| # | Player Name | Pos | Age | B | T | Ht | Wt | Born | Place | High Level | mlbYears | Salary |
| 40 | Yorman Bazardo | P | 22 | R | R | 6-2 | 170 | 7/11/1984 | Maracay,Venezuela | MLB | 2005-2009 | min |
| 38 | Jeremy Bonderman | P | 24 | R | R | 6-0 | 210 | 10/28/1982 | Pasco,Washington | MLB | 2003-2010 | 4,500,000 |
| 34 | Tim Byrdak | P | 33 | L | L | 5-11 | 180 | 10/31/1973 | Oak Lawn,Illinois | MLB | 1998-2011 | min |
| 41 | Jose Capellan | P | 26 | R | R | 6-3 | 170 | 1/13/1981 | Cotui,Dominican Republic | MLB | 2004-2008 | min |
| 21 | Sean Casey | 1B | 32 | L | R | 6-4 | 226 | 7/2/1974 | Willingsboro,New Jersey | MLB | 1997-2008 | 4,000,000 |
| 27 | Brent Clevlen | OF | 23 | R | R | 6-2 | 190 | 10/27/1983 | Austin,Texas | MLB | 2006-2010 | min |
| 36 | Eulogio De la cruz | P | 23 | R | R | 5-11 | 160 | 3/12/1984 | Santo Domingo,Dominican Republic | MLB | 2007-2011 | min |
| 52 | Chad Durbin | P | 29 | R | R | 6-1 | 175 | 12/3/1977 | Spring Valley,Illinois | MLB | 1999-2011 | 385,000 |
| 28,42 | Curtis Granderson | CF | 26 | L | R | 6-1 | 180 | 3/16/1981 | Blue Island,Illinois | MLB | 2004-2011 | 410,000 |
| 49 | Jason Grilli | P | 30 | R | R | 6-4 | 185 | 11/11/1976 | Royal Oak,Michigan | MLB | 2000-2011 | 395,000 |
| 9 | Carlos Guillen | SS | 31 | B | R | 6-1 | 180 | 9/30/1975 | Maracay,Venezuela | MLB | 1998-2011 | 5,000,000 |
| 24 | Mike Hessman | 1B-LF | 29 | R | R | 6-5 | 215 | 3/5/1978 | Fountain Valley,California | MLB | 2003-2010 | min |
| 20 | Omar Infante | 2B-SS | 25 | R | R | 5-9 | 150 | 12/26/1981 | Puerto La Cruz,Venezuela | MLB | 2002-2011 | 1,300,000 |
| 15 | Brandon Inge | C-3B | 30 | R | R | 5-11 | 185 | 5/19/1977 | Lynchburg,Virginia | MLB | 2001-2011 | 4,900,000 |
| 59 | Todd Jones | P | 39 | L | R | 6-3 | 230 | 4/24/1968 | Marietta,Georgia | MLB | 1993-2008 | 4,809,159 |
| 46 | Jair Jurrjens | P | 21 | R | R | 6-1 | 160 | 1/29/1986 | Curacao,Netherlands | MLB | 2007-2011 | min |
| 41 | Wil Ledezma | P | 26 | L | L | 6-3 | 152 | 1/21/1981 | Guarico,Venezuela | MLB | 2003-2011 | 415,000 |
| 45 | Aquilino Lopez | P | 32 | R | R | 6-3 | 165 | 4/21/1975 | Villa Altragracia,Dominican Republic | MLB | 2003-2008 | min |
| 46 | Mike Maroth | P | 29 | L | L | 6-0 | 180 | 8/17/1977 | Orlando,Florida | MLB | 2002-2007 | 2,950,000 |
| 4 | Cameron Maybin | OF | 20 | R | R | 6-3 | 200 | 4/4/1987 | Asheville,North Carolina | MLB | 2007-2011 | min |
| 43 | Macay McBride | P | 24 | L | L | 5-11 | 180 | 10/24/1982 | Sylvania,Georgia | MLB | 2005-2007 | 400,000 |
| 94 | Jose Mesa | P | 41 | R | R | 6-3 | 225 | 5/22/1966 | Azua,Dominican Republic | MLB | 1987-2007 | 2,500,000 |
