| West | W | L | Pct | GB |
| KC Royals | 97 | 65 | .599 | -- |
| Oakland | 83 | 79 | .512 | 14.0 |
| Minnesota | 77 | 84 | .478 | 19.5 |
| Texas | 76 | 85 | .472 | 20.5 |
| Chi White Sox | 70 | 90 | .437 | 26.0 |
| California | 65 | 95 | .406 | 31.0 |
| Seattle | 59 | 103 | .364 | 38.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 1980-04-10 | Jerry Koosman | L | 36 | W 9-7 | @ OAK | 1 | 383 | - | 6.2 | 7 | 4 | 4 | 0 | 1 | 4 | 0 | 0 | 0 | -- | 0-0 | 5.14 | 1.14 |
| 1980-04-11 | Pete Redfern | R | 26 | L 0-1 | @ OAK | 1 | 60 | L | 8.0 | 4 | 1 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | -- | 0-1 | 1.13 | 0.50 |
| 1980-04-12 | Geoff Zahn | L | 34 | W 6-0 | @ OAK | 1 | 115 | W | 9.0 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -- | 1-0 | 0.00 | 0.33 |
| 1980-04-13 | Roger Erickson | R | 24 | L 1-4 | @ OAK | 1 | 59 | L | 2.0 | 3 | 3 | 3 | 0 | 3 | 0 | 0 | 0 | 0 | -- | 0-1 | 13.50 | 3.00 |
| 1980-04-14 | Terry Felton | R | 22 | W 5-3 | @ CAL | 1 | 1 | - | 7.0 | 6 | 3 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | -- | 0-0 | 3.86 | 1.00 |
| 1980-04-15 | Jerry Koosman | L | 36 | L 1-3 | @ CAL | 2 | 384 | L | 4.1 | 7 | 3 | 2 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 0-1 | 4.91 | 1.45 |
| 1980-04-16 | Pete Redfern | R | 26 | L 1-2 | @ CAL | 2 | 61 | - | 8.0 | 6 | 1 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | -- | 0-1 | 1.13 | 0.63 |
| 1980-04-17 | Geoff Zahn | L | 34 | L 3-4 | @ SEA | 2 | 116 | L | 8.1 | 6 | 4 | 3 | 1 | 1 | 3 | 0 | 0 | 0 | -- | 1-1 | 1.59 | 0.59 |
| 1980-04-18 | Roger Erickson | R | 24 | L 1-3 | @ SEA | 2 | 60 | L | 8.0 | 6 | 3 | 2 | 0 | 1 | 4 | 0 | 0 | 0 | -- | 0-2 | 4.50 | 1.30 |
| 1980-04-18 | Terry Felton | R | 22 | L 2-3 | @ SEA | 2 | 2 | L | 5.1 | 5 | 3 | 3 | 0 | 1 | 7 | 0 | 0 | 0 | -- | 0-1 | 4.50 | 1.08 |
| 1980-04-19 | Jerry Koosman | L | 36 | W 8-3 | @ SEA | 3 | 385 | W | 8.1 | 7 | 3 | 3 | 1 | 2 | 4 | 0 | 0 | 0 | -- | 1-1 | 4.26 | 1.32 |
| 1980-04-20 | Pete Redfern | R | 26 | W 4-3 | @ SEA | 3 | 62 | W | 5.0 | 4 | 2 | 1 | 0 | 3 | 6 | 0 | 0 | 0 | -- | 1-1 | 1.29 | 0.81 |
| 1980-04-22 | Geoff Zahn | L | 34 | L 8-1 | vs CAL | 3 | 117 | W | 9.0 | 6 | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | -- | 2-1 | 1.38 | 0.62 |
| 1980-04-23 | Terry Felton | R | 22 | W 0-17 | vs CAL | 3 | 3 | L | 0.2 | 3 | 4 | 4 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 0-2 | 6.92 | 1.38 |
| 1980-04-25 | Jerry Koosman | L | 36 | L 10-3 | vs OAK | 4 | 386 | W | 7.2 | 7 | 2 | 2 | 2 | 3 | 5 | 0 | 0 | 0 | -- | 2-1 | 3.67 | 1.30 |
| 1980-04-26 | Pete Redfern | R | 26 | L 5-1 | vs OAK | 4 | 63 | W | 7.0 | 3 | 1 | 1 | 0 | 2 | 6 | 0 | 0 | 0 | -- | 2-1 | 1.29 | 0.79 |
| 1980-04-27 | Geoff Zahn | L | 34 | L 20-11 | vs OAK | 4 | 118 | - | 4.1 | 14 | 8 | 8 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 2-1 | 3.48 | 1.03 |
| 1980-04-28 | Terry Felton | R | 22 | W 4-6 | vs SEA | 4 | 4 | L | 3.2 | 3 | 5 | 1 | 0 | 4 | 2 | 0 | 0 | 0 | -- | 0-3 | 5.82 | 1.47 |
