| West | W | L | Pct | GB |
| SF Giants | 92 | 70 | .568 | -- |
| San Diego | 90 | 72 | .556 | 2.0 |
| Colorado | 83 | 79 | .512 | 9.0 |
| LA Dodgers | 80 | 82 | .494 | 12.0 |
| Arizona | 65 | 97 | .401 | 27.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2010-04-05 | Tim Lincecum | R | 26 | W 5-2 | @ HOU | 1 | 90 | W | 7.0 | 4 | 0 | 0 | 0 | 0 | 7 | 98 | 32 | 66 | 67% | 1-0 | 0.00 | 0.57 |
| 2010-04-06 | Barry Zito | L | 32 | W 3-0 | @ HOU | 1 | 321 | W | 6.0 | 3 | 0 | 0 | 0 | 1 | 5 | 90 | 28 | 62 | 69% | 1-0 | 0.00 | 0.67 |
| 2010-04-07 | Matt Cain | R | 26 | W 10-4 | @ HOU | 1 | 138 | - | 6.2 | 6 | 4 | 3 | 0 | 0 | 5 | 96 | 32 | 64 | 67% | 0-0 | 3.86 | 0.86 |
| 2010-04-09 | Jonathan Sanchez | L | 27 | L 5-4 | vs ATL | 1 | 67 | - | 4.1 | 7 | 3 | 3 | 0 | 2 | 6 | 86 | 34 | 52 | 60% | 0-0 | 6.75 | 2.25 |
| 2010-04-10 | Todd Wellemeyer | R | 32 | W 2-7 | vs ATL | 1 | 65 | L | 6.1 | 7 | 4 | 4 | 1 | 4 | 4 | 97 | 40 | 57 | 59% | 0-1 | 6.00 | 1.83 |
| 2010-04-11 | Tim Lincecum | R | 26 | L 6-3 | vs ATL | 2 | 91 | W | 7.0 | 5 | 2 | 2 | 1 | 1 | 10 | 108 | 32 | 76 | 70% | 2-0 | 1.29 | 0.71 |
| 2010-04-12 | Barry Zito | L | 32 | L 9-3 | vs PIT | 2 | 322 | W | 6.0 | 5 | 3 | 3 | 0 | 3 | 1 | 93 | 42 | 51 | 55% | 2-0 | 2.25 | 1.00 |
| 2010-04-13 | Matt Cain | R | 26 | W 5-6 | vs PIT | 2 | 139 | - | 6.0 | 5 | 3 | 3 | 1 | 2 | 3 | 86 | 37 | 49 | 57% | 0-0 | 4.15 | 1.00 |
| 2010-04-14 | Jonathan Sanchez | L | 27 | L 6-0 | vs PIT | 2 | 68 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 11 | 108 | 39 | 69 | 64% | 1-0 | 2.25 | 1.25 |
| 2010-04-16 | Todd Wellemeyer | R | 32 | L 8-10 | @ LAN | 2 | 66 | L | 4.0 | 6 | 7 | 7 | 3 | 3 | 4 | 82 | 31 | 51 | 62% | 0-2 | 9.90 | 2.00 |
| 2010-04-17 | Tim Lincecum | R | 26 | W 9-0 | @ LAN | 3 | 92 | W | 6.0 | 4 | 0 | 0 | 0 | 2 | 7 | 105 | 39 | 66 | 63% | 3-0 | 0.90 | 0.80 |
| 2010-04-18 | Barry Zito | L | 32 | L 1-2 | @ LAN | 3 | 323 | - | 7.1 | 4 | 1 | 1 | 0 | 1 | 3 | 102 | 35 | 67 | 66% | 2-0 | 1.89 | 0.89 |
| 2010-04-19 | Matt Cain | R | 26 | L 2-3 | @ SDN | 3 | 140 | - | 6.0 | 7 | 2 | 2 | 0 | 1 | 4 | 102 | 38 | 64 | 63% | 0-0 | 3.79 | 1.11 |
| 2010-04-20 | Jonathan Sanchez | L | 27 | L 0-1 | @ SDN | 3 | 69 | L | 7.0 | 1 | 1 | 1 | 0 | 3 | 10 | 110 | 44 | 66 | 60% | 1-1 | 1.89 | 1.00 |
| 2010-04-21 | Todd Wellemeyer | R | 32 | L 2-5 | @ SDN | 3 | 67 | L | 4.0 | 3 | 2 | 2 | 1 | 4 | 3 | 86 | 42 | 44 | 51% | 0-3 | 8.36 | 1.93 |
| 2010-04-23 | Tim Lincecum | R | 26 | L 4-1 | vs SLN | 4 | 93 | W | 7.0 | 6 | 1 | 1 | 0 | 3 | 8 | 120 | 49 | 71 | 59% | 4-0 | 1.00 | 0.93 |
| 2010-04-24 | Barry Zito | L | 32 | L 2-0 | vs SLN | 4 | 324 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 10 | 113 | 42 | 71 | 63% | 3-0 | 1.33 | 0.85 |
| 2010-04-25 | Matt Cain | R | 26 | W 0-2 | vs SLN | 4 | 141 | L | 5.0 | 6 | 2 | 2 | 1 | 1 | 4 | 97 | 30 | 67 | 69% | 0-1 | 3.75 | 1.17 |
| 2010-04-26 | Jonathan Sanchez | L | 27 | L 5-1 | vs PHI | 4 | 70 | W | 5.0 | 3 | 1 | 1 | 0 | 5 | 6 | 107 | 45 | 62 | 58% | 2-1 | 1.88 | 1.13 |
