| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-04-06 | Fri | ANA | AL | A | N | 1 | L | 0-5 | 9 | box - pbp - pit | L1 | 0-1 | 3 | 11 | 26 | 2:22 | 44,106 | Bruce Chen | Jered Weaver (R) | Jered Weaver | Aaron Crow | None | |
| 2012-04-07 | Sat | ANA | AL | A | D | 2 | W | 6-3 | 9 | box - pbp - pit | W1 | 1-1 | 3 | 8 | 18 | 2:46 | 40,022 | Luke Hochevar | Dan Haren (R) | Luke Hochevar | Dan Haren | None | |
| 2012-04-08 | Sun | ANA | AL | A | D | 3 | W | 7-3 | 9 | box - pbp - pit | W2 | 2-1 | 2 | 7 | 13 | 3:15 | 32,227 | Jonathan Sanchez | Ervin Santana (R) | Jonathan Sanchez | Ervin Santana | Jonathan Broxton | |
| 2012-04-09 | Mon | OAK | AL | A | N | 4 | L | 0-1 | 9 | box - pbp - pit | L1 | 2-2 | 3 | 8 | 18 | 2:34 | 10,054 | Luis Mendoza | Tommy Milone (L) | Tom Milone | Luis Mendoza | Grant Balfour | |
| 2012-04-10 | Tue | OAK | AL | A | N | 5 | W | 3-0 | 8 | box - pbp - pit | W1 | 3-2 | 2 | 7 | 13 | 2:13 | 10,670 | Danny Duffy | Graham Godfrey (R) | Danny Duffy | Graham Godfrey | Aaron Crow | |
| 2012-04-11 | Wed | OAK | AL | A | D | 6 | L | 4-5 | 12 | box - pbp - pit | L1 | 3-3 | 2 | 7 | 15 | 4:10 | 12,390 | Bruce Chen | Brandon McCarthy (R) | Andrew Carignan | Jonathan Broxton | None | |
| 2012-04-13 | Fri | CLE | AL | H | D | 7 | L | 3-8 | 9 | box - pbp - pit | L2 | 3-4 | 4 | 12 | 20 | 2:39 | 40,230 | Luke Hochevar | Derek Lowe (R) | Derek Lowe | Luke Hochevar | None | |
| 2012-04-14 | Sat | CLE | AL | H | N | 8 | W | 9-11 | 10 | box - pbp - pit | W1 | 4-4 | 3 | 10 | 18 | 3:44 | 21,788 | Jonathan Sanchez | Jeanmar Gomez (R) | Luis Valdez | Greg Holland | Chris Perez | |
| 2012-04-15 | Sun | CLE | AL | H | D | 9 | W | 7-13 | 9 | box - pbp - pit | W2 | 5-4 | 2 | 7 | 13 | 3:20 | 21,182 | Luis Mendoza | Ubaldo Jimenez (R) | Ubaldo Jimenez | Luis Mendoza | None | |
| 2012-04-16 | Mon | DET | AL | H | N | 10 | L | 2-3 | 9 | box - pbp - pit | L1 | 5-5 | 3 | 8 | 16 | 2:37 | 14,039 | Danny Duffy | Justin Verlander (R) | Justin Verlander | Danny Duffy | None | |
| 2012-04-17 | Tue | DET | AL | H | N | 11 | L | 1-3 | 9 | box - pbp - pit | L2 | 5-6 | 3 | 9 | 19 | 2:50 | 13,851 | Bruce Chen | Drew Smyly (L) | Octavio Dotel | Bruce Chen | Jose Valverde | |
| 2012-04-18 | Wed | DET | AL | H | N | 12 | L | 3-4 | 9 | box - pbp - pit | L3 | 5-7 | 3 | 10 | 22 | 3:06 | 14,083 | Jonathan Sanchez | Max Scherzer (R) | Max Scherzer | Jose Mijares | Jose Valverde | |
| 2012-04-20 | Fri | TOR | AL | H | N | 13 | L | 3-4 | 9 | box - pbp - pit | L4 | 5-8 | 4 | 12 | 24 | 3:14 | 23,065 | Luke Hochevar | Kyle Drabek (R) | Luis Perez | Greg Holland | Sergio Santos | |
| 2012-04-21 | Sat | TOR | AL | H | N | 14 | L | 5-9 | 9 | box - pbp - pit | L5 | 5-9 | 4 | 12 | 25 | 3:03 | 27,804 | Luis Mendoza | Drew Hutchison (R) | Drew Hutchison | Everett Teaford | None | |
| 2012-04-22 | Sun | TOR | AL | H | D | 15 | L | 3-5 | 9 | box - pbp - pit | L6 | 5-10 | 4 | 12 | 25 | 3:08 | 26,891 | Danny Duffy | Ricky Romero (L) | Ricky Romero | Danny Duffy | Francisco Cordero | |
| 2012-04-23 | Mon | TOR | AL | H | N | 16 | L | 1-4 | 9 | box - pbp - pit | L7 | 5-11 | 4 | 13 | 27 | 2:31 | 13,267 | Bruce Chen | Brandon Morrow (R) | Brandon Morrow | Bruce Chen | Francisco Cordero | |
| 2012-04-24 | Tue | CLE | AL | A | N | 17 | L | 3-4 | 9 | box - pbp - pit | L8 | 5-12 | 4 | 13 | 27 | 3:12 | 9,137 | Jonathan Sanchez | Derek Lowe (R) | Derek Lowe | Jonathan Sanchez | Chris Perez | |
| 2012-04-25 | Wed | CLE | AL | A | N | 18 | W | 8-2 | 9 | box - pbp - pit | W1 | 6-12 | 4 | 13 | 27 | 2:50 | 10,552 | Luke Hochevar | Ubaldo Jimenez (R) | Luke Hochevar | Ubaldo Jimenez | None | |
| 2012-04-26 | Thu | CLE | AL | A | D | 19 | W | 4-2 | 9 | box - pbp - pit | W2 | 7-12 | 4 | 12 | 26 | 3:00 | 9,229 | Luis Mendoza | Josh Tomlin (R) | Luis Mendoza | Josh Tomlin | Jonathan Broxton | |
| 2012-04-27 | Fri | MIN | AL | A | N | 20 | W | 7-6 | 9 | box - pbp - pit | W3 | 8-12 | 4 | 12 | 25 | 3:00 | 33,315 | Everett Teaford | Carl Pavano (R) | Jose Mijares | Brian Duensing | Jonathan Broxton | |
| 2012-04-29 | Sun | MIN | AL | A | D | 21 | L | 4-7 | 9 | box - pbp - pit | L1 | 8-13 | 4 | 12 | 26 | 3:02 | 34,201 | Bruce Chen | Jason Marquis (R) | Jason Marquis | Bruce Chen | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-05-01 | Tue | DET | AL | A | N | 22 | L | 3-9 | 9 | box - pbp - pit | L2 | 8-14 | 4 | 12 | 27 | 2:27 | 30,159 | Luke Hochevar | Rick Porcello (R) | Rick Porcello | Luke Hochevar | None | |