| 1980-04-29 | Jerry Koosman | L | 36 | W 3-5 | vs SEA | 5 | 387 | - | 7.0 | 5 | 2 | 2 | 1 | 1 | 3 | 0 | 0 | 0 | -- | 2-1 | 3.44 | 1.21 |
| 1980-04-30 | Pete Redfern | R | 26 | L 10-3 | vs SEA | 5 | 64 | W | 9.0 | 9 | 3 | 2 | 0 | 1 | 5 | 0 | 0 | 0 | -- | 3-1 | 1.46 | 0.86 |
| 1980-05-02 | Geoff Zahn | L | 34 | W 6-9 | vs NYA | 5 | 119 | L | 5.1 | 8 | 5 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 2-2 | 3.75 | 1.14 |
| 1980-05-03 | Darrell Jackson | L | 24 | W 3-7 | vs NYA | 1 | 24 | L | 5.1 | 7 | 4 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | -- | 0-1 | 2.81 | 1.19 |
| 1980-05-04 | Jerry Koosman | L | 36 | W 1-10 | vs NYA | 6 | 388 | L | 3.1 | 9 | 7 | 7 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 2-2 | 4.86 | 1.41 |
| 1980-05-05 | Pete Redfern | R | 26 | W 4-2 | @ BAL | 6 | 65 | W | 5.2 | 6 | 2 | 2 | 0 | 1 | 4 | 0 | 0 | 0 | -- | 4-1 | 1.67 | 0.91 |
| 1980-05-06 | Geoff Zahn | L | 34 | L 3-10 | @ BAL | 6 | 120 | L | 6.0 | 12 | 8 | 2 | 1 | 3 | 3 | 0 | 0 | 0 | -- | 2-3 | 3.64 | 1.33 |
| 1980-05-07 | Albert Williams | R | 26 | L 6-8 | @ BAL | 1 | 1 | - | 3.0 | 7 | 4 | 4 | 1 | 0 | 2 | 0 | 0 | 0 | -- | 0-0 | 12.00 | 2.33 |
| 1980-05-09 | Jerry Koosman | L | 36 | L 2-5 | @ NYA | 7 | 389 | L | 7.1 | 7 | 5 | 4 | 1 | 0 | 2 | 0 | 0 | 0 | -- | 2-3 | 4.80 | 1.31 |
| 1980-05-10 | Darrell Jackson | L | 24 | W 1-0 | @ NYA | 2 | 25 | W | 10.0 | 5 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 1-1 | 1.73 | 1.00 |
| 1980-05-11 | Geoff Zahn | L | 34 | L 0-5 | @ NYA | 7 | 121 | L | 6.2 | 7 | 5 | 5 | 0 | 3 | 3 | 0 | 0 | 0 | -- | 2-4 | 4.04 | 1.35 |
| 1980-05-12 | Pete Redfern | R | 26 | W 4-3 | @ BOS | 7 | 66 | W | 8.0 | 7 | 3 | 3 | 1 | 3 | 3 | 0 | 0 | 0 | -- | 5-1 | 1.94 | 0.96 |
| 1980-05-13 | Albert Williams | R | 26 | L 5-10 | @ BOS | 2 | 2 | - | 2.2 | 6 | 4 | 3 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 0-0 | 10.50 | 2.50 |
| 1980-05-14 | Jerry Koosman | L | 36 | L 6-7 | @ BOS | 8 | 390 | - | 5.1 | 8 | 6 | 6 | 1 | 0 | 7 | 0 | 0 | 0 | -- | 2-3 | 5.40 | 1.34 |
| 1980-05-16 | Darrell Jackson | L | 24 | L 4-3 | vs MIL | 3 | 26 | - | 1.0 | 5 | 3 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | -- | 1-1 | 2.67 | 1.15 |
| 1980-05-17 | Geoff Zahn | L | 34 | W 11-14 | vs MIL | 8 | 122 | L | 0.2 | 5 | 5 | 5 | 1 | 1 | 0 | 0 | 0 | 0 | -- | 2-5 | 4.96 | 1.47 |
| 1980-05-18 | Pete Redfern | R | 26 | L 10-4 | vs MIL | 8 | 67 | W | 7.0 | 8 | 4 | 3 | 1 | 2 | 5 | 0 | 0 | 0 | -- | 6-1 | 2.17 | 1.02 |
| 1980-05-19 | Jerry Koosman | L | 36 | L 0-1 | @ CHA | 9 | 391 | L | 8.0 | 3 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 3-4 | 4.73 | 1.24 |
| 1980-05-20 | Darrell Jackson | L | 24 | L 2-4 | @ CHA | 4 | 27 | L | 5.1 | 4 | 3 | 3 | 0 | 4 | 4 | 0 | 0 | 0 | -- | 1-2 | 3.09 | 1.26 |
| 1980-05-21 | Geoff Zahn | L | 34 | W 3-2 | @ CHA | 9 | 123 | W | 9.0 | 7 | 2 | 2 | 0 | 4 | 2 | 0 | 0 | 0 | -- | 3-5 | 4.50 | 1.43 |
| 1980-05-23 | Pete Redfern | R | 26 | L 0-5 | @ MIL | 9 | 68 | L | 3.2 | 5 | 5 | 5 | 2 | 2 | 5 | 0 | 0 | 0 | -- | 6-2 | 2.80 | 1.08 |
