| 2010-04-08 | CLE | 25.017 | W 5-3 | @ CHA | 1 | 79 | - | ST | 5.0 | 4 | 1 | 1 | 0 | 2 | 5 | 92 | 34 | 58 | 63% | 0-0 | 1.80 | 1.20 |
| 2010-04-14 | CLE | 25.023 | W 2-6 | vs TEX | 2 | 80 | L | ST | 6.0 | 9 | 4 | 2 | 1 | 0 | 9 | 103 | 37 | 66 | 64% | 0-1 | 2.45 | 1.36 |
| 2010-04-20 | CLE | 25.029 | L 1-5 | @ MIN | 3 | 81 | L | ST | 4.0 | 5 | 5 | 2 | 0 | 5 | 6 | 97 | 42 | 55 | 57% | 0-2 | 3.00 | 1.67 |
| 2010-04-25 | CLE | 25.034 | L 0-11 | @ OAK | 4 | 82 | L | ST | 4.0 | 8 | 7 | 7 | 1 | 4 | 4 | 96 | 43 | 53 | 55% | 0-3 | 5.68 | 1.95 |
| 2010-05-01 | CLE | 25.040 | L 5-4 | vs MIN | 5 | 83 | - | ST | 7.2 | 10 | 4 | 4 | 2 | 1 | 7 | 116 | 35 | 81 | 70% | 0-3 | 5.33 | 1.78 |
| 2010-05-08 | CLE | 25.047 | W 4-6 | vs DET | 6 | 84 | - | ST | 6.0 | 5 | 3 | 3 | 0 | 3 | 8 | 112 | 43 | 69 | 62% | 0-3 | 5.18 | 1.70 |
| 2010-05-14 | CLE | 25.053 | L 1-8 | @ BAL | 7 | 85 | L | ST | 5.1 | 8 | 6 | 6 | 0 | 5 | 4 | 111 | 50 | 61 | 55% | 0-4 | 5.92 | 1.82 |
| 2010-05-19 | CLE | 25.058 | W 4-8 | vs KCA | 8 | 86 | - | ST | 5.0 | 5 | 2 | 2 | 0 | 4 | 3 | 106 | 42 | 64 | 60% | 0-4 | 5.65 | 1.81 |
| 2010-05-24 | CLE | 25.063 | W 2-7 | vs CHA | 9 | 87 | L | ST | 4.0 | 9 | 5 | 5 | 0 | 2 | 0 | 95 | 38 | 57 | 60% | 0-5 | 6.13 | 1.89 |
| 2010-05-30 | CLE | 25.069 | L 3-7 | @ NYA | 10 | 88 | - | ST | 6.2 | 7 | 3 | 3 | 0 | 1 | 8 | 106 | 38 | 68 | 64% | 0-5 | 5.83 | 1.80 |
| 2010-06-04 | CLE | 25.074 | W 10-1 | @ CHA | 11 | 89 | W | ST | 5.2 | 5 | 1 | 1 | 1 | 6 | 1 | 114 | 50 | 64 | 56% | 1-5 | 5.49 | 1.83 |
| 2010-06-09 | CLE | 25.079 | L 11-0 | vs BOS | 12 | 90 | W | ST | 9.0 | 2 | 0 | 0 | 0 | 2 | 6 | 109 | 35 | 74 | 68% | 2-5 | 4.76 | 1.65 |
| 2010-06-15 | CLE | 25.085 | W 6-7 | vs NYN | 13 | 91 | L | ST | 7.0 | 10 | 7 | 6 | 1 | 2 | 2 | 100 | 37 | 63 | 63% | 2-6 | 5.04 | 1.65 |
| 2010-06-20 | CLE | 25.090 | L 3-5 | @ PIT | 14 | 92 | - | ST | 6.0 | 5 | 2 | 2 | 0 | 1 | 7 | 109 | 43 | 66 | 61% | 2-6 | 4.89 | 1.60 |
| 2010-06-26 | CLE | 25.096 | L 4-6 | @ CIN | 15 | 93 | L | ST | 5.0 | 6 | 6 | 6 | 0 | 4 | 2 | 96 | 38 | 58 | 60% | 2-7 | 5.23 | 1.63 |
| 2010-07-01 | CLE | 25.101 | L 6-1 | vs TOR | 16 | 94 | W | ST | 8.1 | 8 | 1 | 1 | 0 | 0 | 5 | 109 | 37 | 72 | 66% | 3-7 | 4.83 | 1.56 |
| 2010-07-06 | CLE | 25.106 | L 1-12 | @ TEX | 17 | 95 | L | ST | 5.1 | 9 | 7 | 7 | 1 | 3 | 3 | 96 | 38 | 58 | 60% | 3-8 | 5.22 | 1.60 |