| 2010-04-27 | Todd Wellemeyer | R | 32 | L 6-2 | vs PHI | 4 | 68 | W | 7.0 | 3 | 2 | 2 | 0 | 3 | 4 | 99 | 37 | 62 | 63% | 1-3 | 6.43 | 1.57 |
| 2010-04-28 | Tim Lincecum | R | 26 | W 6-7 | vs PHI | 5 | 94 | - | 8.1 | 3 | 2 | 2 | 1 | 1 | 11 | 106 | 34 | 72 | 68% | 4-0 | 1.29 | 0.83 |
| 2010-04-30 | Barry Zito | L | 32 | L 5-2 | vs COL | 5 | 325 | W | 8.0 | 5 | 2 | 2 | 0 | 3 | 5 | 118 | 44 | 74 | 63% | 4-0 | 1.54 | 0.89 |
| 2010-05-01 | Matt Cain | R | 26 | L 6-1 | vs COL | 5 | 142 | W | 8.0 | 1 | 0 | 0 | 0 | 3 | 8 | 122 | 37 | 85 | 70% | 1-1 | 2.81 | 1.00 |
| 2010-05-02 | Jonathan Sanchez | L | 27 | W 1-4 | vs COL | 5 | 71 | L | 4.2 | 3 | 3 | 3 | 0 | 5 | 4 | 90 | 41 | 49 | 54% | 2-2 | 2.48 | 1.21 |
| 2010-05-04 | Tim Lincecum | R | 26 | W 9-6 | @ FLO | 6 | 95 | - | 7.0 | 5 | 3 | 3 | 1 | 1 | 13 | 109 | 39 | 70 | 64% | 4-0 | 1.71 | 0.83 |
| 2010-05-05 | Barry Zito | L | 32 | W 3-2 | @ FLO | 6 | 326 | W | 7.0 | 7 | 1 | 1 | 0 | 1 | 4 | 105 | 31 | 74 | 70% | 5-0 | 1.50 | 0.93 |
| 2010-05-06 | Matt Cain | R | 26 | W 6-3 | @ FLO | 6 | 143 | W | 7.0 | 4 | 2 | 2 | 0 | 3 | 6 | 106 | 36 | 70 | 66% | 2-1 | 2.77 | 1.00 |
| 2010-05-07 | Jonathan Sanchez | L | 27 | L 4-6 | @ NYN | 6 | 72 | - | 7.0 | 7 | 4 | 4 | 3 | 1 | 3 | 122 | 44 | 78 | 64% | 2-2 | 3.00 | 1.19 |
| 2010-05-08 | Todd Wellemeyer | R | 32 | L 4-5 | @ NYN | 5 | 69 | - | 4.1 | 3 | 4 | 4 | 0 | 5 | 4 | 95 | 43 | 52 | 55% | 1-3 | 5.90 | 1.52 |
| 2010-05-09 | Tim Lincecum | R | 26 | W 6-5 | @ NYN | 7 | 96 | - | 6.0 | 7 | 2 | 2 | 0 | 2 | 8 | 122 | 49 | 73 | 60% | 4-0 | 1.88 | 0.92 |
| 2010-05-11 | Barry Zito | L | 32 | W 2-3 | vs SDN | 7 | 327 | L | 5.0 | 6 | 3 | 3 | 0 | 7 | 2 | 108 | 47 | 61 | 56% | 5-1 | 1.91 | 1.11 |
| 2010-05-12 | Matt Cain | R | 26 | W 2-5 | vs SDN | 7 | 144 | L | 6.2 | 6 | 5 | 5 | 0 | 6 | 3 | 112 | 49 | 63 | 56% | 2-2 | 3.40 | 1.13 |
| 2010-05-13 | Jonathan Sanchez | L | 27 | W 0-1 | vs SDN | 7 | 73 | L | 8.0 | 3 | 1 | 1 | 0 | 1 | 5 | 105 | 39 | 66 | 63% | 2-3 | 2.66 | 1.07 |
| 2010-05-14 | Todd Wellemeyer | R | 32 | L 8-2 | vs HOU | 6 | 70 | W | 7.1 | 5 | 2 | 2 | 1 | 2 | 4 | 106 | 37 | 69 | 65% | 2-3 | 5.25 | 1.42 |
| 2010-05-15 | Tim Lincecum | R | 26 | L 2-1 | vs HOU | 8 | 97 | W | 8.0 | 4 | 1 | 1 | 0 | 5 | 5 | 120 | 53 | 67 | 56% | 5-0 | 1.77 | 0.95 |
| 2010-05-16 | Barry Zito | L | 32 | L 4-3 | vs HOU | 8 | 328 | W | 7.0 | 6 | 3 | 3 | 1 | 1 | 4 | 97 | 34 | 63 | 65% | 6-1 | 2.17 | 1.09 |
| 2010-05-17 | Matt Cain | R | 26 | L 1-3 | @ SDN | 8 | 145 | L | 6.0 | 6 | 2 | 2 | 1 | 5 | 5 | 121 | 50 | 71 | 59% | 2-3 | 3.35 | 1.22 |
| 2010-05-18 | Jonathan Sanchez | L | 27 | W 7-6 | @ SDN | 8 | 74 | - | 6.0 | 7 | 4 | 4 | 0 | 0 | 7 | 85 | 33 | 52 | 61% | 2-3 | 3.06 | 1.08 |
| 2010-05-19 | Todd Wellemeyer | R | 32 | L 1-13 | @ ARI | 7 | 71 | L | 5.0 | 4 | 5 | 5 | 3 | 5 | 3 | 101 | 44 | 57 | 56% | 2-4 | 5.71 | 1.46 |
