| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-03-29 | Thu | OAK | AL | A | D | 1 | L | 5-6 | 11 | box - pbp - pit | L1 | 0-1 | 4 | 10 | 19 | 4:02 | 27,764 | Garrett Richards | Kendall Graveman (R) | Chris Hatcher | Noe Ramirez | None | |
| 2018-03-30 | Fri | OAK | AL | A | N | 2 | W | 2-1 | 9 | box - pbp - pit | W1 | 1-1 | 2 | 10 | 11 | 2:48 | 27,665 | Tyler Skaggs | Sean Manaea (L) | Tyler Skaggs | Sean Manaea | Blake Parker | |
| 2018-03-31 | Sat | OAK | AL | A | D | 3 | W | 8-3 | 9 | box - pbp - pit | W2 | 2-1 | 1 | 2 | 8 | 3:23 | 17,012 | Matt Shoemaker | Daniel Mengden (R) | Matt Shoemaker | Daniel Mengden | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-04-01 | Sun | OAK | AL | A | D | 4 | W | 7-4 | 9 | box - pbp - pit | W3 | 3-1 | 1 | 2 | 5 | 3:07 | 14,644 | Shohei Ohtani | Daniel Gossett (R) | Shohei Ohtani | Daniel Gossett | Keynan Middleton | |
| 2018-04-02 | Mon | CLE | AL | H | N | 5 | L | 0-6 | 9 | box - pbp - pit | L1 | 3-2 | 3 | 5 | 11 | 3:25 | 43,904 | J.C. Ramirez | Mike Clevinger (R) | Mike Clevinger | J.C. Ramirez | None | |
| 2018-04-03 | Tue | CLE | AL | H | N | 6 | W | 13-2 | 9 | box - pbp - pit | W1 | 4-2 | 3 | 4 | 9 | 2:49 | 35,007 | Garrett Richards | Josh Tomlin (R) | Garrett Richards | Josh Tomlin | None | |
| 2018-04-04 | Wed | CLE | AL | H | D | 7 | W | 3-2 | 13 | box - pbp - pit | W2 | 5-2 | 2 | 3 | 6 | 4:28 | 32,412 | Tyler Skaggs | Corey Kluber (R) | Noe Ramirez | Zach McAllister | None | |
| 2018-04-06 | Fri | OAK | AL | H | N | 8 | W | 13-9 | 9 | box - pbp - pit | W3 | 6-2 | 1 | 2 | 5 | 3:35 | 36,023 | Parker Bridwell | Daniel Gossett (R) | Jim Johnson | Blake Treinen | None | |
| 2018-04-07 | Sat | OAK | AL | H | N | 9 | L | 3-7 | 9 | box - pbp - pit | L1 | 6-3 | 2 | 3 | 6 | 3:20 | 40,129 | J.C. Ramirez | Andrew Triggs (R) | Andrew Triggs | J.C. Ramirez | Blake Treinen | |
| 2018-04-08 | Sun | OAK | AL | H | D | 10 | W | 6-1 | 9 | box - pbp - pit | W1 | 7-3 | 2 | 3 | 6 | 2:53 | 44,742 | Shohei Ohtani | Kendall Graveman (R) | Shohei Ohtani | Kendall Graveman | None | |
| 2018-04-09 | Mon | TEX | AL | A | N | 11 | W | 8-3 | 9 | box - pbp - pit | W2 | 8-3 | 2 | 3 | 6 | 3:28 | 16,718 | Garrett Richards | Doug Fister (R) | Jose Alvarez | Doug Fister | None | |
| 2018-04-10 | Tue | TEX | AL | A | N | 12 | W | 11-1 | 9 | box - pbp - pit | W3 | 9-3 | 1 | 2 | 4 | 3:07 | 18,697 | Tyler Skaggs | Martin Perez (L) | Tyler Skaggs | Martin Perez | None | |
| 2018-04-11 | Wed | TEX | AL | A | N | 13 | W | 7-2 | 9 | box - pbp - pit | W4 | 10-3 | 1 | 2 | 3 | 3:27 | 20,363 | Jaime Barria | Matt Moore (L) | Jaime Barria | Matt Moore | Keynan Middleton | |
| 2018-04-12 | Thu | KCA | AL | A | N | 14 | W | 7-1 | 9 | box - pbp - pit | W5 | 11-3 | 1 | 2 | 3 | 3:00 | 14,714 | Nick Tropeano | Ian Kennedy (R) | Nick Tropeano | Ian Kennedy | None | |
| 2018-04-13 | Fri | KCA | AL | A | N | 15 | W | 5-4 | 9 | box - pbp - pit | W6 | 12-3 | 1 | 2 | 3 | 3:24 | 15,011 | Andrew Heaney | Jason Hammel (R) | Blake Wood | Justin Grimm | Keynan Middleton | |
| 2018-04-14 | Sat | KCA | AL | A | N | 16 | W | 5-3 | 9 | box - pbp - pit | W7 | 13-3 | 1 | 2 | 3 | 3:03 | 15,876 | Garrett Richards | Jake Junis (R) | Garrett Richards | Jake Junis | Keynan Middleton | |
| 2018-04-17 | Tue | BOS | AL | H | N | 17 | L | 1-10 | 9 | box - pbp - pit | L1 | 13-4 | 1 | 2 | 2 | 3:15 | 44,822 | Shohei Ohtani | David Price (L) | David Price | Shohei Ohtani | None | |
| 2018-04-18 | Wed | BOS | AL | H | N | 18 | L | 0-9 | 9 | box - pbp - pit | L2 | 13-5 | 1 | 2 | 3 | 3:18 | 34,508 | Tyler Skaggs | Rick Porcello (R) | Rick Porcello | Tyler Skaggs | None | |
| 2018-04-19 | Thu | BOS | AL | H | N | 19 | L | 2-8 | 9 | box - pbp - pit | L3 | 13-6 | 1 | 2 | 4 | 3:35 | 36,253 | Nick Tropeano | Eduardo Rodriguez (L) | Eduardo Rodriguez | Nick Tropeano | None | |
| 2018-04-20 | Fri | SFN | NL | H | N | 20 | L | 1-8 | 9 | box - pbp - pit | L4 | 13-7 | 2 | 4 | 6 | 2:50 | 37,494 | Andrew Heaney | Jeff Samardzija (R) | Jeff Samardzija | Andrew Heaney | None | |
| 2018-04-21 | Sat | SFN | NL | H | N | 21 | W | 4-3 | 9 | box - pbp - pit | W1 | 14-7 | 2 | 3 | 5 | 2:58 | 42,666 | Garrett Richards | Derek Holland (L) | Garrett Richards | Derek Holland | Keynan Middleton | |
