| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 11 | Jorge Polanco | 27 | 2B | B | 111 | 152 | 588 | 97 | 158 | 35 | 2 | 33 | 98 | 11 | 6 | 45 | 118 | 5 | 0 | 6 | 0 | 4 | 296 | 644 | 70 | 88 | .269 | .323 | .503 | .826 | .320 | .234 | .282 | 6.99 | 18.32 | 2.62 | 17.82 | 2009- UDFA -MIN | premium | premium | premium | MLB | 2014-2025 | 2010-2025 | 2021 |
| 22 | Miguel Sano | 28 | 1B | R | 106 | 135 | 470 | 68 | 105 | 24 | 0 | 30 | 75 | 2 | 1 | 59 | 183 | 2 | 0 | 1 | 2 | 13 | 219 | 532 | 54 | 51 | .223 | .312 | .466 | .778 | .370 | .243 | .291 | 11.09 | 34.40 | 3.10 | 15.67 | 2009- UDFA -MIN | premium | premium | premium | MLB | 2015-2024 | 2010-2024 | 2021 |
| 20 | Josh Donaldson | 35 | 3B | R | 112 | 135 | 457 | 73 | 113 | 26 | 0 | 26 | 72 | 0 | 0 | 74 | 114 | 4 | 0 | 8 | 2 | 22 | 217 | 543 | 52 | 61 | .247 | .352 | .475 | .827 | .389 | .228 | .268 | 13.63 | 20.99 | 1.54 | 17.58 | 2007- 1- 48-CHN | premium | premium | premium | MLB | 2010-2023 | 2005-2023 | 2021 |
| 2 | Luis Arraez | 24 | 3B-2B | L | 101 | 121 | 428 | 58 | 126 | 17 | 6 | 2 | 42 | 2 | 2 | 43 | 48 | 2 | 0 | 6 | 2 | 9 | 161 | 479 | 25 | 101 | .294 | .357 | .376 | .733 | .182 | .082 | .323 | 8.98 | 10.02 | 1.12 | 214.00 | 2013- UDFA -MIN | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 26 | Max Kepler | 28 | RF | L | 99 | 121 | 426 | 61 | 90 | 21 | 4 | 19 | 54 | 10 | 0 | 54 | 96 | 6 | 0 | 4 | 3 | 2 | 176 | 490 | 44 | 46 | .211 | .306 | .413 | .719 | .352 | .202 | .225 | 11.02 | 19.59 | 1.78 | 22.42 | 2009- UDFA -MIN | premium | premium | premium | MLB | 2015-2025 | 2010-2025 | 2021 |
| 9 | Andrelton Simmons | 31 | SS | R | 80 | 131 | 412 | 37 | 92 | 12 | 0 | 3 | 31 | 1 | 0 | 32 | 62 | 3 | 3 | 1 | 0 | 14 | 113 | 451 | 15 | 77 | .223 | .283 | .274 | .557 | .131 | .051 | .256 | 7.10 | 13.75 | 1.94 | 137.33 | 2010- 2- 70-ATL | premium | premium | premium | MLB | 2012-2022 | 2010-2025 | 2021 |
| 23 | Nelson Cruz | 40 | DH | R | 111 | 85 | 296 | 44 | 87 | 13 | 1 | 19 | 50 | 3 | 0 | 35 | 63 | 5 | 0 | 7 | 6 | 10 | 159 | 343 | 33 | 54 | .294 | .370 | .537 | .907 | .372 | .243 | .308 | 10.20 | 18.37 | 1.80 | 15.58 | 1998- UDFA -NYN | premium | premium | premium | MLB | 2005-2023 | 2001-2023 | 2021 |
| 27 | Ryan Jeffers | 24 | C | R | 92 | 85 | 267 | 28 | 53 | 10 | 1 | 14 | 35 | 0 | 1 | 22 | 108 | 4 | 0 | 0 | 0 | 6 | 107 | 293 | 25 | 28 | .199 | .270 | .401 | .671 | .281 | .202 | .269 | 7.51 | 36.86 | 4.91 | 19.07 | 2018- 2- 59-MIN | premium | premium | premium | MLB | 2020-2025 | 2016-2025 | 2021 |
