| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-03-29 | Thu | TOR | AL | A | D | 1 | W | 6-1 | 9 | box - pbp - pit | W1 | 1-0 | 2 | 2 | 1 | 2:51 | 48,115 | Luis Severino | J.A. Happ (L) | Luis Severino | J.A. Happ | None | |
| 2018-03-30 | Fri | TOR | AL | A | N | 2 | W | 4-2 | 9 | box - pbp - pit | W2 | 2-0 | 1 | 4 | 3 | 2:49 | 33,716 | Masahiro Tanaka | Aaron Sanchez (R) | Masahiro Tanaka | Aaron Sanchez | Aroldis Chapman | |
| 2018-03-31 | Sat | TOR | AL | A | D | 3 | L | 3-5 | 9 | box - pbp - pit | L1 | 2-1 | 2 | 4 | 7 | 2:37 | 37,692 | CC Sabathia | Marco Estrada (R) | Ryan Tepera | Dellin Betances | Roberto Osuna | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-04-01 | Sun | TOR | AL | A | D | 4 | L | 4-7 | 9 | box - pbp - pit | L2 | 2-2 | 2 | 8 | 13 | 3:03 | 29,091 | Sonny Gray | Marcus Stroman (R) | Tyler Clippard | David Robertson | Seung Hwan Oh | |
| 2018-04-03 | Tue | TBA | AL | H | D | 5 | W | 11-4 | 9 | box - pbp - pit | W1 | 3-2 | 3 | 6 | 12 | 3:29 | 46,776 | Jordan Montgomery | Chris Archer (R) | Tommy Kahnle | Austin Pruitt | None | |
| 2018-04-04 | Wed | TBA | AL | H | D | 6 | W | 7-2 | 9 | box - pbp - pit | W2 | 4-2 | 2 | 4 | 7 | 2:44 | 40,028 | Luis Severino | Blake Snell (L) | Luis Severino | Blake Snell | None | |
| 2018-04-05 | Thu | BAL | AL | H | N | 7 | L | 2-5 | 9 | box - pbp - pit | L1 | 4-3 | 2 | 6 | 10 | 3:15 | 33,653 | Masahiro Tanaka | Andrew Cashner (R) | Andrew Cashner | Masahiro Tanaka | Brad Brach | |
| 2018-04-06 | Fri | BAL | AL | H | N | 8 | L | 3-7 | 14 | box - pbp - pit | L2 | 4-4 | 3 | 6 | 14 | 5:20 | 34,244 | CC Sabathia | Kevin Gausman (R) | Pedro Araujo | Jonathan Holder | None | |
| 2018-04-07 | Sat | BAL | AL | H | D | 9 | W | 8-3 | 9 | box - pbp - pit | W1 | 5-4 | 2 | 6 | 11 | 3:03 | 34,388 | Sonny Gray | Chris Tillman (R) | Sonny Gray | Chris Tillman | None | |
| 2018-04-08 | Sun | BAL | AL | H | D | 10 | L | 7-8 | 12 | box - pbp - pit | L1 | 5-5 | 3 | 8 | 14 | 4:48 | 37,096 | Jordan Montgomery | Mike Wright (R) | Richard Bleier | Adam Warren | Brad Brach | |
| 2018-04-10 | Tue | BOS | AL | A | N | 11 | L | 1-14 | 9 | box - pbp - pit | L2 | 5-6 | 3 | 8 | 17 | 3:11 | 32,357 | Luis Severino | Chris Sale (L) | Chris Sale | Luis Severino | None | |
| 2018-04-11 | Wed | BOS | AL | A | N | 12 | W | 10-7 | 9 | box - pbp - pit | W1 | 6-6 | 3 | 8 | 16 | 3:59 | 32,400 | Masahiro Tanaka | David Price (L) | Masahiro Tanaka | David Price | None | |
| 2018-04-12 | Thu | BOS | AL | A | N | 13 | L | 3-6 | 9 | box - pbp - pit | L1 | 6-7 | 3 | 8 | 19 | 3:01 | 36,341 | Sonny Gray | Rick Porcello (R) | Rick Porcello | Sonny Gray | Craig Kimbrel | |
| 2018-04-13 | Fri | DET | AL | A | N | 14 | W | 8-6 | 9 | box - pbp - pit | W1 | 7-7 | 3 | 8 | 14 | 3:28 | 21,363 | Jordan Montgomery | Mike Fiers (R) | Jordan Montgomery | Michael Fiers | Aroldis Chapman | |
| 2018-04-16 | Mon | MIA | NL | H | N | 15 | W | 12-1 | 9 | box - pbp - pit | W2 | 8-7 | 3 | 8 | 15 | 3:38 | 32,525 | Luis Severino | Caleb Smith (L) | Luis Severino | Caleb Smith | None | |
| 2018-04-17 | Tue | MIA | NL | H | N | 16 | L | 1-9 | 9 | box - pbp - pit | L1 | 8-8 | 3 | 8 | 15 | 3:11 | 34,005 | Masahiro Tanaka | Jarlin Garcia (L) | Jarlin Garcia | Masahiro Tanaka | None | |
| 2018-04-19 | Thu | TOR | AL | H | N | 17 | W | 4-3 | 9 | box - pbp - pit | W1 | 9-8 | 3 | 7 | 15 | 3:00 | 36,665 | CC Sabathia | Aaron Sanchez (R) | Chad Green | Aaron Sanchez | Aroldis Chapman | |
| 2018-04-20 | Fri | TOR | AL | H | N | 18 | L | 5-8 | 9 | box - pbp - pit | L1 | 9-9 | 3 | 8 | 18 | 3:22 | 39,197 | Sonny Gray | Marco Estrada (R) | Marco Estrada | Domingo German | Roberto Osuna | |
| 2018-04-21 | Sat | TOR | AL | H | D | 19 | W | 9-1 | 9 | box - pbp - pit | W1 | 10-9 | 3 | 8 | 16 | 2:50 | 40,986 | Jordan Montgomery | Marcus Stroman (R) | Jordan Montgomery | Marcus Stroman | None | |
| 2018-04-22 | Sun | TOR | AL | H | D | 20 | W | 5-1 | 9 | box - pbp - pit | W2 | 11-9 | 3 | 7 | 13 | 2:47 | 43,628 | Luis Severino | Jaime Garcia (L) | Luis Severino | Jaime Garcia | None | |
| 2018-04-23 | Mon | MIN | AL | H | N | 21 | W | 14-1 | 9 | box - pbp - pit | W3 | 12-9 | 3 | 6 | 12 | 3:38 | 39,249 | Masahiro Tanaka | Jake Odorizzi (R) | Masahiro Tanaka | Jake Odorizzi | None | |
