| Teams | W | L | Pct | GB |
| NY Yankees | 98 | 56 | .636 | -- |
| Detroit | 95 | 59 | .617 | 3.0 |
| Boston | 94 | 60 | .610 | 4.0 |
| Cleveland | 92 | 62 | .597 | 6.0 |
| Washington | 67 | 87 | .435 | 31.0 |
| Chi White Sox | 60 | 94 | .390 | 38.0 |
| St. Louis | 58 | 96 | .377 | 40.0 |
| Philadelphia | 52 | 102 | .338 | 46.0 |
| Date | Pitcher | Hand | Age | Game Result | Opp | GS# | Career | Dec | IP | H | R | ER | HR | BB | SO | Pit | Bal | Str | Str% | W-L | ERA | WHIP |
| 1950-04-18 | Fred Hutchinson | R | 31 | W 7-6 | @ CLE | 1 | 1 | - | 7.0 | 13 | 6 | 6 | 2 | 1 | 3 | 0 | 0 | 0 | -- | 0-0 | 7.71 | 2.00 |
| 1950-04-20 | Ted Gray | L | 25 | W 5-4 | @ CLE | 1 | 1 | W | 9.0 | 6 | 4 | 4 | 1 | 2 | 6 | 0 | 0 | 0 | -- | 1-0 | 4.00 | 0.89 |
| 1950-04-21 | Virgil Trucks | R | 33 | L 4-1 | vs CHA | 1 | 1 | W | 9.0 | 5 | 1 | 1 | 0 | 3 | 5 | 0 | 0 | 0 | -- | 1-0 | 1.00 | 0.89 |
| 1950-04-22 | Art Houtteman | R | 23 | L 5-0 | vs CHA | 1 | 1 | W | 9.0 | 4 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 2-0 | 0.00 | 0.82 |
| 1950-04-23 | Fred Hutchinson | R | 31 | W 4-5 | vs CHA | 2 | 2 | L | 5.2 | 7 | 5 | 2 | 0 | 3 | 3 | 0 | 0 | 0 | -- | 0-1 | 5.54 | 1.85 |
| 1950-04-28 | Ted Gray | L | 25 | W 1-6 | vs CLE | 2 | 2 | L | 7.0 | 3 | 3 | 2 | 0 | 4 | 3 | 0 | 0 | 0 | -- | 1-1 | 3.38 | 0.94 |
| 1950-04-30 | Art Houtteman | R | 23 | L 0-5 | @ CHA | 2 | 2 | L | 7.0 | 7 | 2 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 2-1 | 1.00 | 0.94 |
| 1950-05-04 | Art Houtteman | R | 23 | W 8-5 | @ PHA | 3 | 3 | W | 9.0 | 5 | 5 | 5 | 1 | 4 | 3 | 0 | 0 | 0 | -- | 3-1 | 2.33 | 0.96 |
| 1950-05-05 | Virgil Trucks | R | 33 | W 9-6 | @ WS1 | 2 | 2 | - | 4.2 | 8 | 5 | 5 | 1 | 4 | 1 | 0 | 0 | 0 | -- | 1-0 | 3.86 | 1.43 |
| 1950-05-06 | Fred Hutchinson | R | 31 | W 8-6 | @ WS1 | 3 | 3 | W | 8.2 | 11 | 5 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | -- | 1-1 | 4.71 | 1.67 |
| 1950-05-07 | Ted Gray | L | 25 | L 3-6 | @ NYA | 3 | 3 | - | 5.1 | 7 | 3 | 3 | 1 | 4 | 4 | 0 | 0 | 0 | -- | 1-1 | 3.86 | 1.24 |
| 1950-05-08 | Art Houtteman | R | 23 | W 7-1 | @ NYA | 4 | 4 | W | 9.0 | 8 | 1 | 1 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 4-1 | 2.00 | 1.03 |
