| Central | W | L | Pct | GB |
| St. Louis | 95 | 67 | .586 | -- |
| Cincinnati | 85 | 77 | .525 | 10.0 |
| Milwaukee | 73 | 89 | .451 | 22.0 |
| Houston | 72 | 90 | .444 | 23.0 |
| Pittsburgh | 69 | 93 | .426 | 26.0 |
| Chi Cubs | 65 | 97 | .401 | 30.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 2000-04-03 | Pete Harnisch | R | 34 | L 3-3 | vs MIL | 1 | 290 | - | 4.0 | 7 | 3 | 2 | 0 | 3 | 1 | 80 | 35 | 45 | 56% | 0-0 | 4.50 | 2.50 |
| 2000-04-04 | Denny Neagle | L | 32 | W 1-5 | vs MIL | 1 | 189 | - | 6.0 | 5 | 1 | 1 | 1 | 1 | 4 | 95 | 37 | 58 | 61% | 0-0 | 1.50 | 1.00 |
| 2000-04-05 | Steve Parris | R | 32 | W 5-8 | vs MIL | 1 | 57 | L | 5.0 | 5 | 5 | 5 | 1 | 1 | 3 | 89 | 38 | 51 | 57% | 0-1 | 9.00 | 1.20 |
| 2000-04-06 | Ron Villone | L | 30 | L 5-1 | vs MIL | 1 | 23 | W | 5.2 | 7 | 1 | 1 | 0 | 2 | 3 | 107 | 43 | 64 | 60% | 1-0 | 1.50 | 1.50 |
| 2000-04-07 | Pete Harnisch | R | 34 | W 6-10 | vs CHN | 2 | 291 | L | 4.0 | 6 | 6 | 6 | 2 | 3 | 6 | 80 | 35 | 45 | 56% | 0-1 | 9.00 | 2.38 |
| 2000-04-08 | Rob Bell | R | 23 | L 4-3 | vs CHN | 1 | 1 | - | 7.0 | 3 | 3 | 1 | 0 | 2 | 9 | 91 | 28 | 63 | 69% | 0-0 | 1.29 | 0.71 |
| 2000-04-09 | Denny Neagle | L | 32 | L 8-7 | vs CHN | 2 | 190 | - | 5.2 | 8 | 6 | 6 | 3 | 4 | 2 | 96 | 39 | 57 | 59% | 0-0 | 5.25 | 1.50 |
| 2000-04-10 | Steve Parris | R | 32 | L 5-7 | @ COL | 2 | 58 | L | 4.0 | 8 | 5 | 5 | 1 | 2 | 5 | 86 | 32 | 54 | 63% | 0-2 | 10.00 | 1.78 |
| 2000-04-11 | Ron Villone | L | 30 | W 10-3 | @ COL | 2 | 24 | W | 7.0 | 4 | 2 | 2 | 0 | 4 | 4 | 122 | 53 | 69 | 57% | 2-0 | 2.08 | 1.31 |
| 2000-04-12 | Pete Harnisch | R | 34 | L 5-7 | @ COL | 3 | 292 | - | 6.0 | 5 | 4 | 3 | 0 | 2 | 3 | 94 | 35 | 59 | 63% | 0-1 | 7.07 | 1.86 |
| 2000-04-14 | Rob Bell | R | 23 | L 1-8 | @ LAN | 2 | 2 | L | 5.1 | 4 | 2 | 1 | 1 | 1 | 6 | 73 | 27 | 46 | 63% | 0-1 | 1.50 | 0.83 |
| 2000-04-15 | Denny Neagle | L | 32 | W 5-4 | @ LAN | 3 | 191 | - | 5.1 | 4 | 3 | 3 | 1 | 5 | 5 | 108 | 44 | 64 | 59% | 0-0 | 5.29 | 1.59 |
| 2000-04-16 | Steve Parris | R | 32 | W 5-3 | @ LAN | 3 | 59 | W | 6.0 | 3 | 1 | 1 | 1 | 4 | 0 | 94 | 41 | 53 | 56% | 1-2 | 6.60 | 1.53 |
| 2000-04-18 | Ron Villone | L | 30 | W 9-13 | vs SFN | 3 | 25 | - | 2.2 | 8 | 4 | 3 | 2 | 1 | 1 | 64 | 25 | 39 | 61% | 2-0 | 3.60 | 1.73 |
| 2000-04-19 | Rob Bell | R | 23 | L 5-4 | vs SFN | 3 | 3 | W | 5.2 | 6 | 4 | 4 | 1 | 3 | 2 | 104 | 42 | 62 | 60% | 1-1 | 3.00 | 1.06 |
| 2000-04-20 | Denny Neagle | L | 32 | L 11-1 | vs SFN | 4 | 192 | W | 8.0 | 6 | 1 | 1 | 0 | 3 | 4 | 122 | 47 | 75 | 61% | 1-0 | 3.96 | 1.44 |
| 2000-04-21 | Steve Parris | R | 32 | W 2-9 | vs LAN | 4 | 60 | L | 2.0 | 7 | 5 | 5 | 1 | 2 | 2 | 84 | 34 | 50 | 60% | 1-3 | 8.47 | 1.88 |
| 2000-04-22 | Pete Harnisch | R | 34 | W 2-16 | vs LAN | 4 | 293 | L | 4.2 | 8 | 9 | 9 | 3 | 5 | 6 | 104 | 50 | 54 | 52% | 0-2 | 9.47 | 2.05 |
| 2000-04-23 | Ron Villone | L | 30 | W 3-11 | vs LAN | 4 | 26 | L | 5.1 | 7 | 6 | 5 | 1 | 3 | 2 | 96 | 47 | 49 | 51% | 2-1 | 4.71 | 1.71 |
