| Central | W | L | Pct | GB |
| Chi Cubs | 97 | 64 | .602 | -- |
| Milwaukee | 90 | 72 | .556 | 7.5 |
| Houston | 86 | 75 | .534 | 11.0 |
| St. Louis | 86 | 76 | .531 | 11.5 |
| Cincinnati | 74 | 88 | .457 | 23.5 |
| Pittsburgh | 67 | 95 | .414 | 30.5 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2008-03-31 | Carlos Zambrano | R | 27 | W 3-4 | vs MIL | 1 | 181 | - | 6.2 | 3 | 0 | 0 | 0 | 1 | 5 | 85 | 30 | 55 | 65% | 0-0 | 0.00 | 0.57 |
| 2008-04-02 | Ted Lilly | L | 32 | W 2-8 | vs MIL | 1 | 195 | L | 4.2 | 5 | 4 | 4 | 1 | 0 | 4 | 77 | 20 | 57 | 74% | 0-1 | 7.20 | 1.00 |
| 2008-04-03 | Ryan Dempster | R | 31 | L 6-3 | vs MIL | 1 | 163 | W | 6.0 | 3 | 2 | 1 | 0 | 2 | 5 | 91 | 31 | 60 | 66% | 1-0 | 1.50 | 0.83 |
| 2008-04-04 | Rich Hill | L | 28 | W 3-4 | vs HOU | 1 | 53 | - | 6.0 | 4 | 2 | 2 | 1 | 3 | 4 | 87 | 35 | 52 | 60% | 0-0 | 3.00 | 1.17 |
| 2008-04-05 | Jason Marquis | R | 30 | L 9-7 | vs HOU | 1 | 171 | - | 5.1 | 8 | 5 | 4 | 1 | 1 | 2 | 81 | 31 | 50 | 62% | 0-0 | 7.20 | 1.80 |
| 2008-04-06 | Carlos Zambrano | R | 27 | L 3-2 | vs HOU | 2 | 182 | W | 7.0 | 7 | 2 | 2 | 1 | 0 | 7 | 101 | 32 | 69 | 68% | 1-0 | 1.29 | 0.79 |
| 2008-04-07 | Ted Lilly | L | 32 | W 10-8 | @ PIT | 2 | 196 | - | 3.2 | 7 | 5 | 5 | 0 | 2 | 1 | 80 | 30 | 50 | 63% | 0-1 | 10.13 | 1.75 |
| 2008-04-09 | Ryan Dempster | R | 31 | W 6-4 | @ PIT | 2 | 164 | - | 7.0 | 1 | 0 | 0 | 0 | 2 | 5 | 98 | 31 | 67 | 68% | 1-0 | 0.69 | 0.62 |
| 2008-04-10 | Rich Hill | L | 28 | W 7-3 | @ PIT | 2 | 54 | - | 3.0 | 3 | 3 | 3 | 0 | 4 | 3 | 73 | 39 | 34 | 47% | 0-0 | 5.00 | 1.56 |
| 2008-04-11 | Carlos Zambrano | R | 27 | L 3-5 | @ PHI | 3 | 183 | L | 6.0 | 9 | 5 | 5 | 1 | 1 | 6 | 104 | 44 | 60 | 58% | 1-1 | 3.15 | 1.05 |
| 2008-04-12 | Ted Lilly | L | 32 | L 1-7 | @ PHI | 3 | 197 | L | 4.1 | 7 | 5 | 5 | 2 | 2 | 3 | 91 | 33 | 58 | 64% | 0-2 | 9.69 | 1.77 |
| 2008-04-13 | Jason Marquis | R | 30 | W 6-5 | @ PHI | 2 | 172 | - | 5.0 | 4 | 2 | 2 | 1 | 5 | 2 | 95 | 46 | 49 | 52% | 0-0 | 5.40 | 1.80 |
| 2008-04-15 | Ryan Dempster | R | 31 | L 9-5 | vs CIN | 3 | 165 | W | 6.0 | 5 | 4 | 4 | 1 | 5 | 3 | 106 | 44 | 62 | 58% | 2-0 | 2.37 | 0.95 |
| 2008-04-16 | Carlos Zambrano | R | 27 | L 12-3 | vs CIN | 4 | 184 | W | 7.0 | 8 | 2 | 2 | 0 | 1 | 5 | 101 | 34 | 67 | 66% | 2-1 | 3.00 | 1.11 |
| 2008-04-17 | Ted Lilly | L | 32 | W 2-9 | vs CIN | 4 | 198 | L | 6.0 | 6 | 5 | 5 | 1 | 3 | 6 | 94 | 33 | 61 | 65% | 0-3 | 9.00 | 1.68 |
| 2008-04-18 | Rich Hill | L | 28 | L 3-2 | vs PIT | 3 | 55 | W | 5.0 | 3 | 1 | 1 | 0 | 3 | 4 | 82 | 36 | 46 | 56% | 1-0 | 3.86 | 1.43 |
| 2008-04-19 | Jason Marquis | R | 30 | L 13-1 | vs PIT | 3 | 173 | W | 6.0 | 6 | 1 | 1 | 0 | 1 | 7 | 101 | 35 | 66 | 65% | 1-0 | 3.94 | 1.56 |
| 2008-04-20 | Ryan Dempster | R | 31 | L 13-6 | vs PIT | 4 | 166 | W | 5.0 | 5 | 3 | 3 | 0 | 2 | 3 | 94 | 32 | 62 | 66% | 3-0 | 3.00 | 1.04 |
