 |
| 56 | Chris Ellis | 28 | R | 1 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 4.0 | 3 | 0 | 0 | 0 | 1 | 7 | 1 | 0 | 0 | 1.00 | 6.75 | 0.00 | 2.25 | 15.75 | 0.00 | 7.00 | 2014- 3- 88-ANA | premium | premium | premium | MLB | 2019-2022 | 2012-2025 | 2021 |
| 54 | J.P. Feyereisen | 28 | R | 4 | 2 | 2.45 | 34 | 0 | 0 | 0 | 34 | 10 | 3 | 36.2 | 26 | 14 | 10 | 3 | 22 | 33 | 2 | 0 | 0 | 1.31 | 6.38 | 0.74 | 5.40 | 8.10 | 3.44 | 1.50 | 2014- 16- 488-CLE | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 |
| 63 | Diego Castillo | 27 | R | 2 | 4 | 2.72 | 37 | 0 | 0 | 0 | 37 | 26 | 14 | 36.1 | 26 | 14 | 11 | 5 | 10 | 49 | 1 | 0 | 1 | 0.99 | 6.44 | 1.24 | 2.48 | 12.14 | 3.47 | 4.90 | 2014- UDFA -TBA | premium | premium | premium | MLB | 2018-2024 | 2014-2025 | 2021 |
| 58 | Louis Head | 31 | R | 2 | 0 | 2.31 | 27 | 2 | 0 | 0 | 25 | 12 | 0 | 35.0 | 21 | 10 | 9 | 2 | 9 | 32 | 1 | 0 | 3 | 0.86 | 5.40 | 0.51 | 2.31 | 8.23 | 2.57 | 3.56 | 2012- 18- 563-CLE | premium | premium | premium | MLB | 2021-2022 | 2009-2023 | 2021 |
| 81 | Ryan Thompson | 29 | R | 3 | 2 | 2.38 | 36 | 0 | 0 | 0 | 36 | 2 | 0 | 34.0 | 26 | 11 | 9 | 3 | 9 | 37 | 1 | 0 | 2 | 1.03 | 6.88 | 0.79 | 2.38 | 9.79 | 2.91 | 4.11 | 2014- 23- 676-HOU | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 |
| 60 | Evan Phillips | 26 | R | 0 | 0 | 3.00 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 3.0 | 3 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 1.00 | 9.00 | 3.00 | 0.00 | 6.00 | 3.00 | 0.00 | 2015- 17- 510-ATL | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 37 | Matt Wisler | 28 | R | 2 | 3 | 2.15 | 27 | 0 | 0 | 0 | 27 | 4 | 1 | 29.1 | 22 | 11 | 7 | 2 | 5 | 36 | 1 | 1 | 1 | 0.92 | 6.75 | 0.61 | 1.53 | 11.05 | 3.38 | 7.20 | 2011- 7- 233-SDN | premium | premium | premium | MLB | 2015-2022 | 2011-2023 | 2021 |
| 15 | Chris Mazza | 31 | R | 0 | 0 | 4.61 | 14 | 0 | 0 | 0 | 14 | 7 | 1 | 27.1 | 26 | 14 | 14 | 3 | 7 | 21 | 3 | 0 | 2 | 1.21 | 8.56 | 0.99 | 2.30 | 6.91 | 4.61 | 3.00 | 2011- 27- 838-MIN | premium | premium | premium | MLB | 2019-2022 | 2012-2025 | 2021 |
| 84 | JT Chargois | 30 | R | 5 | 1 | 1.90 | 25 | 0 | 0 | 0 | 25 | 3 | 0 | 23.2 | 15 | 5 | 5 | 3 | 14 | 24 | 0 | 0 | 1 | 1.23 | 5.70 | 1.14 | 5.32 | 9.13 | 1.90 | 1.71 | 2012- 2- 72-MIN | premium | premium | premium | MLB | 2016-2024 | 2010-2025 | 2021 |
| 75 | Dietrich Enns | 30 | L | 2 | 0 | 2.82 | 9 | 0 | 0 | 0 | 9 | 3 | 2 | 22.1 | 17 | 8 | 7 | 1 | 6 | 25 | 0 | 0 | 0 | 1.03 | 6.85 | 0.40 | 2.42 | 10.07 | 3.22 | 4.17 | 2012- 19- 607-NYA | premium | premium | premium | MLB | 2017-2025 | 2010-2025 | 2021 |
