| # | Player Name | Pos | Age | B | T | Ht | Wt | Born | Place | High Level | mlbYears | Salary |
| 38 | Jeremy Bonderman | P | 23 | R | R | 6-0 | 210 | 10/28/1982 | Pasco,Washington | MLB | 2003-2010 | 2,300,000 |
| 21 | Sean Casey | 1B | 31 | L | R | 6-4 | 226 | 7/2/1974 | Willingsboro,New Jersey | MLB | 1997-2008 | 8,500,000 |
| 24 | Brent Clevlen | OF | 22 | R | R | 6-2 | 190 | 10/27/1983 | Austin,Texas | MLB | 2006-2010 | 327,000 |
| 43 | Roman Colon | P | 26 | R | R | 6-3 | 170 | 8/13/1979 | Monte Cristi,Dominican Republic | MLB | 2004-2010 | 327,000 |
| 52 | Chad Durbin | P | 28 | R | R | 6-1 | 175 | 12/3/1977 | Spring Valley,Illinois | MLB | 1999-2011 | 327,000 |
| 45 | Alexis Gomez | RF-LF | 25 | L | L | 6-2 | 160 | 8/6/1980 | Loma de Cabrera,Dominican Republic | MLB | 2002-2006 | 327,000 |
| 28 | Curtis Granderson | CF | 25 | L | R | 6-1 | 180 | 3/16/1981 | Blue Island,Illinois | MLB | 2004-2011 | 335,000 |
| 49 | Jason Grilli | P | 29 | R | R | 6-4 | 185 | 11/11/1976 | Royal Oak,Michigan | MLB | 2000-2011 | 350,000 |
| 9 | Carlos Guillen | SS | 30 | B | R | 6-1 | 180 | 9/30/1975 | Maracay,Venezuela | MLB | 1998-2011 | 5,000,000 |
| 36 | Jack Hannahan | 3B | 26 | L | R | 6-2 | 200 | 3/4/1980 | St. Paul,Minnesota | MLB | 2006-2011 | 327,000 |
| 19 | Kevin Hooper | 2B | 29 | R | R | 5-9 | 155 | 12/7/1976 | Lawrence,Kansas | MLB | 2005-2006 | 327,000 |
| 20 | Omar Infante | 2B-SS | 24 | R | R | 5-9 | 150 | 12/26/1981 | Puerto La Cruz,Venezuela | MLB | 2002-2011 | 385,000 |
| 15 | Brandon Inge | C-3B | 29 | R | R | 5-11 | 185 | 5/19/1977 | Lynchburg,Virginia | MLB | 2001-2011 | 3,000,000 |
| 59 | Todd Jones | P | 38 | L | R | 6-3 | 230 | 4/24/1968 | Marietta,Georgia | MLB | 1993-2008 | 5,792,956 |
| 41 | Wil Ledezma | P | 25 | L | L | 6-3 | 152 | 1/21/1981 | Guarico,Venezuela | MLB | 2003-2011 | 327,000 |
| 36 | Colby Lewis | P | 26 | R | R | 6-4 | 215 | 8/2/1979 | Bakersfield,California | MLB | 2002-2011 | 327,000 |
| 46 | Mike Maroth | P | 28 | L | L | 6-0 | 180 | 8/17/1977 | Orlando,Florida | MLB | 2002-2007 | 2,300,000 |
| 50 | Andrew Miller | P | 21 | L | L | 6-6 | 175 | 5/21/1985 | Gainesville,Florida | MLB | 2006-2011 | 327,000 |
| 31 | Zach Miner | P | 24 | R | R | 6-3 | 190 | 3/12/1982 | St. Louis,Missouri | MLB | 2006-2009 | 327,000 |
| 27 | Craig Monroe | LF-RF | 29 | R | R | 6-1 | 195 | 2/27/1977 | Texarkana,Texas | MLB | 2001-2009 | 2,800,000 |
| 30 | Magglio Ordonez | RF | 32 | R | R | 6-0 | 200 | 1/28/1974 | Caracas,Venezuela | MLB | 1997-2011 | 16,200,000 |
| 8 | Neifi Perez | SS | 31 | B | R | 6-0 | 175 | 6/2/1975 | Villa Mella,Dominican Republic | MLB | 1996-2007 | 2,500,000 |
| 14 | Placido Polanco | 2B-3B | 30 | R | R | 5-10 | 168 | 10/10/1975 | Santo Domingo,Dominican Republic | MLB | 1998-2011 | 4,600,000 |
| 58 | Mike Rabelo | C | 26 | B | R | 6-1 | 200 | 1/17/1980 | New Port Richey,Florida | MLB | 2006-2008 | 327,000 |
| 29 | Nate Robertson | P | 28 | L | R | 6-2 | 215 | 9/3/1977 | Wichita,Kansas | MLB | 2002-2010 | 402,500 |
| 56 | Fernando Rodney | P | 25 | R | R | 5-11 | 170 | 3/17/1981 | Samana,Dominican Republic | MLB | 2002-2011 | 385,000 |
| 7 | Ivan Rodriguez | C | 34 | R | R | 5-9 | 205 | 11/30/1971 | Vega Baja,Puerto Rico | MLB | 1991-2011 | 10,616,410 |
| 37 | Kenny Rogers | P | 41 | L | L | 6-1 | 205 | 11/10/1964 | Plant City,Florida | MLB | 1989-2008 | 8,000,000 |
| 39 | Ramon Santiago | SS-2B | 26 | B | R | 5-11 | 150 | 8/31/1979 | Las Matas de Farfan,Dominican Republic | MLB | 2002-2011 | 375,000 |
| 44 | Bobby Seay | P | 28 | L | L | 6-2 | 221 | 6/20/1978 | Sarasota,Florida | MLB | 2001-2009 | 375,000 |
| 26 | Chris Shelton | 1B-C | 26 | R | R | 6-0 | 200 | 6/26/1980 | Salt Lake City,Utah | MLB | 2004-2009 | 365,000 |
| 48 | Chris Spurling | P | 29 | R | R | 6-5 | 228 | 6/28/1977 | Dayton,Ohio | MLB | 2003-2007 | 725,000 |
| 25 | Matt Stairs | RF-1B | 38 | L | R | 5-9 | 217 | 2/27/1968 | Saint John,New Brunswick | MLB | 1992-2011 | 1,350,000 |
| 53 | Jordan Tata | P | 24 | R | R | 6-6 | 220 | 9/20/1981 | Plano,Texas | MLB | 2006-2007 | 327,000 |
| 33 | Marcus Thames | LF-RF | 29 | R | R | 6-2 | 205 | 3/6/1977 | Louisville,Mississippi | MLB | 2002-2011 | 342,000 |
| 35 | Justin Verlander | P | 23 | R | R | 6-5 | 200 | 2/20/1983 | Manakin-Sabot,Virginia | MLB | 2005-2011 | 980,000 |
| 32 | Jamie Walker | P | 34 | L | L | 6-2 | 190 | 7/1/1971 | McMinnville,Tennessee | MLB | 1997-2009 | 1,250,000 |
| 13 | Vance Wilson | C | 33 | R | R | 5-11 | 190 | 3/17/1973 | Mesa,Arizona | MLB | 2000-2006 | 750,000 |
| 25 | Dmitri Young | LF-1B | 32 | B | R | 6-2 | 235 | 10/11/1973 | Vicksburg,Mississippi | MLB | 1996-2008 | 8,000,000 |
| 54 | Joel Zumaya | P | 21 | R | R | 6-3 | 210 | 11/9/1984 | Chula Vista,California | MLB | 2006-2010 | 327,000 |