| 1 | 8 | June-Reg | Scott Moore | | SS | 18 | 11/17/1983 | 6-2 | 180 | L | R | MLB | 2006-2008 | Cypress High School (Cypress,CA) |
| 2 | 49 | June-Reg | Brent Clevlen | | OF | 18 | 10/27/1983 | 6-2 | 190 | R | R | MLB | 2006-2008 | Westwood High School (Austin,TX) |
| 3 | 87 | June-Reg | Matt Pender | | P | 21 | 6/11/1981 | 6-5 | 210 | R | R | A+ | | Kennesaw State University |
| 4 | 110 | June-Reg | Robbie Sovie | | OF | 18 | 11/24/1983 | 6-0 | 200 | R | R | A- | | Steubenville High School (Steubenville,OH) |
| 5 | 140 | June-Reg | Bo Flowers | | OF | 18 | 11/12/1983 | 6-0 | 180 | R | R | A | | Walther Lutheran High School (Melrose Park,IL) |
| 6 | 170 | June-Reg | Chris Maples | | 3B | 22 | 10/31/1979 | 5-10 | 180 | R | R | AAA | | University of North Carolina |
| 9 | 260 | June-Reg | Marcos Hernandez | | P | 18 | 5/25/1984 | 6-4 | 200 | L | L | Rookie | | Juan Ponce De Leon High School (Sabana Hoyos,PR) |
| 11 | 320 | June-Reg | Joel Zumaya | | P | 17 | 11/9/1984 | 6-3 | 210 | R | R | MLB | 2006-2007 | Bonita Vista High School (Chula Vista,CA) |
| 12 | 350 | June-Reg | Corey Hamman | | P | 22 | 4/12/1980 | 6-2 | 190 | L | L | AAA | | Montclair State University |
| 14 | 410 | June-Reg | Jason Graham | | P | 22 | 9/24/1979 | 6-3 | 190 | R | R | A | | University of Central Florida |
| 15 | 440 | June-Reg | Jesse Carlson | | P | 21 | 12/31/1980 | 6-1 | 160 | L | L | MLB | 2008-2008 | University of Connecticut |
| 16 | 470 | June-Reg | Michael Smith | | P | 20 | 7/8/1981 | 6-5 | 205 | L | L | Rookie | | Valdosta State University |
| 17 | 500 | June-Reg | Rob Watson | | IF | 22 | 12/31/1979 | 5-10 | 180 | R | R | A+ | | Oklahoma State University |
| 18 | 530** | June-Reg | Jacob Coash | | P | 18 | 5/7/1984 | 6-4 | 220 | L | L | - | | Canyon High School (Canyon Country,CA) |
| 19 | 560 | June-Reg | Rafael Mendez | | 3B | 18 | 4/24/1984 | 6-0 | 190 | R | R | A+ | | Notre Dame High School (Caguas,PR) |
| 21 | 620 | June-Reg | Corey Loomis | | IF | 21 | 10/23/1980 | 6-1 | 180 | L | R | A- | | Bowling Green State University |
| 22 | 650** | June-Reg | Cameron McGuire | | C | 18 | 9/29/1983 | 6-3 | 205 | R | R | Ind | | South Grand Prairie High School (Grand Prairie,TX) |
| 27 | 800 | June-Reg | Damien Myers | | P | 21 | 11/3/1980 | 6-0 | 180 | L | R | A+ | | Concordia College (Mich.) |
| 28 | 830 | June-Reg | Everett Hancock | | P | 22 | 2/27/1980 | 6-0 | 180 | L | L | A- | | University of North Carolina |
| 29 | 860 | June-Reg | Miguel Donate | | 1B | | | | 0 | | | - | | Juan Quirindongo Morell (Vega Alta,PR) |
| 35 | 1040** | June-Reg | Brandon McCormick | | P | 18 | 12/27/1983 | 6-9 | 210 | R | R | - | | King Academy High School (Leesville,SC) |
| 36 | 1070 | June-Reg | Chris Steinborn | | P | 20 | 3/23/1982 | 6-4 | 210 | L | L | AA | | Lake Land College (Illinois) |
| 41 | 1220 | June-Reg | Edgar Ortiz | | 1B | 23 | 2/1/1979 | 6-3 | 220 | R | R | Rookie | | Compton Community College |
| 42 | 1250** | June-Reg | Travis Simmons | | 3B | 18 | 10/24/1983 | 6-2 | 180 | R | R | - | | Cleveland High School (Cleveland,TN) |
| 43 | 1279** | June-Reg | Corey McCoy | | OF | 18 | 8/30/1983 | 6-0 | 180 | R | R | - | | Pine Bluff High School (Pine Bluff,AR) |