| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 51 | Ichiro Suzuki | 36 | RF | L | 105 | 162 | 680 | 74 | 214 | 30 | 3 | 6 | 43 | 42 | 9 | 45 | 86 | 3 | 3 | 1 | 13 | 3 | 268 | 732 | 39 | 175 | .315 | .359 | .394 | .753 | .194 | .079 | .353 | 6.15 | 11.75 | 1.91 | 113.33 | 2000- UDFA -SEA | premium | premium | premium | MLB | 2001-2019 | 1992-2019 | 2010 |
| 9 | Chone Figgins | 32 | 2B | B | 93 | 161 | 602 | 62 | 156 | 21 | 2 | 1 | 35 | 42 | 15 | 74 | 114 | 3 | 17 | 6 | 0 | 19 | 184 | 702 | 24 | 132 | .259 | .340 | .306 | .646 | .214 | .047 | .314 | 10.54 | 16.24 | 1.54 | 602.00 | 1997- 4- 132-COL | premium | premium | premium | MLB | 2002-2014 | 1997-2014 | 2010 |
| 4 | Jose Lopez | 26 | 3B | R | 84 | 150 | 593 | 49 | 142 | 29 | 0 | 10 | 58 | 3 | 2 | 23 | 66 | 3 | 0 | 3 | 1 | 20 | 201 | 622 | 39 | 103 | .239 | .270 | .339 | .609 | .140 | .100 | .254 | 3.70 | 10.61 | 2.87 | 59.30 | 2000- UDFA -SEA | premium | premium | premium | MLB | 2004-2012 | 2001-2020 | 2010 |
| 21 | Franklin Gutierrez | 27 | CF | R | 93 | 152 | 568 | 61 | 139 | 25 | 3 | 12 | 64 | 25 | 3 | 50 | 137 | 1 | 2 | 8 | 5 | 10 | 206 | 629 | 40 | 99 | .245 | .303 | .363 | .666 | .245 | .118 | .297 | 7.95 | 21.78 | 2.74 | 47.33 | 2000- UDFA -LAN | premium | premium | premium | MLB | 2005-2017 | 2001-2017 | 2010 |
| 13 | Casey Kotchman | 27 | 1B | L | 84 | 125 | 414 | 37 | 90 | 20 | 1 | 9 | 51 | 0 | 0 | 35 | 57 | 3 | 0 | 5 | 6 | 15 | 139 | 457 | 30 | 60 | .217 | .280 | .336 | .616 | .203 | .119 | .229 | 7.66 | 12.47 | 1.63 | 46.00 | 2001- 1- 13-ANA | premium | premium | premium | MLB | 2004-2013 | 2001-2016 | 2010 |
| 16 | Josh Wilson | 29 | SS | R | 82 | 108 | 361 | 22 | 82 | 14 | 2 | 2 | 25 | 5 | 0 | 14 | 74 | 12 | 0 | 1 | 0 | 6 | 106 | 388 | 18 | 64 | .227 | .278 | .294 | .572 | .119 | .067 | .280 | 3.61 | 19.07 | 5.29 | 180.50 | 1999- 3- 86-MIA | premium | premium | premium | MLB | 2005-2015 | 1999-2017 | 2010 |
| 55 | Michael Saunders | 23 | LF | L | 92 | 100 | 289 | 29 | 61 | 11 | 2 | 10 | 33 | 6 | 3 | 35 | 84 | 0 | 2 | 1 | 0 | 1 | 106 | 327 | 23 | 38 | .211 | .295 | .367 | .662 | .287 | .156 | .260 | 10.70 | 25.69 | 2.40 | 28.90 | 2004- 11- 333-SEA | premium | premium | premium | MLB | 2009-2017 | 2005-2018 | 2010 |
| 15 | Milton Bradley | 32 | LF-DH | B | 90 | 73 | 244 | 28 | 50 | 9 | 1 | 8 | 29 | 8 | 2 | 28 | 75 | 3 | 1 | 2 | 2 | 2 | 85 | 278 | 18 | 32 | .205 | .292 | .348 | .640 | .283 | .143 | .258 | 10.07 | 26.98 | 2.68 | 30.50 | 1996- 2- 40-MON | premium | premium | premium | MLB | 2000-2011 | 1996-2011 | 2010 |