| 2018-04-22 | Sun | SFN | NL | H | D | 22 | L | 2-4 | 9 | box - pbp - pit | L1 | 14-8 | 2 | 3 | 6 | 3:45 | 44,544 | Jaime Barria | Johnny Cueto (R) | Johnny Cueto | Jaime Barria | Hunter Strickland | |
| 2018-04-23 | Mon | HOU | AL | A | N | 23 | W | 2-0 | 9 | box - pbp - pit | W1 | 15-8 | 2 | 3 | 6 | 2:59 | 29,606 | Tyler Skaggs | Gerrit Cole (R) | Tyler Skaggs | Gerrit Cole | Keynan Middleton | |
| 2018-04-24 | Tue | HOU | AL | A | N | 24 | W | 8-7 | 9 | box - pbp - pit | W2 | 16-8 | 1 | 2 | 4 | 3:48 | 36,457 | Shohei Ohtani | Charlie Morton (R) | Jim Johnson | Joe Smith | Cam Bedrosian | |
| 2018-04-25 | Wed | HOU | AL | A | D | 25 | L | 2-5 | 9 | box - pbp - pit | L1 | 16-9 | 2 | 3 | 6 | 2:44 | 29,777 | Nick Tropeano | Justin Verlander (R) | Justin Verlander | Nick Tropeano | Ken Giles | |
| 2018-04-27 | Fri | NYA | AL | H | N | 26 | L | 3-4 | 10 | box - pbp - pit | L2 | 16-10 | 2 | 4 | 7 | 3:15 | 40,416 | Andrew Heaney | Luis Severino (R) | David Robertson | Blake Parker | Aroldis Chapman | |
| 2018-04-28 | Sat | NYA | AL | H | N | 27 | L | 1-11 | 9 | box - pbp - pit | L3 | 16-11 | 2 | 4 | 7 | 3:09 | 44,649 | Garrett Richards | Masahiro Tanaka (R) | Masahiro Tanaka | Garrett Richards | None | |
| 2018-04-29 | Sun | NYA | AL | H | N | 28 | L | 1-2 | 9 | box - pbp - pit | L4 | 16-12 | 3 | 5 | 11 | 3:00 | 44,593 | Tyler Skaggs | CC Sabathia (L) | CC Sabathia | Tyler Skaggs | Aroldis Chapman | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-05-01 | Tue | BAL | AL | H | N | 29 | W | 3-2 | 9 | box - pbp - pit | W1 | 17-12 | 3 | 5 | 10 | 2:58 | 32,345 | Nick Tropeano | Alex Cobb (R) | Cam Bedrosian | Brad Brach | None | |
| 2018-05-02 | Wed | BAL | AL | H | N | 30 | W | 10-7 | 9 | box - pbp - pit | W2 | 18-12 | 2 | 4 | 7 | 3:14 | 32,156 | Andrew Heaney | Dylan Bundy (R) | Andrew Heaney | Dylan Bundy | None | |
| 2018-05-03 | Thu | BAL | AL | H | N | 31 | W | 12-3 | 9 | box - pbp - pit | W3 | 19-12 | 1 | 3 | 5 | 3:02 | 35,879 | Jaime Barria | Chris Tillman (R) | Jaime Barria | Chris Tillman | None | |
| 2018-05-04 | Fri | SEA | AL | A | N | 32 | W | 5-0 | 9 | box - pbp - pit | W4 | 20-12 | 1 | 3 | 4 | 3:10 | 41,705 | Garrett Richards | Mike Leake (R) | Garrett Richards | Mike Leake | None | |
| 2018-05-05 | Sat | SEA | AL | A | N | 33 | L | 8-9 | 11 | box - pbp - pit | L1 | 20-13 | 1 | 3 | 5 | 4:29 | 36,977 | Tyler Skaggs | Marco Gonzales (L) | Erik Goeddel | Jim Johnson | None | |
| 2018-05-06 | Sun | SEA | AL | A | D | 34 | W | 8-2 | 9 | box - pbp - pit | W1 | 21-13 | 1 | 3 | 5 | 3:11 | 40,142 | Shohei Ohtani | Felix Hernandez (R) | Shohei Ohtani | Felix Hernandez | None | |
| 2018-05-08 | Tue | COL | NL | A | N | 35 | L | 2-4 | 9 | box - pbp - pit | L1 | 21-14 | 2 | 4 | 5 | 2:42 | 33,144 | Andrew Heaney | Jon Gray (R) | Jon Gray | Andrew Heaney | Wade Davis | |
| 2018-05-09 | Wed | COL | NL | A | D | 36 | W | 8-0 | 9 | box - pbp - pit | W1 | 22-14 | 2 | 4 | 5 | 3:10 | 33,689 | Jaime Barria | Tyler Anderson (L) | Jaime Barria | Tyler Anderson | None | |
| 2018-05-10 | Thu | MIN | AL | H | N | 37 | W | 7-4 | 9 | box - pbp - pit | W2 | 23-14 | 1 | 3 | 4 | 3:08 | 30,127 | Garrett Richards | Jose Berrios (R) | Jose Alvarez | Jose Berrios | Jim Johnson | |
| 2018-05-11 | Fri | MIN | AL | H | N | 38 | L | 4-5 | 9 | box - pbp - pit | L1 | 23-15 | 1 | 3 | 5 | 3:23 | 43,521 | Tyler Skaggs | Lance Lynn (R) | Matt Magill | Justin Anderson | Fernando Rodney | |
| 2018-05-12 | Sat | MIN | AL | H | N | 39 | L | 3-5 | 12 | box - pbp - pit | L2 | 23-16 | 2 | 4 | 8 | 4:21 | 40,117 | Nick Tropeano | Kyle Gibson (R) | Trevor Hildenberger | Noe Ramirez | Fernando Rodney | |
| 2018-05-13 | Sun | MIN | AL | H | D | 40 | W | 2-1 | 9 | box - pbp - pit | W1 | 24-16 | 2 | 4 | 5 | 3:28 | 38,029 | Shohei Ohtani | Fernando Romero (R) | Blake Parker | Zach Duke | None | |
| 2018-05-14 | Mon | HOU | AL | H | N | 41 | W | 2-1 | 9 | box - pbp - pit | W2 | 25-16 | 1 | 3 | 4 | 2:27 | 28,229 | Andrew Heaney | Lance McCullers (R) | Andrew Heaney | Lance McCullers | Justin Anderson | |
| 2018-05-15 | Tue | HOU | AL | H | N | 42 | L | 3-5 | 9 | box - pbp - pit | L1 | 25-17 | 2 | 4 | 5 | 3:18 | 28,358 | Jaime Barria | Gerrit Cole (R) | Collin McHugh | Jose Alvarez | Ken Giles | |