| 2012-05-02 | Wed | DET | AL | A | D | 23 | W | 3-2 | 9 | box - pbp - pit | W1 | 9-14 | 4 | 12 | 27 | 2:52 | 33,187 | Jonathan Sanchez | Justin Verlander (R) | Tim Collins | Joaquin Benoit | Jonathan Broxton | |
| 2012-05-03 | Thu | NYA | AL | H | N | 24 | W | 4-3 | 9 | box - pbp - pit | W2 | 10-14 | 4 | 12 | 25 | 3:20 | 19,590 | Danny Duffy | David Phelps (R) | Danny Duffy | David Phelps | Jonathan Broxton | |
| 2012-05-04 | Fri | NYA | AL | H | N | 25 | L | 2-6 | 9 | box - pbp - pit | L1 | 10-15 | 4 | 12 | 26 | 2:34 | 24,153 | Bruce Chen | CC Sabathia (L) | CC Sabathia | Bruce Chen | None | |
| 2012-05-05 | Sat | NYA | AL | H | N | 26 | W | 5-1 | 9 | box - pbp - pit | W1 | 11-15 | 4 | 12 | 25 | 3:03 | 29,121 | Felipe Paulino | Hiroki Kuroda (R) | Felipe Paulino | Hiroki Kuroda | None | |
| 2012-05-06 | Sun | NYA | AL | H | D | 27 | W | 4-10 | 9 | box - pbp - pit | W2 | 12-15 | 4 | 11 | 23 | 3:06 | 20,434 | Luke Hochevar | Phil Hughes (R) | Phil Hughes | Luke Hochevar | None | |
| 2012-05-07 | Mon | BOS | AL | H | N | 28 | W | 5-11 | 9 | box - pbp - pit | W3 | 13-15 | 4 | 11 | 23 | 3:11 | 19,502 | Jonathan Sanchez | Felix Doubront (L) | Felix Doubront | Jonathan Sanchez | Vicente Padilla | |
| 2012-05-08 | Tue | BOS | AL | H | N | 29 | W | 6-4 | 9 | box - pbp - pit | W4 | 14-15 | 4 | 10 | 21 | 2:52 | 20,524 | Danny Duffy | Daniel Bard (R) | Jose Mijares | Daniel Bard | Jonathan Broxton | |
| 2012-05-09 | Wed | BOS | AL | H | N | 30 | W | 4-3 | 9 | box - pbp - pit | W5 | 15-15 | 4 | 10 | 18 | 2:55 | 18,339 | Bruce Chen | Jon Lester (L) | Bruce Chen | Jon Lester | Jonathan Broxton | |
| 2012-05-11 | Fri | CHA | AL | A | N | 31 | L | 0-5 | 9 | box - pbp - pit | L1 | 15-16 | 4 | 10 | 22 | 2:43 | 19,129 | Felipe Paulino | Gavin Floyd (R) | Gavin Floyd | Felipe Paulino | None | |
| 2012-05-12 | Sat | CHA | AL | A | N | 32 | W | 5-0 | 9 | box - pbp - pit | W1 | 16-16 | 4 | 9 | 16 | 2:46 | 20,066 | Luke Hochevar | Chris Sale (L) | Luke Hochevar | Chris Sale | None | |
| 2012-05-13 | Sun | CHA | AL | A | D | 33 | W | 9-1 | 9 | box - pbp - pit | W2 | 17-16 | 2 | 7 | 14 | 3:21 | 22,636 | Danny Duffy | Philip Humber (R) | Luis Mendoza | Matt Thornton | None | |
| 2012-05-14 | Mon | TEX | AL | A | N | 34 | W | 3-1 | 9 | box - pbp - pit | W3 | 18-16 | 2 | 5 | 11 | 2:50 | 38,702 | Bruce Chen | Scott Feldman (R) | Bruce Chen | Scott Feldman | Jonathan Broxton | |
| 2012-05-15 | Tue | TEX | AL | A | N | 35 | W | 7-4 | 9 | box - pbp - pit | W4 | 19-16 | 1 | 3 | 6 | 2:41 | 37,210 | Vin Mazzaro | Colby Lewis (R) | Vin Mazzaro | Colby Lewis | None | |
| 2012-05-16 | Wed | BAL | AL | H | N | 36 | L | 3-4 | 15 | box - pbp - pit | L1 | 19-17 | 3 | 6 | 11 | 4:10 | 17,949 | Felipe Paulino | Tommy Hunter (R) | Kevin Gregg | Nathan Adcock | Jim Johnson | |
| 2012-05-17 | Thu | BAL | AL | H | D | 37 | L | 3-5 | 9 | box - pbp - pit | L2 | 19-18 | 4 | 9 | 16 | 2:40 | 31,076 | Luke Hochevar | Brian Matusz (L) | Brian Matusz | Luke Hochevar | Jim Johnson | |
| 2012-05-18 | Fri | ARI | NL | H | N | 38 | L | 4-6 | 9 | box - pbp - pit | L3 | 19-19 | 4 | 9 | 17 | 3:06 | 33,694 | Luis Mendoza | Joe Saunders (L) | Brad Ziegler | Kelvin Herrera | J.J. Putz | |
| 2012-05-19 | Sat | ARI | NL | H | N | 39 | W | 7-3 | 9 | box - pbp - pit | W1 | 20-19 | 4 | 8 | 15 | 2:54 | 27,469 | Bruce Chen | Ian Kennedy (R) | Bruce Chen | Ian Kennedy | None | |
| 2012-05-20 | Sun | ARI | NL | H | D | 40 | L | 0-2 | 9 | box - pbp - pit | L1 | 20-20 | 4 | 9 | 18 | 2:37 | 24,234 | Nathan Adcock | Wade Miley (L) | Wade Miley | Nathan Adcock | J.J. Putz | |
| 2012-05-21 | Mon | NYA | AL | A | N | 41 | W | 6-0 | 9 | box - pbp - pit | W1 | 21-20 | 4 | 8 | 15 | 3:10 | 39,229 | Felipe Paulino | Hiroki Kuroda (R) | Felipe Paulino | Hiroki Kuroda | None | |
| 2012-05-22 | Tue | NYA | AL | A | N | 42 | L | 2-3 | 9 | box - pbp - pit | L1 | 21-21 | 4 | 9 | 16 | 2:37 | 37,674 | Luke Hochevar | Phil Hughes (R) | Phil Hughes | Luke Hochevar | Rafael Soriano | |
| 2012-05-23 | Wed | NYA | AL | A | N | 43 | L | 3-8 | 9 | box - pbp - pit | L2 | 21-22 | 4 | 9 | 18 | 2:53 | 40,407 | Will Smith | Andy Pettitte (L) | Andy Pettitte | Will Smith | None | |
