| Central | W | L | Pct | GB |
| Chi White Sox | 99 | 63 | .611 | -- |
| Cleveland | 93 | 69 | .574 | 6.0 |
| Minnesota | 83 | 79 | .512 | 16.0 |
| Detroit | 71 | 91 | .438 | 28.0 |
| KC Royals | 56 | 106 | .346 | 43.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2005-04-04 | Jeremy Bonderman | R | 22 | L 11-2 | vs KCA | 1 | 61 | W | 7.0 | 6 | 1 | 1 | 0 | 2 | 7 | 100 | 29 | 71 | 71% | 1-0 | 1.29 | 1.14 |
| 2005-04-06 | Mike Maroth | L | 28 | W 2-7 | vs KCA | 1 | 88 | L | 3.2 | 11 | 5 | 5 | 0 | 0 | 2 | 85 | 36 | 49 | 58% | 0-1 | 11.25 | 2.75 |
| 2005-04-07 | Jason Johnson | R | 31 | L 7-3 | vs KCA | 1 | 167 | W | 6.2 | 5 | 0 | 0 | 0 | 1 | 4 | 76 | 23 | 53 | 70% | 1-0 | 0.00 | 0.86 |
| 2005-04-08 | Nate Robertson | R | 28 | W 3-4 | vs CLE | 1 | 42 | - | 7.0 | 5 | 2 | 1 | 0 | 2 | 4 | 90 | 36 | 54 | 60% | 0-0 | 1.29 | 1.00 |
| 2005-04-09 | Wil Ledezma | L | 24 | L 11-1 | vs CLE | 1 | 17 | W | 6.0 | 7 | 1 | 1 | 1 | 0 | 3 | 99 | 41 | 58 | 59% | 1-0 | 1.50 | 1.17 |
| 2005-04-10 | Jeremy Bonderman | R | 22 | W 6-7 | vs CLE | 2 | 62 | L | 6.0 | 7 | 7 | 7 | 0 | 3 | 4 | 104 | 38 | 66 | 63% | 1-1 | 5.54 | 1.38 |
| 2005-04-12 | Mike Maroth | L | 28 | L 4-5 | @ MIN | 2 | 89 | - | 5.0 | 5 | 3 | 2 | 2 | 1 | 3 | 82 | 30 | 52 | 63% | 0-1 | 7.00 | 1.89 |
| 2005-04-13 | Jason Johnson | R | 31 | L 4-8 | @ MIN | 2 | 168 | L | 0.1 | 7 | 5 | 5 | 1 | 1 | 0 | 35 | 13 | 22 | 63% | 1-1 | 6.43 | 2.00 |
| 2005-04-14 | Nate Robertson | R | 28 | L 4-10 | @ MIN | 2 | 43 | L | 5.0 | 5 | 6 | 4 | 0 | 5 | 0 | 100 | 47 | 53 | 53% | 0-1 | 3.75 | 1.42 |
| 2005-04-15 | Wil Ledezma | L | 24 | L 5-6 | @ KCA | 2 | 18 | - | 6.0 | 8 | 4 | 4 | 1 | 2 | 3 | 87 | 32 | 55 | 63% | 1-0 | 3.75 | 1.42 |
| 2005-04-16 | Jeremy Bonderman | R | 22 | W 7-1 | @ KCA | 3 | 63 | W | 8.0 | 6 | 1 | 1 | 1 | 0 | 5 | 102 | 30 | 72 | 71% | 2-1 | 3.86 | 1.14 |
| 2005-04-17 | Mike Maroth | L | 28 | W 6-1 | @ KCA | 3 | 90 | W | 7.2 | 5 | 1 | 1 | 1 | 1 | 3 | 103 | 38 | 65 | 63% | 1-1 | 4.50 | 1.44 |
| 2005-04-18 | Jason Johnson | R | 31 | W 13-3 | @ BAL | 3 | 169 | W | 7.0 | 7 | 2 | 2 | 1 | 0 | 0 | 83 | 25 | 58 | 70% | 2-1 | 4.50 | 1.50 |
| 2005-04-19 | Nate Robertson | R | 28 | L 4-8 | @ BAL | 3 | 44 | L | 3.1 | 7 | 6 | 6 | 2 | 1 | 4 | 73 | 25 | 48 | 66% | 0-2 | 6.60 | 1.67 |
| 2005-04-20 | Wil Ledezma | L | 24 | W 1-9 | vs CHA | 3 | 19 | L | 5.0 | 8 | 6 | 6 | 1 | 2 | 3 | 77 | 26 | 51 | 66% | 1-1 | 5.82 | 1.59 |
| 2005-04-21 | Jeremy Bonderman | R | 22 | W 3-4 | vs CHA | 4 | 64 | L | 6.1 | 7 | 4 | 4 | 0 | 2 | 4 | 100 | 35 | 65 | 65% | 2-2 | 4.33 | 1.22 |
| 2005-04-22 | Mike Maroth | L | 28 | L 5-4 | vs MIN | 4 | 91 | - | 6.0 | 5 | 2 | 2 | 0 | 1 | 3 | 74 | 26 | 48 | 65% | 1-1 | 4.09 | 1.32 |
| 2005-04-25 | Jason Johnson | R | 31 | L 6-4 | vs MIN | 4 | 170 | - | 6.2 | 5 | 3 | 3 | 0 | 4 | 3 | 108 | 48 | 60 | 56% | 2-1 | 4.29 | 1.43 |
| 2005-04-27 | Jeremy Bonderman | R | 22 | W 10-3 | @ CLE | 5 | 65 | W | 8.0 | 3 | 2 | 2 | 2 | 1 | 7 | 89 | 28 | 61 | 69% | 3-2 | 3.86 | 1.06 |
