| 139. | Shawn O'Malley | SS | TB | 18 | 12/28/1987 | 5-10 | 155 | R-R | A- | | Southridge High School (Kennewick,WA) | 2 |
| 141. | Nathan Adcock | P | SEA | 18 | 2/25/1988 | 6-5 | 190 | R-R | A+ | | North Hardin High School (Elizabethtown,KY) | |
| 142. | Scott Sizemore | 2B | DET | 21 | 1/4/1985 | 6-0 | 185 | R-R | A | | Virginia Commonwealth University | 34 |
| 143. | Kyle Smit | P | LA | 18 | 10/14/1987 | 6-2 | 175 | R-R | A | | Spanish Springs High School (Sparks,NV) | |
| 144. | Joshua Ravin | P | CIN | 18 | 1/21/1988 | 6-5 | 210 | R-R | Rookie | | Chatsworth High School (Chatsworth,CA) | 19 |
| 145. | Bobby Henson | SS | BAL | 18 | 12/15/1987 | 6-1 | 0 | R-R | A+ | | Tuttle High School (Tuttle,OK) | |
| 146. | Michael McBryde | CF | SF | 21 | 3/22/1985 | 6-1 | 170 | R-R | A | | Florida Atlantic University | 48 |
| 150. | Luke Hopkins | 1B | TOR | 21 | 4/15/1985 | 6-2 | 240 | L-R | A- | | New Mexico State University | 51 |
| 156. | Devin Shepherd | RF | MIN | 18 | 9/9/1987 | 6-3 | 225 | R-R | College | | Oxnard High School (Oxnard,CA) | 5 |
| 157. | Quintin Berry | CF | PHI | 21 | 11/21/1984 | 6-1 | 165 | L-L | A | | San Diego State University | 167 |
| 159. | Casey Hudspeth | P | HOU | 21 | 10/1/1984 | 5-11 | 165 | R-R | A+ | | University of South Florida | 86 |
| 161. | Christopher Archer | P | CLE | 17 | 9/26/1988 | 6-2 | 165 | R-R | A | | Clayton High School (Clayton,NC) | |
