| Rnd | Ovl | Phase | Player Name | $$ | Pos | Age | Born | Ht | Wt | B | T | High Level | MLB Years | Drafted From |
| 1 | 25 | June-Reg | Matt Garza | $$ | rhp | 21 | 11/11/1983 | 6-4 | 205 | R | R | MLB | 2006-2008 | Fresno State University |
| 1 | 39 | June-Reg | Henry Sanchez | $$ | 1b | 18 | 11/29/1986 | 6-3 | 235 | R | R | A | | Mission Bay High School (San Diego,CA) |
| 2 | 54 | June-Reg | Paul Kelly | $$ | ss | 18 | 10/19/1986 | 6-0 | 185 | R | R | A | | Flower Mound High School (Flower Mound,TX) |
| 2 | 73 | June-Reg | Kevin Slowey | $$ | rhp | 21 | 5/4/1984 | 6-3 | 190 | R | R | MLB | 2007-2008 | Winthrop University |
| 2 | 80 | June-Reg | Andrew Thompson | $$ | ss | 18 | 11/7/1986 | 6-1 | 160 | L | R | A+ | | Jupiter Community High School (Jupiter,FL) |
| 3 | 84 | June-Reg | Brian Duensing | $$ | LHP | 22 | 2/22/1983 | 5-11 | 195 | L | L | AAA | | University of Nebraska |
| 3 | 105 | June-Reg | Ryan Mullins | | RHP | 21 | 11/13/1983 | 6-6 | 180 | L | L | AAA | | Vanderbilt University |
| 4 | 135 | June-Reg | Caleb Moore | | c | 22 | 5/17/1983 | 5-11 | 205 | R | R | A+ | | East Tennessee State University |
| 5 | 165 | June-Reg | Steven Tolleson | | ss | 21 | 11/1/1983 | 5-10 | 180 | R | R | AA | | University of South Carolina |
| 6 | 195 | June-Reg | J.W. Wilson | | of | 18 | 8/19/1986 | 6-2 | 195 | R | R | Rookie | | Midland High School (Midland,TX) |
| 7 | 225 | June-Reg | Gregory Yersich | | C | 18 | 10/7/1986 | 6-0 | 205 | R | R | A | | Andrean High School (Merrillville,IN) |
| 8 | 255 | June-Reg | Daniel Powers | | RHP | 22 | 7/24/1982 | 6-1 | 195 | R | R | AA | | Central Missouri State University |
| 9 | 285 | June-Reg | Erik Lis | | 1b | 21 | 3/8/1984 | 6-1 | 220 | L | L | AA | | University of Evansville |
| 10 | 315 | June-Reg | Matt Betsill | | 3B | 20 | 8/16/1984 | 6-5 | 190 | B | R | A+ | | Furman University |
| 11 | 345 | June-Reg | Brian Kirwan | | rhp | 18 | 6/9/1987 | 6-4 | 205 | R | R | A | | Santa Fe Christian High School (Solana Beach,CA) |
| 12 | 375 | June-Reg | Alex Burnett | | rhp | 17 | 7/26/1987 | 6-0 | 190 | R | R | A+ | | Ocean View High School (Huntington Beach,CA) |
| 13 | 405 | June-Reg | Michael Allen | | rhp | 18 | 5/27/1987 | 6-3 | 220 | R | R | A+ | | Arlington Country Day School High School (Jacksonville,FL) |
| 14 | 435 | June-Reg | David Duncan | | LHP | 19 | 6/1/1986 | 6-9 | 230 | L | L | College | | New Richmond High School (New Richmond,OH) |
| 15 | 465 | June-Reg | Michael Hacker | | LHP | 19 | 11/6/1985 | 5-9 | 175 | L | L | - | | Cosumnes River College |
| 16 | 495 | June-Reg | Yonder Alonso | | c | 18 | 4/8/1987 | 6-2 | 215 | L | R | College | | Coral Gables High School (Coral Gables,FL) |
| 17 | 525 | June-Reg | Robert Lara | | C | 18 | 11/25/1986 | 6-2 | 205 | R | R | College | | Nova High School (Davie,FL) |
| 18 | 555** | June-Reg | Matt Morgal | | rhp | 18 | 9/18/1986 | 6-5 | 220 | R | R | College | | Edmond Santa Fe High School (Edmond,OK) |
| 19 | 585 | June-Reg | Sean Richardson | | c | 21 | 10/2/1983 | 6-1 | 185 | R | R | Rookie | | University of Kansas |
| 20 | 615** | June-Reg | Eric Santiago | | ss | 17 | 7/10/1987 | 6-0 | 185 | R | R | Rookie | | Natividad Rodriguez Gonza (Arroyo,PR) |
| 21 | 645 | June-Reg | Chris Kelley | | RHP | 19 | 8/8/1985 | 6-1 | 200 | R | R | College | | San Jacinto College-North |
| 22 | 675 | June-Reg | Curtis Leavitt | | lhp | 18 | 1/10/1987 | 6-4 | 200 | R | R | Rookie | | Vasquez High School (Acton,CA) |