| 10 | Adam Moore | 26 | C | R | 70 | 60 | 205 | 12 | 40 | 6 | 0 | 4 | 15 | 0 | 1 | 8 | 63 | 2 | 1 | 2 | 1 | 3 | 58 | 218 | 10 | 30 | .195 | .230 | .283 | .513 | .122 | .088 | .257 | 3.67 | 28.90 | 7.88 | 51.25 | 2006- 6- 171-SEA | premium | premium | premium | MLB | 2009-2018 | 2005-2019 | 2010 |
| 30 | Russell Branyan | 34 | DH | L | 109 | 57 | 205 | 23 | 44 | 10 | 0 | 15 | 33 | 1 | 0 | 30 | 82 | 2 | 0 | 1 | 2 | 4 | 99 | 238 | 25 | 19 | .215 | .319 | .483 | .802 | .420 | .268 | .266 | 12.61 | 34.45 | 2.73 | 13.67 | 1994- 7- 185-CLE | premium | premium | premium | MLB | 1998-2011 | 1994-2014 | 2010 |
| 2 | Jack Wilson | 32 | SS | R | 82 | 61 | 193 | 17 | 48 | 11 | 1 | 0 | 14 | 1 | 2 | 7 | 35 | 3 | 5 | 3 | 0 | 2 | 61 | 211 | 12 | 36 | .249 | .282 | .316 | .598 | .098 | .067 | .298 | 3.32 | 16.59 | 5.00 | 0.00 | 1998- 9- 258-SLN | premium | premium | premium | MLB | 2001-2012 | 1998-2012 | 2010 |
| 32 | Rob Johnson | 27 | C | R | 81 | 61 | 178 | 24 | 34 | 10 | 0 | 2 | 13 | 1 | 1 | 25 | 46 | 2 | 1 | 3 | 2 | 5 | 50 | 209 | 12 | 22 | .191 | .293 | .281 | .574 | .230 | .090 | .241 | 11.96 | 22.01 | 1.84 | 89.00 | 2004- 4- 123-SEA | premium | premium | premium | MLB | 2007-2013 | 2004-2013 | 2010 |
| 27 | Matt Tuiasosopo | 24 | LF-3B | R | 76* | 50 | 127 | 12 | 22 | 5 | 0 | 4 | 11 | 0 | 0 | 9 | 49 | 1 | 1 | 0 | 0 | 3 | 39 | 138 | 9 | 13 | .173 | .234 | .307 | .541 | .205 | .134 | .243 | 6.52 | 35.51 | 5.44 | 31.75 | 2004- 3- 93-SEA | premium | premium | premium | MLB | 2008-2016 | 2004-2018 | 2010 |
| 17 | Justin Smoak | 23 | 1B | B | 94 | 30 | 113 | 11 | 27 | 4 | 0 | 5 | 14 | 0 | 0 | 8 | 34 | 0 | 0 | 1 | 0 | 3 | 46 | 122 | 9 | 18 | .239 | .287 | .407 | .694 | .239 | .168 | .293 | 6.56 | 27.87 | 4.25 | 22.60 | 2008- 1- 11-TEX | premium | premium | premium | MLB | 2010-2020 | 2006-2021 | 2010 |
| 26 | Josh Bard | 32 | C | B | 88* | 39 | 112 | 9 | 24 | 7 | 0 | 3 | 10 | 0 | 0 | 10 | 27 | 0 | 3 | 1 | 0 | 4 | 40 | 126 | 10 | 14 | .214 | .276 | .357 | .633 | .232 | .143 | .253 | 7.94 | 21.43 | 2.70 | 37.33 | 1999- 3- 100-COL | premium | premium | premium | MLB | 2002-2011 | 1997-2012 | 2010 |
| 12 | Ryan Langerhans | 30 | LF | L | 96* | 60 | 107 | 16 | 21 | 2 | 1 | 3 | 4 | 4 | 1 | 24 | 51 | 0 | 1 | 0 | 1 | 0 | 34 | 132 | 6 | 15 | .196 | .344 | .318 | .662 | .374 | .122 | .340 | 18.18 | 38.64 | 2.13 | 35.67 | 1998- 3- 101-ATL | premium | premium | premium | MLB | 2002-2013 | 1998-2014 | 2010 |
| 5 | Mike Sweeney | 36 | DH | R | 106* | 30 | 99 | 11 | 26 | 3 | 0 | 6 | 18 | 2 | 0 | 9 | 14 | 1 | 0 | 1 | 0 | 3 | 47 | 110 | 9 | 17 | .263 | .327 | .475 | .802 | .323 | .212 | .250 | 8.18 | 12.73 | 1.56 | 16.50 | 1991- 10- 262-KCA | premium | premium | premium | MLB | 1995-2010 | 1991-2010 | 2010 |
