| Central | W | L | Pct | GB |
| Detroit | 95 | 67 | .586 | -- |
| Cleveland | 80 | 82 | .494 | 15.0 |
| Chi White Sox | 79 | 83 | .488 | 16.0 |
| KC Royals | 71 | 91 | .438 | 24.0 |
| Minnesota | 63 | 99 | .389 | 32.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2011-04-01 | Carl Pavano | R | 35 | L 3-13 | @ TOR | 1 | 241 | L | 4.0 | 6 | 8 | 7 | 3 | 2 | 3 | 68 | 22 | 46 | 68% | 0-1 | 15.75 | 2.00 |
| 2011-04-02 | Francisco Liriano | L | 27 | L 1-6 | @ TOR | 1 | 90 | L | 4.1 | 4 | 4 | 4 | 2 | 5 | 3 | 95 | 48 | 47 | 49% | 0-1 | 9.00 | 2.25 |
| 2011-04-03 | Nick Blackburn | R | 29 | W 4-3 | @ TOR | 1 | 93 | W | 5.2 | 6 | 2 | 1 | 1 | 1 | 2 | 92 | 30 | 62 | 67% | 1-0 | 1.50 | 1.17 |
| 2011-04-04 | Scott Baker | R | 30 | L 3-4 | @ NYA | 1 | 139 | L | 6.0 | 5 | 4 | 4 | 2 | 4 | 4 | 96 | 39 | 57 | 59% | 0-1 | 6.00 | 1.50 |
| 2011-04-05 | Brian Duensing | L | 28 | W 5-4 | @ NYA | 1 | 23 | - | 7.0 | 6 | 4 | 4 | 2 | 2 | 7 | 103 | 38 | 65 | 63% | 0-0 | 5.14 | 1.14 |
| 2011-04-07 | Francisco Liriano | L | 27 | L 3-4 | @ NYA | 2 | 91 | L | 5.0 | 4 | 4 | 4 | 0 | 3 | 5 | 101 | 47 | 54 | 53% | 0-2 | 8.00 | 1.78 |
| 2011-04-08 | Carl Pavano | R | 35 | L 2-1 | vs OAK | 2 | 242 | W | 8.0 | 4 | 1 | 1 | 0 | 1 | 1 | 104 | 36 | 68 | 65% | 1-1 | 6.00 | 1.08 |
| 2011-04-09 | Nick Blackburn | R | 29 | W 0-1 | vs OAK | 2 | 94 | L | 6.0 | 6 | 1 | 0 | 0 | 3 | 2 | 106 | 41 | 65 | 61% | 1-1 | 0.75 | 1.33 |
| 2011-04-10 | Scott Baker | R | 30 | W 3-5 | vs OAK | 2 | 140 | L | 5.0 | 7 | 4 | 4 | 2 | 2 | 5 | 98 | 35 | 63 | 64% | 0-2 | 6.55 | 1.64 |
| 2011-04-12 | Brian Duensing | L | 28 | L 4-3 | vs KCA | 2 | 24 | - | 6.0 | 8 | 3 | 2 | 0 | 2 | 2 | 101 | 33 | 68 | 67% | 0-0 | 4.15 | 1.38 |
| 2011-04-13 | Francisco Liriano | L | 27 | W 5-10 | vs KCA | 3 | 92 | L | 5.0 | 8 | 7 | 7 | 0 | 1 | 4 | 75 | 25 | 50 | 67% | 0-3 | 9.64 | 1.79 |
| 2011-04-14 | Carl Pavano | R | 35 | L 3-4 | @ TBA | 3 | 243 | - | 8.0 | 4 | 0 | 0 | 0 | 2 | 7 | 106 | 40 | 66 | 62% | 1-1 | 3.60 | 0.95 |
| 2011-04-15 | Nick Blackburn | R | 29 | L 2-5 | @ TBA | 3 | 95 | L | 6.0 | 10 | 5 | 5 | 1 | 0 | 6 | 88 | 29 | 59 | 67% | 1-2 | 3.00 | 1.44 |
| 2011-04-16 | Scott Baker | R | 30 | L 3-4 | @ TBA | 3 | 141 | - | 7.0 | 4 | 1 | 1 | 0 | 1 | 6 | 94 | 29 | 65 | 69% | 0-2 | 4.50 | 1.28 |
| 2011-04-17 | Brian Duensing | L | 28 | W 4-2 | @ TBA | 3 | 25 | W | 7.0 | 7 | 2 | 2 | 0 | 2 | 5 | 111 | 43 | 68 | 61% | 1-0 | 3.60 | 1.35 |
| 2011-04-18 | Francisco Liriano | L | 27 | W 5-3 | @ BAL | 4 | 93 | W | 6.1 | 5 | 2 | 2 | 2 | 5 | 2 | 93 | 43 | 50 | 54% | 1-3 | 7.29 | 1.67 |
| 2011-04-19 | Carl Pavano | R | 35 | L 0-11 | @ BAL | 4 | 244 | L | 4.2 | 8 | 8 | 7 | 0 | 3 | 3 | 98 | 39 | 59 | 60% | 1-2 | 5.40 | 1.20 |
| 2011-04-20 | Nick Blackburn | R | 29 | L 4-5 | @ BAL | 4 | 96 | L | 7.0 | 7 | 5 | 5 | 2 | 1 | 4 | 91 | 31 | 60 | 66% | 1-3 | 3.96 | 1.36 |
| 2011-04-21 | Scott Baker | R | 30 | W 3-1 | @ BAL | 4 | 142 | W | 7.0 | 4 | 0 | 0 | 0 | 1 | 9 | 104 | 31 | 73 | 70% | 1-2 | 3.24 | 1.12 |