| 1950-05-09 | Virgil Trucks | R | 33 | L 1-6 | @ BOS | 3 | 3 | L | 5.2 | 8 | 5 | 5 | 2 | 0 | 3 | 0 | 0 | 0 | -- | 1-1 | 5.21 | 1.47 |
| 1950-05-11 | Fred Hutchinson | R | 31 | W 13-4 | @ BOS | 4 | 4 | W | 9.0 | 7 | 4 | 4 | 1 | 5 | 2 | 0 | 0 | 0 | -- | 2-1 | 4.50 | 1.57 |
| 1950-05-11 | Ted Gray | L | 25 | W 5-3 | @ BOS | 4 | 4 | W | 7.0 | 6 | 2 | 2 | 1 | 2 | 7 | 0 | 0 | 0 | -- | 2-1 | 3.54 | 1.21 |
| 1950-05-13 | Virgil Trucks | R | 33 | L 1-0 | vs SLA | 4 | 4 | W | 11.0 | 5 | 0 | 0 | 0 | 5 | 8 | 0 | 0 | 0 | -- | 2-1 | 3.30 | 1.27 |
| 1950-05-16 | Art Houtteman | R | 23 | W 1-6 | vs BOS | 5 | 5 | L | 7.0 | 8 | 4 | 4 | 3 | 2 | 5 | 0 | 0 | 0 | -- | 4-2 | 2.60 | 1.13 |
| 1950-05-17 | Ted Gray | L | 25 | L 6-3 | vs BOS | 5 | 5 | W | 9.0 | 9 | 3 | 3 | 2 | 2 | 4 | 0 | 0 | 0 | -- | 3-1 | 3.41 | 1.22 |
| 1950-05-18 | Fred Hutchinson | R | 31 | W 12-13 | vs BOS | 5 | 5 | L | 3.0 | 6 | 7 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | -- | 2-2 | 6.00 | 1.67 |
| 1950-05-19 | Virgil Trucks | R | 33 | L 14-8 | vs PHA | 5 | 5 | - | 2.2 | 4 | 3 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | -- | 2-1 | 3.55 | 1.30 |
| 1950-05-21 | Ted Gray | L | 25 | W 2-6 | vs WS1 | 6 | 6 | L | 4.0 | 8 | 6 | 5 | 2 | 4 | 0 | 0 | 0 | 0 | -- | 3-2 | 4.17 | 1.39 |
| 1950-05-22 | Hal Newhouser | L | 29 | L 5-1 | vs WS1 | 1 | 1 | W | 9.0 | 8 | 1 | 1 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 1-0 | 1.00 | 1.22 |
| 1950-05-23 | Fred Hutchinson | R | 31 | W 2-8 | vs WS1 | 6 | 6 | L | 8.0 | 7 | 3 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | -- | 3-3 | 5.25 | 1.52 |
| 1950-05-25 | Art Houtteman | R | 23 | W 4-6 | vs NYA | 6 | 6 | L | 9.0 | 9 | 6 | 6 | 1 | 2 | 7 | 0 | 0 | 0 | -- | 4-3 | 3.17 | 1.15 |
| 1950-05-30 | Art Houtteman | R | 23 | W 0-4 | vs CLE | 7 | 7 | L | 9.0 | 11 | 4 | 4 | 1 | 2 | 0 | 0 | 0 | 0 | -- | 4-4 | 3.29 | 1.19 |
| 1950-05-30 | Hal Newhouser | L | 29 | L 5-2 | vs CLE | 2 | 2 | W | 9.0 | 5 | 2 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | -- | 2-0 | 1.00 | 1.00 |
| 1950-06-02 | Ted Gray | L | 25 | W 8-2 | @ PHA | 7 | 7 | W | 9.0 | 6 | 2 | 2 | 0 | 2 | 8 | 0 | 0 | 0 | -- | 4-2 | 3.78 | 1.30 |
| 1950-06-02 | Fred Hutchinson | R | 31 | W 16-5 | @ PHA | 7 | 7 | W | 9.0 | 15 | 5 | 5 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 4-3 | 5.21 | 1.58 |
