| 2006-04-06 | COL | 25.088 | W 5-12 | vs ARI | 1 | 41 | L | ST | 4.1 | 5 | 5 | 5 | 1 | 6 | 3 | 93 | 45 | 48 | 52% | 0-1 | 11.25 | 2.75 |
| 2006-04-12 | COL | 25.094 | L 4-5 | @ ARI | 2 | 42 | - | ST | 5.2 | 5 | 3 | 3 | 2 | 2 | 6 | 99 | 37 | 62 | 63% | 0-1 | 7.20 | 1.80 |
| 2006-04-17 | COL | 25.099 | W 2-5 | vs SDN | 3 | 43 | L | ST | 6.0 | 6 | 5 | 4 | 1 | 3 | 7 | 108 | 48 | 60 | 56% | 0-2 | 6.75 | 1.69 |
| 2006-04-23 | COL | 25.105 | L 3-2 | vs SFN | 4 | 44 | - | ST | 6.2 | 4 | 1 | 1 | 0 | 1 | 4 | 96 | 37 | 59 | 61% | 0-2 | 5.09 | 1.39 |
| 2006-04-28 | COL | 25.110 | W 3-2 | @ FLO | 5 | 45 | - | ST | 5.1 | 3 | 1 | 1 | 0 | 6 | 6 | 107 | 50 | 57 | 53% | 0-2 | 4.50 | 1.46 |
| 2006-05-03 | COL | 25.115 | L 3-0 | vs CIN | 6 | 46 | W | ST | 7.0 | 4 | 0 | 0 | 0 | 1 | 5 | 93 | 36 | 57 | 61% | 1-2 | 3.60 | 1.31 |
| 2006-05-08 | COL | 25.120 | W 6-2 | @ SLN | 7 | 47 | W | ST | 7.2 | 6 | 1 | 1 | 0 | 3 | 1 | 109 | 46 | 63 | 58% | 2-2 | 3.14 | 1.28 |
| 2006-05-14 | COL | 25.126 | L 0-3 | @ HOU | 8 | 48 | L | ST | 7.0 | 6 | 3 | 3 | 2 | 2 | 5 | 117 | 46 | 71 | 61% | 2-3 | 3.24 | 1.26 |
| 2006-05-20 | COL | 25.132 | L 5-1 | vs TOR | 9 | 49 | W | ST | 6.0 | 4 | 1 | 1 | 0 | 3 | 2 | 85 | 33 | 52 | 61% | 3-3 | 3.05 | 1.25 |
| 2006-05-26 | COL | 25.138 | L 0-9 | @ SFN | 10 | 50 | L | ST | 5.0 | 7 | 7 | 7 | 0 | 4 | 2 | 94 | 43 | 51 | 54% | 3-4 | 3.84 | 1.33 |
| 2006-05-31 | COL | 25.143 | L 2-3 | @ SDN | 11 | 51 | L | ST | 5.2 | 4 | 3 | 2 | 0 | 2 | 7 | 93 | 36 | 57 | 61% | 3-5 | 3.82 | 1.32 |
| 2006-06-06 | COL | 25.149 | L 5-4 | vs PIT | 12 | 52 | W | ST | 6.0 | 3 | 3 | 3 | 2 | 1 | 5 | 74 | 24 | 50 | 68% | 4-5 | 3.88 | 1.26 |
| 2006-06-12 | COL | 25.155 | W 4-3 | @ WAS | 13 | 53 | W | ST | 6.2 | 4 | 2 | 2 | 0 | 3 | 3 | 99 | 40 | 59 | 60% | 5-5 | 3.76 | 1.24 |
| 2006-06-17 | COL | 25.160 | L 5-6 | @ SLN | 14 | 54 | L | ST | 6.0 | 6 | 6 | 6 | 2 | 1 | 2 | 102 | 37 | 65 | 64% | 5-6 | 4.13 | 1.24 |
| 2006-06-23 | COL | 25.166 | W 6-8 | vs TEX | 15 | 55 | L | ST | 5.2 | 8 | 5 | 5 | 0 | 2 | 2 | 93 | 35 | 58 | 62% | 5-7 | 4.35 | 1.26 |
| 2006-06-28 | COL | 25.171 | W 6-2 | @ ANA | 16 | 56 | - | ST | 6.2 | 9 | 2 | 2 | 0 | 2 | 4 | 115 | 44 | 71 | 62% | 5-7 | 4.27 | 1.30 |