| 2010-07-11 | CLE | 25.111 | L 5-6 | @ TBA | 18 | 96 | - | ST | 5.0 | 8 | 5 | 4 | 1 | 3 | 2 | 103 | 43 | 60 | 58% | 3-8 | 5.31 | 1.63 |
| 2010-07-20 | CLE | 25.120 | W 4-3 | @ MIN | 19 | 97 | - | ST | 6.1 | 7 | 3 | 3 | 0 | 1 | 7 | 109 | 38 | 71 | 65% | 3-8 | 5.27 | 1.61 |
| 2010-07-25 | CLE | 25.125 | W 2-4 | vs TBA | 20 | 98 | L | ST | 6.2 | 5 | 4 | 3 | 1 | 2 | 5 | 111 | 43 | 68 | 61% | 3-9 | 5.19 | 1.58 |
| 2010-07-30 | CLE | 25.130 | L 1-8 | @ TOR | 21 | 99 | L | ST | 5.1 | 13 | 8 | 8 | 2 | 2 | 3 | 116 | 40 | 76 | 66% | 3-10 | 5.56 | 1.63 |
| 2010-08-04 | CLE | 25.135 | W 9-1 | @ BOS | 22 | 100 | W | ST | 5.0 | 4 | 1 | 1 | 1 | 4 | 3 | 92 | 44 | 48 | 52% | 4-10 | 5.41 | 1.63 |
| 2010-08-10 | CLE | 25.141 | W 8-14 | vs BAL | 23 | 101 | L | ST | 5.0 | 6 | 7 | 4 | 1 | 3 | 3 | 88 | 32 | 56 | 64% | 4-11 | 5.48 | 1.64 |
| 2010-08-15 | CLE | 25.146 | L 9-1 | vs SEA | 24 | 102 | - | ST | 6.0 | 1 | 0 | 0 | 0 | 6 | 3 | 100 | 51 | 49 | 49% | 4-11 | 5.24 | 1.62 |
| 2010-08-20 | CLE | 25.151 | L 0-6 | @ DET | 25 | 103 | L | ST | 6.0 | 11 | 5 | 5 | 0 | 1 | 5 | 115 | 39 | 76 | 66% | 4-12 | 5.34 | 1.63 |
| 2010-08-26 | CLE | 25.157 | L 3-2 | vs OAK | 26 | 104 | W | ST | 6.0 | 5 | 2 | 2 | 0 | 2 | 3 | 89 | 35 | 54 | 61% | 5-12 | 5.25 | 1.62 |
| 2010-08-31 | CLE | 25.162 | W 3-4 | vs CHA | 27 | 105 | - | ST | 7.2 | 4 | 1 | 1 | 0 | 2 | 7 | 101 | 37 | 64 | 63% | 5-12 | 5.04 | 1.57 |
| 2010-09-07 | CLE | 25.169 | W 6-1 | @ ANA | 28 | 106 | W | ST | 7.0 | 6 | 1 | 1 | 1 | 2 | 5 | 101 | 36 | 65 | 64% | 6-12 | 4.88 | 1.55 |
| 2010-09-12 | CLE | 25.174 | W 2-6 | vs MIN | 29 | 107 | - | Rel | 7.0 | 5 | 3 | 1 | 0 | 0 | 6 | 97 | 34 | 63 | 65% | 6-12 | 4.73 | 1.52 |
| 2010-09-18 | CLE | 25.180 | W 6-4 | @ KCA | 30 | 108 | - | ST | 3.1 | 3 | 0 | 0 | 0 | 0 | 4 | 52 | 19 | 33 | 63% | 6-12 | 4.65 | 1.51 |
| 2010-09-21 | CLE | 25.183 | L 4-6 | @ MIN | 31 | 109 | L | Rel | 0.2 | 3 | 3 | 3 | 0 | 0 | 0 | 19 | 6 | 13 | 68% | 6-13 | 4.78 | 1.52 |
| 2010-09-25 | CLE | 25.187 | L 7-1 | vs KCA | 32 | 110 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 13 | 5 | 8 | 62% | 6-13 | 4.75 | 1.51 |
| 2010-09-29 | CLE | 25.191 | L 4-3 | vs DET | 33 | 111 | - | Rel | 1.0 | 0 | 0 | 0 | 0 | 0 | 2 | 12 | 2 | 10 | 83% | 6-13 | 4.73 | 1.50 |
| 2010-10-03 | CLE | 25.195 | L 5-6 | @ CHA | 34 | 112 | - | Rel | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 13 | 5 | 8 | 62% | 6-13 | 4.70 | 1.50 |