| 1950-06-04 | Art Houtteman | R | 23 | W 3-0 | @ WS1 | 8 | 8 | W | 9.0 | 6 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | -- | 5-4 | 2.88 | 1.13 |
| 1950-06-05 | Dizzy Trout | R | 35 | W 7-4 | @ WS1 | 1 | 1 | W | 9.0 | 11 | 4 | 4 | 0 | 1 | 5 | 0 | 0 | 0 | -- | 2-0 | 4.20 | 1.27 |
| 1950-06-06 | Fred Hutchinson | R | 31 | W 11-8 | @ WS1 | 8 | 8 | W | 8.1 | 14 | 8 | 7 | 1 | 4 | 2 | 0 | 0 | 0 | -- | 5-3 | 5.54 | 1.66 |
| 1950-06-07 | Hal Newhouser | L | 29 | L 4-5 | @ NYA | 3 | 3 | L | 7.0 | 12 | 5 | 5 | 3 | 1 | 2 | 0 | 0 | 0 | -- | 2-1 | 2.52 | 1.24 |
| 1950-06-08 | Art Houtteman | R | 23 | L 4-11 | @ NYA | 9 | 9 | L | 5.2 | 6 | 7 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | -- | 5-5 | 3.46 | 1.14 |
| 1950-06-09 | Ted Gray | L | 25 | W 13-7 | @ NYA | 8 | 8 | - | 4.1 | 3 | 3 | 3 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 4-2 | 3.93 | 1.27 |
| 1950-06-10 | Dizzy Trout | R | 35 | W 18-8 | @ BOS | 2 | 2 | W | 6.1 | 10 | 7 | 6 | 1 | 0 | 4 | 0 | 0 | 0 | -- | 3-0 | 5.57 | 1.38 |
| 1950-06-11 | Hal Newhouser | L | 29 | W 6-2 | @ BOS | 4 | 4 | W | 9.0 | 10 | 2 | 2 | 0 | 4 | 6 | 0 | 0 | 0 | -- | 3-1 | 2.38 | 1.32 |
| 1950-06-11 | Fred Hutchinson | R | 31 | W 9-6 | @ BOS | 9 | 9 | - | 5.0 | 8 | 5 | 5 | 1 | 3 | 2 | 0 | 0 | 0 | -- | 5-3 | 5.79 | 1.70 |
| 1950-06-14 | Dizzy Trout | R | 35 | W 2-8 | vs PHA | 3 | 3 | L | 5.0 | 6 | 4 | 4 | 2 | 1 | 2 | 0 | 0 | 0 | -- | 3-1 | 5.88 | 1.38 |
| 1950-06-15 | Fred Hutchinson | R | 31 | L 7-3 | vs PHA | 10 | 10 | W | 9.0 | 8 | 3 | 3 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 6-3 | 5.47 | 1.63 |
| 1950-06-18 | Art Houtteman | R | 23 | L 10-2 | vs BOS | 10 | 10 | W | 9.0 | 7 | 2 | 2 | 2 | 2 | 4 | 0 | 0 | 0 | -- | 6-5 | 3.34 | 1.15 |
| 1950-06-20 | Fred Hutchinson | R | 31 | W 2-4 | vs WS1 | 11 | 11 | L | 8.0 | 10 | 3 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 6-4 | 5.28 | 1.61 |
| 1950-06-22 | Dizzy Trout | R | 35 | W 2-5 | vs WS1 | 4 | 4 | L | 1.2 | 6 | 4 | 4 | 0 | 1 | 1 | 0 | 0 | 0 | -- | 3-2 | 6.75 | 1.54 |
| 1950-06-23 | Ted Gray | L | 25 | L 10-9 | vs NYA | 9 | 9 | - | 3.0 | 8 | 6 | 6 | 4 | 1 | 1 | 0 | 0 | 0 | -- | 5-2 | 4.03 | 1.28 |
| 1950-06-24 | Art Houtteman | R | 23 | L 4-1 | vs NYA | 11 | 11 | W | 9.0 | 9 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | -- | 7-5 | 3.09 | 1.13 |
