| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 8 | Christian Koss | 23 | SS | R | 103 | 104 | 428 | 65 | 116 | 18 | 7 | 15 | 55 | 10 | 4 | 31 | 100 | 5 | 0 | 4 | 0 | 4 | 193 | 468 | 40 | 76 | .271 | .325 | .451 | .776 | .266 | .180 | .319 | 6.62 | 21.37 | 3.23 | 28.53 | 2019- 12- 369-COL | premium | premium | premium | MLB | 2025-2025 | 2017-2025 | 2021 |
| 35 | Brandon Howlett | 21 | 3B | R | 109 | 96 | 360 | 62 | 91 | 19 | 4 | 17 | 57 | 2 | 0 | 44 | 136 | 8 | 0 | 2 | 1 | 5 | 169 | 414 | 40 | 51 | .253 | .345 | .469 | .814 | .344 | .216 | .354 | 10.63 | 32.85 | 3.09 | 21.18 | 2018- 21- 640-BOS | premium | premium | premium | AA | 2018-2022 | 2021 | |
| 24 | Tyler Dearden | 22 | LF | L | 117 | 97 | 352 | 73 | 92 | 20 | 0 | 24 | 80 | 1 | 0 | 55 | 114 | 7 | 0 | 4 | 1 | 7 | 184 | 418 | 44 | 48 | .261 | .368 | .523 | .891 | .420 | .262 | .312 | 13.16 | 27.27 | 2.07 | 14.67 | 2017- 29- 881-BOS | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 4 | Cam Cannon | 23 | 2B | R | 108 | 74 | 311 | 46 | 94 | 24 | 0 | 8 | 39 | 9 | 4 | 17 | 34 | 7 | 0 | 1 | 0 | 9 | 142 | 336 | 32 | 62 | .302 | .351 | .457 | .808 | .225 | .155 | .319 | 5.06 | 10.12 | 2.00 | 38.88 | 2019- 2- 43-BOS | premium | premium | premium | AAA | 2017-2024 | 2021 | |
| 25 | Tyler Esplin | 21 | CF | L | 81 | 78 | 297 | 42 | 60 | 14 | 1 | 2 | 30 | 4 | 0 | 38 | 90 | 2 | 0 | 1 | 0 | 4 | 82 | 338 | 17 | 43 | .202 | .296 | .276 | .572 | .215 | .074 | .282 | 11.24 | 26.63 | 2.37 | 148.50 | 2017- 7- 221-BOS | premium | premium | premium | AA | 2017-2023 | 2021 | |
| 9 | Nick Sogard | 23 | 2B-3B | B | 112 | 62 | 240 | 44 | 67 | 12 | 1 | 13 | 40 | 7 | 3 | 27 | 48 | 2 | 0 | 6 | 0 | 3 | 120 | 275 | 26 | 41 | .279 | .349 | .500 | .849 | .350 | .221 | .292 | 9.82 | 17.45 | 1.78 | 18.46 | 2019- 12- 368-TBA | premium | premium | premium | MLB | 2024-2025 | 2017-2025 | 2021 |
| 5 | Cole Brannen | 22 | RF-CF | L | 73 | 74 | 224 | 39 | 34 | 9 | 3 | 2 | 21 | 7 | 6 | 37 | 68 | 0 | 5 | 2 | 0 | 0 | 55 | 268 | 14 | 20 | .152 | .270 | .246 | .516 | .263 | .094 | .205 | 13.81 | 25.37 | 1.84 | 112.00 | 2017- 2- 63-BOS | premium | premium | premium | A+ | 2017-2025 | 2021 | |