| 2018-05-16 | Wed | HOU | AL | H | N | 43 | L | 0-2 | 9 | box - pbp - pit | L2 | 25-18 | 2 | 4 | 8 | 2:39 | 28,078 | Garrett Richards | Justin Verlander (R) | Justin Verlander | Garrett Richards | None | |
| 2018-05-17 | Thu | TBA | AL | H | N | 44 | L | 1-7 | 9 | box - pbp - pit | L3 | 25-19 | 2 | 4 | 10 | 3:06 | 30,487 | Tyler Skaggs | Chris Archer (R) | Chris Archer | Tyler Skaggs | None | |
| 2018-05-18 | Fri | TBA | AL | H | N | 45 | L | 3-8 | 9 | box - pbp - pit | L4 | 25-20 | 3 | 5 | 13 | 3:32 | 40,067 | Nick Tropeano | Blake Snell (L) | Blake Snell | Nick Tropeano | None | |
| 2018-05-19 | Sat | TBA | AL | H | N | 46 | L | 3-5 | 9 | box - pbp - pit | L5 | 25-21 | 3 | 5 | 13 | 3:00 | 37,232 | Andrew Heaney | Sergio Romo (R) | Ryan Yarbrough | Andrew Heaney | Alex Colome | |
| 2018-05-20 | Sun | TBA | AL | H | D | 47 | W | 5-2 | 9 | box - pbp - pit | W1 | 26-21 | 3 | 5 | 11 | 3:15 | 38,560 | Shohei Ohtani | Sergio Romo (R) | Shohei Ohtani | Matt Andriese | Blake Parker | |
| 2018-05-22 | Tue | TOR | AL | A | N | 48 | L | 3-5 | 9 | box - pbp - pit | L1 | 26-22 | 3 | 5 | 13 | 2:31 | 21,480 | Garrett Richards | J.A. Happ (L) | J.A. Happ | Garrett Richards | Tyler Clippard | |
| 2018-05-23 | Wed | TOR | AL | A | N | 49 | W | 5-4 | 9 | box - pbp - pit | W1 | 27-22 | 3 | 5 | 10 | 3:45 | 25,504 | Tyler Skaggs | Aaron Sanchez (R) | Justin Anderson | Tyler Clippard | Blake Parker | |
| 2018-05-24 | Thu | TOR | AL | A | D | 50 | W | 8-1 | 9 | box - pbp - pit | W2 | 28-22 | 3 | 5 | 8 | 2:53 | 43,344 | Nick Tropeano | Marco Estrada (R) | Nick Tropeano | Marco Estrada | None | |
| 2018-05-25 | Fri | NYA | AL | A | N | 51 | L | 1-2 | 9 | box - pbp - pit | L1 | 28-23 | 3 | 5 | 11 | 3:00 | 46,056 | Andrew Heaney | Luis Severino (R) | Chad Green | Jim Johnson | Aroldis Chapman | |
| 2018-05-26 | Sat | NYA | AL | A | N | 52 | W | 11-4 | 9 | box - pbp - pit | W1 | 29-23 | 3 | 5 | 9 | 3:30 | 44,565 | Jaime Barria | Sonny Gray (R) | Jaime Barria | Sonny Gray | None | |
| 2018-05-27 | Sun | NYA | AL | A | D | 53 | L | 1-3 | 9 | box - pbp - pit | L1 | 29-24 | 3 | 5 | 11 | 3:27 | 46,109 | Garrett Richards | Masahiro Tanaka (R) | Masahiro Tanaka | Garrett Richards | Aroldis Chapman | |
| 2018-05-28 | Mon | DET | AL | A | D | 54 | L | 3-9 | 9 | box - pbp - pit | L2 | 29-25 | 3 | 5 | 11 | 3:17 | 20,857 | Tyler Skaggs | Matt Boyd (L) | Matt Boyd | Tyler Skaggs | None | |
| 2018-05-29 | Tue | DET | AL | A | N | 55 | W | 9-2 | 9 | box - pbp - pit | W1 | 30-25 | 3 | 5 | 11 | 3:25 | 17,397 | Nick Tropeano | Michael Fulmer (R) | Nick Tropeano | Michael Fulmer | None | |
| 2018-05-30 | Wed | DET | AL | A | N | 56 | L | 1-6 | 9 | box - pbp - pit | L1 | 30-26 | 3 | 6 | 12 | 2:53 | 19,494 | Shohei Ohtani | Mike Fiers (R) | Louis Coleman | Cam Bedrosian | None | |
| 2018-05-31 | Thu | DET | AL | A | D | 57 | L | 2-6 | 9 | box - pbp - pit | L2 | 30-27 | 3 | 6 | 13 | 3:09 | 24,696 | Andrew Heaney | Ryan Carpenter (L) | Warwick Saupold | Andrew Heaney | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-06-01 | Fri | TEX | AL | H | N | 58 | W | 6-0 | 9 | box - pbp - pit | W1 | 31-27 | 3 | 6 | 12 | 2:37 | 33,511 | Jaime Barria | Bartolo Colon (R) | Jaime Barria | Bartolo Colon | None | |
| 2018-06-02 | Sat | TEX | AL | H | N | 59 | L | 2-3 | 10 | box - pbp - pit | L1 | 31-28 | 3 | 6 | 13 | 3:21 | 44,603 | Garrett Richards | Cole Hamels (L) | Jake Diekman | Jose Alvarez | Keone Kela | |
| 2018-06-03 | Sun | TEX | AL | H | D | 60 | W | 3-1 | 9 | box - pbp - pit | W1 | 32-28 | 3 | 5 | 12 | 2:39 | 33,541 | Tyler Skaggs | Doug Fister (R) | Tyler Skaggs | Doug Fister | Justin Anderson | |
| 2018-06-04 | Mon | KCA | AL | H | N | 61 | W | 9-6 | 9 | box - pbp - pit | W2 | 33-28 | 3 | 5 | 11 | 3:35 | 32,553 | Nick Tropeano | Danny Duffy (L) | Cam Bedrosian | Tim Hill | Blake Parker | |
| 2018-06-05 | Tue | KCA | AL | H | N | 62 | W | 1-0 | 9 | box - pbp - pit | W3 | 34-28 | 3 | 5 | 11 | 2:16 | 31,514 | Andrew Heaney | Brad Keller (R) | Andrew Heaney | Brad Keller | None | |
| 2018-06-06 | Wed | KCA | AL | H | N | 63 | W | 4-3 | 9 | box - pbp - pit | W4 | 35-28 | 3 | 5 | 9 | 3:11 | 36,512 | Shohei Ohtani | Ian Kennedy (R) | Cam Bedrosian | Scott Barlow | Blake Parker | |