| 2000-04-25 | Rob Bell | R | 23 | L 5-6 | @ NYN | 4 | 4 | - | 4.0 | 5 | 4 | 4 | 2 | 2 | 2 | 63 | 21 | 42 | 67% | 1-1 | 4.09 | 1.18 |
| 2000-04-26 | Denny Neagle | L | 32 | W 12-1 | @ NYN | 5 | 193 | W | 7.0 | 2 | 0 | 0 | 0 | 4 | 9 | 115 | 45 | 70 | 61% | 2-0 | 3.09 | 1.31 |
| 2000-04-27 | Steve Parris | R | 32 | W 2-1 | @ NYN | 5 | 61 | - | 7.0 | 4 | 1 | 1 | 1 | 3 | 2 | 91 | 41 | 50 | 55% | 1-3 | 6.38 | 1.63 |
| 2000-04-28 | Pete Harnisch | R | 34 | L 1-2 | @ PIT | 5 | 294 | L | 6.1 | 5 | 2 | 2 | 1 | 4 | 4 | 104 | 44 | 60 | 58% | 0-3 | 7.92 | 1.92 |
| 2000-04-29 | Ron Villone | L | 30 | W 6-5 | @ PIT | 5 | 27 | - | 5.0 | 6 | 4 | 4 | 1 | 3 | 1 | 97 | 42 | 55 | 57% | 2-1 | 5.19 | 1.73 |
| 2000-04-30 | Rob Bell | R | 23 | W 6-2 | @ PIT | 5 | 5 | W | 6.0 | 4 | 2 | 2 | 0 | 5 | 7 | 109 | 49 | 60 | 55% | 2-1 | 3.86 | 1.25 |
| 2000-05-02 | Denny Neagle | L | 32 | W 7-0 | @ PHI | 6 | 194 | W | 6.0 | 1 | 0 | 0 | 0 | 4 | 5 | 102 | 39 | 63 | 62% | 3-0 | 2.61 | 1.24 |
| 2000-05-03 | Steve Parris | R | 32 | L 2-5 | @ PHI | 6 | 62 | L | 5.0 | 7 | 4 | 3 | 0 | 2 | 4 | 99 | 40 | 59 | 60% | 1-4 | 6.21 | 1.66 |
| 2000-05-04 | Pete Harnisch | R | 34 | L 1-14 | @ PHI | 6 | 295 | L | 0.1 | 6 | 6 | 6 | 1 | 0 | 1 | 33 | 11 | 22 | 67% | 0-4 | 10.08 | 2.16 |
| 2000-05-05 | Ron Villone | L | 30 | L 3-2 | vs SLN | 6 | 28 | W | 6.2 | 5 | 2 | 2 | 2 | 3 | 4 | 100 | 40 | 60 | 60% | 3-1 | 4.78 | 1.66 |
| 2000-05-06 | Rob Bell | R | 23 | W 1-3 | vs SLN | 6 | 6 | L | 7.0 | 5 | 2 | 2 | 1 | 3 | 6 | 99 | 33 | 66 | 67% | 2-2 | 3.60 | 1.23 |
| 2000-05-07 | Denny Neagle | L | 32 | L 9-7 | vs SLN | 7 | 195 | W | 6.0 | 9 | 7 | 7 | 2 | 2 | 4 | 94 | 30 | 64 | 68% | 4-0 | 3.68 | 1.32 |
| 2000-05-09 | Steve Parris | R | 32 | L 2-0 | vs SDN | 7 | 63 | W | 6.0 | 5 | 0 | 0 | 0 | 1 | 3 | 92 | 35 | 57 | 62% | 2-4 | 5.14 | 1.54 |
| 2000-05-10 | Ron Villone | L | 30 | L 5-1 | vs SDN | 7 | 29 | W | 6.1 | 5 | 1 | 1 | 1 | 2 | 2 | 104 | 43 | 61 | 59% | 4-1 | 4.15 | 1.54 |
| 2000-05-11 | Rob Bell | R | 23 | L 11-9 | vs SDN | 7 | 7 | - | 2.0 | 5 | 5 | 5 | 1 | 1 | 1 | 53 | 19 | 34 | 64% | 2-2 | 4.62 | 1.32 |
| 2000-05-12 | Denny Neagle | L | 32 | W 7-3 | @ HOU | 8 | 196 | - | 5.0 | 5 | 3 | 2 | 0 | 4 | 5 | 124 | 56 | 68 | 55% | 4-0 | 3.67 | 1.37 |
| 2000-05-13 | Osvaldo Fernandez | R | 32 | W 8-7 | @ HOU | 1 | 40 | - | 6.1 | 6 | 4 | 4 | 2 | 2 | 4 | 91 | 34 | 57 | 63% | 0-0 | 6.00 | 1.33 |
| 2000-05-14 | Steve Parris | R | 32 | L 3-10 | @ HOU | 8 | 64 | L | 6.0 | 10 | 6 | 6 | 1 | 4 | 3 | 123 | 56 | 67 | 54% | 2-5 | 5.71 | 1.66 |
| 2000-05-15 | Ron Villone | L | 30 | W 4-3 | @ HOU | 8 | 30 | W | 7.0 | 2 | 1 | 1 | 1 | 5 | 3 | 110 | 50 | 60 | 55% | 5-1 | 3.72 | 1.46 |
| 2000-05-16 | Rob Bell | R | 23 | L 6-2 | vs PIT | 8 | 8 | W | 6.0 | 6 | 1 | 1 | 0 | 3 | 3 | 91 | 39 | 52 | 57% | 3-2 | 4.19 | 1.35 |
| 2000-05-17 | Denny Neagle | L | 32 | W 6-9 | vs PIT | 9 | 197 | - | 6.0 | 8 | 3 | 3 | 0 | 1 | 6 | 100 | 37 | 63 | 63% | 4-0 | 3.76 | 1.38 |
