| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-04-06 | Mon | DET | AL | A | D | 1 | L | 0-4 | 9 | box - pbp - pit | L1 | 0-1 | 5 | 11 | 24 | 2:30 | 45,030 | Phil Hughes | David Price (L) | David Price | Phil Hughes | Joe Nathan | |
| 2015-04-08 | Wed | DET | AL | A | D | 2 | L | 0-11 | 9 | box - pbp - pit | L2 | 0-2 | 5 | 14 | 27 | 3:06 | 28,280 | Ricky Nolasco | Anibal Sanchez (R) | Anibal Sanchez | Ricky Nolasco | None | |
| 2015-04-09 | Thu | DET | AL | A | D | 3 | L | 1-7 | 9 | box - pbp - pit | L3 | 0-3 | 5 | 14 | 30 | 2:43 | 26,782 | Kyle Gibson | Shane Greene (R) | Shane Greene | Kyle Gibson | None | |
| 2015-04-10 | Fri | CHA | AL | A | D | 4 | W | 6-0 | 9 | box - pbp - pit | W1 | 1-3 | 4 | 14 | 26 | 3:01 | 38,533 | Tom Milone | Hector Noesi (R) | Tom Milone | Hector Noesi | Brian Duensing | |
| 2015-04-11 | Sat | CHA | AL | A | D | 5 | L | 4-5 | 9 | box - pbp - pit | L1 | 1-4 | 5 | 13 | 26 | 2:54 | 22,317 | Mike Pelfrey | Jeff Samardzija (R) | Zach Duke | Blaine Boyer | David Robertson | |
| 2015-04-12 | Sun | CHA | AL | A | D | 6 | L | 2-6 | 9 | box - pbp - pit | L2 | 1-5 | 5 | 15 | 28 | 2:56 | 23,057 | Phil Hughes | Chris Sale (L) | Chris Sale | Phil Hughes | None | |
| 2015-04-13 | Mon | KCA | AL | H | D | 7 | L | 3-12 | 9 | box - pbp - pit | L3 | 1-6 | 5 | 15 | 30 | 2:50 | 40,123 | Trevor May | Danny Duffy (L) | Danny Duffy | Trevor May | None | |
| 2015-04-15 | Wed | KCA | AL | H | N | 8 | W | 3-1 | 9 | box - pbp - pit | W1 | 2-6 | 5 | 15 | 29 | 2:25 | 21,362 | Kyle Gibson | Edinson Volquez (R) | Kyle Gibson | Edinson Volquez | Glen Perkins | |
| 2015-04-16 | Thu | KCA | AL | H | D | 9 | W | 8-5 | 9 | box - pbp - pit | W2 | 3-6 | 5 | 14 | 24 | 3:01 | 17,449 | Tom Milone | Jason Vargas (L) | Tom Milone | Jason Vargas | Glen Perkins | |
| 2015-04-17 | Fri | CLE | AL | H | N | 10 | W | 3-2 | 11 | box - pbp - pit | W3 | 4-6 | 3 | 11 | 21 | 3:38 | 21,307 | Mike Pelfrey | Corey Kluber (R) | Blaine Boyer | Bryan Shaw | None | |
| 2015-04-18 | Sat | CLE | AL | H | D | 11 | L | 2-4 | 9 | box - pbp - pit | L1 | 4-7 | 5 | 14 | 25 | 2:33 | 23,949 | Phil Hughes | Danny Salazar (R) | Danny Salazar | Phil Hughes | Cody Allen | |
| 2015-04-19 | Sun | CLE | AL | H | D | 12 | W | 7-2 | 9 | box - pbp - pit | W1 | 5-7 | 3 | 10 | 21 | 2:45 | 17,923 | Trevor May | TJ House (L) | Trevor May | TJ House | None | |
| 2015-04-20 | Mon | KCA | AL | A | N | 13 | L | 1-7 | 9 | box - pbp - pit | L1 | 5-8 | 4 | 11 | 25 | 2:43 | 20,393 | Kyle Gibson | Edinson Volquez (R) | Edinson Volquez | Kyle Gibson | None | |
| 2015-04-21 | Tue | KCA | AL | A | N | 14 | L | 5-6 | 9 | box - pbp - pit | L2 | 5-9 | 5 | 14 | 26 | 2:55 | 20,990 | Tom Milone | Jason Vargas (L) | Chris Young | Casey Fien | Wade Davis | |
| 2015-04-22 | Wed | KCA | AL | A | N | 15 | W | 3-0 | 9 | box - pbp - pit | W1 | 6-9 | 4 | 11 | 24 | 2:47 | 24,721 | Mike Pelfrey | Jeremy Guthrie (R) | Mike Pelfrey | Jeremy Guthrie | Glen Perkins | |
| 2015-04-24 | Fri | SEA | AL | A | N | 16 | L | 0-2 | 9 | box - pbp - pit | L1 | 6-10 | 5 | 14 | 26 | 2:03 | 25,215 | Phil Hughes | Felix Hernandez (R) | Felix Hernandez | Phil Hughes | None | |
| 2015-04-25 | Sat | SEA | AL | A | N | 17 | W | 8-5 | 9 | box - pbp - pit | W1 | 7-10 | 4 | 13 | 24 | 3:26 | 33,566 | Trevor May | James Paxton (L) | Tim Stauffer | James Paxton | Glen Perkins | |
| 2015-04-26 | Sun | SEA | AL | A | D | 18 | W | 4-2 | 11 | box - pbp - pit | W2 | 8-10 | 4 | 11 | 20 | 3:40 | 35,242 | Kyle Gibson | Roenis Elias (L) | Casey Fien | Tyler Olson | Glen Perkins | |
| 2015-04-27 | Mon | DET | AL | H | N | 19 | L | 4-5 | 9 | box - pbp - pit | L1 | 8-11 | 4 | 12 | 22 | 3:17 | 18,054 | Tom Milone | David Price (L) | David Price | Tom Milone | Joakim Soria | |
| 2015-04-28 | Tue | DET | AL | H | N | 20 | W | 3-2 | 9 | box - pbp - pit | W1 | 9-11 | 4 | 11 | 21 | 2:40 | 18,169 | Mike Pelfrey | Anibal Sanchez (R) | Mike Pelfrey | Anibal Sanchez | Glen Perkins | |
| 2015-04-29 | Wed | DET | AL | H | D | 21 | L | 7-10 | 9 | box - pbp - pit | L1 | 9-12 | 4 | 12 | 23 | 3:33 | 19,447 | Phil Hughes | Shane Greene (R) | Tom Gorzelanny | Casey Fien | Joakim Soria | |