| 2011-04-23 | Brian Duensing | L | 28 | L 10-3 | vs CLE | 4 | 26 | W | 7.0 | 5 | 1 | 1 | 0 | 1 | 3 | 90 | 31 | 59 | 66% | 2-0 | 3.00 | 1.22 |
| 2011-04-24 | Carl Pavano | R | 35 | L 4-3 | vs CLE | 5 | 245 | W | 7.0 | 6 | 3 | 3 | 0 | 2 | 3 | 99 | 38 | 61 | 62% | 2-2 | 5.06 | 1.19 |
| 2011-04-27 | Francisco Liriano | L | 28 | W 2-8 | vs TBA | 5 | 94 | L | 3.0 | 6 | 7 | 7 | 0 | 4 | 4 | 83 | 38 | 45 | 54% | 1-4 | 9.00 | 1.88 |
| 2011-04-28 | Nick Blackburn | R | 29 | W 3-15 | vs TBA | 5 | 97 | L | 3.1 | 8 | 7 | 5 | 1 | 4 | 0 | 86 | 38 | 48 | 56% | 1-4 | 5.14 | 1.64 |
| 2011-04-28 | Anthony Swarzak | R | 26 | W 1-6 | vs TBA | 1 | 13 | L | 5.1 | 8 | 5 | 5 | 2 | 1 | 1 | 95 | 40 | 55 | 58% | 0-1 | 9.00 | 1.80 |
| 2011-04-29 | Scott Baker | R | 30 | L 3-4 | @ KCA | 5 | 143 | - | 6.1 | 8 | 2 | 2 | 0 | 1 | 2 | 104 | 35 | 69 | 66% | 1-2 | 3.19 | 1.19 |
| 2011-04-30 | Brian Duensing | L | 28 | L 2-11 | @ KCA | 5 | 27 | L | 7.0 | 8 | 3 | 2 | 1 | 2 | 6 | 98 | 38 | 60 | 61% | 2-1 | 2.91 | 1.26 |
| 2011-05-01 | Carl Pavano | R | 35 | L 3-10 | @ KCA | 6 | 246 | L | 5.1 | 12 | 7 | 6 | 1 | 0 | 0 | 88 | 33 | 55 | 63% | 2-3 | 5.84 | 1.35 |
| 2011-05-03 | Francisco Liriano | L | 28 | W 1-0 | @ CHA | 6 | 95 | W | 9.0 | 0 | 0 | 0 | 0 | 6 | 2 | 127 | 59 | 68 | 54% | 2-4 | 6.55 | 1.55 |
| 2011-05-04 | Nick Blackburn | R | 29 | W 3-2 | @ CHA | 6 | 98 | W | 6.2 | 4 | 1 | 1 | 1 | 4 | 1 | 107 | 43 | 64 | 60% | 2-4 | 4.37 | 1.54 |
| 2011-05-06 | Scott Baker | R | 30 | W 9-2 | @ BOS | 6 | 144 | W | 8.0 | 7 | 2 | 2 | 2 | 1 | 8 | 108 | 32 | 76 | 70% | 2-2 | 3.00 | 1.15 |
| 2011-05-07 | Brian Duensing | L | 28 | L 0-4 | @ BOS | 6 | 28 | L | 2.0 | 3 | 1 | 1 | 0 | 1 | 2 | 31 | 12 | 19 | 61% | 2-2 | 3.00 | 1.31 |
| 2011-05-08 | Carl Pavano | R | 35 | L 5-9 | @ BOS | 7 | 247 | L | 5.0 | 10 | 7 | 7 | 1 | 1 | 0 | 99 | 36 | 63 | 64% | 2-4 | 6.64 | 1.45 |
| 2011-05-09 | Nick Blackburn | R | 29 | L 1-2 | @ BOS | 7 | 99 | - | 6.1 | 7 | 1 | 1 | 0 | 3 | 5 | 109 | 41 | 68 | 62% | 2-4 | 3.95 | 1.56 |
| 2011-05-10 | Francisco Liriano | L | 28 | W 2-10 | vs DET | 7 | 96 | L | 3.0 | 3 | 4 | 4 | 1 | 3 | 1 | 59 | 30 | 29 | 49% | 2-5 | 7.00 | 1.58 |
| 2011-05-11 | Scott Baker | R | 30 | W 7-9 | vs DET | 7 | 145 | - | 4.1 | 6 | 5 | 5 | 1 | 5 | 6 | 98 | 35 | 63 | 64% | 2-2 | 3.68 | 1.27 |
| 2011-05-13 | Carl Pavano | R | 35 | W 0-2 | vs TOR | 8 | 248 | - | 5.1 | 7 | 0 | 0 | 0 | 3 | 1 | 115 | 44 | 71 | 62% | 2-4 | 5.94 | 1.51 |
| 2011-05-14 | Nick Blackburn | R | 29 | W 3-9 | vs TOR | 8 | 100 | - | 7.2 | 5 | 3 | 2 | 1 | 2 | 8 | 109 | 40 | 69 | 63% | 2-4 | 3.67 | 1.45 |
| 2011-05-15 | Brian Duensing | L | 28 | W 3-11 | vs TOR | 7 | 29 | L | 3.0 | 8 | 7 | 7 | 1 | 2 | 1 | 60 | 26 | 34 | 57% | 2-3 | 4.61 | 1.56 |
| 2011-05-16 | Scott Baker | R | 30 | L 2-5 | @ SEA | 8 | 146 | L | 6.0 | 7 | 4 | 4 | 2 | 2 | 8 | 107 | 37 | 70 | 65% | 2-3 | 3.96 | 1.30 |