| 2010-05-20 | Tim Lincecum | R | 26 | L 7-8 | @ ARI | 9 | 98 | - | 5.0 | 5 | 5 | 5 | 1 | 5 | 6 | 105 | 43 | 62 | 59% | 5-0 | 2.36 | 1.03 |
| 2010-05-21 | Barry Zito | L | 32 | L 1-6 | @ OAK | 9 | 329 | L | 6.2 | 9 | 6 | 6 | 0 | 1 | 3 | 103 | 42 | 61 | 59% | 6-2 | 2.80 | 1.13 |
| 2010-05-22 | Matt Cain | R | 26 | L 0-1 | @ OAK | 9 | 146 | L | 8.0 | 5 | 1 | 0 | 0 | 1 | 4 | 112 | 42 | 70 | 63% | 2-4 | 2.90 | 1.15 |
| 2010-05-23 | Jonathan Sanchez | L | 28 | L 0-3 | @ OAK | 9 | 75 | L | 7.0 | 3 | 2 | 2 | 0 | 5 | 4 | 110 | 44 | 66 | 60% | 2-4 | 3.00 | 1.09 |
| 2010-05-25 | Todd Wellemeyer | R | 32 | L 4-2 | vs WAS | 8 | 72 | W | 6.0 | 4 | 2 | 2 | 0 | 1 | 2 | 71 | 24 | 47 | 66% | 3-4 | 5.36 | 1.38 |
| 2010-05-26 | Tim Lincecum | R | 26 | W 3-7 | vs WAS | 10 | 99 | L | 4.2 | 6 | 6 | 6 | 0 | 5 | 5 | 95 | 40 | 55 | 58% | 5-1 | 3.00 | 1.12 |
| 2010-05-27 | Barry Zito | L | 32 | L 5-4 | vs WAS | 10 | 330 | - | 6.1 | 7 | 4 | 3 | 2 | 5 | 3 | 101 | 42 | 59 | 58% | 6-2 | 2.96 | 1.21 |
| 2010-05-28 | Matt Cain | R | 26 | L 5-0 | vs ARI | 10 | 147 | W | 9.0 | 1 | 0 | 0 | 0 | 0 | 9 | 121 | 39 | 82 | 68% | 3-4 | 2.51 | 1.01 |
| 2010-05-29 | Jonathan Sanchez | L | 28 | L 12-1 | vs ARI | 10 | 76 | W | 5.0 | 2 | 1 | 1 | 1 | 4 | 7 | 103 | 43 | 60 | 58% | 3-4 | 2.90 | 1.10 |
| 2010-05-30 | Todd Wellemeyer | R | 32 | L 6-5 | vs ARI | 9 | 73 | - | 6.2 | 6 | 2 | 2 | 1 | 3 | 7 | 88 | 32 | 56 | 64% | 3-4 | 5.00 | 1.37 |
| 2010-05-31 | Tim Lincecum | R | 26 | W 0-4 | vs COL | 11 | 100 | L | 5.2 | 6 | 4 | 3 | 0 | 5 | 3 | 121 | 48 | 73 | 60% | 5-2 | 3.13 | 1.18 |
| 2010-06-01 | Barry Zito | L | 32 | W 1-2 | vs COL | 11 | 331 | - | 7.0 | 4 | 1 | 1 | 0 | 3 | 8 | 103 | 39 | 64 | 62% | 6-2 | 2.80 | 1.19 |
| 2010-06-02 | Matt Cain | R | 26 | L 4-1 | vs COL | 11 | 148 | W | 8.0 | 4 | 1 | 1 | 1 | 3 | 5 | 114 | 45 | 69 | 61% | 4-4 | 2.37 | 1.00 |
| 2010-06-04 | Jonathan Sanchez | L | 28 | W 6-4 | @ PIT | 11 | 77 | W | 6.1 | 5 | 4 | 0 | 0 | 2 | 5 | 103 | 37 | 66 | 64% | 4-4 | 2.65 | 1.10 |
| 2010-06-05 | Todd Wellemeyer | R | 32 | L 3-6 | @ PIT | 10 | 74 | L | 3.0 | 9 | 6 | 6 | 2 | 3 | 2 | 72 | 30 | 42 | 58% | 3-5 | 5.68 | 1.51 |
| 2010-06-06 | Tim Lincecum | R | 26 | W 6-5 | @ PIT | 12 | 101 | - | 7.0 | 6 | 3 | 3 | 1 | 2 | 6 | 112 | 40 | 72 | 64% | 5-2 | 3.19 | 1.18 |
| 2010-06-07 | Barry Zito | L | 32 | W 6-5 | @ CIN | 12 | 332 | - | 5.2 | 8 | 5 | 5 | 1 | 3 | 4 | 96 | 33 | 63 | 66% | 6-2 | 3.15 | 1.24 |
| 2010-06-08 | Matt Cain | R | 26 | W 3-0 | @ CIN | 12 | 149 | W | 9.0 | 7 | 0 | 0 | 0 | 2 | 5 | 114 | 38 | 76 | 67% | 5-4 | 2.12 | 1.00 |
| 2010-06-09 | Jonathan Sanchez | L | 28 | L 3-6 | @ CIN | 12 | 78 | L | 5.0 | 7 | 3 | 3 | 0 | 2 | 4 | 93 | 39 | 54 | 58% | 4-5 | 2.84 | 1.15 |
| 2010-06-10 | Todd Wellemeyer | R | 32 | L 6-7 | @ CIN | 11 | 75 | - | 2.0 | 1 | 0 | 0 | 0 | 1 | 1 | 35 | 13 | 22 | 63% | 3-5 | 5.49 | 1.49 |
| 2010-06-11 | Tim Lincecum | R | 26 | L 6-2 | vs OAK | 13 | 102 | W | 8.0 | 7 | 2 | 2 | 0 | 1 | 7 | 105 | 33 | 72 | 69% | 6-2 | 3.10 | 1.16 |