| 48 | Andrew Miller | P | 22 | L | L | 6-6 | 175 | 5/21/1985 | Gainesville,Florida | MLB | 2006-2011 | min |
| 31 | Zach Miner | P | 25 | R | R | 6-3 | 190 | 3/12/1982 | St. Louis,Missouri | MLB | 2006-2009 | min |
| 27,42 | Craig Monroe | LF-RF | 30 | R | R | 6-1 | 195 | 2/27/1977 | Texarkana,Texas | MLB | 2001-2009 | 4,775,000 |
| 30 | Magglio Ordonez | RF | 33 | R | R | 6-0 | 200 | 1/28/1974 | Caracas,Venezuela | MLB | 1997-2011 | 13,200,000 |
| 19 | Neifi Perez | SS | 32 | B | R | 6-0 | 175 | 6/2/1975 | Villa Mella,Dominican Republic | MLB | 1996-2007 | 2,500,000 |
| 8 | Timo Perez | CF-RF | 30 | L | L | 5-9 | 167 | 4/8/1977 | Bani,Dominican Republic | MLB | 2000-2007 | min |
| 14 | Placido Polanco | 2B-3B | 31 | R | R | 5-10 | 168 | 10/10/1975 | Santo Domingo,Dominican Republic | MLB | 1998-2011 | 4,600,000 |
| 58 | Mike Rabelo | C | 27 | B | R | 6-1 | 200 | 1/17/1980 | New Port Richey,Florida | MLB | 2006-2008 | 380,000 |
| 25 | Ryan Raburn | 2B | 26 | R | R | 6-0 | 180 | 4/17/1981 | Tampa,Florida | MLB | 2004-2011 | min |
| 50 | Clay Rapada | P | 26 | R | L | 6-5 | 180 | 3/9/1981 | Portsmouth,Virginia | MLB | 2007-2011 | min |
| 29 | Nate Robertson | P | 29 | L | R | 6-2 | 215 | 9/3/1977 | Wichita,Kansas | MLB | 2002-2010 | 3,260,000 |
| 56 | Fernando Rodney | P | 26 | R | R | 5-11 | 170 | 3/17/1981 | Samana,Dominican Republic | MLB | 2002-2011 | 1,000,000 |
| 7,42 | Ivan Rodriguez | C | 35 | R | R | 5-9 | 205 | 11/30/1971 | Vega Baja,Puerto Rico | MLB | 1991-2011 | 10,567,639 |
| 37 | Kenny Rogers | P | 42 | L | L | 6-1 | 205 | 11/10/1964 | Plant City,Florida | MLB | 1989-2008 | 8,000,000 |
| 39 | Ramon Santiago | SS-2B | 27 | B | R | 5-11 | 150 | 8/31/1979 | Las Matas de Farfan,Dominican Republic | MLB | 2002-2011 | min |
| 44 | Bobby Seay | P | 29 | L | L | 6-2 | 221 | 6/20/1978 | Sarasota,Florida | MLB | 2001-2009 | 450,000 |
| 3,42 | Gary Sheffield | RF-OF | 38 | R | R | 5-11 | 205 | 11/18/1968 | Tampa,Florida | MLB | 1988-2009 | 10,916,071 |
| 53 | Jordan Tata | P | 25 | R | R | 6-6 | 220 | 9/20/1981 | Plano,Texas | MLB | 2006-2007 | min |
| 33.,42 | Marcus Thames | LF-RF | 30 | R | R | 6-2 | 205 | 3/6/1977 | Louisville,Mississippi | MLB | 2002-2011 | 432,500 |
| 32 | Virgil Vasquez | P | 25 | R | R | 6-3 | 205 | 6/7/1982 | Santa Barbara,California | MLB | 2007-2009 | min |
| 35 | Justin Verlander | P | 24 | R | R | 6-5 | 200 | 2/20/1983 | Manakin-Sabot,Virginia | MLB | 2005-2011 | 1,030,000 |
| 54 | Joel Zumaya | P | 22 | R | R | 6-3 | 210 | 11/9/1984 | Chula Vista,California | MLB | 2006-2010 | 410,000 |