| 26 | Wil Dalton | 23 | CF-RF | R | 82 | 60 | 214 | 30 | 39 | 11 | 1 | 7 | 29 | 1 | 2 | 23 | 67 | 1 | 1 | 1 | 0 | 2 | 73 | 240 | 19 | 20 | .182 | .264 | .341 | .605 | .262 | .159 | .227 | 9.58 | 27.92 | 2.91 | 30.57 | 2019- 8- 257-BOS | premium | premium | premium | AA | 2017-2022 | 2021 | |
| 34 | Joe Davis | 24 | 1B | R | 99 | 47 | 188 | 24 | 49 | 7 | 0 | 9 | 29 | 0 | 0 | 8 | 33 | 4 | 0 | 1 | 0 | 7 | 83 | 201 | 16 | 33 | .261 | .303 | .441 | .744 | .223 | .180 | .272 | 3.98 | 16.42 | 4.13 | 20.89 | 2019- 19- 587-BOS | premium | premium | premium | A+ | 2016-2022 | 2021 | |
| 38 | Tyreque Reed | 24 | 1B | R | 129 | 48 | 179 | 40 | 53 | 8 | 1 | 14 | 50 | 4 | 2 | 30 | 55 | 4 | 0 | 2 | 0 | 4 | 105 | 215 | 23 | 30 | .296 | .405 | .587 | .992 | .469 | .291 | .348 | 13.95 | 25.58 | 1.83 | 12.79 | 2017- 8- 254-TEX | premium | premium | premium | AA | 2017-2025 | 2021 | |
| 17 | Dominic D'Alessandro | 24 | 1B-LF | R | 87 | 51 | 179 | 21 | 39 | 6 | 1 | 6 | 22 | 0 | 0 | 13 | 70 | 5 | 0 | 2 | 1 | 5 | 65 | 199 | 13 | 26 | .218 | .286 | .363 | .649 | .218 | .145 | .314 | 6.53 | 35.18 | 5.38 | 29.83 | 2019- 22- 677-BOS | premium | premium | premium | A+ | 2017-2021 | 2021 | |
| 10 | Elih Marrero | 24 | C | B | 107 | 57 | 174 | 32 | 50 | 14 | 1 | 1 | 23 | 14 | 3 | 25 | 38 | 2 | 1 | 4 | 0 | 3 | 69 | 206 | 16 | 34 | .287 | .376 | .397 | .773 | .316 | .110 | .353 | 12.14 | 18.45 | 1.52 | 174.00 | 2018- 8- 250-BOS | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 9 | Kole Cottam | 24 | C | R | 116 | 46 | 156 | 22 | 43 | 13 | 1 | 6 | 24 | 0 | 0 | 25 | 64 | 5 | 1 | 3 | 0 | 3 | 76 | 190 | 20 | 23 | .276 | .386 | .487 | .873 | .372 | .211 | .416 | 13.16 | 33.68 | 2.56 | 26.00 | 2018- 4- 130-BOS | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 23 | Stephen Scott | 24 | RF-1B | L | 135 | 39 | 142 | 24 | 48 | 12 | 1 | 8 | 29 | 1 | 0 | 23 | 32 | 0 | 0 | 0 | 1 | 3 | 86 | 165 | 21 | 27 | .338 | .430 | .606 | 1.036 | .437 | .268 | .392 | 13.94 | 19.39 | 1.39 | 17.75 | 2019- 10- 317-BOS | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 1 | Jaxx Groshans | 22 | C | R | 102 | 34 | 122 | 13 | 32 | 6 | 3 | 4 | 16 | 0 | 0 | 9 | 28 | 1 | 0 | 1 | 0 | 6 | 56 | 133 | 13 | 19 | .262 | .316 | .459 | .775 | .270 | .197 | .308 | 6.77 | 21.05 | 3.11 | 30.50 | 2019- 5- 167-BOS | premium | premium | premium | AA | 2017-2025 | 2021 | |