| 2008-04-21 | Carlos Zambrano | R | 27 | L 7-1 | vs NYN | 5 | 185 | W | 7.0 | 5 | 1 | 1 | 0 | 2 | 4 | 98 | 40 | 58 | 59% | 3-1 | 2.65 | 1.09 |
| 2008-04-22 | Ted Lilly | L | 32 | L 8-1 | vs NYN | 5 | 199 | W | 6.0 | 4 | 1 | 1 | 0 | 4 | 4 | 107 | 43 | 64 | 60% | 1-3 | 7.20 | 1.60 |
| 2008-04-23 | Rich Hill | L | 28 | W 7-6 | @ COL | 4 | 56 | - | 5.0 | 3 | 2 | 2 | 1 | 4 | 3 | 85 | 33 | 52 | 61% | 1-0 | 3.79 | 1.42 |
| 2008-04-24 | Jason Marquis | R | 30 | L 2-4 | @ COL | 4 | 174 | - | 7.0 | 8 | 2 | 2 | 1 | 2 | 4 | 100 | 35 | 65 | 65% | 1-0 | 3.52 | 1.52 |
| 2008-04-25 | Ryan Dempster | R | 31 | L 3-5 | @ WAS | 5 | 167 | - | 7.0 | 4 | 3 | 2 | 1 | 3 | 5 | 110 | 48 | 62 | 56% | 3-0 | 2.90 | 1.03 |
| 2008-04-26 | Carlos Zambrano | R | 27 | W 7-0 | @ WAS | 6 | 186 | W | 7.0 | 5 | 0 | 0 | 0 | 4 | 5 | 115 | 47 | 68 | 59% | 4-1 | 2.20 | 1.12 |
| 2008-04-27 | Ted Lilly | L | 32 | L 0-2 | @ WAS | 6 | 200 | L | 6.0 | 4 | 2 | 2 | 0 | 2 | 7 | 105 | 37 | 68 | 65% | 1-4 | 6.39 | 1.48 |
| 2008-04-29 | Jason Marquis | R | 30 | W 7-10 | vs MIL | 5 | 175 | L | 5.0 | 10 | 5 | 5 | 0 | 1 | 2 | 98 | 41 | 57 | 58% | 1-1 | 4.50 | 1.64 |
| 2008-04-30 | Ryan Dempster | R | 31 | L 19-5 | vs MIL | 6 | 168 | W | 6.0 | 4 | 3 | 3 | 0 | 5 | 1 | 105 | 42 | 63 | 60% | 4-0 | 3.16 | 1.11 |
| 2008-05-01 | Carlos Zambrano | R | 27 | W 3-4 | vs MIL | 7 | 187 | - | 6.1 | 7 | 1 | 1 | 1 | 2 | 3 | 111 | 40 | 71 | 64% | 4-1 | 2.11 | 1.17 |
| 2008-05-02 | Rich Hill | L | 28 | L 3-5 | @ SLN | 5 | 57 | - | 0.2 | 0 | 1 | 1 | 0 | 4 | 1 | 27 | 17 | 10 | 37% | 1-0 | 4.05 | 1.55 |
| 2008-05-03 | Ted Lilly | L | 32 | W 9-3 | @ SLN | 7 | 201 | W | 7.0 | 6 | 3 | 3 | 2 | 1 | 4 | 112 | 34 | 78 | 70% | 2-4 | 5.92 | 1.39 |
| 2008-05-04 | Jason Marquis | R | 30 | L 3-5 | @ SLN | 6 | 176 | L | 5.1 | 7 | 5 | 5 | 0 | 5 | 4 | 89 | 39 | 50 | 56% | 1-2 | 5.03 | 1.71 |
| 2008-05-05 | Ryan Dempster | R | 31 | L 3-5 | @ CIN | 7 | 169 | L | 6.0 | 4 | 5 | 0 | 1 | 1 | 7 | 82 | 27 | 55 | 67% | 4-1 | 2.72 | 1.07 |
| 2008-05-06 | Carlos Zambrano | R | 27 | W 3-0 | @ CIN | 8 | 188 | W | 8.0 | 3 | 0 | 0 | 0 | 3 | 3 | 116 | 46 | 70 | 60% | 5-1 | 1.80 | 1.11 |
| 2008-05-07 | Jon Lieber | R | 38 | L 0-9 | @ CIN | 1 | 327 | L | 2.0 | 7 | 5 | 5 | 4 | 0 | 2 | 47 | 12 | 35 | 74% | 2-2 | 3.86 | 1.43 |
| 2008-05-09 | Ted Lilly | L | 32 | L 3-1 | vs ARI | 8 | 202 | W | 7.0 | 3 | 1 | 1 | 1 | 2 | 10 | 102 | 37 | 65 | 64% | 3-4 | 5.20 | 1.29 |
| 2008-05-10 | Ryan Dempster | R | 31 | L 7-2 | vs ARI | 8 | 170 | - | 6.0 | 3 | 2 | 2 | 0 | 3 | 7 | 116 | 48 | 68 | 59% | 4-1 | 2.76 | 1.06 |
| 2008-05-11 | Sean Gallagher | R | 22 | L 6-4 | vs ARI | 1 | 1 | - | 4.1 | 5 | 4 | 4 | 0 | 3 | 6 | 82 | 31 | 51 | 62% | 0-0 | 6.75 | 1.75 |
| 2008-05-12 | Carlos Zambrano | R | 27 | L 12-3 | vs SDN | 9 | 189 | W | 7.0 | 6 | 3 | 3 | 1 | 2 | 5 | 95 | 36 | 59 | 62% | 6-1 | 2.03 | 1.11 |
| 2008-05-13 | Jason Marquis | R | 30 | W 3-4 | vs SDN | 7 | 177 | L | 5.2 | 9 | 4 | 4 | 1 | 1 | 3 | 76 | 27 | 49 | 64% | 1-3 | 5.31 | 1.74 |