| 2005-04-28 | Mike Maroth | L | 28 | W 3-2 | @ CLE | 5 | 92 | W | 6.0 | 4 | 2 | 2 | 2 | 1 | 8 | 97 | 36 | 61 | 63% | 2-1 | 3.86 | 1.21 |
| 2005-04-29 | Nate Robertson | R | 28 | W 3-2 | @ CHA | 4 | 45 | - | 6.0 | 4 | 1 | 0 | 0 | 7 | 1 | 99 | 46 | 53 | 54% | 0-2 | 4.71 | 1.71 |
| 2005-04-30 | Jason Johnson | R | 32 | L 3-4 | @ CHA | 5 | 171 | L | 6.2 | 6 | 4 | 4 | 0 | 3 | 1 | 107 | 45 | 62 | 58% | 2-2 | 4.67 | 1.44 |
| 2005-05-01 | Wil Ledezma | L | 24 | L 0-8 | @ CHA | 4 | 20 | L | 5.0 | 6 | 6 | 5 | 0 | 4 | 1 | 107 | 46 | 61 | 57% | 1-2 | 6.55 | 1.68 |
| 2005-05-02 | Jeremy Bonderman | R | 23 | L 8-3 | vs BOS | 6 | 66 | W | 6.0 | 8 | 3 | 3 | 0 | 5 | 6 | 112 | 46 | 66 | 59% | 4-2 | 3.95 | 1.22 |
| 2005-05-03 | Mike Maroth | L | 28 | W 3-5 | vs BOS | 6 | 93 | L | 6.0 | 5 | 5 | 5 | 1 | 6 | 6 | 109 | 48 | 61 | 56% | 2-2 | 4.50 | 1.32 |
| 2005-05-04 | Nate Robertson | R | 28 | W 3-4 | vs BOS | 5 | 46 | - | 6.2 | 9 | 3 | 2 | 0 | 3 | 3 | 96 | 36 | 60 | 63% | 0-2 | 4.18 | 1.71 |
| 2005-05-05 | Jason Johnson | R | 32 | W 1-2 | vs BOS | 6 | 172 | - | 7.0 | 8 | 1 | 1 | 0 | 2 | 4 | 105 | 39 | 66 | 63% | 2-2 | 3.97 | 1.44 |
| 2005-05-06 | Wil Ledezma | L | 24 | L 3-4 | @ ANA | 5 | 21 | L | 5.1 | 7 | 4 | 4 | 0 | 3 | 3 | 119 | 43 | 76 | 64% | 1-3 | 6.67 | 1.74 |
| 2005-05-07 | Jeremy Bonderman | R | 23 | W 2-1 | @ ANA | 7 | 67 | W | 8.0 | 4 | 1 | 1 | 1 | 0 | 8 | 110 | 33 | 77 | 70% | 5-2 | 3.49 | 1.10 |
| 2005-05-08 | Mike Maroth | L | 28 | W 10-1 | @ ANA | 7 | 94 | W | 8.0 | 3 | 1 | 1 | 1 | 2 | 2 | 98 | 39 | 59 | 60% | 3-2 | 3.86 | 1.19 |
| 2005-05-09 | Nate Robertson | R | 28 | W 2-0 | @ TEX | 6 | 47 | W | 8.0 | 6 | 0 | 0 | 0 | 1 | 3 | 104 | 37 | 67 | 64% | 1-2 | 3.25 | 1.53 |
| 2005-05-10 | Jason Johnson | R | 32 | L 4-5 | @ TEX | 7 | 173 | L | 8.0 | 8 | 5 | 5 | 2 | 0 | 6 | 90 | 27 | 63 | 70% | 2-3 | 4.29 | 1.36 |
| 2005-05-11 | Wil Ledezma | L | 24 | W 6-5 | @ TEX | 6 | 22 | - | 5.0 | 3 | 3 | 0 | 0 | 3 | 4 | 100 | 44 | 56 | 56% | 1-3 | 5.63 | 1.66 |
| 2005-05-14 | Jeremy Bonderman | R | 23 | W 2-4 | vs ANA | 8 | 68 | - | 6.0 | 6 | 2 | 2 | 0 | 1 | 7 | 76 | 24 | 52 | 68% | 5-2 | 3.44 | 1.11 |
| 2005-05-14 | Mike Maroth | L | 28 | L 3-2 | vs ANA | 8 | 95 | W | 6.1 | 7 | 2 | 2 | 0 | 0 | 6 | 95 | 31 | 64 | 67% | 4-2 | 3.67 | 1.16 |
| 2005-05-15 | Nate Robertson | R | 28 | W 3-9 | vs ANA | 7 | 48 | L | 3.0 | 5 | 6 | 1 | 0 | 2 | 2 | 72 | 30 | 42 | 58% | 1-3 | 3.23 | 1.59 |
| 2005-05-17 | Jason Johnson | R | 32 | L 4-3 | vs TBA | 8 | 174 | - | 8.0 | 7 | 3 | 2 | 1 | 2 | 3 | 95 | 32 | 63 | 66% | 2-3 | 3.96 | 1.32 |
| 2005-05-18 | Wil Ledezma | L | 24 | L 6-4 | vs TBA | 7 | 23 | W | 5.0 | 5 | 4 | 4 | 2 | 2 | 7 | 98 | 36 | 62 | 63% | 2-3 | 5.84 | 1.62 |
| 2005-05-19 | Mike Maroth | L | 28 | W 2-6 | vs TBA | 9 | 96 | L | 6.0 | 9 | 6 | 6 | 2 | 2 | 3 | 99 | 35 | 64 | 65% | 4-3 | 4.25 | 1.24 |