| 26 | Devlin Granberg | 25 | 1B | R | 137* | 27 | 95 | 21 | 31 | 7 | 1 | 7 | 29 | 1 | 0 | 12 | 16 | 4 | 0 | 2 | 0 | 1 | 61 | 113 | 15 | 16 | .326 | .416 | .642 | 1.058 | .453 | .316 | .324 | 10.62 | 14.16 | 1.33 | 13.57 | 2018- 6- 190-BOS | premium | premium | premium | AAA | 2015-2022 | 2021 | |
| 4 | Nick Yorke | 19 | 2B | R | 128* | 21 | 84 | 17 | 28 | 6 | 1 | 4 | 15 | 2 | 1 | 11 | 22 | 0 | 0 | 1 | 0 | 2 | 48 | 96 | 11 | 17 | .333 | .406 | .571 | .977 | .381 | .238 | .407 | 11.46 | 22.92 | 2.00 | 21.00 | 2020- 1- 17-BOS | premium | premium | premium | MLB | 2024-2025 | 2021-2025 | 2021 |
| 11 | Jake MacKenzie | 22 | 2B-3B | R | 102* | 25 | 68 | 14 | 18 | 4 | 1 | 0 | 3 | 3 | 1 | 8 | 18 | 4 | 1 | 0 | 0 | 0 | 24 | 81 | 5 | 13 | .265 | .375 | .353 | .728 | .235 | .088 | .360 | 9.88 | 22.22 | 2.25 | 0.00 | 2020- UDFA -BOS | premium | premium | premium | A+ | 2018-2024 | 2021 | |
| 51 | Luke Bandy | 23 | CF | R | 53* | 19 | 67 | 5 | 7 | 1 | 0 | 1 | 4 | 2 | 0 | 7 | 41 | 0 | 0 | 1 | 0 | 2 | 11 | 75 | 2 | 5 | .104 | .187 | .164 | .351 | .194 | .060 | .231 | 9.33 | 54.67 | 5.86 | 67.00 | 2019- 29- 887-BOS | premium | premium | premium | A+ | 2017-2021 | 2021 | |
| 1 | Alan Marrero | 23 | C | R | 69* | 18 | 57 | 9 | 6 | 1 | 0 | 1 | 6 | 0 | 1 | 13 | 34 | 1 | 0 | 0 | 0 | 0 | 10 | 71 | 2 | 4 | .105 | .282 | .175 | .457 | .281 | .070 | .227 | 18.31 | 47.89 | 2.62 | 57.00 | 2016- 8- 238-BOS | premium | premium | premium | A+ | 2016-2025 | 2021 | |
| 18 | Dean Miller | 24 | RF-LF | R | 13 | 38 | 6 | 6 | 2 | 0 | 2 | 4 | 2 | 0 | 4 | 11 | 0 | 0 | 0 | 0 | 1 | 14 | 42 | 4 | 2 | .158 | .238 | .368 | .606 | .368 | .210 | .160 | 9.52 | 26.19 | 2.75 | 19.00 | 2019- 24- 737-BOS | premium | premium | premium | A+ | 2017-2024 | 2021 | ||
| 17 | Michael Osinski | 25 | 1B | R | 7 | 22 | 5 | 6 | 2 | 0 | 1 | 4 | 0 | 0 | 3 | 8 | 0 | 0 | 1 | 0 | 1 | 11 | 26 | 3 | 3 | .273 | .346 | .500 | .846 | .364 | .227 | .357 | 11.54 | 30.77 | 2.67 | 22.00 | 2017- 31- 941-BOS | premium | premium | premium | AAA | 2015-2021 | 2021 | ||
| - | Ricardo Cubillan | 23 | 3B-SS | B | 4 | 16 | 3 | 5 | 1 | 0 | 0 | 3 | 0 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 6 | 18 | 1 | 4 | .313 | .389 | .375 | .764 | .188 | .062 | .417 | 11.11 | 22.22 | 2.00 | 0.00 | 2014- UDFA -BOS | premium | premium | premium | AAA | 2016-2022 | 2021 | ||