| 1950-06-25 | Hal Newhouser | L | 29 | W 2-8 | vs NYA | 5 | 5 | L | 6.0 | 12 | 7 | 7 | 2 | 2 | 3 | 0 | 0 | 0 | -- | 3-2 | 3.60 | 1.48 |
| 1950-06-25 | Fred Hutchinson | R | 31 | L 6-3 | vs NYA | 12 | 12 | - | 7.0 | 9 | 2 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | -- | 7-4 | 4.97 | 1.56 |
| 1950-06-26 | Hal White | R | 31 | L 6-4 | vs CHA | 1 | 1 | W | 8.0 | 8 | 4 | 4 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 1-0 | 5.70 | 1.67 |
| 1950-06-28 | Art Houtteman | R | 23 | L 6-2 | vs CHA | 12 | 12 | W | 9.0 | 9 | 2 | 2 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 8-5 | 3.00 | 1.14 |
| 1950-06-29 | Fred Hutchinson | R | 31 | W 3-7 | vs CHA | 13 | 13 | L | 8.0 | 13 | 6 | 6 | 0 | 0 | 5 | 0 | 0 | 0 | -- | 7-5 | 5.11 | 1.57 |
| 1950-06-30 | Hal Newhouser | L | 29 | L 3-11 | @ CLE | 6 | 6 | L | 1.0 | 5 | 6 | 6 | 1 | 3 | 0 | 0 | 0 | 0 | -- | 3-3 | 4.83 | 1.63 |
| 1950-07-01 | Hal White | R | 31 | L 4-7 | @ CLE | 2 | 2 | L | 2.2 | 6 | 6 | 6 | 2 | 2 | 1 | 0 | 0 | 0 | -- | 1-1 | 6.82 | 1.76 |
| 1950-07-02 | Art Houtteman | R | 23 | W 8-5 | @ CLE | 13 | 13 | - | 6.0 | 4 | 4 | 4 | 2 | 3 | 4 | 0 | 0 | 0 | -- | 8-5 | 3.16 | 1.14 |
| 1950-07-02 | Ted Gray | L | 26 | L 3-5 | @ CLE | 10 | 10 | L | 6.0 | 8 | 5 | 5 | 1 | 4 | 9 | 0 | 0 | 0 | -- | 6-3 | 4.32 | 1.32 |
| 1950-07-03 | Fred Hutchinson | R | 31 | W 8-4 | @ CHA | 14 | 14 | W | 5.2 | 8 | 4 | 4 | 2 | 1 | 2 | 0 | 0 | 0 | -- | 8-5 | 5.20 | 1.58 |
| 1950-07-07 | Ted Gray | L | 26 | L 5-2 | vs CLE | 11 | 11 | W | 9.0 | 4 | 2 | 2 | 1 | 4 | 6 | 0 | 0 | 0 | -- | 7-3 | 4.07 | 1.27 |
| 1950-07-08 | Hal Newhouser | L | 29 | L 5-4 | vs CLE | 7 | 7 | W | 7.0 | 6 | 4 | 3 | 3 | 5 | 2 | 0 | 0 | 0 | -- | 5-3 | 4.50 | 1.60 |
| 1950-07-09 | Art Houtteman | R | 23 | W 2-6 | vs CLE | 14 | 14 | L | 5.2 | 10 | 5 | 5 | 1 | 7 | 2 | 0 | 0 | 0 | -- | 8-6 | 3.40 | 1.24 |
| 1950-07-09 | Saul Rogovin | R | 27 | W 2-5 | vs CLE | 1 | 1 | L | 5.1 | 7 | 3 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | -- | 0-1 | 2.77 | 1.46 |
| 1950-07-13 | Hal Newhouser | L | 29 | W 5-2 | @ WS1 | 8 | 8 | W | 9.0 | 6 | 2 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | -- | 6-3 | 3.81 | 1.49 |