| 2018-04-24 | Tue | MIN | AL | H | N | 22 | W | 8-3 | 9 | box - pbp - pit | W4 | 13-9 | 3 | 5 | 10 | 3:11 | 39,025 | CC Sabathia | Jose Berrios (R) | CC Sabathia | Jose Berrios | None | |
| 2018-04-25 | Wed | MIN | AL | H | N | 23 | W | 7-4 | 9 | box - pbp - pit | W5 | 14-9 | 2 | 4 | 10 | 3:40 | 39,243 | Sonny Gray | Lance Lynn (R) | Chad Green | Lance Lynn | Aroldis Chapman | |
| 2018-04-26 | Thu | MIN | AL | H | D | 24 | W | 4-3 | 9 | box - pbp - pit | W6 | 15-9 | 2 | 4 | 7 | 3:05 | 40,758 | Jordan Montgomery | Kyle Gibson (R) | Dellin Betances | Fernando Rodney | None | |
| 2018-04-27 | Fri | ANA | AL | A | N | 25 | W | 4-3 | 10 | box - pbp - pit | W7 | 16-9 | 2 | 2 | 5 | 3:15 | 40,416 | Luis Severino | Andrew Heaney (L) | David Robertson | Blake Parker | Aroldis Chapman | |
| 2018-04-28 | Sat | ANA | AL | A | N | 26 | W | 11-1 | 9 | box - pbp - pit | W8 | 17-9 | 2 | 2 | 3 | 3:09 | 44,649 | Masahiro Tanaka | Garrett Richards (R) | Masahiro Tanaka | Garrett Richards | None | |
| 2018-04-29 | Sun | ANA | AL | A | N | 27 | W | 2-1 | 9 | box - pbp - pit | W9 | 18-9 | 2 | 2 | 3 | 3:00 | 44,593 | CC Sabathia | Tyler Skaggs (L) | CC Sabathia | Tyler Skaggs | Aroldis Chapman | |
| 2018-04-30 | Mon | HOU | AL | A | N | 28 | L | 1-2 | 9 | box - pbp - pit | L1 | 18-10 | 2 | 3 | 5 | 2:31 | 30,061 | Sonny Gray | Charlie Morton (R) | Charlie Morton | Sonny Gray | Ken Giles | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-05-01 | Tue | HOU | AL | A | N | 29 | W | 4-0 | 9 | box - pbp - pit | W1 | 19-10 | 2 | 2 | 3 | 2:57 | 34,386 | Jordan Montgomery | Justin Verlander (R) | David Robertson | Ken Giles | None | |
| 2018-05-02 | Wed | HOU | AL | A | N | 30 | W | 4-0 | 9 | box - pbp - pit | W2 | 20-10 | 2 | 2 | 3 | 2:31 | 31,617 | Luis Severino | Dallas Keuchel (L) | Luis Severino | Dallas Keuchel | None | |
| 2018-05-03 | Thu | HOU | AL | A | D | 31 | W | 6-5 | 9 | box - pbp - pit | W3 | 21-10 | 2 | 2 | 3 | 3:11 | 34,838 | Masahiro Tanaka | Lance McCullers (R) | Chasen Shreve | Will Harris | Aroldis Chapman | |
| 2018-05-04 | Fri | CLE | AL | H | N | 32 | W | 7-6 | 9 | box - pbp - pit | W4 | 22-10 | 2 | 2 | 2 | 3:22 | 46,869 | CC Sabathia | Josh Tomlin (R) | Aroldis Chapman | Alexi Ogando | None | |
| 2018-05-05 | Sat | CLE | AL | H | D | 33 | W | 5-2 | 9 | box - pbp - pit | W5 | 23-10 | 2 | 2 | 2 | 2:31 | 43,075 | Sonny Gray | Trevor Bauer (R) | Sonny Gray | Trevor Bauer | David Robertson | |
| 2018-05-06 | Sun | CLE | AL | H | D | 34 | W | 7-4 | 9 | box - pbp - pit | W6 | 24-10 | 2 | 2 | 2 | 3:05 | 40,107 | Domingo German | Mike Clevinger (R) | Chasen Shreve | Cody Allen | None | |
| 2018-05-08 | Tue | BOS | AL | H | N | 35 | W | 3-2 | 9 | box - pbp - pit | W7 | 25-10 | 2 | 2 | 2 | 3:29 | 45,773 | Luis Severino | Drew Pomeranz (L) | David Robertson | Heath Hembree | Aroldis Chapman | |
| 2018-05-09 | Wed | BOS | AL | H | N | 36 | W | 9-6 | 9 | box - pbp - pit | W8 | 26-10 | 1 | 1 | 1 | 3:42 | 47,088 | Masahiro Tanaka | Rick Porcello (R) | Jonathan Holder | Matt Barnes | Aroldis Chapman | |
| 2018-05-10 | Thu | BOS | AL | H | N | 37 | L | 4-5 | 9 | box - pbp - pit | L1 | 26-11 | 2 | 2 | 2 | 3:21 | 46,899 | CC Sabathia | Eduardo Rodriguez (L) | Joe Kelly | Dellin Betances | Craig Kimbrel | |
| 2018-05-11 | Fri | OAK | AL | H | N | 38 | L | 5-10 | 9 | box - pbp - pit | L2 | 26-12 | 2 | 1 | 2 | 3:02 | 43,093 | Sonny Gray | Kendall Graveman (R) | Kendall Graveman | Sonny Gray | Blake Treinen | |
| 2018-05-12 | Sat | OAK | AL | H | D | 39 | W | 7-6 | 11 | box - pbp - pit | W1 | 27-12 | 2 | 2 | 2 | 4:15 | 41,859 | Domingo German | Andrew Triggs (R) | A.J. Cole | Chris Hatcher | None | |
| 2018-05-13 | Sun | OAK | AL | H | D | 40 | W | 6-2 | 9 | box - pbp - pit | W2 | 28-12 | 2 | 2 | 2 | 3:07 | 40,538 | Luis Severino | Brett Anderson (L) | Luis Severino | Brett Anderson | None | |
| 2018-05-15 | Tue | WAS | NL | A | N | 41 | L | 3-5 | 9 | box - pbp - pit | L1 | 28-13 | 1 | 1 | 1 | 2:55 | 41,567 | Masahiro Tanaka | Gio Gonzalez (L) | Wander Suero | Chad Green | Sean Doolittle | |
| 2018-05-18 | Fri | KCA | AL | A | N | 42 | L | 2-5 | 9 | box - pbp - pit | L2 | 28-14 | 2 | 2 | 1 | 2:46 | 26,433 | CC Sabathia | Jake Junis (R) | Jake Junis | CC Sabathia | Kelvin Herrera | |