| 2015-04-30 | Thu | CHA | AL | H | N | 22 | W | 12-2 | 9 | box - pbp - pit | W1 | 10-12 | 3 | 11 | 22 | 2:40 | 20,736 | Trevor May | Chris Sale (L) | Trevor May | Chris Sale | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-05-01 | Fri | CHA | AL | H | N | 23 | W | 1-0 | 9 | box - pbp - pit | W2 | 11-12 | 3 | 7 | 16 | 2:32 | 22,794 | Kyle Gibson | Jose Quintana (L) | Kyle Gibson | Jose Quintana | Glen Perkins | |
| 2015-05-02 | Sat | CHA | AL | H | D | 24 | W | 5-3 | 9 | box - pbp - pit | W3 | 12-12 | 3 | 8 | 11 | 3:05 | 30,551 | Ricky Nolasco | Hector Noesi (R) | Ricky Nolasco | Hector Noesi | Glen Perkins | |
| 2015-05-03 | Sun | CHA | AL | H | D | 25 | W | 13-3 | 9 | box - pbp - pit | W4 | 13-12 | 3 | 7 | 11 | 3:20 | 22,423 | Mike Pelfrey | John Danks (L) | Ryan Pressly | John Danks | None | |
| 2015-05-04 | Mon | OAK | AL | H | N | 26 | W | 8-7 | 9 | box - pbp - pit | W5 | 14-12 | 3 | 6 | 9 | 3:10 | 20,605 | Phil Hughes | Jesse Hahn (R) | Phil Hughes | Jesse Hahn | Glen Perkins | |
| 2015-05-05 | Tue | OAK | AL | H | N | 27 | L | 1-2 | 9 | box - pbp - pit | L1 | 14-13 | 3 | 6 | 10 | 2:43 | 18,135 | Trevor May | Jesse Chavez (R) | Jesse Chavez | Trevor May | Tyler Clippard | |
| 2015-05-06 | Wed | OAK | AL | H | N | 28 | W | 13-0 | 9 | box - pbp - pit | W1 | 15-13 | 3 | 6 | 10 | 2:56 | 18,866 | Kyle Gibson | Scott Kazmir (L) | Kyle Gibson | Scott Kazmir | None | |
| 2015-05-07 | Thu | OAK | AL | H | D | 29 | W | 6-5 | 9 | box - pbp - pit | W2 | 16-13 | 3 | 5 | 8 | 2:57 | 22,379 | Ricky Nolasco | Drew Pomeranz (L) | Ricky Nolasco | Drew Pomeranz | Glen Perkins | |
| 2015-05-08 | Fri | CLE | AL | A | N | 30 | W | 9-3 | 9 | box - pbp - pit | W3 | 17-13 | 3 | 5 | 8 | 2:47 | 19,102 | Mike Pelfrey | Trevor Bauer (R) | Mike Pelfrey | Trevor Bauer | None | |
| 2015-05-09 | Sat | CLE | AL | A | D | 31 | W | 7-4 | 9 | box - pbp - pit | W4 | 18-13 | 3 | 5 | 8 | 3:02 | 16,199 | Phil Hughes | Bruce Chen (L) | Phil Hughes | Bruce Chen | Glen Perkins | |
| 2015-05-10 | Sun | CLE | AL | A | D | 32 | L | 2-8 | 9 | box - pbp - pit | L1 | 18-14 | 3 | 5 | 8 | 2:37 | 13,769 | Trevor May | Danny Salazar (R) | Danny Salazar | Trevor May | None | |
| 2015-05-12 | Tue | DET | AL | A | N | 33 | L | 1-2 | 10 | box - pbp - pit | L2 | 18-15 | 3 | 5 | 8 | 2:56 | 26,177 | Kyle Gibson | Alfredo Simon (R) | Angel Nesbitt | Ryan Pressly | None | |
| 2015-05-13 | Wed | DET | AL | A | N | 34 | W | 6-2 | 9 | box - pbp - pit | W1 | 19-15 | 3 | 5 | 8 | 3:07 | 27,163 | Ricky Nolasco | Kyle Lobstein (L) | Ricky Nolasco | Kyle Lobstein | None | |
| 2015-05-14 | Thu | DET | AL | A | D | 35 | L | 1-13 | 9 | box - pbp - pit | L1 | 19-16 | 3 | 6 | 10 | 3:03 | 31,785 | Mike Pelfrey | Anibal Sanchez (R) | Anibal Sanchez | Mike Pelfrey | None | |
| 2015-05-15 | Fri | TBA | AL | H | N | 36 | W | 3-2 | 9 | box - pbp - pit | W1 | 20-16 | 3 | 5 | 8 | 2:29 | 24,018 | Phil Hughes | Jake Odorizzi (R) | Phil Hughes | Jake Odorizzi | Glen Perkins | |
| 2015-05-16 | Sat | TBA | AL | H | D | 37 | W | 6-4 | 9 | box - pbp - pit | W2 | 21-16 | 3 | 5 | 9 | 3:03 | 27,128 | Trevor May | Alex Colome (R) | Brian Duensing | Kevin Jepsen | Glen Perkins | |
| 2015-05-17 | Sun | TBA | AL | H | D | 38 | L | 3-11 | 9 | box - pbp - pit | L1 | 21-17 | 3 | 5 | 10 | 3:17 | 23,708 | Kyle Gibson | Chris Archer (R) | Chris Archer | Kyle Gibson | None | |
| 2015-05-19 | Tue | PIT | NL | A | N | 39 | W | 8-5 | 9 | box - pbp - pit | W1 | 22-17 | 3 | 4 | 8 | 2:53 | 22,357 | Ricky Nolasco | Francisco Liriano (L) | Ricky Nolasco | Francisco Liriano | Glen Perkins | |
| 2015-05-20 | Wed | PIT | NL | A | N | 40 | W | 4-3 | 13 | box - pbp - pit | W2 | 23-17 | 3 | 4 | 7 | 3:56 | 21,718 | Mike Pelfrey | Jeff Locke (L) | Brian Duensing | Antonio Bastardo | Glen Perkins | |
| 2015-05-22 | Fri | CHA | AL | A | N | 41 | L | 2-3 | 9 | box - pbp - pit | L1 | 23-18 | 3 | 4 | 8 | 2:21 | 21,067 | Phil Hughes | Jeff Samardzija (R) | Jeff Samardzija | Aaron Thompson | David Robertson | |
| 2015-05-23 | Sat | CHA | AL | A | D | 42 | W | 4-3 | 9 | box - pbp - pit | W1 | 24-18 | 3 | 4 | 7 | 2:12 | 38,714 | Trevor May | Chris Sale (L) | Trevor May | Chris Sale | Glen Perkins | |