| 2000-05-18 | Osvaldo Fernandez | R | 32 | L 4-3 | vs PIT | 2 | 41 | - | 6.0 | 7 | 3 | 3 | 0 | 2 | 0 | 90 | 36 | 54 | 60% | 0-0 | 5.25 | 1.42 |
| 2000-05-19 | Steve Parris | R | 32 | L 1-4 | @ CHN | 9 | 65 | L | 7.0 | 7 | 4 | 4 | 0 | 1 | 3 | 98 | 38 | 60 | 61% | 2-6 | 5.63 | 1.58 |
| 2000-05-20 | Ron Villone | L | 30 | W 5-3 | @ CHN | 9 | 31 | W | 6.0 | 9 | 3 | 3 | 0 | 3 | 2 | 129 | 55 | 74 | 57% | 6-1 | 3.81 | 1.52 |
| 2000-05-21 | Rob Bell | R | 23 | L 2-4 | @ CHN | 9 | 9 | L | 6.0 | 3 | 3 | 3 | 1 | 1 | 5 | 66 | 22 | 44 | 67% | 3-3 | 4.22 | 1.27 |
| 2000-05-22 | Denny Neagle | L | 32 | L 3-4 | @ LAN | 10 | 198 | - | 7.0 | 4 | 2 | 2 | 2 | 1 | 4 | 87 | 33 | 54 | 62% | 4-0 | 3.63 | 1.31 |
| 2000-05-23 | Osvaldo Fernandez | R | 32 | W 3-1 | @ LAN | 3 | 42 | W | 7.0 | 3 | 1 | 1 | 0 | 2 | 4 | 97 | 29 | 68 | 70% | 1-0 | 3.79 | 1.16 |
| 2000-05-24 | Steve Parris | R | 32 | W 10-3 | @ LAN | 10 | 66 | - | 5.0 | 4 | 3 | 0 | 0 | 1 | 4 | 68 | 21 | 47 | 69% | 2-6 | 5.09 | 1.53 |
| 2000-05-26 | Ron Villone | L | 30 | L 3-2 | vs FLO | 10 | 32 | - | 6.1 | 7 | 2 | 2 | 1 | 3 | 4 | 102 | 39 | 63 | 62% | 6-1 | 3.72 | 1.53 |
| 2000-05-27 | Rob Bell | R | 23 | W 6-8 | vs FLO | 10 | 10 | - | 4.0 | 8 | 4 | 4 | 3 | 3 | 5 | 95 | 33 | 62 | 65% | 3-3 | 4.58 | 1.38 |
| 2000-05-28 | Denny Neagle | L | 32 | W 1-3 | vs FLO | 11 | 199 | - | 7.0 | 5 | 1 | 1 | 0 | 4 | 7 | 120 | 46 | 74 | 62% | 4-0 | 3.39 | 1.30 |
| 2000-05-30 | Osvaldo Fernandez | R | 32 | L 4-2 | vs MON | 4 | 43 | W | 7.0 | 2 | 1 | 1 | 0 | 0 | 5 | 82 | 32 | 50 | 61% | 2-0 | 3.12 | 0.92 |
| 2000-05-31 | Steve Parris | R | 32 | W 4-10 | vs MON | 11 | 67 | L | 5.1 | 6 | 4 | 4 | 1 | 1 | 3 | 86 | 25 | 61 | 71% | 2-7 | 5.28 | 1.52 |
| 2000-06-01 | Ron Villone | L | 30 | W 7-9 | vs MON | 11 | 33 | L | 4.0 | 11 | 8 | 8 | 2 | 2 | 1 | 83 | 34 | 49 | 59% | 6-2 | 4.65 | 1.65 |
| 2000-06-02 | Rob Bell | R | 23 | L 4-3 | vs MIN | 11 | 11 | W | 7.0 | 4 | 1 | 1 | 1 | 2 | 5 | 105 | 42 | 63 | 60% | 4-3 | 4.20 | 1.32 |
| 2000-06-03 | Denny Neagle | L | 32 | L 9-3 | vs MIN | 12 | 200 | W | 7.0 | 4 | 3 | 3 | 1 | 4 | 4 | 103 | 44 | 59 | 57% | 5-0 | 3.43 | 1.29 |
| 2000-06-04 | Osvaldo Fernandez | R | 32 | L 3-2 | vs MIN | 5 | 44 | - | 3.0 | 2 | 0 | 0 | 0 | 1 | 0 | 37 | 17 | 20 | 54% | 2-0 | 2.79 | 0.93 |
| 2000-06-05 | Steve Parris | R | 32 | W 3-4 | vs CHA | 12 | 68 | L | 6.0 | 3 | 2 | 2 | 1 | 2 | 3 | 87 | 35 | 52 | 60% | 2-8 | 5.06 | 1.45 |
| 2000-06-06 | Ron Villone | L | 30 | W 12-17 | vs CHA | 12 | 34 | L | 1.1 | 4 | 7 | 7 | 1 | 3 | 1 | 59 | 25 | 34 | 58% | 6-3 | 5.57 | 1.73 |
| 2000-06-07 | Rob Bell | R | 23 | W 4-6 | vs CHA | 12 | 12 | L | 6.0 | 8 | 4 | 4 | 1 | 3 | 5 | 95 | 35 | 60 | 63% | 4-4 | 4.36 | 1.36 |
| 2000-06-09 | Denny Neagle | L | 32 | L 4-7 | @ CLE | 13 | 201 | L | 6.0 | 11 | 6 | 6 | 3 | 1 | 2 | 115 | 37 | 78 | 68% | 5-1 | 3.84 | 1.34 |