| 2008-05-14 | Ted Lilly | L | 32 | L 8-5 | vs SDN | 9 | 203 | W | 6.0 | 6 | 4 | 4 | 0 | 1 | 11 | 101 | 33 | 68 | 67% | 4-4 | 5.29 | 1.27 |
| 2008-05-15 | Ryan Dempster | R | 31 | L 4-0 | vs SDN | 9 | 171 | W | 8.1 | 6 | 0 | 0 | 0 | 1 | 12 | 116 | 39 | 77 | 66% | 5-1 | 2.37 | 1.04 |
| 2008-05-16 | Sean Gallagher | R | 22 | L 7-4 | vs PIT | 2 | 2 | W | 6.0 | 4 | 1 | 1 | 0 | 3 | 3 | 91 | 31 | 60 | 66% | 1-0 | 4.50 | 1.50 |
| 2008-05-17 | Carlos Zambrano | R | 27 | W 6-7 | vs PIT | 10 | 190 | - | 4.0 | 7 | 5 | 4 | 0 | 3 | 3 | 72 | 33 | 39 | 54% | 6-1 | 2.45 | 1.20 |
| 2008-05-18 | Jason Marquis | R | 30 | L 4-3 | vs PIT | 8 | 178 | W | 6.0 | 4 | 3 | 2 | 1 | 1 | 3 | 94 | 33 | 61 | 65% | 2-3 | 5.00 | 1.62 |
| 2008-05-19 | Ted Lilly | L | 32 | W 7-2 | @ HOU | 10 | 204 | W | 5.1 | 4 | 2 | 2 | 0 | 2 | 6 | 94 | 35 | 59 | 63% | 5-4 | 5.14 | 1.27 |
| 2008-05-20 | Ryan Dempster | R | 31 | L 2-4 | @ HOU | 10 | 172 | L | 6.0 | 6 | 4 | 4 | 1 | 2 | 5 | 108 | 43 | 65 | 60% | 5-2 | 2.71 | 1.06 |
| 2008-05-21 | Sean Gallagher | R | 22 | L 3-5 | @ HOU | 3 | 3 | L | 4.2 | 8 | 5 | 5 | 1 | 1 | 4 | 99 | 33 | 66 | 67% | 1-1 | 5.68 | 1.58 |
| 2008-05-23 | Carlos Zambrano | R | 27 | W 12-3 | @ PIT | 11 | 191 | W | 7.0 | 6 | 2 | 2 | 0 | 1 | 6 | 109 | 34 | 75 | 69% | 7-1 | 2.47 | 1.18 |
| 2008-05-24 | Jason Marquis | R | 30 | L 4-5 | @ PIT | 9 | 179 | - | 5.1 | 7 | 3 | 3 | 1 | 3 | 2 | 87 | 33 | 54 | 62% | 2-3 | 4.94 | 1.63 |
| 2008-05-25 | Ted Lilly | L | 32 | L 5-6 | @ PIT | 11 | 205 | - | 6.0 | 10 | 4 | 4 | 3 | 2 | 2 | 101 | 33 | 68 | 67% | 5-4 | 5.23 | 1.34 |
| 2008-05-26 | Ryan Dempster | R | 31 | L 3-1 | vs LAN | 11 | 173 | W | 7.0 | 7 | 1 | 1 | 0 | 3 | 3 | 116 | 46 | 70 | 60% | 6-2 | 2.57 | 1.10 |
| 2008-05-27 | Sean Gallagher | R | 22 | L 3-1 | vs LAN | 4 | 4 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 3 | 110 | 38 | 72 | 65% | 2-1 | 4.50 | 1.38 |
| 2008-05-28 | Carlos Zambrano | R | 27 | L 2-1 | vs LAN | 12 | 192 | - | 8.0 | 6 | 1 | 1 | 0 | 4 | 3 | 129 | 51 | 78 | 60% | 7-1 | 2.33 | 1.19 |
| 2008-05-29 | Jason Marquis | R | 30 | L 8-4 | vs COL | 10 | 180 | - | 5.1 | 7 | 3 | 3 | 0 | 2 | 3 | 95 | 42 | 53 | 56% | 2-3 | 4.98 | 1.64 |
| 2008-05-30 | Ted Lilly | L | 32 | L 10-9 | vs COL | 12 | 206 | - | 3.0 | 8 | 7 | 4 | 2 | 0 | 3 | 61 | 16 | 45 | 74% | 5-4 | 5.54 | 1.40 |
| 2008-05-31 | Ryan Dempster | R | 31 | L 5-4 | vs COL | 12 | 174 | W | 5.0 | 3 | 3 | 3 | 2 | 4 | 7 | 92 | 39 | 53 | 58% | 7-2 | 2.76 | 1.12 |
| 2008-06-01 | Sean Gallagher | R | 22 | L 5-3 | vs COL | 5 | 5 | W | 5.2 | 6 | 3 | 3 | 0 | 0 | 8 | 108 | 37 | 71 | 66% | 3-1 | 4.50 | 1.31 |
| 2008-06-02 | Carlos Zambrano | R | 27 | W 7-6 | @ SDN | 13 | 193 | W | 5.0 | 5 | 3 | 3 | 0 | 4 | 2 | 92 | 44 | 48 | 52% | 8-1 | 2.51 | 1.22 |
| 2008-06-03 | Jason Marquis | R | 30 | W 9-6 | @ SDN | 11 | 181 | W | 5.0 | 4 | 3 | 3 | 0 | 5 | 2 | 112 | 54 | 58 | 52% | 3-3 | 5.02 | 1.66 |