| 2015-05-24 | Sun | CHA | AL | A | D | 43 | W | 8-1 | 9 | box - pbp - pit | W2 | 25-18 | 2 | 3 | 6 | 2:37 | 30,180 | Kyle Gibson | Jose Quintana (L) | Kyle Gibson | Jose Quintana | None | |
| 2015-05-25 | Mon | BOS | AL | H | D | 44 | W | 7-2 | 9 | box - pbp - pit | W3 | 26-18 | 2 | 3 | 6 | 2:52 | 29,472 | Ricky Nolasco | Joe Kelly (R) | Ricky Nolasco | Joe Kelly | None | |
| 2015-05-26 | Tue | BOS | AL | H | N | 45 | W | 2-1 | 9 | box - pbp - pit | W4 | 27-18 | 2 | 3 | 5 | 2:36 | 23,268 | Mike Pelfrey | Clay Buchholz (R) | Mike Pelfrey | Clay Buchholz | Glen Perkins | |
| 2015-05-27 | Wed | BOS | AL | H | D | 46 | W | 6-4 | 9 | box - pbp - pit | W5 | 28-18 | 2 | 3 | 3 | 2:29 | 30,027 | Phil Hughes | Rick Porcello (R) | Phil Hughes | Rick Porcello | Glen Perkins | |
| 2015-05-29 | Fri | TOR | AL | H | N | 47 | L | 4-6 | 9 | box - pbp - pit | L1 | 28-19 | 2 | 3 | 6 | 2:15 | 24,509 | Trevor May | Mark Buehrle (L) | Mark Buehrle | Glen Perkins | None | |
| 2015-05-30 | Sat | TOR | AL | H | D | 48 | W | 3-2 | 9 | box - pbp - pit | W1 | 29-19 | 2 | 3 | 4 | 2:41 | 32,076 | Kyle Gibson | Aaron Sanchez (R) | Ryan Pressly | Aaron Loup | Blaine Boyer | |
| 2015-05-31 | Sun | TOR | AL | H | D | 49 | W | 6-5 | 9 | box - pbp - pit | W2 | 30-19 | 1 | 1 | 2 | 3:08 | 33,829 | Ricky Nolasco | Drew Hutchison (R) | Ryan Pressly | Roberto Osuna | Glen Perkins | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-06-02 | Tue | BOS | AL | A | N | 50 | L | 0-1 | 9 | box - pbp - pit | L1 | 30-20 | 1 | 2 | 3 | 2:21 | 32,622 | Mike Pelfrey | Clay Buchholz (R) | Clay Buchholz | Mike Pelfrey | Koji Uehara | |
| 2015-06-03 | Wed | BOS | AL | A | D | 51 | L | 3-6 | 9 | box - pbp - pit | L2 | 31-21 | 2 | 3 | 4 | 2:33 | 31,704 | Phil Hughes | Eduardo Rodriguez (L) | Eduardo Rodriguez | Phil Hughes | None | |
| 2015-06-03 | Wed | BOS | AL | A | N | 52 | W | 2-0 | 9 | box - pbp - pit | W1 | 31-21 | 2 | 3 | 4 | 2:15 | 33,291 | Trevor May | Rick Porcello (R) | Trevor May | Rick Porcello | Glen Perkins | |
| 2015-06-04 | Thu | BOS | AL | A | D | 53 | W | 8-4 | 9 | box - pbp - pit | W2 | 32-21 | 1 | 2 | 3 | 3:12 | 33,615 | Tom Milone | Steven Wright (R) | Aaron Thompson | Koji Uehara | None | |
| 2015-06-05 | Fri | MIL | NL | H | N | 54 | L | 5-10 | 9 | box - pbp - pit | L1 | 32-22 | 1 | 2 | 3 | 2:48 | 29,398 | Kyle Gibson | Kyle Lohse (R) | Jeremy Jeffress | Blaine Boyer | None | |
| 2015-06-06 | Sat | MIL | NL | H | D | 55 | L | 2-4 | 9 | box - pbp - pit | L2 | 32-23 | 1 | 2 | 3 | 3:22 | 38,707 | J.R. Graham | Matt Garza (R) | Matt Garza | Ryan Pressly | Francisco Rodriguez | |
| 2015-06-07 | Sun | MIL | NL | H | D | 56 | W | 2-0 | 9 | box - pbp - pit | W1 | 33-23 | 1 | 1 | 2 | 2:53 | 31,911 | Mike Pelfrey | Mike Fiers (R) | Mike Pelfrey | Michael Fiers | Glen Perkins | |
| 2015-06-08 | Mon | KCA | AL | H | N | 57 | L | 1-3 | 9 | box - pbp - pit | L1 | 33-24 | 2 | 2 | 3 | 2:36 | 22,796 | Phil Hughes | Jason Vargas (L) | Jason Vargas | Phil Hughes | Greg Holland | |
| 2015-06-09 | Tue | KCA | AL | H | N | 58 | L | 0-2 | 9 | box - pbp - pit | L2 | 33-25 | 2 | 3 | 4 | 2:50 | 22,497 | Trevor May | Chris Young (R) | Chris Young | Trevor May | Greg Holland | |
| 2015-06-10 | Wed | KCA | AL | H | N | 59 | L | 2-7 | 9 | box - pbp - pit | L3 | 33-26 | 2 | 3 | 5 | 2:56 | 28,434 | Kyle Gibson | Edinson Volquez (R) | Edinson Volquez | Kyle Gibson | None | |
| 2015-06-12 | Fri | TEX | AL | A | N | 60 | L | 2-6 | 9 | box - pbp - pit | L4 | 33-27 | 2 | 4 | 5 | 2:39 | 41,765 | Tom Milone | Wandy Rodriguez (L) | Tanner Scheppers | Aaron Thompson | None | |
| 2015-06-13 | Sat | TEX | AL | A | D | 61 | L | 7-11 | 9 | box - pbp - pit | L5 | 33-28 | 2 | 4 | 8 | 2:44 | 28,661 | Mike Pelfrey | Colby Lewis (R) | Colby Lewis | Mike Pelfrey | None | |
| 2015-06-14 | Sun | TEX | AL | A | D | 62 | W | 4-3 | 9 | box - pbp - pit | W1 | 34-28 | 2 | 4 | 8 | 2:49 | 33,970 | Phil Hughes | Nick Martinez (R) | Casey Fien | Shawn Tolleson | Glen Perkins | |
| 2015-06-15 | Mon | SLN | NL | A | N | 63 | L | 2-3 | 9 | box - pbp - pit | L1 | 34-29 | 2 | 4 | 9 | 2:32 | 43,174 | Trevor May | John Lackey (R) | John Lackey | Trevor May | Kevin Siegrist | |