| 2000-06-10 | Steve Parris | R | 33 | L 5-6 | @ CLE | 13 | 69 | L | 6.0 | 10 | 6 | 6 | 4 | 1 | 5 | 117 | 44 | 73 | 62% | 2-9 | 5.40 | 1.49 |
| 2000-06-11 | Ron Villone | L | 30 | W 7-5 | @ CLE | 13 | 35 | - | 6.0 | 8 | 4 | 4 | 0 | 5 | 3 | 118 | 54 | 64 | 54% | 6-3 | 5.61 | 1.77 |
| 2000-06-12 | Rob Bell | R | 23 | L 3-10 | @ SFN | 13 | 13 | L | 4.0 | 4 | 5 | 5 | 3 | 6 | 0 | 88 | 45 | 43 | 49% | 4-5 | 4.76 | 1.43 |
| 2000-06-13 | Osvaldo Fernandez | R | 32 | L 2-3 | @ SFN | 6 | 45 | - | 6.0 | 3 | 1 | 1 | 0 | 6 | 5 | 91 | 44 | 47 | 52% | 2-0 | 2.57 | 1.03 |
| 2000-06-14 | Denny Neagle | L | 32 | L 2-6 | @ SFN | 14 | 202 | L | 6.0 | 10 | 5 | 4 | 0 | 1 | 3 | 97 | 34 | 63 | 65% | 5-2 | 3.99 | 1.38 |
| 2000-06-16 | Steve Parris | R | 33 | L 5-8 | @ SDN | 14 | 70 | L | 3.0 | 6 | 7 | 5 | 2 | 2 | 2 | 67 | 31 | 36 | 54% | 2-10 | 5.79 | 1.53 |
| 2000-06-17 | Ron Villone | L | 30 | L 1-3 | @ SDN | 14 | 36 | L | 7.1 | 4 | 3 | 3 | 1 | 3 | 3 | 108 | 46 | 62 | 57% | 6-4 | 5.38 | 1.68 |
| 2000-06-18 | Rob Bell | R | 23 | L 7-8 | @ SDN | 14 | 14 | L | 0.2 | 1 | 3 | 3 | 0 | 5 | 1 | 40 | 25 | 15 | 38% | 4-6 | 5.07 | 1.49 |
| 2000-06-20 | Osvaldo Fernandez | R | 32 | L 3-2 | vs COL | 7 | 46 | - | 7.1 | 6 | 2 | 2 | 2 | 2 | 3 | 91 | 33 | 58 | 64% | 2-0 | 2.51 | 1.02 |
| 2000-06-21 | Denny Neagle | L | 32 | W 4-6 | vs COL | 15 | 203 | - | 7.0 | 8 | 3 | 3 | 0 | 2 | 6 | 119 | 47 | 72 | 61% | 5-2 | 3.98 | 1.38 |
| 2000-06-22 | Steve Parris | R | 33 | L 5-3 | vs COL | 15 | 71 | W | 7.1 | 5 | 3 | 3 | 0 | 3 | 4 | 124 | 47 | 77 | 62% | 3-10 | 5.56 | 1.48 |
| 2000-06-23 | Rob Bell | R | 23 | W 7-10 | vs SDN | 15 | 15 | - | 4.1 | 5 | 4 | 4 | 2 | 2 | 2 | 74 | 32 | 42 | 57% | 4-6 | 5.28 | 1.51 |
| 2000-06-24 | Ron Villone | L | 30 | L 11-5 | vs SDN | 15 | 37 | W | 5.0 | 8 | 4 | 4 | 2 | 4 | 0 | 94 | 43 | 51 | 54% | 7-4 | 5.49 | 1.72 |
| 2000-06-25 | Osvaldo Fernandez | R | 32 | W 4-5 | vs SDN | 8 | 47 | L | 5.0 | 7 | 5 | 5 | 0 | 5 | 2 | 92 | 39 | 53 | 58% | 2-1 | 3.19 | 1.17 |
| 2000-06-26 | Denny Neagle | L | 32 | L 3-2 | vs SLN | 16 | 204 | W | 7.2 | 7 | 2 | 2 | 1 | 3 | 6 | 117 | 50 | 67 | 57% | 6-2 | 3.84 | 1.37 |
| 2000-06-27 | Steve Parris | R | 33 | W 3-4 | vs SLN | 16 | 72 | L | 5.0 | 8 | 4 | 4 | 2 | 3 | 5 | 114 | 42 | 72 | 63% | 3-11 | 5.65 | 1.52 |
| 2000-06-28 | Elmer Dessens | R | 28 | L 7-3 | vs SLN | 1 | 9 | - | 5.2 | 6 | 3 | 3 | 1 | 4 | 5 | 85 | 36 | 49 | 58% | 0-0 | 5.05 | 1.66 |
| 2000-06-29 | Ron Villone | L | 30 | W 3-12 | vs SLN | 16 | 38 | L | 5.0 | 8 | 7 | 7 | 1 | 3 | 5 | 95 | 37 | 58 | 61% | 7-5 | 5.90 | 1.75 |
| 2000-06-30 | Pete Harnisch | R | 34 | W 5-4 | @ ARI | 7 | 296 | W | 6.0 | 5 | 2 | 2 | 1 | 3 | 5 | 97 | 39 | 58 | 60% | 1-4 | 8.71 | 2.00 |
| 2000-07-01 | Osvaldo Fernandez | R | 32 | L 6-9 | @ ARI | 9 | 48 | L | 2.1 | 7 | 7 | 7 | 1 | 2 | 1 | 49 | 20 | 29 | 59% | 2-2 | 4.32 | 1.30 |
| 2000-07-02 | Denny Neagle | L | 32 | W 14-2 | @ ARI | 17 | 205 | W | 7.0 | 8 | 2 | 2 | 1 | 2 | 5 | 119 | 36 | 83 | 70% | 7-2 | 3.76 | 1.37 |