| 2005-05-20 | Jeremy Bonderman | R | 23 | W 2-6 | vs ARI | 9 | 69 | - | 6.0 | 7 | 2 | 2 | 0 | 4 | 4 | 106 | 40 | 66 | 62% | 5-2 | 3.39 | 1.18 |
| 2005-05-21 | Nate Robertson | R | 28 | L 3-2 | vs ARI | 8 | 49 | - | 6.2 | 4 | 1 | 1 | 0 | 4 | 5 | 100 | 41 | 59 | 59% | 1-3 | 2.93 | 1.52 |
| 2005-05-22 | Jason Johnson | R | 32 | W 0-1 | vs ARI | 9 | 175 | L | 8.0 | 5 | 1 | 1 | 0 | 3 | 6 | 107 | 39 | 68 | 64% | 2-4 | 3.57 | 1.28 |
| 2005-05-24 | Wil Ledezma | L | 24 | L 3-12 | @ NYA | 8 | 24 | L | 4.0 | 7 | 7 | 6 | 4 | 0 | 1 | 70 | 24 | 46 | 66% | 2-4 | 6.59 | 1.63 |
| 2005-05-25 | Mike Maroth | L | 28 | L 2-4 | @ NYA | 10 | 97 | L | 5.0 | 8 | 4 | 4 | 0 | 3 | 2 | 78 | 35 | 43 | 55% | 4-4 | 4.50 | 1.32 |
| 2005-05-26 | Jeremy Bonderman | R | 23 | L 3-4 | @ NYA | 10 | 70 | L | 6.0 | 9 | 4 | 3 | 1 | 2 | 4 | 116 | 39 | 77 | 66% | 5-3 | 3.49 | 1.24 |
| 2005-05-27 | Nate Robertson | R | 28 | W 4-3 | @ BAL | 9 | 50 | W | 7.2 | 6 | 3 | 3 | 0 | 1 | 1 | 93 | 28 | 65 | 70% | 2-3 | 3.06 | 1.45 |
| 2005-05-28 | Jason Johnson | R | 32 | W 5-3 | @ BAL | 10 | 176 | W | 8.0 | 7 | 3 | 3 | 2 | 1 | 3 | 105 | 39 | 66 | 63% | 3-4 | 3.55 | 1.24 |
| 2005-05-29 | Wil Ledezma | L | 24 | W 8-6 | @ BAL | 9 | 25 | - | 4.0 | 3 | 4 | 4 | 0 | 5 | 3 | 89 | 40 | 49 | 55% | 2-4 | 6.80 | 1.67 |
| 2005-05-31 | Mike Maroth | L | 28 | W 2-8 | vs TEX | 11 | 98 | L | 4.2 | 9 | 6 | 6 | 1 | 1 | 5 | 102 | 32 | 70 | 69% | 4-5 | 5.06 | 1.39 |
| 2005-06-01 | Jeremy Bonderman | R | 23 | L 6-4 | vs TEX | 11 | 71 | W | 7.1 | 10 | 4 | 4 | 2 | 0 | 6 | 99 | 30 | 69 | 70% | 6-3 | 3.60 | 1.24 |
| 2005-06-02 | Nate Robertson | R | 28 | L 6-5 | vs TEX | 10 | 51 | - | 6.1 | 7 | 4 | 3 | 0 | 2 | 4 | 106 | 36 | 70 | 66% | 2-3 | 3.15 | 1.43 |
| 2005-06-03 | Jason Johnson | R | 32 | L 5-3 | vs BAL | 11 | 177 | W | 8.0 | 6 | 3 | 1 | 0 | 1 | 6 | 100 | 32 | 68 | 68% | 4-4 | 3.28 | 1.20 |
| 2005-06-04 | Wil Ledezma | L | 24 | W 7-14 | vs BAL | 10 | 26 | - | 4.1 | 7 | 7 | 5 | 1 | 3 | 2 | 96 | 33 | 63 | 66% | 2-4 | 7.02 | 1.70 |
| 2005-06-05 | Mike Maroth | L | 28 | W 2-6 | vs BAL | 12 | 99 | L | 8.0 | 10 | 6 | 2 | 0 | 1 | 1 | 101 | 31 | 70 | 69% | 4-6 | 4.75 | 1.39 |
| 2005-06-06 | Jeremy Bonderman | R | 23 | L 3-5 | @ LAN | 12 | 72 | L | 6.0 | 5 | 5 | 5 | 2 | 2 | 5 | 87 | 35 | 52 | 60% | 6-4 | 3.89 | 1.23 |
| 2005-06-07 | Nate Robertson | R | 28 | W 8-4 | @ LAN | 11 | 52 | - | 5.0 | 5 | 4 | 4 | 1 | 4 | 3 | 88 | 34 | 54 | 61% | 2-3 | 3.46 | 1.46 |
| 2005-06-08 | Jason Johnson | R | 32 | L 1-3 | @ LAN | 12 | 178 | L | 6.2 | 8 | 3 | 3 | 1 | 1 | 3 | 93 | 30 | 63 | 68% | 4-5 | 3.33 | 1.21 |
| 2005-06-10 | Mike Maroth | L | 28 | L 0-2 | @ COL | 13 | 100 | L | 7.0 | 7 | 2 | 2 | 1 | 2 | 3 | 101 | 33 | 68 | 67% | 4-7 | 4.56 | 1.38 |
| 2005-06-11 | Jeremy Bonderman | R | 23 | W 6-4 | @ COL | 13 | 73 | W | 6.0 | 8 | 4 | 4 | 0 | 2 | 2 | 94 | 35 | 59 | 63% | 7-4 | 4.03 | 1.26 |
| 2005-06-12 | Nate Robertson | R | 28 | L 3-7 | @ COL | 12 | 53 | L | 5.1 | 8 | 6 | 6 | 2 | 1 | 5 | 87 | 34 | 53 | 61% | 2-4 | 3.99 | 1.49 |
