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| 1. | Luke Hochevar | | P | Kansas City Royals | 22 | 9/15/1983 | 6-5 | 205 | R | R | MLB | 2007-2007 | | |
| 2. | Greg Reynolds | | P | Colorado Rockies | 20 | 7/3/1985 | 6-7 | 225 | R | R | AA | | Stanford University | 220 |
| 3. | Evan Longoria | | 3B | Tampa Bay Devil Rays | 20 | 10/7/1985 | 6-2 | 180 | R | R | AAA | | Long Beach State University | 151 |
| 4. | Brad Lincoln | | P | Pittsburgh Pirates | 21 | 5/25/1985 | 5-11 | 180 | L | R | A | | University of Houston | 98 |
| 5. | Brandon Morrow | | P | Seattle Mariners | 21 | 7/26/1984 | 6-3 | 175 | R | R | MLB | 2007-2007 | University of California | 156 |
| 6. | Andrew Miller | | P | Detroit Tigers | 21 | 5/21/1985 | 6-6 | 175 | L | L | MLB | 2006-2007 | University of North Carolina | 137 |
| 7. | Clayton Kershaw | | P | Los Angeles Dodgers | 18 | 3/19/1988 | 6-3 | 220 | L | L | AA | | Highland Park High School (Dallas,TX) | 1 |
| 8. | Drew Stubbs | | CF | Cincinnati Reds | 21 | 10/4/1984 | 6-5 | 190 | R | R | A | | University of Texas | 266 |
| 9. | William Rowell | | 3B | Baltimore Orioles | 17 | 9/10/1988 | 6-5 | 215 | L | R | A | | Bishop Eustace High School (Pennsauken,NJ) | 3 |
| 10. | Tim Lincecum | | P | San Francisco Giants | 22 | 6/15/1984 | 5-10 | 155 | L | R | MLB | 2007-2007 | University of Washington | 97 |
| 12. | Kasey Kiker | | P | Texas Rangers | 18 | 11/19/1987 | 5-11 | 185 | L | L | A | | Russell County High School (Seale,AL) | |
| 13. | Tyler Colvin | | LF | Chicago Cubs | 20 | 9/5/1985 | 6-3 | 190 | L | L | AA | | Clemson University | 165 |
| 14. | Travis Snider | | RF | Toronto Blue Jays | 18 | 2/2/1988 | 5-11 | 230 | L | L | A | | Jackson High School (Everett,WA) | |
| 15. | Christopher Marrero | | OF | Washington Nationals | 17 | 7/2/1988 | 6-3 | 210 | R | R | A+ | | Monsignor Pace High School (Opa Locka,FL) | 35 |
| 16. | Jeremy Jeffress | | P | Milwaukee Brewers | 18 | 9/21/1987 | 6-0 | 175 | R | R | A | | Halifax County High School (South Boston,VA) | |
| 17. | Matt Antonelli | | 3B | San Diego Padres | 21 | 4/8/1985 | 6-0 | 180 | R | R | AA | | Wake Forest University | 69 |
| 18. | Kyle Drabek | | P | Philadelphia Phillies | 18 | 12/8/1987 | 6-1 | 190 | R | R | A | | The Woodlands High School (The Woodlands,TX) | 4 |
| 19. | Brett Sinkbeil | | P | Florida Marlins | 21 | 12/26/1984 | 6-4 | 185 | R | R | A+ | | Southwest Missouri State University | 70 |
| 20. | Christopher Parmelee | | RF | Minnesota Twins | 18 | 2/24/1988 | 6-1 | 205 | L | L | A | | Chino Hills High School (Chino Hills,CA) | |
| 21. | Ian Kennedy | | P | New York Yankees | 21 | 12/19/1984 | 5-11 | 185 | R | R | MLB | 2007-2007 | USC | 275 |
| 22. | Colton Willems | | P | Washington Nationals | 17 | 7/30/1988 | 6-4 | 175 | R | R | A- | | John Carroll High School (Fort Pierce,FL) | 10 |