| 2000-07-03 | Steve Parris | R | 33 | W 3-2 | @ ARI | 17 | 73 | W | 6.2 | 7 | 1 | 1 | 0 | 2 | 6 | 120 | 44 | 76 | 63% | 4-11 | 5.38 | 1.52 |
| 2000-07-04 | Ron Villone | L | 30 | L 3-14 | @ SLN | 17 | 39 | L | 0.2 | 5 | 6 | 1 | 1 | 2 | 0 | 48 | 20 | 28 | 58% | 7-6 | 6.00 | 1.83 |
| 2000-07-05 | Pete Harnisch | R | 34 | L 3-4 | @ SLN | 8 | 297 | L | 7.0 | 5 | 4 | 2 | 2 | 2 | 1 | 94 | 35 | 59 | 63% | 1-5 | 7.58 | 1.82 |
| 2000-07-06 | Osvaldo Fernandez | R | 32 | W 12-6 | @ SLN | 10 | 49 | - | 1.1 | 6 | 3 | 3 | 1 | 1 | 1 | 36 | 14 | 22 | 61% | 2-2 | 4.76 | 1.41 |
| 2000-07-07 | Denny Neagle | L | 32 | L 2-1 | vs CLE | 18 | 206 | W | 8.0 | 6 | 0 | 0 | 0 | 4 | 7 | 137 | 44 | 93 | 68% | 8-2 | 3.51 | 1.36 |
| 2000-07-08 | Steve Parris | R | 33 | L 14-5 | vs CLE | 18 | 74 | W | 7.0 | 5 | 3 | 3 | 3 | 0 | 4 | 97 | 30 | 67 | 69% | 5-11 | 5.27 | 1.46 |
| 2000-07-09 | Scott Williamson | R | 24 | W 3-5 | vs CLE | 1 | 1 | L | 5.2 | 3 | 2 | 2 | 1 | 1 | 7 | 88 | 36 | 52 | 59% | 2-6 | 3.63 | 1.53 |
| 2000-07-13 | Elmer Dessens | R | 28 | W 15-6 | @ COL | 2 | 10 | W | 7.1 | 9 | 6 | 6 | 0 | 3 | 1 | 95 | 43 | 52 | 55% | 2-0 | 4.82 | 1.55 |
| 2000-07-14 | Pete Harnisch | R | 34 | W 9-2 | @ COL | 9 | 298 | W | 9.0 | 5 | 2 | 1 | 1 | 4 | 2 | 132 | 44 | 88 | 67% | 2-5 | 6.32 | 1.66 |
| 2000-07-15 | Scott Williamson | R | 24 | W 7-4 | @ COL | 2 | 2 | W | 6.0 | 5 | 3 | 3 | 0 | 4 | 3 | 96 | 40 | 56 | 58% | 3-6 | 3.71 | 1.53 |
| 2000-07-16 | Steve Parris | R | 33 | L 2-6 | @ DET | 19 | 75 | L | 4.2 | 7 | 6 | 6 | 1 | 2 | 4 | 94 | 44 | 50 | 53% | 5-12 | 5.54 | 1.48 |
| 2000-07-17 | Larry Luebbers | R | 31 | L 1-3 | @ DET | 1 | 23 | L | 6.2 | 7 | 3 | 3 | 0 | 3 | 1 | 101 | 45 | 56 | 55% | 0-1 | 3.86 | 1.43 |
| 2000-07-18 | Elmer Dessens | R | 29 | W 5-4 | @ DET | 3 | 11 | W | 5.2 | 7 | 4 | 4 | 0 | 3 | 0 | 88 | 37 | 51 | 58% | 3-0 | 5.02 | 1.59 |
| 2000-07-19 | Pete Harnisch | R | 34 | W 4-0 | @ HOU | 10 | 299 | W | 9.0 | 4 | 0 | 0 | 0 | 2 | 4 | 111 | 33 | 78 | 70% | 3-5 | 5.30 | 1.50 |
| 2000-07-20 | Scott Williamson | R | 24 | L 2-6 | @ HOU | 3 | 3 | L | 3.0 | 2 | 2 | 1 | 0 | 4 | 4 | 63 | 33 | 30 | 48% | 3-7 | 3.68 | 1.55 |
| 2000-07-21 | Steve Parris | R | 33 | W 4-5 | vs ARI | 20 | 76 | - | 6.0 | 9 | 4 | 4 | 1 | 3 | 2 | 97 | 38 | 59 | 61% | 5-12 | 5.56 | 1.51 |
| 2000-07-22 | Ron Villone | L | 31 | L 7-3 | vs ARI | 18 | 40 | W | 6.0 | 5 | 3 | 2 | 1 | 4 | 3 | 123 | 51 | 72 | 59% | 8-6 | 5.91 | 1.81 |
| 2000-07-23 | Elmer Dessens | R | 29 | L 5-3 | vs ARI | 4 | 12 | W | 7.1 | 8 | 3 | 3 | 1 | 1 | 5 | 92 | 29 | 63 | 68% | 4-0 | 4.83 | 1.54 |
| 2000-07-24 | Pete Harnisch | R | 34 | W 5-7 | vs HOU | 11 | 300 | - | 5.2 | 7 | 4 | 4 | 2 | 3 | 0 | 93 | 41 | 52 | 56% | 3-5 | 5.37 | 1.52 |
| 2000-07-25 | Scott Williamson | R | 24 | W 4-7 | vs HOU | 4 | 4 | - | 6.0 | 6 | 1 | 1 | 0 | 1 | 8 | 114 | 41 | 73 | 64% | 3-7 | 3.51 | 1.52 |