| 1950-07-14 | Fred Hutchinson | R | 31 | W 2-0 | @ WS1 | 15 | 15 | W | 9.0 | 6 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | -- | 9-5 | 4.80 | 1.50 |
| 1950-07-16 | Art Houtteman | R | 23 | L 2-5 | @ PHA | 15 | 15 | L | 8.0 | 7 | 5 | 5 | 1 | 4 | 2 | 0 | 0 | 0 | -- | 8-7 | 3.54 | 1.24 |
| 1950-07-16 | Ted Gray | L | 26 | W 7-6 | @ PHA | 12 | 12 | - | 3.0 | 7 | 5 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 7-3 | 4.14 | 1.33 |
| 1950-07-17 | Hal Newhouser | L | 29 | W 8-6 | @ PHA | 9 | 9 | W | 7.0 | 8 | 6 | 5 | 0 | 7 | 2 | 0 | 0 | 0 | -- | 7-3 | 4.09 | 1.56 |
| 1950-07-17 | Saul Rogovin | R | 27 | W 3-1 | @ PHA | 2 | 2 | W | 9.0 | 7 | 1 | 1 | 0 | 6 | 4 | 0 | 0 | 0 | -- | 1-1 | 2.05 | 1.45 |
| 1950-07-19 | Dizzy Trout | R | 35 | W 9-5 | @ BOS | 5 | 5 | W | 7.1 | 8 | 3 | 3 | 1 | 3 | 2 | 0 | 0 | 0 | -- | 4-2 | 5.71 | 1.46 |
| 1950-07-20 | Art Houtteman | R | 23 | L 5-6 | @ BOS | 16 | 16 | L | 10.1 | 12 | 6 | 6 | 2 | 5 | 4 | 0 | 0 | 0 | -- | 8-8 | 3.65 | 1.27 |
| 1950-07-21 | Ted Gray | L | 26 | L 5-14 | @ NYA | 13 | 13 | L | 2.1 | 8 | 7 | 5 | 0 | 2 | 0 | 0 | 0 | 0 | -- | 7-4 | 4.50 | 1.40 |
| 1950-07-22 | Hal Newhouser | L | 29 | L 4-10 | @ NYA | 10 | 10 | L | 3.0 | 8 | 5 | 5 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 7-4 | 4.57 | 1.62 |
| 1950-07-23 | Saul Rogovin | R | 27 | W 6-5 | @ NYA | 3 | 3 | - | 5.0 | 6 | 5 | 5 | 3 | 3 | 1 | 0 | 0 | 0 | -- | 1-1 | 3.33 | 1.52 |
| 1950-07-26 | Art Houtteman | R | 23 | W 0-1 | vs BOS | 17 | 17 | L | 9.0 | 6 | 1 | 1 | 1 | 5 | 2 | 0 | 0 | 0 | -- | 9-9 | 3.44 | 1.25 |
| 1950-07-27 | Dizzy Trout | R | 35 | L 5-1 | vs BOS | 6 | 6 | W | 9.0 | 9 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | -- | 5-2 | 4.86 | 1.37 |
| 1950-07-28 | Hal Newhouser | L | 29 | W 6-7 | vs PHA | 11 | 11 | - | 2.1 | 6 | 5 | 3 | 0 | 2 | 1 | 0 | 0 | 0 | -- | 7-4 | 4.82 | 1.69 |
| 1950-07-29 | Ted Gray | L | 26 | L 8-5 | vs PHA | 14 | 14 | - | 6.0 | 4 | 4 | 4 | 2 | 4 | 1 | 0 | 0 | 0 | -- | 7-4 | 4.59 | 1.40 |
| 1950-08-01 | Dizzy Trout | R | 35 | L 7-3 | vs NYA | 7 | 7 | W | 9.0 | 6 | 3 | 3 | 1 | 1 | 5 | 0 | 0 | 0 | -- | 6-2 | 4.63 | 1.29 |
| 1950-08-02 | Hal White | R | 31 | L 4-0 | vs NYA | 3 | 3 | W | 9.0 | 2 | 0 | 0 | 0 | 2 | 4 | 0 | 0 | 0 | -- | 3-2 | 4.50 | 1.38 |