| 1980-05-24 | Jerry Koosman | L | 36 | L 0-4 | @ MIL | 10 | 392 | L | 6.1 | 8 | 4 | 4 | 1 | 1 | 4 | 0 | 0 | 0 | -- | 3-5 | 4.85 | 1.26 |
| 1980-05-25 | Roger Erickson | R | 24 | L 2-3 | @ MIL | 3 | 61 | L | 8.0 | 7 | 3 | 3 | 1 | 1 | 5 | 0 | 0 | 0 | -- | 0-3 | 2.73 | 1.21 |
| 1980-05-26 | Geoff Zahn | L | 34 | W 3-6 | vs CHA | 10 | 124 | L | 6.2 | 10 | 6 | 5 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 3-6 | 4.71 | 1.45 |
| 1980-05-27 | Darrell Jackson | L | 24 | W 0-2 | vs CHA | 5 | 28 | L | 7.0 | 5 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | -- | 1-3 | 3.00 | 1.19 |
| 1980-05-28 | Pete Redfern | R | 26 | L 6-4 | vs CHA | 10 | 69 | - | 5.2 | 7 | 4 | 4 | 1 | 0 | 3 | 0 | 0 | 0 | -- | 6-2 | 3.09 | 1.09 |
| 1980-05-29 | Jerry Koosman | L | 36 | L 5-2 | vs CHA | 11 | 393 | W | 9.0 | 5 | 2 | 2 | 0 | 4 | 5 | 0 | 0 | 0 | -- | 4-5 | 4.50 | 1.23 |
| 1980-05-30 | Roger Erickson | R | 24 | W 2-3 | vs BAL | 4 | 62 | - | 6.0 | 5 | 2 | 1 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 0-3 | 2.54 | 1.21 |
| 1980-05-31 | Geoff Zahn | L | 34 | W 1-11 | vs BAL | 11 | 125 | L | 3.0 | 10 | 7 | 5 | 1 | 1 | 4 | 0 | 0 | 0 | -- | 3-7 | 5.16 | 1.56 |
| 1980-06-02 | Pete Redfern | R | 26 | W 2-6 | vs BOS | 11 | 70 | L | 4.1 | 8 | 5 | 4 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 6-3 | 3.42 | 1.17 |
| 1980-06-03 | Jerry Koosman | L | 36 | L 9-4 | vs BOS | 12 | 394 | W | 9.0 | 5 | 4 | 1 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 5-5 | 4.12 | 1.18 |
| 1980-06-06 | Geoff Zahn | L | 34 | L 5-0 | vs TOR | 12 | 126 | W | 9.0 | 1 | 0 | 0 | 0 | 3 | 6 | 0 | 0 | 0 | -- | 4-7 | 4.50 | 1.43 |
| 1980-06-07 | Darrell Jackson | L | 24 | L 3-2 | vs TOR | 6 | 29 | W | 7.1 | 6 | 2 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | -- | 2-3 | 2.94 | 1.16 |
| 1980-06-08 | Roger Erickson | R | 24 | L 5-1 | vs TOR | 5 | 63 | W | 8.1 | 4 | 1 | 1 | 1 | 1 | 3 | 0 | 0 | 0 | -- | 1-3 | 2.30 | 1.11 |
| 1980-06-08 | Jerry Koosman | L | 36 | W 4-6 | vs TOR | 13 | 395 | - | 8.2 | 9 | 4 | 4 | 1 | 1 | 5 | 0 | 0 | 0 | -- | 5-5 | 4.11 | 1.17 |
| 1980-06-10 | Geoff Zahn | L | 34 | L 3-8 | @ DET | 13 | 127 | L | 2.1 | 5 | 5 | 5 | 0 | 1 | 1 | 0 | 0 | 0 | -- | 4-8 | 4.94 | 1.46 |
| 1980-06-11 | Darrell Jackson | L | 24 | W 9-5 | @ DET | 7 | 30 | W | 6.0 | 8 | 3 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | -- | 3-3 | 2.95 | 1.24 |
| 1980-06-12 | Pete Redfern | R | 26 | L 4-8 | @ DET | 12 | 71 | - | 3.2 | 6 | 4 | 4 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 6-3 | 3.72 | 1.21 |
| 1980-06-13 | Jerry Koosman | L | 36 | L 2-6 | @ CLE | 14 | 396 | L | 3.2 | 7 | 5 | 5 | 0 | 4 | 2 | 0 | 0 | 0 | -- | 5-6 | 4.41 | 1.24 |
| 1980-06-14 | Roger Erickson | R | 24 | L 2-3 | @ CLE | 6 | 64 | L | 6.1 | 8 | 3 | 2 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 1-4 | 2.33 | 1.17 |
| 1980-06-15 | Darrell Jackson | L | 24 | L 5-14 | @ CLE | 8 | 31 | L | 3.2 | 7 | 6 | 6 | 1 | 2 | 5 | 0 | 0 | 0 | -- | 3-4 | 3.66 | 1.31 |