| 2000-07-26 | Steve Parris | R | 33 | W 2-3 | vs HOU | 21 | 77 | L | 7.0 | 9 | 3 | 3 | 3 | 1 | 5 | 112 | 38 | 74 | 66% | 5-13 | 5.46 | 1.50 |
| 2000-07-28 | Elmer Dessens | R | 29 | W 8-3 | @ MON | 5 | 13 | W | 7.0 | 7 | 3 | 3 | 0 | 1 | 2 | 91 | 32 | 59 | 65% | 5-0 | 4.74 | 1.50 |
| 2000-07-29 | Pete Harnisch | R | 34 | W 4-3 | @ MON | 12 | 301 | - | 6.0 | 7 | 3 | 3 | 1 | 1 | 1 | 78 | 29 | 49 | 63% | 3-5 | 5.29 | 1.50 |
| 2000-07-30 | Rob Bell | R | 24 | W 7-4 | @ MON | 16 | 16 | W | 7.2 | 8 | 4 | 4 | 2 | 4 | 9 | 122 | 44 | 78 | 64% | 5-6 | 5.20 | 1.51 |
| 2000-07-31 | Scott Williamson | R | 24 | W 6-0 | @ NYN | 5 | 5 | W | 6.0 | 6 | 0 | 0 | 0 | 2 | 3 | 99 | 40 | 59 | 60% | 4-7 | 3.25 | 1.51 |
| 2000-08-01 | Steve Parris | R | 33 | L 2-3 | @ NYN | 22 | 78 | L | 6.0 | 7 | 3 | 3 | 0 | 3 | 4 | 107 | 41 | 66 | 62% | 5-14 | 5.41 | 1.51 |
| 2000-08-02 | Elmer Dessens | R | 29 | L 1-2 | @ NYN | 6 | 14 | L | 7.0 | 6 | 2 | 2 | 1 | 1 | 5 | 89 | 29 | 60 | 67% | 5-1 | 4.55 | 1.46 |
| 2000-08-04 | Pete Harnisch | R | 34 | W 1-2 | vs FLO | 13 | 302 | L | 8.0 | 8 | 2 | 2 | 0 | 1 | 3 | 118 | 46 | 72 | 61% | 3-6 | 4.97 | 1.46 |
| 2000-08-05 | Rob Bell | R | 24 | W 5-10 | vs FLO | 17 | 17 | - | 6.0 | 5 | 3 | 3 | 2 | 4 | 7 | 107 | 45 | 62 | 58% | 5-6 | 5.16 | 1.51 |
| 2000-08-06 | Scott Williamson | R | 24 | W 6-9 | vs FLO | 6 | 6 | - | 4.0 | 6 | 6 | 5 | 1 | 3 | 5 | 80 | 35 | 45 | 56% | 4-7 | 3.62 | 1.54 |
| 2000-08-07 | Steve Parris | R | 33 | L 3-2 | vs ATL | 23 | 79 | - | 8.0 | 9 | 2 | 2 | 0 | 0 | 4 | 106 | 38 | 68 | 64% | 5-14 | 5.22 | 1.49 |
| 2000-08-08 | Elmer Dessens | R | 29 | W 4-5 | vs ATL | 7 | 15 | L | 6.1 | 10 | 5 | 4 | 0 | 1 | 4 | 81 | 23 | 58 | 72% | 5-2 | 4.65 | 1.48 |
| 2000-08-09 | Pete Harnisch | R | 34 | L 10-6 | vs ATL | 14 | 303 | W | 9.0 | 9 | 6 | 6 | 0 | 1 | 3 | 124 | 41 | 83 | 67% | 4-6 | 5.08 | 1.42 |
| 2000-08-11 | Rob Bell | R | 24 | W 6-4 | @ CHN | 18 | 18 | - | 5.0 | 5 | 4 | 1 | 1 | 3 | 2 | 88 | 39 | 49 | 56% | 5-6 | 4.98 | 1.51 |
| 2000-08-12 | Scott Williamson | R | 24 | W 3-0 | @ CHN | 7 | 7 | W | 7.0 | 4 | 0 | 0 | 0 | 5 | 7 | 121 | 52 | 69 | 57% | 5-7 | 3.35 | 1.52 |
| 2000-08-13 | Steve Parris | R | 33 | W 3-0 | @ CHN | 24 | 80 | W | 7.2 | 6 | 0 | 0 | 0 | 4 | 3 | 106 | 43 | 63 | 59% | 6-14 | 4.92 | 1.47 |
| 2000-08-14 | Elmer Dessens | R | 29 | L 3-4 | @ MIL | 8 | 16 | L | 6.2 | 7 | 4 | 4 | 0 | 2 | 3 | 108 | 43 | 65 | 60% | 5-3 | 4.69 | 1.47 |
| 2000-08-15 | Pete Harnisch | R | 34 | L 1-2 | @ MIL | 15 | 304 | - | 7.0 | 6 | 1 | 1 | 1 | 0 | 3 | 95 | 25 | 70 | 74% | 4-6 | 4.79 | 1.38 |
| 2000-08-16 | Rob Bell | R | 24 | L 1-5 | @ MIL | 19 | 19 | L | 4.1 | 5 | 2 | 2 | 1 | 1 | 6 | 81 | 31 | 50 | 62% | 5-7 | 4.96 | 1.51 |
| 2000-08-18 | Scott Williamson | R | 25 | W 3-6 | vs PIT | 8 | 8 | - | 7.0 | 5 | 2 | 2 | 1 | 2 | 7 | 109 | 46 | 63 | 58% | 5-7 | 3.30 | 1.49 |
| 2000-08-19 | Steve Parris | R | 33 | L 7-1 | vs PIT | 25 | 81 | W | 6.1 | 8 | 1 | 1 | 0 | 2 | 3 | 106 | 41 | 65 | 61% | 7-14 | 4.78 | 1.48 |