| 2018-06-08 | Fri | MIN | AL | A | N | 64 | W | 4-2 | 9 | box - pbp - pit | W5 | 36-28 | 3 | 5 | 9 | 3:21 | 28,383 | Garrett Richards | Lance Lynn (R) | Noe Ramirez | Ryan Pressly | Blake Parker | |
| 2018-06-09 | Sat | MIN | AL | A | N | 65 | W | 2-1 | 9 | box - pbp - pit | W6 | 37-28 | 3 | 5 | 9 | 2:53 | 24,061 | Tyler Skaggs | Kyle Gibson (R) | Tyler Skaggs | Kyle Gibson | Blake Parker | |
| 2018-06-10 | Sun | MIN | AL | A | D | 66 | L | 5-7 | 9 | box - pbp - pit | L1 | 37-29 | 3 | 5 | 9 | 3:08 | 28,656 | Nick Tropeano | Fernando Romero (R) | Fernando Romero | Nick Tropeano | None | |
| 2018-06-11 | Mon | SEA | AL | A | N | 67 | L | 3-5 | 9 | box - pbp - pit | L2 | 37-30 | 3 | 5 | 11 | 2:35 | 20,116 | Andrew Heaney | Wade LeBlanc (L) | Wade LeBlanc | Andrew Heaney | Edwin Diaz | |
| 2018-06-12 | Tue | SEA | AL | A | N | 68 | L | 3-6 | 9 | box - pbp - pit | L3 | 37-31 | 3 | 5 | 11 | 3:01 | 20,402 | Jaime Barria | Mike Leake (R) | Mike Leake | Jaime Barria | Edwin Diaz | |
| 2018-06-13 | Wed | SEA | AL | A | D | 69 | L | 6-8 | 9 | box - pbp - pit | L4 | 37-32 | 3 | 5 | 11 | 3:35 | 28,236 | Garrett Richards | Marco Gonzales (L) | Roenis Elias | Oliver Drake | None | |
| 2018-06-15 | Fri | OAK | AL | A | N | 70 | W | 8-4 | 9 | box - pbp - pit | W1 | 38-32 | 3 | 5 | 10 | 3:22 | 18,356 | Tyler Skaggs | Chris Bassitt (R) | Tyler Skaggs | Chris Bassitt | None | |
| 2018-06-16 | Sat | OAK | AL | A | D | 71 | L | 4-6 | 9 | box - pbp - pit | L1 | 38-33 | 3 | 5 | 11 | 2:42 | 19,185 | John Lamb | Sean Manaea (L) | Sean Manaea | Noe Ramirez | Blake Treinen | |
| 2018-06-17 | Sun | OAK | AL | A | D | 72 | L | 5-6 | 11 | box - pbp - pit | L2 | 38-34 | 3 | 6 | 14 | 3:38 | 21,217 | Andrew Heaney | Daniel Mengden (R) | Blake Treinen | Jake Jewell | None | |
| 2018-06-18 | Mon | ARI | NL | H | N | 73 | L | 4-7 | 9 | box - pbp - pit | L3 | 38-35 | 3 | 6 | 14 | 3:21 | 33,809 | Jaime Barria | Zack Greinke (R) | Zack Greinke | Jaime Barria | Archie Bradley | |
| 2018-06-19 | Tue | ARI | NL | H | N | 74 | W | 5-4 | 9 | box - pbp - pit | W1 | 39-35 | 3 | 6 | 14 | 3:11 | 33,088 | Felix Pena | Matt Koch (R) | Jose Alvarez | Matt Koch | Blake Parker | |
| 2018-06-21 | Thu | TOR | AL | H | N | 75 | W | 8-5 | 9 | box - pbp - pit | W2 | 40-35 | 3 | 6 | 12 | 3:03 | 30,416 | John Lamb | Aaron Sanchez (R) | Noe Ramirez | John Axford | Justin Anderson | |
| 2018-06-22 | Fri | TOR | AL | H | N | 76 | W | 2-1 | 9 | box - pbp - pit | W3 | 41-35 | 3 | 6 | 12 | 2:17 | 38,028 | Andrew Heaney | Marco Estrada (R) | Andrew Heaney | Marco Estrada | Blake Parker | |
| 2018-06-23 | Sat | TOR | AL | H | N | 77 | L | 1-4 | 9 | box - pbp - pit | L1 | 41-36 | 3 | 6 | 13 | 3:07 | 40,612 | Jaime Barria | Marcus Stroman (R) | Seung Hwan Oh | Justin Anderson | Ryan Tepera | |
| 2018-06-24 | Sun | TOR | AL | H | D | 78 | L | 6-7 | 10 | box - pbp - pit | L2 | 41-37 | 3 | 6 | 14 | 3:33 | 33,102 | Felix Pena | Sam Gaviglio (R) | Ryan Tepera | Hansel Robles | Tyler Clippard | |
| 2018-06-25 | Mon | KCA | AL | A | D | 79 | L | 0-2 | 9 | box - pbp - pit | L3 | 41-38 | 3 | 6 | 14 | 2:44 | 19,535 | Tyler Skaggs | Brad Keller (R) | Brad Keller | Tyler Skaggs | Wily Peralta | |
| 2018-06-26 | Tue | BOS | AL | A | N | 80 | L | 1-9 | 9 | box - pbp - pit | L4 | 41-39 | 4 | 7 | 15 | 2:54 | 37,366 | John Lamb | David Price (L) | David Price | John Lamb | None | |
| 2018-06-27 | Wed | BOS | AL | A | N | 81 | L | 6-9 | 9 | box - pbp - pit | L5 | 41-40 | 4 | 7 | 16 | 4:00 | 37,521 | Andrew Heaney | Rick Porcello (R) | Matt Barnes | Jose Alvarez | Craig Kimbrel | |
| 2018-06-28 | Thu | BOS | AL | A | N | 82 | L | 2-4 | 9 | box - pbp - pit | L6 | 41-41 | 4 | 7 | 16 | 3:06 | 36,992 | Jaime Barria | Brian Johnson (L) | Hector Velazquez | Jaime Barria | Craig Kimbrel | |
| 2018-06-29 | Fri | BAL | AL | A | N | 83 | W | 7-1 | 9 | box - pbp - pit | W1 | 42-41 | 4 | 7 | 16 | 2:53 | 24,007 | Felix Pena | David Hess (R) | Felix Pena | David Hess | None | |
