| # | Player Name | Pos | Age | B | T | Ht | Wt | Born | Place | High Level | mlbYears | Salary |
| 52 | Denny Bautista | P | 25 | R | R | 6-5 | 170 | 10/23/1982 | Sanchez,Dominican Republic | MLB | 2004-2010 | 395,000 |
| 40 | Yorman Bazardo | P | 23 | R | R | 6-2 | 170 | 7/11/1984 | Maracay,Venezuela | MLB | 2005-2009 | 395,000 |
| 53 | Francis Beltran | P | 28 | R | R | 6-5 | 220 | 11/29/1979 | Santo Domingo,Dominican Republic | MLB | 2002-2008 | min |
| 38 | Jeremy Bonderman | P | 25 | R | R | 6-0 | 210 | 10/28/1982 | Pasco,Washington | MLB | 2003-2010 | 8,500,000 |
| 73 | Eddie Bonine | P | 27 | R | R | 6-5 | 205 | 6/6/1981 | Columbus,Georgia | MLB | 2008-2010 | min |
| 24 | Miguel Cabrera | LF-RF | 25 | R | R | 6-2 | 218 | 4/18/1983 | Maracay,Venezuela | MLB | 2003-2011 | 11,300,000 |
| 27 | Brent Clevlen | OF | 24 | R | R | 6-2 | 190 | 10/27/1983 | Austin,Texas | MLB | 2006-2010 | min |
| 41 | Francisco Cruceta | P | 26 | R | R | 6-2 | 173 | 7/4/1981 | Rancho Viejo,Dominican Republic | MLB | 2004-2008 | min |
| 32 | Freddy Dolsi | P | 25 | R | R | 6-0 | 160 | 1/6/1983 | San Pedro de Macoris,Dominican Republic | MLB | 2008-2009 | min |
| 48 | Kyle Farnsworth | P | 32 | R | R | 6-4 | 215 | 4/14/1976 | Wichita,Kansas | MLB | 1999-2011 | 5,916,666 |
| 49 | Casey Fossum | P | 30 | B | L | 6-1 | 160 | 1/9/1978 | Cherry Hill,New Jersey | MLB | 2001-2009 | min |
| 58 | Armando Galarraga | P | 26 | R | R | 6-3 | 170 | 1/15/1982 | Caracas,Venezuela | MLB | 2007-2011 | min |
| 34 | Freddy Garcia | P | 31 | R | R | 6-4 | 235 | 10/6/1976 | Caracas,Venezuela | MLB | 1999-2011 | min |
| 41 | Gary Glover | P | 31 | R | R | 6-5 | 205 | 12/3/1976 | Cleveland,Ohio | MLB | 1999-2008 | 1,075,000 |
| 28 | Curtis Granderson | CF | 27 | L | R | 6-1 | 180 | 3/16/1981 | Blue Island,Illinois | MLB | 2004-2011 | 1,000,000 |
| 49 | Jason Grilli | P | 31 | R | R | 6-4 | 185 | 11/11/1976 | Royal Oak,Michigan | MLB | 2000-2011 | 420,000 |
| 9 | Carlos Guillen | SS | 32 | B | R | 6-1 | 180 | 9/30/1975 | Maracay,Venezuela | MLB | 1998-2011 | 12,000,000 |
| 26 | Mike Hessman | 1B-LF | 30 | R | R | 6-5 | 215 | 3/5/1978 | Fountain Valley,California | MLB | 2003-2010 | min |
| 46 | Michael Hollimon | SS | 26 | B | R | 6-1 | 185 | 6/14/1982 | Dallas,Texas | MLB | 2008-2008 | min |
| 15 | Brandon Inge | C-3B | 31 | R | R | 5-11 | 185 | 5/19/1977 | Lynchburg,Virginia | MLB | 2001-2011 | 6,200,000 |
| 19 | Jacque Jones | LF-RF | 33 | L | L | 5-10 | 176 | 4/25/1975 | San Diego,California | MLB | 1999-2008 | 6,333,333 |
| 59 | Todd Jones | P | 40 | L | R | 6-3 | 230 | 4/24/1968 | Marietta,Georgia | MLB | 1993-2008 | 7,000,000 |
| 20 | Matt Joyce | OF | 23 | L | R | 6-2 | 185 | 8/3/1984 | Riverview,Florida | MLB | 2008-2011 | min |