| 2005-06-14 | Jason Johnson | R | 32 | L 8-4 | vs SDN | 13 | 179 | - | 2.0 | 1 | 0 | 0 | 0 | 1 | 1 | 30 | 11 | 19 | 63% | 4-5 | 3.25 | 1.20 |
| 2005-06-15 | Mike Maroth | L | 28 | L 8-2 | vs SDN | 14 | 101 | W | 8.0 | 6 | 1 | 1 | 0 | 0 | 5 | 100 | 37 | 63 | 63% | 5-7 | 4.24 | 1.32 |
| 2005-06-16 | Jeremy Bonderman | R | 23 | L 3-1 | vs SDN | 14 | 74 | W | 7.0 | 4 | 1 | 1 | 1 | 3 | 4 | 103 | 45 | 58 | 56% | 8-4 | 3.83 | 1.24 |
| 2005-06-17 | Nate Robertson | R | 28 | W 0-4 | vs SFN | 13 | 54 | L | 7.0 | 8 | 4 | 4 | 0 | 1 | 5 | 89 | 30 | 59 | 66% | 2-5 | 4.09 | 1.47 |
| 2005-06-18 | Jason Johnson | R | 32 | L 8-2 | vs SFN | 14 | 180 | W | 8.0 | 9 | 2 | 1 | 0 | 3 | 4 | 106 | 39 | 67 | 63% | 5-5 | 3.07 | 1.23 |
| 2005-06-19 | Mike Maroth | L | 28 | L 10-8 | vs SFN | 15 | 102 | - | 5.0 | 7 | 4 | 4 | 1 | 3 | 2 | 79 | 29 | 50 | 63% | 5-7 | 4.40 | 1.36 |
| 2005-06-21 | Jeremy Bonderman | R | 23 | W 7-2 | @ MIN | 15 | 75 | W | 9.0 | 5 | 2 | 2 | 0 | 2 | 9 | 109 | 28 | 81 | 74% | 9-4 | 3.67 | 1.20 |
| 2005-06-22 | Nate Robertson | R | 28 | W 8-1 | @ MIN | 14 | 55 | W | 9.0 | 5 | 1 | 0 | 0 | 1 | 6 | 101 | 29 | 72 | 71% | 3-5 | 3.66 | 1.38 |
| 2005-06-23 | Jason Johnson | R | 32 | L 2-6 | @ MIN | 15 | 181 | L | 5.2 | 9 | 6 | 5 | 1 | 2 | 3 | 92 | 34 | 58 | 63% | 5-6 | 3.34 | 1.27 |
| 2005-06-24 | Mike Maroth | L | 28 | L 1-2 | @ ARI | 16 | 103 | L | 6.2 | 7 | 2 | 0 | 0 | 1 | 2 | 100 | 37 | 63 | 63% | 5-8 | 4.09 | 1.34 |
| 2005-06-25 | Sean Douglass | R | 26 | W 5-1 | @ ARI | 1 | 16 | W | 6.0 | 4 | 1 | 1 | 1 | 2 | 1 | 100 | 41 | 59 | 59% | 1-0 | 1.50 | 1.00 |
| 2005-06-26 | Jeremy Bonderman | R | 23 | L 7-13 | @ ARI | 16 | 76 | L | 2.0 | 9 | 8 | 8 | 2 | 1 | 1 | 54 | 23 | 31 | 57% | 9-5 | 4.29 | 1.28 |
| 2005-06-28 | Nate Robertson | R | 28 | W 1-2 | vs CHA | 15 | 56 | L | 7.0 | 6 | 2 | 2 | 1 | 2 | 9 | 117 | 43 | 74 | 63% | 3-6 | 3.58 | 1.37 |
| 2005-06-29 | Jason Johnson | R | 32 | W 3-4 | vs CHA | 16 | 182 | - | 7.0 | 7 | 3 | 3 | 1 | 0 | 2 | 89 | 26 | 63 | 71% | 5-6 | 3.38 | 1.25 |
| 2005-06-30 | Mike Maroth | L | 28 | W 1-6 | vs CHA | 17 | 104 | L | 7.0 | 6 | 5 | 5 | 2 | 2 | 1 | 100 | 36 | 64 | 64% | 5-9 | 4.25 | 1.33 |
| 2005-07-01 | Jeremy Bonderman | R | 23 | L 10-2 | vs NYA | 17 | 77 | W | 9.0 | 8 | 2 | 2 | 1 | 2 | 5 | 116 | 45 | 71 | 61% | 10-5 | 4.11 | 1.26 |
| 2005-07-02 | Sean Douglass | R | 26 | W 4-8 | vs NYA | 2 | 17 | - | 6.0 | 7 | 3 | 1 | 0 | 2 | 6 | 84 | 33 | 51 | 61% | 1-0 | 1.50 | 1.25 |
| 2005-07-03 | Nate Robertson | R | 28 | W 0-1 | vs NYA | 16 | 57 | L | 9.0 | 9 | 1 | 1 | 0 | 1 | 4 | 110 | 34 | 76 | 69% | 3-7 | 3.35 | 1.34 |
| 2005-07-04 | Jason Johnson | R | 32 | L 3-9 | @ CLE | 17 | 183 | L | 3.1 | 11 | 7 | 7 | 1 | 0 | 4 | 80 | 29 | 51 | 64% | 5-7 | 3.87 | 1.32 |
| 2005-07-04 | Justin Verlander | R | 22 | L 0-6 | @ CLE | 1 | 1 | L | 5.1 | 7 | 4 | 4 | 0 | 3 | 4 | 104 | 46 | 58 | 56% | 0-1 | 7.20 | 2.00 |