| 24 | Trevor Larnach | 24 | LF | L | 95 | 79 | 260 | 29 | 58 | 12 | 0 | 7 | 28 | 1 | 0 | 31 | 104 | 8 | 0 | 2 | 0 | 3 | 91 | 301 | 19 | 39 | .223 | .322 | .350 | .672 | .250 | .127 | .338 | 10.30 | 34.55 | 3.35 | 37.14 | 2018- 1- 20-MIN | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 |
| 25 | Byron Buxton | 27 | CF | R | 135 | 61 | 235 | 50 | 72 | 23 | 0 | 19 | 32 | 9 | 1 | 13 | 62 | 6 | 0 | 0 | 0 | 0 | 152 | 254 | 42 | 30 | .306 | .358 | .647 | 1.005 | .430 | .341 | .344 | 5.12 | 24.41 | 4.77 | 12.37 | 2012- 1- 2-MIN | premium | premium | premium | MLB | 2015-2025 | 2012-2025 | 2021 |
| 19 | Alex Kirilloff | 23 | 1B-RF | L | 97 | 59 | 215 | 23 | 54 | 11 | 1 | 8 | 34 | 1 | 1 | 14 | 52 | 1 | 0 | 1 | 2 | 3 | 91 | 231 | 20 | 34 | .251 | .299 | .423 | .722 | .237 | .172 | .295 | 6.06 | 22.51 | 3.71 | 26.88 | 2016- 1- 15-MIN | premium | premium | premium | MLB | 2021-2024 | 2016-2024 | 2021 |
| 64 | Willians Astudillo | 29 | 3B-1B | R | 87 | 72 | 208 | 17 | 49 | 8 | 0 | 7 | 21 | 0 | 0 | 3 | 12 | 4 | 0 | 1 | 0 | 12 | 78 | 216 | 15 | 34 | .236 | .259 | .375 | .634 | .154 | .139 | .221 | 1.39 | 5.56 | 4.00 | 29.71 | 2008- UDFA -PHI | premium | premium | premium | MLB | 2018-2022 | 2012-2024 | 2021 |
| 8 | Mitch Garver | 30 | C | R | 118 | 68 | 207 | 29 | 53 | 15 | 0 | 13 | 34 | 1 | 1 | 31 | 71 | 3 | 0 | 2 | 0 | 4 | 107 | 243 | 28 | 25 | .256 | .358 | .517 | .875 | .411 | .261 | .320 | 12.76 | 29.22 | 2.29 | 15.92 | 2013- 9- 260-MIN | premium | premium | premium | MLB | 2017-2025 | 2010-2025 | 2021 |
| 1 | Nick Gordon | 25 | CF-2B | L | 92 | 73 | 200 | 19 | 48 | 9 | 1 | 4 | 23 | 10 | 1 | 12 | 55 | 3 | 0 | 1 | 0 | 7 | 71 | 216 | 14 | 34 | .240 | .292 | .355 | .647 | .220 | .115 | .310 | 5.56 | 25.46 | 4.58 | 50.00 | 2014- 1- 5-MIN | premium | premium | premium | MLB | 2021-2024 | 2014-2025 | 2021 |
| 50 | Brent Rooker | 26 | LF | R | 96 | 58 | 189 | 25 | 38 | 10 | 0 | 9 | 16 | 0 | 0 | 15 | 70 | 9 | 0 | 0 | 0 | 1 | 75 | 213 | 19 | 19 | .201 | .291 | .397 | .688 | .275 | .196 | .264 | 7.04 | 32.86 | 4.67 | 21.00 | 2017- 1- 35-MIN | premium | premium | premium | MLB | 2020-2025 | 2015-2025 | 2021 |
| 60 | Jake Cave | 28 | LF-CF | L | 76* | 76 | 164 | 14 | 31 | 6 | 1 | 3 | 13 | 1 | 1 | 10 | 62 | 3 | 1 | 0 | 0 | 0 | 48 | 178 | 10 | 21 | .189 | .249 | .293 | .542 | .165 | .104 | .283 | 5.62 | 34.83 | 6.20 | 54.67 | 2011- 6- 209-NYA | premium | premium | premium | MLB | 2018-2024 | 2011-2024 | 2021 |