| 1950-08-03 | Art Houtteman | R | 23 | L 5-2 | vs NYA | 18 | 18 | W | 9.0 | 6 | 2 | 2 | 1 | 2 | 5 | 0 | 0 | 0 | -- | 10-9 | 3.36 | 1.23 |
| 1950-08-04 | Ted Gray | L | 26 | W 2-5 | vs WS1 | 15 | 15 | L | 5.2 | 8 | 5 | 5 | 1 | 2 | 9 | 0 | 0 | 0 | -- | 7-5 | 4.81 | 1.43 |
| 1950-08-05 | Fred Hutchinson | R | 31 | L 9-8 | vs WS1 | 16 | 16 | W | 6.2 | 7 | 5 | 5 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 10-5 | 4.87 | 1.50 |
| 1950-08-06 | Dizzy Trout | R | 35 | L 4-0 | vs WS1 | 8 | 8 | W | 9.0 | 7 | 0 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | -- | 7-2 | 4.11 | 1.27 |
| 1950-08-09 | Fred Hutchinson | R | 31 | W 5-3 | @ CHA | 17 | 17 | W | 9.0 | 9 | 3 | 3 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 11-5 | 4.75 | 1.48 |
| 1950-08-10 | Art Houtteman | R | 23 | W 10-6 | @ CHA | 19 | 19 | W | 8.1 | 12 | 6 | 5 | 0 | 3 | 1 | 0 | 0 | 0 | -- | 11-9 | 3.47 | 1.26 |
| 1950-08-14 | Hal Newhouser | L | 29 | L 2-3 | @ CLE | 12 | 12 | L | 9.1 | 8 | 3 | 3 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 7-5 | 4.77 | 1.64 |
| 1950-08-15 | Art Houtteman | R | 23 | W 4-1 | @ CLE | 20 | 20 | W | 6.0 | 4 | 1 | 1 | 0 | 6 | 4 | 0 | 0 | 0 | -- | 12-9 | 3.40 | 1.27 |
| 1950-08-17 | Hal White | R | 31 | L 8-3 | vs CHA | 4 | 4 | W | 9.0 | 7 | 3 | 2 | 0 | 4 | 3 | 0 | 0 | 0 | -- | 4-2 | 4.15 | 1.35 |
| 1950-08-20 | Fred Hutchinson | R | 31 | L 5-4 | vs SLA | 18 | 18 | - | 4.2 | 7 | 4 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 11-5 | 4.71 | 1.49 |
| 1950-08-21 | Dizzy Trout | R | 35 | L 7-1 | vs SLA | 9 | 9 | W | 9.0 | 4 | 1 | 1 | 0 | 5 | 7 | 0 | 0 | 0 | -- | 8-2 | 3.80 | 1.24 |
| 1950-08-22 | Hal White | R | 31 | L 6-13 | @ NYA | 5 | 5 | L | 2.1 | 4 | 6 | 6 | 0 | 3 | 1 | 0 | 0 | 0 | -- | 4-3 | 4.76 | 1.40 |
| 1950-08-23 | Art Houtteman | R | 23 | L 5-7 | @ NYA | 21 | 21 | L | 4.2 | 6 | 5 | 5 | 0 | 5 | 1 | 0 | 0 | 0 | -- | 12-10 | 3.56 | 1.30 |
| 1950-08-24 | Hal Newhouser | L | 29 | W 6-3 | @ NYA | 13 | 13 | W | 9.0 | 9 | 3 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 8-5 | 4.60 | 1.59 |
| 1950-08-25 | Dizzy Trout | R | 35 | L 2-6 | @ BOS | 10 | 10 | L | 7.0 | 8 | 5 | 5 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 8-3 | 3.99 | 1.27 |