| 24 | Ken Griffey | 40 | DH | L | 66* | 33 | 98 | 6 | 18 | 2 | 0 | 0 | 7 | 0 | 0 | 9 | 17 | 0 | 0 | 1 | 0 | 3 | 20 | 108 | 2 | 16 | .184 | .250 | .204 | .454 | .112 | .020 | .220 | 8.33 | 15.74 | 1.89 | 0.00 | 1987- 1- 1-SEA | premium | premium | premium | MLB | 1989-2010 | 1987-2010 | 2010 |
| 41 | Eliezer Alfonzo | 31 | C | R | 13 | 41 | 4 | 9 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 0 | 2 | 13 | 41 | 2 | 7 | .220 | .220 | .317 | .537 | .098 | .097 | .267 | 0.00 | 24.39 | 0.00 | 41.00 | 1996- UDFA -SLN | premium | premium | premium | MLB | 2006-2011 | 1997-2016 | 2010 | |
| 61 | Matt Mangini | 24 | 3B | L | 11 | 38 | 2 | 8 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 13 | 0 | 1 | 0 | 0 | 1 | 8 | 41 | 0 | 8 | .211 | .250 | .211 | .461 | .053 | .000 | .320 | 4.88 | 31.71 | 6.50 | 0.00 | 2007- 1- 52-SEA | premium | premium | premium | MLB | 2010-2010 | 2005-2012 | 2010 | |
| 20 | Mike Carp | 24 | 1B | L | 14 | 37 | 1 | 7 | 2 | 0 | 0 | 0 | 0 | 0 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 9 | 41 | 2 | 5 | .189 | .268 | .243 | .511 | .162 | .054 | .241 | 9.76 | 19.51 | 2.00 | 0.00 | 2004- 9- 254-NYN | premium | premium | premium | MLB | 2009-2014 | 2004-2019 | 2010 | |
| 1 | Eric Byrnes | 34 | LF | R | 15 | 32 | 1 | 3 | 2 | 0 | 0 | 0 | 1 | 0 | 6 | 9 | 0 | 0 | 0 | 0 | 1 | 5 | 38 | 2 | 1 | .094 | .237 | .156 | .393 | .281 | .062 | .130 | 15.79 | 23.68 | 1.50 | 0.00 | 1998- 8- 225-OAK | premium | premium | premium | MLB | 2000-2010 | 1995-2010 | 2010 | |
| 56 | Greg Halman | 22 | LF-CF | R | 9 | 29 | 1 | 4 | 1 | 0 | 0 | 3 | 1 | 0 | 1 | 11 | 0 | 0 | 0 | 0 | 0 | 5 | 30 | 1 | 3 | .138 | .167 | .172 | .339 | .103 | .034 | .222 | 3.33 | 36.67 | 11.00 | 0.00 | 2004- UDFA -SEA | premium | premium | premium | MLB | 2010-2011 | 2005-2011 | 2010 | |
| 6 | Chris Woodward | 34 | SS | R | 8 | 19 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 4 | 22 | 1 | 2 | .158 | .273 | .211 | .484 | .211 | .053 | .300 | 13.64 | 40.91 | 3.00 | 0.00 | 1994- 54-1438-TOR | premium | premium | premium | MLB | 1999-2011 | 1995-2012 | 2010 | |
| 40 | Guillermo Quiroz | 28 | C | R | 2 | 7 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 1 | 1 | .286 | .286 | .429 | .715 | .143 | .143 | .333 | 0.00 | 14.29 | 0.00 | 0.00 | 1998- UDFA -TOR | premium | premium | premium | MLB | 2004-2014 | 1999-2016 | 2010 | |
| # | player | age | pos | ba | tbc+ | g | ab | r | h | 2b | 3b | hr | rbi | sb | cs | bb | so | hbp | sh | sf | ibb | gdp | tb | pa | xbh | 1b | avg | obp | slg | ops | seca | iso | babip | bb% | so% | so/bb | ab/hr | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 38 | Jason Vargas | 27 | P | L | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 42.86 | 0.00 | 0.00 | 2004- 2- 68-MIA | premium | premium | premium | MLB | 2005-2019 | 2002-2019 | 2010 | |