| 2005-07-05 | Mike Maroth | L | 28 | W 3-2 | @ CLE | 18 | 105 | W | 6.2 | 4 | 1 | 1 | 1 | 2 | 4 | 99 | 42 | 57 | 58% | 6-9 | 4.06 | 1.30 |
| 2005-07-06 | Jeremy Bonderman | R | 23 | W 7-3 | @ CLE | 18 | 78 | W | 8.0 | 5 | 2 | 2 | 1 | 2 | 5 | 103 | 36 | 67 | 65% | 11-5 | 3.98 | 1.24 |
| 2005-07-07 | Sean Douglass | R | 26 | W 6-4 | @ TBA | 3 | 18 | W | 5.0 | 5 | 3 | 3 | 0 | 1 | 4 | 86 | 26 | 60 | 70% | 2-0 | 2.65 | 1.24 |
| 2005-07-08 | Franklyn German | R | 25 | W 7-3 | @ TBA | 1 | 1 | W | 3.0 | 1 | 0 | 0 | 0 | 2 | 1 | 37 | 17 | 20 | 54% | 3-0 | 1.85 | 1.21 |
| 2005-07-09 | Jason Johnson | R | 32 | L 4-5 | @ TBA | 18 | 184 | - | 7.0 | 8 | 3 | 3 | 0 | 0 | 2 | 92 | 30 | 62 | 67% | 5-7 | 3.87 | 1.31 |
| 2005-07-10 | Mike Maroth | L | 28 | W 9-4 | @ TBA | 19 | 106 | W | 5.1 | 10 | 4 | 4 | 1 | 1 | 5 | 90 | 33 | 57 | 63% | 7-9 | 4.19 | 1.34 |
| 2005-07-14 | Jeremy Bonderman | R | 23 | W 9-12 | vs KCA | 19 | 79 | L | 6.0 | 8 | 6 | 6 | 1 | 2 | 9 | 92 | 31 | 61 | 66% | 11-6 | 4.22 | 1.26 |
| 2005-07-15 | Nate Robertson | R | 28 | L 4-1 | vs KCA | 17 | 58 | W | 5.0 | 5 | 1 | 1 | 1 | 2 | 3 | 97 | 34 | 63 | 65% | 4-7 | 3.28 | 1.35 |
| 2005-07-16 | Jason Johnson | R | 32 | L 5-3 | vs KCA | 19 | 185 | W | 8.0 | 7 | 3 | 3 | 2 | 1 | 4 | 109 | 36 | 73 | 67% | 6-7 | 3.84 | 1.29 |
| 2005-07-17 | Mike Maroth | L | 28 | W 0-5 | vs KCA | 20 | 107 | L | 6.1 | 9 | 4 | 3 | 2 | 1 | 4 | 100 | 34 | 66 | 66% | 7-10 | 4.21 | 1.35 |
| 2005-07-18 | Sean Douglass | R | 26 | L 5-7 | @ CHA | 4 | 19 | - | 6.0 | 3 | 1 | 1 | 0 | 2 | 6 | 105 | 43 | 62 | 59% | 2-0 | 2.35 | 1.13 |
| 2005-07-19 | Jeremy Bonderman | R | 23 | W 7-1 | @ CHA | 20 | 80 | W | 8.0 | 3 | 1 | 1 | 0 | 2 | 5 | 114 | 50 | 64 | 56% | 12-6 | 4.04 | 1.22 |
| 2005-07-20 | Nate Robertson | R | 28 | W 8-6 | @ CHA | 18 | 59 | W | 7.0 | 4 | 3 | 3 | 2 | 2 | 6 | 98 | 34 | 64 | 65% | 5-7 | 3.32 | 1.32 |
| 2005-07-21 | Jason Johnson | R | 32 | W 5-10 | vs MIN | 20 | 186 | L | 4.0 | 10 | 8 | 6 | 0 | 2 | 1 | 84 | 29 | 55 | 65% | 6-8 | 4.14 | 1.34 |
| 2005-07-22 | Mike Maroth | L | 28 | L 12-6 | vs MIN | 21 | 108 | W | 6.0 | 8 | 6 | 6 | 2 | 2 | 7 | 104 | 40 | 64 | 62% | 8-10 | 4.43 | 1.37 |
| 2005-07-23 | Sean Douglass | R | 26 | L 2-1 | vs MIN | 5 | 20 | W | 7.0 | 5 | 1 | 1 | 0 | 4 | 1 | 94 | 37 | 57 | 61% | 3-0 | 2.10 | 1.17 |
| 2005-07-23 | Justin Verlander | R | 22 | W 2-5 | vs MIN | 2 | 2 | L | 6.0 | 8 | 5 | 5 | 1 | 2 | 3 | 86 | 26 | 60 | 70% | 0-2 | 7.36 | 1.82 |
| 2005-07-24 | Jeremy Bonderman | R | 23 | L 5-2 | vs MIN | 21 | 81 | W | 8.0 | 7 | 2 | 2 | 1 | 2 | 6 | 97 | 30 | 67 | 69% | 13-6 | 3.94 | 1.22 |
| 2005-07-25 | Nate Robertson | R | 28 | L 3-5 | @ SEA | 19 | 60 | L | 6.1 | 9 | 5 | 5 | 2 | 2 | 6 | 88 | 33 | 55 | 63% | 5-8 | 3.53 | 1.34 |
| 2005-07-26 | Jason Johnson | R | 32 | W 8-5 | @ SEA | 21 | 187 | W | 8.0 | 9 | 5 | 4 | 0 | 3 | 4 | 106 | 39 | 67 | 63% | 7-8 | 4.16 | 1.35 |
| 2005-07-27 | Mike Maroth | L | 28 | L 3-9 | @ SEA | 22 | 109 | L | 1.2 | 5 | 6 | 3 | 0 | 4 | 0 | 55 | 26 | 29 | 53% | 8-11 | 4.57 | 1.42 |