| 2015-06-16 | Tue | SLN | NL | A | D | 64 | L | 2-3 | 9 | box - pbp - pit | L2 | 34-30 | 2 | 6 | 11 | 2:31 | 41,203 | Kyle Gibson | Michael Wacha (R) | Michael Wacha | Kyle Gibson | Kevin Siegrist | |
| 2015-06-17 | Wed | SLN | NL | H | N | 65 | W | 3-1 | 9 | box - pbp - pit | W1 | 35-30 | 2 | 6 | 10 | 2:47 | 34,381 | Tom Milone | Carlos Martinez (R) | Tom Milone | Carlos Martinez | Glen Perkins | |
| 2015-06-18 | Thu | SLN | NL | H | D | 66 | W | 2-1 | 9 | box - pbp - pit | W2 | 36-30 | 2 | 4 | 9 | 2:38 | 34,648 | Mike Pelfrey | Jaime Garcia (L) | Blaine Boyer | Carlos Villanueva | None | |
| 2015-06-19 | Fri | CHN | NL | H | N | 67 | W | 7-2 | 9 | box - pbp - pit | W3 | 37-30 | 2 | 5 | 7 | 2:18 | 36,817 | Phil Hughes | Kyle Hendricks (R) | Phil Hughes | Kyle Hendricks | None | |
| 2015-06-20 | Sat | CHN | NL | H | D | 68 | L | 1-4 | 10 | box - pbp - pit | L1 | 37-31 | 2 | 5 | 9 | 3:17 | 40,066 | Trevor May | Jon Lester (L) | Jason Motte | Blaine Boyer | Hector Rondon | |
| 2015-06-21 | Sun | CHN | NL | H | D | 69 | L | 0-8 | 9 | box - pbp - pit | L2 | 37-32 | 2 | 5 | 9 | 2:59 | 40,273 | Kyle Gibson | Jake Arrieta (R) | Jake Arrieta | Kyle Gibson | None | |
| 2015-06-22 | Mon | CHA | AL | H | N | 70 | W | 13-2 | 9 | box - pbp - pit | W1 | 38-32 | 2 | 5 | 8 | 2:55 | 24,094 | Tom Milone | John Danks (L) | Tom Milone | John Danks | None | |
| 2015-06-23 | Tue | CHA | AL | H | N | 71 | L | 2-6 | 9 | box - pbp - pit | L1 | 38-33 | 2 | 5 | 10 | 2:57 | 27,349 | Mike Pelfrey | Jeff Samardzija (R) | Jeff Samardzija | Mike Pelfrey | Jake Petricka | |
| 2015-06-24 | Wed | CHA | AL | H | D | 72 | W | 6-1 | 9 | box - pbp - pit | W1 | 39-33 | 2 | 5 | 10 | 2:19 | 28,854 | Phil Hughes | Chris Sale (L) | Phil Hughes | Chris Sale | None | |
| 2015-06-26 | Fri | MIL | NL | A | N | 73 | L | 4-10 | 9 | box - pbp - pit | L1 | 39-34 | 2 | 6 | 11 | 2:49 | 33,296 | Trevor May | Kyle Lohse (R) | Kyle Lohse | Trevor May | None | |
| 2015-06-27 | Sat | MIL | NL | A | D | 74 | W | 5-2 | 9 | box - pbp - pit | W1 | 40-34 | 2 | 5 | 9 | 2:47 | 39,977 | Kyle Gibson | Matt Garza (R) | Kyle Gibson | Matt Garza | Glen Perkins | |
| 2015-06-28 | Sun | MIL | NL | A | D | 75 | L | 3-5 | 9 | box - pbp - pit | L1 | 40-35 | 2 | 6 | 11 | 3:02 | 38,958 | Tom Milone | Mike Fiers (R) | Will Smith | Casey Fien | None | |
| 2015-06-29 | Mon | CIN | NL | A | N | 76 | L | 7-11 | 9 | box - pbp - pit | L2 | 40-36 | 2 | 6 | 12 | 3:34 | 28,904 | Mike Pelfrey | Mike Leake (R) | Nathan Adcock | Mike Pelfrey | None | |
| 2015-06-30 | Tue | CIN | NL | A | N | 77 | W | 8-5 | 9 | box - pbp - pit | W1 | 41-36 | 2 | 4 | 10 | 3:19 | 28,556 | Phil Hughes | Anthony DeSclafani (R) | Phil Hughes | Anthony DeSclafani | Glen Perkins | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-07-01 | Wed | CIN | NL | A | D | 78 | L | 1-2 | 9 | box - pbp - pit | L1 | 41-37 | 2 | 5 | 11 | 2:40 | 26,459 | Trevor May | Johnny Cueto (R) | Johnny Cueto | Trevor May | Aroldis Chapman | |
| 2015-07-02 | Thu | KCA | AL | A | N | 79 | W | 2-0 | 9 | box - pbp - pit | W1 | 42-37 | 2 | 5 | 9 | 2:54 | 37,196 | Kyle Gibson | Chris Young (R) | Kyle Gibson | Chris Young | Glen Perkins | |
| 2015-07-03 | Fri | KCA | AL | A | N | 80 | L | 2-3 | 10 | box - pbp - pit | L1 | 42-38 | 2 | 4 | 9 | 3:14 | 38,868 | Tom Milone | Jeremy Guthrie (R) | Wade Davis | Aaron Thompson | None | |
| 2015-07-04 | Sat | KCA | AL | A | N | 81 | W | 5-3 | 9 | box - pbp - pit | W1 | 43-38 | 2 | 4 | 9 | 3:25 | 37,917 | Mike Pelfrey | Joe Blanton (R) | Brian Duensing | Joe Blanton | Glen Perkins | |
| 2015-07-05 | Sun | KCA | AL | A | D | 82 | L | 2-3 | 9 | box - pbp - pit | L1 | 43-39 | 2 | 6 | 11 | 2:20 | 29,427 | Ervin Santana | Danny Duffy (L) | Greg Holland | Blaine Boyer | None | |
| 2015-07-06 | Mon | BAL | AL | H | N | 83 | W | 4-2 | 10 | box - pbp - pit | W1 | 44-39 | 2 | 5 | 10 | 2:49 | 23,213 | Phil Hughes | Wei-Yin Chen (L) | Trevor May | Tommy Hunter | None | |
| 2015-07-07 | Tue | BAL | AL | H | N | 84 | W | 8-3 | 9 | box - pbp - pit | W2 | 45-39 | 2 | 4 | 9 | 2:48 | 25,091 | Kyle Gibson | Kevin Gausman (R) | Kyle Gibson | Kevin Gausman | None | |