| 2010-06-12 | Barry Zito | L | 32 | L 5-4 | vs OAK | 13 | 333 | W | 7.0 | 6 | 2 | 2 | 2 | 2 | 6 | 110 | 32 | 78 | 71% | 7-2 | 3.10 | 1.23 |
| 2010-06-13 | Matt Cain | R | 26 | L 6-2 | vs OAK | 13 | 150 | W | 7.0 | 8 | 1 | 1 | 0 | 1 | 4 | 115 | 40 | 75 | 65% | 6-4 | 2.05 | 1.02 |
| 2010-06-14 | Jonathan Sanchez | L | 28 | L 10-2 | vs BAL | 13 | 79 | W | 7.2 | 8 | 2 | 2 | 1 | 1 | 5 | 115 | 38 | 77 | 67% | 5-5 | 2.78 | 1.15 |
| 2010-06-15 | Joe Martinez | R | 27 | W 1-4 | vs BAL | 1 | 6 | L | 6.1 | 8 | 4 | 4 | 1 | 1 | 2 | 90 | 32 | 58 | 64% | 0-1 | 6.00 | 1.50 |
| 2010-06-16 | Tim Lincecum | R | 26 | L 6-3 | vs BAL | 14 | 103 | W | 6.0 | 8 | 2 | 2 | 0 | 4 | 10 | 111 | 37 | 74 | 67% | 7-2 | 3.10 | 1.22 |
| 2010-06-18 | Barry Zito | L | 32 | L 2-3 | @ TOR | 14 | 334 | L | 8.0 | 4 | 3 | 3 | 1 | 1 | 5 | 108 | 37 | 71 | 66% | 7-3 | 3.13 | 1.18 |
| 2010-06-19 | Matt Cain | R | 26 | L 0-3 | @ TOR | 14 | 151 | L | 7.2 | 6 | 3 | 3 | 1 | 2 | 3 | 112 | 40 | 72 | 64% | 6-5 | 2.16 | 1.02 |
| 2010-06-20 | Jonathan Sanchez | L | 28 | W 9-6 | @ TOR | 14 | 80 | - | 2.2 | 3 | 3 | 2 | 0 | 5 | 5 | 75 | 39 | 36 | 48% | 5-5 | 2.89 | 1.20 |
| 2010-06-22 | Tim Lincecum | R | 26 | W 3-1 | @ HOU | 15 | 104 | W | 8.0 | 7 | 1 | 0 | 0 | 2 | 7 | 125 | 43 | 82 | 66% | 8-2 | 2.85 | 1.21 |
| 2010-06-23 | Barry Zito | L | 32 | L 3-6 | @ HOU | 15 | 335 | L | 4.0 | 7 | 5 | 5 | 0 | 2 | 4 | 87 | 36 | 51 | 59% | 7-4 | 3.45 | 1.22 |
| 2010-06-24 | Matt Cain | R | 26 | L 5-7 | @ HOU | 15 | 152 | L | 2.2 | 9 | 7 | 7 | 2 | 2 | 2 | 72 | 25 | 47 | 65% | 6-6 | 2.71 | 1.10 |
| 2010-06-25 | Jonathan Sanchez | L | 28 | L 5-4 | vs BOS | 15 | 81 | W | 5.1 | 3 | 3 | 3 | 1 | 4 | 6 | 107 | 41 | 66 | 62% | 6-5 | 3.03 | 1.21 |
| 2010-06-26 | Madison Bumgarner | L | 21 | W 2-4 | vs BOS | 1 | 2 | L | 7.0 | 5 | 4 | 4 | 2 | 1 | 5 | 95 | 30 | 65 | 68% | 0-1 | 5.14 | 0.86 |
| 2010-06-27 | Tim Lincecum | R | 26 | W 1-5 | vs BOS | 16 | 105 | L | 3.0 | 5 | 4 | 4 | 1 | 3 | 4 | 79 | 35 | 44 | 56% | 8-3 | 3.12 | 1.25 |
| 2010-06-28 | Barry Zito | L | 32 | W 2-4 | vs LAN | 16 | 336 | - | 6.0 | 6 | 2 | 2 | 0 | 2 | 6 | 112 | 34 | 78 | 70% | 7-4 | 3.43 | 1.23 |
| 2010-06-29 | Matt Cain | R | 26 | W 2-4 | vs LAN | 16 | 153 | L | 5.0 | 7 | 4 | 4 | 0 | 3 | 6 | 104 | 36 | 68 | 65% | 6-7 | 2.92 | 1.14 |
| 2010-06-30 | Jonathan Sanchez | L | 28 | W 2-8 | vs LAN | 16 | 82 | L | 5.0 | 6 | 5 | 4 | 2 | 2 | 4 | 88 | 38 | 50 | 57% | 6-6 | 3.26 | 1.23 |
| 2010-07-01 | Madison Bumgarner | L | 21 | L 3-7 | @ COL | 2 | 3 | L | 7.0 | 9 | 4 | 3 | 1 | 1 | 5 | 113 | 41 | 72 | 64% | 0-2 | 4.50 | 1.14 |
| 2010-07-02 | Tim Lincecum | R | 26 | L 3-6 | @ COL | 17 | 106 | L | 6.0 | 9 | 4 | 4 | 1 | 4 | 4 | 102 | 41 | 61 | 60% | 8-4 | 3.27 | 1.30 |
| 2010-07-03 | Barry Zito | L | 32 | W 11-8 | @ COL | 17 | 337 | - | 5.1 | 8 | 6 | 6 | 1 | 1 | 1 | 88 | 27 | 61 | 69% | 7-4 | 3.76 | 1.25 |
| 2010-07-04 | Matt Cain | R | 26 | L 3-4 | @ COL | 17 | 154 | - | 7.0 | 6 | 3 | 3 | 1 | 4 | 6 | 119 | 44 | 75 | 63% | 6-7 | 2.97 | 1.16 |