| 2011-05-17 | Francisco Liriano | L | 28 | W 2-1 | @ SEA | 8 | 97 | W | 7.0 | 3 | 1 | 1 | 0 | 1 | 9 | 110 | 38 | 72 | 65% | 3-5 | 6.07 | 1.42 |
| 2011-05-18 | Carl Pavano | R | 35 | W 4-3 | @ OAK | 9 | 249 | - | 7.0 | 6 | 3 | 1 | 0 | 0 | 2 | 93 | 36 | 57 | 61% | 2-4 | 5.33 | 1.43 |
| 2011-05-19 | Nick Blackburn | R | 29 | W 11-1 | @ OAK | 9 | 101 | W | 7.0 | 5 | 1 | 1 | 0 | 2 | 1 | 98 | 37 | 61 | 62% | 3-4 | 3.38 | 1.39 |
| 2011-05-20 | Brian Duensing | L | 28 | L 7-8 | @ ARI | 8 | 30 | L | 6.0 | 7 | 5 | 5 | 1 | 1 | 5 | 86 | 27 | 59 | 69% | 2-4 | 4.98 | 1.53 |
| 2011-05-21 | Scott Baker | R | 30 | L 6-9 | @ ARI | 9 | 147 | - | 5.0 | 4 | 3 | 3 | 0 | 3 | 7 | 109 | 40 | 69 | 63% | 2-3 | 4.09 | 1.31 |
| 2011-05-22 | Francisco Liriano | L | 28 | L 2-3 | @ ARI | 9 | 98 | - | 6.0 | 6 | 2 | 2 | 1 | 4 | 4 | 104 | 50 | 54 | 52% | 3-5 | 5.69 | 1.45 |
| 2011-05-23 | Carl Pavano | R | 35 | W 7-8 | vs SEA | 10 | 250 | - | 7.0 | 9 | 4 | 4 | 1 | 2 | 3 | 108 | 36 | 72 | 67% | 2-4 | 5.31 | 1.44 |
| 2011-05-24 | Nick Blackburn | R | 29 | L 4-2 | vs SEA | 10 | 102 | W | 9.0 | 7 | 2 | 2 | 1 | 0 | 6 | 127 | 45 | 82 | 65% | 4-4 | 3.18 | 1.31 |
| 2011-05-25 | Brian Duensing | L | 28 | W 0-3 | vs SEA | 9 | 31 | L | 7.0 | 4 | 3 | 3 | 1 | 3 | 6 | 111 | 42 | 69 | 62% | 2-5 | 4.83 | 1.46 |
| 2011-05-27 | Scott Baker | R | 30 | W 5-6 | vs ANA | 10 | 148 | - | 7.0 | 6 | 0 | 0 | 0 | 0 | 6 | 105 | 28 | 77 | 73% | 2-3 | 3.63 | 1.26 |
| 2011-05-28 | Anthony Swarzak | R | 26 | L 1-0 | vs ANA | 2 | 14 | - | 8.0 | 1 | 0 | 0 | 0 | 2 | 4 | 105 | 37 | 68 | 65% | 0-2 | 3.60 | 1.07 |
| 2011-05-29 | Carl Pavano | R | 35 | W 5-6 | vs ANA | 11 | 251 | L | 8.0 | 10 | 5 | 4 | 0 | 0 | 3 | 113 | 33 | 80 | 71% | 2-5 | 5.22 | 1.42 |
| 2011-05-30 | Nick Blackburn | R | 29 | L 5-6 | @ DET | 11 | 103 | - | 6.0 | 7 | 5 | 5 | 2 | 1 | 3 | 100 | 37 | 63 | 63% | 4-4 | 3.55 | 1.31 |
| 2011-05-31 | Brian Duensing | L | 28 | L 7-8 | @ DET | 10 | 32 | - | 4.2 | 9 | 6 | 6 | 0 | 2 | 5 | 91 | 34 | 57 | 63% | 2-5 | 5.34 | 1.53 |
| 2011-06-01 | Scott Baker | R | 30 | L 2-4 | @ DET | 11 | 149 | L | 6.0 | 7 | 4 | 4 | 1 | 3 | 5 | 115 | 33 | 82 | 71% | 2-4 | 3.84 | 1.29 |
| 2011-06-02 | Anthony Swarzak | R | 26 | W 8-2 | @ KCA | 3 | 15 | W | 6.0 | 7 | 2 | 2 | 0 | 2 | 1 | 99 | 39 | 60 | 61% | 1-2 | 3.43 | 1.19 |
| 2011-06-03 | Carl Pavano | R | 35 | W 5-2 | @ KCA | 12 | 252 | W | 9.0 | 9 | 2 | 2 | 0 | 1 | 4 | 112 | 29 | 83 | 74% | 3-5 | 4.85 | 1.38 |
| 2011-06-04 | Nick Blackburn | R | 29 | W 7-2 | @ KCA | 12 | 104 | W | 5.0 | 7 | 2 | 2 | 0 | 1 | 2 | 79 | 27 | 52 | 66% | 5-4 | 3.55 | 1.33 |
| 2011-06-05 | Brian Duensing | L | 28 | W 6-0 | @ KCA | 11 | 33 | W | 8.0 | 6 | 0 | 0 | 0 | 1 | 4 | 115 | 45 | 70 | 61% | 3-5 | 4.70 | 1.45 |
| 2011-06-06 | Scott Baker | R | 30 | W 6-4 | @ CLE | 12 | 150 | W | 7.0 | 9 | 4 | 3 | 2 | 0 | 5 | 101 | 33 | 68 | 67% | 3-4 | 3.84 | 1.29 |
| 2011-06-07 | Francisco Liriano | L | 28 | L 0-1 | @ CLE | 10 | 99 | L | 5.0 | 3 | 1 | 0 | 0 | 3 | 7 | 85 | 36 | 49 | 58% | 3-6 | 5.17 | 1.43 |