| 1980-06-16 | Geoff Zahn | L | 34 | W 4-0 | @ TOR | 14 | 128 | W | 9.0 | 9 | 0 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | -- | 5-9 | 4.55 | 1.47 |
| 1980-06-17 | Pete Redfern | R | 26 | W 8-6 | @ TOR | 13 | 72 | - | 4.2 | 11 | 6 | 5 | 2 | 2 | 0 | 0 | 0 | 0 | -- | 6-3 | 4.05 | 1.30 |
| 1980-06-19 | Darrell Jackson | L | 24 | L 5-1 | vs DET | 9 | 32 | W | 7.2 | 6 | 0 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | -- | 4-4 | 3.27 | 1.29 |
| 1980-06-20 | Roger Erickson | R | 24 | W 3-4 | vs CLE | 7 | 65 | - | 5.2 | 7 | 3 | 3 | 1 | 3 | 1 | 0 | 0 | 0 | -- | 1-4 | 2.59 | 1.24 |
| 1980-06-21 | Geoff Zahn | L | 35 | L 3-2 | vs CLE | 15 | 129 | W | 8.1 | 10 | 2 | 2 | 0 | 0 | 5 | 0 | 0 | 0 | -- | 6-9 | 4.37 | 1.46 |
| 1980-06-22 | Pete Redfern | R | 26 | W 6-11 | vs CLE | 14 | 73 | L | 3.1 | 8 | 6 | 6 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 6-5 | 4.61 | 1.40 |
| 1980-06-23 | Jerry Koosman | L | 37 | L 4-1 | vs KCA | 15 | 397 | W | 9.0 | 10 | 1 | 1 | 0 | 2 | 15 | 0 | 0 | 0 | -- | 6-6 | 4.11 | 1.26 |
| 1980-06-24 | Darrell Jackson | L | 24 | L 2-1 | vs KCA | 10 | 33 | W | 9.0 | 5 | 1 | 1 | 0 | 2 | 7 | 0 | 0 | 0 | -- | 5-4 | 2.96 | 1.22 |
| 1980-06-24 | Roger Erickson | R | 24 | W 2-4 | vs KCA | 8 | 66 | L | 5.0 | 11 | 3 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | -- | 1-5 | 2.81 | 1.31 |
| 1980-06-25 | Geoff Zahn | L | 35 | W 1-4 | vs KCA | 16 | 130 | L | 9.0 | 10 | 4 | 4 | 1 | 1 | 5 | 0 | 0 | 0 | -- | 6-10 | 4.34 | 1.44 |
| 1980-06-27 | Pete Redfern | R | 26 | L 0-5 | @ TEX | 15 | 74 | L | 1.0 | 5 | 4 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | -- | 6-6 | 4.91 | 1.42 |
| 1980-06-28 | Jerry Koosman | L | 37 | L 3-11 | @ TEX | 16 | 398 | L | 2.0 | 7 | 5 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | -- | 6-7 | 4.46 | 1.30 |
| 1980-06-29 | Roger Erickson | R | 24 | W 5-3 | @ TEX | 9 | 67 | W | 6.0 | 7 | 2 | 2 | 1 | 2 | 4 | 0 | 0 | 0 | -- | 2-5 | 2.83 | 1.33 |
| 1980-06-30 | Darrell Jackson | L | 24 | W 12-3 | @ KCA | 11 | 34 | W | 7.0 | 4 | 3 | 3 | 1 | 6 | 7 | 0 | 0 | 0 | -- | 6-4 | 3.04 | 1.24 |
| 1980-07-01 | Geoff Zahn | L | 35 | W 2-1 | @ KCA | 17 | 131 | - | 7.1 | 8 | 1 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 6-10 | 4.12 | 1.42 |
| 1980-07-02 | Jerry Koosman | L | 37 | L 3-4 | @ KCA | 17 | 399 | L | 9.1 | 10 | 4 | 4 | 0 | 2 | 5 | 0 | 0 | 0 | -- | 6-8 | 4.42 | 1.30 |
| 1980-07-03 | Roger Erickson | R | 24 | L 10-3 | vs TEX | 10 | 68 | W | 6.0 | 8 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 3-5 | 2.96 | 1.34 |
| 1980-07-04 | Darrell Jackson | L | 24 | W 3-4 | vs TEX | 12 | 35 | - | 7.0 | 5 | 3 | 3 | 2 | 4 | 4 | 0 | 0 | 0 | -- | 6-4 | 3.10 | 1.24 |
| 1980-07-05 | Geoff Zahn | L | 35 | L 2-1 | vs TEX | 18 | 132 | W | 9.0 | 6 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 7-10 | 3.90 | 1.38 |
| 1980-07-06 | Fernando Arroyo | R | 28 | L 4-1 | vs TEX | 1 | 31 | W | 7.2 | 3 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | -- | 1-1 | 3.86 | 1.14 |