| 2018-06-30 | Sat | BAL | AL | A | D | 84 | W | 6-2 | 9 | box - pbp - pit | W2 | 43-41 | 4 | 7 | 16 | 3:09 | 38,838 | Tyler Skaggs | Andrew Cashner (R) | Justin Anderson | Mychal Givens | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-07-01 | Sun | BAL | AL | A | D | 85 | L | 2-8 | 9 | box - pbp - pit | L1 | 43-42 | 4 | 8 | 17 | 2:29 | 18,351 | Deck McGuire | Kevin Gausman (R) | Kevin Gausman | Deck McGuire | None | |
| 2018-07-03 | Tue | SEA | AL | A | N | 86 | L | 1-4 | 9 | box - pbp - pit | L2 | 43-43 | 4 | 8 | 16 | 2:27 | 38,624 | Andrew Heaney | Wade LeBlanc (L) | Wade LeBlanc | Andrew Heaney | Edwin Diaz | |
| 2018-07-04 | Wed | SEA | AL | A | D | 87 | W | 7-4 | 9 | box - pbp - pit | W1 | 44-43 | 4 | 7 | 15 | 3:33 | 39,518 | Garrett Richards | Mike Leake (R) | Garrett Richards | Mike Leake | Blake Parker | |
| 2018-07-05 | Thu | SEA | AL | A | N | 88 | L | 1-4 | 9 | box - pbp - pit | L1 | 44-44 | 4 | 7 | 17 | 3:22 | 32,128 | Jaime Barria | Marco Gonzales (L) | Marco Gonzales | Jaime Barria | Edwin Diaz | |
| 2018-07-06 | Fri | LAN | NL | H | N | 89 | W | 3-2 | 9 | box - pbp - pit | W1 | 45-44 | 4 | 7 | 17 | 3:12 | 44,323 | Felix Pena | Kenta Maeda (R) | Blake Parker | Kenley Jansen | None | |
| 2018-07-07 | Sat | LAN | NL | H | D | 90 | L | 1-3 | 9 | box - pbp - pit | L1 | 45-45 | 4 | 7 | 17 | 3:18 | 44,409 | Deck McGuire | Ross Stripling (R) | Ross Stripling | Taylor Cole | Kenley Jansen | |
| 2018-07-08 | Sun | LAN | NL | H | N | 91 | W | 4-3 | 9 | box - pbp - pit | W1 | 46-45 | 4 | 8 | 18 | 2:39 | 42,213 | Andrew Heaney | Alex Wood (L) | Andrew Heaney | J.T. Chargois | Justin Anderson | |
| 2018-07-10 | Tue | SEA | AL | H | N | 92 | W | 9-3 | 9 | box - pbp - pit | W2 | 47-45 | 4 | 8 | 15 | 3:10 | 33,092 | Garrett Richards | Mike Leake (R) | Noe Ramirez | Mike Leake | None | |
| 2018-07-11 | Wed | SEA | AL | H | N | 93 | L | 0-3 | 9 | box - pbp - pit | L1 | 47-46 | 4 | 8 | 17 | 2:40 | 35,591 | Jaime Barria | Marco Gonzales (L) | Marco Gonzales | Jaime Barria | Edwin Diaz | |
| 2018-07-12 | Thu | SEA | AL | H | N | 94 | W | 11-2 | 9 | box - pbp - pit | W1 | 48-46 | 4 | 8 | 17 | 3:02 | 44,027 | Tyler Skaggs | James Paxton (L) | Tyler Skaggs | James Paxton | None | |
| 2018-07-13 | Fri | LAN | NL | A | N | 95 | L | 2-3 | 9 | box - pbp - pit | L1 | 48-47 | 4 | 8 | 17 | 3:13 | 53,368 | Felix Pena | Walker Buehler (R) | Caleb Ferguson | Cam Bedrosian | Scott Alexander | |
| 2018-07-14 | Sat | LAN | NL | A | D | 96 | W | 5-4 | 10 | box - pbp - pit | W1 | 49-47 | 4 | 8 | 16 | 3:47 | 53,797 | Andrew Heaney | Alex Wood (L) | Jose Alvarez | Kenley Jansen | None | |
| 2018-07-15 | Sun | LAN | NL | A | D | 97 | L | 3-5 | 9 | box - pbp - pit | L1 | 49-48 | 4 | 8 | 17 | 3:10 | 47,871 | Deck McGuire | Clayton Kershaw (L) | Kenta Maeda | Taylor Cole | Kenley Jansen | |
| 2018-07-20 | Fri | HOU | AL | H | N | 98 | L | 1-3 | 9 | box - pbp - pit | L2 | 49-49 | 4 | 8 | 18 | 2:47 | 42,422 | Tyler Skaggs | Dallas Keuchel (L) | Dallas Keuchel | Tyler Skaggs | Hector Rondon | |
| 2018-07-21 | Sat | HOU | AL | H | D | 99 | L | 0-7 | 9 | box - pbp - pit | L3 | 49-50 | 4 | 8 | 18 | 3:20 | 44,264 | Nick Tropeano | Justin Verlander (R) | Justin Verlander | Nick Tropeano | None | |
| 2018-07-22 | Sun | HOU | AL | H | D | 100 | W | 14-5 | 9 | box - pbp - pit | W1 | 50-50 | 4 | 8 | 19 | 3:41 | 35,298 | Andrew Heaney | Lance McCullers (R) | Andrew Heaney | Lance McCullers | None | |
| 2018-07-23 | Mon | CHA | AL | H | N | 101 | L | 3-5 | 9 | box - pbp - pit | L1 | 50-51 | 4 | 8 | 18 | 3:36 | 35,285 | Jaime Barria | Lucas Giolito (R) | Lucas Giolito | Jaime Barria | Joakim Soria | |
| 2018-07-24 | Tue | CHA | AL | H | N | 102 | L | 2-4 | 9 | box - pbp - pit | L2 | 50-52 | 4 | 8 | 18 | 2:58 | 33,937 | Felix Pena | Carlos Rodon (L) | Carlos Rodon | Felix Pena | Joakim Soria | |
| 2018-07-25 | Wed | CHA | AL | H | N | 103 | W | 11-3 | 9 | box - pbp - pit | W1 | 51-52 | 4 | 8 | 18 | 3:03 | 34,321 | Tyler Skaggs | James Shields (R) | Tyler Skaggs | James Shields | None | |
| 2018-07-26 | Thu | CHA | AL | H | D | 104 | W | 12-8 | 9 | box - pbp - pit | W2 | 52-52 | 4 | 8 | 19 | 3:29 | 33,826 | Nick Tropeano | Dylan Covey (R) | Nick Tropeano | Dylan Covey | None | |
| 2018-07-27 | Fri | SEA | AL | H | N | 105 | W | 4-3 | 10 | box - pbp - pit | W3 | 53-52 | 4 | 8 | 18 | 2:54 | 42,336 | Andrew Heaney | Wade LeBlanc (L) | Jim Johnson | Juan Nicasio | None | |