| 2015-07-08 | Wed | BAL | AL | H | D | 85 | W | 5-3 | 9 | box - pbp - pit | W3 | 46-39 | 2 | 4 | 9 | 2:59 | 29,289 | Tom Milone | Ubaldo Jimenez (R) | Tom Milone | Bud Norris | Glen Perkins | |
| 2015-07-09 | Thu | DET | AL | H | N | 86 | L | 2-4 | 9 | box - pbp - pit | L1 | 46-40 | 2 | 5 | 10 | 3:01 | 29,724 | Mike Pelfrey | David Price (L) | David Price | Mike Pelfrey | Joakim Soria | |
| 2015-07-10 | Fri | DET | AL | H | N | 87 | W | 8-6 | 9 | box - pbp - pit | W1 | 47-40 | 2 | 5 | 10 | 3:22 | 31,545 | Ervin Santana | Justin Verlander (R) | Trevor May | Joakim Soria | None | |
| 2015-07-11 | Sat | DET | AL | H | D | 88 | W | 9-5 | 9 | box - pbp - pit | W2 | 48-40 | 2 | 2 | 6 | 3:27 | 32,365 | Phil Hughes | Alfredo Simon (R) | Phil Hughes | Alfredo Simon | None | |
| 2015-07-12 | Sun | DET | AL | H | D | 89 | W | 7-1 | 9 | box - pbp - pit | W3 | 49-40 | 2 | 2 | 6 | 2:44 | 27,936 | Kyle Gibson | Shane Greene (R) | Kyle Gibson | Shane Greene | None | |
| 2015-07-17 | Fri | OAK | AL | A | N | 90 | W | 5-0 | 9 | box - pbp - pit | W4 | 50-40 | 2 | 2 | 6 | 2:42 | 23,462 | Ervin Santana | Sonny Gray (R) | Ervin Santana | Sonny Gray | None | |
| 2015-07-18 | Sat | OAK | AL | A | N | 91 | L | 2-3 | 10 | box - pbp - pit | L1 | 50-41 | 2 | 3 | 7 | 3:00 | 30,778 | Phil Hughes | Scott Kazmir (L) | Drew Pomeranz | Casey Fien | None | |
| 2015-07-19 | Sun | OAK | AL | A | D | 92 | L | 1-14 | 9 | box - pbp - pit | L2 | 50-42 | 2 | 4 | 9 | 2:49 | 20,286 | Tom Milone | Jesse Chavez (R) | Jesse Chavez | Tom Milone | None | |
| 2015-07-21 | Tue | ANA | AL | A | N | 93 | L | 0-7 | 9 | box - pbp - pit | L3 | 50-43 | 2 | 5 | 10 | 2:52 | 38,937 | Kyle Gibson | Matt Shoemaker (R) | Matt Shoemaker | Kyle Gibson | None | |
| 2015-07-22 | Wed | ANA | AL | A | N | 94 | L | 2-5 | 9 | box - pbp - pit | L4 | 50-44 | 2 | 5 | 11 | 3:03 | 40,239 | Mike Pelfrey | CJ Wilson (L) | C.J. Wilson | Mike Pelfrey | Huston Street | |
| 2015-07-23 | Thu | ANA | AL | A | D | 95 | W | 3-0 | 9 | box - pbp - pit | W1 | 51-44 | 2 | 5 | 10 | 2:16 | 36,134 | Ervin Santana | Garrett Richards (R) | Ervin Santana | Garrett Richards | Glen Perkins | |
| 2015-07-24 | Fri | NYA | AL | H | N | 96 | W | 10-1 | 9 | box - pbp - pit | W2 | 52-44 | 2 | 5 | 9 | 2:57 | 34,334 | Phil Hughes | Michael Pineda (R) | Phil Hughes | Michael Pineda | None | |
| 2015-07-25 | Sat | NYA | AL | H | N | 97 | L | 5-8 | 9 | box - pbp - pit | L1 | 52-45 | 2 | 5 | 10 | 2:54 | 40,660 | Tom Milone | CC Sabathia (L) | Adam Warren | Glen Perkins | Andrew Miller | |
| 2015-07-26 | Sun | NYA | AL | H | D | 98 | L | 2-7 | 9 | box - pbp - pit | L2 | 52-46 | 2 | 5 | 10 | 3:00 | 37,391 | Kyle Gibson | Nathan Eovaldi (R) | Nathan Eovaldi | Kyle Gibson | None | |
| 2015-07-28 | Tue | PIT | NL | H | N | 99 | L | 7-8 | 9 | box - pbp - pit | L3 | 52-47 | 2 | 5 | 10 | 3:24 | 30,795 | Mike Pelfrey | Charlie Morton (R) | Mark Melancon | Glen Perkins | None | |
| 2015-07-29 | Wed | PIT | NL | H | D | 100 | L | 4-10 | 9 | box - pbp - pit | L4 | 52-48 | 2 | 5 | 11 | 3:29 | 37,273 | Ervin Santana | Francisco Liriano (L) | Francisco Liriano | Ervin Santana | None | |
| 2015-07-30 | Thu | SEA | AL | H | N | 101 | W | 9-5 | 9 | box - pbp - pit | W1 | 53-48 | 2 | 5 | 11 | 3:08 | 30,534 | Phil Hughes | J.A. Happ (L) | Phil Hughes | J.A. Happ | None | |
| 2015-07-31 | Fri | SEA | AL | H | N | 102 | L | 1-6 | 9 | box - pbp - pit | L1 | 53-49 | 2 | 5 | 11 | 2:23 | 27,643 | Tom Milone | Taijuan Walker (R) | Taijuan Walker | Tom Milone | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-08-01 | Sat | SEA | AL | H | N | 103 | W | 3-2 | 9 | box - pbp - pit | W1 | 54-49 | 2 | 5 | 11 | 2:45 | 36,901 | Kyle Gibson | Mike Montgomery (L) | Trevor May | Carson Smith | None | |
| 2015-08-02 | Sun | SEA | AL | H | D | 104 | L | 1-4 | 11 | box - pbp - pit | L1 | 54-50 | 2 | 5 | 12 | 3:12 | 30,325 | Mike Pelfrey | Hisashi Iwakuma (R) | Fernando Rodney | Kevin Jepsen | Tom Wilhelmsen | |
| 2015-08-03 | Mon | TOR | AL | A | D | 105 | L | 1-5 | 9 | box - pbp - pit | L2 | 54-51 | 2 | 5 | 12 | 2:37 | 45,766 | Ervin Santana | David Price (L) | David Price | Ervin Santana | None | |