| 2011-06-08 | Carl Pavano | R | 35 | W 3-2 | @ CLE | 13 | 253 | - | 7.0 | 7 | 1 | 1 | 1 | 1 | 3 | 110 | 39 | 71 | 65% | 3-5 | 4.55 | 1.36 |
| 2011-06-09 | Nick Blackburn | R | 29 | L 5-4 | vs TEX | 13 | 105 | - | 7.1 | 10 | 4 | 2 | 2 | 1 | 6 | 109 | 37 | 72 | 66% | 5-4 | 3.47 | 1.35 |
| 2011-06-10 | Brian Duensing | L | 28 | W 3-9 | vs TEX | 12 | 34 | L | 2.0 | 7 | 7 | 3 | 0 | 1 | 2 | 54 | 20 | 34 | 63% | 3-6 | 4.96 | 1.52 |
| 2011-06-11 | Scott Baker | R | 30 | L 8-1 | vs TEX | 13 | 151 | W | 9.0 | 5 | 1 | 1 | 0 | 0 | 7 | 112 | 32 | 80 | 71% | 4-4 | 3.54 | 1.21 |
| 2011-06-12 | Francisco Liriano | L | 28 | L 6-1 | vs TEX | 11 | 100 | W | 8.0 | 2 | 1 | 1 | 0 | 0 | 9 | 97 | 33 | 64 | 66% | 4-6 | 4.65 | 1.27 |
| 2011-06-15 | Carl Pavano | R | 35 | L 4-1 | vs CHA | 14 | 254 | W | 9.0 | 6 | 1 | 1 | 0 | 3 | 5 | 96 | 30 | 66 | 69% | 4-5 | 4.21 | 1.33 |
| 2011-06-16 | Nick Blackburn | R | 29 | L 1-0 | vs CHA | 14 | 106 | W | 8.0 | 7 | 0 | 0 | 0 | 1 | 1 | 95 | 27 | 68 | 72% | 6-4 | 3.16 | 1.32 |
| 2011-06-17 | Brian Duensing | L | 28 | L 6-5 | vs SDN | 13 | 35 | W | 6.0 | 7 | 2 | 2 | 0 | 1 | 5 | 104 | 37 | 67 | 64% | 4-6 | 4.80 | 1.51 |
| 2011-06-18 | Scott Baker | R | 30 | L 1-0 | vs SDN | 14 | 152 | W | 8.0 | 4 | 0 | 0 | 0 | 1 | 10 | 115 | 35 | 80 | 70% | 5-4 | 3.23 | 1.16 |
| 2011-06-19 | Francisco Liriano | L | 28 | L 5-4 | vs SDN | 12 | 101 | - | 7.0 | 8 | 3 | 3 | 0 | 2 | 8 | 100 | 41 | 59 | 59% | 4-6 | 4.57 | 1.29 |
| 2011-06-21 | Carl Pavano | R | 35 | W 9-2 | @ SFN | 15 | 255 | W | 8.0 | 9 | 2 | 2 | 1 | 0 | 2 | 106 | 32 | 74 | 70% | 5-5 | 4.06 | 1.31 |
| 2011-06-22 | Nick Blackburn | R | 29 | L 1-5 | @ SFN | 15 | 107 | L | 6.0 | 4 | 3 | 2 | 0 | 3 | 4 | 97 | 36 | 61 | 63% | 6-5 | 3.15 | 1.31 |
| 2011-06-23 | Brian Duensing | L | 28 | L 1-2 | @ SFN | 14 | 36 | L | 6.2 | 6 | 1 | 1 | 0 | 2 | 5 | 112 | 44 | 68 | 61% | 4-7 | 4.56 | 1.49 |
| 2011-06-24 | Scott Baker | R | 30 | L 3-4 | @ MIL | 15 | 153 | L | 6.2 | 8 | 4 | 4 | 0 | 4 | 4 | 97 | 35 | 62 | 64% | 5-5 | 3.40 | 1.21 |
| 2011-06-25 | Francisco Liriano | L | 28 | L 1-11 | @ MIL | 13 | 102 | L | 3.2 | 8 | 6 | 5 | 1 | 2 | 3 | 85 | 33 | 52 | 61% | 4-7 | 5.00 | 1.38 |
| 2011-06-26 | Carl Pavano | R | 35 | L 2-6 | @ MIL | 16 | 256 | L | 6.0 | 8 | 5 | 5 | 1 | 1 | 5 | 106 | 38 | 68 | 64% | 5-6 | 4.25 | 1.32 |
| 2011-06-27 | Nick Blackburn | R | 29 | W 0-15 | vs LAN | 16 | 108 | L | 4.1 | 13 | 8 | 7 | 1 | 1 | 1 | 72 | 25 | 47 | 65% | 6-6 | 3.65 | 1.40 |
| 2011-06-28 | Brian Duensing | L | 28 | L 6-4 | vs LAN | 15 | 37 | W | 5.0 | 4 | 4 | 4 | 1 | 4 | 3 | 95 | 37 | 58 | 61% | 5-7 | 4.71 | 1.50 |
| 2011-06-29 | Scott Baker | R | 30 | L 1-0 | vs LAN | 16 | 154 | W | 7.1 | 6 | 0 | 0 | 0 | 1 | 9 | 117 | 32 | 85 | 73% | 6-5 | 3.14 | 1.19 |
| 2011-07-01 | Francisco Liriano | L | 28 | L 6-2 | vs MIL | 14 | 103 | W | 7.0 | 4 | 2 | 2 | 1 | 2 | 7 | 104 | 41 | 63 | 61% | 5-7 | 4.78 | 1.33 |