| 2018-07-28 | Sat | SEA | AL | H | N | 106 | W | 11-5 | 9 | box - pbp - pit | W4 | 54-52 | 4 | 7 | 16 | 2:41 | 43,325 | Jaime Barria | Felix Hernandez (R) | Jaime Barria | Felix Hernandez | None | |
| 2018-07-29 | Sun | SEA | AL | H | D | 107 | L | 5-8 | 9 | box - pbp - pit | L1 | 54-53 | 4 | 7 | 16 | 3:32 | 35,396 | Felix Pena | Marco Gonzales (L) | Marco Gonzales | Felix Pena | Edwin Diaz | |
| 2018-07-31 | Tue | TBA | AL | A | N | 108 | L | 6-10 | 9 | box - pbp - pit | L2 | 54-54 | 4 | 8 | 19 | 3:17 | 15,858 | Tyler Skaggs | Ryne Stanek (R) | Ryan Yarbrough | Tyler Skaggs | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-08-01 | Wed | TBA | AL | A | N | 109 | L | 2-7 | 9 | box - pbp - pit | L3 | 54-55 | 4 | 8 | 19 | 3:01 | 9,132 | Nick Tropeano | Tyler Glasnow (R) | Jacob Faria | Nick Tropeano | None | |
| 2018-08-02 | Thu | TBA | AL | A | D | 110 | L | 2-4 | 9 | box - pbp - pit | L4 | 54-56 | 4 | 8 | 19 | 2:29 | 10,988 | Andrew Heaney | Hunter Wood (R) | Jalen Beeks | Andrew Heaney | Sergio Romo | |
| 2018-08-03 | Fri | CLE | AL | A | N | 111 | W | 7-4 | 9 | box - pbp - pit | W1 | 55-56 | 4 | 8 | 19 | 3:10 | 35,242 | Jaime Barria | Mike Clevinger (R) | Justin Anderson | Oliver Perez | None | |
| 2018-08-04 | Sat | CLE | AL | A | N | 112 | L | 0-3 | 9 | box - pbp - pit | L1 | 55-57 | 4 | 8 | 19 | 2:28 | 34,814 | Felix Pena | Corey Kluber (R) | Corey Kluber | Felix Pena | None | |
| 2018-08-05 | Sun | CLE | AL | A | D | 113 | L | 3-4 | 9 | box - pbp - pit | L2 | 55-58 | 4 | 8 | 19 | 3:06 | 28,993 | Deck McGuire | Shane Bieber (R) | Shane Bieber | Deck McGuire | Brad Hand | |
| 2018-08-06 | Mon | DET | AL | H | N | 114 | W | 6-2 | 9 | box - pbp - pit | W1 | 56-58 | 4 | 8 | 19 | 2:53 | 34,073 | Nick Tropeano | Matt Boyd (L) | Nick Tropeano | Matt Boyd | None | |
| 2018-08-07 | Tue | DET | AL | H | N | 115 | W | 11-5 | 9 | box - pbp - pit | W2 | 57-58 | 4 | 8 | 18 | 3:08 | 35,824 | Andrew Heaney | Jacob Turner (R) | Andrew Heaney | Jacob Turner | None | |
| 2018-08-08 | Wed | DET | AL | H | D | 116 | W | 6-0 | 9 | box - pbp - pit | W3 | 58-58 | 4 | 8 | 18 | 2:45 | 38,832 | Jaime Barria | Blaine Hardy (L) | Jaime Barria | Blaine Hardy | None | |
| 2018-08-10 | Fri | OAK | AL | H | N | 117 | W | 4-3 | 9 | box - pbp - pit | W4 | 59-58 | 4 | 8 | 18 | 2:22 | 42,722 | Felix Pena | Brett Anderson (L) | Jim Johnson | Lou Trivino | Blake Parker | |
| 2018-08-11 | Sat | OAK | AL | H | N | 118 | L | 0-7 | 9 | box - pbp - pit | L1 | 59-59 | 4 | 8 | 18 | 3:08 | 39,425 | Tyler Skaggs | Edwin Jackson (R) | Edwin Jackson | Tyler Skaggs | None | |
| 2018-08-12 | Sun | OAK | AL | H | D | 119 | L | 7-8 | 9 | box - pbp - pit | L2 | 59-60 | 4 | 8 | 18 | 3:49 | 38,364 | Taylor Cole | Trevor Cahill (R) | Fernando Rodney | Jim Johnson | Blake Treinen | |
| 2018-08-13 | Mon | SDN | NL | A | N | 120 | W | 6-3 | 10 | box - pbp - pit | W1 | 60-60 | 4 | 8 | 18 | 2:47 | 22,609 | Andrew Heaney | Clayton Richard (L) | Cam Bedrosian | Craig Stammen | None | |
| 2018-08-14 | Tue | SDN | NL | A | N | 121 | W | 7-3 | 9 | box - pbp - pit | W2 | 61-60 | 4 | 8 | 18 | 3:14 | 21,747 | Jaime Barria | Brett Kennedy (R) | Jaime Barria | Brett Kennedy | None | |
| 2018-08-15 | Wed | SDN | NL | A | N | 122 | W | 3-2 | 9 | box - pbp - pit | W3 | 62-60 | 4 | 8 | 16 | 2:43 | 22,851 | Felix Pena | Robbie Erlin (L) | Jose Alvarez | Kirby Yates | Blake Parker | |
| 2018-08-16 | Thu | TEX | AL | A | N | 123 | L | 6-8 | 9 | box - pbp - pit | L1 | 62-61 | 4 | 8 | 16 | 2:53 | 18,398 | Taylor Cole | Ariel Jurado (R) | Matt Moore | Justin Anderson | Jose Leclerc | |
| 2018-08-17 | Fri | TEX | AL | A | N | 124 | L | 4-6 | 9 | box - pbp - pit | L2 | 62-62 | 4 | 8 | 17 | 2:56 | 27,816 | Odrisamer Despaigne | Drew Hutchison (R) | Drew Hutchison | Odrisamer Despaigne | Jose Leclerc | |
| 2018-08-18 | Sat | TEX | AL | A | N | 125 | W | 11-7 | 9 | box - pbp - pit | W1 | 63-62 | 4 | 8 | 16 | 3:28 | 24,768 | Andrew Heaney | Martin Perez (L) | Cam Bedrosian | Eddie Butler | None | |
| 2018-08-19 | Sun | TEX | AL | A | D | 126 | L | 2-4 | 9 | box - pbp - pit | L1 | 63-63 | 4 | 8 | 17 | 2:35 | 26,681 | Jaime Barria | Yovani Gallardo (R) | Matt Moore | Noe Ramirez | Jose Leclerc | |