| 2015-08-04 | Tue | TOR | AL | A | N | 106 | L | 1-3 | 9 | box - pbp - pit | L3 | 54-52 | 2 | 7 | 14 | 2:36 | 26,504 | Phil Hughes | Marco Estrada (R) | Marco Estrada | Phil Hughes | Roberto Osuna | |
| 2015-08-05 | Wed | TOR | AL | A | N | 107 | L | 7-9 | 9 | box - pbp - pit | L4 | 54-53 | 2 | 7 | 15 | 3:06 | 27,725 | Tyler Duffey | Drew Hutchison (R) | Drew Hutchison | Tyler Duffey | LaTroy Hawkins | |
| 2015-08-06 | Thu | TOR | AL | A | N | 108 | L | 3-9 | 9 | box - pbp - pit | L5 | 54-54 | 2 | 8 | 15 | 2:39 | 34,847 | Kyle Gibson | Mark Buehrle (L) | Mark Buehrle | Kyle Gibson | None | |
| 2015-08-07 | Fri | CLE | AL | A | N | 109 | W | 10-9 | 9 | box - pbp - pit | W1 | 55-54 | 2 | 7 | 14 | 3:24 | 30,365 | Mike Pelfrey | Cody Anderson (R) | Trevor May | Bryan Shaw | Glen Perkins | |
| 2015-08-08 | Sat | CLE | AL | A | N | 110 | L | 4-17 | 9 | box - pbp - pit | L1 | 55-55 | 2 | 8 | 15 | 3:34 | 31,666 | Ervin Santana | Trevor Bauer (R) | Trevor Bauer | Ervin Santana | None | |
| 2015-08-09 | Sun | CLE | AL | A | D | 111 | L | 1-8 | 9 | box - pbp - pit | L2 | 55-56 | 2 | 9 | 16 | 2:37 | 21,305 | Phil Hughes | Corey Kluber (R) | Corey Kluber | Phil Hughes | None | |
| 2015-08-11 | Tue | TEX | AL | H | N | 112 | W | 3-2 | 9 | box - pbp - pit | W1 | 56-56 | 2 | 8 | 16 | 3:19 | 26,663 | Kyle Gibson | Yovani Gallardo (R) | Glen Perkins | Spencer Patton | None | |
| 2015-08-12 | Wed | TEX | AL | H | N | 113 | W | 11-1 | 9 | box - pbp - pit | W2 | 57-56 | 2 | 7 | 15 | 2:53 | 30,683 | Mike Pelfrey | Nick Martinez (R) | Mike Pelfrey | Nick Martinez | None | |
| 2015-08-13 | Thu | TEX | AL | H | D | 114 | L | 5-6 | 9 | box - pbp - pit | L1 | 57-57 | 2 | 8 | 15 | 2:59 | 30,357 | Ervin Santana | () | Keone Kela | Casey Fien | Shawn Tolleson | |
| 2015-08-14 | Fri | CLE | AL | H | N | 115 | L | 1-6 | 9 | box - pbp - pit | L2 | 57-58 | 2 | 9 | 16 | 2:26 | 26,910 | Trevor May | Corey Kluber (R) | Corey Kluber | Trevor May | None | |
| 2015-08-15 | Sat | CLE | AL | H | N | 116 | W | 4-1 | 9 | box - pbp - pit | W1 | 58-58 | 2 | 8 | 15 | 2:27 | 30,601 | Tyler Duffey | Josh Tomlin (R) | Tyler Duffey | Josh Tomlin | None | |
| 2015-08-16 | Sun | CLE | AL | H | D | 117 | W | 4-1 | 9 | box - pbp - pit | W2 | 59-58 | 2 | 8 | 14 | 2:48 | 27,244 | Tom Milone | Carlos Carrasco (R) | Tom Milone | Carlos Carrasco | Glen Perkins | |
| 2015-08-17 | Mon | NYA | AL | A | N | 118 | L | 7-8 | 10 | box - pbp - pit | L1 | 59-59 | 2 | 8 | 15 | 4:13 | 38,493 | Kyle Gibson | Bryan Mitchell (R) | Andrew Miller | Glen Perkins | None | |
| 2015-08-18 | Tue | NYA | AL | A | N | 119 | L | 4-8 | 9 | box - pbp - pit | L2 | 59-60 | 2 | 8 | 15 | 3:16 | 38,007 | Mike Pelfrey | CC Sabathia (L) | NIck Rumbelow | J.R. Graham | Andrew Miller | |
| 2015-08-19 | Wed | NYA | AL | A | D | 120 | L | 3-4 | 9 | box - pbp - pit | L3 | 59-61 | 2 | 8 | 15 | 2:34 | 38,086 | Ervin Santana | Nathan Eovaldi (R) | Nathan Eovaldi | Ervin Santana | Dellin Betances | |
| 2015-08-20 | Thu | BAL | AL | A | N | 121 | W | 15-2 | 9 | box - pbp - pit | W1 | 60-61 | 2 | 8 | 15 | 2:51 | 20,109 | Tyler Duffey | Miguel Gonzalez (R) | Tyler Duffey | Miguel Gonzalez | None | |
| 2015-08-21 | Fri | BAL | AL | A | N | 122 | W | 4-3 | 9 | box - pbp - pit | W2 | 61-61 | 2 | 8 | 15 | 3:06 | 32,025 | Tom Milone | Wei-Yin Chen (L) | Casey Fien | Darren O'Day | Kevin Jepsen | |
| 2015-08-22 | Sat | BAL | AL | A | N | 123 | W | 3-2 | 9 | box - pbp - pit | W3 | 62-61 | 2 | 8 | 15 | 3:01 | 35,301 | Kyle Gibson | Chris Tillman (R) | Casey Fien | Chris Tillman | Kevin Jepsen | |
| 2015-08-23 | Sun | BAL | AL | A | D | 124 | W | 4-3 | 12 | box - pbp - pit | W4 | 63-61 | 2 | 7 | 12 | 4:24 | 35,144 | Mike Pelfrey | Kevin Gausman (R) | Glen Perkins | Brian Matusz | Tom Milone | |
| 2015-08-25 | Tue | TBA | AL | A | N | 125 | W | 11-7 | 9 | box - pbp - pit | W5 | 64-61 | 2 | 7 | 12 | 3:24 | 9,632 | Ervin Santana | Nate Karns (R) | J.R. Graham | Matt Andriese | None | |
| 2015-08-26 | Wed | TBA | AL | A | N | 126 | W | 5-3 | 9 | box - pbp - pit | W6 | 65-61 | 2 | 5 | 11 | 3:21 | 9,205 | Tyler Duffey | Chris Archer (R) | Brian Duensing | Chris Archer | Kevin Jepsen | |
