| John Bale | 42 | 0 | 0 | 0 | 42 | 28.3 | 7.2 | 10 | 5 | 43 | 20 | 90 | 48 | 53.3 | 115 | 136 | 9 | 1 | 1 | 2 | 4 | 0 | 0 | 23 | 46 | 47 | 0.98 | 5 | 538 | 333 | 205 | 95 | 111 | 34 | 7 | 17 | 2 |
| Brian Bannister | 26 | 26 | 11 | 154 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 601 | 668 | 28 | 0 | 4 | 4 | 15 | 0 | 1 | 89 | 266 | 250 | 1.06 | 12 | 2554 | 1572 | 982 | 430 | 451 | 175 | 21 | 77 | 10 |
| Bruce Chen | 17 | 9 | 3 | 48 | 8 | 14.3 | 6.8 | 0 | 0 | 3 | 0 | 6 | 0 | 0.0 | 246 | 279 | 12 | 2 | 4 | 3 | 4 | 4 | 4 | 81 | 66 | 139 | 0.47 | 4 | 1086 | 672 | 414 | 204 | 193 | 70 | 8 | 37 | 3 |
| Roman Colon | 43 | 0 | 0 | 0 | 43 | 50.3 | 7.0 | 6 | 2 | 39 | 11 | 81 | 26 | 32.1 | 195 | 220 | 5 | 3 | 2 | 1 | 7 | 1 | 1 | 26 | 71 | 96 | 0.74 | 4 | 801 | 470 | 331 | 95 | 133 | 75 | 3 | 26 | 5 |
| Juan Cruz | 46 | 0 | 0 | 0 | 46 | 50.3 | 7.5 | 8 | 2 | 26 | 5 | 54 | 11 | 20.4 | 187 | 219 | 11 | 1 | 1 | 1 | 2 | 1 | 0 | 34 | 40 | 111 | 0.36 | 3 | 962 | 579 | 383 | 175 | 164 | 89 | 3 | 35 | 4 |
| Kyle Davies | 22 | 22 | 9 | 123 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 461 | 538 | 15 | 2 | 4 | 1 | 17 | 4 | 2 | 68 | 167 | 215 | 0.78 | 13 | 2197 | 1262 | 935 | 352 | 336 | 192 | 20 | 66 | 13 |
| Lenny DiNardo | 5 | 5 | 0 | 21.3 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 99 | 117 | 4 | 2 | 1 | 0 | 1 | 0 | 0 | 7 | 55 | 38 | 1.45 | 4 | 455 | 278 | 177 | 74 | 81 | 30 | 0 | 8 | 3 |
| Kyle Farnsworth | 41 | 0 | 0 | 0 | 41 | 37.3 | 7.7 | 4 | 2 | 25 | 8 | 51 | 17 | 33.3 | 150 | 168 | 3 | 1 | 1 | 2 | 2 | 1 | 0 | 16 | 54 | 57 | 0.95 | 1 | 671 | 426 | 245 | 130 | 100 | 85 | 9 | 33 | 1 |
| Zack Greinke | 33 | 33 | 26 | 229.3 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 849 | 915 | 47 | 5 | 4 | 0 | 5 | 9 | 3 | 81 | 254 | 364 | 0.70 | 17 | 3472 | 2192 | 1280 | 577 | 650 | 347 | 48 | 194 | 1 |
| Luke Hochevar | 25 | 25 | 9 | 143 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 575 | 631 | 38 | 7 | 8 | 0 | 19 | 4 | 4 | 91 | 224 | 247 | 0.91 | 16 | 2359 | 1495 | 864 | 403 | 404 | 217 | 21 | 85 | 15 |
| Dusty Hughes | 8 | 1 | 0 | 4.3 | 7 | 9.7 | 5.6 | 2 | 0 | 7 | 1 | 12 | 2 | 16.7 | 53 | 62 | 1 | 0 | 2 | 0 | 0 | 1 | 0 | 9 | 18 | 20 | 0.90 | 2 | 232 | 137 | 95 | 33 | 39 | 27 | 2 | 13 | 2 |
| Anthony Lerew | 3 | 2 | 1 | 10.7 | 1 | 2.7 | 4.0 | 0 | 0 | 0 | 0 | 0 | 0 | -- | 53 | 62 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 9 | 13 | 34 | 0.38 | 2 | 257 | 153 | 104 | 48 | 42 | 16 | 1 | 6 | 3 |