| 18 | Ryan Rowland-Smith | 27 | P | L | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 75.00 | 0.00 | 0.00 | 2000- UDFA -SEA | premium | premium | premium | MLB | 2007-2014 | 2001-2014 | 2010 | |
| 36 | Cliff Lee | 31 | P | L | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 66.67 | 0.00 | 0.00 | 2000- 4- 105-MON | premium | premium | premium | MLB | 2002-2014 | 2000-2014 | 2010 | |
| 58 | Doug Fister | 26 | P | L | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2006- 7- 201-SEA | premium | premium | premium | MLB | 2009-2018 | 2005-2018 | 2010 | |
| 34 | Felix Hernandez | 24 | P | R | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 25.00 | 0.00 | 0.00 | 2002- UDFA -SEA | premium | premium | premium | MLB | 2005-2019 | 2003-2019 | 2010 | |
| 25 | Luke French | 24 | P | L | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 100.00 | 0.00 | 0.00 | 2004- 8- 223-DET | premium | premium | premium | MLB | 2009-2010 | 2004-2012 | 2010 | |
| 37 | Brian Sweeney | 36 | P | R | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | .000 | .000 | .000 | .000 | .000 | .000 | .000 | 0.00 | 0.00 | 0.00 | 0.00 | 1996- UDFA -SEA | premium | premium | premium | MLB | 2003-2010 | 1996-2013 | 2010 | |
| Totals: | 1594 | 5409 | 513 | 1274 | 227 | 16 | 101 | 485 | 142 | 39 | 459 | 1184 | 39 | 42 | 40 | 33 | 110 | 1836 | 5989 | 344 | 930 | .236 | .298 | .339 | .637 | .208 | .104 | .282 | 7.66 | 19.77 | 2.58 | 53.55 | premium | premium | premium |
| # | player | age | th | w | l | era | g | gs | cg | sho | gr | gf | sv | ip | h | r | er | hr | bb | so | wp | bk | hb | whip | h9 | hr9 | bb9 | so9 | ra9 | so/bb | draft info | status | cur-org | cur-lev | hilvl | mlb years | stat years | year |
| 39 | David Pauley | 27 | R | 4 | 9 | 4.07 | 19 | 15 | 0 | 0 | 4 | 2 | 0 | 90.2 | 89 | 44 | 41 | 13 | 30 | 51 | 4 | 0 | 4 | 1.31 | 8.83 | 1.29 | 2.98 | 5.06 | 4.37 | 1.70 | 2001- 8- 240-SDN | premium | premium | premium | MLB | 2006-2012 | 2001-2014 | 2010 |
| 33 | Chad Cordero | 28 | R | 0 | 1 | 6.52 | 9 | 0 | 0 | 0 | 9 | 4 | 0 | 9.2 | 10 | 7 | 7 | 1 | 5 | 6 | 1 | 0 | 1 | 1.55 | 9.31 | 0.93 | 4.66 | 5.59 | 6.52 | 1.20 | 2003- 1- 20-MON | premium | premium | premium | MLB | 2003-2010 | 2001-2013 | 2010 |
| 25 | Luke French | 24 | L | 5 | 7 | 4.83 | 16 | 13 | 0 | 0 | 3 | 2 | 0 | 87.2 | 88 | 47 | 47 | 13 | 29 | 37 | 4 | 0 | 4 | 1.33 | 9.03 | 1.33 | 2.98 | 3.80 | 4.83 | 1.28 | 2004- 8- 223-DET | premium | premium | premium | MLB | 2009-2010 | 2004-2012 | 2010 |