| 2018-05-19 | Sat | KCA | AL | A | N | 43 | W | 8-3 | 9 | box - pbp - pit | W1 | 29-14 | 1 | 1 | 1 | 2:57 | 33,684 | Luis Severino | Danny Duffy (L) | Luis Severino | Danny Duffy | None | |
| 2018-05-20 | Sun | KCA | AL | A | D | 44 | W | 10-1 | 9 | box - pbp - pit | W2 | 30-14 | 1 | 1 | 1 | 2:31 | 24,121 | Sonny Gray | Eric Skoglund (L) | Sonny Gray | Eric Skoglund | None | |
| 2018-05-21 | Mon | TEX | AL | A | N | 45 | W | 10-5 | 9 | box - pbp - pit | W3 | 31-14 | 1 | 1 | 1 | 3:07 | 29,553 | Masahiro Tanaka | Bartolo Colon (R) | Masahiro Tanaka | Bartolo Colon | None | |
| 2018-05-22 | Tue | TEX | AL | A | N | 46 | L | 4-6 | 9 | box - pbp - pit | L1 | 31-15 | 2 | 2 | 2 | 3:07 | 30,325 | Domingo German | Cole Hamels (L) | Cole Hamels | Domingo German | Keone Kela | |
| 2018-05-23 | Wed | TEX | AL | A | N | 47 | L | 10-12 | 9 | box - pbp - pit | L2 | 31-16 | 2 | 2 | 2 | 3:20 | 31,304 | CC Sabathia | Doug Fister (R) | Alex Claudio | David Robertson | Keone Kela | |
| 2018-05-25 | Fri | ANA | AL | H | N | 48 | W | 2-1 | 9 | box - pbp - pit | W1 | 32-16 | 2 | 2 | 2 | 3:00 | 46,056 | Luis Severino | Andrew Heaney (L) | Chad Green | Jim Johnson | Aroldis Chapman | |
| 2018-05-26 | Sat | ANA | AL | H | N | 49 | L | 4-11 | 9 | box - pbp - pit | L1 | 32-17 | 2 | 2 | 2 | 3:30 | 44,565 | Sonny Gray | Jaime Barria (R) | Jaime Barria | Sonny Gray | None | |
| 2018-05-27 | Sun | ANA | AL | H | D | 50 | W | 3-1 | 9 | box - pbp - pit | W1 | 33-17 | 2 | 2 | 2 | 3:27 | 46,109 | Masahiro Tanaka | Garrett Richards (R) | Masahiro Tanaka | Garrett Richards | Aroldis Chapman | |
| 2018-05-28 | Mon | HOU | AL | H | D | 51 | L | 1-5 | 9 | box - pbp - pit | L1 | 33-18 | 2 | 2 | 2 | 3:14 | 46,583 | Domingo German | Justin Verlander (R) | Justin Verlander | Domingo German | None | |
| 2018-05-29 | Tue | HOU | AL | H | N | 52 | W | 6-5 | 10 | box - pbp - pit | W1 | 34-18 | 2 | 2 | 2 | 3:47 | 45,458 | CC Sabathia | Charlie Morton (R) | Aroldis Chapman | Brad Peacock | None | |
| 2018-05-30 | Wed | HOU | AL | H | N | 53 | W | 5-3 | 9 | box - pbp - pit | W2 | 35-18 | 2 | 2 | 2 | 2:47 | 45,229 | Luis Severino | Dallas Keuchel (L) | Luis Severino | Dallas Keuchel | Aroldis Chapman | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-06-01 | Fri | BAL | AL | A | N | 54 | W | 4-1 | 9 | box - pbp - pit | W3 | 36-18 | 2 | 2 | 2 | 3:03 | 26,500 | Sonny Gray | Andrew Cashner (R) | Sonny Gray | Andrew Cashner | Aroldis Chapman | |
| 2018-06-02 | Sat | BAL | AL | A | N | 55 | W | 8-5 | 9 | box - pbp - pit | W4 | 37-18 | 2 | 2 | 2 | 3:31 | 32,823 | Masahiro Tanaka | Kevin Gausman (R) | Masahiro Tanaka | Kevin Gausman | None | |
| 2018-06-04 | Mon | DET | AL | A | D | 56 | W | 7-4 | 9 | box - pbp - pit | W5 | 38-19 | 2 | 2 | 2 | 2:46 | 28,016 | Luis Severino | Drew Verhagen (R) | Luis Severino | Drew VerHagen | Aroldis Chapman | |
| 2018-06-04 | Mon | DET | AL | A | N | 57 | L | 2-4 | 9 | box - pbp - pit | L1 | 38-19 | 2 | 2 | 2 | 3:07 | 24,165 | Domingo German | Mike Fiers (R) | Michael Fiers | Domingo German | Shane Greene | |
| 2018-06-05 | Tue | TOR | AL | A | N | 58 | W | 7-2 | 9 | box - pbp - pit | W1 | 39-19 | 2 | 2 | 2 | 2:38 | 29,308 | CC Sabathia | Marco Estrada (R) | CC Sabathia | Seung Hwan Oh | None | |
| 2018-06-06 | Wed | TOR | AL | A | N | 59 | W | 3-0 | 13 | box - pbp - pit | W2 | 40-19 | 2 | 2 | 2 | 3:41 | 27,838 | Sonny Gray | Sam Gaviglio (R) | David Robertson | Joe Biagini | Aroldis Chapman | |
| 2018-06-08 | Fri | NYN | NL | A | N | 60 | W | 4-1 | 9 | box - pbp - pit | W3 | 41-19 | 1 | 1 | 1 | 2:28 | 42,961 | Masahiro Tanaka | Jacob DeGrom (R) | Chad Green | Jacob deGrom | Aroldis Chapman | |
| 2018-06-09 | Sat | NYN | NL | A | N | 61 | W | 4-3 | 9 | box - pbp - pit | W4 | 42-19 | 1 | 1 | 1 | 2:57 | 43,603 | Domingo German | Steven Matz (L) | David Robertson | Anthony Swarzak | Aroldis Chapman | |
| 2018-06-10 | Sun | NYN | NL | A | N | 62 | L | 0-2 | 9 | box - pbp - pit | L1 | 42-20 | 1 | 1 | 1 | 2:40 | 36,171 | Luis Severino | Seth Lugo (R) | Seth Lugo | Luis Severino | Anthony Swarzak | |