| 2011-07-02 | Carl Pavano | R | 35 | W 7-8 | vs MIL | 17 | 257 | - | 7.2 | 8 | 4 | 3 | 1 | 0 | 4 | 105 | 31 | 74 | 70% | 5-6 | 4.19 | 1.30 |
| 2011-07-03 | Nick Blackburn | R | 29 | L 9-7 | vs MIL | 17 | 109 | - | 4.0 | 6 | 6 | 6 | 1 | 1 | 2 | 61 | 21 | 40 | 66% | 6-6 | 4.03 | 1.41 |
| 2011-07-04 | Brian Duensing | L | 28 | L 7-0 | vs TBA | 16 | 38 | W | 9.0 | 6 | 0 | 0 | 0 | 4 | 7 | 119 | 43 | 76 | 64% | 6-7 | 4.26 | 1.46 |
| 2011-07-05 | Scott Baker | R | 30 | L 3-2 | vs TBA | 17 | 155 | W | 5.0 | 3 | 1 | 0 | 0 | 1 | 3 | 62 | 18 | 44 | 71% | 7-5 | 3.00 | 1.17 |
| 2011-07-06 | Francisco Liriano | L | 28 | W 5-12 | vs TBA | 15 | 104 | - | 4.1 | 6 | 5 | 5 | 1 | 4 | 4 | 89 | 42 | 47 | 53% | 5-7 | 5.04 | 1.37 |
| 2011-07-07 | Carl Pavano | R | 35 | W 6-2 | @ CHA | 18 | 258 | W | 7.0 | 6 | 2 | 2 | 1 | 2 | 4 | 105 | 32 | 73 | 70% | 6-6 | 4.10 | 1.29 |
| 2011-07-08 | Nick Blackburn | R | 29 | W 8-5 | @ CHA | 18 | 110 | W | 5.0 | 10 | 5 | 5 | 1 | 2 | 4 | 107 | 41 | 66 | 62% | 7-6 | 4.25 | 1.45 |
| 2011-07-09 | Brian Duensing | L | 28 | L 3-4 | @ CHA | 17 | 39 | - | 7.0 | 5 | 2 | 2 | 1 | 1 | 2 | 101 | 37 | 64 | 63% | 6-7 | 4.15 | 1.42 |
| 2011-07-10 | Anthony Swarzak | R | 26 | W 6-3 | @ CHA | 4 | 16 | W | 6.0 | 4 | 1 | 1 | 0 | 2 | 5 | 92 | 29 | 63 | 68% | 2-2 | 3.38 | 1.28 |
| 2011-07-14 | Francisco Liriano | L | 28 | L 8-4 | vs KCA | 16 | 105 | W | 7.0 | 7 | 3 | 1 | 0 | 2 | 4 | 105 | 42 | 63 | 60% | 6-7 | 4.75 | 1.36 |
| 2011-07-15 | Nick Blackburn | R | 29 | W 1-2 | vs KCA | 19 | 111 | - | 7.0 | 4 | 0 | 0 | 0 | 2 | 3 | 96 | 39 | 57 | 59% | 7-6 | 4.00 | 1.42 |
| 2011-07-16 | Carl Pavano | R | 36 | L 4-3 | vs KCA | 19 | 259 | - | 7.0 | 6 | 3 | 3 | 1 | 1 | 3 | 96 | 31 | 65 | 68% | 6-6 | 4.08 | 1.28 |
| 2011-07-17 | Brian Duensing | L | 28 | L 4-3 | vs KCA | 18 | 40 | W | 6.1 | 7 | 3 | 3 | 1 | 0 | 2 | 96 | 37 | 59 | 61% | 7-7 | 4.13 | 1.39 |
| 2011-07-18 | Anthony Swarzak | R | 26 | W 2-5 | vs CLE | 5 | 17 | L | 6.0 | 6 | 4 | 3 | 1 | 0 | 4 | 95 | 35 | 60 | 63% | 2-3 | 3.52 | 1.24 |
| 2011-07-18 | Scott Diamond | L | 25 | W 3-6 | vs CLE | 1 | 1 | L | 6.1 | 7 | 4 | 3 | 1 | 2 | 1 | 90 | 34 | 56 | 62% | 0-1 | 4.50 | 1.50 |
| 2011-07-19 | Francisco Liriano | L | 28 | L 2-1 | vs CLE | 17 | 106 | - | 6.0 | 4 | 1 | 1 | 0 | 4 | 5 | 99 | 45 | 54 | 55% | 6-7 | 4.55 | 1.36 |
| 2011-07-20 | Nick Blackburn | R | 29 | L 7-5 | vs CLE | 20 | 112 | - | 6.0 | 4 | 4 | 1 | 0 | 2 | 7 | 103 | 39 | 64 | 62% | 7-6 | 3.88 | 1.40 |
| 2011-07-21 | Carl Pavano | R | 36 | W 2-6 | vs DET | 20 | 260 | L | 6.0 | 9 | 5 | 5 | 1 | 1 | 2 | 103 | 29 | 74 | 72% | 6-7 | 4.24 | 1.29 |
| 2011-07-22 | Brian Duensing | L | 28 | W 2-8 | vs DET | 19 | 41 | L | 4.2 | 9 | 7 | 7 | 2 | 1 | 7 | 96 | 37 | 59 | 61% | 7-8 | 4.54 | 1.43 |
| 2011-07-23 | Scott Baker | R | 30 | L 4-1 | vs DET | 18 | 156 | W | 5.0 | 3 | 0 | 0 | 0 | 1 | 5 | 82 | 27 | 55 | 67% | 8-5 | 2.87 | 1.16 |
| 2011-07-24 | Francisco Liriano | L | 28 | W 2-5 | vs DET | 18 | 107 | L | 2.1 | 6 | 4 | 4 | 0 | 4 | 3 | 78 | 35 | 43 | 55% | 6-8 | 4.82 | 1.43 |