| 43 | Brandon League | 27 | R | 9 | 7 | 3.42 | 70 | 0 | 0 | 0 | 70 | 30 | 6 | 79.0 | 67 | 38 | 30 | 7 | 27 | 56 | 7 | 0 | 2 | 1.19 | 7.63 | 0.80 | 3.08 | 6.38 | 4.33 | 2.07 | 2001- 2- 59-TOR | premium | premium | premium | MLB | 2004-2014 | 2001-2017 | 2010 |
| 57 | Dan Cortes | 23 | R | 0 | 1 | 3.38 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 5.1 | 3 | 3 | 2 | 0 | 3 | 6 | 2 | 0 | 0 | 1.13 | 5.06 | 0.00 | 5.06 | 10.13 | 5.06 | 2.00 | 2005- 7- 215-CHA | premium | premium | premium | MLB | 2010-2011 | 2005-2014 | 2010 |
| 53 | David Aardsma | 28 | R | 0 | 6 | 3.44 | 53 | 0 | 0 | 0 | 53 | 43 | 31 | 49.2 | 33 | 19 | 19 | 5 | 25 | 49 | 2 | 0 | 2 | 1.17 | 5.98 | 0.91 | 4.53 | 8.88 | 3.44 | 1.96 | 2003- 1- 22-SFN | premium | premium | premium | MLB | 2004-2015 | 2001-2017 | 2010 |
| 35 | Ian Snell | 28 | R | 0 | 5 | 6.41 | 12 | 8 | 0 | 0 | 4 | 0 | 0 | 46.1 | 60 | 36 | 33 | 10 | 25 | 26 | 3 | 0 | 1 | 1.83 | 11.65 | 1.94 | 4.86 | 5.05 | 6.99 | 1.04 | 2000- 26- 779-PIT | premium | premium | premium | MLB | 2004-2010 | 2000-2013 | 2010 |
| 60 | Anthony Varvaro | 25 | R | 0 | 1 | 11.25 | 4 | 0 | 0 | 0 | 4 | 2 | 0 | 4.0 | 6 | 5 | 5 | 2 | 6 | 5 | 1 | 0 | 0 | 3.00 | 13.50 | 4.50 | 13.50 | 11.25 | 11.25 | 0.83 | 2005- 12- 353-SEA | premium | premium | premium | MLB | 2010-2015 | 2003-2016 | 2010 |
| 49 | Garrett Olson | 26 | L | 0 | 3 | 4.54 | 35 | 0 | 0 | 0 | 35 | 11 | 1 | 37.2 | 42 | 20 | 19 | 6 | 15 | 31 | 4 | 0 | 0 | 1.51 | 10.04 | 1.43 | 3.58 | 7.41 | 4.78 | 2.07 | 2005- 1- 48-BAL | premium | premium | premium | MLB | 2007-2012 | 2003-2012 | 2010 |
| 37 | Brian Sweeney | 36 | R | 1 | 2 | 3.16 | 24 | 0 | 0 | 0 | 24 | 8 | 0 | 37.0 | 33 | 16 | 13 | 5 | 6 | 14 | 2 | 0 | 0 | 1.05 | 8.03 | 1.22 | 1.46 | 3.41 | 3.89 | 2.33 | 1996- UDFA -SEA | premium | premium | premium | MLB | 2003-2010 | 1996-2013 | 2010 |
| 50 | Jamey Wright | 35 | R | 0 | 1 | 3.41 | 28 | 0 | 0 | 0 | 28 | 8 | 0 | 37.0 | 30 | 15 | 14 | 2 | 16 | 19 | 3 | 1 | 1 | 1.24 | 7.30 | 0.49 | 3.89 | 4.62 | 3.65 | 1.19 | 1993- 1- 28-COL | premium | premium | premium | MLB | 1996-2014 | 1993-2014 | 2010 |
| 46 | Sean White | 29 | R | 0 | 1 | 5.24 | 38 | 0 | 0 | 0 | 38 | 13 | 0 | 34.1 | 45 | 20 | 20 | 4 | 11 | 15 | 0 | 1 | 0 | 1.63 | 11.80 | 1.05 | 2.88 | 3.93 | 5.24 | 1.36 | 2003- 8- 247-ATL | premium | premium | premium | MLB | 2007-2010 | 2000-2013 | 2010 |
| 23 | Shawn Kelley | 26 | R | 3 | 1 | 3.96 | 22 | 0 | 0 | 0 | 22 | 7 | 0 | 25.0 | 26 | 11 | 11 | 5 | 12 | 26 | 0 | 0 | 1 | 1.52 | 9.36 | 1.80 | 4.32 | 9.36 | 3.96 | 2.17 | 2007- 13- 405-SEA | premium | premium | premium | MLB | 2009-2019 | 2003-2019 | 2010 |