| 2012-05-25 | Fri | BAL | AL | A | N | 44 | L | 2-8 | 9 | box - pbp - pit | L3 | 21-23 | 4 | 9 | 18 | 3:00 | 28,954 | Bruce Chen | Jason Hammel (R) | Jason Hammel | Bruce Chen | None | |
| 2012-05-26 | Sat | BAL | AL | A | D | 45 | W | 4-3 | 9 | box - pbp - pit | W1 | 22-23 | 4 | 9 | 17 | 3:14 | 26,714 | Felipe Paulino | Wei-Yin Chen (L) | Greg Holland | Pedro Strop | Jonathan Broxton | |
| 2012-05-27 | Sun | BAL | AL | A | D | 46 | W | 4-2 | 9 | box - pbp - pit | W2 | 23-23 | 4 | 8 | 16 | 3:05 | 33,919 | Luke Hochevar | Brian Matusz (L) | Tim Collins | Brian Matusz | Jonathan Broxton | |
| 2012-05-28 | Mon | CLE | AL | A | D | 47 | L | 5-8 | 9 | box - pbp - pit | L1 | 23-24 | 4 | 8 | 17 | 3:01 | 25,377 | Nathan Adcock | Josh Tomlin (R) | Josh Tomlin | Nathan Adcock | Chris Perez | |
| 2012-05-29 | Tue | CLE | AL | A | N | 48 | W | 8-2 | 9 | box - pbp - pit | W1 | 24-24 | 3 | 7 | 15 | 2:44 | 14,253 | Will Smith | Justin Masterson (R) | Will Smith | Justin Masterson | None | |
| 2012-05-30 | Wed | CLE | AL | A | D | 49 | W | 6-3 | 9 | box - pbp - pit | W2 | 25-24 | 3 | 7 | 14 | 3:28 | 17,112 | Bruce Chen | Jeanmar Gomez (R) | Bruce Chen | Jeanmar Gomez | Jonathan Broxton | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-06-01 | Fri | OAK | AL | H | N | 50 | W | 2-0 | 9 | box - pbp - pit | W3 | 26-24 | 3 | 7 | 14 | 2:24 | 29,527 | Felipe Paulino | Bartolo Colon (R) | Felipe Paulino | Bartolo Colon | Jonathan Broxton | |
| 2012-06-02 | Sat | OAK | AL | H | D | 51 | L | 3-9 | 9 | box - pbp - pit | L1 | 26-25 | 3 | 7 | 14 | 3:09 | 26,276 | Luke Hochevar | Brandon McCarthy (R) | Brandon McCarthy | Luke Hochevar | None | |
| 2012-06-03 | Sun | OAK | AL | H | D | 52 | W | 2-0 | 9 | box - pbp - pit | W1 | 27-25 | 3 | 7 | 14 | 2:37 | 21,111 | Vin Mazzaro | Tommy Milone (L) | Vin Mazzaro | Tom Milone | Jonathan Broxton | |
| 2012-06-04 | Mon | MIN | AL | H | N | 53 | W | 7-10 | 9 | box - pbp - pit | W2 | 28-25 | 3 | 7 | 14 | 3:07 | 16,531 | Will Smith | Cole Devries (R) | Cole De Vries | Will Smith | Matt Capps | |
| 2012-06-05 | Tue | MIN | AL | H | N | 54 | W | 1-0 | 9 | box - pbp - pit | W3 | 29-25 | 3 | 7 | 13 | 2:25 | 23,934 | Bruce Chen | Francisco Liriano (L) | Bruce Chen | Francisco Liriano | Jonathan Broxton | |
| 2012-06-06 | Wed | MIN | AL | H | N | 55 | L | 2-4 | 9 | box - pbp - pit | L1 | 29-26 | 3 | 7 | 14 | 3:04 | 18,386 | Felipe Paulino | Nick Blackburn (R) | Nick Blackburn | Luis Mendoza | Matt Capps | |
| 2012-06-08 | Fri | PIT | NL | A | N | 56 | L | 2-4 | 9 | box - pbp - pit | L2 | 29-27 | 3 | 7 | 14 | 2:32 | 36,069 | Luke Hochevar | Erik Bedard (L) | Erik Bedard | Luke Hochevar | Joel Hanrahan | |
| 2012-06-09 | Sat | PIT | NL | A | N | 57 | L | 3-5 | 9 | box - pbp - pit | L3 | 29-28 | 3 | 8 | 15 | 3:14 | 39,312 | Vin Mazzaro | James McDonald (R) | Jared Hughes | Vin Mazzaro | Joel Hanrahan | |
| 2012-06-10 | Sun | PIT | NL | A | D | 58 | L | 2-3 | 9 | box - pbp - pit | L4 | 29-29 | 3 | 8 | 16 | 2:55 | 25,752 | Bruce Chen | AJ Burnett (R) | A.J. Burnett | Bruce Chen | Jason Grilli | |
| 2012-06-12 | Tue | MIL | NL | H | N | 59 | W | 2-1 | 9 | box - pbp - pit | W1 | 30-29 | 3 | 7 | 14 | 2:36 | 24,258 | Luis Mendoza | Zack Greinke (R) | Greg Holland | Francisco Rodriguez | Jonathan Broxton | |
| 2012-06-13 | Wed | MIL | NL | H | N | 60 | W | 4-3 | 11 | box - pbp - pit | W2 | 31-29 | 3 | 7 | 14 | 3:27 | 17,885 | Jonathan Sanchez | Randy Wolf (L) | Tim Collins | Kameron Loe | None | |
| 2012-06-14 | Thu | MIL | NL | H | N | 61 | W | 4-3 | 9 | box - pbp - pit | W3 | 32-29 | 3 | 7 | 13 | 2:48 | 21,869 | Luke Hochevar | Shaun Marcum (R) | Tim Collins | John Axford | None | |
| 2012-06-15 | Fri | SLN | NL | A | N | 62 | W | 3-2 | 9 | box - pbp - pit | W4 | 33-29 | 3 | 7 | 13 | 2:39 | 42,001 | Vin Mazzaro | Kyle Lohse (R) | Vin Mazzaro | Kyle Lohse | Jonathan Broxton | |
| 2012-06-16 | Sat | SLN | NL | A | D | 63 | W | 7-10 | 9 | box - pbp - pit | W5 | 34-29 | 3 | 7 | 13 | 3:38 | 42,018 | Bruce Chen | Joe Kelly (R) | Mitchell Boggs | Tim Collins | Jason Motte | |
| 2012-06-17 | Sun | SLN | NL | A | D | 64 | W | 5-3 | 15 | box - pbp - pit | W6 | 35-29 | 2 | 6 | 11 | 5:00 | 41,680 | Luis Mendoza | Adam Wainwright (R) | Jonathan Broxton | Eduardo Sanchez | None | |
