| 653. | Jason Appel | OF | TB | 22 | 6/11/1986 | 6-1 | 185 | L-L | College | | University of North Carolina-Wilmington | 39 |
| 655. | Blaine Hardy | LHP | KC | 21 | 3/14/1987 | 6-2 | 195 | L-L | College | | Lewis-Clark State College | 98 |
| 656. | Patrick Kantakevich | RHP | BAL | 21 | 8/11/1986 | 6-2 | 210 | R-R | College | | College of William and Mary | 29 |
| 657. | Carter Bell | 3B | SF | 18 | 6/12/1990 | 6-2 | 185 | R-R | - | | Vanier High School (Toronto,ON) | 49 |
| 666. | Kyle Witten | RHP | MIN | 19 | 9/14/1988 | 6-4 | 175 | R-R | - | | Bakersfield Junior College | 72 |
| 671. | Tarlandas Mitchell | RHP | CHC | 18 | 3/9/1990 | 5-8 | 190 | R-R | - | | Alto High School (Alto,TX) | 1 |
| 672. | Blake Nation | RHP | SEA | 21 | 5/16/1987 | 6-8 | 218 | R-R | College | | Georgia Southern University | 81 |
| 673. | Zach MacPhee | SS | DET | 18 | 2/13/1990 | 5-9 | 170 | R-R | - | | O'Connor High School (Phoenix,AZ) | 50 |
| 674. | Chris Schwinden | RHP | NYM | 21 | 9/22/1986 | 6-3 | 190 | R-R | - | | Fresno Pacific University (Calif.) | 2 |
| 675. | Chris Wilkes | RHP | SD | 18 | 9/26/1989 | 6-4 | 235 | R-R | - | | Dr. Phillips High School (Orlando,FL) | 20 |
| 676. | Daniel Hargrave | 2B | PHI | 22 | 12/13/1985 | 6-0 | 178 | R-R | College | | University of North Carolina-Wilmington | 40 |
| 680. | Cory Arbiso | RHP | NYY | 22 | 4/21/1986 | 6-3 | 212 | R-R | College | | California State University, Fullerton | 246 |
| 681. | Bryce Stowell | RHP | CLE | 21 | 9/23/1986 | 6-2 | 205 | R-R | College | | University of California-Irvine | 59 |
| 682. | Anthony DeSclafani | RHP | BOS | 18 | 4/18/1990 | 6-1 | 175 | R-R | - | | Colts Neck High School (Colts Neck,NJ) | 51 |