| 1980-07-10 | Jerry Koosman | L | 37 | W 12-4 | @ SEA | 18 | 400 | W | 9.0 | 8 | 4 | 4 | 0 | 0 | 8 | 0 | 0 | 0 | -- | 7-8 | 4.32 | 1.26 |
| 1980-07-11 | Darrell Jackson | L | 24 | W 6-3 | @ SEA | 13 | 36 | W | 7.2 | 6 | 3 | 3 | 1 | 2 | 8 | 0 | 0 | 0 | -- | 7-4 | 3.15 | 1.24 |
| 1980-07-12 | Geoff Zahn | L | 35 | L 8-3 | vs SEA | 19 | 133 | W | 8.0 | 8 | 3 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | -- | 8-10 | 3.87 | 1.37 |
| 1980-07-13 | Roger Erickson | R | 24 | L 7-6 | vs SEA | 11 | 69 | - | 5.0 | 6 | 4 | 4 | 0 | 2 | 5 | 0 | 0 | 0 | -- | 3-5 | 3.22 | 1.36 |
| 1980-07-14 | Fernando Arroyo | R | 28 | W 5-8 | vs SEA | 2 | 32 | L | 4.1 | 5 | 6 | 4 | 1 | 3 | 0 | 0 | 0 | 0 | -- | 1-2 | 4.68 | 1.28 |
| 1980-07-15 | Jerry Koosman | L | 37 | W 5-4 | @ NYA | 19 | 401 | W | 8.0 | 9 | 4 | 4 | 2 | 2 | 6 | 0 | 0 | 0 | -- | 8-8 | 4.33 | 1.27 |
| 1980-07-16 | Darrell Jackson | L | 24 | L 1-11 | @ NYA | 14 | 37 | L | 3.0 | 7 | 7 | 7 | 0 | 3 | 0 | 0 | 0 | 0 | -- | 7-5 | 3.69 | 1.30 |
| 1980-07-17 | Geoff Zahn | L | 35 | L 3-10 | @ NYA | 20 | 134 | L | 4.0 | 7 | 6 | 6 | 2 | 2 | 3 | 0 | 0 | 0 | -- | 8-11 | 4.14 | 1.40 |
| 1980-07-18 | Roger Erickson | R | 24 | L 0-1 | @ BOS | 12 | 70 | L | 9.1 | 8 | 1 | 1 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 3-6 | 2.97 | 1.32 |
| 1980-07-19 | Fernando Arroyo | R | 28 | W 4-0 | @ BOS | 3 | 33 | W | 9.0 | 5 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 2-2 | 3.44 | 1.15 |
| 1980-07-20 | Jerry Koosman | L | 37 | W 5-4 | @ BOS | 20 | 402 | - | 3.0 | 7 | 4 | 4 | 0 | 1 | 1 | 0 | 0 | 0 | -- | 8-8 | 4.50 | 1.30 |
| 1980-07-21 | Darrell Jackson | L | 24 | L 8-7 | vs BAL | 15 | 38 | - | 2.1 | 8 | 5 | 5 | 0 | 3 | 1 | 0 | 0 | 0 | -- | 7-5 | 4.02 | 1.37 |
| 1980-07-21 | Geoff Zahn | L | 35 | W 5-12 | vs BAL | 21 | 135 | L | 5.2 | 11 | 10 | 10 | 3 | 5 | 2 | 0 | 0 | 0 | -- | 8-12 | 4.63 | 1.46 |
| 1980-07-22 | Roger Erickson | R | 24 | W 4-8 | vs BAL | 13 | 71 | L | 4.2 | 8 | 7 | 7 | 1 | 2 | 4 | 0 | 0 | 0 | -- | 3-7 | 3.51 | 1.37 |
| 1980-07-23 | Fernando Arroyo | R | 28 | W 7-8 | vs BAL | 4 | 34 | L | 6.1 | 8 | 7 | 7 | 0 | 7 | 6 | 0 | 0 | 0 | -- | 2-3 | 4.39 | 1.32 |
| 1980-07-25 | Jerry Koosman | L | 37 | W 5-7 | vs BOS | 21 | 403 | L | 5.0 | 8 | 6 | 6 | 2 | 2 | 0 | 0 | 0 | 0 | -- | 8-9 | 4.72 | 1.32 |
| 1980-07-25 | Geoff Zahn | L | 35 | L 6-0 | vs BOS | 22 | 136 | W | 9.0 | 9 | 0 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | -- | 9-12 | 4.35 | 1.44 |
| 1980-07-26 | Roger Erickson | R | 24 | W 1-5 | vs BOS | 14 | 72 | L | 8.0 | 11 | 5 | 5 | 1 | 3 | 2 | 0 | 0 | 0 | -- | 3-8 | 3.67 | 1.40 |
| 1980-07-27 | Fernando Arroyo | R | 28 | L 5-4 | vs BOS | 5 | 35 | - | 1.2 | 6 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | -- | 2-3 | 4.93 | 1.43 |
| 1980-07-28 | Darrell Jackson | L | 24 | W 6-7 | vs NYA | 16 | 39 | - | 7.1 | 8 | 4 | 3 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 7-5 | 3.98 | 1.37 |
| 1980-07-29 | Geoff Zahn | L | 35 | L 3-2 | vs NYA | 23 | 137 | W | 9.0 | 10 | 2 | 2 | 0 | 0 | 3 | 0 | 0 | 0 | -- | 10-12 | 4.22 | 1.42 |