| 2012-06-18 | Mon | HOU | NL | A | N | 65 | L | 7-9 | 9 | box - pbp - pit | L1 | 35-30 | 2 | 6 | 13 | 3:04 | 15,436 | Jonathan Sanchez | J.A. Happ (L) | J.A. Happ | Jonathan Sanchez | Xavier Cedeno | |
| 2012-06-19 | Tue | HOU | NL | A | N | 66 | W | 2-0 | 9 | box - pbp - pit | W1 | 36-30 | 2 | 6 | 11 | 2:31 | 18,098 | Luke Hochevar | Wandy Rodriguez (L) | Luke Hochevar | Wandy Rodriguez | Jonathan Broxton | |
| 2012-06-20 | Wed | HOU | NL | A | D | 67 | W | 2-1 | 9 | box - pbp - pit | W2 | 37-30 | 2 | 6 | 11 | 2:41 | 30,687 | Bruce Chen | Jordan Lyles (R) | Bruce Chen | Jordan Lyles | Jonathan Broxton | |
| 2012-06-22 | Fri | SLN | NL | H | N | 68 | W | 4-11 | 9 | box - pbp - pit | W3 | 38-30 | 1 | 5 | 10 | 3:05 | 37,902 | Vin Mazzaro | Joe Kelly (R) | Joe Kelly | Vin Mazzaro | None | |
| 2012-06-23 | Sat | SLN | NL | H | D | 69 | L | 2-8 | 9 | box - pbp - pit | L1 | 38-31 | 2 | 6 | 11 | 2:58 | 37,240 | Luis Mendoza | Adam Wainwright (R) | Adam Wainwright | Luis Mendoza | None | |
| 2012-06-24 | Sun | SLN | NL | H | D | 70 | W | 8-11 | 9 | box - pbp - pit | W1 | 39-31 | 2 | 6 | 11 | 3:08 | 29,063 | Jonathan Sanchez | Lance Lynn (R) | Victor Marte | Tim Collins | None | |
| 2012-06-25 | Mon | TBA | AL | H | N | 71 | W | 8-0 | 9 | box - pbp - pit | W2 | 40-31 | 1 | 3 | 7 | 2:17 | 20,200 | Luke Hochevar | Alex Cobb (R) | Luke Hochevar | Alex Cobb | None | |
| 2012-06-26 | Tue | TBA | AL | H | N | 72 | W | 8-2 | 9 | box - pbp - pit | W3 | 41-31 | 1 | 2 | 5 | 2:30 | 25,982 | Bruce Chen | Chris Archer (R) | Bruce Chen | Chris Archer | None | |
| 2012-06-27 | Wed | TBA | AL | H | D | 73 | W | 5-4 | 9 | box - pbp - pit | W4 | 42-31 | 1 | 2 | 5 | 3:01 | 19,228 | Everett Teaford | Matt Moore (L) | Aaron Crow | Burke Badenhop | Jonathan Broxton | |
| 2012-06-29 | Fri | MIN | AL | A | N | 74 | W | 4-3 | 9 | box - pbp - pit | W5 | 43-31 | 1 | 2 | 2 | 2:50 | 33,359 | Luis Mendoza | Brian Duensing (L) | Luis Mendoza | Brian Duensing | Jonathan Broxton | |
| 2012-06-30 | Sat | MIN | AL | A | D | 75 | L | 2-7 | 9 | box - pbp - pit | L1 | 43-33 | 1 | 3 | 6 | 2:45 | 37,694 | Jonathan Sanchez | Scott Diamond (L) | Scott Diamond | Jonathan Sanchez | None | |
| 2012-06-30 | Sat | MIN | AL | A | N | 76 | L | 1-5 | 9 | box - pbp - pit | L2 | 43-33 | 1 | 3 | 6 | 2:43 | 37,629 | Luke Hochevar | Cole Devries (R) | Cole De Vries | Luke Hochevar | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-07-01 | Sun | MIN | AL | A | D | 77 | W | 8-10 | 9 | box - pbp - pit | W1 | 44-33 | 1 | 2 | 5 | 3:05 | 37,819 | Bruce Chen | Francisco Liriano (L) | Jeff Gray | Bruce Chen | None | |
| 2012-07-02 | Mon | TOR | AL | A | N | 78 | L | 11-3 | 9 | box - pbp - pit | L1 | 44-34 | 1 | 3 | 6 | 2:36 | 17,127 | Everett Teaford | Ricky Romero (L) | Everett Teaford | Ricky Romero | None | |
| 2012-07-03 | Tue | TOR | AL | A | N | 79 | L | 3-6 | 9 | box - pbp - pit | L2 | 44-35 | 1 | 3 | 7 | 2:30 | 15,516 | Vin Mazzaro | Brett Cecil (L) | Brett Cecil | Vin Mazzaro | Casey Janssen | |
| 2012-07-04 | Wed | TOR | AL | A | N | 80 | L | 1-4 | 9 | box - pbp - pit | L3 | 44-36 | 1 | 4 | 8 | 2:45 | 17,831 | Luis Mendoza | Carlos Villanueva (R) | Carlos Villanueva | Luis Mendoza | Casey Janssen | |
| 2012-07-05 | Thu | TOR | AL | A | N | 81 | W | 9-6 | 9 | box - pbp - pit | W1 | 45-36 | 1 | 3 | 6 | 3:16 | 20,598 | Luke Hochevar | Henderson Alvarez (R) | Luke Hochevar | Henderson Alvarez | Jonathan Broxton | |
| 2012-07-06 | Fri | DET | AL | A | N | 82 | L | 2-4 | 9 | box - pbp - pit | L1 | 45-37 | 2 | 5 | 10 | 2:56 | 39,144 | Jonathan Sanchez | Drew Smyly (L) | Drew Smyly | Jonathan Sanchez | Jose Valverde | |
| 2012-07-07 | Sat | DET | AL | A | D | 83 | L | 7-8 | 9 | box - pbp - pit | L2 | 45-38 | 2 | 5 | 11 | 3:00 | 39,392 | Bruce Chen | Doug Fister (R) | Doug Fister | Bruce Chen | None | |
| 2012-07-08 | Sun | DET | AL | A | D | 84 | L | 1-7 | 9 | box - pbp - pit | L3 | 45-39 | 3 | 7 | 13 | 2:41 | 36,693 | Everett Teaford | Max Scherzer (R) | Max Scherzer | Everett Teaford | None | |
| 2012-07-13 | Fri | CHA | AL | H | N | 85 | L | 8-9 | 14 | box - pbp - pit | L4 | 45-40 | 3 | 7 | 14 | 5:23 | 32,744 | Bruce Chen | Jose Quintana (L) | Dylan Axelrod | Everett Teaford | None | |