| 2018-06-12 | Tue | WAS | NL | H | N | 63 | W | 3-0 | 9 | box - pbp - pit | W1 | 43-20 | 1 | 1 | 1 | 2:48 | 44,220 | CC Sabathia | Tanner Roark (R) | CC Sabathia | Tanner Roark | Aroldis Chapman | |
| 2018-06-13 | Wed | WAS | NL | H | N | 64 | L | 4-5 | 9 | box - pbp - pit | L1 | 43-21 | 2 | 2 | 2 | 3:18 | 45,030 | Sonny Gray | Erick Fedde (R) | Justin Miller | Chasen Shreve | Sean Doolittle | |
| 2018-06-14 | Thu | TBA | AL | H | N | 65 | W | 4-3 | 9 | box - pbp - pit | W1 | 44-21 | 2 | 2 | 2 | 2:49 | 45,066 | Domingo German | Blake Snell (L) | Domingo German | Blake Snell | Aroldis Chapman | |
| 2018-06-15 | Fri | TBA | AL | H | N | 66 | W | 5-0 | 9 | box - pbp - pit | W2 | 45-21 | 1 | 1 | 1 | 2:44 | 45,112 | Jonathan Loaisiga | Nathan Eovaldi (R) | Jonathan Loaisiga | Nathan Eovaldi | None | |
| 2018-06-16 | Sat | TBA | AL | H | D | 67 | W | 4-1 | 9 | box - pbp - pit | W3 | 46-21 | 1 | 1 | 1 | 2:47 | 46,249 | Luis Severino | Ryne Stanek (R) | Luis Severino | Ryan Yarbrough | Aroldis Chapman | |
| 2018-06-17 | Sun | TBA | AL | H | D | 68 | L | 1-3 | 9 | box - pbp - pit | L1 | 46-22 | 1 | 1 | 1 | 2:45 | 46,400 | CC Sabathia | Wilmer Font (R) | Chaz Roe | CC Sabathia | Sergio Romo | |
| 2018-06-18 | Mon | WAS | NL | A | N | 69 | W | 4-2 | 9 | box - pbp - pit | W1 | 47-22 | 1 | 1 | 1 | 3:26 | 42,723 | Sonny Gray | Erick Fedde (R) | Sonny Gray | Erick Fedde | Aroldis Chapman | |
| 2018-06-19 | Tue | SEA | AL | H | N | 70 | W | 7-2 | 9 | box - pbp - pit | W2 | 48-22 | 1 | 1 | 1 | 2:28 | 45,122 | Domingo German | Marco Gonzales (L) | Domingo German | Marco Gonzales | None | |
| 2018-06-20 | Wed | SEA | AL | H | N | 71 | W | 7-5 | 9 | box - pbp - pit | W3 | 49-22 | 1 | 1 | 1 | 3:28 | 46,047 | Jonathan Loaisiga | Felix Hernandez (R) | Aroldis Chapman | Ryan Cook | None | |
| 2018-06-21 | Thu | SEA | AL | H | D | 72 | W | 4-3 | 9 | box - pbp - pit | W4 | 50-22 | 1 | 1 | 1 | 2:51 | 46,658 | Luis Severino | James Paxton (L) | Luis Severino | James Paxton | Aroldis Chapman | |
| 2018-06-22 | Fri | TBA | AL | A | N | 73 | L | 1-2 | 9 | box - pbp - pit | L1 | 50-23 | 1 | 1 | 1 | 3:08 | 27,252 | CC Sabathia | Ryne Stanek (R) | Ryan Yarbrough | CC Sabathia | Sergio Romo | |
| 2018-06-23 | Sat | TBA | AL | A | D | 74 | L | 0-4 | 9 | box - pbp - pit | L2 | 50-24 | 1 | 1 | 1 | 2:39 | 29,831 | Sonny Gray | Wilmer Font (R) | Wilmer Font | Sonny Gray | None | |
| 2018-06-24 | Sun | TBA | AL | A | D | 75 | L | 6-7 | 12 | box - pbp - pit | L3 | 50-25 | 1 | 1 | 1 | 4:16 | 23,667 | Domingo German | Matt Andriese (R) | Ryan Yarbrough | Chasen Shreve | None | |
| 2018-06-25 | Mon | PHI | NL | A | N | 76 | W | 4-2 | 9 | box - pbp - pit | W1 | 51-25 | 1 | 1 | 1 | 3:20 | 44,136 | Jonathan Loaisiga | Vincent Velasquez (R) | Jonathan Loaisiga | Vincent Velasquez | Aroldis Chapman | |
| 2018-06-26 | Tue | PHI | NL | A | N | 77 | W | 6-0 | 9 | box - pbp - pit | W2 | 52-25 | 1 | 1 | 1 | 2:38 | 43,568 | Luis Severino | Jake Arrieta (R) | Luis Severino | Jake Arrieta | None | |
| 2018-06-27 | Wed | PHI | NL | A | N | 78 | L | 0-3 | 9 | box - pbp - pit | L1 | 52-26 | 2 | 2 | 2 | 2:43 | 42,028 | Luis Cessa | Zach Eflin (R) | Zach Eflin | Luis Cessa | Seranthony Dominguez | |
| 2018-06-29 | Fri | BOS | AL | H | N | 79 | W | 8-1 | 9 | box - pbp - pit | W1 | 53-26 | 1 | 1 | 1 | 2:41 | 47,120 | CC Sabathia | Eduardo Rodriguez (L) | CC Sabathia | Eduardo Rodriguez | None | |
| 2018-06-30 | Sat | BOS | AL | H | N | 80 | L | 0-11 | 9 | box - pbp - pit | L1 | 53-27 | 2 | 2 | 2 | 3:17 | 47,125 | Sonny Gray | Chris Sale (L) | Chris Sale | Sonny Gray | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-07-01 | Sun | BOS | AL | H | N | 81 | W | 11-1 | 9 | box - pbp - pit | W1 | 54-27 | 1 | 1 | 1 | 3:14 | 46,795 | Luis Severino | David Price (L) | Luis Severino | David Price | None | |
| 2018-07-02 | Mon | ATL | NL | H | N | 82 | L | 3-5 | 11 | box - pbp - pit | L1 | 54-28 | 2 | 2 | 2 | 3:53 | 43,792 | Jonathan Loaisiga | Anibal Sanchez (R) | Jesse Biddle | David Robertson | A.J. Minter | |
| 2018-07-03 | Tue | ATL | NL | H | N | 83 | W | 8-5 | 9 | box - pbp - pit | W1 | 55-28 | 2 | 2 | 2 | 3:46 | 45,448 | Domingo German | Sean Newcomb (L) | A.J. Cole | Sean Newcomb | Aroldis Chapman | |