| 2005-07-29 | Sean Douglass | R | 26 | L 4-8 | @ OAK | 6 | 21 | L | 2.2 | 6 | 7 | 7 | 1 | 1 | 0 | 78 | 34 | 44 | 56% | 3-1 | 3.82 | 1.27 |
| 2005-07-30 | Nate Robertson | R | 28 | L 5-9 | @ OAK | 20 | 61 | L | 6.0 | 9 | 7 | 7 | 2 | 1 | 2 | 89 | 34 | 55 | 62% | 5-9 | 3.86 | 1.36 |
| 2005-07-31 | Jeremy Bonderman | R | 23 | L 2-5 | @ OAK | 22 | 82 | L | 6.0 | 8 | 4 | 4 | 1 | 4 | 1 | 100 | 35 | 65 | 65% | 13-7 | 4.02 | 1.25 |
| 2005-08-02 | Jason Johnson | R | 32 | W 1-4 | vs SEA | 22 | 188 | L | 7.2 | 5 | 4 | 4 | 1 | 3 | 1 | 100 | 43 | 57 | 57% | 7-9 | 4.18 | 1.33 |
| 2005-08-03 | Mike Maroth | L | 28 | L 10-7 | vs SEA | 23 | 110 | W | 6.0 | 7 | 5 | 5 | 1 | 1 | 3 | 96 | 33 | 63 | 66% | 9-11 | 4.70 | 1.41 |
| 2005-08-04 | Sean Douglass | R | 26 | L 3-1 | vs SEA | 7 | 22 | W | 8.0 | 3 | 1 | 1 | 1 | 2 | 4 | 100 | 36 | 64 | 64% | 4-1 | 3.29 | 1.15 |
| 2005-08-05 | Nate Robertson | R | 28 | W 6-9 | vs CLE | 21 | 62 | L | 5.0 | 10 | 6 | 6 | 2 | 0 | 4 | 76 | 27 | 49 | 64% | 5-10 | 4.12 | 1.38 |
| 2005-08-06 | Jeremy Bonderman | R | 23 | W 2-4 | vs CLE | 23 | 83 | L | 6.0 | 9 | 3 | 3 | 0 | 2 | 6 | 103 | 40 | 63 | 61% | 13-8 | 4.04 | 1.27 |
| 2005-08-07 | Jason Johnson | R | 32 | W 5-6 | vs CLE | 23 | 189 | - | 7.0 | 6 | 3 | 1 | 2 | 0 | 5 | 93 | 29 | 64 | 69% | 7-9 | 4.05 | 1.31 |
| 2005-08-08 | Mike Maroth | L | 28 | W 9-8 | @ TOR | 24 | 111 | - | 5.2 | 10 | 6 | 6 | 2 | 0 | 1 | 79 | 19 | 60 | 76% | 9-11 | 4.88 | 1.42 |
| 2005-08-09 | Sean Douglass | R | 26 | L 4-6 | @ TOR | 8 | 23 | L | 5.2 | 7 | 6 | 6 | 2 | 0 | 2 | 93 | 38 | 55 | 59% | 4-2 | 4.11 | 1.17 |
| 2005-08-10 | Nate Robertson | R | 28 | L 3-4 | @ TOR | 22 | 63 | - | 7.0 | 8 | 3 | 3 | 1 | 1 | 4 | 108 | 47 | 61 | 56% | 5-10 | 4.11 | 1.38 |
| 2005-08-11 | Jeremy Bonderman | R | 23 | L 1-2 | @ TOR | 24 | 84 | L | 8.0 | 4 | 2 | 2 | 1 | 3 | 8 | 117 | 39 | 78 | 67% | 13-9 | 3.95 | 1.25 |
| 2005-08-14 | Jason Johnson | R | 32 | W 8-7 | @ KCA | 24 | 190 | - | 6.1 | 8 | 6 | 6 | 1 | 2 | 1 | 102 | 44 | 58 | 57% | 7-9 | 4.24 | 1.32 |
| 2005-08-14 | Mike Maroth | L | 28 | W 1-0 | @ KCA | 25 | 112 | W | 8.2 | 5 | 0 | 0 | 0 | 2 | 1 | 108 | 45 | 63 | 58% | 10-11 | 4.62 | 1.39 |
| 2005-08-15 | Sean Douglass | R | 26 | L 7-6 | vs BOS | 9 | 24 | - | 4.0 | 5 | 5 | 5 | 1 | 4 | 1 | 79 | 34 | 45 | 57% | 4-2 | 4.68 | 1.26 |
| 2005-08-16 | Nate Robertson | R | 28 | W 7-10 | vs BOS | 23 | 64 | - | 8.0 | 2 | 2 | 2 | 1 | 3 | 5 | 90 | 33 | 57 | 63% | 5-10 | 4.01 | 1.34 |
| 2005-08-17 | Jeremy Bonderman | R | 23 | L 6-5 | vs BOS | 25 | 85 | W | 6.1 | 9 | 4 | 4 | 0 | 4 | 5 | 106 | 35 | 71 | 67% | 14-9 | 4.02 | 1.28 |
| 2005-08-19 | Mike Maroth | L | 28 | L 9-5 | vs TOR | 26 | 113 | W | 6.2 | 10 | 4 | 4 | 1 | 1 | 6 | 114 | 40 | 74 | 65% | 11-11 | 4.64 | 1.40 |
| 2005-08-20 | Jason Johnson | R | 32 | L 3-2 | vs TOR | 25 | 191 | - | 8.0 | 4 | 2 | 1 | 0 | 3 | 2 | 117 | 46 | 71 | 61% | 7-9 | 4.09 | 1.30 |