| 2012-07-14 | Sat | CHA | AL | H | N | 86 | W | 6-3 | 9 | box - pbp - pit | W1 | 46-40 | 3 | 7 | 14 | 2:56 | 24,998 | Luke Hochevar | Jake Peavy (R) | Greg Holland | Jake Peavy | Jonathan Broxton | |
| 2012-07-15 | Sun | CHA | AL | H | D | 87 | L | 1-2 | 9 | box - pbp - pit | L1 | 46-41 | 3 | 7 | 14 | 2:52 | 25,714 | Luis Mendoza | Chris Sale (L) | Chris Sale | Luis Mendoza | Addison Reed | |
| 2012-07-16 | Mon | SEA | AL | H | N | 88 | L | 4-9 | 9 | box - pbp - pit | L2 | 46-42 | 4 | 8 | 15 | 2:59 | 16,697 | Jonathan Sanchez | Jason Vargas (L) | Jason Vargas | Jonathan Sanchez | None | |
| 2012-07-17 | Tue | SEA | AL | H | N | 89 | L | 6-9 | 9 | box - pbp - pit | L3 | 46-43 | 4 | 8 | 15 | 3:09 | 15,769 | Ryan Verdugo | Blake Beavan (R) | Blake Beavan | Ryan Verdugo | Tom Wilhelmsen | |
| 2012-07-18 | Wed | SEA | AL | H | N | 90 | W | 8-7 | 9 | box - pbp - pit | W1 | 47-43 | 3 | 7 | 14 | 3:03 | 17,312 | Bruce Chen | Kevin Millwood (R) | Greg Holland | Josh Kinney | None | |
| 2012-07-19 | Thu | SEA | AL | H | D | 91 | L | 1-6 | 9 | box - pbp - pit | L1 | 47-44 | 3 | 8 | 15 | 2:31 | 16,706 | Will Smith | Felix Hernandez (R) | Felix Hernandez | Will Smith | None | |
| 2012-07-20 | Fri | MIN | AL | H | N | 92 | L | 1-2 | 11 | box - pbp - pit | L2 | 47-45 | 4 | 10 | 17 | 3:23 | 25,719 | Luke Hochevar | Nick Blackburn (R) | Casey Fien | Jonathan Broxton | Glen Perkins | |
| 2012-07-21 | Sat | MIN | AL | H | N | 93 | W | 7-3 | 9 | box - pbp - pit | W1 | 48-45 | 3 | 9 | 16 | 3:02 | 26,747 | Luis Mendoza | Scott Diamond (L) | Luis Mendoza | Scott Diamond | Aaron Crow | |
| 2012-07-22 | Sun | MIN | AL | H | D | 94 | L | 5-7 | 9 | box - pbp - pit | L1 | 48-46 | 3 | 9 | 16 | 2:47 | 23,252 | Jeremy Guthrie | Samuel Deduno (R) | Samuel Deduno | Jeremy Guthrie | None | |
| 2012-07-23 | Mon | ANA | AL | A | N | 95 | L | 3-6 | 9 | box - pbp - pit | L2 | 48-47 | 4 | 10 | 17 | 3:21 | 35,047 | Bruce Chen | CJ Wilson (L) | Kevin Jepsen | Greg Holland | Scott Downs | |
| 2012-07-24 | Tue | ANA | AL | A | N | 96 | W | 4-1 | 9 | box - pbp - pit | W1 | 49-47 | 4 | 10 | 17 | 2:54 | 35,051 | Will Smith | Garrett Richards (R) | Will Smith | Garrett Richards | Jonathan Broxton | |
| 2012-07-25 | Wed | ANA | AL | A | D | 97 | W | 6-11 | 9 | box - pbp - pit | W2 | 50-47 | 3 | 9 | 14 | 3:07 | 39,107 | Luke Hochevar | Jered Weaver (R) | Jered Weaver | Luke Hochevar | None | |
| 2012-07-26 | Thu | SEA | AL | A | N | 98 | L | 1-4 | 9 | box - pbp - pit | L1 | 50-48 | 4 | 10 | 16 | 2:31 | 15,014 | Luis Mendoza | Jason Vargas (L) | Jason Vargas | Luis Mendoza | Tom Wilhelmsen | |
| 2012-07-27 | Fri | SEA | AL | A | N | 99 | L | 1-6 | 9 | box - pbp - pit | L2 | 50-49 | 4 | 10 | 16 | 2:30 | 14,953 | Jeremy Guthrie | Blake Beavan (R) | Blake Beavan | Jeremy Guthrie | None | |
| 2012-07-28 | Sat | SEA | AL | A | D | 100 | L | 3-4 | 9 | box - pbp - pit | L3 | 50-50 | 4 | 10 | 17 | 2:42 | 32,111 | Bruce Chen | Kevin Millwood (R) | Kevin Millwood | Bruce Chen | Tom Wilhelmsen | |
| 2012-07-29 | Sun | SEA | AL | A | D | 101 | L | 6-7 | 9 | box - pbp - pit | L4 | 50-51 | 4 | 10 | 18 | 3:00 | 19,402 | Will Smith | Felix Hernandez (R) | Oliver Perez | Jose Mijares | Tom Wilhelmsen | |
| 2012-07-31 | Tue | CLE | AL | H | N | 102 | W | 8-3 | 9 | box - pbp - pit | W1 | 51-51 | 4 | 10 | 18 | 2:46 | 18,569 | Luke Hochevar | Derek Lowe (R) | Luke Hochevar | Derek Lowe | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-08-01 | Wed | CLE | AL | H | N | 103 | W | 5-2 | 9 | box - pbp - pit | W2 | 52-51 | 3 | 9 | 17 | 2:31 | 17,033 | Luis Mendoza | Zach McAllister (R) | Luis Mendoza | Zach McAllister | Greg Holland | |
| 2012-08-02 | Thu | CLE | AL | H | N | 104 | W | 7-6 | 11 | box - pbp - pit | W3 | 53-51 | 3 | 9 | 16 | 3:41 | 15,135 | Bruce Chen | Corey Kluber (R) | Aaron Crow | Esmil Rogers | None | |
| 2012-08-03 | Fri | TEX | AL | H | N | 105 | L | 3-5 | 9 | box - pbp - pit | L1 | 53-52 | 3 | 9 | 16 | 2:58 | 26,889 | Jeremy Guthrie | Matt Harrison (L) | Matt Harrison | Jeremy Guthrie | Alexi Ogando | |
| 2012-08-04 | Sat | TEX | AL | H | N | 106 | L | 2-4 | 9 | box - pbp - pit | L2 | 53-53 | 3 | 9 | 17 | 2:41 | 28,724 | Will Smith | Scott Feldman (R) | Scott Feldman | Will Smith | Alexi Ogando | |