| 38 | Rob Refsnyder | 30 | CF-LF | R | 94* | 51 | 139 | 21 | 34 | 7 | 0 | 2 | 12 | 1 | 0 | 17 | 40 | 0 | 0 | 1 | 0 | 4 | 47 | 157 | 9 | 25 | .245 | .325 | .338 | .663 | .223 | .093 | .327 | 10.83 | 25.48 | 2.35 | 69.50 | 2012- 5- 187-NYA | premium | premium | premium | MLB | 2015-2025 | 2010-2025 | 2021 |
| 30 | Kyle Garlick | 29 | RF-LF | R | 101* | 36 | 99 | 17 | 23 | 8 | 0 | 5 | 10 | 1 | 0 | 6 | 32 | 1 | 0 | 1 | 0 | 2 | 46 | 107 | 13 | 10 | .232 | .280 | .465 | .745 | .303 | .233 | .286 | 5.61 | 29.91 | 5.33 | 19.80 | 2015- 28- 852-LAN | premium | premium | premium | MLB | 2019-2023 | 2011-2025 | 2021 |
| 70 | Ben Rortvedt | 23 | C | L | 39 | 89 | 8 | 15 | 1 | 0 | 3 | 7 | 0 | 0 | 6 | 29 | 1 | 2 | 0 | 0 | 2 | 25 | 98 | 4 | 11 | .169 | .229 | .281 | .510 | .180 | .112 | .211 | 6.12 | 29.59 | 4.83 | 29.67 | 2016- 2- 56-MIN | premium | premium | premium | MLB | 2021-2025 | 2016-2025 | 2021 | |
| 79 | Gilberto Celestino | 22 | CF | R | 23 | 59 | 7 | 8 | 3 | 0 | 2 | 3 | 0 | 0 | 3 | 14 | 0 | 0 | 0 | 0 | 2 | 17 | 62 | 5 | 3 | .136 | .177 | .288 | .465 | .203 | .152 | .140 | 4.84 | 22.58 | 4.67 | 29.50 | 2015- UDFA -HOU | premium | premium | premium | MLB | 2021-2022 | 2016-2025 | 2021 | |
| 15 | JT Riddle | 29 | SS | L | 4 | 6 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 2 | .333 | .333 | .333 | .666 | .000 | .000 | .333 | 0.00 | 0.00 | 0.00 | 0.00 | 2013- 13- 382-MIA | premium | premium | premium | MLB | 2017-2022 | 2011-2025 | 2021 | |
| 35 | Michael Pineda | 32 | P | R | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 33.33 | 0.00 | 0.00 | 2005- UDFA -SEA | premium | premium | premium | MLB | 2011-2022 | 2008-2022 | 2021 | |
| 83 | Griffin Jax | 26 | P | R | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 66.67 | 0.00 | 0.00 | 2016- 3- 93-MIN | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 | |
| 18 | Kenta Maeda | 33 | P | R | 4 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | .333 | .333 | .333 | .666 | .000 | .000 | .500 | 0.00 | 25.00 | 0.00 | 0.00 | 2016- UDFA -LAN | premium | premium | premium | MLB | 2016-2025 | 2008-2025 | 2021 | |
| 17 | Jose Berrios | 27 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2012- 1- 32-MIN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 82 | Bailey Ober | 25 | P | R | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | .500 | .500 | .500 | 1.000 | .000 | .000 | .500 | 0.00 | 0.00 | 0.00 | 0.00 | 2017- 12- 346-MIN | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 | |
| 74 | Joe Ryan | 25 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2018- 7- 210-TBA | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 | |
