| 45. | Jason Taylor | SS | KC | 18 | 1/14/1988 | 6-0 | 200 | R-R | Rookie | | Kellam High School (Virginia Beach,VA) | 4 |
| 46. | David Christensen | OF | COL | 18 | 2/11/1988 | 6-1 | 195 | R-R | Rookie | | Douglas High School (Parkland,FL) | |
| 51. | Jeffrey Locke | P | ATL | 18 | 11/20/1987 | 6-2 | 180 | L-L | Rookie | | Kennett Conway High School (Conway,NH) | |
| 53. | Chad Huffman | 2B | SD | 21 | 4/29/1985 | 6-1 | 205 | R-R | AA | | Texas Christian University | 78 |
| 54. | Brad Furnish | P | STL | 21 | 1/19/1985 | 6-1 | 185 | B-L | A+ | | Texas Christian University | 79 |
| 56. | Steven Wright | P | CLE | 21 | 8/30/1984 | 6-1 | 200 | R-R | A+ | | University of Hawaii-Manoa | 80 |
| 58. | Ryan Adams | 3B | BAL | 19 | 4/21/1987 | 6-0 | 185 | R-R | A- | | Jesuit High School (New Orleans,LA) | 7 |
| 59. | Sean Black | P | WAN | 18 | 4/23/1988 | 6-3 | 185 | R-R | College | | Lenape High School (Medford,NJ) | 5 |
| 60. | Brent Brewer | SS | MIL | 18 | 12/19/1987 | 6-2 | 190 | R-R | A | | Sandy Creek High School (Tyrone,GA) | |
| 63. | Thomas Hickman | CF | FLA | 18 | 4/18/1988 | 6-1 | 175 | L-L | A- | | Pepperell High School (Lindale,GA) | |
| 65. | Andrew Carpenter | P | PHI | 21 | 5/18/1985 | 6-3 | 230 | R-R | A+ | | Long Beach State University | 152 |
| 66. | Trevor Cahill | P | OAK | 18 | 3/1/1988 | 6-3 | 195 | R-R | A | | Vista High School (Vista,CA) | 10 |
| 68. | Dustin Evans | P | ATL | 21 | 9/24/1984 | 6-3 | 200 | R-R | A+ | | Georgia Southern University | 76 |
| 70. | Stephen Englund | OF | WAN | 18 | 6/6/1988 | 6-3 | 200 | R-R | A- | | Bellevue High School (Bellevue,WA) | |
| 71. | Justin Masterson | P | BOS | 21 | 3/22/1985 | 6-6 | 235 | R-R | AA | | San Diego State University | 166 |
| 72. | Chase Fontaine | SS | ATL | 20 | 10/22/1985 | 6-2 | 185 | L-R | A+ | | Daytona Beach Community College | 7 |