| 2015-08-27 | Thu | TBA | AL | A | N | 127 | L | 4-5 | 9 | box - pbp - pit | L1 | 65-62 | 2 | 7 | 12 | 2:49 | 9,375 | Tom Milone | Drew Smyly (L) | Brandon Gomes | Tom Milone | Brad Boxberger | |
| 2015-08-28 | Fri | HOU | AL | H | N | 128 | W | 3-0 | 9 | box - pbp - pit | W1 | 66-62 | 2 | 6 | 12 | 2:49 | 28,636 | Kyle Gibson | Scott Kazmir (L) | Kyle Gibson | Scott Kazmir | Kevin Jepsen | |
| 2015-08-29 | Sat | HOU | AL | H | N | 129 | L | 1-4 | 9 | box - pbp - pit | L1 | 66-63 | 2 | 6 | 12 | 3:22 | 38,876 | Mike Pelfrey | Mike Fiers (R) | Michael Fiers | Mike Pelfrey | Luke Gregerson | |
| 2015-08-30 | Sun | HOU | AL | H | D | 130 | W | 7-5 | 9 | box - pbp - pit | W1 | 67-63 | 2 | 6 | 12 | 3:03 | 28,877 | Ervin Santana | Lance McCullers (R) | Ervin Santana | Lance McCullers | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-09-01 | Tue | CHA | AL | H | N | 131 | W | 8-6 | 9 | box - pbp - pit | W2 | 68-63 | 2 | 6 | 12 | 3:06 | 25,803 | Tyler Duffey | Chris Sale (L) | Kevin Jepsen | Zach Duke | Glen Perkins | |
| 2015-09-02 | Wed | CHA | AL | H | N | 132 | W | 3-0 | 9 | box - pbp - pit | W3 | 69-63 | 2 | 6 | 11 | 2:34 | 22,162 | Tom Milone | Carlos Rodon (L) | Tom Milone | Carlos Rodon | Kevin Jepsen | |
| 2015-09-03 | Thu | CHA | AL | H | D | 133 | L | 4-6 | 9 | box - pbp - pit | L1 | 69-64 | 2 | 6 | 11 | 3:26 | 25,339 | Kyle Gibson | Jeff Samardzija (R) | Jeff Samardzija | Casey Fien | David Robertson | |
| 2015-09-04 | Fri | HOU | AL | A | N | 134 | L | 0-8 | 9 | box - pbp - pit | L2 | 69-65 | 2 | 6 | 12 | 2:35 | 27,807 | Mike Pelfrey | Collin McHugh (R) | Collin McHugh | Mike Pelfrey | None | |
| 2015-09-05 | Sat | HOU | AL | A | N | 135 | W | 3-2 | 9 | box - pbp - pit | W1 | 70-65 | 2 | 6 | 11 | 2:45 | 27,643 | Ervin Santana | Lance McCullers (R) | Ervin Santana | Luke Gregerson | Kevin Jepsen | |
| 2015-09-06 | Sun | HOU | AL | A | D | 136 | L | 5-8 | 9 | box - pbp - pit | L1 | 70-66 | 2 | 6 | 13 | 2:55 | 37,648 | Tyler Duffey | Dallas Keuchel (L) | Dallas Keuchel | Trevor May | Luke Gregerson | |
| 2015-09-07 | Mon | KCA | AL | A | N | 137 | W | 6-2 | 9 | box - pbp - pit | W1 | 71-66 | 2 | 6 | 11 | 3:02 | 36,825 | Tom Milone | Yordano Ventura (R) | Tom Milone | Yordano Ventura | None | |
| 2015-09-08 | Tue | KCA | AL | A | N | 138 | L | 2-4 | 9 | box - pbp - pit | L1 | 71-67 | 2 | 6 | 12 | 2:29 | 31,834 | Kyle Gibson | Edinson Volquez (R) | Edinson Volquez | Kyle Gibson | Greg Holland | |
| 2015-09-09 | Wed | KCA | AL | A | N | 139 | W | 3-2 | 12 | box - pbp - pit | W1 | 72-67 | 2 | 6 | 11 | 4:03 | 32,286 | Mike Pelfrey | Kris Medlen (R) | Blaine Boyer | Franklin Morales | Kevin Jepsen | |
| 2015-09-11 | Fri | CHA | AL | A | N | 140 | W | 6-2 | 9 | box - pbp - pit | W2 | 73-67 | 2 | 6 | 11 | 2:58 | 15,641 | Ervin Santana | Erik Johnson (R) | Ervin Santana | Nate Jones | None | |
| 2015-09-12 | Sat | CHA | AL | A | N | 141 | L | 2-8 | 9 | box - pbp - pit | L1 | 73-68 | 2 | 6 | 12 | 3:29 | 26,065 | Tom Milone | Jose Quintana (L) | Jose Quintana | Tom Milone | None | |
| 2015-09-13 | Sun | CHA | AL | A | D | 142 | W | 7-0 | 9 | box - pbp - pit | W1 | 74-68 | 2 | 6 | 12 | 2:57 | 23,159 | Kyle Gibson | Chris Sale (L) | Kyle Gibson | Chris Sale | None | |
| 2015-09-14 | Mon | DET | AL | H | N | 143 | W | 7-1 | 9 | box - pbp - pit | W2 | 75-68 | 2 | 6 | 12 | 2:56 | 17,833 | Tyler Duffey | Kyle Lobstein (L) | Tyler Duffey | Kyle Lobstein | None | |
| 2015-09-15 | Tue | DET | AL | H | N | 144 | L | 4-5 | 9 | box - pbp - pit | L1 | 75-69 | 2 | 6 | 12 | 3:29 | 22,963 | Phil Hughes | Alfredo Simon (R) | Alfredo Simon | Phil Hughes | Bruce Rondon | |
| 2015-09-16 | Wed | DET | AL | H | N | 145 | L | 4-7 | 12 | box - pbp - pit | L2 | 75-70 | 2 | 6 | 12 | 4:17 | 22,509 | Ervin Santana | Daniel Norris (L) | Ian Krol | Brian Duensing | None | |
| 2015-09-17 | Thu | ANA | AL | H | N | 146 | L | 8-11 | 9 | box - pbp - pit | L3 | 75-71 | 2 | 6 | 12 | 3:56 | 18,697 | Tom Milone | Hector Santiago (L) | Mike Morin | A.J. Achter | Huston Street | |
| 2015-09-19 | Sat | ANA | AL | H | D | 147 | L | 3-4 | 12 | box - pbp - pit | L4 | 75-73 | 2 | 7 | 14 | 4:15 | 22,878 | Kyle Gibson | Andrew Heaney (L) | Mike Morin | Blaine Boyer | Huston Street | |