| 2008-06-04 | Ted Lilly | L | 32 | L 1-2 | @ SDN | 13 | 207 | L | 7.1 | 7 | 2 | 2 | 1 | 2 | 8 | 107 | 37 | 70 | 65% | 5-5 | 5.25 | 1.39 |
| 2008-06-05 | Ryan Dempster | R | 31 | W 5-4 | @ LAN | 13 | 175 | - | 5.1 | 5 | 3 | 3 | 1 | 2 | 1 | 83 | 35 | 48 | 58% | 7-2 | 2.89 | 1.12 |
| 2008-06-06 | Sean Gallagher | R | 22 | L 0-3 | @ LAN | 6 | 6 | L | 5.0 | 3 | 2 | 2 | 0 | 3 | 6 | 88 | 38 | 50 | 57% | 3-2 | 4.38 | 1.30 |
| 2008-06-07 | Carlos Zambrano | R | 27 | L 3-7 | @ LAN | 14 | 194 | L | 6.2 | 13 | 7 | 7 | 2 | 1 | 6 | 114 | 38 | 76 | 67% | 8-2 | 3.00 | 1.28 |
| 2008-06-08 | Jason Marquis | R | 30 | W 3-1 | @ LAN | 12 | 182 | W | 6.1 | 3 | 1 | 0 | 0 | 1 | 2 | 88 | 36 | 52 | 59% | 4-3 | 4.57 | 1.57 |
| 2008-06-10 | Ted Lilly | L | 32 | L 10-5 | vs ATL | 14 | 208 | W | 6.2 | 4 | 3 | 3 | 1 | 3 | 8 | 98 | 37 | 61 | 62% | 6-5 | 5.13 | 1.35 |
| 2008-06-11 | Ryan Dempster | R | 31 | L 7-2 | vs ATL | 14 | 176 | W | 9.0 | 4 | 2 | 2 | 1 | 0 | 11 | 117 | 42 | 75 | 64% | 8-2 | 2.80 | 1.06 |
| 2008-06-12 | Carlos Zambrano | R | 27 | L 3-2 | vs ATL | 15 | 195 | - | 7.0 | 8 | 2 | 2 | 1 | 3 | 3 | 103 | 48 | 55 | 53% | 8-2 | 2.97 | 1.30 |
| 2008-06-13 | Sean Gallagher | R | 22 | L 2-3 | @ TOR | 7 | 7 | L | 5.0 | 7 | 3 | 3 | 2 | 2 | 5 | 96 | 39 | 57 | 59% | 3-3 | 4.50 | 1.36 |
| 2008-06-14 | Jason Marquis | R | 30 | W 6-2 | @ TOR | 13 | 183 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 1 | 78 | 29 | 49 | 63% | 5-3 | 4.26 | 1.50 |
| 2008-06-15 | Ted Lilly | L | 32 | W 7-4 | @ TOR | 15 | 209 | W | 6.0 | 1 | 0 | 0 | 0 | 5 | 6 | 110 | 42 | 68 | 62% | 7-5 | 4.76 | 1.33 |
| 2008-06-17 | Ryan Dempster | R | 31 | L 2-3 | @ TBA | 15 | 177 | - | 5.0 | 6 | 1 | 1 | 1 | 2 | 6 | 106 | 43 | 63 | 59% | 8-2 | 2.75 | 1.08 |
| 2008-06-18 | Carlos Zambrano | R | 27 | L 4-5 | @ TBA | 16 | 196 | L | 6.2 | 7 | 5 | 4 | 0 | 4 | 2 | 99 | 44 | 55 | 56% | 8-3 | 3.14 | 1.33 |
| 2008-06-19 | Sean Gallagher | R | 22 | L 3-8 | @ TBA | 8 | 8 | - | 6.0 | 4 | 1 | 0 | 0 | 2 | 3 | 112 | 48 | 64 | 57% | 3-3 | 3.94 | 1.31 |
| 2008-06-20 | Ted Lilly | L | 32 | L 4-3 | vs CHA | 16 | 210 | - | 6.2 | 7 | 3 | 3 | 2 | 3 | 8 | 105 | 32 | 73 | 70% | 7-5 | 4.70 | 1.34 |
| 2008-06-21 | Jason Marquis | R | 30 | L 11-7 | vs CHA | 14 | 184 | W | 7.0 | 8 | 5 | 5 | 2 | 1 | 4 | 93 | 26 | 67 | 72% | 6-3 | 4.44 | 1.48 |
| 2008-06-22 | Ryan Dempster | R | 31 | L 7-1 | vs CHA | 16 | 178 | W | 8.0 | 10 | 1 | 1 | 0 | 1 | 4 | 103 | 29 | 74 | 72% | 9-2 | 2.62 | 1.11 |
| 2008-06-24 | Sean Marshall | L | 26 | W 5-7 | vs BAL | 1 | 44 | L | 4.2 | 7 | 4 | 4 | 0 | 1 | 7 | 88 | 29 | 59 | 67% | 0-1 | 5.54 | 1.77 |
| 2008-06-25 | Ted Lilly | L | 32 | L 7-4 | vs BAL | 17 | 211 | W | 7.0 | 5 | 4 | 4 | 2 | 2 | 4 | 107 | 32 | 75 | 70% | 8-5 | 4.73 | 1.31 |
| 2008-06-26 | Jason Marquis | R | 30 | W 4-11 | vs BAL | 15 | 185 | L | 4.0 | 7 | 7 | 7 | 0 | 3 | 3 | 82 | 36 | 46 | 56% | 6-4 | 4.98 | 1.53 |
| 2008-06-27 | Ryan Dempster | R | 31 | L 3-10 | @ CHA | 17 | 179 | L | 2.1 | 7 | 8 | 8 | 1 | 3 | 1 | 74 | 33 | 41 | 55% | 9-3 | 3.26 | 1.18 |
