| # | Player Name | Pos | Age | B | T | Ht | Wt | Born | Place | High Level | mlbYears | Salary |
| 32 | Brian Anderson | OF | 27 | R | R | 6-2 | 205 | 3/11/1982 | Tucson,Arizona | MLB | 2005-2009 | 440,000 |
| 15 | Gordon Beckham | SS | 22 | R | R | 6-0 | 175 | 9/16/1986 | Atlanta,Georgia | MLB | 2009-2011 | min |
| 15 | Wilson Betemit | SS-3B | 27 | B | R | 6-3 | 190 | 11/2/1981 | Santo Domingo,Dominican Republic | MLB | 2001-2011 | 1,300,000 |
| 41 | Lance Broadway | P | 25 | R | R | 6-4 | 190 | 8/20/1983 | Mansfield,Texas | MLB | 2007-2009 | min |
| 56 | Mark Buehrle | P | 30 | L | L | 6-2 | 200 | 3/23/1979 | St. Charles,Missouri | MLB | 2000-2011 | 14,000,000 |
| 53 | D.J. Carrasco | P | 32 | R | R | 6-1 | 215 | 4/12/1977 | Safford,Arizona | MLB | 2003-2011 | 440,000 |
| 27 | Ramon Castro | C | 33 | R | R | 6-3 | 225 | 3/1/1976 | Veracruz,Mexico | MLB | 1999-2011 | 2,625,000 |
| 40 | Bartolo Colon | P | 34 | R | R | 6-0 | 230 | 5/24/1975 | Altamira,Dominican Republic | MLB | 1997-2011 | 1,000,000 |
| 52 | Jose Contreras | P | 37 | R | R | 6-4 | 230 | 12/6/1971 | Havana,Cuba | MLB | 2003-2011 | 10,000,000 |
| 50 | John Danks | P | 24 | L | L | 6-2 | 190 | 4/15/1985 | Austin,Texas | MLB | 2007-2011 | 520,000 |
| 26 | Octavio Dotel | P | 33 | R | R | 6-0 | 175 | 11/25/1975 | Santo Domingo,Dominican Republic | MLB | 1999-2011 | 6,000,000 |
| 23 | Jermaine Dye | RF | 35 | R | R | 6-5 | 220 | 1/28/1974 | Vacaville,California | MLB | 1996-2009 | 11,500,000 |
| 62 | Jack Egbert | P | 26 | L | R | 6-3 | 205 | 5/12/1983 | Staten Island,New York | MLB | 2009-2009 | min |
| 7 | Josh Fields | 3B | 26 | R | R | 6-2 | 210 | 12/14/1982 | Stillwater,Oklahoma | MLB | 2006-2010 | 410,000 |
| 39 | Tyler Flowers | 1B | 23 | R | R | 6-4 | 220 | 1/24/1986 | Roswell,Georgia | MLB | 2009-2011 | min |
| 34 | Gavin Floyd | P | 26 | R | R | 6-5 | 210 | 1/27/1983 | Annapolis,Maryland | MLB | 2004-2011 | 750,000 |
| 43 | Freddy Garcia | P | 32 | R | R | 6-4 | 235 | 10/6/1976 | Caracas,Venezuela | MLB | 1999-2011 | min |
| 17 | Chris Getz | SS | 25 | L | R | 6-0 | 165 | 8/30/1983 | Grosse Pointe,Michigan | MLB | 2008-2011 | 401,000 |
| 39 | Jimmy Gobble | P | 27 | L | L | 6-3 | 190 | 7/19/1981 | Bristol,Tennessee | MLB | 2003-2009 | min |
| 54 | Daniel Hudson | P | 31 | B | R | 6-2 | 185 | 10/24/1977 | Lynchburg,Virginia | MLB | 2009-2011 | min |
| 45 | Bobby Jenks | P | 28 | R | R | 6-3 | 225 | 3/14/1981 | Mission Hills,California | MLB | 2005-2011 | 5,600,000 |
| 14 | Paul Konerko | 1B | 33 | R | R | 6-3 | 211 | 3/5/1976 | Providence,Rhode Island | MLB | 1997-2011 | 12,000,000 |