| 1980-07-30 | Jerry Koosman | L | 37 | L 2-1 | vs NYA | 22 | 404 | W | 10.0 | 3 | 1 | 1 | 0 | 5 | 4 | 0 | 0 | 0 | -- | 9-9 | 4.47 | 1.29 |
| 1980-08-01 | Roger Erickson | R | 24 | L 2-3 | @ BAL | 15 | 73 | - | 7.0 | 8 | 2 | 1 | 0 | 3 | 3 | 0 | 0 | 0 | -- | 3-8 | 3.52 | 1.41 |
| 1980-08-02 | Fernando Arroyo | R | 28 | L 2-9 | @ BAL | 6 | 36 | L | 4.0 | 5 | 5 | 5 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 2-4 | 5.48 | 1.48 |
| 1980-08-03 | Darrell Jackson | L | 24 | L 2-7 | @ BAL | 17 | 40 | L | 4.1 | 6 | 5 | 3 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 7-6 | 4.08 | 1.39 |
| 1980-08-04 | Geoff Zahn | L | 35 | L 2-11 | @ OAK | 24 | 138 | L | 0.2 | 6 | 8 | 8 | 1 | 2 | 0 | 0 | 0 | 0 | -- | 10-13 | 4.64 | 1.46 |
| 1980-08-05 | Jerry Koosman | L | 37 | L 2-3 | @ OAK | 23 | 405 | L | 6.2 | 8 | 3 | 3 | 0 | 4 | 3 | 0 | 0 | 0 | -- | 9-10 | 4.47 | 1.31 |
| 1980-08-06 | Roger Erickson | R | 24 | L 1-3 | @ OAK | 16 | 74 | L | 6.1 | 6 | 3 | 3 | 0 | 3 | 4 | 0 | 0 | 0 | -- | 3-9 | 3.54 | 1.40 |
| 1980-08-07 | Fernando Arroyo | R | 28 | L 2-4 | @ CAL | 7 | 37 | - | 7.1 | 5 | 2 | 2 | 0 | 3 | 1 | 0 | 0 | 0 | -- | 2-4 | 5.00 | 1.41 |
| 1980-08-08 | Darrell Jackson | L | 24 | L 5-9 | @ CAL | 18 | 41 | L | 4.0 | 7 | 5 | 5 | 1 | 1 | 3 | 0 | 0 | 0 | -- | 7-7 | 4.31 | 1.41 |
| 1980-08-09 | Geoff Zahn | L | 35 | L 2-8 | @ CAL | 25 | 139 | L | 6.2 | 8 | 5 | 5 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 10-14 | 4.71 | 1.46 |
| 1980-08-10 | Jerry Koosman | L | 37 | W 5-2 | @ CAL | 24 | 406 | W | 7.2 | 9 | 2 | 1 | 1 | 1 | 6 | 0 | 0 | 0 | -- | 10-10 | 4.31 | 1.31 |
| 1980-08-12 | Roger Erickson | R | 24 | L 3-2 | vs OAK | 17 | 75 | - | 8.1 | 9 | 2 | 2 | 1 | 1 | 4 | 0 | 0 | 0 | -- | 3-9 | 3.46 | 1.39 |
| 1980-08-13 | Fernando Arroyo | R | 28 | W 2-6 | vs OAK | 8 | 38 | L | 5.1 | 6 | 4 | 4 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 2-5 | 5.19 | 1.42 |
| 1980-08-14 | Darrell Jackson | L | 24 | W 1-2 | vs OAK | 19 | 42 | - | 10.0 | 6 | 1 | 1 | 0 | 3 | 4 | 0 | 0 | 0 | -- | 7-7 | 4.05 | 1.37 |
| 1980-08-15 | Geoff Zahn | L | 35 | W 4-5 | vs CAL | 26 | 140 | L | 8.0 | 11 | 5 | 5 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 10-15 | 4.75 | 1.46 |
| 1980-08-17 | Roger Erickson | R | 24 | L 8-1 | vs CAL | 18 | 76 | W | 9.0 | 6 | 1 | 1 | 0 | 4 | 7 | 0 | 0 | 0 | -- | 4-9 | 3.29 | 1.37 |
| 1980-08-17 | Jerry Koosman | L | 37 | L 6-5 | vs CAL | 25 | 407 | W | 7.1 | 9 | 5 | 5 | 2 | 2 | 5 | 0 | 0 | 0 | -- | 11-10 | 4.40 | 1.32 |
| 1980-08-18 | Fernando Arroyo | R | 28 | L 8-3 | vs CAL | 9 | 39 | W | 8.2 | 8 | 3 | 3 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 3-5 | 4.90 | 1.38 |
| 1980-08-19 | Darrell Jackson | L | 24 | W 3-4 | vs TOR | 20 | 43 | - | 7.0 | 6 | 3 | 2 | 0 | 4 | 3 | 0 | 0 | 0 | -- | 7-7 | 3.98 | 1.38 |
| 1980-08-20 | Geoff Zahn | L | 35 | W 4-10 | vs TOR | 27 | 141 | L | 7.0 | 6 | 5 | 3 | 0 | 3 | 4 | 0 | 0 | 0 | -- | 10-16 | 4.72 | 1.45 |
| 1980-08-21 | Albert Williams | R | 26 | L 5-3 | vs DET | 3 | 3 | W | 7.0 | 7 | 3 | 3 | 0 | 4 | 6 | 0 | 0 | 0 | -- | 2-1 | 4.67 | 1.52 |