| 2010-07-05 | Jonathan Sanchez | L | 28 | W 6-1 | @ MIL | 17 | 83 | W | 6.0 | 5 | 1 | 1 | 0 | 6 | 6 | 129 | 60 | 69 | 53% | 7-6 | 3.15 | 1.27 |
| 2010-07-06 | Madison Bumgarner | L | 21 | W 6-1 | @ MIL | 3 | 4 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 5 | 115 | 42 | 73 | 63% | 1-2 | 2.86 | 1.00 |
| 2010-07-07 | Tim Lincecum | R | 26 | W 15-2 | @ MIL | 18 | 107 | W | 7.0 | 4 | 1 | 1 | 1 | 2 | 10 | 97 | 39 | 58 | 60% | 9-4 | 3.15 | 1.27 |
| 2010-07-08 | Barry Zito | L | 32 | W 9-3 | @ MIL | 18 | 338 | - | 4.2 | 7 | 2 | 2 | 0 | 6 | 7 | 114 | 45 | 69 | 61% | 7-4 | 3.76 | 1.31 |
| 2010-07-09 | Matt Cain | R | 26 | L 1-8 | @ WAS | 18 | 155 | L | 6.2 | 11 | 8 | 7 | 2 | 3 | 6 | 117 | 46 | 71 | 61% | 6-8 | 3.35 | 1.21 |
| 2010-07-10 | Jonathan Sanchez | L | 28 | W 10-5 | @ WAS | 18 | 84 | - | 3.2 | 5 | 5 | 5 | 1 | 2 | 6 | 87 | 31 | 56 | 64% | 7-6 | 3.46 | 1.29 |
| 2010-07-11 | Madison Bumgarner | L | 21 | W 6-2 | @ WAS | 4 | 5 | W | 6.0 | 7 | 1 | 1 | 0 | 0 | 6 | 101 | 31 | 70 | 69% | 2-2 | 2.57 | 1.04 |
| 2010-07-15 | Tim Lincecum | R | 26 | L 2-0 | vs NYN | 19 | 108 | W | 9.0 | 6 | 0 | 0 | 0 | 1 | 5 | 109 | 33 | 76 | 70% | 10-4 | 2.93 | 1.24 |
| 2010-07-16 | Barry Zito | L | 32 | L 1-0 | vs NYN | 19 | 339 | W | 8.0 | 2 | 0 | 0 | 0 | 2 | 10 | 106 | 35 | 71 | 67% | 8-4 | 3.51 | 1.26 |
| 2010-07-17 | Matt Cain | R | 26 | L 8-4 | vs NYN | 19 | 156 | W | 7.0 | 4 | 2 | 2 | 1 | 1 | 3 | 93 | 30 | 63 | 68% | 7-8 | 3.30 | 1.19 |
| 2010-07-18 | Jonathan Sanchez | L | 28 | W 3-4 | vs NYN | 19 | 85 | - | 7.0 | 6 | 2 | 2 | 1 | 1 | 5 | 94 | 30 | 64 | 68% | 7-6 | 3.41 | 1.27 |
| 2010-07-19 | Madison Bumgarner | L | 21 | W 5-2 | @ LAN | 5 | 6 | W | 5.2 | 6 | 2 | 1 | 1 | 2 | 3 | 100 | 43 | 57 | 57% | 3-2 | 2.38 | 1.09 |
| 2010-07-20 | Tim Lincecum | R | 26 | W 7-5 | @ LAN | 20 | 109 | - | 4.2 | 7 | 5 | 5 | 1 | 3 | 2 | 82 | 39 | 43 | 52% | 10-4 | 3.18 | 1.28 |
| 2010-07-21 | Barry Zito | L | 32 | L 0-2 | @ LAN | 20 | 340 | L | 7.1 | 6 | 2 | 2 | 1 | 3 | 4 | 112 | 43 | 69 | 62% | 8-5 | 3.46 | 1.26 |
| 2010-07-22 | Matt Cain | R | 26 | W 3-0 | @ ARI | 20 | 157 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 9 | 120 | 42 | 78 | 65% | 8-8 | 3.11 | 1.16 |
| 2010-07-23 | Jonathan Sanchez | L | 28 | W 7-4 | @ ARI | 20 | 86 | - | 5.0 | 4 | 1 | 1 | 1 | 5 | 10 | 109 | 45 | 64 | 59% | 7-6 | 3.34 | 1.29 |
| 2010-07-24 | Madison Bumgarner | L | 21 | W 10-4 | @ ARI | 6 | 7 | W | 7.0 | 5 | 2 | 2 | 1 | 3 | 7 | 103 | 37 | 66 | 64% | 4-2 | 2.41 | 1.10 |
| 2010-07-25 | Tim Lincecum | R | 26 | W 3-2 | @ ARI | 21 | 110 | - | 8.0 | 9 | 2 | 2 | 0 | 1 | 5 | 113 | 35 | 78 | 69% | 10-4 | 3.13 | 1.28 |
| 2010-07-26 | Barry Zito | L | 32 | W 3-4 | vs FLO | 21 | 341 | L | 6.1 | 8 | 3 | 3 | 2 | 1 | 3 | 97 | 35 | 62 | 64% | 8-6 | 3.48 | 1.26 |
| 2010-07-27 | Matt Cain | R | 26 | L 6-4 | vs FLO | 21 | 158 | - | 7.0 | 4 | 3 | 3 | 2 | 3 | 6 | 98 | 40 | 58 | 59% | 8-8 | 3.15 | 1.15 |