| 1950-08-26 | Hal White | R | 31 | W 8-6 | @ BOS | 6 | 6 | - | 0.0 | 3 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | -- | 4-3 | 5.03 | 1.46 |
| 1950-08-27 | Ray Herbert | R | 21 | L 3-4 | @ PHA | 1 | 1 | L | 8.0 | 6 | 4 | 4 | 1 | 3 | 4 | 0 | 0 | 0 | -- | 0-1 | 4.50 | 1.13 |
| 1950-08-27 | Art Houtteman | R | 23 | W 8-1 | @ PHA | 22 | 22 | W | 9.0 | 9 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 13-10 | 3.44 | 1.30 |
| 1950-08-28 | Hal Newhouser | L | 29 | L 3-4 | @ PHA | 14 | 14 | L | 7.0 | 7 | 4 | 4 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 8-6 | 4.64 | 1.57 |
| 1950-08-29 | Dizzy Trout | R | 35 | L 4-5 | @ WS1 | 11 | 11 | L | 8.0 | 12 | 5 | 5 | 0 | 1 | 4 | 0 | 0 | 0 | -- | 8-4 | 4.11 | 1.30 |
| 1950-08-30 | Fred Hutchinson | R | 31 | L 2-3 | @ WS1 | 19 | 19 | L | 10.1 | 7 | 3 | 3 | 1 | 4 | 5 | 0 | 0 | 0 | -- | 12-6 | 4.47 | 1.42 |
| 1950-08-30 | Hank Borowy | R | 34 | W 10-8 | @ WS1 | 3 | 3 | - | 3.2 | 3 | 3 | 2 | 0 | 6 | 0 | 0 | 0 | 0 | -- | 0-1 | 6.21 | 1.52 |
| 1950-08-31 | Art Houtteman | R | 23 | L 1-2 | @ WS1 | 23 | 23 | L | 8.0 | 5 | 2 | 2 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 13-11 | 3.39 | 1.28 |
| 1950-09-02 | Hal Newhouser | L | 29 | L 8-2 | vs CHA | 15 | 15 | W | 9.0 | 9 | 2 | 2 | 1 | 3 | 7 | 0 | 0 | 0 | -- | 9-6 | 4.42 | 1.55 |
| 1950-09-04 | Dizzy Trout | R | 35 | W 4-5 | vs SLA | 12 | 12 | - | 7.1 | 7 | 4 | 4 | 0 | 3 | 2 | 0 | 0 | 0 | -- | 8-4 | 4.18 | 1.30 |
| 1950-09-05 | Ray Herbert | R | 21 | L 7-4 | vs SLA | 2 | 2 | - | 4.0 | 3 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | -- | 1-1 | 3.00 | 1.13 |
| 1950-09-06 | Hal Newhouser | L | 29 | L 5-3 | vs CLE | 16 | 16 | W | 9.0 | 8 | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | -- | 10-6 | 4.31 | 1.50 |
| 1950-09-07 | Art Houtteman | R | 23 | L 13-13 | vs CLE | 24 | 24 | - | 0.2 | 6 | 7 | 6 | 2 | 0 | 0 | 0 | 0 | 0 | -- | 13-11 | 3.66 | 1.31 |
| 1950-09-09 | Art Houtteman | R | 23 | W 7-0 | @ CHA | 25 | 25 | W | 9.0 | 6 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | -- | 14-11 | 3.50 | 1.29 |
| 1950-09-10 | Hal Newhouser | L | 29 | W 1-0 | @ CHA | 17 | 17 | W | 12.0 | 7 | 0 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | -- | 11-6 | 3.91 | 1.44 |