| 2008-06-28 | Sean Gallagher | R | 22 | L 5-6 | @ CHA | 9 | 9 | - | 6.0 | 8 | 5 | 5 | 2 | 3 | 8 | 123 | 49 | 74 | 60% | 3-3 | 4.33 | 1.37 |
| 2008-06-29 | Sean Marshall | L | 26 | L 1-5 | @ CHA | 2 | 45 | L | 7.0 | 5 | 3 | 3 | 2 | 1 | 5 | 93 | 28 | 65 | 70% | 0-2 | 4.95 | 1.45 |
| 2008-06-30 | Ted Lilly | L | 32 | W 9-2 | @ SFN | 18 | 212 | W | 8.0 | 7 | 2 | 2 | 0 | 2 | 5 | 113 | 35 | 78 | 69% | 9-5 | 4.54 | 1.30 |
| 2008-07-01 | Jason Marquis | R | 30 | L 1-2 | @ SFN | 16 | 186 | L | 7.0 | 4 | 2 | 2 | 0 | 3 | 5 | 99 | 32 | 67 | 68% | 6-5 | 4.79 | 1.49 |
| 2008-07-02 | Ryan Dempster | R | 31 | W 6-5 | @ SFN | 18 | 180 | - | 6.0 | 5 | 2 | 2 | 1 | 2 | 7 | 91 | 35 | 56 | 62% | 9-3 | 3.24 | 1.18 |
| 2008-07-03 | Sean Gallagher | R | 23 | L 3-8 | @ SFN | 10 | 10 | L | 5.0 | 4 | 4 | 3 | 0 | 2 | 2 | 77 | 28 | 49 | 64% | 3-4 | 4.42 | 1.36 |
| 2008-07-04 | Carlos Zambrano | R | 27 | W 2-1 | @ SLN | 17 | 197 | W | 6.0 | 4 | 0 | 0 | 0 | 2 | 5 | 89 | 35 | 54 | 61% | 9-3 | 2.97 | 1.31 |
| 2008-07-05 | Ted Lilly | L | 33 | L 4-5 | @ SLN | 19 | 213 | - | 6.0 | 7 | 2 | 2 | 1 | 1 | 5 | 93 | 25 | 68 | 73% | 9-5 | 4.46 | 1.30 |
| 2008-07-06 | Sean Marshall | L | 26 | W 7-1 | @ SLN | 3 | 46 | W | 6.0 | 6 | 1 | 1 | 1 | 1 | 4 | 88 | 29 | 59 | 67% | 1-2 | 4.15 | 1.38 |
| 2008-07-08 | Ryan Dempster | R | 31 | L 7-3 | vs CIN | 19 | 181 | W | 7.0 | 2 | 1 | 1 | 0 | 4 | 5 | 102 | 44 | 58 | 57% | 10-3 | 3.13 | 1.16 |
| 2008-07-09 | Carlos Zambrano | R | 27 | L 5-1 | vs CIN | 18 | 198 | W | 8.0 | 1 | 1 | 1 | 1 | 0 | 5 | 102 | 37 | 65 | 64% | 10-3 | 2.85 | 1.23 |
| 2008-07-10 | Ted Lilly | L | 33 | W 7-12 | vs CIN | 20 | 214 | L | 2.2 | 6 | 4 | 4 | 2 | 2 | 3 | 62 | 25 | 37 | 60% | 9-6 | 4.70 | 1.35 |
| 2008-07-11 | Jason Marquis | R | 30 | L 3-1 | vs SFN | 17 | 187 | - | 7.0 | 3 | 0 | 0 | 0 | 2 | 4 | 81 | 26 | 55 | 68% | 6-5 | 4.45 | 1.43 |
| 2008-07-12 | Rich Harden | R | 27 | L 8-7 | vs SFN | 14 | 90 | - | 5.1 | 5 | 0 | 0 | 0 | 3 | 10 | 93 | 30 | 63 | 68% | 5-1 | 2.20 | 1.17 |
| 2008-07-13 | Ryan Dempster | R | 31 | W 2-4 | vs SFN | 20 | 182 | L | 6.2 | 7 | 4 | 4 | 0 | 3 | 6 | 117 | 49 | 68 | 58% | 10-4 | 3.24 | 1.18 |
| 2008-07-18 | Ted Lilly | L | 33 | L 1-2 | @ HOU | 21 | 215 | - | 7.0 | 6 | 1 | 1 | 1 | 2 | 6 | 107 | 41 | 66 | 62% | 9-6 | 4.50 | 1.34 |
| 2008-07-19 | Carlos Zambrano | R | 27 | L 1-4 | @ HOU | 19 | 199 | L | 6.1 | 6 | 4 | 4 | 0 | 6 | 3 | 106 | 44 | 62 | 58% | 10-4 | 2.98 | 1.26 |
| 2008-07-20 | Ryan Dempster | R | 31 | W 9-0 | @ HOU | 21 | 183 | W | 8.0 | 6 | 0 | 0 | 0 | 1 | 7 | 103 | 31 | 72 | 70% | 11-4 | 3.05 | 1.16 |
| 2008-07-21 | Rich Harden | R | 27 | L 0-2 | @ ARI | 15 | 91 | L | 7.0 | 1 | 1 | 1 | 1 | 2 | 10 | 115 | 46 | 69 | 60% | 5-2 | 2.12 | 1.11 |
| 2008-07-22 | Jason Marquis | R | 30 | L 2-9 | @ ARI | 18 | 188 | L | 6.0 | 5 | 3 | 3 | 1 | 2 | 3 | 97 | 38 | 59 | 61% | 6-6 | 4.46 | 1.42 |