| 2018-07-04 | Wed | ATL | NL | H | D | 84 | W | 6-2 | 9 | box - pbp - pit | W2 | 56-28 | 2 | 2 | 2 | 3:07 | 46,658 | CC Sabathia | Julio Teheran (R) | CC Sabathia | Julio Teheran | None | |
| 2018-07-06 | Fri | TOR | AL | A | N | 85 | L | 2-6 | 9 | box - pbp - pit | L1 | 56-29 | 2 | 2 | 2 | 3:07 | 37,254 | Sonny Gray | Sam Gaviglio (R) | Joe Biagini | Sonny Gray | None | |
| 2018-07-07 | Sat | TOR | AL | A | D | 86 | W | 8-5 | 9 | box - pbp - pit | W1 | 57-29 | 2 | 2 | 2 | 3:31 | 44,352 | Luis Severino | J.A. Happ (L) | Luis Severino | J.A. Happ | None | |
| 2018-07-08 | Sun | TOR | AL | A | D | 87 | W | 2-1 | 10 | box - pbp - pit | W2 | 58-29 | 2 | 2 | 2 | 2:51 | 39,866 | Domingo German | Ryan Borucki (L) | Chad Green | Tyler Clippard | David Robertson | |
| 2018-07-09 | Mon | BAL | AL | A | D | 88 | L | 4-5 | 9 | box - pbp - pit | L1 | 59-30 | 2 | 2 | 2 | 2:55 | 0 | CC Sabathia | Jimmy Yacabonis (R) | Mike Wright | CC Sabathia | Zach Britton | |
| 2018-07-09 | Mon | BAL | AL | A | N | 89 | W | 10-2 | 9 | box - pbp - pit | W1 | 59-30 | 2 | 2 | 2 | 3:13 | 26,340 | Luis Cessa | Yefry Ramirez (R) | Luis Cessa | Yefry Ramirez | Giovanny Gallegos | |
| 2018-07-10 | Tue | BAL | AL | A | N | 90 | L | 5-6 | 9 | box - pbp - pit | L1 | 59-31 | 2 | 3 | 3 | 3:07 | 18,418 | Masahiro Tanaka | Andrew Cashner (R) | Zach Britton | Dellin Betances | None | |
| 2018-07-11 | Wed | BAL | AL | A | N | 91 | W | 9-0 | 9 | box - pbp - pit | W1 | 60-31 | 2 | 2 | 2 | 3:22 | 17,808 | Sonny Gray | Dylan Bundy (R) | Sonny Gray | Dylan Bundy | None | |
| 2018-07-12 | Thu | CLE | AL | A | N | 92 | W | 7-4 | 9 | box - pbp - pit | W2 | 61-31 | 2 | 2 | 2 | 3:07 | 31,267 | Luis Severino | Corey Kluber (R) | David Robertson | Corey Kluber | Aroldis Chapman | |
| 2018-07-13 | Fri | CLE | AL | A | N | 93 | L | 5-6 | 9 | box - pbp - pit | L1 | 61-32 | 2 | 2 | 2 | 2:59 | 35,078 | Domingo German | Shane Bieber (R) | Shane Bieber | Domingo German | Cody Allen | |
| 2018-07-14 | Sat | CLE | AL | A | N | 94 | W | 5-4 | 9 | box - pbp - pit | W1 | 62-32 | 2 | 2 | 2 | 3:10 | 35,353 | CC Sabathia | Mike Clevinger (R) | David Robertson | Mike Clevinger | Aroldis Chapman | |
| 2018-07-15 | Sun | CLE | AL | A | D | 95 | L | 2-5 | 9 | box - pbp - pit | L1 | 62-33 | 2 | 2 | 2 | 2:52 | 32,644 | Masahiro Tanaka | Trevor Bauer (R) | Carlos Carrasco | Chad Green | Cody Allen | |
| 2018-07-20 | Fri | NYN | NL | H | N | 96 | L | 5-7 | 9 | box - pbp - pit | L2 | 62-34 | 2 | 3 | 3 | 3:46 | 47,175 | Domingo German | Noah Syndergaard (R) | Noah Syndergaard | Domingo German | Robert Gsellman | |
| 2018-07-21 | Sat | NYN | NL | H | D | 97 | W | 7-6 | 9 | box - pbp - pit | W1 | 63-34 | 2 | 3 | 3 | 3:01 | 47,102 | Sonny Gray | Steven Matz (L) | Sonny Gray | Steven Matz | Chasen Shreve | |
| 2018-07-23 | Mon | TBA | AL | A | N | 98 | L | 6-7 | 9 | box - pbp - pit | L1 | 63-35 | 2 | 3 | 3 | 3:26 | 14,670 | Luis Severino | Hunter Wood (R) | Matt Andriese | Luis Severino | Jose Alvarado | |
| 2018-07-24 | Tue | TBA | AL | A | N | 99 | W | 4-0 | 9 | box - pbp - pit | W1 | 64-35 | 2 | 3 | 3 | 2:37 | 19,579 | Masahiro Tanaka | Yonny Chirinos (R) | Masahiro Tanaka | Yonny Chirinos | None | |
| 2018-07-25 | Wed | TBA | AL | A | D | 100 | L | 2-3 | 9 | box - pbp - pit | L1 | 64-36 | 2 | 3 | 3 | 2:46 | 27,372 | Luis Cessa | Ryne Stanek (R) | Diego Castillo | Luis Cessa | Sergio Romo | |
| 2018-07-26 | Thu | KCA | AL | H | N | 101 | W | 7-2 | 9 | box - pbp - pit | W1 | 65-36 | 2 | 3 | 3 | 2:58 | 46,965 | Sonny Gray | Jake Junis (R) | Sonny Gray | Jake Junis | None | |
| 2018-07-28 | Sat | KCA | AL | H | D | 102 | L | 5-10 | 9 | box - pbp - pit | L1 | 66-37 | 2 | 2 | 2 | 3:06 | 46,571 | Luis Severino | Brad Keller (R) | Brad Keller | Luis Severino | None | |
| 2018-07-28 | Sat | KCA | AL | H | N | 103 | W | 5-4 | 9 | box - pbp - pit | W1 | 66-37 | 2 | 2 | 2 | 3:27 | 45,043 | CC Sabathia | Heath Fillmyer (R) | Dellin Betances | Brian Flynn | Aroldis Chapman | |
| 2018-07-29 | Sun | KCA | AL | H | D | 104 | W | 6-3 | 9 | box - pbp - pit | W2 | 67-37 | 2 | 2 | 2 | 2:51 | 46,192 | J.A. Happ | Burch Smith (R) | J.A. Happ | Burch Smith | Aroldis Chapman | |