| 23 | 705** | June-Reg | Kenneth Herndon | | rhp | 19 | 9/4/1985 | 6-5 | 200 | R | R | A+ | | Gulf Coast Community College |
| 24 | 735 | June-Reg | Gustavo Duran | | RHP | 19 | 4/16/1986 | 6-3 | 205 | R | R | - | | |
| 25 | 765 | June-Reg | Aaron Lovett | | rhp | 19 | 6/26/1986 | 6-5 | 195 | R | R | College | | Kaskaskia College |
| 26 | 795** | June-Reg | Michael Mopas | | LHP | 17 | 12/23/1987 | 6-1 | 170 | L | L | Rookie | | Iolani High School (Honolulu,HI) |
| 27 | 825** | June-Reg | Evan Frederickson | | lhp | 18 | 9/23/1986 | 6-6 | 238 | L | L | College | | Oakton High School (Vienna,VA) |
| 28 | 855 | June-Reg | Josh Brink | | rhp | 18 | 2/7/1987 | 6-5 | 230 | R | R | - | | Menonite Educational Institute High School (Abbottsford,BC) |
| 29 | 885 | June-Reg | Steve Hernandez | | RHP | 17 | 7/23/1987 | 6-2 | 220 | L | R | - | | Redwood High School (Visalia,CA) |
| 30 | 915 | June-Reg | Kiko Vazquez | | 1b | 18 | 9/10/1986 | 6-3 | 225 | R | R | College | | Sebring High School (Sebring,FL) |
| 31 | 945 | June-Reg | Kyle Carr | | lhp | 18 | 11/11/1986 | 6-5 | 200 | R | L | College | | Linton High School (Linton,ND) |
| 32 | 975 | June-Reg | David Bromberg | | RHP | 17 | 9/14/1987 | 6-5 | 225 | L | R | A | | Palisades High School (Pacific Palisades,CA) |
| 33 | 1005** | June-Reg | Brandon Trodick | | of | 18 | 5/4/1987 | 6-2 | 180 | R | R | - | | Cimarron Memorial High School (Las Vegas,NV) |
| 34 | 1035 | June-Reg | Danny Cox | | SS | 18 | 7/10/1986 | 6-1 | 180 | L | R | A | | W.F. West High School (Chehalis,WA) |
| 35 | 1065 | June-Reg | Lukas Thomason | | rhp | 18 | 9/19/1986 | 6-5 | 210 | R | R | - | | Brook Hill High School (Jacksonville,TX) |
| 36 | 1095 | June-Reg | Rene Tosoni | | of | 18 | 7/2/1986 | 6-0 | 205 | L | R | A+ | | Chipola College |
| 37 | 1125 | June-Reg | James Leigh | | LHP | | | | | | | College | | Texarkana College |
| 38 | 1155 | June-Reg | Carlos Rodriguez | | c | 18 | 2/19/1987 | 6-0 | 174 | R | R | College | | Puerto Rico Baseball Academy High School (Gurabo,PR) |
| 39 | 1184 | June-Reg | Charles Duffey | | rhp | 18 | 2/23/1987 | 6-3 | 195 | R | R | - | | Westminster High School (Westminster,CA) |
| 40 | 1213 | June-Reg | Charles Leesman | | LHP | 18 | 3/10/1987 | 6-4 | 210 | L | L | College | | Elder High School (Cincinnati,OH) |
| 41 | 1242 | June-Reg | Toby Gardenhire | | ss | 22 | 9/11/1982 | 6-0 | 170 | R | R | AA | | University of Illinois |
| 42 | 1271 | June-Reg | Jacob Cox | | C | 18 | 1/3/1987 | 5-10 | 180 | R | R | - | | Lakeland High School (Lakeland,FL) |
| 43 | 1300 | June-Reg | Justin Parker | | rhp | 18 | 3/14/1987 | 6-1 | 190 | R | R | College | | Fort Wayne High School (Fort Wayne,IN) |
| 44 | 1329 | June-Reg | Jose Cordero | | rhp | 21 | 8/7/1983 | 6-2 | 230 | R | R | A | | |
| 45 | 1358 | June-Reg | Michael Kinsel | | SS | 18 | 3/18/1987 | 6-0 | 0 | R | R | - | | Cretin-Derham Hall High School (St. Paul,MN) |
| 46 | 1387 | June-Reg | Denver Wynn | | RHP | 18 | 6/30/1987 | 6-3 | 175 | R | R | - | | |
| 47 | 1415** | June-Reg | Mike Ballard | | lhp | | | 6-2 | 185 | L | L | AA | | University of Virginia |
| 48 | 1443 | June-Reg | Juan Rodriguez | | c | 18 | 5/24/1987 | 6-2 | 200 | R | R | - | | Bayamon Military Academy (Bayamon,PR) |
| 49 | 1470 | June-Reg | Dane Ponciano | | c | | | | | | | - | | Community College of Southern Nevada |
| 50 | 1497 | June-Reg | Justin Otto | | RHP | | | | | | | - | | Cowley County Community College |
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