| 2000-08-20 | Elmer Dessens | R | 29 | W 3-7 | vs PIT | 9 | 17 | L | 4.1 | 6 | 5 | 5 | 0 | 5 | 5 | 86 | 38 | 48 | 56% | 5-4 | 4.95 | 1.52 |
| 2000-08-21 | Pete Harnisch | R | 34 | L 7-4 | vs PHI | 16 | 305 | W | 5.1 | 9 | 4 | 3 | 0 | 4 | 2 | 93 | 37 | 56 | 60% | 5-6 | 4.82 | 1.44 |
| 2000-08-22 | Rob Bell | R | 24 | W 4-5 | vs PHI | 20 | 20 | - | 7.0 | 6 | 4 | 4 | 2 | 3 | 5 | 98 | 42 | 56 | 57% | 5-7 | 4.97 | 1.50 |
| 2000-08-23 | Scott Williamson | R | 25 | W 3-4 | vs PHI | 9 | 9 | - | 7.0 | 4 | 1 | 1 | 0 | 3 | 8 | 106 | 37 | 69 | 65% | 5-7 | 3.17 | 1.45 |
| 2000-08-24 | Steve Parris | R | 33 | L 8-3 | vs PHI | 26 | 82 | W | 6.2 | 9 | 2 | 2 | 0 | 2 | 5 | 115 | 44 | 71 | 62% | 8-14 | 4.68 | 1.49 |
| 2000-08-25 | Elmer Dessens | R | 29 | W 6-0 | @ FLO | 10 | 18 | W | 7.0 | 7 | 0 | 0 | 0 | 1 | 5 | 117 | 45 | 72 | 62% | 6-4 | 4.63 | 1.50 |
| 2000-08-26 | Pete Harnisch | R | 34 | W 3-2 | @ FLO | 17 | 306 | W | 6.0 | 5 | 1 | 1 | 1 | 2 | 5 | 82 | 26 | 56 | 68% | 6-6 | 4.63 | 1.43 |
| 2000-08-27 | Rob Bell | R | 24 | L 6-7 | @ FLO | 21 | 21 | - | 6.0 | 5 | 3 | 3 | 1 | 5 | 3 | 93 | 45 | 48 | 52% | 5-7 | 4.95 | 1.50 |
| 2000-08-28 | Ron Villone | L | 31 | W 6-3 | @ ATL | 19 | 41 | W | 9.0 | 5 | 3 | 3 | 1 | 3 | 5 | 113 | 41 | 72 | 64% | 9-7 | 5.35 | 1.67 |
| 2000-08-29 | Steve Parris | R | 33 | W 4-2 | @ ATL | 27 | 83 | W | 6.0 | 8 | 2 | 2 | 1 | 1 | 4 | 105 | 42 | 63 | 60% | 9-14 | 4.61 | 1.49 |
| 2000-08-30 | Elmer Dessens | R | 29 | L 2-5 | @ ATL | 11 | 19 | L | 5.0 | 12 | 5 | 5 | 2 | 1 | 1 | 93 | 32 | 61 | 66% | 6-5 | 4.82 | 1.54 |
| 2000-08-31 | Pete Harnisch | R | 34 | W 4-3 | @ ATL | 18 | 307 | - | 2.2 | 1 | 2 | 2 | 1 | 2 | 2 | 34 | 14 | 20 | 59% | 6-6 | 4.67 | 1.42 |
| 2000-09-01 | Rob Bell | R | 24 | L 8-2 | vs MON | 22 | 22 | W | 8.0 | 6 | 2 | 2 | 0 | 3 | 4 | 113 | 50 | 63 | 56% | 6-7 | 4.76 | 1.48 |
| 2000-09-02 | Ron Villone | L | 31 | W 5-9 | vs MON | 20 | 42 | L | 5.2 | 7 | 6 | 6 | 0 | 5 | 0 | 80 | 37 | 43 | 54% | 9-8 | 5.58 | 1.70 |
| 2000-09-03 | Steve Parris | R | 33 | L 8-1 | vs MON | 28 | 84 | W | 7.0 | 9 | 1 | 1 | 0 | 2 | 4 | 109 | 37 | 72 | 66% | 10-14 | 4.47 | 1.49 |
| 2000-09-04 | Elmer Dessens | R | 29 | L 6-2 | vs NYN | 12 | 20 | W | 6.2 | 4 | 1 | 1 | 0 | 3 | 4 | 106 | 41 | 65 | 61% | 7-5 | 4.61 | 1.51 |
| 2000-09-05 | Pete Harnisch | R | 34 | W 2-3 | vs NYN | 19 | 308 | - | 7.0 | 4 | 2 | 2 | 0 | 1 | 3 | 84 | 27 | 57 | 68% | 6-6 | 4.54 | 1.37 |
| 2000-09-06 | Rob Bell | R | 24 | L 11-8 | vs NYN | 23 | 23 | - | 1.1 | 2 | 5 | 5 | 2 | 4 | 1 | 41 | 22 | 19 | 46% | 6-7 | 5.10 | 1.52 |
| 2000-09-08 | Scott Williamson | R | 25 | L 3-7 | @ PIT | 10 | 10 | L | 3.2 | 6 | 4 | 3 | 1 | 4 | 1 | 80 | 41 | 39 | 49% | 5-8 | 3.29 | 1.49 |
| 2000-09-08 | Ron Villone | L | 31 | L 1-3 | @ PIT | 21 | 43 | L | 5.2 | 5 | 3 | 3 | 0 | 2 | 2 | 97 | 37 | 60 | 62% | 9-9 | 5.53 | 1.68 |
| 2000-09-09 | Steve Parris | R | 33 | W 6-4 | @ PIT | 29 | 85 | W | 6.1 | 8 | 4 | 4 | 0 | 5 | 6 | 130 | 52 | 78 | 60% | 11-14 | 4.53 | 1.51 |