| 53 | Danny Coulombe | 31 | P | L | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2012- 25- 776-LAN | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 | |
| 85 | Charlie Barnes | 25 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2017- 4- 106-MIN | premium | premium | premium | MLB | 2021-2021 | 2015-2025 | 2021 | |
| Totals: | 1682 | 5431 | 729 | 1311 | 271 | 17 | 228 | 690 | 54 | 15 | 525 | 1405 | 70 | 7 | 42 | 17 | 122 | 2300 | 6075 | 516 | 795 | .241 | .314 | .423 | .738 | .286 | .182 | .282 | 8.64 | 23.13 | 2.68 | 23.82 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 33 | J.A. Happ | 38 | L | 5 | 6 | 6.77 | 19 | 19 | 0 | 0 | 0 | 0 | 0 | 98.1 | 125 | 76 | 74 | 21 | 31 | 77 | 3 | 0 | 3 | 1.59 | 11.44 | 1.92 | 2.84 | 7.05 | 6.96 | 2.48 | 2004- 3- 92-PHI | premium | premium | premium | MLB | 2007-2021 | 2002-2021 | 2021 |
| 82 | Bailey Ober | 25 | R | 3 | 3 | 4.19 | 20 | 20 | 0 | 0 | 0 | 0 | 0 | 92.1 | 92 | 45 | 43 | 20 | 19 | 96 | 1 | 0 | 1 | 1.20 | 8.97 | 1.95 | 1.85 | 9.36 | 4.39 | 5.05 | 2017- 12- 346-MIN | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 37 | Beau Burrows | 24 | R | 0 | 1 | 12.54 | 5 | 1 | 0 | 0 | 4 | 2 | 0 | 9.1 | 14 | 14 | 13 | 5 | 8 | 5 | 0 | 0 | 0 | 2.36 | 13.50 | 4.82 | 7.71 | 4.82 | 13.50 | 0.63 | 2015- 1- 22-DET | premium | premium | premium | MLB | 2020-2021 | 2015-2025 | 2021 |
| 83 | Griffin Jax | 26 | R | 4 | 5 | 6.37 | 18 | 14 | 0 | 0 | 4 | 2 | 0 | 82.0 | 82 | 62 | 58 | 23 | 29 | 65 | 6 | 0 | 5 | 1.35 | 9.00 | 2.52 | 3.18 | 7.13 | 6.80 | 2.24 | 2016- 3- 93-MIN | premium | premium | premium | MLB | 2021-2025 | 2014-2025 | 2021 |
| 64 | Shaun Anderson | 26 | R | 0 | 0 | 9.35 | 4 | 0 | 0 | 0 | 4 | 0 | 0 | 8.2 | 13 | 12 | 9 | 1 | 5 | 8 | 0 | 0 | 1 | 2.08 | 13.50 | 1.04 | 5.19 | 8.31 | 12.46 | 1.60 | 2016- 3- 88-BOS | premium | premium | premium | MLB | 2019-2025 | 2014-2025 | 2021 |
| 71 | Jovani Moran | 24 | L | 0 | 0 | 7.88 | 5 | 0 | 0 | 0 | 5 | 0 | 0 | 8.0 | 9 | 7 | 7 | 0 | 7 | 10 | 1 | 0 | 0 | 2.00 | 10.13 | 0.00 | 7.88 | 11.25 | 7.88 | 1.43 | 2015- 7- 200-MIN | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 48 | Alex Colome | 32 | R | 4 | 4 | 4.15 | 67 | 0 | 0 | 0 | 67 | 31 | 17 | 65.0 | 68 | 41 | 30 | 8 | 23 | 58 | 2 | 0 | 4 | 1.40 | 9.42 | 1.11 | 3.18 | 8.03 | 5.68 | 2.52 | 2007- UDFA -TBA | premium | premium | premium | MLB | 2013-2023 | 2008-2024 | 2021 |