| 2011-07-25 | Nick Blackburn | R | 29 | L 6-20 | @ TEX | 21 | 113 | L | 2.2 | 11 | 9 | 6 | 2 | 0 | 0 | 67 | 22 | 45 | 67% | 7-7 | 4.21 | 1.45 |
| 2011-07-26 | Carl Pavano | R | 36 | W 9-8 | @ TEX | 21 | 261 | - | 5.0 | 9 | 8 | 8 | 1 | 2 | 1 | 107 | 44 | 63 | 59% | 6-7 | 4.60 | 1.33 |
| 2011-07-27 | Brian Duensing | L | 28 | W 7-2 | @ TEX | 20 | 42 | W | 6.2 | 7 | 1 | 1 | 0 | 1 | 6 | 114 | 45 | 69 | 61% | 8-8 | 4.35 | 1.42 |
| 2011-07-28 | Scott Baker | R | 30 | L 1-4 | @ TEX | 19 | 157 | L | 7.0 | 8 | 2 | 2 | 0 | 0 | 4 | 103 | 35 | 68 | 66% | 8-6 | 2.85 | 1.15 |
| 2011-07-29 | Francisco Liriano | L | 28 | W 9-5 | @ OAK | 19 | 108 | W | 7.0 | 6 | 2 | 2 | 1 | 2 | 4 | 102 | 46 | 56 | 55% | 7-8 | 4.67 | 1.42 |
| 2011-07-30 | Nick Blackburn | R | 29 | L 3-8 | @ OAK | 22 | 114 | L | 4.1 | 10 | 7 | 6 | 0 | 5 | 2 | 97 | 44 | 53 | 55% | 7-8 | 4.50 | 1.52 |
| 2011-07-31 | Carl Pavano | R | 36 | L 3-7 | @ OAK | 22 | 262 | L | 4.0 | 9 | 7 | 7 | 0 | 2 | 1 | 97 | 31 | 66 | 68% | 6-8 | 4.90 | 1.37 |
| 2011-08-02 | Brian Duensing | L | 28 | L 1-5 | @ ANA | 21 | 43 | L | 6.0 | 8 | 5 | 5 | 2 | 2 | 3 | 97 | 38 | 59 | 61% | 8-9 | 4.50 | 1.43 |
| 2011-08-03 | Scott Baker | R | 30 | W 11-4 | @ ANA | 20 | 158 | - | 3.0 | 5 | 4 | 3 | 1 | 1 | 2 | 80 | 23 | 57 | 71% | 8-6 | 3.00 | 1.17 |
| 2011-08-04 | Francisco Liriano | L | 28 | L 1-7 | @ ANA | 20 | 109 | L | 5.0 | 10 | 7 | 7 | 1 | 2 | 5 | 96 | 38 | 58 | 60% | 7-9 | 5.03 | 1.46 |
| 2011-08-05 | Nick Blackburn | R | 29 | W 3-5 | vs CHA | 23 | 115 | L | 5.1 | 7 | 4 | 4 | 2 | 6 | 1 | 89 | 41 | 48 | 54% | 7-9 | 4.57 | 1.55 |
| 2011-08-06 | Carl Pavano | R | 36 | W 1-6 | vs CHA | 23 | 263 | L | 8.0 | 9 | 2 | 1 | 0 | 1 | 5 | 112 | 36 | 76 | 68% | 6-9 | 4.71 | 1.36 |
| 2011-08-07 | Brian Duensing | L | 28 | W 0-7 | vs CHA | 22 | 44 | L | 6.1 | 9 | 5 | 4 | 2 | 1 | 4 | 104 | 41 | 63 | 61% | 8-10 | 4.57 | 1.44 |
| 2011-08-08 | Scott Baker | R | 30 | W 6-8 | vs BOS | 21 | 159 | - | 6.0 | 9 | 5 | 5 | 2 | 0 | 5 | 93 | 27 | 66 | 71% | 8-6 | 3.20 | 1.19 |
| 2011-08-09 | Francisco Liriano | L | 28 | W 3-4 | vs BOS | 21 | 110 | - | 6.0 | 4 | 3 | 3 | 1 | 7 | 4 | 109 | 56 | 53 | 49% | 7-9 | 5.00 | 1.48 |
| 2011-08-10 | Nick Blackburn | R | 29 | L 5-2 | vs BOS | 24 | 116 | - | 6.2 | 6 | 1 | 0 | 0 | 2 | 4 | 108 | 39 | 69 | 64% | 7-9 | 4.37 | 1.54 |
| 2011-08-12 | Carl Pavano | R | 36 | L 2-3 | @ CLE | 24 | 264 | - | 7.1 | 10 | 2 | 1 | 0 | 0 | 4 | 105 | 25 | 80 | 76% | 6-9 | 4.56 | 1.36 |
| 2011-08-13 | Brian Duensing | L | 28 | L 1-3 | @ CLE | 23 | 45 | L | 6.2 | 9 | 3 | 3 | 1 | 2 | 9 | 115 | 40 | 75 | 65% | 8-11 | 4.53 | 1.45 |
| 2011-08-15 | Francisco Liriano | L | 28 | W 9-6 | @ DET | 22 | 111 | W | 6.0 | 9 | 5 | 5 | 2 | 1 | 4 | 94 | 35 | 59 | 63% | 8-9 | 5.12 | 1.49 |
| 2011-08-16 | Nick Blackburn | R | 29 | L 1-7 | @ DET | 25 | 117 | L | 4.2 | 11 | 5 | 5 | 0 | 2 | 1 | 103 | 39 | 64 | 62% | 7-10 | 4.53 | 1.58 |