| 2012-08-05 | Sun | TEX | AL | H | D | 107 | W | 7-6 | 10 | box - pbp - pit | W1 | 54-53 | 3 | 9 | 16 | 3:26 | 22,007 | Luke Hochevar | Derek Holland (L) | Greg Holland | Michael Kirkman | None | |
| 2012-08-06 | Mon | CHA | AL | A | N | 108 | L | 2-4 | 9 | box - pbp - pit | L1 | 54-54 | 4 | 10 | 18 | 2:17 | 30,097 | Luis Mendoza | Chris Sale (L) | Chris Sale | Luis Mendoza | Addison Reed | |
| 2012-08-07 | Tue | CHA | AL | A | N | 109 | W | 5-2 | 9 | box - pbp - pit | W1 | 55-54 | 3 | 9 | 17 | 2:34 | 27,194 | Bruce Chen | Jake Peavy (R) | Bruce Chen | Jake Peavy | Greg Holland | |
| 2012-08-08 | Wed | CHA | AL | A | N | 110 | W | 2-1 | 9 | box - pbp - pit | W2 | 56-54 | 3 | 9 | 17 | 2:37 | 25,151 | Jeremy Guthrie | Jose Quintana (L) | Jeremy Guthrie | Jose Quintana | Greg Holland | |
| 2012-08-09 | Thu | BAL | AL | A | N | 111 | W | 8-2 | 9 | box - pbp - pit | W3 | 57-54 | 3 | 9 | 15 | 2:40 | 21,226 | Will Smith | Wei-Yin Chen (L) | Will Smith | Wei-Yin Chen | None | |
| 2012-08-10 | Fri | BAL | AL | A | N | 112 | L | 1-7 | 9 | box - pbp - pit | L1 | 57-55 | 3 | 9 | 16 | 2:31 | 17,277 | Luke Hochevar | Miguel Gonzalez (R) | Miguel Gonzalez | Luke Hochevar | None | |
| 2012-08-11 | Sat | BAL | AL | A | N | 113 | W | 7-3 | 9 | box - pbp - pit | W1 | 58-55 | 3 | 9 | 15 | 2:59 | 40,456 | Luis Mendoza | Chris Tillman (R) | Luis Mendoza | Chris Tillman | None | |
| 2012-08-12 | Sun | BAL | AL | A | D | 114 | L | 3-5 | 9 | box - pbp - pit | L1 | 58-56 | 3 | 9 | 16 | 2:44 | 20,935 | Bruce Chen | Tommy Hunter (R) | Luis Ayala | Bruce Chen | Jim Johnson | |
| 2012-08-14 | Tue | OAK | AL | H | N | 115 | W | 5-0 | 9 | box - pbp - pit | W1 | 59-56 | 3 | 8 | 15 | 2:23 | 16,107 | Jeremy Guthrie | Jarrod Parker (R) | Jeremy Guthrie | Jarrod Parker | None | |
| 2012-08-14 | Tue | OAK | AL | H | N | 115 | W | 5-0 | 9 | box - pbp - pit | W2 | 59-56 | 3 | 8 | 15 | 2:23 | 16,107 | Jeremy Guthrie | Kyle Parker (R) | Jeremy Guthrie | Jarrod Parker | None | |
| 2012-08-15 | Wed | OAK | AL | H | N | 116 | W | 3-2 | 9 | box - pbp - pit | W3 | 60-56 | 3 | 8 | 14 | 2:35 | 15,591 | Will Smith | Brandon McCarthy (R) | Will Smith | Brandon McCarthy | Greg Holland | |
| 2012-08-16 | Thu | OAK | AL | H | N | 117 | L | 0-3 | 9 | box - pbp - pit | L1 | 60-57 | 3 | 9 | 14 | 2:57 | 14,345 | Luke Hochevar | Dan Straily (R) | Dan Straily | Luke Hochevar | Grant Balfour | |
| 2012-08-17 | Fri | CHA | AL | H | N | 118 | W | 4-2 | 9 | box - pbp - pit | W1 | 61-57 | 3 | 7 | 14 | 2:31 | 22,169 | Luis Mendoza | Chris Sale (L) | Luis Mendoza | Chris Sale | Greg Holland | |
| 2012-08-18 | Sat | CHA | AL | H | N | 119 | W | 9-4 | 9 | box - pbp - pit | W2 | 62-57 | 3 | 9 | 14 | 2:59 | 23,858 | Bruce Chen | Jake Peavy (R) | Bruce Chen | Jake Peavy | None | |
| 2012-08-19 | Sun | CHA | AL | H | D | 120 | W | 5-2 | 9 | box - pbp - pit | W3 | 63-57 | 3 | 8 | 12 | 2:43 | 22,401 | Jeremy Guthrie | Jose Quintana (L) | Greg Holland | Jesse Crain | None | |
| 2012-08-20 | Mon | TBA | AL | A | N | 121 | L | 1-5 | 9 | box - pbp - pit | L1 | 63-58 | 3 | 7 | 13 | 2:46 | 9,913 | Will Smith | Jeremy Hellickson (R) | Jeremy Hellickson | Will Smith | None | |
| 2012-08-21 | Tue | TBA | AL | A | N | 122 | W | 1-0 | 10 | box - pbp - pit | W1 | 64-58 | 3 | 8 | 12 | 2:46 | 10,877 | Luke Hochevar | David Price (L) | Kelvin Herrera | Joel Peralta | Greg Holland | |
| 2012-08-22 | Wed | TBA | AL | A | D | 123 | L | 3-5 | 9 | box - pbp - pit | L1 | 64-59 | 3 | 8 | 13 | 2:54 | 11,892 | Luis Mendoza | James Shields (R) | James Shields | Luis Mendoza | Fernando Rodney | |
| 2012-08-24 | Fri | BOS | AL | A | N | 124 | L | 3-4 | 9 | box - pbp - pit | L2 | 64-60 | 3 | 8 | 13 | 2:54 | 37,228 | Bruce Chen | Jon Lester (L) | Jon Lester | Kelvin Herrera | Andrew Bailey | |
| 2012-08-25 | Sat | BOS | AL | A | N | 125 | L | 10-9 | 12 | box - pbp - pit | L3 | 64-61 | 3 | 9 | 14 | 4:31 | 37,103 | Jeremy Guthrie | Aaron Cook (R) | Francisley Bueno | Junichi Tazawa | Greg Holland | |
| 2012-08-26 | Sun | BOS | AL | A | D | 126 | L | 6-8 | 9 | box - pbp - pit | L4 | 64-62 | 3 | 9 | 15 | 3:36 | 37,188 | Will Smith | Felix Doubront (L) | Pedro Beato | Will Smith | Mark Melancon | |
| 2012-08-27 | Mon | BOS | AL | A | D | 127 | L | 1-5 | 9 | box - pbp - pit | L5 | 64-63 | 3 | 9 | 15 | 2:34 | 37,506 | Luke Hochevar | Daisuke Matsuzaka (R) | Daisuke Matsuzaka | Luke Hochevar | None | |