| Ron Mahay | 41 | 0 | 0 | 0 | 41 | 41.3 | 6.8 | 4 | 0 | 37 | 17 | 78 | 41 | 52.6 | 176 | 200 | 10 | 2 | 2 | 1 | 0 | 0 | 0 | 10 | 59 | 86 | 0.69 | 4 | 752 | 448 | 304 | 115 | 106 | 82 | 12 | 22 | 7 |
| Victor Marte | 8 | 0 | 0 | 0 | 8 | 12 | 6.8 | 0 | 0 | 4 | 3 | 9 | 6 | 66.7 | 46 | 58 | 2 | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 19 | 20 | 0.95 | 1 | 205 | 104 | 101 | 18 | 35 | 12 | 2 | 5 | 2 |
| Gil Meche | 23 | 23 | 9 | 129 | 0 | 0 | -- | 0 | 0 | 0 | 0 | 0 | 0 | -- | 513 | 581 | 32 | 5 | 3 | 0 | 15 | 1 | 0 | 63 | 210 | 215 | 0.98 | 13 | 2284 | 1349 | 935 | 383 | 376 | 165 | 22 | 73 | 18 |
| Sidney Ponson | 14 | 9 | 4 | 50.3 | 5 | 8.3 | 5.0 | 0 | 1 | 7 | 2 | 15 | 4 | 26.7 | 238 | 273 | 13 | 4 | 2 | 1 | 1 | 0 | 1 | 20 | 110 | 104 | 1.06 | 6 | 978 | 580 | 398 | 137 | 185 | 44 | 11 | 21 | 9 |
| Horacio Ramirez | 19 | 1 | 0 | 4.3 | 18 | 18.3 | 6.4 | 3 | 0 | 14 | 3 | 27 | 8 | 29.6 | 92 | 104 | 8 | 1 | 0 | 3 | 1 | 0 | 0 | 10 | 35 | 45 | 0.78 | 3 | 375 | 219 | 156 | 55 | 66 | 18 | 5 | 8 | 0 |
| Carlos Rosa | 7 | 0 | 0 | 0 | 7 | 10.7 | 7.4 | 0 | 0 | 5 | 4 | 9 | 7 | 77.8 | 39 | 43 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 18 | 18 | 1.00 | 1 | 171 | 105 | 66 | 27 | 35 | 7 | 2 | 2 | 0 |
| Joakim Soria | 47 | 0 | 0 | 0 | 47 | 53 | 8.8 | 0 | 2 | 23 | 8 | 45 | 16 | 35.6 | 201 | 222 | 6 | 1 | 2 | 1 | 0 | 1 | 0 | 10 | 53 | 82 | 0.65 | 3 | 906 | 595 | 311 | 165 | 172 | 123 | 10 | 59 | 5 |
| Robinson Tejeda | 35 | 6 | 2 | 31.7 | 29 | 42 | 5.3 | 2 | 2 | 28 | 8 | 60 | 19 | 31.7 | 257 | 312 | 7 | 0 | 3 | 2 | 11 | 2 | 0 | 42 | 62 | 111 | 0.56 | 4 | 1379 | 830 | 549 | 269 | 214 | 174 | 15 | 72 | 7 |
| Doug Waechter | 5 | 0 | 0 | 0 | 5 | 5.3 | 8.4 | 0 | 0 | 0 | 0 | 0 | 0 | -- | 24 | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 12 | 0.83 | 0 | 114 | 71 | 43 | 23 | 20 | 6 | 1 | 2 | 0 |
| Jamey Wright | 65 | 0 | 0 | 0 | 65 | 79 | 7.1 | 11 | 3 | 47 | 17 | 108 | 41 | 38.0 | 295 | 351 | 9 | 1 | 7 | 5 | 7 | 2 | 3 | 59 | 144 | 96 | 1.50 | 11 | 1361 | 770 | 591 | 190 | 249 | 92 | 13 | 46 | 11 |
| Yasuhiko Yabuta | 12 | 0 | 0 | 0 | 12 | 14 | 6.1 | 1 | 0 | 6 | 1 | 12 | 3 | 25.0 | 69 | 78 | 8 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 18 | 43 | 0.42 | 1 | 337 | 195 | 142 | 49 | 61 | 24 | 2 | 7 | 2 |