| 2015-09-19 | Sat | ANA | AL | H | N | 148 | L | 2-5 | 9 | box - pbp - pit | L5 | 75-73 | 2 | 7 | 14 | 2:56 | 33,300 | Mike Pelfrey | Garrett Richards (R) | Garrett Richards | Mike Pelfrey | Huston Street | |
| 2015-09-20 | Sun | ANA | AL | H | D | 149 | W | 8-1 | 9 | box - pbp - pit | W1 | 76-73 | 2 | 7 | 13 | 3:02 | 25,302 | Tyler Duffey | Matt Shoemaker (R) | Tyler Duffey | Matt Shoemaker | None | |
| 2015-09-22 | Tue | CLE | AL | H | N | 150 | W | 3-1 | 9 | box - pbp - pit | W2 | 77-73 | 2 | 6 | 13 | 2:47 | 21,850 | Ervin Santana | Danny Salazar (R) | Ervin Santana | Danny Salazar | Kevin Jepsen | |
| 2015-09-23 | Wed | CLE | AL | H | N | 151 | W | 4-2 | 9 | box - pbp - pit | W3 | 78-73 | 2 | 6 | 12 | 2:46 | 17,831 | Phil Hughes | Corey Kluber (R) | Phil Hughes | Corey Kluber | None | |
| 2015-09-24 | Thu | CLE | AL | H | N | 152 | L | 3-6 | 9 | box - pbp - pit | L1 | 78-74 | 2 | 7 | 13 | 3:00 | 21,366 | Kyle Gibson | Cody Anderson (R) | Cody Anderson | Kyle Gibson | Cody Allen | |
| 2015-09-25 | Fri | DET | AL | A | N | 153 | L | 4-6 | 9 | box - pbp - pit | L2 | 78-75 | 2 | 7 | 13 | 3:16 | 31,153 | Mike Pelfrey | Matt Boyd (L) | Alex Wilson | Glen Perkins | Neftali Feliz | |
| 2015-09-26 | Sat | DET | AL | A | N | 154 | W | 6-2 | 9 | box - pbp - pit | W1 | 79-75 | 2 | 7 | 13 | 3:02 | 32,753 | Tyler Duffey | Alfredo Simon (R) | Tyler Duffey | Alfredo Simon | None | |
| 2015-09-27 | Sun | DET | AL | A | D | 155 | W | 7-1 | 9 | box - pbp - pit | W2 | 80-75 | 2 | 7 | 13 | 2:57 | 33,517 | Ervin Santana | Randy Wolf (L) | Ervin Santana | Randy Wolf | None | |
| 2015-09-28 | Mon | CLE | AL | A | N | 156 | W | 4-2 | 9 | box - pbp - pit | W3 | 81-75 | 2 | 7 | 13 | 2:59 | 10,007 | Tom Milone | Corey Kluber (R) | Tom Milone | Corey Kluber | Kevin Jepsen | |
| 2015-09-30 | Wed | CLE | AL | A | D | 157 | W | 7-1 | 9 | box - pbp - pit | W4 | 82-76 | 2 | 7 | 13 | 3:05 | 0 | Kyle Gibson | Carlos Carrasco (R) | Kyle Gibson | Carlos Carrasco | None | |
| 2015-09-30 | Wed | CLE | AL | A | N | 158 | L | 2-10 | 9 | box - pbp - pit | L1 | 82-76 | 2 | 7 | 13 | 2:52 | 10,228 | Mike Pelfrey | Cody Anderson (R) | Cody Anderson | Mike Pelfrey | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2015-10-01 | Thu | CLE | AL | A | N | 159 | W | 4-2 | 9 | box - pbp - pit | W1 | 83-76 | 2 | 7 | 13 | 2:47 | 22,644 | Tyler Duffey | Trevor Bauer (R) | Glen Perkins | Cody Allen | Kevin Jepsen | |
| 2015-10-02 | Fri | KCA | AL | H | N | 160 | L | 1-3 | 9 | box - pbp - pit | L1 | 83-77 | 2 | 7 | 13 | 2:55 | 31,534 | Ervin Santana | Chris Young (R) | Louis Coleman | Ervin Santana | Wade Davis | |
| 2015-10-03 | Sat | KCA | AL | H | D | 161 | L | 1-5 | 9 | box - pbp - pit | L2 | 83-78 | 2 | 7 | 13 | 3:01 | 30,181 | Tom Milone | Yordano Ventura (R) | Yordano Ventura | Blaine Boyer | Wade Davis | |
| 2015-10-04 | Sun | KCA | AL | H | D | 162 | L | 1-6 | 9 | box - pbp - pit | L3 | 83-79 | 2 | 7 | 13 | 3:11 | 24,108 | Ricky Nolasco | Johnny Cueto (R) | Johnny Cueto | Ricky Nolasco | None |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 162 | 83 | 79 | .512 | 696 | 700 | -4 |
| Home Games | 81 | 46 | 35 | .568 | 373 | 323 | +50 |
| Away Games | 81 | 37 | 44 | .457 | 323 | 377 | -54 |
| Night Games | 97 | 51 | 46 | .526 | 427 | 399 | +28 |
| Day Games | 65 | 32 | 33 | .492 | 269 | 301 | -32 |
| March/April | 22 | 10 | 12 | .455 | 86 | 100 | -14 |
| May | 27 | 20 | 7 | .741 | 139 | 104 | +35 |
| June | 28 | 11 | 17 | .393 | 103 | 121 | -18 |
| July | 25 | 12 | 13 | .480 | 106 | 109 | -3 |
| August | 28 | 14 | 14 | .500 | 130 | 137 | -7 |
| Sept/Oct | 32 | 16 | 16 | .500 | 132 | 129 | +3 |
| 1-Run Games | 41 | 21 | 20 | .512 | 143 | 142 | +1 |
| Close Games (1-2-3 Runs) | 99 | 53 | 46 | .535 | 372 | 359 | +13 |
| Blowouts (7+ runs) | 21 | 10 | 11 | .476 | 125 | 132 | -7 |
| Extra Innings | 14 | 6 | 8 | .429 | 43 | 49 | -6 |
| Shutouts | 20 | 12 | 8 | .600 | 50 | 43 | +7 |
| vs LHSP | 54 | 28 | 26 | .519 | 265 | 228 | +37 |
| vs RHSP | 108 | 55 | 53 | .509 | 431 | 472 | -41 |
| vs Division | 76 | 40 | 36 | .526 | 321 | 314 | +7 |
| vs League | 142 | 75 | 67 | .528 | 619 | 603 | +16 |
| InterLeague | 20 | 8 | 12 | .400 | 77 | 97 | -20 |