| 56 | Caleb Thielbar | 34 | L | 7 | 0 | 3.23 | 59 | 0 | 0 | 0 | 59 | 14 | 0 | 64.0 | 55 | 24 | 23 | 8 | 20 | 77 | 3 | 0 | 3 | 1.17 | 7.73 | 1.13 | 2.81 | 10.83 | 3.38 | 3.85 | 2009- 18- 556-MIL | premium | premium | premium | MLB | 2013-2025 | 2006-2025 | 2021 |
| 21 | Tyler Duffey | 30 | R | 3 | 3 | 3.18 | 64 | 0 | 0 | 0 | 64 | 6 | 3 | 62.1 | 48 | 25 | 22 | 4 | 28 | 61 | 5 | 0 | 2 | 1.22 | 6.93 | 0.58 | 4.04 | 8.81 | 3.61 | 2.18 | 2012- 5- 160-MIN | premium | premium | premium | MLB | 2015-2024 | 2010-2025 | 2021 |
| 32 | Matt Shoemaker | 34 | R | 3 | 8 | 8.06 | 16 | 11 | 0 | 0 | 5 | 4 | 0 | 60.1 | 73 | 56 | 54 | 15 | 27 | 40 | 1 | 0 | 3 | 1.66 | 10.89 | 2.24 | 4.03 | 5.97 | 8.35 | 1.48 | 2008- UDFA -ANA | premium | premium | premium | MLB | 2013-2021 | 2006-2022 | 2021 |
| 65 | Ian Gibaut | 27 | R | 0 | 0 | 2.70 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 6.2 | 7 | 2 | 2 | 2 | 2 | 4 | 0 | 0 | 1 | 1.35 | 9.45 | 2.70 | 2.70 | 5.40 | 2.70 | 2.00 | 2015- 11- 328-TBA | premium | premium | premium | MLB | 2019-2025 | 2013-2025 | 2021 |
| 66 | Jorge Alcala | 25 | R | 3 | 6 | 3.92 | 59 | 0 | 0 | 0 | 59 | 15 | 1 | 59.2 | 45 | 29 | 26 | 10 | 13 | 61 | 1 | 1 | 2 | 0.97 | 6.79 | 1.51 | 1.96 | 9.20 | 4.37 | 4.69 | 2014- UDFA -HOU | premium | premium | premium | MLB | 2019-2025 | 2015-2025 | 2021 |
| 68 | Randy Dobnak | 26 | R | 1 | 7 | 7.64 | 14 | 6 | 0 | 0 | 8 | 3 | 1 | 50.2 | 66 | 44 | 43 | 11 | 12 | 27 | 2 | 0 | 1 | 1.54 | 11.72 | 1.95 | 2.13 | 4.80 | 7.82 | 2.25 | 2017- UDFA -MIN | premium | premium | premium | MLB | 2019-2025 | 2016-2025 | 2021 |
| 56 | Hansel Robles | 30 | R | 3 | 4 | 4.91 | 45 | 0 | 0 | 0 | 45 | 16 | 10 | 44.0 | 37 | 28 | 24 | 6 | 24 | 43 | 2 | 0 | 3 | 1.39 | 7.57 | 1.23 | 4.91 | 8.80 | 5.73 | 1.79 | 2008- UDFA -NYN | premium | premium | premium | MLB | 2015-2022 | 2010-2023 | 2021 |
| 55 | Taylor Rogers | 30 | L | 2 | 4 | 3.35 | 40 | 0 | 0 | 0 | 40 | 15 | 9 | 40.1 | 38 | 18 | 15 | 4 | 8 | 59 | 3 | 0 | 0 | 1.14 | 8.48 | 0.89 | 1.79 | 13.17 | 4.02 | 7.38 | 2012- 11- 340-MIN | premium | premium | premium | MLB | 2016-2025 | 2010-2025 | 2021 |
| 49 | Juan Minaya | 30 | R | 2 | 1 | 2.48 | 29 | 0 | 0 | 0 | 29 | 9 | 0 | 40.0 | 27 | 12 | 11 | 4 | 20 | 43 | 3 | 0 | 2 | 1.18 | 6.08 | 0.90 | 4.50 | 9.68 | 2.70 | 2.15 | 2008- UDFA -HOU | premium | premium | premium | MLB | 2016-2022 | 2009-2023 | 2021 |
| 31 | Devin Smeltzer | 25 | L | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 4.2 | 1 | 1 | 0 | 0 | 1 | 3 | 0 | 0 | 2 | 0.43 | 1.93 | 0.00 | 1.93 | 5.79 | 1.93 | 3.00 | 2016- 5- 161-LAN | premium | premium | premium | MLB | 2019-2023 | 2015-2025 | 2021 |