| 23 | DJ Johnson | 31 | R | 0 | 0 | 0.00 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 2.2 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 6.75 | 0.00 | 0.00 | 2010- UDFA -TBA | premium | premium | premium | MLB | 2018-2021 | 2010-2025 | 2021 |
| 28 | Francisco Mejia | 25 | R | 0 | 0 | 27.00 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 2.0 | 6 | 6 | 6 | 1 | 0 | 0 | 0 | 0 | 2 | 3.00 | 27.00 | 4.50 | 0.00 | 0.00 | 27.00 | 0.00 | 2012- UDFA -CLE | premium | premium | premium | MLB | 2017-2023 | 2013-2025 | 2021 |
| 60 | David Hess | 27 | R | 0 | 0 | 27.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 2.0 | 8 | 6 | 6 | 3 | 1 | 2 | 0 | 0 | 0 | 4.50 | 36.00 | 13.50 | 4.50 | 9.00 | 27.00 | 2.00 | 2014- 5- 151-BAL | premium | premium | premium | MLB | 2018-2021 | 2012-2025 | 2021 |
| 55 | Adam Conley | 31 | L | 0 | 0 | 2.29 | 17 | 0 | 0 | 0 | 17 | 3 | 0 | 19.2 | 14 | 5 | 5 | 2 | 6 | 16 | 0 | 0 | 2 | 1.02 | 6.41 | 0.92 | 2.75 | 7.32 | 2.29 | 2.67 | 2011- 2- 72-MIA | premium | premium | premium | MLB | 2015-2021 | 2009-2021 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 22 | Chris Archer | 32 | R | 1 | 1 | 4.66 | 6 | 5 | 0 | 0 | 1 | 0 | 0 | 19.1 | 18 | 11 | 10 | 3 | 8 | 21 | 1 | 0 | 0 | 1.34 | 8.38 | 1.40 | 3.72 | 9.78 | 5.12 | 2.63 | 2006- 5- 161-CLE | premium | premium | premium | MLB | 2012-2022 | 2006-2022 | 2021 |
| 60 | Hunter Strickland | 32 | R | 0 | 0 | 1.69 | 13 | 0 | 0 | 0 | 13 | 7 | 0 | 16.0 | 14 | 4 | 3 | 1 | 6 | 16 | 1 | 0 | 0 | 1.25 | 7.88 | 0.56 | 3.38 | 9.00 | 2.25 | 2.67 | 2007- 18- 564-BOS | premium | premium | premium | MLB | 2014-2025 | 2007-2025 | 2021 |
| 46 | Shawn Armstrong | 30 | R | 1 | 0 | 4.50 | 11 | 0 | 0 | 0 | 11 | 3 | 0 | 16.0 | 11 | 8 | 8 | 5 | 5 | 22 | 0 | 0 | 1 | 1.00 | 6.19 | 2.81 | 2.81 | 12.38 | 4.50 | 4.40 | 2011- 18- 548-CLE | premium | premium | premium | MLB | 2015-2025 | 2009-2025 | 2021 |
| 48 | Ryan Yarbrough | 29 | L | 9 | 7 | 5.11 | 30 | 21 | 1 | 0 | 9 | 0 | 0 | 155.0 | 163 | 96 | 88 | 25 | 27 | 117 | 1 | 1 | 9 | 1.23 | 9.46 | 1.45 | 1.57 | 6.79 | 5.57 | 4.33 | 2014- 4- 111-SEA | premium | premium | premium | MLB | 2018-2025 | 2013-2025 | 2021 |
| 71 | Ryan Sherriff | 31 | L | 0 | 1 | 5.52 | 16 | 0 | 0 | 0 | 16 | 6 | 1 | 14.2 | 14 | 11 | 9 | 0 | 9 | 16 | 2 | 0 | 4 | 1.57 | 8.59 | 0.00 | 5.52 | 9.82 | 6.75 | 1.78 | 2011- 28- 860-SLN | premium | premium | premium | MLB | 2017-2023 | 2011-2025 | 2021 |
| 11 | Shane Baz | 22 | R | 2 | 0 | 2.03 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 13.1 | 6 | 3 | 3 | 3 | 3 | 18 | 1 | 0 | 0 | 0.68 | 4.05 | 2.03 | 2.03 | 12.15 | 2.03 | 6.00 | 2017- 1- 12-PIT | premium | premium | premium | MLB | 2021-2025 | 2017-2025 | 2021 |