| 2012-08-28 | Tue | DET | AL | H | N | 128 | W | 9-8 | 9 | box - pbp - pit | W1 | 65-63 | 3 | 9 | 15 | 3:30 | 13,601 | Luis Mendoza | Justin Verlander (R) | Aaron Crow | Brayan Villarreal | Greg Holland | |
| 2012-08-29 | Wed | DET | AL | H | N | 129 | W | 1-0 | 9 | box - pbp - pit | W2 | 66-63 | 3 | 9 | 14 | 2:25 | 13,024 | Bruce Chen | Anibal Sanchez (R) | Bruce Chen | Anibal Sanchez | Greg Holland | |
| 2012-08-30 | Thu | DET | AL | H | N | 130 | W | 2-1 | 9 | box - pbp - pit | W3 | 67-63 | 3 | 9 | 14 | 2:41 | 12,997 | Jeremy Guthrie | Rick Porcello (R) | Jeremy Guthrie | Rick Porcello | Kelvin Herrera | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-09-01 | Sat | MIN | AL | H | D | 131 | L | 1-3 | 9 | box - pbp - pit | L1 | 67-65 | 3 | 9 | 14 | 2:31 | 0 | Will Smith | Cole Devries (R) | Cole De Vries | Will Smith | Glen Perkins | |
| 2012-09-01 | Sat | MIN | AL | H | N | 132 | L | 7-8 | 9 | box - pbp - pit | L2 | 67-65 | 3 | 9 | 14 | 3:07 | 23,189 | Luke Hochevar | Liam Hendriks (R) | Anthony Swarzak | Luke Hochevar | Glen Perkins | |
| 2012-09-02 | Sun | MIN | AL | H | D | 133 | W | 6-4 | 9 | box - pbp - pit | W1 | 68-65 | 3 | 9 | 14 | 2:55 | 23,641 | Luis Mendoza | Esmerling Vasquez (R) | Tim Collins | Esmerling Vasquez | Greg Holland | |
| 2012-09-03 | Mon | TEX | AL | H | D | 134 | L | 4-8 | 9 | box - pbp - pit | L1 | 68-66 | 3 | 9 | 15 | 2:40 | 22,207 | Bruce Chen | Yu Darvish (R) | Yu Darvish | Bruce Chen | None | |
| 2012-09-04 | Tue | TEX | AL | H | N | 135 | W | 6-3 | 9 | box - pbp - pit | W1 | 69-66 | 3 | 9 | 14 | 2:32 | 12,462 | Jeremy Guthrie | Matt Harrison (L) | Jeremy Guthrie | Matt Harrison | Greg Holland | |
| 2012-09-05 | Wed | TEX | AL | H | N | 136 | L | 6-7 | 9 | box - pbp - pit | L1 | 69-67 | 3 | 9 | 15 | 2:58 | 13,354 | Everett Teaford | Ryan Dempster (R) | Ryan Dempster | Everett Teaford | Joe Nathan | |
| 2012-09-06 | Thu | TEX | AL | H | N | 137 | L | 4-5 | 10 | box - pbp - pit | L2 | 69-68 | 3 | 9 | 15 | 3:20 | 15,332 | Luke Hochevar | Scott Feldman (R) | Mike Adams | Greg Holland | Joe Nathan | |
| 2012-09-07 | Fri | CHA | AL | A | N | 138 | W | 7-5 | 9 | box - pbp - pit | W1 | 70-68 | 3 | 9 | 15 | 3:02 | 26,660 | Luis Mendoza | Francisco Liriano (L) | Kelvin Herrera | Addison Reed | Greg Holland | |
| 2012-09-08 | Sat | CHA | AL | A | D | 139 | L | 4-5 | 9 | box - pbp - pit | L1 | 70-69 | 3 | 9 | 15 | 2:48 | 26,227 | Bruce Chen | Chris Sale (L) | Chris Sale | Bruce Chen | Addison Reed | |
| 2012-09-09 | Sun | CHA | AL | A | D | 140 | W | 2-1 | 10 | box - pbp - pit | W1 | 71-69 | 3 | 9 | 15 | 3:30 | 19,356 | Jeremy Guthrie | Hector Santiago (L) | Kelvin Herrera | Brett Myers | Greg Holland | |
| 2012-09-11 | Tue | MIN | AL | A | N | 141 | W | 9-1 | 9 | box - pbp - pit | W2 | 72-69 | 3 | 9 | 14 | 2:56 | 28,993 | Will Smith | Scott Diamond (L) | Will Smith | Scott Diamond | None | |
| 2012-09-12 | Wed | MIN | AL | A | N | 142 | L | 10-5 | 9 | box - pbp - pit | L1 | 72-70 | 3 | 9 | 15 | 3:25 | 28,139 | Luke Hochevar | P.J. Walters (R) | Luke Hochevar | P.J. Walters | None | |
| 2012-09-13 | Thu | MIN | AL | A | N | 143 | L | 3-4 | 10 | box - pbp - pit | L2 | 72-71 | 3 | 9 | 16 | 3:13 | 28,669 | Luis Mendoza | Liam Hendriks (R) | Glen Perkins | Francisley Bueno | None | |
| 2012-09-14 | Fri | ANA | AL | H | N | 144 | L | 7-9 | 9 | box - pbp - pit | L3 | 72-72 | 3 | 9 | 16 | 3:42 | 27,586 | Bruce Chen | CJ Wilson (L) | Jordan Walden | Tim Collins | Ernesto Frieri | |
| 2012-09-15 | Sat | ANA | AL | H | N | 145 | W | 3-2 | 9 | box - pbp - pit | W1 | 73-72 | 3 | 9 | 15 | 2:23 | 23,027 | Jeremy Guthrie | Zack Greinke (R) | Kelvin Herrera | Ernesto Frieri | None | |
| 2012-09-16 | Sun | ANA | AL | H | D | 146 | L | 3-4 | 9 | box - pbp - pit | L1 | 73-73 | 3 | 9 | 15 | 2:43 | 24,979 | Will Smith | Dan Haren (R) | Dan Haren | Will Smith | Kevin Jepsen | |
| 2012-09-18 | Tue | CHA | AL | H | N | 147 | L | 2-3 | 9 | box - pbp - pit | L2 | 73-74 | 3 | 9 | 16 | 2:12 | 14,420 | Luke Hochevar | Gavin Floyd (R) | Gavin Floyd | Luke Hochevar | Addison Reed | |
| 2012-09-19 | Wed | CHA | AL | H | N | 148 | W | 3-0 | 9 | box - pbp - pit | W1 | 74-74 | 3 | 9 | 17 | 2:51 | 15,120 | Bruce Chen | Chris Sale (L) | Bruce Chen | Chris Sale | Greg Holland | |