| 1980-08-21 | Roger Erickson | R | 24 | W 2-4 | vs DET | 19 | 77 | L | 7.0 | 11 | 4 | 3 | 2 | 1 | 2 | 0 | 0 | 0 | -- | 4-10 | 3.32 | 1.39 |
| 1980-08-22 | Jerry Koosman | L | 37 | L 6-5 | vs DET | 26 | 408 | - | 7.2 | 11 | 5 | 5 | 1 | 0 | 6 | 0 | 0 | 0 | -- | 11-10 | 4.45 | 1.32 |
| 1980-08-23 | Darrell Jackson | L | 24 | W 3-4 | vs DET | 21 | 44 | L | 7.0 | 8 | 3 | 4 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 7-8 | 4.03 | 1.39 |
| 1980-08-24 | Geoff Zahn | L | 35 | W 2-3 | vs DET | 28 | 142 | L | 9.0 | 7 | 3 | 3 | 1 | 7 | 4 | 0 | 0 | 0 | -- | 10-17 | 4.64 | 1.46 |
| 1980-08-25 | Fernando Arroyo | R | 28 | L 3-4 | @ CLE | 10 | 40 | L | 5.0 | 6 | 4 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | -- | 4-6 | 4.86 | 1.37 |
| 1980-08-26 | Roger Erickson | R | 24 | W 5-1 | @ CLE | 20 | 78 | W | 8.0 | 7 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 5-10 | 3.20 | 1.38 |
| 1980-08-27 | Jerry Koosman | L | 37 | L 1-4 | @ CLE | 27 | 409 | L | 6.1 | 11 | 4 | 4 | 0 | 3 | 4 | 0 | 0 | 0 | -- | 11-11 | 4.50 | 1.36 |
| 1980-08-28 | Darrell Jackson | L | 24 | W 7-5 | @ TOR | 22 | 45 | - | 7.0 | 8 | 4 | 4 | 1 | 2 | 5 | 0 | 0 | 0 | -- | 7-8 | 4.09 | 1.39 |
| 1980-08-29 | Geoff Zahn | L | 35 | W 5-2 | @ TOR | 29 | 143 | W | 9.0 | 9 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | -- | 11-17 | 4.52 | 1.44 |
| 1980-08-30 | Roger Erickson | R | 24 | L 2-3 | @ TOR | 21 | 79 | - | 8.1 | 7 | 2 | 2 | 1 | 0 | 5 | 0 | 0 | 0 | -- | 5-10 | 3.15 | 1.35 |
| 1980-08-31 | Jerry Koosman | L | 37 | L 1-7 | @ TOR | 28 | 410 | L | 5.2 | 9 | 7 | 4 | 1 | 1 | 5 | 0 | 0 | 0 | -- | 11-12 | 4.55 | 1.37 |
| 1980-09-01 | Albert Williams | R | 26 | W 2-5 | vs CLE | 4 | 4 | L | 8.1 | 7 | 5 | 5 | 2 | 7 | 4 | 0 | 0 | 0 | -- | 2-2 | 4.17 | 1.54 |
| 1980-09-02 | Darrell Jackson | L | 24 | L 5-3 | vs CLE | 23 | 46 | W | 7.2 | 6 | 3 | 3 | 0 | 1 | 6 | 0 | 0 | 0 | -- | 8-8 | 4.05 | 1.37 |
| 1980-09-03 | Geoff Zahn | L | 35 | W 1-7 | vs CLE | 30 | 144 | L | 0.2 | 4 | 5 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | -- | 11-18 | 4.61 | 1.46 |
| 1980-09-05 | Roger Erickson | R | 24 | L 0-1 | @ DET | 22 | 80 | L | 8.0 | 5 | 1 | 1 | 0 | 1 | 5 | 0 | 0 | 0 | -- | 5-11 | 3.05 | 1.32 |
| 1980-09-06 | Jerry Koosman | L | 37 | W 4-0 | @ DET | 29 | 411 | W | 8.1 | 3 | 0 | 0 | 0 | 5 | 3 | 0 | 0 | 0 | -- | 12-12 | 4.37 | 1.35 |
| 1980-09-07 | Darrell Jackson | L | 24 | W 3-1 | @ DET | 24 | 47 | W | 7.0 | 4 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 9-8 | 3.88 | 1.35 |
| 1980-09-09 | Albert Williams | R | 26 | L 15-2 | vs MIL | 5 | 5 | W | 9.0 | 6 | 2 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 3-2 | 3.78 | 1.42 |
| 1980-09-10 | Roger Erickson | R | 24 | W 1-3 | vs MIL | 23 | 81 | L | 9.0 | 7 | 3 | 3 | 1 | 0 | 5 | 0 | 0 | 0 | -- | 5-12 | 3.05 | 1.29 |
| 1980-09-12 | Jerry Koosman | L | 37 | L 3-5 | @ CHA | 30 | 412 | L | 7.0 | 7 | 4 | 4 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 12-13 | 4.39 | 1.35 |