| 64 | Willians Astudillo | 29 | R | 0 | 0 | 2.25 | 4 | 0 | 0 | 0 | 4 | 4 | 0 | 4.0 | 1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0.75 | 2.25 | 2.25 | 4.50 | 0.00 | 2.25 | 0.00 | 2008- UDFA -PHI | premium | premium | premium | MLB | 2018-2022 | 2012-2024 | 2021 |
| 49 | Brandon Waddell | 27 | L | 0 | 1 | 11.25 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 4.0 | 10 | 6 | 5 | 2 | 3 | 1 | 0 | 0 | 0 | 3.25 | 22.50 | 4.50 | 6.75 | 2.25 | 13.50 | 0.33 | 2015- 5- 157-PIT | premium | premium | premium | MLB | 2020-2025 | 2013-2025 | 2021 |
| 85 | Charlie Barnes | 25 | L | 0 | 3 | 5.92 | 9 | 8 | 0 | 0 | 1 | 1 | 0 | 38.0 | 46 | 27 | 25 | 4 | 16 | 20 | 0 | 0 | 4 | 1.63 | 10.89 | 0.95 | 3.79 | 4.74 | 6.39 | 1.25 | 2017- 4- 106-MIN | premium | premium | premium | MLB | 2021-2021 | 2015-2025 | 2021 |
| 53 | Danny Coulombe | 31 | L | 3 | 2 | 3.67 | 29 | 1 | 0 | 0 | 28 | 13 | 0 | 34.1 | 35 | 17 | 14 | 5 | 7 | 33 | 0 | 0 | 0 | 1.22 | 9.17 | 1.31 | 1.83 | 8.65 | 4.46 | 4.71 | 2012- 25- 776-LAN | premium | premium | premium | MLB | 2014-2025 | 2009-2025 | 2021 |
| 33 | John Gant | 28 | R | 1 | 5 | 5.61 | 14 | 7 | 0 | 0 | 7 | 0 | 0 | 33.2 | 31 | 24 | 21 | 4 | 15 | 36 | 3 | 0 | 1 | 1.37 | 8.29 | 1.07 | 4.01 | 9.62 | 6.42 | 2.40 | 2011- 21- 642-NYN | premium | premium | premium | MLB | 2016-2021 | 2011-2025 | 2021 |
| 74 | Joe Ryan | 25 | R | 2 | 1 | 4.05 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 26.2 | 16 | 12 | 12 | 4 | 5 | 30 | 1 | 0 | 0 | 0.79 | 5.40 | 1.35 | 1.69 | 10.12 | 4.05 | 6.00 | 2018- 7- 210-TBA | premium | premium | premium | MLB | 2021-2025 | 2015-2025 | 2021 |
| 51 | Luke Farrell | 30 | R | 1 | 1 | 4.74 | 20 | 1 | 0 | 0 | 19 | 3 | 0 | 24.2 | 28 | 13 | 13 | 4 | 13 | 25 | 0 | 0 | 0 | 1.66 | 10.22 | 1.46 | 4.74 | 9.12 | 4.74 | 1.92 | 2013- 6- 174-KCA | premium | premium | premium | MLB | 2017-2022 | 2010-2024 | 2021 |
| 61 | Ralph Garza | 27 | R | 0 | 2 | 3.26 | 18 | 0 | 0 | 0 | 18 | 8 | 1 | 19.1 | 13 | 9 | 7 | 3 | 7 | 15 | 0 | 0 | 1 | 1.03 | 6.05 | 1.40 | 3.26 | 6.98 | 4.19 | 2.14 | 2015- 26- 769-HOU | premium | premium | premium | MLB | 2021-2022 | 2013-2025 | 2021 |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 77 | Andrew Albers | 35 | L | 1 | 2 | 7.58 | 5 | 3 | 0 | 0 | 2 | 2 | 0 | 19.0 | 24 | 16 | 16 | 9 | 9 | 12 | 0 | 1 | 1 | 1.74 | 11.37 | 4.26 | 4.26 | 5.68 | 7.58 | 1.33 | 2008- 10- 315-SDN | premium | premium | premium | MLB | 2013-2021 | 2005-2021 | 2021 |