| 2012-09-20 | Thu | CHA | AL | H | N | 149 | W | 4-3 | 9 | box - pbp - pit | W2 | 75-74 | 3 | 9 | 17 | 2:41 | 14,710 | Jeremy Guthrie | Francisco Liriano (L) | Greg Holland | Jesse Crain | None | |
| 2012-09-21 | Fri | CLE | AL | H | N | 150 | W | 6-3 | 9 | box - pbp - pit | W3 | 76-74 | 3 | 9 | 16 | 2:41 | 22,805 | Luis Mendoza | Justin Masterson (R) | Luis Mendoza | Justin Masterson | Greg Holland | |
| 2012-09-22 | Sat | CLE | AL | H | N | 151 | W | 5-3 | 9 | box - pbp - pit | W4 | 77-74 | 3 | 9 | 14 | 2:47 | 24,304 | Will Smith | Ubaldo Jimenez (R) | Will Smith | Ubaldo Jimenez | Kelvin Herrera | |
| 2012-09-23 | Sun | CLE | AL | H | D | 152 | W | 4-15 | 9 | box - pbp - pit | W5 | 78-74 | 3 | 9 | 15 | 3:17 | 22,960 | Jake Odorizzi | David Huff (L) | David Huff | Jake Odorizzi | None | |
| 2012-09-24 | Mon | DET | AL | A | N | 153 | L | 2-6 | 9 | box - pbp - pit | L1 | 78-75 | 3 | 9 | 15 | 2:34 | 31,521 | Luke Hochevar | Justin Verlander (R) | Justin Verlander | Luke Hochevar | None | |
| 2012-09-25 | Tue | DET | AL | A | N | 154 | L | 0-2 | 9 | box - pbp - pit | L2 | 78-76 | 3 | 9 | 16 | 2:13 | 29,048 | Bruce Chen | Anibal Sanchez (R) | Anibal Sanchez | Bruce Chen | None | |
| 2012-09-26 | Wed | DET | AL | A | N | 155 | L | 4-5 | 9 | box - pbp - pit | L3 | 78-77 | 3 | 9 | 16 | 2:39 | 32,360 | Jeremy Guthrie | Rick Porcello (R) | Joaquin Benoit | Kelvin Herrera | Jose Valverde | |
| 2012-09-27 | Thu | DET | AL | A | D | 156 | L | 4-5 | 9 | box - pbp - pit | L4 | 78-78 | 3 | 9 | 17 | 2:23 | 33,019 | Luis Mendoza | Doug Fister (R) | Joaquin Benoit | Tim Collins | None | |
| 2012-09-28 | Fri | CLE | AL | A | N | 157 | L | 5-8 | 9 | box - pbp - pit | L5 | 78-79 | 3 | 9 | 16 | 3:00 | 14,850 | Will Smith | David Huff (L) | David Huff | Will Smith | Chris Perez | |
| 2012-09-29 | Sat | CLE | AL | A | N | 158 | W | 7-6 | 14 | box - pbp - pit | W1 | 79-79 | 3 | 9 | 15 | 4:52 | 17,109 | Jake Odorizzi | Jeanmar Gomez (R) | Vin Mazzaro | Scott Maine | Kelvin Herrera | |
| 2012-09-30 | Sun | CLE | AL | A | D | 159 | W | 3-15 | 9 | box - pbp - pit | W2 | 80-79 | 3 | 9 | 16 | 3:02 | 18,099 | Luke Hochevar | Zach McAllister (R) | Zach McAllister | Luke Hochevar | None | |
| Game Date | Day | Opp | Lg | H/A | D/N | G | W/L | Result | Inn | Boxscores | Strk | Record | Div-Rk | Lg-Rk | MLB-Rk | Time | Att | Ballpark | Starting Pitcher | Opposing Pitcher | Winning Pitcher | Losing Pitcher | Save Pitcher |
| 2012-10-01 | Mon | DET | AL | H | N | 160 | L | 3-6 | 9 | box - pbp - pit | L1 | 80-80 | 3 | 9 | 16 | 2:55 | 15,312 | Bruce Chen | Rick Porcello (R) | Rick Porcello | Bruce Chen | Jose Valverde | |
| 2012-10-02 | Tue | DET | AL | H | N | 161 | W | 4-2 | 9 | box - pbp - pit | W1 | 81-80 | 3 | 9 | 15 | 2:34 | 14,283 | Jeremy Guthrie | Doug Fister (R) | Jeremy Guthrie | Doug Fister | Greg Holland | |
| 2012-10-03 | Wed | DET | AL | H | N | 162 | L | 0-1 | 9 | box - pbp - pit | L1 | 81-81 | 3 | 9 | 15 | 2:59 | 30,383 | Luis Mendoza | Max Scherzer (R) | Luis Marte | Luis Mendoza | Luke Putkonen |
Team Splits | Top |
| Category | GP | W | L | Wpct | RF | RA | Diff |
| Season Total | 163 | 82 | 81 | .503 | 681 | 746 | -65 |
| Home Games | 82 | 46 | 36 | .561 | 346 | 382 | -36 |
| Away Games | 81 | 36 | 45 | .444 | 335 | 364 | -29 |
| Night Games | 112 | 58 | 54 | .518 | 473 | 455 | +18 |
| Day Games | 51 | 24 | 27 | .471 | 208 | 291 | -83 |
| March/April | 21 | 8 | 13 | .381 | 83 | 102 | -19 |
| May | 28 | 17 | 11 | .607 | 117 | 117 | 0 |
| June | 27 | 18 | 9 | .667 | 102 | 118 | -16 |
| July | 26 | 8 | 18 | .308 | 121 | 147 | -26 |
| August | 29 | 17 | 12 | .586 | 120 | 105 | +15 |
| Sept/Oct | 32 | 14 | 18 | .438 | 138 | 157 | -19 |
| 1-Run Games | 53 | 26 | 27 | .491 | 201 | 200 | +1 |
| Close Games (1-2-3 Runs) | 115 | 57 | 58 | .496 | 456 | 476 | -20 |
| Blowouts (7+ runs) | 7 | 6 | 1 | .857 | 48 | 46 | +2 |
| Extra Innings | 15 | 8 | 7 | .533 | 75 | 74 | +1 |
| Shutouts | 20 | 13 | 7 | .650 | 44 | 19 | +25 |
| vs LHSP | 52 | 26 | 26 | .500 | 207 | 225 | -18 |
| vs RHSP | 111 | 56 | 55 | .505 | 474 | 521 | -47 |
| vs Division | 72 | 39 | 33 | .542 | 317 | 331 | -14 |
| vs League | 145 | 71 | 74 | .490 | 613 | 661 | -48 |
| InterLeague | 18 | 11 | 7 | .611 | 68 | 85 | -17 |