| 2010-07-28 | Jonathan Sanchez | L | 28 | L 10-9 | vs FLO | 21 | 87 | - | 6.0 | 7 | 5 | 5 | 2 | 2 | 7 | 93 | 35 | 58 | 62% | 7-6 | 3.54 | 1.30 |
| 2010-07-29 | Madison Bumgarner | L | 21 | W 0-5 | vs FLO | 7 | 8 | L | 6.0 | 6 | 3 | 3 | 0 | 2 | 5 | 80 | 29 | 51 | 64% | 4-3 | 2.68 | 1.13 |
| 2010-07-30 | Tim Lincecum | R | 26 | L 6-5 | vs LAN | 22 | 111 | W | 7.0 | 7 | 2 | 2 | 1 | 2 | 9 | 122 | 42 | 80 | 66% | 11-4 | 3.10 | 1.28 |
| 2010-07-31 | Barry Zito | L | 32 | L 2-1 | vs LAN | 22 | 342 | - | 7.0 | 3 | 1 | 1 | 1 | 2 | 6 | 106 | 42 | 64 | 60% | 8-6 | 3.38 | 1.24 |
| 2010-08-01 | Matt Cain | R | 26 | L 2-0 | vs LAN | 22 | 159 | W | 7.2 | 4 | 0 | 0 | 0 | 1 | 7 | 121 | 46 | 75 | 62% | 9-8 | 2.98 | 1.13 |
| 2010-08-03 | Jonathan Sanchez | L | 28 | W 10-0 | @ COL | 22 | 88 | W | 6.0 | 3 | 0 | 0 | 0 | 4 | 9 | 96 | 41 | 55 | 57% | 8-6 | 3.38 | 1.30 |
| 2010-08-04 | Madison Bumgarner | L | 21 | L 1-6 | @ COL | 8 | 9 | L | 4.0 | 9 | 4 | 4 | 1 | 1 | 3 | 92 | 32 | 60 | 65% | 4-4 | 3.18 | 1.24 |
| 2010-08-05 | Tim Lincecum | R | 26 | L 2-3 | @ ATL | 23 | 112 | L | 6.1 | 6 | 3 | 3 | 2 | 3 | 7 | 103 | 36 | 67 | 65% | 11-5 | 3.14 | 1.28 |
| 2010-08-06 | Barry Zito | L | 32 | W 3-2 | @ ATL | 23 | 343 | - | 7.0 | 4 | 2 | 2 | 2 | 2 | 10 | 117 | 45 | 72 | 62% | 8-6 | 3.34 | 1.22 |
| 2010-08-07 | Matt Cain | R | 26 | L 0-3 | @ ATL | 23 | 160 | L | 5.0 | 6 | 3 | 3 | 0 | 2 | 4 | 90 | 37 | 53 | 59% | 9-9 | 3.06 | 1.14 |
| 2010-08-08 | Jonathan Sanchez | L | 28 | L 3-6 | @ ATL | 23 | 89 | L | 4.0 | 5 | 4 | 4 | 2 | 3 | 4 | 91 | 42 | 49 | 54% | 8-7 | 3.55 | 1.32 |
| 2010-08-09 | Madison Bumgarner | L | 21 | L 4-3 | vs CHN | 9 | 10 | - | 5.2 | 9 | 3 | 3 | 0 | 2 | 3 | 99 | 33 | 66 | 67% | 4-4 | 3.38 | 1.32 |
| 2010-08-10 | Tim Lincecum | R | 26 | W 6-8 | vs CHN | 24 | 113 | L | 4.0 | 8 | 6 | 6 | 1 | 1 | 4 | 88 | 34 | 54 | 61% | 11-6 | 3.40 | 1.30 |
| 2010-08-11 | Barry Zito | L | 32 | L 5-4 | vs CHN | 24 | 344 | - | 6.1 | 10 | 4 | 4 | 2 | 1 | 4 | 90 | 30 | 60 | 67% | 8-6 | 3.44 | 1.24 |
| 2010-08-12 | Matt Cain | R | 26 | L 8-7 | vs CHN | 24 | 161 | - | 6.0 | 8 | 3 | 3 | 0 | 1 | 9 | 120 | 39 | 81 | 68% | 9-9 | 3.11 | 1.15 |
| 2010-08-13 | Jonathan Sanchez | L | 28 | W 2-3 | vs SDN | 24 | 90 | L | 5.1 | 5 | 3 | 3 | 0 | 2 | 4 | 92 | 34 | 58 | 63% | 8-8 | 3.61 | 1.32 |
| 2010-08-14 | Madison Bumgarner | L | 21 | L 3-2 | vs SDN | 10 | 11 | - | 7.0 | 8 | 2 | 2 | 0 | 2 | 2 | 92 | 30 | 62 | 67% | 4-4 | 3.29 | 1.33 |
| 2010-08-15 | Tim Lincecum | R | 26 | W 2-8 | vs SDN | 25 | 114 | L | 3.2 | 8 | 6 | 5 | 0 | 3 | 6 | 93 | 36 | 57 | 61% | 11-7 | 3.62 | 1.35 |
| 2010-08-17 | Barry Zito | L | 32 | L 3-9 | @ PHI | 25 | 345 | L | 5.0 | 8 | 4 | 4 | 0 | 1 | 0 | 90 | 31 | 59 | 66% | 8-7 | 3.56 | 1.26 |
| 2010-08-18 | Matt Cain | R | 26 | L 2-8 | @ PHI | 25 | 162 | L | 6.0 | 7 | 5 | 2 | 1 | 1 | 4 | 101 | 35 | 66 | 65% | 9-10 | 3.11 | 1.16 |