| 2000-09-10 | Elmer Dessens | R | 29 | W 6-4 | @ PIT | 13 | 21 | W | 7.0 | 6 | 4 | 3 | 0 | 4 | 2 | 97 | 39 | 58 | 60% | 8-5 | 4.57 | 1.51 |
| 2000-09-11 | Pete Harnisch | R | 34 | L 7-6 | vs CHN | 20 | 309 | W | 5.0 | 8 | 5 | 5 | 1 | 2 | 5 | 94 | 34 | 60 | 64% | 7-6 | 4.73 | 1.40 |
| 2000-09-12 | Osvaldo Fernandez | R | 32 | W 1-2 | vs CHN | 11 | 50 | L | 6.0 | 5 | 2 | 1 | 0 | 1 | 2 | 64 | 24 | 40 | 63% | 2-3 | 4.34 | 1.36 |
| 2000-09-13 | Rob Bell | R | 24 | L 13-3 | vs CHN | 24 | 24 | W | 9.0 | 6 | 3 | 3 | 1 | 3 | 6 | 109 | 40 | 69 | 63% | 7-7 | 4.95 | 1.48 |
| 2000-09-14 | Ron Villone | L | 31 | W 4-6 | vs MIL | 22 | 44 | L | 4.0 | 7 | 6 | 6 | 2 | 3 | 1 | 81 | 33 | 48 | 59% | 9-10 | 5.77 | 1.70 |
| 2000-09-15 | Steve Parris | R | 33 | L 6-4 | vs MIL | 30 | 86 | W | 6.0 | 5 | 2 | 2 | 1 | 4 | 6 | 115 | 47 | 68 | 59% | 12-14 | 4.47 | 1.51 |
| 2000-09-16 | Elmer Dessens | R | 29 | L 7-3 | vs MIL | 14 | 22 | W | 6.0 | 9 | 2 | 2 | 0 | 1 | 3 | 106 | 39 | 67 | 63% | 9-5 | 4.50 | 1.52 |
| 2000-09-17 | Pete Harnisch | R | 34 | L 8-4 | vs MIL | 21 | 310 | W | 7.0 | 5 | 4 | 3 | 3 | 0 | 6 | 94 | 30 | 64 | 68% | 8-6 | 4.68 | 1.36 |
| 2000-09-18 | Osvaldo Fernandez | R | 32 | W 7-1 | @ SFN | 12 | 51 | W | 9.0 | 4 | 1 | 1 | 0 | 1 | 2 | 113 | 42 | 71 | 63% | 3-3 | 3.90 | 1.25 |
| 2000-09-19 | Rob Bell | R | 24 | L 3-7 | @ SFN | 25 | 25 | L | 5.0 | 7 | 4 | 4 | 0 | 1 | 4 | 92 | 34 | 58 | 63% | 7-8 | 5.04 | 1.49 |
| 2000-09-20 | Steve Parris | R | 33 | L 2-4 | @ SFN | 31 | 87 | L | 5.0 | 5 | 4 | 4 | 1 | 3 | 2 | 83 | 34 | 49 | 59% | 12-15 | 4.55 | 1.52 |
| 2000-09-22 | Elmer Dessens | R | 29 | L 12-5 | vs HOU | 15 | 23 | W | 6.2 | 10 | 3 | 3 | 1 | 1 | 3 | 107 | 37 | 70 | 65% | 10-5 | 4.50 | 1.53 |
| 2000-09-23 | Pete Harnisch | R | 34 | L 6-4 | vs HOU | 22 | 311 | - | 6.0 | 8 | 4 | 4 | 2 | 1 | 5 | 86 | 23 | 63 | 73% | 8-6 | 4.74 | 1.37 |
| 2000-09-24 | Osvaldo Fernandez | R | 32 | L 4-3 | vs HOU | 13 | 52 | - | 5.2 | 6 | 3 | 3 | 0 | 4 | 2 | 87 | 39 | 48 | 55% | 3-3 | 3.95 | 1.29 |
| 2000-09-26 | Steve Parris | R | 33 | L 4-7 | @ MIL | 32 | 88 | L | 4.2 | 10 | 5 | 5 | 1 | 0 | 1 | 94 | 37 | 57 | 61% | 12-16 | 4.67 | 1.53 |
| 2000-09-27 | Rob Bell | R | 24 | L 6-10 | @ MIL | 26 | 26 | - | 6.0 | 4 | 3 | 3 | 3 | 0 | 6 | 76 | 23 | 53 | 70% | 7-8 | 5.01 | 1.45 |
| 2000-09-28 | Elmer Dessens | R | 29 | W 8-1 | @ MIL | 16 | 24 | W | 9.0 | 2 | 1 | 1 | 0 | 0 | 6 | 101 | 29 | 72 | 71% | 11-5 | 4.29 | 1.45 |
| 2000-09-29 | Ron Villone | L | 31 | W 8-1 | @ SLN | 23 | 45 | W | 9.0 | 2 | 1 | 0 | 0 | 5 | 16 | 151 | 61 | 90 | 60% | 10-10 | 5.43 | 1.65 |
| 2000-09-30 | Osvaldo Fernandez | R | 32 | W 8-4 | @ SLN | 14 | 53 | W | 7.0 | 4 | 0 | 0 | 0 | 2 | 5 | 98 | 32 | 66 | 67% | 4-3 | 3.60 | 1.25 |
| 2000-10-01 | Steve Parris | R | 33 | L 2-6 | @ SLN | 33 | 89 | L | 6.0 | 8 | 6 | 6 | 2 | 4 | 3 | 137 | 56 | 81 | 59% | 12-17 | 4.80 | 1.54 |