| 2018-08-21 | Tue | ARI | NL | A | N | 127 | L | 4-5 | 9 | box - pbp - pit | L2 | 63-64 | 4 | 8 | 17 | 2:54 | 30,420 | Felix Pena | Patrick Corbin (L) | Brad Boxberger | Cam Bedrosian | None | |
| 2018-08-22 | Wed | ARI | NL | A | N | 128 | L | 1-5 | 9 | box - pbp - pit | L3 | 63-65 | 4 | 8 | 17 | 3:05 | 23,584 | Odrisamer Despaigne | Clay Buchholz (R) | Clay Buchholz | Odrisamer Despaigne | None | |
| 2018-08-24 | Fri | HOU | AL | H | N | 129 | L | 3-9 | 9 | box - pbp - pit | L4 | 63-66 | 4 | 8 | 17 | 3:04 | 42,788 | Andrew Heaney | Dallas Keuchel (L) | Dallas Keuchel | Andrew Heaney | None | |
| 2018-08-25 | Sat | HOU | AL | H | N | 130 | L | 3-8 | 9 | box - pbp - pit | L5 | 63-67 | 4 | 8 | 19 | 3:26 | 41,654 | Jaime Barria | Justin Verlander (R) | Justin Verlander | Jaime Barria | None | |
| 2018-08-26 | Sun | HOU | AL | H | D | 131 | L | 1-3 | 9 | box - pbp - pit | L6 | 63-68 | 4 | 8 | 19 | 2:54 | 37,530 | Felix Pena | Framber Valdez (L) | Framber Valdez | Felix Pena | Roberto Osuna | |
| 2018-08-27 | Mon | COL | NL | H | N | 132 | W | 10-7 | 9 | box - pbp - pit | W1 | 64-68 | 4 | 8 | 19 | 3:37 | 35,305 | Odrisamer Despaigne | Jon Gray (R) | Jim Johnson | Adam Ottavino | Noe Ramirez | |
| 2018-08-28 | Tue | COL | NL | H | N | 133 | L | 2-3 | 9 | box - pbp - pit | L1 | 64-69 | 4 | 8 | 19 | 2:59 | 35,207 | Noe Ramirez | Kyle Freeland (L) | Kyle Freeland | Noe Ramirez | Wade Davis | |
| 2018-08-30 | Thu | HOU | AL | A | N | 134 | W | 5-2 | 9 | box - pbp - pit | W1 | 65-69 | 4 | 8 | 19 | 3:20 | 30,371 | Andrew Heaney | Justin Verlander (R) | Andrew Heaney | Justin Verlander | None | |
| 2018-08-31 | Fri | HOU | AL | A | N | 135 | W | 3-0 | 9 | box - pbp - pit | W2 | 66-69 | 4 | 8 | 18 | 3:18 | 35,675 | Jaime Barria | Framber Valdez (L) | Jaime Barria | Framber Valdez | Blake Parker | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2018-09-01 | Sat | HOU | AL | A | N | 136 | L | 3-7 | 9 | box - pbp - pit | L1 | 66-70 | 4 | 8 | 18 | 3:16 | 41,622 | Felix Pena | Joshua James (R) | Joe Smith | Cam Bedrosian | None | |
| 2018-09-02 | Sun | HOU | AL | A | N | 137 | L | 2-4 | 9 | box - pbp - pit | L2 | 66-71 | 4 | 8 | 18 | 3:40 | 41,506 | Shohei Ohtani | Gerrit Cole (R) | Gerrit Cole | Shohei Ohtani | Roberto Osuna | |
| 2018-09-03 | Mon | TEX | AL | A | N | 138 | W | 3-1 | 9 | box - pbp - pit | W1 | 67-71 | 4 | 8 | 18 | 3:10 | 21,048 | Matt Shoemaker | Jeffrey Springs (L) | Taylor Cole | Zac Curtis | Blake Parker | |
| 2018-09-04 | Tue | TEX | AL | A | N | 139 | L | 2-4 | 9 | box - pbp - pit | L1 | 67-72 | 4 | 8 | 19 | 2:44 | 17,625 | Andrew Heaney | Mike Minor (L) | Mike Minor | Andrew Heaney | Jose Leclerc | |
| 2018-09-05 | Wed | TEX | AL | A | N | 140 | W | 9-3 | 9 | box - pbp - pit | W1 | 68-72 | 4 | 8 | 18 | 3:12 | 19,966 | Jaime Barria | Bartolo Colon (R) | Jaime Barria | Bartolo Colon | None | |
| 2018-09-07 | Fri | CHA | AL | A | N | 141 | W | 5-2 | 9 | box - pbp - pit | W2 | 69-72 | 4 | 8 | 17 | 2:55 | 18,236 | Felix Pena | Carlos Rodon (L) | Felix Pena | Carlos Rodon | Ty Buttrey | |
| 2018-09-08 | Sat | CHA | AL | A | N | 142 | W | 12-3 | 9 | box - pbp - pit | W3 | 70-72 | 4 | 8 | 18 | 3:45 | 27,146 | Matt Shoemaker | James Shields (R) | Matt Shoemaker | James Shields | None | |
| 2018-09-09 | Sun | CHA | AL | A | D | 143 | W | 1-0 | 9 | box - pbp - pit | W4 | 71-72 | 4 | 8 | 17 | 3:17 | 24,020 | Andrew Heaney | Reynaldo Lopez (R) | Andrew Heaney | Ian Hamilton | Jose Alvarez | |
| 2018-09-10 | Mon | TEX | AL | H | N | 144 | L | 2-5 | 9 | box - pbp - pit | L1 | 71-73 | 4 | 8 | 17 | 3:10 | 32,891 | Jaime Barria | Mike Minor (L) | Mike Minor | Jaime Barria | Jose Leclerc | |
| 2018-09-11 | Tue | TEX | AL | H | N | 145 | W | 1-0 | 9 | box - pbp - pit | W1 | 72-73 | 4 | 8 | 17 | 2:45 | 33,756 | Jim Johnson | Adrian Sampson (R) | Noe Ramirez | Adrian Sampson | Ty Buttrey | |
| 2018-09-12 | Wed | TEX | AL | H | N | 146 | W | 8-1 | 9 | box - pbp - pit | W2 | 73-73 | 4 | 8 | 17 | 2:50 | 33,028 | Felix Pena | Yovani Gallardo (R) | Felix Pena | Yovani Gallardo | None | |
| 2018-09-13 | Thu | SEA | AL | H | N | 147 | L | 2-8 | 9 | box - pbp - pit | L1 | 73-74 | 4 | 8 | 18 | 3:19 | 33,328 | Odrisamer Despaigne | Mike Leake (R) | Mike Leake | Odrisamer Despaigne | None | |