| 2010-08-19 | Jonathan Sanchez | L | 28 | W 5-2 | @ PHI | 25 | 91 | W | 8.0 | 2 | 1 | 1 | 0 | 2 | 7 | 98 | 30 | 68 | 69% | 9-8 | 3.48 | 1.28 |
| 2010-08-20 | Madison Bumgarner | L | 21 | W 6-3 | @ SLN | 11 | 12 | W | 7.0 | 9 | 2 | 2 | 1 | 1 | 5 | 97 | 28 | 69 | 71% | 5-4 | 3.21 | 1.34 |
| 2010-08-21 | Tim Lincecum | R | 26 | L 1-5 | @ SLN | 26 | 115 | L | 5.1 | 6 | 4 | 4 | 1 | 2 | 4 | 95 | 30 | 65 | 68% | 11-8 | 3.71 | 1.35 |
| 2010-08-22 | Barry Zito | L | 32 | L 0-9 | @ SLN | 26 | 346 | L | 3.2 | 7 | 5 | 5 | 1 | 2 | 3 | 76 | 28 | 48 | 63% | 8-8 | 3.74 | 1.28 |
| 2010-08-23 | Matt Cain | R | 26 | L 11-2 | vs CIN | 26 | 163 | W | 8.0 | 5 | 2 | 2 | 0 | 1 | 7 | 123 | 45 | 78 | 63% | 10-10 | 3.07 | 1.14 |
| 2010-08-24 | Jonathan Sanchez | L | 28 | L 16-5 | vs CIN | 26 | 92 | - | 4.1 | 6 | 5 | 5 | 3 | 3 | 6 | 78 | 34 | 44 | 56% | 9-8 | 3.66 | 1.29 |
| 2010-08-25 | Madison Bumgarner | L | 21 | W 11-12 | vs CIN | 12 | 13 | - | 2.2 | 7 | 8 | 7 | 3 | 1 | 3 | 76 | 30 | 46 | 61% | 5-4 | 3.95 | 1.40 |
| 2010-08-27 | Tim Lincecum | R | 26 | W 0-6 | vs ARI | 27 | 116 | L | 6.0 | 5 | 4 | 4 | 1 | 4 | 6 | 105 | 40 | 65 | 62% | 11-9 | 3.79 | 1.35 |
| 2010-08-28 | Barry Zito | L | 32 | W 3-11 | vs ARI | 27 | 347 | L | 3.2 | 6 | 9 | 7 | 1 | 5 | 1 | 93 | 40 | 53 | 57% | 8-10 | 4.08 | 1.34 |
| 2010-08-29 | Matt Cain | R | 26 | L 9-7 | vs ARI | 27 | 164 | - | 6.1 | 6 | 3 | 3 | 1 | 1 | 7 | 108 | 39 | 69 | 64% | 10-10 | 3.12 | 1.14 |
| 2010-08-30 | Jonathan Sanchez | L | 28 | W 1-2 | vs COL | 27 | 93 | - | 8.0 | 5 | 1 | 1 | 0 | 2 | 6 | 107 | 39 | 68 | 64% | 9-8 | 3.53 | 1.27 |
| 2010-08-31 | Madison Bumgarner | L | 21 | L 5-2 | vs COL | 13 | 14 | - | 6.0 | 5 | 1 | 1 | 0 | 3 | 2 | 93 | 37 | 56 | 60% | 5-4 | 3.76 | 1.39 |
| 2010-09-01 | Tim Lincecum | R | 26 | L 2-1 | vs COL | 28 | 117 | W | 8.0 | 5 | 1 | 1 | 1 | 1 | 9 | 102 | 35 | 67 | 66% | 12-9 | 3.67 | 1.32 |
| 2010-09-03 | Barry Zito | L | 32 | L 2-4 | @ LAN | 28 | 348 | L | 4.0 | 4 | 4 | 4 | 1 | 4 | 5 | 72 | 29 | 43 | 60% | 8-11 | 4.19 | 1.36 |
| 2010-09-04 | Matt Cain | R | 26 | W 5-4 | @ LAN | 28 | 165 | - | 7.0 | 7 | 4 | 4 | 1 | 1 | 6 | 98 | 29 | 69 | 70% | 10-10 | 3.19 | 1.14 |
| 2010-09-05 | Jonathan Sanchez | L | 28 | W 3-0 | @ LAN | 28 | 94 | W | 7.0 | 3 | 0 | 0 | 0 | 1 | 9 | 111 | 37 | 74 | 67% | 10-8 | 3.38 | 1.24 |
| 2010-09-06 | Madison Bumgarner | L | 21 | W 2-0 | @ ARI | 14 | 15 | - | 7.1 | 5 | 0 | 0 | 0 | 1 | 7 | 97 | 35 | 62 | 64% | 5-4 | 3.45 | 1.35 |
| 2010-09-07 | Tim Lincecum | R | 26 | W 6-3 | @ ARI | 29 | 118 | W | 6.2 | 5 | 3 | 3 | 1 | 0 | 11 | 93 | 26 | 67 | 72% | 13-9 | 3.70 | 1.31 |
| 2010-09-08 | Barry Zito | L | 32 | L 1-3 | @ ARI | 29 | 349 | L | 6.0 | 4 | 2 | 2 | 0 | 3 | 7 | 92 | 40 | 52 | 57% | 8-12 | 4.15 | 1.35 |
| 2010-09-09 | Matt Cain | R | 26 | W 7-3 | @ SDN | 29 | 166 | W | 8.0 | 5 | 3 | 3 | 2 | 1 | 8 | 114 | 40 | 74 | 65% | 11-10 | 3.20 | 1.13 |
| 2010-09-10 | Jonathan Sanchez | L | 28 | W 1-0 | @ SDN | 29 | 95 | - | 5.0 | 1 | 0 | 0 | 0 | 7 | 4 | 88 | 44 | 44 | 50% | 10-8 | 3.28 | 1.25 |