| 2005-08-21 | Sean Douglass | R | 26 | L 17-6 | vs TOR | 10 | 25 | W | 6.1 | 8 | 4 | 4 | 2 | 1 | 4 | 106 | 39 | 67 | 63% | 5-2 | 4.74 | 1.26 |
| 2005-08-23 | Nate Robertson | R | 28 | L 4-1 | vs OAK | 24 | 65 | W | 8.0 | 2 | 1 | 1 | 0 | 2 | 6 | 116 | 41 | 75 | 65% | 6-10 | 3.86 | 1.29 |
| 2005-08-24 | Jeremy Bonderman | R | 23 | W 2-9 | vs OAK | 26 | 86 | L | 3.0 | 9 | 6 | 6 | 1 | 1 | 2 | 80 | 33 | 47 | 59% | 14-10 | 4.27 | 1.32 |
| 2005-08-25 | Mike Maroth | L | 28 | W 1-11 | vs OAK | 27 | 114 | L | 3.2 | 10 | 8 | 8 | 1 | 0 | 1 | 84 | 28 | 56 | 67% | 11-12 | 4.97 | 1.43 |
| 2005-08-26 | Jason Johnson | R | 32 | L 8-9 | @ BOS | 26 | 192 | L | 5.2 | 9 | 9 | 9 | 0 | 4 | 3 | 103 | 44 | 59 | 57% | 7-10 | 4.42 | 1.33 |
| 2005-08-27 | Sean Douglass | R | 26 | W 12-8 | @ BOS | 11 | 26 | - | 3.0 | 9 | 7 | 7 | 2 | 2 | 3 | 69 | 26 | 43 | 62% | 5-2 | 5.55 | 1.38 |
| 2005-08-28 | Nate Robertson | R | 28 | L 3-11 | @ BOS | 25 | 66 | L | 5.2 | 9 | 8 | 8 | 1 | 3 | 5 | 97 | 35 | 62 | 64% | 6-11 | 4.16 | 1.32 |
| 2005-08-29 | Jeremy Bonderman | R | 23 | L 8-10 | @ CLE | 27 | 87 | L | 3.1 | 9 | 9 | 5 | 0 | 2 | 1 | 80 | 30 | 50 | 63% | 14-11 | 4.45 | 1.36 |
| 2005-08-31 | Mike Maroth | L | 28 | W 4-3 | @ CLE | 28 | 115 | W | 7.0 | 3 | 2 | 2 | 0 | 2 | 6 | 101 | 43 | 58 | 57% | 12-12 | 4.87 | 1.40 |
| 2005-09-01 | Jason Johnson | R | 32 | L 3-12 | @ CHA | 27 | 193 | L | 5.1 | 11 | 6 | 6 | 2 | 0 | 2 | 74 | 27 | 47 | 64% | 7-11 | 4.60 | 1.36 |
| 2005-09-02 | Sean Douglass | R | 26 | L 1-9 | @ CHA | 12 | 27 | L | 3.2 | 8 | 8 | 8 | 2 | 3 | 4 | 82 | 33 | 49 | 60% | 5-3 | 6.43 | 1.49 |
| 2005-09-03 | Nate Robertson | R | 28 | L 2-6 | @ CHA | 26 | 67 | L | 6.1 | 12 | 6 | 6 | 2 | 2 | 6 | 109 | 36 | 73 | 67% | 6-12 | 4.34 | 1.36 |
| 2005-09-04 | Jeremy Bonderman | R | 23 | L 0-2 | @ CHA | 28 | 88 | L | 8.0 | 5 | 2 | 2 | 1 | 1 | 6 | 114 | 34 | 80 | 70% | 14-12 | 4.35 | 1.33 |
| 2005-09-05 | Mike Maroth | L | 28 | W 0-2 | vs CLE | 29 | 116 | L | 6.0 | 5 | 2 | 2 | 1 | 1 | 6 | 110 | 42 | 68 | 62% | 12-13 | 4.81 | 1.39 |
| 2005-09-06 | Jason Johnson | R | 32 | W 1-6 | vs CLE | 28 | 194 | L | 6.0 | 5 | 2 | 2 | 1 | 2 | 2 | 103 | 41 | 62 | 60% | 7-12 | 4.55 | 1.35 |
| 2005-09-07 | Roman Colon | R | 26 | W 1-4 | vs CLE | 5 | 5 | L | 4.0 | 5 | 3 | 3 | 2 | 1 | 0 | 76 | 28 | 48 | 63% | 2-6 | 5.91 | 1.44 |
| 2005-09-08 | Nate Robertson | R | 28 | L 2-4 | @ CLE | 27 | 68 | L | 7.0 | 5 | 4 | 4 | 3 | 2 | 4 | 103 | 34 | 69 | 67% | 6-13 | 4.37 | 1.34 |
| 2005-09-09 | Sean Douglass | R | 26 | W 2-12 | vs KCA | 13 | 28 | L | 2.0 | 4 | 4 | 4 | 1 | 1 | 4 | 46 | 16 | 30 | 65% | 5-4 | 6.68 | 1.52 |
| 2005-09-10 | Mike Maroth | L | 28 | L 4-3 | vs KCA | 30 | 117 | - | 6.0 | 7 | 3 | 3 | 0 | 1 | 3 | 84 | 30 | 54 | 64% | 12-13 | 4.80 | 1.38 |
| 2005-09-11 | Jason Johnson | R | 32 | L 14-4 | vs KCA | 29 | 195 | W | 5.0 | 8 | 3 | 3 | 0 | 0 | 4 | 66 | 19 | 47 | 71% | 8-12 | 4.57 | 1.36 |