| 2018-09-14 | Fri | SEA | AL | H | N | 148 | L | 0-5 | 9 | box - pbp - pit | L2 | 73-75 | 4 | 8 | 17 | 3:22 | 39,872 | Matt Shoemaker | Roenis Elias (L) | Adam Warren | Matt Shoemaker | None | |
| 2018-09-15 | Sat | SEA | AL | H | N | 149 | L | 5-6 | 9 | box - pbp - pit | L3 | 73-76 | 4 | 8 | 18 | 3:06 | 42,292 | Andrew Heaney | Erasmo Ramirez (R) | James Pazos | Jose Alvarez | Edwin Diaz | |
| 2018-09-16 | Sun | SEA | AL | H | D | 150 | W | 4-3 | 9 | box - pbp - pit | W1 | 74-76 | 4 | 8 | 18 | 2:55 | 35,578 | Jaime Barria | Marco Gonzales (L) | Taylor Cole | Nick Vincent | Ty Buttrey | |
| 2018-09-18 | Tue | OAK | AL | A | N | 151 | W | 9-7 | 9 | box - pbp - pit | W2 | 75-76 | 4 | 8 | 18 | 3:42 | 15,031 | Tyler Skaggs | Liam Hendriks (R) | Noe Ramirez | Lou Trivino | Ty Buttrey | |
| 2018-09-19 | Wed | OAK | AL | A | N | 152 | L | 0-10 | 9 | box - pbp - pit | L1 | 75-77 | 4 | 8 | 18 | 2:23 | 16,425 | Felix Pena | Brett Anderson (L) | Brett Anderson | Felix Pena | None | |
| 2018-09-20 | Thu | OAK | AL | A | D | 153 | L | 3-21 | 9 | box - pbp - pit | L2 | 75-78 | 4 | 8 | 18 | 3:22 | 17,217 | Matt Shoemaker | Edwin Jackson (R) | Edwin Jackson | Matt Shoemaker | None | |
| 2018-09-21 | Fri | HOU | AL | A | N | 154 | L | 3-11 | 9 | box - pbp - pit | L3 | 75-79 | 4 | 8 | 18 | 2:56 | 39,977 | Andrew Heaney | Gerrit Cole (R) | Gerrit Cole | Andrew Heaney | None | |
| 2018-09-22 | Sat | HOU | AL | A | N | 155 | L | 5-10 | 9 | box - pbp - pit | L4 | 75-80 | 4 | 8 | 18 | 4:04 | 41,822 | Jaime Barria | Justin Verlander (R) | Collin McHugh | Ty Buttrey | None | |
| 2018-09-23 | Sun | HOU | AL | A | D | 156 | L | 2-6 | 9 | box - pbp - pit | L5 | 75-81 | 4 | 8 | 18 | 3:11 | 43,247 | Tyler Skaggs | Charlie Morton (R) | Framber Valdez | Tyler Skaggs | None | |
| 2018-09-24 | Mon | TEX | AL | H | N | 157 | W | 5-4 | 11 | box - pbp - pit | W1 | 76-81 | 4 | 8 | 18 | 3:12 | 29,052 | Felix Pena | Adrian Sampson (R) | Taylor Cole | Matt Moore | None | |
| 2018-09-25 | Tue | TEX | AL | H | N | 158 | W | 4-1 | 9 | box - pbp - pit | W2 | 77-81 | 4 | 8 | 18 | 3:01 | 36,308 | Matt Shoemaker | Yovani Gallardo (R) | Noe Ramirez | Yovani Gallardo | Hansel Robles | |
| 2018-09-26 | Wed | TEX | AL | H | N | 159 | W | 3-2 | 9 | box - pbp - pit | W3 | 78-81 | 4 | 8 | 18 | 2:41 | 35,991 | Andrew Heaney | Yohander Mendez (L) | Jose Alvarez | Chris Martin | Jim Johnson | |
| 2018-09-28 | Fri | OAK | AL | H | N | 160 | W | 8-5 | 9 | box - pbp - pit | W4 | 79-81 | 4 | 8 | 17 | 3:17 | 35,041 | Jaime Barria | Lou Trivino (R) | Taylor Cole | Michael Fiers | Hansel Robles | |
| 2018-09-29 | Sat | OAK | AL | H | N | 161 | L | 2-5 | 9 | box - pbp - pit | L1 | 79-82 | 4 | 8 | 17 | 3:11 | 43,762 | Tyler Skaggs | Liam Hendriks (R) | Trevor Cahill | Tyler Skaggs | Blake Treinen | |
| 2018-09-30 | Sun | OAK | AL | H | D | 162 | W | 5-4 | 9 | box - pbp - pit | W1 | 80-82 | 4 | 8 | 17 | 2:40 | 36,892 | Matt Shoemaker | Brett Anderson (L) | Parker Bridwell | Chris Hatcher | None |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 162 | 80 | 82 | .494 | 721 | 722 | -1 |
| Home Games | 81 | 42 | 39 | .519 | 355 | 355 | 0 |
| Away Games | 81 | 38 | 43 | .469 | 366 | 367 | -1 |
| Night Games | 119 | 61 | 58 | .513 | 531 | 525 | +6 |
| Day Games | 43 | 19 | 24 | .442 | 190 | 197 | -7 |
| March/April | 28 | 16 | 12 | .571 | 130 | 126 | +4 |
| May | 29 | 14 | 15 | .483 | 133 | 114 | +19 |
| June | 27 | 13 | 14 | .481 | 113 | 113 | 0 |
| July | 24 | 11 | 13 | .458 | 118 | 109 | +9 |
| August | 27 | 12 | 15 | .444 | 119 | 122 | -3 |
| Sept/Oct | 27 | 14 | 13 | .519 | 108 | 138 | -30 |
| 1-Run Games | 41 | 26 | 15 | .634 | 148 | 137 | +11 |
| Close Games (1-2-3 Runs) | 100 | 47 | 53 | .470 | 368 | 388 | -20 |
| Blowouts (7+ runs) | 22 | 12 | 10 | .545 | 138 | 130 | +8 |
| Extra Innings | 12 | 5 | 7 | .417 | 55 | 56 | -1 |
| Shutouts | 19 | 9 | 10 | .474 | 33 | 54 | -21 |
| vs LHSP | 51 | 22 | 29 | .431 | 192 | 221 | -29 |
| vs RHSP | 111 | 58 | 53 | .523 | 529 | 501 | +28 |
| vs Division | 76 | 37 | 39 | .487 | 351 | 356 | -5 |
| vs League | 142 | 70 | 72 | .493 | 644 | 644 | 0 |
| InterLeague | 20 | 10 | 10 | .500 | 77 | 78 | -1 |
