| 373. | Brooks Colvin | 3B | DET | 22 | 12/11/1981 | 5-10 | 170 | R-R | A | | Southwest Missouri State University | 67 |
| 376. | Angel Ayala | 1B | MIL | 17 | 7/24/1986 | 6-2 | 208 | L-R | Rookie | | Lino Padron Rivera High School (Vega Baja,PR) | 2 |
| 377. | Jason Denham | OF | CLE | 18 | 5/1/1986 | 6-0 | 170 | L-L | A+ | | Deer Valley High School (Antioch,CA) | 4 |
| 381. | Kyle Rogers | P | TEX | 18 | 9/23/1985 | 6-3 | 190 | R-R | A | | Ball High School (Galveston,TX) | 6 |
| 382. | Brett Grandstrand | 2B | PIT | 21 | 11/13/1982 | 6-0 | 175 | R-R | A | | Coastal Carolina University | 35 |
| 384. | David Travis | 2B | MTL | 23 | 12/15/1980 | 6-4 | 210 | L-R | A- | | Southern Wesleyan University (S.C.) | 1 |
| 385. | Travis Trammell | P | KC | 22 | 8/19/1981 | 6-5 | 240 | R-R | Rookie | | University of Arkansas-Little Rock | 8 |
| 390. | Daniel Nelson | SS | STL | 20 | 2/12/1984 | 5-11 | 180 | B-R | A+ | | Los Angeles Pierce College | 86 |
| 391. | Walter Patton | P | MIN | 19 | 3/13/1985 | 6-1 | 190 | R-R | Rookie | | Lincoln Land Community College | 29 |
| 392. | James Adkins | P | PHI | 18 | 11/26/1985 | 6-5 | 195 | L-L | A+ | | Wilson Central High School (Lebanon,TN) | 1 |
| 398. | Steve Gendron | SS-3B | FLA | 22 | 11/25/1981 | 6-3 | 199 | R-R | AAA | | Mississippi State University | 128 |
| 399. | P.J. Pilittere | C | NYY | 22 | 11/23/1981 | 6-0 | 215 | R-R | AA | | California State University, Fullerton | 208 |
| 401. | Todd Blackford | P | ATL | 19 | 6/10/1985 | 6-3 | 200 | L-R | A+ | | Triton High School (Bourbon,IN) | 1 |