| 23. | Maxwell Sapp | | C | Houston Astros | 18 | 2/21/1988 | 6-2 | 220 | L | R | A | | Bishop Moore High School (Orlando,FL) | 8 |
| 24. | John Johnson | | OF | Atlanta Braves | 17 | 8/18/1988 | 6-4 | 195 | L | R | - | | Mosley High School (Panama City,FL) | 13 |
| 25. | Hank Conger | | C | Los Angeles Angels | 18 | 1/29/1988 | 6-0 | 205 | B | R | A | | Huntington Beach High School (Huntington Beach,CA) | 13 |
| 26. | Bryan Morris | | P | Los Angeles Dodgers | 19 | 3/28/1987 | 6-3 | 175 | L | R | Rookie | | Motlow State Community College | 20 |
| 27. | Jason Place | | CF | Boston Red Sox | 18 | 5/8/1988 | 6-3 | 205 | R | R | AA | | Wren High School (Piedmont,SC) | |
| 28. | Daniel Bard | | P | Boston Red Sox | 21 | 6/25/1985 | 6-4 | 185 | R | R | AA | | University of North Carolina | 138 |
| 29. | Kyle McCulloch | | P | Chicago White Sox | 21 | 3/20/1985 | 6-2 | 170 | R | R | AA | | University of Texas | 267 |
| 30. | Adam Ottavino | | P | St. Louis Cardinals | 20 | 11/22/1985 | 6-4 | | B | R | A+ | | Northeastern University | 28 |
| 31. | Preston Mattingly | | SS | Los Angeles Dodgers | 18 | 8/28/1987 | 6-3 | 205 | R | R | A | | Evansville Central High School (Evansville,IN) | 3 |
| 32. | Pedro Beato | | P | Baltimore Orioles | 19 | 10/27/1986 | 6-5 | 210 | R | R | A | | St. Petersburg College | 78 |
| 33. | Emmanuel Burris | | SS | San Francisco Giants | 21 | 1/17/1985 | 6-0 | 170 | B | R | A- | | Kent State University | 59 |
| 34. | Brooks Brown | | P | Arizona Diamondbacks | 21 | 6/20/1985 | 6-3 | 205 | L | R | College | | University of Georgia | 88 |
| 35. | Kyler Burke | | RF | San Diego Padres | 18 | 4/20/1988 | 6-3 | 205 | L | L | A | | Ooltewah High School (Ooltewah,TN) | |
| 36. | Chris Coghlan | | 3B | Florida Marlins | 21 | 6/18/1985 | 6-1 | 190 | L | R | A+ | | University of Mississippi | 105 |
| 37. | Adrian Cardenas | | SS | Philadelphia Phillies | 18 | 10/10/1987 | 6-0 | 185 | L | R | A | | Monsignor Pace High School (Opa Locka,FL) | 36 |
| 38. | Cory Rasmus | | P | Atlanta Braves | 18 | 11/6/1987 | 6-0 | 200 | R | R | Rookie | | Russell County High School (Seale,AL) | |
| 39. | David Huff | | P | Cleveland Indians | 21 | 8/22/1984 | 6-2 | 185 | B | L | A+ | | UCLA | 201 |
| 40. | Kris Johnson | | P | Boston Red Sox | 21 | 10/14/1984 | 6-4 | 170 | L | L | A+ | | Wichita State University | 129 |
| 41. | Joba Chamberlain | | P | New York Yankees | 20 | 9/23/1985 | 6-3 | 225 | R | R | MLB | 2007-2007 | University of Nebraska | 123 |
| 42. | Chris Perez | | P | St. Louis Cardinals | | | | | | | AAA | | University of Miami (Florida) | 200 |
| 43. | Steven Evarts | | P | Atlanta Braves | 18 | 10/13/1987 | 6-3 | 180 | L | L | Rookie | | Robinson High School (Tampa,FL) | 11 |
| 44. | Caleb Clay | | P | Boston Red Sox | 18 | 2/15/1988 | 6-2 | 180 | R | R | A- | | Cullman High School (Cullman,AL) | |
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