| 40 | Chris Lambert | P | 25 | R | R | 6-1 | 205 | 3/8/1983 | Burlingame,California | MLB | 2008-2009 | min |
| 19 | Jeff Larish | OF-1B | 25 | L | R | 6-2 | 195 | 10/11/1982 | Iowa City,Iowa | MLB | 2008-2010 | min |
| 45 | Aquilino Lopez | P | 33 | R | R | 6-3 | 165 | 4/21/1975 | Villa Altragracia,Dominican Republic | MLB | 2003-2008 | 400,000 |
| 31 | Zach Miner | P | 26 | R | R | 6-3 | 190 | 3/12/1982 | St. Louis,Missouri | MLB | 2006-2009 | 410,000 |
| 30 | Magglio Ordonez | RF | 34 | R | R | 6-0 | 200 | 1/28/1974 | Caracas,Venezuela | MLB | 1997-2011 | 15,768,174 |
| 14 | Placido Polanco | 2B-3B | 32 | R | R | 5-10 | 168 | 10/10/1975 | Santo Domingo,Dominican Republic | MLB | 1998-2011 | 4,600,000 |
| 25 | Ryan Raburn | 2B | 27 | R | R | 6-0 | 180 | 4/17/1981 | Tampa,Florida | MLB | 2004-2011 | 396,000 |
| 50 | Clay Rapada | P | 27 | R | L | 6-5 | 180 | 3/9/1981 | Portsmouth,Virginia | MLB | 2007-2011 | min |
| 8 | Edgar Renteria | SS | 32 | R | R | 6-1 | 180 | 8/7/1975 | Barranquilla,Colombia | MLB | 1996-2011 | 10,000,000 |
| 29 | Nate Robertson | P | 30 | L | R | 6-2 | 215 | 9/3/1977 | Wichita,Kansas | MLB | 2002-2010 | 4,250,000 |
| 56 | Fernando Rodney | P | 27 | R | R | 5-11 | 170 | 3/17/1981 | Samana,Dominican Republic | MLB | 2002-2011 | 1,700,000 |
| 7 | Ivan Rodriguez | C | 36 | R | R | 5-9 | 205 | 11/30/1971 | Vega Baja,Puerto Rico | MLB | 1991-2011 | 12,379,883 |
| 37 | Kenny Rogers | P | 43 | L | L | 6-1 | 205 | 11/10/1964 | Plant City,Florida | MLB | 1989-2008 | 8,000,000 |
| 52 | Dusty Ryan | C | 23 | R | R | 6-4 | 230 | 9/2/1984 | Merced,California | MLB | 2008-2009 | min |
| 39 | Ramon Santiago | SS-2B | 28 | B | R | 5-11 | 150 | 8/31/1979 | Las Matas de Farfan,Dominican Republic | MLB | 2002-2011 | 575,000 |
| 57 | Dane Sardinha | C | 29 | R | R | 5-11 | 215 | 4/8/1979 | Honolulu,Hawaii | MLB | 2003-2011 | min |
| 44 | Bobby Seay | P | 30 | L | L | 6-2 | 221 | 6/20/1978 | Sarasota,Florida | MLB | 2001-2009 | 780,000 |
| 3 | Gary Sheffield | RF-OF | 39 | R | R | 5-11 | 205 | 11/18/1968 | Tampa,Florida | MLB | 1988-2009 | 13,326,306 |
| 33 | Marcus Thames | LF-RF | 31 | R | R | 6-2 | 205 | 3/6/1977 | Louisville,Mississippi | MLB | 2002-2011 | 1,275,000 |
| 36 | Clete Thomas | OF | 24 | L | R | 5-11 | 205 | 11/14/1983 | Jacksonville,Florida | MLB | 2008-2009 | 390,000 |
| 35 | Justin Verlander | P | 25 | R | R | 6-5 | 200 | 2/20/1983 | Manakin-Sabot,Virginia | MLB | 2005-2011 | 1,130,000 |
| 21 | Dontrelle Willis | P | 26 | L | L | 6-4 | 250 | 1/12/1982 | Oakland,California | MLB | 2003-2011 | 7,000,000 |
| 54 | Joel Zumaya | P | 23 | R | R | 6-3 | 210 | 11/9/1984 | Chula Vista,California | MLB | 2006-2010 | 420,000 |