| - | Oscar Baldwin | | A+ | | | | | | - | | 1979 | UDFA | | BOS |
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| - | Lloyd Bessard | OF | A+ | | | | | | - | | 1978 | 14 | 362 | BOS |
| - | Bob Birrell | P | AAA | 6-0 | 175 | Right | Left | 10/8/1957 | 22 | Warwick,Rhode Island | 1979 | 19 | 494 | BOS |
| - | Mike Brown | P | MLB | 6-2 | 195 | Right | Right | 3/4/1959 | 21 | Camden,New Jersey | 1980 | 2 | 48 | BOS |
| - | Thomas Brummer | C | A+ | 6-0 | 175 | Left | Right | 3/6/1958 | 22 | Olney,Illinois | 1979 | UDFA | | BOS |
| - | Juan Bustabad | SS | AAA | 5-10 | 150 | Left | Right | 8/16/1961 | 18 | Havana,Cuba | 1980 | 1 | 1 | BOS |
| - | Stephen Collins | P | A+ | 6-2 | 200 | Right | Right | 4/24/1956 | 24 | San Francisco,California | 1977 | 1 | 7 | BOS |
| - | Gordon Davis | | A+ | | | | | | - | | 1980 | UDFA | | BOS |
| - | William Davis | P | A+ | 6-3 | 200 | Right | Right | 1/16/1959 | 21 | Pawnee,Oklahoma | 1981 | UDFA | | DET |
| - | Thomas DeSanto | P | A+ | 6-1 | 180 | Right | Right | 11/12/1958 | 21 | Elmira,New York | 1979 | UDFA | | BOS |
| - | Pat Dodson | 1B | MLB | 6-4 | 210 | Left | Left | 10/11/1959 | 20 | Santa Monica,California | 1980 | 6 | 154 | BOS |
| - | Matthew Gaglione | OF | A+ | | | | | | - | | 1976 | 6 | 112 | MTL |
| - | Frank Gill | | A+ | | | | | | - | | 1978 | UDFA | | BOS |
| - | Kevin Grubbs | P | A+ | 6-3 | 172 | Right | Right | 6/13/1961 | 19 | Napa,California | 1980 | UDFA | | BOS |
| - | Jackie Gutierrez | SS | MLB | 5-11 | 175 | Right | Right | 6/27/1960 | 20 | Cartagena,Colombia | 1978 | UDFA | | BOS |
| - | Ken Hagemann | 1B | A+ | | | | | | - | | 1978 | 7 | 180 | BOS |
| - | Donald Hayford | P | A+ | 6-1 | 170 | Right | Right | 11/5/1960 | 19 | Lakeland,Florida | 1978 | 10 | 258 | BOS |
| - | Dave Holt | C-1B | AA | 5-10 | 175 | Left | Right | 1/13/1958 | 22 | Fresno,California | 1979 | 21 | 545 | BOS |
| - | Clint Johnson | P | AA | 6-2 | 175 | Left | Right | 4/16/1956 | 24 | Canton,Mississippi | 1978 | UDFA | | BOS |
| - | Gus Malespin | IF | A+ | 5-9 | 178 | Right | Right | 12/4/1958 | 21 | Managua,Nicaragua | 1979 | UDFA | | BOS |
| - | Jeffrey Martin | | A+ | | | | | | - | | 1980 | UDFA | | BOS |
| - | Jerry Miklosi | SS | A+ | | | | | | - | | 1979 | 10 | 260 | BOS |
| - | Bill Moloney | P | AAA | 5-11 | 200 | Left | Left | 3/21/1956 | 24 | Lowell,Massachusetts | 1979 | UDFA | | BOS |
| - | John Morgan | 3B | AA | 6-2 | 188 | Right | Right | 2/19/1956 | 24 | Boston,Massachusetts | 1977 | 3 | 65 | BOS |
| - | Al Nipper | P | MLB | 6-0 | 194 | Right | Right | 4/2/1959 | 21 | San Diego,California | 1980 | 8 | 206 | BOS |
| - | Chuck Sandberg | 1B | AA | 6-3 | 194 | Left | Left | 3/15/1958 | 22 | Winter Park,Florida | 1979 | 9 | 234 | BOS |
| - | Steven Schneck | P | AAA | 6-1 | 180 | Right | Right | 2/14/1956 | 24 | | 1976 | 3 | 69 | BOS |
| - | Marc Sullivan | C | MLB | 6-4 | 205 | Right | Right | 7/25/1958 | 21 | Quincy,Massachusetts | 1979 | 2 | 52 | BOS |
| - | Jim Watkins | OF | AA | 6-0 | 175 | Left | Right | 10/7/1957 | 22 | Gary,Indiana | 1979 | 5 | 130 | BOS |
| - | Jackie Wright | 3B | AA | 5-11 | 160 | Right | Right | 9/13/1959 | 20 | | 1978 | UDFA | | BOS |