| 6 | Danny Santana | 30 | SS-CF | B | 3 | 10 | 2 | 4 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | 8 | 11 | 2 | 2 | .400 | .364 | .800 | 1.164 | .400 | .400 | .429 | 0.00 | 27.27 | 0.00 | 10.00 | 2007- UDFA -MIN | premium | premium | premium | MLB | 2014-2021 | 2009-2025 | 2021 | |
| Totals: | 1104 | 4023 | 659 | 1018 | 218 | 28 | 153 | 614 | 70 | 27 | 465 | 1134 | 62 | 9 | 40 | 4 | 72 | 1751 | 4599 | 399 | 619 | .253 | .337 | .435 | .772 | .308 | .182 | .312 | 10.11 | 24.66 | 2.44 | 26.29 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 16 | Yusniel Padron-Artiles | 23 | R | 3 | 7 | 5.60 | 25 | 13 | 0 | 0 | 12 | 1 | 0 | 90.0 | 101 | 57 | 56 | 20 | 26 | 104 | 0 | 4 | 6 | 1.41 | 10.10 | 2.00 | 2.60 | 10.40 | 5.70 | 4.00 | 2018- 22- 670-BOS | premium | premium | premium | AA | 2018-2024 | 2021 | |
| 38 | Jeremy Wu-Yelland | 22 | L | 1 | 1 | 3.00 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 9.0 | 6 | 3 | 3 | 1 | 6 | 13 | 1 | 0 | 2 | 1.33 | 6.00 | 1.00 | 6.00 | 13.00 | 3.00 | 2.17 | 2020- 4- 118-BOS | premium | premium | premium | AA | 2020-2025 | 2021 | |
| 28 | Jay Groome | 22 | L | 3 | 8 | 5.29 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 81.2 | 76 | 52 | 48 | 12 | 32 | 108 | 7 | 0 | 4 | 1.32 | 8.38 | 1.32 | 3.53 | 11.90 | 5.73 | 3.38 | 2016- 1- 12-BOS | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| 33 | Brian Van Belle | 24 | R | 4 | 3 | 4.10 | 18 | 18 | 0 | 0 | 0 | 0 | 0 | 79.0 | 86 | 41 | 36 | 12 | 13 | 82 | 8 | 0 | 2 | 1.25 | 9.80 | 1.37 | 1.48 | 9.34 | 4.67 | 6.31 | 2020- UDFA -BOS | premium | premium | premium | MLB | 2025-2025 | 2018-2025 | 2021 |
| 36 | Rio Gomez | 26 | L | 0 | 0 | 4.70 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 7.2 | 10 | 4 | 4 | 1 | 1 | 10 | 0 | 0 | 0 | 1.43 | 11.74 | 1.17 | 1.17 | 11.74 | 4.70 | 10.00 | 2017- 36-1091-BOS | premium | premium | premium | AAA | 2014-2023 | 2021 | |
| 18 | Chris Murphy | 23 | L | 5 | 3 | 4.21 | 14 | 14 | 0 | 0 | 0 | 0 | 0 | 68.1 | 62 | 36 | 32 | 17 | 23 | 81 | 1 | 0 | 4 | 1.24 | 8.17 | 2.24 | 3.03 | 10.67 | 4.74 | 3.52 | 2019- 6- 197-BOS | premium | premium | premium | MLB | 2023-2025 | 2017-2025 | 2021 |
| 39 | Dylan Spacke | 23 | R | 4 | 2 | 3.07 | 29 | 4 | 0 | 0 | 25 | 1 | 0 | 67.1 | 63 | 24 | 23 | 7 | 22 | 83 | 2 | 1 | 4 | 1.26 | 8.42 | 0.94 | 2.94 | 11.09 | 3.21 | 3.77 | 2019- 21- 647-BOS | premium | premium | premium | AA | 2018-2023 | 2021 | |
