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| 1. | Matt Bush | $$ | SS | San Diego Padres | 18 | 2/8/1986 | 5-11 | 170 | R | R | A+ | | Mission Bay High School (San Diego,CA) | 20 |
| 2. | Justin Verlander | $$ | P | Detroit Tigers | 21 | 2/20/1983 | 6-5 | 200 | R | R | MLB | 2005-2007 | Old Dominion University | 46 |
| 3.** | Philip Humber | | P | New York Mets | 21 | 12/21/1982 | 6-4 | 210 | R | R | MLB | 2006-2007 | Rice University | 97 |
| 4.** | Jeff Niemann | | P | Tampa Bay Devil Rays | 21 | 2/28/1983 | 6-9 | 260 | R | R | AAA | | Rice University | 98 |
| 5. | Mark Rogers | $$ | P | Milwaukee Brewers | 18 | 1/30/1986 | 6-2 | 205 | R | R | A+ | | Mount Ararat High School (Topsham,ME) | 1 |
| 6. | Jeremy Sowers | $$ | P | Cleveland Indians | 21 | 5/17/1983 | 6-1 | 165 | L | L | MLB | 2006-2007 | Vanderbilt University | 68 |
| 7. | Homer Bailey | $$ | P | Cincinnati Reds | 18 | 5/3/1986 | 6-4 | 185 | R | R | MLB | 2007-2007 | La Grange High School (La Grange,TX) | 3 |
| 8.** | Wade Townsend | | P | Baltimore Orioles | 21 | 2/22/1983 | 6-4 | 230 | R | R | A | | Rice University | 99 |
| 9. | Christopher Nelson | $$ | SS | Colorado Rockies | 18 | 9/3/1985 | 5-11 | 176 | R | R | A+ | | Redan High School (Stone Mountain,GA) | 7 |
| 10. | Thomas Diamond | $$ | P | Texas Rangers | 21 | 4/6/1983 | 6-3 | 230 | R | R | AA | | University of New Orleans | 72 |
| 11. | Neil Walker | $$ | C | Pittsburgh Pirates | 18 | 9/10/1985 | 6-3 | 205 | B | R | AAA | | Pine Richland High School (Gibsonia,PA) | 1 |
| 12. | Jered Weaver | $$ | P | Anaheim Angels | 21 | 10/4/1982 | 6-7 | 205 | R | R | MLB | 2006-2007 | Long Beach State University | 135 |
| 13. | Bill Bray | $$ | P | Montreal Expos | 21 | 6/5/1983 | 6-3 | 215 | L | L | MLB | 2006-2007 | College of William and Mary | 19 |
| 14. | Billy Butler | $$ | 3B | Kansas City Royals | 18 | 4/18/1986 | 6-2 | 225 | R | R | MLB | 2007-2007 | Wolfson High School (Jacksonville,FL) | 5 |
| 15. | Stephen Drew | $$ | SS | Arizona Diamondbacks | 21 | 3/16/1983 | 6-1 | 195 | L | R | MLB | 2006-2007 | Florida State University | 175 |
| 16. | David Purcey | $$ | P | Toronto Blue Jays | 22 | 4/22/1982 | 6-5 | 240 | L | L | AAA | | University of Oklahoma | 181 |
| 17. | Scott Elbert | $$ | P | Los Angeles Dodgers | 18 | 8/13/1985 | 6-2 | 190 | L | L | AA | | Seneca High School (Seneca,MO) | 1 |
| 18. | Josh Fields | $$ | 3B | Chicago White Sox | 21 | 12/14/1982 | 6-2 | 210 | R | R | MLB | 2006-2007 | Oklahoma State University | 171 |
| 19. | Chris Lambert | $$ | P | St. Louis Cardinals | 21 | 3/8/1983 | 6-1 | 205 | R | R | AAA | | Boston College | 23 |
| 20. | Trevor Plouffe | $$ | SS | Minnesota Twins | 18 | 6/15/1986 | 6-1 | 175 | R | R | AA | | Crespi Carmelite High School (Encino,CA) | 14 |
| 21. | Greg Golson | $$ | OF | Philadelphia Phillies | 18 | 9/17/1985 | 6-0 | 190 | R | R | AA | | Connally High School (Austin,TX) | 3 |