| 61 | Cody Stashak | 27 | R | 0 | 0 | 6.89 | 15 | 0 | 0 | 0 | 15 | 1 | 0 | 15.2 | 16 | 12 | 12 | 2 | 10 | 26 | 1 | 0 | 1 | 1.66 | 9.19 | 1.15 | 5.74 | 14.94 | 6.89 | 2.60 | 2015- 13- 380-MIN | premium | premium | premium | MLB | 2019-2022 | 2015-2025 | 2021 |
| 43 | Lewis Thorpe | 25 | L | 0 | 2 | 4.70 | 5 | 4 | 0 | 0 | 1 | 1 | 0 | 15.1 | 14 | 11 | 8 | 2 | 7 | 6 | 1 | 0 | 0 | 1.37 | 8.22 | 1.17 | 4.11 | 3.52 | 6.46 | 0.86 | 2012- UDFA -MIN | premium | premium | premium | MLB | 2019-2021 | 2013-2025 | 2021 |
| 54 | Derek Law | 30 | R | 0 | 0 | 4.20 | 9 | 0 | 0 | 0 | 9 | 4 | 0 | 15.0 | 16 | 7 | 7 | 2 | 8 | 14 | 1 | 0 | 0 | 1.60 | 9.60 | 1.20 | 4.80 | 8.40 | 4.20 | 1.75 | 2011- 9- 297-SFN | premium | premium | premium | MLB | 2016-2024 | 2010-2025 | 2021 |
| 45 | Kyle Barraclough | 31 | R | 2 | 0 | 5.54 | 10 | 0 | 0 | 0 | 10 | 2 | 0 | 13.0 | 12 | 8 | 8 | 4 | 8 | 18 | 0 | 0 | 2 | 1.54 | 8.31 | 2.77 | 5.54 | 12.46 | 5.54 | 2.25 | 2012- 7- 240-SLN | premium | premium | premium | MLB | 2015-2023 | 2009-2025 | 2021 |
| 17 | Jose Berrios | 27 | R | 7 | 5 | 3.48 | 20 | 20 | 1 | 0 | 0 | 0 | 0 | 121.2 | 95 | 53 | 47 | 14 | 32 | 126 | 3 | 0 | 8 | 1.04 | 7.03 | 1.04 | 2.37 | 9.32 | 3.92 | 3.94 | 2012- 1- 32-MIN | premium | premium | premium | MLB | 2016-2025 | 2012-2025 | 2021 |
| 58 | Nick Vincent | 34 | R | 1 | 0 | 0.71 | 7 | 0 | 0 | 0 | 7 | 1 | 0 | 12.2 | 6 | 1 | 1 | 1 | 5 | 9 | 0 | 1 | 1 | 0.87 | 4.26 | 0.71 | 3.55 | 6.39 | 0.71 | 1.80 | 2008- 18- 555-SDN | premium | premium | premium | MLB | 2012-2021 | 2008-2022 | 2021 |
| 35 | Michael Pineda | 32 | R | 9 | 8 | 3.62 | 22 | 21 | 0 | 0 | 1 | 0 | 0 | 109.1 | 114 | 49 | 44 | 17 | 21 | 88 | 1 | 0 | 2 | 1.23 | 9.38 | 1.40 | 1.73 | 7.24 | 4.03 | 4.19 | 2005- UDFA -SEA | premium | premium | premium | MLB | 2011-2022 | 2008-2022 | 2021 |
| 18 | Kenta Maeda | 33 | R | 6 | 5 | 4.66 | 21 | 21 | 0 | 0 | 0 | 0 | 0 | 106.1 | 106 | 60 | 55 | 16 | 32 | 113 | 3 | 0 | 7 | 1.30 | 8.97 | 1.35 | 2.71 | 9.56 | 5.08 | 3.53 | 2016- UDFA -LAN | premium | premium | premium | MLB | 2016-2025 | 2008-2025 | 2021 |
| 52 | Edgar Garcia | 24 | R | 0 | 0 | 10.45 | 6 | 0 | 0 | 0 | 6 | 1 | 0 | 10.1 | 9 | 12 | 12 | 3 | 7 | 8 | 1 | 0 | 1 | 1.55 | 7.84 | 2.61 | 6.10 | 6.97 | 10.45 | 1.14 | 2014- UDFA -PHI | premium | premium | premium | MLB | 2019-2021 | 2014-2024 | 2021 |
| Totals: | 73 | 89 | 4.83 | 691 | 162 | 1 | 0 | 161 | 529 | 42 | 1419.1 | 1392 | 834 | 762 | 239 | 484 | 1317 | 48 | 3 | 62 | 1.32 | 8.83 | 1.52 | 3.07 | 8.35 | 5.29 | 2.72 | premium | premium | premium |