| 30 | Mark Kotsay | CF-OF | 33 | L | L | 6-0 | 190 | 12/2/1975 | Whittier,California | MLB | 1997-2011 | 1,500,000 |
| 18 | Brent Lillibridge | SS | 25 | R | R | 5-11 | 185 | 9/18/1983 | Everett,Washington | MLB | 2008-2011 | 402,500 |
| 71 | Scott Linebrink | P | 32 | R | R | 6-3 | 185 | 8/4/1976 | Austin,Texas | MLB | 2000-2011 | 4,500,000 |
| 47 | Mike MacDougal | P | 32 | R | R | 6-4 | 195 | 3/5/1977 | Las Vegas,Nevada | MLB | 2001-2011 | 2,650,000 |
| 44 | Corky Miller | C | 33 | R | R | 6-1 | 220 | 3/18/1976 | Loma Linda,California | MLB | 2001-2010 | 450,000 |
| 5 | Jayson Nix | 2B | 26 | R | R | 5-11 | 180 | 8/26/1982 | Dallas,Texas | MLB | 2008-2011 | 400,000 |
| 65 | Jhonny Nunez | P | 23 | L | R | 6-3 | 185 | 11/26/1985 | San Jose de Las Matas,Dominican Republic | MLB | 2009-2009 | min |
| 7 | Jerry Owens | OF | 28 | L | L | 6-3 | 195 | 2/16/1981 | Hollywood,California | MLB | 2006-2009 | min |
| 44 | Jake Peavy | P | 28 | R | R | 6-1 | 180 | 5/31/1981 | Mobile,Alabama | MLB | 2002-2011 | 11,000,000 |
| 57 | Tony Pena | P | 27 | R | R | 6-1 | 220 | 1/9/1982 | San Pedro de Macoris,Dominican Republic | MLB | 2006-2011 | 430,000 |
| 12 | A.J. Pierzynski | C | 32 | L | R | 6-3 | 220 | 12/30/1976 | Bridgehampton,New York | MLB | 1998-2011 | 6,250,000 |
| 22 | Scott Podsednik | CF | 33 | L | L | 6-0 | 170 | 3/18/1976 | West,Texas | MLB | 2001-2010 | min |
| 49 | Aaron Poreda | P | 22 | L | L | 6-6 | 240 | 10/1/1986 | Walnut Creek,California | MLB | 2009-2009 | min |
| 20 | Carlos Quentin | OF | 26 | R | R | 6-2 | 215 | 8/28/1982 | Bellflower,California | MLB | 2006-2011 | 550,000 |
| 10 | Alexei Ramirez | CF-2B | 27 | R | R | 6-3 | 185 | 9/22/1981 | Pinar del Rio,Cuba | MLB | 2008-2011 | 1,225,000 |
| 54 | Clayton Richard | P | 25 | L | L | 6-5 | 225 | 9/12/1983 | Lafayette,Indiana | MLB | 2008-2011 | 405,000 |
| 51 | Alex Rios | RF | 28 | R | R | 6-5 | 185 | 2/18/1981 | Coffee,Alabama | MLB | 2004-2011 | 6,400,000 |
| 25 | Jim Thome | 1B-3B | 38 | L | R | 6-4 | 220 | 8/27/1970 | Peoria,Illinois | MLB | 1991-2011 | 13,000,000 |
| 37 | Matt Thornton | P | 32 | L | L | 6-6 | 220 | 9/15/1976 | Three Rivers,Michigan | MLB | 2004-2011 | 1,325,000 |
| 60 | Carlos Torres | P | 26 | R | R | 6-2 | 180 | 10/22/1982 | Santa Cruz,California | MLB | 2009-2010 | min |
| 47 | Wes Whisler | P | 26 | L | L | 6-5 | 235 | 4/7/1983 | Indianapolis,Indiana | MLB | 2009-2009 | min |
| 67 | Randy Williams | P | 33 | L | L | 6-3 | 190 | 9/18/1975 | Harlingen,Texas | MLB | 2004-2011 | min |
| 31 | Dewayne Wise | LF-RF | 31 | L | L | 6-1 | 180 | 2/24/1978 | Columbia,South Carolina | MLB | 2000-2011 | 550,000 |