| 2010-09-11 | Madison Bumgarner | L | 21 | L 0-1 | @ SDN | 15 | 16 | L | 7.0 | 3 | 1 | 1 | 1 | 0 | 4 | 79 | 24 | 55 | 70% | 5-5 | 3.29 | 1.28 |
| 2010-09-12 | Tim Lincecum | R | 26 | W 6-1 | @ SDN | 30 | 119 | W | 7.0 | 7 | 1 | 1 | 0 | 1 | 9 | 108 | 31 | 77 | 71% | 14-9 | 3.61 | 1.30 |
| 2010-09-14 | Barry Zito | L | 32 | W 0-1 | vs LAN | 30 | 350 | L | 5.2 | 1 | 1 | 0 | 0 | 3 | 5 | 82 | 33 | 49 | 60% | 8-13 | 4.02 | 1.33 |
| 2010-09-15 | Matt Cain | R | 26 | L 2-1 | vs LAN | 30 | 167 | W | 7.0 | 3 | 0 | 0 | 0 | 0 | 5 | 85 | 30 | 55 | 65% | 12-10 | 3.09 | 1.10 |
| 2010-09-16 | Jonathan Sanchez | L | 28 | L 10-2 | vs LAN | 30 | 96 | W | 7.0 | 4 | 2 | 1 | 1 | 0 | 12 | 87 | 23 | 64 | 74% | 11-8 | 3.20 | 1.23 |
| 2010-09-17 | Madison Bumgarner | L | 21 | W 0-3 | vs MIL | 16 | 17 | L | 5.2 | 9 | 2 | 2 | 0 | 1 | 5 | 97 | 26 | 71 | 73% | 5-6 | 3.27 | 1.30 |
| 2010-09-18 | Tim Lincecum | R | 26 | W 1-2 | vs MIL | 31 | 120 | L | 5.0 | 6 | 2 | 2 | 0 | 2 | 3 | 72 | 24 | 48 | 67% | 14-10 | 3.61 | 1.31 |
| 2010-09-19 | Barry Zito | L | 32 | L 9-2 | vs MIL | 31 | 351 | W | 6.0 | 3 | 2 | 2 | 1 | 1 | 3 | 85 | 28 | 57 | 67% | 9-13 | 3.98 | 1.31 |
| 2010-09-21 | Matt Cain | R | 26 | W 1-0 | @ CHN | 31 | 168 | - | 6.0 | 2 | 0 | 0 | 0 | 1 | 2 | 82 | 34 | 48 | 59% | 12-10 | 3.00 | 1.09 |
| 2010-09-22 | Jonathan Sanchez | L | 28 | L 0-2 | @ CHN | 31 | 97 | L | 5.2 | 4 | 2 | 1 | 1 | 2 | 6 | 104 | 39 | 65 | 63% | 11-9 | 3.16 | 1.23 |
| 2010-09-23 | Madison Bumgarner | L | 21 | W 13-0 | @ CHN | 17 | 18 | W | 7.0 | 7 | 0 | 0 | 0 | 1 | 9 | 109 | 33 | 76 | 70% | 6-6 | 3.06 | 1.29 |
| 2010-09-24 | Tim Lincecum | R | 26 | W 2-1 | @ COL | 32 | 121 | W | 8.0 | 2 | 1 | 1 | 0 | 0 | 9 | 106 | 32 | 74 | 70% | 15-10 | 3.51 | 1.27 |
| 2010-09-25 | Barry Zito | L | 32 | L 9-10 | @ COL | 32 | 352 | - | 4.1 | 5 | 4 | 4 | 0 | 3 | 4 | 81 | 31 | 50 | 62% | 9-13 | 4.09 | 1.32 |
| 2010-09-26 | Matt Cain | R | 26 | W 4-2 | @ COL | 32 | 169 | W | 9.0 | 3 | 2 | 2 | 1 | 1 | 8 | 113 | 33 | 80 | 71% | 13-10 | 2.96 | 1.06 |
| 2010-09-28 | Jonathan Sanchez | L | 28 | L 4-2 | vs ARI | 32 | 98 | W | 6.0 | 3 | 2 | 2 | 1 | 4 | 6 | 90 | 34 | 56 | 62% | 12-9 | 3.16 | 1.22 |
| 2010-09-29 | Tim Lincecum | R | 26 | L 3-1 | vs ARI | 33 | 122 | W | 7.0 | 6 | 1 | 1 | 1 | 4 | 11 | 114 | 42 | 72 | 63% | 16-10 | 3.44 | 1.27 |
| 2010-09-30 | Madison Bumgarner | L | 21 | L 4-1 | vs ARI | 18 | 19 | W | 5.0 | 7 | 1 | 1 | 0 | 1 | 7 | 85 | 33 | 52 | 61% | 7-6 | 3.00 | 1.31 |
| 2010-10-01 | Matt Cain | R | 26 | W 4-6 | vs SDN | 33 | 170 | L | 4.0 | 9 | 6 | 6 | 3 | 1 | 4 | 88 | 27 | 61 | 69% | 13-11 | 3.15 | 1.09 |
| 2010-10-02 | Barry Zito | L | 32 | W 2-4 | vs SDN | 33 | 353 | L | 3.0 | 5 | 4 | 3 | 0 | 4 | 4 | 65 | 27 | 38 | 58% | 9-14 | 4.16 | 1.35 |
| 2010-10-03 | Jonathan Sanchez | L | 28 | L 3-0 | vs SDN | 33 | 99 | W | 5.0 | 3 | 0 | 0 | 0 | 5 | 5 | 81 | 31 | 50 | 62% | 13-9 | 3.08 | 1.23 |