| 2008-07-23 | Ted Lilly | L | 33 | W 10-6 | @ ARI | 22 | 216 | W | 6.0 | 6 | 3 | 3 | 1 | 3 | 6 | 121 | 51 | 70 | 58% | 10-6 | 4.50 | 1.34 |
| 2008-07-24 | Carlos Zambrano | R | 27 | L 6-3 | vs FLO | 20 | 200 | W | 7.0 | 6 | 2 | 2 | 1 | 0 | 6 | 125 | 44 | 81 | 65% | 11-4 | 2.96 | 1.24 |
| 2008-07-25 | Ryan Dempster | R | 31 | W 2-3 | vs FLO | 22 | 184 | - | 6.0 | 2 | 1 | 1 | 0 | 6 | 6 | 110 | 42 | 68 | 62% | 11-4 | 2.98 | 1.17 |
| 2008-07-26 | Rich Harden | R | 27 | W 2-3 | vs FLO | 16 | 92 | - | 5.0 | 2 | 1 | 1 | 1 | 3 | 10 | 87 | 34 | 53 | 61% | 5-2 | 2.11 | 1.11 |
| 2008-07-27 | Jason Marquis | R | 30 | L 9-6 | vs FLO | 19 | 189 | - | 6.0 | 9 | 6 | 6 | 3 | 3 | 6 | 102 | 39 | 63 | 62% | 6-6 | 4.70 | 1.45 |
| 2008-07-28 | Ted Lilly | L | 33 | W 6-4 | @ MIL | 23 | 217 | - | 6.0 | 7 | 3 | 3 | 2 | 1 | 4 | 93 | 32 | 61 | 66% | 10-6 | 4.50 | 1.34 |
| 2008-07-29 | Carlos Zambrano | R | 27 | W 7-1 | @ MIL | 21 | 201 | W | 8.0 | 5 | 0 | 0 | 0 | 2 | 9 | 117 | 42 | 75 | 64% | 12-4 | 2.79 | 1.22 |
| 2008-07-30 | Ryan Dempster | R | 31 | W 7-2 | @ MIL | 23 | 185 | W | 7.0 | 5 | 1 | 1 | 0 | 1 | 9 | 116 | 46 | 70 | 60% | 12-4 | 2.90 | 1.15 |
| 2008-07-31 | Rich Harden | R | 27 | W 11-4 | @ MIL | 17 | 93 | W | 7.0 | 6 | 1 | 1 | 1 | 0 | 9 | 104 | 34 | 70 | 67% | 6-2 | 2.05 | 1.09 |
| 2008-08-01 | Jason Marquis | R | 30 | W 0-3 | vs PIT | 20 | 190 | L | 6.0 | 8 | 3 | 3 | 1 | 1 | 2 | 99 | 39 | 60 | 61% | 6-7 | 4.69 | 1.45 |
| 2008-08-02 | Ted Lilly | L | 33 | L 5-1 | vs PIT | 24 | 218 | W | 6.1 | 6 | 1 | 1 | 0 | 3 | 5 | 108 | 40 | 68 | 63% | 11-6 | 4.34 | 1.34 |
| 2008-08-03 | Carlos Zambrano | R | 27 | L 8-5 | vs PIT | 22 | 202 | - | 5.0 | 3 | 2 | 1 | 1 | 1 | 2 | 82 | 35 | 47 | 57% | 12-4 | 2.76 | 1.20 |
| 2008-08-04 | Ryan Dempster | R | 31 | W 0-2 | vs HOU | 24 | 186 | L | 5.0 | 5 | 2 | 2 | 0 | 1 | 7 | 75 | 23 | 52 | 69% | 12-5 | 2.92 | 1.15 |
| 2008-08-05 | Rich Harden | R | 27 | L 11-7 | vs HOU | 18 | 94 | - | 5.2 | 8 | 5 | 4 | 2 | 1 | 8 | 89 | 26 | 63 | 71% | 6-2 | 2.27 | 1.11 |
| 2008-08-06 | Jason Marquis | R | 30 | L 11-4 | vs HOU | 21 | 191 | W | 6.1 | 6 | 4 | 4 | 1 | 2 | 3 | 106 | 36 | 70 | 66% | 7-7 | 4.72 | 1.44 |
| 2008-08-08 | Ted Lilly | L | 33 | L 3-2 | vs SLN | 25 | 219 | - | 7.1 | 7 | 2 | 2 | 1 | 2 | 4 | 82 | 25 | 57 | 70% | 11-6 | 4.26 | 1.34 |
| 2008-08-09 | Carlos Zambrano | R | 27 | W 3-12 | vs SLN | 23 | 203 | L | 4.1 | 10 | 9 | 9 | 4 | 1 | 3 | 87 | 31 | 56 | 64% | 12-5 | 3.22 | 1.25 |
| 2008-08-10 | Ryan Dempster | R | 31 | L 6-2 | vs SLN | 25 | 187 | W | 6.2 | 6 | 2 | 2 | 0 | 3 | 6 | 113 | 40 | 73 | 65% | 13-5 | 2.92 | 1.17 |
| 2008-08-13 | Jason Marquis | R | 30 | W 10-2 | @ ATL | 22 | 192 | W | 5.1 | 6 | 2 | 2 | 0 | 2 | 1 | 93 | 37 | 56 | 60% | 8-7 | 4.67 | 1.44 |
| 2008-08-13 | Rich Harden | R | 27 | W 8-0 | @ ATL | 19 | 95 | W | 5.0 | 2 | 0 | 0 | 0 | 5 | 2 | 88 | 41 | 47 | 53% | 7-2 | 2.17 | 1.13 |