| 34 | Felix Hernandez | 24 | R | 13 | 12 | 2.27 | 34 | 34 | 6 | 1 | 0 | 0 | 0 | 249.2 | 194 | 80 | 63 | 17 | 70 | 232 | 14 | 1 | 8 | 1.06 | 6.99 | 0.61 | 2.52 | 8.36 | 2.88 | 3.31 | 2002- UDFA -SEA | premium | premium | premium | MLB | 2005-2019 | 2003-2019 | 2010 |
| 52 | Chris Seddon | 26 | L | 1 | 0 | 5.64 | 14 | 0 | 0 | 0 | 14 | 5 | 0 | 22.1 | 21 | 14 | 14 | 4 | 10 | 16 | 2 | 0 | 0 | 1.39 | 8.46 | 1.61 | 4.03 | 6.45 | 5.64 | 1.60 | 2001- 5- 139-TBA | premium | premium | premium | MLB | 2007-2012 | 2001-2014 | 2010 |
| 38 | Jason Vargas | 27 | L | 9 | 12 | 3.78 | 31 | 31 | 0 | 0 | 0 | 0 | 0 | 192.2 | 187 | 86 | 81 | 18 | 54 | 116 | 1 | 4 | 1 | 1.25 | 8.74 | 0.84 | 2.52 | 5.42 | 4.02 | 2.15 | 2004- 2- 68-MIA | premium | premium | premium | MLB | 2005-2019 | 2002-2019 | 2010 |
| 54 | Kanekoa Texeira | 24 | R | 0 | 1 | 5.30 | 16 | 0 | 0 | 0 | 16 | 7 | 0 | 18.2 | 22 | 12 | 11 | 0 | 10 | 14 | 2 | 0 | 1 | 1.71 | 10.61 | 0.00 | 4.82 | 6.75 | 5.79 | 1.40 | 2006- 22- 675-CHA | premium | premium | premium | MLB | 2010-2011 | 2006-2016 | 2010 |
| 58 | Doug Fister | 26 | R | 6 | 14 | 4.11 | 28 | 28 | 0 | 0 | 0 | 0 | 0 | 171.0 | 187 | 85 | 78 | 13 | 32 | 93 | 8 | 3 | 6 | 1.28 | 9.84 | 0.68 | 1.68 | 4.89 | 4.47 | 2.91 | 2006- 7- 201-SEA | premium | premium | premium | MLB | 2009-2018 | 2005-2018 | 2010 |
| 37 | Jesus Colome | 32 | R | 0 | 1 | 5.29 | 12 | 0 | 0 | 0 | 12 | 1 | 0 | 17.0 | 15 | 10 | 10 | 1 | 11 | 16 | 3 | 0 | 1 | 1.53 | 7.94 | 0.53 | 5.82 | 8.47 | 5.29 | 1.45 | 1996- UDFA -OAK | premium | premium | premium | MLB | 2001-2010 | 1998-2015 | 2010 |
| 18 | Ryan Rowland-Smith | 27 | L | 1 | 10 | 6.75 | 27 | 20 | 0 | 0 | 7 | 2 | 0 | 109.1 | 141 | 94 | 82 | 25 | 44 | 49 | 7 | 0 | 7 | 1.69 | 11.61 | 2.06 | 3.62 | 4.03 | 7.74 | 1.11 | 2000- UDFA -SEA | premium | premium | premium | MLB | 2007-2014 | 2001-2014 | 2010 |
| 36 | Cliff Lee | 31 | L | 8 | 3 | 2.34 | 13 | 13 | 5 | 1 | 0 | 0 | 0 | 103.2 | 92 | 31 | 27 | 5 | 6 | 89 | 2 | 1 | 0 | 0.95 | 7.99 | 0.43 | 0.52 | 7.73 | 2.69 | 14.83 | 2000- 4- 105-MON | premium | premium | premium | MLB | 2002-2014 | 2000-2014 | 2010 |
| 57 | Mark Lowe | 27 | R | 1 | 3 | 3.48 | 11 | 0 | 0 | 0 | 11 | 4 | 0 | 10.1 | 11 | 5 | 4 | 1 | 5 | 7 | 1 | 0 | 0 | 1.55 | 9.58 | 0.87 | 4.35 | 6.10 | 4.35 | 1.40 | 2004- 5- 153-SEA | premium | premium | premium | MLB | 2006-2016 | 2002-2019 | 2010 |
| Totals: | 61 | 101 | 3.95 | 520 | 162 | 11 | 2 | 151 | 358 | 38 | 1438.0 | 1402 | 698 | 631 | 157 | 452 | 973 | 73 | 11 | 40 | 1.29 | 8.77 | 0.98 | 2.83 | 6.09 | 4.37 | 2.15 | premium | premium | premium |