| 2011-08-17 | Carl Pavano | R | 36 | W 6-5 | @ DET | 25 | 265 | - | 7.0 | 9 | 3 | 3 | 1 | 2 | 4 | 105 | 36 | 69 | 66% | 6-9 | 4.53 | 1.37 |
| 2011-08-18 | Brian Duensing | L | 28 | W 4-8 | vs NYA | 24 | 46 | L | 5.0 | 10 | 6 | 6 | 3 | 1 | 1 | 91 | 34 | 57 | 63% | 8-12 | 4.75 | 1.47 |
| 2011-08-19 | Kevin Slowey | R | 27 | W 1-8 | vs NYA | 1 | 83 | L | 5.2 | 9 | 6 | 6 | 2 | 1 | 4 | 102 | 27 | 75 | 74% | 0-1 | 6.30 | 1.50 |
| 2011-08-20 | Francisco Liriano | L | 28 | L 9-4 | vs NYA | 23 | 112 | W | 7.0 | 3 | 1 | 0 | 0 | 3 | 6 | 107 | 44 | 63 | 59% | 9-9 | 4.85 | 1.45 |
| 2011-08-21 | Nick Blackburn | R | 29 | W 0-3 | vs NYA | 26 | 118 | - | 1.1 | 1 | 0 | 0 | 0 | 4 | 0 | 49 | 26 | 23 | 47% | 7-10 | 4.50 | 1.60 |
| 2011-08-22 | Carl Pavano | R | 36 | W 1-4 | vs BAL | 26 | 266 | L | 7.0 | 9 | 4 | 4 | 2 | 2 | 3 | 116 | 39 | 77 | 66% | 6-10 | 4.55 | 1.38 |
| 2011-08-23 | Brian Duensing | L | 28 | W 1-8 | vs BAL | 25 | 47 | L | 2.0 | 9 | 7 | 7 | 1 | 1 | 2 | 66 | 26 | 40 | 61% | 8-13 | 5.12 | 1.52 |
| 2011-08-24 | Kevin Slowey | R | 27 | W 1-6 | vs BAL | 2 | 84 | L | 4.2 | 7 | 5 | 5 | 1 | 1 | 3 | 89 | 30 | 59 | 66% | 0-2 | 6.84 | 1.52 |
| 2011-08-25 | Francisco Liriano | L | 28 | W 1-6 | vs BAL | 24 | 113 | - | 2.0 | 2 | 1 | 1 | 0 | 3 | 2 | 42 | 19 | 23 | 55% | 9-9 | 4.84 | 1.47 |
| 2011-08-26 | Scott Diamond | L | 25 | W 1-8 | vs DET | 2 | 2 | L | 6.1 | 10 | 5 | 4 | 0 | 1 | 3 | 91 | 28 | 63 | 69% | 0-2 | 4.85 | 1.54 |
| 2011-08-27 | Carl Pavano | R | 36 | W 4-6 | vs DET | 27 | 267 | L | 6.2 | 9 | 6 | 5 | 2 | 1 | 4 | 100 | 38 | 62 | 62% | 6-11 | 4.62 | 1.38 |
| 2011-08-28 | Brian Duensing | L | 29 | L 11-4 | vs DET | 26 | 48 | W | 6.0 | 7 | 4 | 3 | 0 | 3 | 4 | 91 | 36 | 55 | 60% | 9-13 | 5.09 | 1.53 |
| 2011-08-29 | Kevin Slowey | R | 27 | L 0-3 | @ CHA | 3 | 85 | L | 7.0 | 6 | 2 | 2 | 0 | 2 | 3 | 94 | 30 | 64 | 68% | 0-3 | 5.91 | 1.44 |
| 2011-08-30 | Anthony Swarzak | R | 26 | L 6-8 | @ CHA | 6 | 18 | L | 4.1 | 6 | 8 | 6 | 1 | 1 | 1 | 79 | 24 | 55 | 70% | 3-5 | 4.14 | 1.28 |
| 2011-08-31 | Scott Diamond | L | 25 | W 7-6 | @ CHA | 3 | 3 | W | 6.0 | 3 | 3 | 3 | 1 | 3 | 5 | 90 | 35 | 55 | 61% | 1-2 | 4.74 | 1.37 |
| 2011-09-02 | Carl Pavano | R | 36 | W 13-5 | @ ANA | 28 | 268 | W | 6.2 | 7 | 4 | 3 | 0 | 0 | 4 | 118 | 35 | 83 | 70% | 7-11 | 4.60 | 1.37 |
| 2011-09-03 | Brian Duensing | L | 29 | L 6-10 | @ ANA | 27 | 49 | - | 1.1 | 3 | 5 | 5 | 1 | 2 | 0 | 35 | 16 | 19 | 54% | 9-13 | 5.35 | 1.55 |
| 2011-09-04 | Kevin Slowey | R | 27 | L 1-4 | @ ANA | 4 | 86 | L | 7.0 | 7 | 2 | 2 | 1 | 0 | 4 | 95 | 22 | 73 | 77% | 0-4 | 5.31 | 1.36 |
| 2011-09-05 | Anthony Swarzak | R | 26 | W 1-2 | vs CHA | 7 | 19 | L | 8.0 | 7 | 2 | 2 | 0 | 0 | 4 | 99 | 28 | 71 | 72% | 3-6 | 3.95 | 1.24 |
| 2011-09-05 | Scott Diamond | L | 25 | W 0-4 | vs CHA | 4 | 4 | L | 5.0 | 8 | 2 | 2 | 0 | 2 | 4 | 89 | 34 | 55 | 62% | 1-3 | 4.50 | 1.50 |