| 2008-08-14 | Ted Lilly | L | 33 | W 11-7 | @ ATL | 26 | 220 | W | 6.0 | 8 | 4 | 4 | 1 | 2 | 8 | 92 | 29 | 63 | 68% | 12-6 | 4.32 | 1.35 |
| 2008-08-15 | Carlos Zambrano | R | 27 | W 6-5 | @ FLO | 24 | 204 | - | 6.0 | 4 | 5 | 5 | 1 | 5 | 6 | 120 | 58 | 62 | 52% | 12-5 | 3.38 | 1.25 |
| 2008-08-16 | Sean Marshall | L | 26 | L 1-2 | @ FLO | 4 | 47 | L | 5.0 | 4 | 2 | 2 | 1 | 3 | 8 | 78 | 30 | 48 | 62% | 2-3 | 3.56 | 1.16 |
| 2008-08-17 | Ryan Dempster | R | 31 | W 9-2 | @ FLO | 26 | 188 | W | 6.0 | 5 | 2 | 2 | 0 | 2 | 10 | 95 | 36 | 59 | 62% | 14-5 | 2.93 | 1.17 |
| 2008-08-19 | Rich Harden | R | 27 | L 5-0 | vs CIN | 20 | 96 | W | 7.0 | 2 | 0 | 0 | 0 | 0 | 10 | 94 | 32 | 62 | 66% | 8-2 | 2.04 | 1.08 |
| 2008-08-20 | Ted Lilly | L | 33 | W 1-2 | vs CIN | 27 | 221 | L | 7.0 | 2 | 2 | 2 | 0 | 2 | 7 | 100 | 30 | 70 | 70% | 12-7 | 4.25 | 1.32 |
| 2008-08-21 | Carlos Zambrano | R | 27 | L 3-2 | vs CIN | 25 | 205 | W | 7.0 | 6 | 1 | 1 | 1 | 4 | 4 | 105 | 46 | 59 | 56% | 13-5 | 3.29 | 1.26 |
| 2008-08-22 | Jason Marquis | R | 30 | W 5-13 | vs WAS | 23 | 193 | - | 5.1 | 4 | 4 | 4 | 0 | 3 | 3 | 87 | 31 | 56 | 64% | 8-7 | 4.77 | 1.44 |
| 2008-08-23 | Ryan Dempster | R | 31 | L 9-2 | vs WAS | 27 | 189 | W | 7.1 | 8 | 1 | 1 | 0 | 1 | 4 | 108 | 37 | 71 | 66% | 15-5 | 2.84 | 1.16 |
| 2008-08-24 | Rich Harden | R | 27 | L 6-1 | vs WAS | 21 | 97 | W | 7.0 | 2 | 1 | 1 | 1 | 0 | 11 | 108 | 32 | 76 | 70% | 9-2 | 2.00 | 1.03 |
| 2008-08-25 | Ted Lilly | L | 33 | W 12-3 | @ PIT | 28 | 222 | W | 7.0 | 7 | 3 | 3 | 2 | 1 | 7 | 110 | 34 | 76 | 69% | 13-7 | 4.23 | 1.31 |
| 2008-08-26 | Carlos Zambrano | R | 27 | W 14-9 | @ PIT | 26 | 206 | - | 4.1 | 8 | 6 | 6 | 0 | 4 | 3 | 107 | 46 | 61 | 57% | 13-5 | 3.54 | 1.30 |
| 2008-08-27 | Jason Marquis | R | 30 | W 2-0 | @ PIT | 24 | 194 | W | 7.0 | 5 | 0 | 0 | 0 | 0 | 3 | 94 | 34 | 60 | 64% | 9-7 | 4.53 | 1.40 |
| 2008-08-28 | Ryan Dempster | R | 31 | L 6-4 | vs PHI | 28 | 190 | - | 6.0 | 8 | 4 | 4 | 0 | 4 | 7 | 114 | 47 | 67 | 59% | 15-5 | 2.95 | 1.19 |
| 2008-08-29 | Rich Harden | R | 27 | L 3-2 | vs PHI | 22 | 98 | - | 5.0 | 3 | 2 | 1 | 0 | 4 | 5 | 99 | 40 | 59 | 60% | 9-2 | 1.99 | 1.05 |
| 2008-08-30 | Ted Lilly | L | 33 | W 2-5 | vs PHI | 29 | 223 | L | 6.2 | 6 | 3 | 3 | 1 | 0 | 5 | 108 | 35 | 73 | 68% | 13-8 | 4.22 | 1.29 |
| 2008-08-31 | Sean Marshall | L | 26 | W 3-5 | vs PHI | 5 | 48 | L | 5.1 | 9 | 5 | 5 | 1 | 2 | 2 | 90 | 33 | 57 | 63% | 3-4 | 4.06 | 1.25 |
| 2008-09-01 | Jason Marquis | R | 30 | W 0-3 | vs HOU | 25 | 195 | L | 6.0 | 5 | 2 | 2 | 0 | 3 | 8 | 111 | 44 | 67 | 60% | 9-8 | 4.47 | 1.40 |
| 2008-09-02 | Carlos Zambrano | R | 27 | W 7-9 | vs HOU | 27 | 207 | - | 5.0 | 5 | 3 | 3 | 0 | 3 | 3 | 86 | 31 | 55 | 64% | 13-5 | 3.59 | 1.31 |
| 2008-09-03 | Ryan Dempster | R | 31 | W 0-4 | vs HOU | 29 | 191 | L | 7.0 | 8 | 3 | 3 | 1 | 3 | 7 | 110 | 36 | 74 | 67% | 15-6 | 2.98 | 1.21 |
| 2008-09-05 | Ted Lilly | L | 33 | L 2-10 | @ CIN | 30 | 224 | L | 2.0 | 4 | 5 | 5 | 1 | 3 | 1 | 42 | 19 | 23 | 55% | 13-9 | 4.42 | 1.32 |