| 1980-09-13 | Geoff Zahn | L | 35 | W 6-5 | @ CHA | 31 | 145 | W | 7.0 | 8 | 3 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 12-18 | 4.59 | 1.46 |
| 1980-09-14 | Albert Williams | R | 26 | W 3-2 | @ CHA | 6 | 6 | - | 1.1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -- | 3-2 | 3.71 | 1.41 |
| 1980-09-17 | Jerry Koosman | L | 37 | W 3-2 | @ MIL | 31 | 413 | W | 9.0 | 8 | 2 | 2 | 0 | 2 | 8 | 0 | 0 | 0 | -- | 13-13 | 4.29 | 1.34 |
| 1980-09-17 | Roger Erickson | R | 24 | W 6-1 | @ MIL | 24 | 82 | W | 9.0 | 5 | 1 | 1 | 0 | 1 | 6 | 0 | 0 | 0 | -- | 6-12 | 2.95 | 1.26 |
| 1980-09-18 | Geoff Zahn | L | 35 | L 8-9 | @ MIL | 32 | 146 | - | 1.2 | 5 | 7 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | -- | 12-18 | 4.54 | 1.47 |
| 1980-09-18 | Pete Redfern | R | 26 | L 0-5 | @ MIL | 16 | 75 | L | 3.0 | 5 | 3 | 3 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 6-7 | 4.94 | 1.42 |
| 1980-09-19 | Albert Williams | R | 26 | L 6-3 | vs CHA | 7 | 7 | W | 8.0 | 9 | 3 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | -- | 4-2 | 3.66 | 1.39 |
| 1980-09-21 | Geoff Zahn | L | 35 | L 5-4 | vs CHA | 33 | 147 | - | 5.1 | 7 | 4 | 4 | 0 | 2 | 4 | 0 | 0 | 0 | -- | 12-18 | 4.60 | 1.48 |
| 1980-09-21 | Fernando Arroyo | R | 29 | L 6-4 | vs CHA | 11 | 41 | W | 6.1 | 8 | 4 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 6-6 | 4.30 | 1.36 |
| 1980-09-22 | Jerry Koosman | L | 37 | L 1-0 | vs TEX | 32 | 414 | W | 8.0 | 9 | 0 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | -- | 14-13 | 4.14 | 1.35 |
| 1980-09-23 | Roger Erickson | R | 24 | L 8-2 | vs TEX | 25 | 83 | W | 5.0 | 8 | 2 | 2 | 0 | 4 | 2 | 0 | 0 | 0 | -- | 7-12 | 2.97 | 1.29 |
| 1980-09-24 | Albert Williams | R | 26 | L 9-5 | vs TEX | 8 | 8 | W | 9.0 | 8 | 5 | 5 | 2 | 2 | 3 | 0 | 0 | 0 | -- | 5-2 | 3.84 | 1.35 |
| 1980-09-26 | Geoff Zahn | L | 35 | L 3-0 | vs KCA | 34 | 148 | W | 9.0 | 6 | 0 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | -- | 13-18 | 4.42 | 1.45 |
| 1980-09-27 | Jerry Koosman | L | 37 | L 8-3 | vs KCA | 33 | 415 | W | 9.0 | 3 | 3 | 2 | 1 | 4 | 5 | 0 | 0 | 0 | -- | 15-13 | 4.06 | 1.32 |
| 1980-09-28 | Roger Erickson | R | 24 | L 8-7 | vs KCA | 26 | 84 | - | 2.2 | 5 | 3 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | -- | 7-12 | 3.02 | 1.30 |
| 1980-10-02 | Geoff Zahn | L | 35 | W 6-3 | @ TEX | 35 | 149 | W | 6.1 | 8 | 3 | 3 | 0 | 3 | 3 | 0 | 0 | 0 | -- | 14-18 | 4.40 | 1.45 |
| 1980-10-02 | Albert Williams | R | 26 | W 4-1 | @ TEX | 9 | 9 | W | 9.0 | 9 | 1 | 1 | 1 | 2 | 4 | 0 | 0 | 0 | -- | 6-2 | 3.51 | 1.34 |
| 1980-10-03 | Jerry Koosman | L | 37 | W 5-3 | @ KCA | 34 | 416 | W | 8.0 | 8 | 3 | 3 | 1 | 2 | 4 | 0 | 0 | 0 | -- | 16-13 | 4.04 | 1.32 |
| 1980-10-04 | Roger Erickson | R | 24 | L 1-17 | @ KCA | 27 | 85 | L | 0.1 | 4 | 5 | 5 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 7-13 | 3.25 | 1.33 |
| 1980-10-05 | Darrell Jackson | L | 25 | L 0-4 | @ KCA | 25 | 48 | L | 5.0 | 2 | 3 | 2 | 1 | 3 | 2 | 0 | 0 | 0 | -- | 9-9 | 3.87 | 1.34 |