| 2011-09-06 | Liam Hendriks | R | 23 | W 0-3 | vs CHA | 1 | 1 | L | 7.0 | 4 | 3 | 3 | 1 | 3 | 4 | 99 | 34 | 65 | 66% | 0-1 | 3.86 | 1.00 |
| 2011-09-07 | Carl Pavano | R | 36 | L 5-4 | vs CHA | 29 | 269 | W | 5.1 | 10 | 3 | 1 | 0 | 1 | 1 | 99 | 34 | 65 | 66% | 8-11 | 4.52 | 1.39 |
| 2011-09-09 | Kevin Slowey | R | 27 | L 4-8 | @ DET | 5 | 87 | L | 4.0 | 7 | 6 | 6 | 2 | 0 | 2 | 59 | 18 | 41 | 69% | 0-5 | 6.07 | 1.40 |
| 2011-09-10 | Anthony Swarzak | R | 26 | L 2-3 | @ DET | 8 | 20 | - | 6.0 | 4 | 2 | 2 | 1 | 2 | 6 | 94 | 37 | 57 | 61% | 3-6 | 3.89 | 1.23 |
| 2011-09-11 | Scott Diamond | L | 25 | L 1-2 | @ DET | 5 | 5 | L | 6.0 | 7 | 2 | 1 | 0 | 4 | 4 | 96 | 36 | 60 | 63% | 1-4 | 3.90 | 1.57 |
| 2011-09-13 | Carl Pavano | R | 36 | L 0-4 | @ KCA | 30 | 270 | L | 7.0 | 11 | 4 | 3 | 2 | 1 | 5 | 107 | 43 | 64 | 60% | 8-12 | 4.50 | 1.40 |
| 2011-09-14 | Liam Hendriks | R | 23 | L 3-7 | @ KCA | 2 | 2 | L | 5.0 | 8 | 5 | 5 | 0 | 0 | 2 | 84 | 31 | 53 | 63% | 0-2 | 6.00 | 1.25 |
| 2011-09-16 | Kevin Slowey | R | 27 | W 6-7 | vs CLE | 6 | 88 | L | 4.0 | 7 | 5 | 5 | 1 | 0 | 2 | 84 | 30 | 54 | 64% | 0-6 | 6.51 | 1.43 |
| 2011-09-17 | Anthony Swarzak | R | 26 | W 4-10 | vs CLE | 9 | 21 | L | 1.2 | 7 | 7 | 7 | 1 | 1 | 0 | 54 | 24 | 30 | 56% | 3-7 | 4.50 | 1.29 |
| 2011-09-18 | Carl Pavano | R | 36 | W 5-6 | vs CLE | 31 | 271 | L | 6.2 | 5 | 4 | 1 | 1 | 1 | 6 | 105 | 35 | 70 | 67% | 8-13 | 4.39 | 1.38 |
| 2011-09-19 | Scott Diamond | L | 25 | L 4-6 | @ NYA | 6 | 6 | L | 4.0 | 10 | 5 | 5 | 1 | 3 | 1 | 91 | 40 | 51 | 56% | 1-5 | 4.76 | 1.76 |
| 2011-09-20 | Liam Hendriks | R | 23 | W 4-5 | vs SEA | 3 | 3 | - | 5.1 | 10 | 4 | 4 | 1 | 0 | 5 | 94 | 33 | 61 | 65% | 0-2 | 6.35 | 1.47 |
| 2011-09-21 | Kevin Slowey | R | 27 | W 4-5 | vs SEA | 7 | 89 | L | 6.2 | 6 | 5 | 5 | 0 | 0 | 6 | 87 | 22 | 65 | 75% | 0-7 | 6.50 | 1.35 |
| 2011-09-22 | Anthony Swarzak | R | 26 | L 3-2 | vs SEA | 10 | 22 | - | 6.0 | 9 | 2 | 2 | 0 | 2 | 4 | 97 | 36 | 61 | 63% | 3-7 | 4.41 | 1.32 |
| 2011-09-23 | Carl Pavano | R | 36 | L 5-6 | @ CLE | 32 | 272 | - | 6.1 | 10 | 5 | 5 | 1 | 1 | 3 | 103 | 38 | 65 | 63% | 8-13 | 4.48 | 1.39 |
| 2011-09-24 | Brian Duensing | L | 29 | L 2-8 | @ CLE | 28 | 50 | - | 5.0 | 3 | 2 | 2 | 0 | 1 | 4 | 80 | 30 | 50 | 63% | 9-14 | 5.22 | 1.51 |
| 2011-09-24 | Scott Diamond | L | 25 | L 6-7 | @ CLE | 7 | 7 | - | 5.1 | 6 | 4 | 4 | 0 | 2 | 1 | 89 | 28 | 61 | 69% | 1-5 | 5.08 | 1.74 |
| 2011-09-25 | Liam Hendriks | R | 23 | W 6-4 | @ CLE | 4 | 4 | - | 6.0 | 7 | 4 | 4 | 1 | 3 | 5 | 98 | 38 | 60 | 61% | 0-2 | 6.26 | 1.52 |
| 2011-09-26 | Kevin Slowey | R | 27 | W 3-7 | vs KCA | 8 | 90 | L | 5.2 | 10 | 5 | 5 | 1 | 0 | 3 | 95 | 32 | 63 | 66% | 0-8 | 6.71 | 1.41 |
| 2011-09-27 | Anthony Swarzak | R | 26 | L 7-4 | vs KCA | 11 | 23 | W | 6.1 | 10 | 2 | 2 | 0 | 0 | 6 | 97 | 29 | 68 | 70% | 4-7 | 4.32 | 1.34 |
| 2011-09-28 | Carl Pavano | R | 36 | L 1-0 | vs KCA | 33 | 273 | W | 9.0 | 5 | 0 | 0 | 0 | 0 | 3 | 91 | 26 | 65 | 71% | 9-13 | 4.30 | 1.36 |