| 1950-09-12 | Dizzy Trout | R | 35 | L 3-2 | vs WS1 | 13 | 13 | W | 9.0 | 8 | 2 | 2 | 1 | 2 | 3 | 0 | 0 | 0 | -- | 9-4 | 4.02 | 1.29 |
| 1950-09-13 | Fred Hutchinson | R | 31 | L 6-1 | vs WS1 | 20 | 20 | W | 7.0 | 8 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 13-6 | 4.28 | 1.40 |
| 1950-09-14 | Hal Newhouser | L | 29 | W 5-7 | vs NYA | 18 | 18 | L | 4.0 | 8 | 6 | 6 | 2 | 2 | 2 | 0 | 0 | 0 | -- | 11-7 | 4.20 | 1.47 |
| 1950-09-16 | Dizzy Trout | R | 35 | W 1-8 | vs NYA | 14 | 14 | L | 8.1 | 11 | 7 | 7 | 1 | 6 | 4 | 0 | 0 | 0 | -- | 9-5 | 4.22 | 1.33 |
| 1950-09-18 | Hal Newhouser | L | 29 | W 2-3 | vs BOS | 19 | 19 | L | 8.0 | 6 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 11-8 | 4.18 | 1.44 |
| 1950-09-19 | Art Houtteman | R | 23 | L 12-4 | vs PHA | 26 | 26 | W | 9.0 | 8 | 4 | 4 | 2 | 6 | 1 | 0 | 0 | 0 | -- | 15-11 | 3.52 | 1.30 |
| 1950-09-20 | Dizzy Trout | R | 35 | L 6-5 | vs PHA | 15 | 15 | - | 4.1 | 10 | 5 | 5 | 1 | 1 | 2 | 0 | 0 | 0 | -- | 9-5 | 4.43 | 1.37 |
| 1950-09-21 | Fred Hutchinson | R | 31 | L 8-2 | vs PHA | 21 | 21 | W | 9.0 | 13 | 2 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | -- | 14-6 | 4.17 | 1.41 |
| 1950-09-22 | Hal Newhouser | L | 29 | L 3-4 | @ CLE | 20 | 20 | L | 8.0 | 7 | 4 | 4 | 2 | 4 | 4 | 0 | 0 | 0 | -- | 11-9 | 4.20 | 1.44 |
| 1950-09-23 | Art Houtteman | R | 23 | L 2-10 | @ CLE | 27 | 27 | L | 3.1 | 5 | 5 | 5 | 1 | 2 | 1 | 0 | 0 | 0 | -- | 15-12 | 3.67 | 1.31 |
| 1950-09-24 | Ted Gray | L | 26 | L 1-2 | @ CLE | 16 | 16 | L | 9.2 | 6 | 2 | 2 | 1 | 5 | 8 | 0 | 0 | 0 | -- | 7-6 | 4.38 | 1.36 |
| 1950-09-26 | Hal Newhouser | L | 29 | W 1-3 | vs SLA | 21 | 21 | L | 6.0 | 6 | 3 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | -- | 11-10 | 4.21 | 1.43 |
| 1950-09-27 | Art Houtteman | R | 23 | L 5-4 | vs SLA | 28 | 28 | - | 8.2 | 10 | 4 | 4 | 0 | 5 | 1 | 0 | 0 | 0 | -- | 15-12 | 3.70 | 1.33 |
| 1950-09-29 | Ted Gray | L | 26 | W 2-12 | vs CLE | 17 | 17 | L | 4.2 | 7 | 5 | 4 | 0 | 2 | 3 | 0 | 0 | 0 | -- | 7-7 | 4.50 | 1.38 |
| 1950-09-30 | Hal Newhouser | L | 29 | L 3-1 | vs CLE | 22 | 22 | W | 9.0 | 7 | 1 | 1 | 0 | 2 | 4 | 0 | 0 | 0 | -- | 12-10 | 4.04 | 1.41 |
| 1950-10-01 | Marlin Stuart | R | 32 | W 5-7 | vs CLE | 1 | 1 | L | 7.1 | 7 | 5 | 5 | 1 | 6 | 3 | 0 | 0 | 0 | -- | 3-1 | 5.40 | 1.80 |