| 2008-09-06 | Jason Marquis | R | 30 | W 14-9 | @ CIN | 26 | 196 | W | 7.1 | 5 | 2 | 2 | 0 | 5 | 2 | 107 | 49 | 58 | 54% | 10-8 | 4.35 | 1.39 |
| 2008-09-07 | Sean Marshall | L | 26 | L 3-4 | @ CIN | 6 | 49 | - | 6.0 | 3 | 1 | 1 | 0 | 2 | 3 | 103 | 40 | 63 | 61% | 3-4 | 3.79 | 1.21 |
| 2008-09-09 | Ryan Dempster | R | 31 | L 3-4 | @ SLN | 30 | 192 | - | 7.0 | 7 | 3 | 3 | 1 | 2 | 6 | 103 | 36 | 67 | 65% | 15-6 | 3.02 | 1.21 |
| 2008-09-10 | Ted Lilly | L | 33 | W 4-3 | @ SLN | 31 | 225 | W | 8.0 | 5 | 1 | 1 | 0 | 0 | 5 | 93 | 29 | 64 | 69% | 14-9 | 4.28 | 1.29 |
| 2008-09-11 | Rich Harden | R | 27 | W 3-2 | @ SLN | 23 | 99 | W | 6.0 | 5 | 2 | 2 | 0 | 1 | 3 | 86 | 31 | 55 | 64% | 10-2 | 2.04 | 1.04 |
| 2008-09-14 | Carlos Zambrano | R | 27 | W 5-0 | @ HOU | 28 | 208 | W | 9.0 | 0 | 0 | 0 | 0 | 1 | 10 | 106 | 37 | 69 | 65% | 14-5 | 3.41 | 1.25 |
| 2008-09-15 | Ted Lilly | L | 33 | W 6-1 | @ HOU | 32 | 226 | W | 7.0 | 1 | 0 | 0 | 0 | 1 | 9 | 87 | 30 | 57 | 66% | 15-9 | 4.13 | 1.25 |
| 2008-09-16 | Ryan Dempster | R | 31 | L 5-4 | vs MIL | 31 | 193 | W | 6.0 | 7 | 2 | 2 | 1 | 1 | 9 | 113 | 35 | 78 | 69% | 16-6 | 3.02 | 1.21 |
| 2008-09-17 | Jason Marquis | R | 30 | W 2-6 | vs MIL | 27 | 197 | L | 5.1 | 6 | 3 | 3 | 0 | 5 | 3 | 99 | 37 | 62 | 63% | 10-9 | 4.39 | 1.42 |
| 2008-09-18 | Rich Harden | R | 27 | L 7-6 | vs MIL | 24 | 100 | - | 5.0 | 1 | 1 | 1 | 0 | 6 | 7 | 113 | 47 | 66 | 58% | 10-2 | 2.03 | 1.06 |
| 2008-09-19 | Carlos Zambrano | R | 27 | W 6-12 | vs SLN | 29 | 209 | L | 1.2 | 6 | 8 | 8 | 1 | 3 | 1 | 45 | 20 | 25 | 56% | 14-6 | 3.77 | 1.29 |
| 2008-09-20 | Ted Lilly | L | 33 | L 5-4 | vs SLN | 33 | 227 | W | 7.0 | 6 | 4 | 4 | 1 | 2 | 5 | 97 | 35 | 62 | 64% | 16-9 | 4.16 | 1.25 |
| 2008-09-21 | Ryan Dempster | R | 31 | L 5-1 | vs SLN | 32 | 194 | W | 5.0 | 6 | 1 | 1 | 0 | 0 | 1 | 67 | 20 | 47 | 70% | 17-6 | 2.99 | 1.21 |
| 2008-09-22 | Jason Marquis | R | 30 | W 9-5 | @ NYN | 28 | 198 | W | 6.2 | 8 | 4 | 4 | 1 | 4 | 4 | 112 | 50 | 62 | 55% | 11-9 | 4.42 | 1.43 |
| 2008-09-23 | Sean Marshall | L | 26 | L 2-6 | @ NYN | 7 | 50 | - | 5.0 | 4 | 2 | 2 | 0 | 2 | 7 | 70 | 25 | 45 | 64% | 3-4 | 3.60 | 1.22 |
| 2008-09-24 | Carlos Zambrano | R | 27 | W 9-6 | @ NYN | 30 | 210 | - | 4.2 | 3 | 5 | 5 | 1 | 4 | 2 | 86 | 37 | 49 | 57% | 14-6 | 3.90 | 1.29 |
| 2008-09-25 | Rich Harden | R | 27 | L 6-7 | @ NYN | 25 | 101 | - | 6.0 | 2 | 3 | 2 | 0 | 5 | 4 | 105 | 53 | 52 | 50% | 10-2 | 2.07 | 1.06 |
| 2008-09-26 | Ryan Dempster | R | 31 | L 1-5 | @ MIL | 33 | 195 | - | 5.0 | 4 | 1 | 1 | 0 | 1 | 4 | 80 | 31 | 49 | 61% | 17-6 | 2.96 | 1.21 |
| 2008-09-27 | Ted Lilly | L | 33 | W 7-3 | @ MIL | 34 | 228 | W | 6.0 | 2 | 1 | 1 | 0 | 1 | 4 | 80 | 27 | 53 | 66% | 17-9 | 4.08 | 1.22 |
| 2008-09-28 | Angel Guzman | R | 27 | L 1-3 | @ MIL | 1 | 14 | - | 2.0 | 1 | 0 | 0 | 0 | 0 | 4 | 33 | 9 | 24 | 73% | 0-0 | 5.40 | 1.40 |