| 37 | Brandon Walter | 24 | L | 4 | 3 | 3.70 | 12 | 12 | 0 | 0 | 0 | 0 | 0 | 58.1 | 46 | 35 | 24 | 6 | 14 | 86 | 9 | 0 | 5 | 1.03 | 7.10 | 0.93 | 2.16 | 13.27 | 5.40 | 6.14 | 2019- 26- 797-BOS | premium | premium | premium | MLB | 2023-2025 | 2016-2025 | 2021 |
| 19 | Yorvin Pantoja | 23 | L | 6 | 3 | 4.83 | 37 | 0 | 0 | 0 | 37 | 18 | 2 | 50.1 | 59 | 34 | 27 | 6 | 17 | 73 | 7 | 0 | 4 | 1.51 | 10.55 | 1.07 | 3.04 | 13.05 | 6.08 | 4.29 | 2014- UDFA -BOS | premium | premium | premium | AA | 2015-2025 | 2021 | |
| 20 | Jacob Wallace | 22 | R | 3 | 3 | 5.92 | 39 | 0 | 0 | 0 | 39 | 17 | 4 | 48.2 | 41 | 33 | 32 | 5 | 25 | 76 | 7 | 2 | 9 | 1.36 | 7.58 | 0.92 | 4.62 | 14.05 | 6.10 | 3.04 | 2019- 3- 100-COL | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 21 | Zach Bryant | 23 | R | 3 | 3 | 3.54 | 37 | 0 | 0 | 0 | 37 | 24 | 6 | 48.1 | 31 | 25 | 19 | 6 | 18 | 65 | 3 | 2 | 1 | 1.01 | 5.77 | 1.12 | 3.35 | 12.10 | 4.66 | 3.61 | 2019- 15- 462-CHN | premium | premium | premium | AA | 2017-2025 | 2021 | |
| 7 | Oddanier Mosqueda | 22 | L | 2 | 1 | 3.61 | 32 | 0 | 0 | 0 | 32 | 8 | 3 | 47.1 | 30 | 21 | 19 | 2 | 25 | 66 | 3 | 0 | 5 | 1.16 | 5.70 | 0.38 | 4.75 | 12.55 | 3.99 | 2.64 | 2015- UDFA -BOS | premium | premium | premium | AAA | 2016-2025 | 2021 | |
| 36 | Brendan Nail | 25 | L | 6 | 0 | 3.69 | 31 | 0 | 0 | 0 | 31 | 7 | 3 | 46.1 | 34 | 23 | 19 | 4 | 16 | 73 | 1 | 0 | 4 | 1.08 | 6.60 | 0.78 | 3.11 | 14.18 | 4.47 | 4.56 | 2017- UDFA -BOS | premium | premium | premium | AAA | 2015-2024 | 2021 | |
| 15 | Jose Espada | 24 | R | 2 | 0 | 3.09 | 28 | 2 | 0 | 0 | 26 | 9 | 0 | 43.2 | 32 | 17 | 15 | 9 | 16 | 53 | 2 | 0 | 1 | 1.10 | 6.60 | 1.85 | 3.30 | 10.92 | 3.50 | 3.31 | 2015- 5- 152-TOR | premium | premium | premium | MLB | 2023-2025 | 2015-2025 | 2021 |
| 22 | Brendan Cellucci | 23 | L | 2 | 3 | 5.30 | 36 | 0 | 0 | 0 | 36 | 11 | 0 | 37.1 | 36 | 24 | 22 | 3 | 28 | 59 | 5 | 2 | 1 | 1.71 | 8.68 | 0.72 | 6.75 | 14.22 | 5.79 | 2.11 | 2019- 12- 377-BOS | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 31 | Grant Gambrell | 23 | R | 1 | 6 | 7.16 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 32.2 | 44 | 29 | 26 | 8 | 14 | 38 | 2 | 0 | 5 | 1.78 | 12.12 | 2.20 | 3.86 | 10.47 | 7.99 | 2.71 | 2019- 3- 80-KCA | premium | premium | premium | AAA | 2017-2025 | 2021 | |
