| 47. | Kyle Lobstein | LHP | TB | 18 | 8/12/1989 | 6-3 | 200 | L-L | - | | Coconino High School (Flagstaff,AZ) | 2 |
| 49. | Johnny Giovatella | 2B | KC | 20 | 7/10/1987 | 5-8 | | R-R | - | | University of New Orleans | 78 |
| 50. | Xavier Avery | OF | BAL | 18 | 1/1/1990 | 5-11 | 180 | L-L | - | | Cedar Grove High School (Ellenwood,GA) | 5 |
| 51. | Anthony Gose | OF | PHI | 17 | 8/10/1990 | 6-1 | 190 | L-L | - | | Bellflower High School (Bellflower,CA) | 10 |
| 52. | Brad Hand | LHP | FLA | 18 | 3/20/1990 | 6-2 | 185 | L-L | - | | Chaska High School (Chaska,MN) | 3 |
| 55. | Destin Hood | OF | WAN | 18 | 4/3/1990 | 6-1 | 180 | R-R | - | | St. Paul's High School (Mobile,AL) | 3 |
| 56. | Jay Austin | OF | HOU | 17 | 8/10/1990 | 5-11 | 170 | L-L | - | | North Atlanta High School (Atlanta,GA) | 2 |
| 57. | Robbie Ross | LHP | TEX | 19 | 6/24/1989 | 5-11 | 185 | L-L | - | | Lexington Christian Academy High School (Lexington,KY) | 6 |
| 59. | Shane Peterson | OF | STL | 20 | 2/11/1988 | 6-0 | 195 | L-L | College | | Long Beach State University | 161 |
| 62. | Cody Adams | RHP | MIL | 21 | 11/26/1986 | 6-2 | 180 | R-R | College | | Southern Illinois University | 117 |
| 63. | Kenny Wilson | OF | TOR | 18 | 1/30/1990 | 6-0 | 165 | R-R | - | | Sickles High School (Tampa,FL) | 3 |
| 64. | Tyler Stovall | LHP | ATL | 18 | 12/27/1989 | 6-1 | 180 | L-L | - | | Hokes Bluff High School (Gadsden,AL) | 3 |
| 66. | Dennis Raben | OF | SEA | 20 | 7/31/1987 | 6-3 | 220 | L-L | College | | University of Miami (Florida) | 216 |
| 67. | Cody Satterwhite | RHP | DET | 21 | 1/27/1987 | 6-4 | 205 | R-R | College | | University of Mississippi | 117 |
| 69. | James Darnell | 3B | SD | 21 | 1/19/1987 | 6-2 | | R-R | College | | University of South Carolina | 138 |
| 70. | Zeke Spruill | RHP | ATL | 18 | 9/11/1989 | 6-4 | 184 | B-R | - | | Kell High School (Marietta,GA) | 2 |
| 73. | Bryan Shaw | RHP | ARI | 20 | 11/8/1987 | 6-1 | 215 | S-R | College | | Long Beach State University | 162 |
| 75. | Scott Bittle | RHP | NYY | 21 | 8/27/1986 | 6-1 | 190 | R-R | College | | University of Mississippi | 118 |
| 76. | Trey Haley | RHP | CLE | 18 | 6/21/1990 | 6-3 | 180 | R-R | - | | Central Heights High School (Nacogdoches,TX) | 7 |
| 77. | Derrik Gibson | SS | BOS | 18 | 12/5/1989 | 6-1 | 170 | R-R | - | | Seaford High School (Seaford,DE) | 4 |