| 2018-07-31 | Tue | BAL | AL | H | N | 105 | W | 6-3 | 9 | box - pbp - pit | W3 | 68-37 | 2 | 2 | 2 | 3:11 | 46,473 | Masahiro Tanaka | Yefry Ramirez (R) | Masahiro Tanaka | Yefry Ramirez | Aroldis Chapman | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-08-01 | Wed | BAL | AL | H | D | 106 | L | 5-7 | 9 | box - pbp - pit | L1 | 68-38 | 2 | 2 | 2 | 3:08 | 47,206 | Sonny Gray | Alex Cobb (R) | Alex Cobb | Sonny Gray | None | |
| 2018-08-02 | Thu | BOS | AL | A | N | 107 | L | 7-15 | 9 | box - pbp - pit | L2 | 68-39 | 2 | 2 | 2 | 3:25 | 37,317 | CC Sabathia | Brian Johnson (L) | Brian Johnson | Jonathan Holder | None | |
| 2018-08-03 | Fri | BOS | AL | A | N | 108 | L | 1-4 | 9 | box - pbp - pit | L3 | 68-40 | 2 | 3 | 3 | 2:15 | 37,231 | Luis Severino | Rick Porcello (R) | Rick Porcello | Luis Severino | None | |
| 2018-08-04 | Sat | BOS | AL | A | D | 109 | L | 1-4 | 9 | box - pbp - pit | L4 | 68-41 | 2 | 3 | 3 | 2:33 | 36,699 | Chance Adams | Nathan Eovaldi (R) | Nathan Eovaldi | Chance Adams | None | |
| 2018-08-05 | Sun | BOS | AL | A | N | 110 | L | 4-5 | 10 | box - pbp - pit | L5 | 68-42 | 2 | 3 | 3 | 4:39 | 37,830 | Masahiro Tanaka | David Price (L) | Matt Barnes | Jonathan Holder | None | |
| 2018-08-06 | Mon | CHA | AL | A | N | 111 | W | 7-0 | 9 | box - pbp - pit | W1 | 69-42 | 2 | 3 | 3 | 2:59 | 22,084 | Lance Lynn | Dylan Covey (R) | Lance Lynn | Dylan Covey | None | |
| 2018-08-07 | Tue | CHA | AL | A | N | 112 | W | 4-3 | 13 | box - pbp - pit | W2 | 70-42 | 2 | 3 | 3 | 4:26 | 19,643 | CC Sabathia | Reynaldo Lopez (R) | Sonny Gray | Luis Avilan | None | |
| 2018-08-08 | Wed | CHA | AL | A | N | 113 | W | 7-3 | 9 | box - pbp - pit | W3 | 71-42 | 2 | 3 | 3 | 3:05 | 27,038 | Luis Severino | Lucas Giolito (R) | Luis Severino | Lucas Giolito | None | |
| 2018-08-09 | Thu | TEX | AL | H | N | 114 | W | 7-3 | 9 | box - pbp - pit | W4 | 72-42 | 2 | 2 | 2 | 2:31 | 43,455 | J.A. Happ | Ariel Jurado (R) | J.A. Happ | Ariel Jurado | None | |
| 2018-08-10 | Fri | TEX | AL | H | N | 115 | L | 7-12 | 9 | box - pbp - pit | L1 | 72-43 | 2 | 2 | 2 | 3:34 | 45,198 | Masahiro Tanaka | Mike Minor (L) | Mike Minor | Masahiro Tanaka | None | |
| 2018-08-11 | Sat | TEX | AL | H | D | 116 | W | 5-3 | 9 | box - pbp - pit | W1 | 73-43 | 2 | 2 | 2 | 3:16 | 45,933 | Lance Lynn | Drew Hutchison (R) | Dellin Betances | Chris Martin | Aroldis Chapman | |
| 2018-08-12 | Sun | TEX | AL | H | D | 117 | W | 7-2 | 9 | box - pbp - pit | W2 | 74-43 | 2 | 2 | 2 | 2:59 | 41,304 | CC Sabathia | Martin Perez (L) | CC Sabathia | Martin Perez | None | |
| 2018-08-13 | Mon | NYN | NL | H | N | 118 | L | 5-8 | 9 | box - pbp - pit | L1 | 74-44 | 2 | 2 | 2 | 3:18 | 47,233 | Luis Severino | Jacob DeGrom (R) | Jacob deGrom | Luis Severino | Robert Gsellman | |
| 2018-08-14 | Tue | TBA | AL | H | N | 119 | W | 4-1 | 9 | box - pbp - pit | W1 | 75-44 | 2 | 2 | 2 | 2:32 | 40,393 | J.A. Happ | Hunter Wood (R) | J.A. Happ | Hunter Wood | Aroldis Chapman | |
| 2018-08-15 | Wed | TBA | AL | H | N | 120 | L | 1-6 | 9 | box - pbp - pit | L1 | 75-45 | 2 | 2 | 2 | 3:17 | 42,716 | Luis Cessa | Jake Faria (R) | Ryan Yarbrough | Luis Cessa | None | |
| 2018-08-16 | Thu | TBA | AL | H | D | 121 | L | 1-3 | 9 | box - pbp - pit | L2 | 75-46 | 2 | 2 | 2 | 3:22 | 41,033 | Masahiro Tanaka | Blake Snell (L) | Blake Snell | Masahiro Tanaka | Adam Kolarek | |
| 2018-08-17 | Fri | TOR | AL | H | N | 122 | W | 7-5 | 7 | box - pbp - pit | W1 | 76-46 | 2 | 2 | 2 | 2:32 | 42,121 | Lance Lynn | Marcus Stroman (R) | Chad Green | Joe Biagini | David Robertson | |
| 2018-08-18 | Sat | TOR | AL | H | D | 123 | W | 11-6 | 9 | box - pbp - pit | W2 | 77-46 | 2 | 2 | 2 | 3:29 | 44,778 | Luis Severino | Sean Reid-Foley (R) | Luis Severino | Sean Reid-Foley | None | |
| 2018-08-19 | Sun | TOR | AL | H | D | 124 | W | 10-2 | 9 | box - pbp - pit | W3 | 78-46 | 2 | 2 | 2 | 3:18 | 43,176 | J.A. Happ | Ryan Borucki (L) | J.A. Happ | Ryan Borucki | None | |
| 2018-08-21 | Tue | MIA | NL | A | N | 125 | W | 2-1 | 12 | box - pbp - pit | W4 | 79-46 | 2 | 2 | 2 | 4:14 | 26,275 | Masahiro Tanaka | Pablo Lopez (R) | A.J. Cole | Javy Guerra | Tommy Kahnle | |
| 2018-08-22 | Wed | MIA | NL | A | N | 126 | L | 3-9 | 9 | box - pbp - pit | L1 | 79-47 | 2 | 2 | 2 | 3:25 | 25,547 | Lance Lynn | Trevor Richards (R) | Jarlin Garcia | Lance Lynn | None | |
