| 623. | Ryan Carpenter | LHP | TB | 17 | 8/22/1990 | 6-5 | 205 | L-L | - | | Cactus High School (Glendale,AZ) | 3 |
| 624. | Brent Klinger | RHP | PIT | 19 | 7/21/1988 | 6-4 | 185 | R-R | - | | Glendale Community College (CA) | 37 |
| 625. | Jacob Theis | RHP | KC | 18 | 4/8/1990 | '6-6 | 220 | R-R | - | | Mountlake Terrace High School (Edmonds,WA) | 2 |
| 626. | Eddie Gamboa | RHP | BAL | 23 | 12/21/1984 | 6-2 | 195 | R-R | College | | University of California, Davis | 33 |
| 627. | Michael Eifel | RHP | SF | 22 | 8/13/1985 | 6-4 | 232 | R-R | - | | Dominican University (Illinois) | 1 |
| 629. | Theodis Bowe | OF | CIN | 17 | 8/5/1990 | 5-9 | 160 | L-R | - | | Milford High School (Milford,DE) | 47 |
| 630. | Drew Garcia | 2B | CHW | 22 | 4/22/1986 | 6-0 | 175 | S-R | College | | University of California-Riverside | 97 |
| 631. | Michael Guerrero | OF | WAN | 21 | 10/16/1986 | 6-0 | 190 | R-R | - | | University of Mississippi | 121 |
| 632. | Rodarrick Jones | OF | HOU | 17 | 7/31/1990 | 6-0 | 190 | R-R | - | | St. John High School (Plaquemine,LA) | 48 |
| 640. | Tyler Barnett | SS | ATL | 22 | 2/22/1986 | 5-9 | 175 | L-R | College | | Eastern Kentucky University | 28 |
| 641. | Logan Watkins | SS | CHC | 18 | 8/29/1989 | 5-11 | 170 | L-R | - | | Goddard High School (Goddard,KS) | 3 |
| 642. | Jordan Alvis | RHP | SEA | 22 | 9/16/1985 | 6-7 | 235 | R-R | College | | Middle Tennessee State University | 50 |
| 644. | James Fuller | LHP | NYM | 21 | 6/1/1987 | 5-10 | 175 | L-L | - | | Southern Connecticut State University | 6 |
| 645. | Joey Railey | 2B | SD | 22 | 12/9/1985 | 5-7 | 180 | L-R | College | | University of San Francisco | 65 |
| 646. | Sean Grieve | LHP | PHI | 23 | 12/13/1984 | 6-1 | 195 | L-L | College | | College of William and Mary | 28 |
| 647. | Tyler Trice | RHP | COL | 22 | 5/16/1986 | 6-4 | 205 | R-R | College | | University of North Carolina | 150 |
| 649. | Dwayne Bailey | 2B | LAA | 21 | 8/11/1986 | 6-2 | | S-R | College | | University of Central Florida | 81 |
| 652. | Jonathan Hee | 2B | BOS | 22 | 8/11/1985 | 6-0 | 180 | S-R | College | | University of Hawaii-Manoa | 88 |