| 22. | Glen Perkins | $$ | P | Minnesota Twins | 21 | 3/2/1983 | 5-11 | 190 | L | L | MLB | 2006-2007 | University of Minnesota | 113 |
| 23. | Philip Hughes | $$ | P | New York Yankees | 18 | 6/24/1986 | 6-5 | 220 | R | R | MLB | 2007-2007 | Foothill High School (Santa Ana,CA) | 6 |
| 24. | Landon Powell | $$ | C | Oakland Athletics | 22 | 3/19/1982 | 6-3 | 230 | B | R | AAA | | University of South Carolina | 110 |
| 25. | Kyle Waldrop | $$ | P | Minnesota Twins | 18 | 10/27/1985 | 6-4 | 190 | R | R | AA | | Farragut High School (Knoxville,TN) | 4 |
| 26. | Richie Robnett | $$ | OF | Oakland Athletics | 20 | 9/17/1983 | 5-10 | 195 | L | L | AAA | | Fresno State University | 160 |
| 27. | Taylor Tankersley | $$ | P | Florida Marlins | 21 | 3/7/1983 | 6-1 | 220 | L | L | MLB | 2006-2007 | University of Alabama | 98 |
| 28. | Blake DeWitt | $$ | SS | Los Angeles Dodgers | 18 | 8/20/1985 | 5-11 | 175 | L | R | AA | | Sikeston High School (Sikeston,MO) | 1 |
| 29. | Matt Campbell | $$ | P | Kansas City Royals | 21 | 12/27/1982 | 6-2 | 170 | L | L | A+ | | University of South Carolina | 111 |
| 30. | Eric Hurley | $$ | P | Texas Rangers | 18 | 9/17/1985 | 6-4 | 195 | R | R | AAA | | Wolfson High School (Jacksonville,FL) | 6 |
| 31. | J.P. Howell | $$ | P | Kansas City Royals | 21 | 4/25/1983 | 6-0 | 180 | L | L | MLB | 2005-2007 | University of Texas | 250 |
| 32. | Zach Jackson | $$ | P | Toronto Blue Jays | 21 | 5/13/1983 | 6-5 | 220 | L | L | MLB | 2006-2006 | Texas A&M University | 161 |
| 33. | Justin Orenduff | $$ | P | Los Angeles Dodgers | 21 | 5/27/1983 | 6-4 | 205 | R | R | AA | | Virginia Commonwealth University | 29 |
| 34. | Tyler Lumsden | $$ | P | Chicago White Sox | 21 | 5/9/1983 | 6-4 | 200 | R | L | AAA | | Clemson University | 151 |
| 35. | Matt Fox | $$ | P | Minnesota Twins | 21 | 12/4/1982 | 6-3 | 192 | R | R | A | | University of Central Florida | 66 |
| 36. | Danny Putnam | $$ | OF | Oakland Athletics | 21 | 9/17/1982 | 5-11 | 198 | L | L | MLB | 2007-2007 | Stanford University | 204 |
| 37. | Jon Poterson | $$ | C | New York Yankees | 18 | 2/10/1986 | 6-1 | 215 | B | R | A | | Chandler High School (Chandler,AZ) | 13 |
| 38. | Giovany Gonzalez | $$ | P | Chicago White Sox | 18 | 9/19/1985 | 5-11 | 185 | R | L | AA | | Monsignor Pace High School (Opa Locka,FL) | 29 |
| 39. | Jay Rainville | $$ | P | Minnesota Twins | 18 | 10/16/1985 | 6-3 | 230 | R | R | A+ | | Bishop Hendricken High School (Warwick,RI) | 4 |
| 40. | Huston Street | $$ | P | Oakland Athletics | 20 | 8/2/1983 | 6-0 | 185 | R | R | MLB | 2005-2007 | University of Texas | 251 |
| 41. | Jeff Marquez | $$ | P | New York Yankees | 19 | 8/10/1984 | 6-2 | 175 | R | R | AA | | Sacramento City College | 239 |
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