| 2018-08-24 | Fri | BAL | AL | A | N | 127 | W | 7-5 | 10 | box - pbp - pit | W1 | 80-47 | 2 | 2 | 2 | 3:29 | 27,150 | CC Sabathia | Alex Cobb (R) | Chad Green | Cody Carroll | Zach Britton | |
| 2018-08-25 | Sat | BAL | AL | A | D | 128 | W | 10-3 | 9 | box - pbp - pit | W2 | 82-47 | 2 | 2 | 2 | 3:06 | 32,445 | J.A. Happ | Jimmy Yacabonis (R) | J.A. Happ | Jimmy Yacabonis | Luis Cessa | |
| 2018-08-25 | Sat | BAL | AL | A | N | 129 | W | 5-1 | 9 | box - pbp - pit | W3 | 82-47 | 2 | 2 | 2 | 2:50 | 26,236 | Sonny Gray | Andrew Cashner (R) | Sonny Gray | Andrew Cashner | Dellin Betances | |
| 2018-08-26 | Sun | BAL | AL | A | N | 130 | W | 5-3 | 9 | box - pbp - pit | W4 | 83-47 | 2 | 2 | 2 | 3:18 | 17,343 | Luis Severino | Dylan Bundy (R) | Luis Severino | Dylan Bundy | David Robertson | |
| 2018-08-27 | Mon | CHA | AL | H | N | 131 | L | 2-6 | 9 | box - pbp - pit | L1 | 83-48 | 2 | 2 | 2 | 3:02 | 41,456 | Masahiro Tanaka | Carlos Rodon (L) | Carlos Rodon | Masahiro Tanaka | None | |
| 2018-08-28 | Tue | CHA | AL | H | N | 132 | W | 5-4 | 9 | box - pbp - pit | W1 | 84-48 | 2 | 2 | 2 | 3:03 | 40,015 | Lance Lynn | James Shields (R) | Dellin Betances | Dylan Covey | None | |
| 2018-08-29 | Wed | CHA | AL | H | N | 133 | L | 1-4 | 9 | box - pbp - pit | L1 | 84-49 | 2 | 2 | 2 | 2:55 | 40,887 | CC Sabathia | Reynaldo Lopez (R) | Reynaldo Lopez | CC Sabathia | Jace Fry | |
| 2018-08-30 | Thu | DET | AL | H | N | 134 | L | 7-8 | 9 | box - pbp - pit | L2 | 84-50 | 2 | 2 | 2 | 3:32 | 37,195 | J.A. Happ | Francisco Liriano (L) | Alex Wilson | Dellin Betances | Shane Greene | |
| 2018-08-31 | Fri | DET | AL | H | N | 135 | W | 7-5 | 9 | box - pbp - pit | W1 | 85-50 | 2 | 2 | 2 | 3:10 | 41,026 | Luis Severino | Jordan Zimmermann (R) | Zach Britton | Joe Jimenez | David Robertson | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-09-01 | Sat | DET | AL | H | D | 136 | W | 2-1 | 9 | box - pbp - pit | W2 | 86-50 | 2 | 2 | 2 | 3:00 | 42,816 | Masahiro Tanaka | Daniel Norris (L) | Masahiro Tanaka | Daniel Norris | Dellin Betances | |
| 2018-09-02 | Sun | DET | AL | H | D | 137 | L | 7-11 | 9 | box - pbp - pit | L1 | 86-51 | 2 | 2 | 2 | 3:41 | 43,721 | Lance Lynn | Matt Boyd (L) | Matt Boyd | Lance Lynn | None | |
| 2018-09-03 | Mon | OAK | AL | A | D | 138 | L | 3-6 | 9 | box - pbp - pit | L2 | 86-52 | 2 | 2 | 2 | 3:04 | 40,546 | CC Sabathia | Trevor Cahill (R) | Trevor Cahill | CC Sabathia | Blake Treinen | |
| 2018-09-04 | Tue | OAK | AL | A | N | 139 | W | 5-1 | 9 | box - pbp - pit | W1 | 87-52 | 2 | 2 | 2 | 3:12 | 17,536 | J.A. Happ | Liam Hendriks (R) | David Robertson | Fernando Rodney | None | |
| 2018-09-05 | Wed | OAK | AL | A | N | 140 | L | 2-8 | 9 | box - pbp - pit | L1 | 87-53 | 2 | 3 | 3 | 2:53 | 21,004 | Luis Severino | Mike Fiers (R) | Michael Fiers | Luis Severino | None | |
| 2018-09-07 | Fri | SEA | AL | A | N | 141 | W | 4-0 | 9 | box - pbp - pit | W1 | 88-53 | 2 | 3 | 2 | 2:32 | 32,195 | Masahiro Tanaka | James Paxton (L) | Masahiro Tanaka | James Paxton | None | |
| 2018-09-08 | Sat | SEA | AL | A | N | 142 | W | 4-2 | 9 | box - pbp - pit | W2 | 89-53 | 2 | 3 | 2 | 2:49 | 38,733 | Lance Lynn | Felix Hernandez (R) | Lance Lynn | Nick Vincent | Dellin Betances | |
| 2018-09-09 | Sun | SEA | AL | A | D | 143 | L | 2-3 | 9 | box - pbp - pit | L1 | 89-54 | 2 | 3 | 2 | 3:05 | 34,917 | CC Sabathia | Erasmo Ramirez (R) | Alex Colome | Dellin Betances | Edwin Diaz | |
| 2018-09-10 | Mon | MIN | AL | A | N | 144 | W | 7-2 | 9 | box - pbp - pit | W1 | 90-54 | 2 | 2 | 2 | 3:39 | 21,565 | J.A. Happ | Kyle Gibson (R) | J.A. Happ | Kyle Gibson | None | |
| 2018-09-11 | Tue | MIN | AL | A | N | 145 | L | 5-10 | 9 | box - pbp - pit | L1 | 90-55 | 2 | 3 | 3 | 3:04 | 20,343 | Sonny Gray | Tyler Duffey (R) | Kohl Stewart | Sonny Gray | None | |
| 2018-09-12 | Wed | MIN | AL | A | N | 146 | L | 1-3 | 9 | box - pbp - pit | L2 | 90-56 | 2 | 3 | 3 | 2:46 | 24,134 | Luis Severino | Jake Odorizzi (R) | Jake Odorizzi | Luis Severino | Trevor Hildenberger | |
| 2018-09-14 | Fri | TOR | AL | H | N | 147 | W | 11-0 | 9 | box - pbp - pit | W1 | 91-56 | 2 | 3 | 3 | 3:07 | 40,138 | Masahiro Tanaka | Marco Estrada (R) | Masahiro Tanaka | Marco Estrada | Luis Cessa | |