| 2005-09-12 | Roman Colon | R | 26 | W 1-2 | vs MIN | 6 | 6 | - | 5.0 | 9 | 1 | 1 | 0 | 1 | 2 | 88 | 34 | 54 | 61% | 2-6 | 5.61 | 1.48 |
| 2005-09-13 | Nate Robertson | R | 28 | W 3-9 | vs MIN | 28 | 69 | L | 3.0 | 7 | 7 | 5 | 2 | 1 | 1 | 60 | 19 | 41 | 68% | 6-14 | 4.55 | 1.36 |
| 2005-09-14 | Sean Douglass | R | 26 | L 4-2 | vs MIN | 14 | 29 | - | 6.0 | 4 | 1 | 1 | 0 | 1 | 3 | 88 | 28 | 60 | 68% | 5-4 | 6.25 | 1.46 |
| 2005-09-15 | Mike Maroth | L | 28 | W 8-6 | @ ANA | 31 | 118 | W | 6.0 | 7 | 6 | 6 | 3 | 2 | 2 | 96 | 36 | 60 | 63% | 13-13 | 4.93 | 1.39 |
| 2005-09-16 | Jason Johnson | R | 32 | L 6-7 | @ ANA | 30 | 196 | - | 6.0 | 10 | 4 | 4 | 0 | 1 | 2 | 95 | 34 | 61 | 64% | 8-12 | 4.62 | 1.37 |
| 2005-09-17 | Roman Colon | R | 26 | L 1-3 | @ ANA | 7 | 7 | - | 0.2 | 0 | 0 | 0 | 0 | 1 | 1 | 14 | 7 | 7 | 50% | 2-6 | 5.61 | 1.49 |
| 2005-09-18 | Matt Ginter | R | 28 | L 3-5 | @ ANA | 1 | 15 | L | 4.1 | 10 | 5 | 5 | 0 | 1 | 1 | 68 | 25 | 43 | 63% | 0-1 | 6.17 | 1.66 |
| 2005-09-19 | Jeremy Bonderman | R | 23 | L 4-10 | @ KCA | 29 | 89 | L | 4.2 | 11 | 7 | 7 | 1 | 0 | 3 | 71 | 21 | 50 | 70% | 14-13 | 4.57 | 1.35 |
| 2005-09-20 | Mike Maroth | L | 28 | L 4-5 | @ KCA | 32 | 119 | - | 7.0 | 8 | 4 | 2 | 0 | 1 | 3 | 105 | 39 | 66 | 63% | 13-13 | 4.85 | 1.38 |
| 2005-09-20 | Nate Robertson | R | 28 | L 2-4 | @ KCA | 29 | 70 | L | 7.0 | 6 | 4 | 3 | 2 | 1 | 2 | 90 | 25 | 65 | 72% | 6-15 | 4.52 | 1.35 |
| 2005-09-21 | Jason Johnson | R | 32 | L 3-4 | @ KCA | 31 | 197 | - | 6.0 | 5 | 2 | 2 | 1 | 1 | 1 | 102 | 35 | 67 | 66% | 8-12 | 4.57 | 1.36 |
| 2005-09-23 | Sean Douglass | R | 26 | W 1-2 | vs SEA | 15 | 30 | - | 6.0 | 4 | 1 | 1 | 0 | 4 | 5 | 97 | 44 | 53 | 55% | 5-4 | 5.60 | 1.39 |
| 2005-09-24 | Jason Grilli | R | 29 | L 7-1 | vs SEA | 1 | 15 | W | 7.0 | 2 | 1 | 1 | 0 | 4 | 4 | 96 | 36 | 60 | 63% | 1-0 | 2.00 | 1.11 |
| 2005-09-25 | Mike Maroth | L | 28 | L 8-1 | vs SEA | 33 | 120 | W | 7.0 | 4 | 1 | 1 | 0 | 2 | 3 | 91 | 34 | 57 | 63% | 14-13 | 4.72 | 1.37 |
| 2005-09-26 | Jason Johnson | R | 32 | L 4-3 | vs CHA | 32 | 198 | - | 7.0 | 6 | 3 | 3 | 2 | 0 | 1 | 94 | 34 | 60 | 64% | 8-12 | 4.54 | 1.34 |
| 2005-09-27 | Nate Robertson | R | 28 | L 3-2 | vs CHA | 30 | 71 | W | 6.1 | 5 | 1 | 1 | 0 | 5 | 5 | 98 | 43 | 55 | 56% | 7-15 | 4.41 | 1.35 |
| 2005-09-28 | Sean Douglass | R | 26 | W 2-8 | vs CHA | 16 | 31 | L | 5.2 | 9 | 4 | 3 | 0 | 2 | 2 | 93 | 27 | 66 | 71% | 5-5 | 5.59 | 1.44 |
| 2005-09-29 | Jason Grilli | R | 29 | W 2-4 | vs CHA | 2 | 16 | L | 7.0 | 8 | 4 | 4 | 1 | 2 | 0 | 83 | 29 | 54 | 65% | 1-1 | 3.38 | 1.25 |
| 2005-09-30 | Mike Maroth | L | 28 | L 3-7 | @ MIN | 34 | 121 | L | 7.1 | 9 | 4 | 4 | 1 | 1 | 3 | 116 | 47 | 69 | 59% | 14-14 | 4.74 | 1.37 |
| 2005-10-01 | Jason Johnson | R | 32 | L 0-3 | @ MIN | 33 | 199 | L | 6.0 | 6 | 3 | 3 | 0 | 2 | 5 | 88 | 35 | 53 | 60% | 8-13 | 4.54 | 1.34 |
| 2005-10-02 | Nate Robertson | R | 28 | L 4-6 | @ MIN | 31 | 72 | L | 7.0 | 10 | 5 | 5 | 1 | 0 | 4 | 103 | 39 | 64 | 62% | 7-16 | 4.48 | 1.36 |