| 164. | Ryan Coultas | SS | NYM | 22 | 4/24/1982 | 6-3 | 180 | R-R | AA | | University of California, Davis | 23 |
| 165. | Ryan Royster | OF | TB | 17 | 7/25/1986 | 6-2 | 205 | R-R | A+ | | Churchill High School (Eugene,OR) | 3 |
| 166. | Stephen Chapman | OF | MIL | 18 | 10/12/1985 | 6-0 | 180 | L-L | A+ | | Marianna High School (Marianna,FL) | 5 |
| 169. | Bryce Chamberlin | P | BAL | 21 | 12/22/1982 | 6-2 | 195 | R-R | A | | Washington State University | 119 |
| 172. | A.J. Johnson | OF | PIT | 20 | 9/26/1983 | 6-1 | 190 | R-R | A | | Tallahassee Community College | 26 |
| 174. | Devin Ivany | C | MTL | 21 | 7/27/1982 | 6-1 | 178 | R-R | AA | | University of South Florida | 80 |
| 175. | Chad Blackwell | P | KC | 21 | 1/7/1983 | 6-1 | 145 | B-R | AA | | University of South Carolina | 114 |
| 178. | Dan Batz | 1B | LA | 22 | 3/19/1982 | 6-1 | 195 | R-R | A | | University of Rhode Island | 13 |
| 180. | Jarrett Hoffpauir | 2B | STL | 21 | 6/18/1983 | 5-9 | 165 | R-R | AAA | | University of Southern Mississippi | 53 |
| 181. | Patrick Bryant | P | MIN | 18 | 10/26/1985 | 6-4 | 190 | R-R | Rookie | | Pensacola Catholic High School (Pensacola,FL) | 4 |
| 183. | Jermaine Brock | OF | SEA | 17 | 1/29/1987 | 6-2 | 175 | L-L | Rookie | | Ottawa Hills High School (Grand Rapids,MI) | 4 |
| 184. | Ben Zobrist | 2B | HOU | 23 | 5/26/1981 | 6-3 | 200 | B-R | MLB | 2006-2008 | Dallas Baptist University | 60 |
| 185. | Cla Meredith | P | BOS | 21 | 6/4/1983 | 6-0 | 180 | R-R | MLB | 2005-2008 | Virginia Commonwealth University | 30 |
| 189. | Nate Phillips | SS | NYY | 18 | 1/24/1986 | 6-2 | 190 | B-R | Rookie | | Grace Prep Academy High School (Arlington,TX) | 2 |