| 2018-09-15 | Sat | TOR | AL | H | D | 148 | L | 7-8 | 9 | box - pbp - pit | L1 | 91-57 | 2 | 3 | 3 | 3:54 | 43,130 | CC Sabathia | Sean Reid-Foley (R) | Sean Reid-Foley | CC Sabathia | Ken Giles | |
| 2018-09-16 | Sun | TOR | AL | H | D | 149 | L | 2-3 | 9 | box - pbp - pit | L2 | 91-58 | 2 | 3 | 3 | 2:50 | 41,758 | Lance Lynn | Thomas Pannone (L) | Thomas Pannone | Dellin Betances | Ken Giles | |
| 2018-09-18 | Tue | BOS | AL | H | N | 150 | W | 3-2 | 9 | box - pbp - pit | W1 | 92-58 | 2 | 3 | 3 | 3:13 | 38,695 | J.A. Happ | Nathan Eovaldi (R) | Chad Green | Brandon Workman | Zach Britton | |
| 2018-09-19 | Wed | BOS | AL | H | N | 151 | W | 10-1 | 9 | box - pbp - pit | W2 | 93-58 | 2 | 3 | 3 | 3:17 | 43,297 | Luis Severino | David Price (L) | Luis Severino | David Price | None | |
| 2018-09-20 | Thu | BOS | AL | H | N | 152 | L | 6-11 | 9 | box - pbp - pit | L1 | 93-59 | 2 | 3 | 3 | 4:02 | 47,351 | Masahiro Tanaka | Eduardo Rodriguez (L) | Steven Wright | Chad Green | None | |
| 2018-09-21 | Fri | BAL | AL | H | N | 153 | W | 10-8 | 9 | box - pbp - pit | W1 | 94-59 | 2 | 3 | 3 | 3:35 | 39,903 | CC Sabathia | Yefry Ramirez (R) | CC Sabathia | Yefry Ramirez | Dellin Betances | |
| 2018-09-22 | Sat | BAL | AL | H | D | 154 | W | 3-2 | 11 | box - pbp - pit | W2 | 95-59 | 2 | 3 | 3 | 3:53 | 40,185 | Lance Lynn | David Hess (R) | Tommy Kahnle | Paul Fry | None | |
| 2018-09-23 | Sun | BAL | AL | H | D | 155 | L | 3-6 | 9 | box - pbp - pit | L1 | 95-60 | 2 | 3 | 3 | 3:19 | 43,606 | J.A. Happ | Alex Cobb (R) | Ryan Meisinger | A.J. Cole | Mychal Givens | |
| 2018-09-24 | Mon | TBA | AL | A | N | 156 | W | 4-1 | 9 | box - pbp - pit | W1 | 96-60 | 2 | 3 | 3 | 3:01 | 13,832 | Jonathan Holder | Diego Castillo (R) | Sonny Gray | Ryan Yarbrough | Zach Britton | |
| 2018-09-25 | Tue | TBA | AL | A | N | 157 | W | 9-2 | 9 | box - pbp - pit | W2 | 97-60 | 2 | 3 | 3 | 3:14 | 10,953 | Luis Severino | Jake Faria (R) | Luis Severino | Jacob Faria | None | |
| 2018-09-26 | Wed | TBA | AL | A | N | 158 | L | 7-8 | 9 | box - pbp - pit | L1 | 97-61 | 2 | 3 | 3 | 3:52 | 11,325 | Masahiro Tanaka | Ryne Stanek (R) | Yonny Chirinos | Masahiro Tanaka | Sergio Romo | |
| 2018-09-27 | Thu | TBA | AL | A | D | 159 | W | 12-1 | 9 | box - pbp - pit | W1 | 98-61 | 2 | 3 | 3 | 2:49 | 12,349 | CC Sabathia | Jaime Schultz (R) | CC Sabathia | Jaime Schultz | None | |
| 2018-09-28 | Fri | BOS | AL | A | N | 160 | W | 11-6 | 9 | box - pbp - pit | W2 | 99-61 | 2 | 3 | 3 | 3:27 | 36,779 | J.A. Happ | Brian Johnson (L) | J.A. Happ | Brian Johnson | None | |
| 2018-09-29 | Sat | BOS | AL | A | D | 161 | W | 8-5 | 9 | box - pbp - pit | W3 | 100-61 | 2 | 3 | 3 | 3:40 | 36,375 | Domingo German | Nathan Eovaldi (R) | Lance Lynn | Eduardo Rodriguez | Aroldis Chapman | |
| 2018-09-30 | Sun | BOS | AL | A | D | 162 | L | 2-10 | 9 | box - pbp - pit | L1 | 100-62 | 2 | 3 | 3 | 3:20 | 36,201 | Luis Cessa | Rick Porcello (R) | Eduardo Rodriguez | Luis Cessa | None |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 162 | 100 | 62 | .617 | 851 | 669 | +182 |
| Home Games | 81 | 53 | 28 | .654 | 453 | 352 | +101 |
| Away Games | 81 | 47 | 34 | .580 | 398 | 317 | +81 |
| Night Games | 110 | 69 | 41 | .627 | 577 | 460 | +117 |
| Day Games | 52 | 31 | 21 | .596 | 274 | 209 | +65 |
| March/April | 28 | 18 | 10 | .643 | 164 | 118 | +46 |
| May | 25 | 17 | 8 | .680 | 135 | 111 | +24 |
| June | 27 | 18 | 9 | .667 | 107 | 76 | +31 |
| July | 25 | 15 | 10 | .600 | 140 | 102 | +38 |
| August | 30 | 17 | 13 | .567 | 155 | 141 | +14 |
| Sept/Oct | 27 | 15 | 12 | .556 | 150 | 121 | +29 |
| 1-Run Games | 40 | 23 | 17 | .575 | 169 | 163 | +6 |
| Close Games (1-2-3 Runs) | 99 | 57 | 42 | .576 | 441 | 410 | +31 |
| Blowouts (7+ runs) | 23 | 17 | 6 | .739 | 189 | 92 | +97 |
| Extra Innings | 14 | 9 | 5 | .643 | 61 | 58 | +3 |
| Shutouts | 15 | 11 | 4 | .733 | 60 | 20 | +40 |
| vs LHSP | 45 | 30 | 15 | .667 | 247 | 194 | +53 |
| vs RHSP | 117 | 70 | 47 | .598 | 604 | 475 | +129 |
| vs Division | 76 | 44 | 32 | .579 | 415 | 320 | +95 |
| vs League | 142 | 89 | 53 | .627 | 767 | 593 | +174 |
| InterLeague | 20 | 11 | 9 | .550 | 84 | 76 | +8 |