| 52 | Michael Wacha | 29 | R | 3 | 5 | 5.05 | 29 | 23 | 0 | 0 | 6 | 1 | 0 | 124.2 | 132 | 73 | 70 | 23 | 31 | 121 | 5 | 0 | 4 | 1.31 | 9.53 | 1.66 | 2.24 | 8.74 | 5.27 | 3.90 | 2012- 1- 19-SLN | premium | premium | premium | MLB | 2013-2025 | 2010-2025 | 2021 |
| 62 | Shane McClanahan | 24 | L | 10 | 6 | 3.43 | 25 | 25 | 0 | 0 | 0 | 0 | 0 | 123.1 | 120 | 49 | 47 | 14 | 37 | 141 | 9 | 0 | 2 | 1.27 | 8.76 | 1.02 | 2.70 | 10.29 | 3.58 | 3.81 | 2018- 1- 31-TBA | premium | premium | premium | MLB | 2021-2023 | 2017-2025 | 2021 |
| 34 | Trevor Richards | 28 | R | 0 | 0 | 4.50 | 6 | 0 | 0 | 0 | 6 | 2 | 1 | 12.0 | 9 | 6 | 6 | 2 | 3 | 16 | 1 | 0 | 0 | 1.00 | 6.75 | 1.50 | 2.25 | 12.00 | 4.50 | 5.33 | 2016- UDFA -MIA | premium | premium | premium | MLB | 2018-2025 | 2012-2025 | 2021 |
| 30 | David Robertson | 36 | R | 0 | 0 | 4.50 | 12 | 1 | 0 | 0 | 11 | 1 | 0 | 12.0 | 11 | 7 | 6 | 2 | 4 | 16 | 0 | 0 | 0 | 1.25 | 8.25 | 1.50 | 3.00 | 12.00 | 5.25 | 4.00 | 2006- 17- 524-NYA | premium | premium | premium | MLB | 2008-2025 | 2005-2025 | 2021 |
| 19 | Josh Fleming | 25 | L | 10 | 8 | 5.09 | 26 | 11 | 0 | 0 | 15 | 1 | 1 | 104.1 | 110 | 60 | 59 | 11 | 31 | 65 | 0 | 0 | 3 | 1.35 | 9.49 | 0.95 | 2.67 | 5.61 | 5.18 | 2.10 | 2017- 5- 139-TBA | premium | premium | premium | MLB | 2020-2024 | 2017-2025 | 2021 |
| 64 | Joey Krehbiel | 28 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 1.00 | 0.00 | 0.00 | 9.00 | 18.00 | 0.00 | 2.00 | 2011- 12- 375-ANA | premium | premium | premium | MLB | 2018-2023 | 2011-2025 | 2021 |
| 8 | Jordan Luplow | 27 | R | 0 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2.00 | 18.00 | 9.00 | 0.00 | 0.00 | 9.00 | 0.00 | 2014- 3- 100-PIT | premium | premium | premium | MLB | 2017-2023 | 2012-2025 | 2021 |
| 35 | Brett Phillips | 27 | R | 0 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1.0 | 2 | 1 | 1 | 0 | 2 | 0 | 0 | 1 | 0 | 4.00 | 18.00 | 0.00 | 18.00 | 0.00 | 9.00 | 0.00 | 2012- 6- 189-HOU | premium | premium | premium | MLB | 2017-2023 | 2012-2025 | 2021 |
| 60 | Sean Poppen | 27 | R | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0.2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | 0.00 | 13.50 | 0.00 | 0.00 | 2016- 19- 573-MIN | premium | premium | premium | MLB | 2019-2022 | 2013-2025 | 2021 |
| 50 | Chaz Roe | 34 | R | 0 | 0 | 27.00 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0.2 | 1 | 2 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 3.00 | 13.50 | 0.00 | 13.50 | 27.00 | 27.00 | 2.00 | 2005- 1- 32-COL | premium | premium | premium | MLB | 2013-2021 | 2005-2021 | 2021 |
| Totals: | 100 | 62 | 3.67 | 693 | 162 | 1 | 0 | 161 | 531 | 42 | 1455.2 | 1264 | 651 | 594 | 184 | 436 | 1478 | 64 | 6 | 55 | 1.17 | 7.81 | 1.14 | 2.70 | 9.14 | 4.02 | 3.39 | premium | premium | premium |