| 30 | Brayan Bello | 22 | R | 5 | 0 | 2.27 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 31.2 | 25 | 10 | 8 | 3 | 7 | 45 | 1 | 1 | 0 | 1.01 | 7.11 | 0.85 | 1.99 | 12.79 | 2.84 | 6.43 | 2017- UDFA -BOS | premium | premium | premium | MLB | 2022-2025 | 2018-2025 | 2021 |
| 44 | Jake Thompson | 26 | R | 0 | 0 | 8.10 | 3 | 0 | 0 | 0 | 3 | 0 | 0 | 3.1 | 8 | 6 | 3 | 0 | 3 | 3 | 1 | 0 | 0 | 3.30 | 21.60 | 0.00 | 8.10 | 8.10 | 16.20 | 1.00 | 2017- 4- 131-BOS | premium | premium | premium | AAA | 2014-2023 | 2021 | |
| 23 | Alex Scherff | 23 | R | 2 | 1 | 2.78 | 17 | 0 | 0 | 0 | 17 | 12 | 3 | 22.2 | 17 | 8 | 7 | 1 | 11 | 37 | 3 | 0 | 2 | 1.24 | 6.75 | 0.40 | 4.37 | 14.69 | 3.18 | 3.36 | 2017- 5- 161-BOS | premium | premium | premium | AAA | 2018-2025 | 2021 | |
| 6 | Cody Scroggins | 24 | R | 1 | 0 | 5.82 | 18 | 0 | 0 | 0 | 18 | 9 | 2 | 21.2 | 18 | 15 | 14 | 4 | 17 | 20 | 2 | 0 | 2 | 1.62 | 7.48 | 1.66 | 7.06 | 8.31 | 6.23 | 1.18 | 2019- 9- 287-BOS | premium | premium | premium | AAA | 2016-2024 | 2021 | |
| 48 | Casey Cobb | 25 | R | 2 | 0 | 1.35 | 6 | 0 | 0 | 0 | 6 | 2 | 0 | 20.0 | 14 | 3 | 3 | 2 | 3 | 24 | 0 | 0 | 1 | 0.85 | 6.30 | 0.90 | 1.35 | 10.80 | 1.35 | 8.00 | 2020- UDFA -BOS | premium | premium | premium | AA | 2017-2024 | 2021 | |
| 31 | Ryan Fernandez | 23 | R | 1 | 0 | 4.32 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 16.2 | 13 | 8 | 8 | 3 | 5 | 18 | 1 | 0 | 2 | 1.08 | 7.02 | 1.62 | 2.70 | 9.72 | 4.32 | 3.60 | 2018- 23- 700-BOS | premium | premium | premium | MLB | 2024-2025 | 2018-2025 | 2021 |
| 12 | Chase Shugart | 24 | R | 6 | 6 | 4.78 | 22 | 22 | 0 | 0 | 0 | 0 | 0 | 105.1 | 122 | 58 | 56 | 12 | 24 | 93 | 7 | 0 | 6 | 1.39 | 10.42 | 1.03 | 2.05 | 7.95 | 4.96 | 3.88 | 2018- 12- 370-BOS | premium | premium | premium | MLB | 2024-2025 | 2016-2025 | 2021 |
| 6 | Yasel Santana | 24 | R | 1 | 0 | 1.80 | 7 | 0 | 0 | 0 | 7 | 1 | 0 | 10.0 | 9 | 3 | 2 | 1 | 9 | 5 | 2 | 0 | 0 | 1.80 | 8.10 | 0.90 | 8.10 | 4.50 | 2.70 | 0.56 | 2017- UDFA -BOS | premium | premium | premium | A+ | 2017-2024 | 2021 | |
| Totals: | 67 | 53 | 4.35 | 456 | 120 | 0 | 0 | 120 | 336 | 23 | 1047.1 | 983 | 569 | 506 | 145 | 375 | 1315 | 75 | 12 | 70 | 1.30 | 8.45 | 1.25 | 3.22 | 11.30 | 4.89 | 3.51 | premium | premium | premium |