| 2006-07-04 | COL | 25.177 | L 6-1 | vs SFN | 17 | 57 | W | ST | 5.0 | 1 | 0 | 0 | 0 | 1 | 1 | 70 | 24 | 46 | 66% | 6-7 | 4.06 | 1.25 |
| 2006-07-13 | COL | 25.186 | L 7-9 | @ CIN | 18 | 58 | L | ST | 6.0 | 8 | 4 | 4 | 0 | 2 | 5 | 116 | 38 | 78 | 67% | 6-8 | 4.17 | 1.28 |
| 2006-07-18 | COL | 25.191 | W 13-4 | @ PIT | 19 | 59 | W | ST | 7.0 | 8 | 2 | 1 | 0 | 1 | 6 | 111 | 39 | 72 | 65% | 7-8 | 3.99 | 1.28 |
| 2006-07-24 | COL | 25.197 | L 7-0 | vs SLN | 20 | 60 | W | ST | 9.0 | 2 | 0 | 0 | 0 | 0 | 8 | 129 | 41 | 88 | 68% | 8-8 | 3.70 | 1.20 |
| 2006-07-29 | COL | 25.202 | W 2-4 | vs SDN | 21 | 61 | L | ST | 7.0 | 5 | 4 | 2 | 2 | 4 | 2 | 108 | 46 | 62 | 57% | 8-9 | 3.64 | 1.21 |
| 2006-08-04 | COL | 25.208 | W 5-2 | @ SFN | 22 | 62 | W | ST | 8.0 | 6 | 2 | 2 | 2 | 0 | 2 | 92 | 33 | 59 | 64% | 9-9 | 3.56 | 1.18 |
| 2006-08-09 | COL | 25.213 | W 3-1 | @ LAN | 23 | 63 | - | ST | 7.1 | 6 | 1 | 1 | 0 | 4 | 2 | 120 | 53 | 67 | 56% | 9-9 | 3.43 | 1.18 |
| 2006-08-14 | COL | 25.218 | L 4-3 | vs ARI | 24 | 64 | - | ST | 7.1 | 5 | 2 | 2 | 0 | 1 | 4 | 97 | 38 | 59 | 61% | 9-9 | 3.39 | 1.17 |
| 2006-08-19 | COL | 25.223 | L 4-7 | @ NYN | 25 | 65 | L | ST | 5.2 | 5 | 6 | 2 | 0 | 3 | 2 | 106 | 39 | 67 | 63% | 9-10 | 3.38 | 1.18 |
| 2006-08-25 | COL | 25.229 | L 13-5 | vs SDN | 26 | 66 | W | ST | 6.0 | 8 | 5 | 5 | 0 | 3 | 3 | 93 | 39 | 54 | 58% | 10-10 | 3.52 | 1.20 |
| 2006-08-31 | COL | 25.235 | L 8-4 | vs NYN | 27 | 67 | W | ST | 5.0 | 10 | 4 | 4 | 1 | 2 | 3 | 103 | 44 | 59 | 57% | 11-10 | 3.63 | 1.23 |
| 2006-09-05 | COL | 25.240 | L 4-5 | @ SDN | 28 | 68 | L | ST | 5.0 | 10 | 5 | 5 | 1 | 2 | 3 | 95 | 38 | 57 | 60% | 11-11 | 3.78 | 1.27 |
| 2006-09-10 | COL | 25.245 | L 13-9 | vs WAS | 29 | 69 | - | ST | 4.0 | 10 | 6 | 6 | 1 | 0 | 2 | 80 | 28 | 52 | 65% | 11-11 | 4.00 | 1.29 |
| 2006-09-17 | COL | 25.252 | W 6-1 | @ ARI | 30 | 70 | W | ST | 8.0 | 3 | 1 | 1 | 0 | 0 | 5 | 97 | 32 | 65 | 67% | 12-11 | 3.88 | 1.26 |
| 2006-09-23 | COL | 25.258 | L 10-9 | vs ATL | 31 | 71 | W | ST | 5.0 | 9 | 5 | 5 | 1 | 3 | 2 | 93 | 39 | 54 | 58% | 13-11 | 4.01 | 1.28 |
| 2006-09-30 | COL | 25.265 | W 11-9 | @ CHN | 32 | 72 | - | ST | 6.1 | 7 | 6 | 6 | 0 | 1 | 3 | 96 | 31 | 65 | 68% | 13-11 | 4.16 | 1.29 |