| 1 | 20 | June-Reg | Chad Cordero | P | 21 | 6-0 | 195 | R | R | MLB | 2003-2008 | Cal State Fullerton | $1,350,000 |
| 2 | 57 | June-Reg | Jerry Owens | OF | 22 | 6-3 | 195 | L | L | MLB | 2006-2009 | Master's College, The | $600,000 |
| 3 | 87 | June-Reg | Kory Casto | OF | 21 | 6-0 | 190 | L | R | MLB | 2007-2008 | University of Portland | $410,000 |
| 4 | 117 | June-Reg | Edgardo Baez | OF | 17 | 6-2 | 190 | R | R | AA | | Jose S. Alegria (Jose S. Alegria,Dorado,PR) | $250,000 |
| 5 | 147 | June-Reg | Trey Webb | SS | 21 | 6-0 | 170 | R | R | AA | | Baylor University | $180,000 |
| 6 | 177 | June-Reg | Josh Whitesell | 1B | 21 | 6-3 | 220 | L | L | MLB | 2008-2009 | Loyola Marymount University | $120,000 |
| 7 | 207 | June-Reg | Devin Perrin | P | 22 | 6-7 | 225 | R | R | AAA | | Grand Canyon University | $25,000 |
| 8 | 237 | June-Reg | Daryl Thompson | P | 17 | 6-1 | 170 | R | R | MLB | 2008-2008 | La Plata (La Plata,MD) | $80,000 |
| 9 | 267 | June-Reg | Gabriel Sosa | P | 17 | 5-9 | 170 | L | L | A- | | Lino Padron Rivera (Vega Baja,PR) | $60,000 |
| 10 | 297 | June-Reg | Victor Hamisevicz | 1B | 18 | 6-4 | 190 | L | L | Rookie | | Gonzaga College Prep (Washington,DC) | $50,000 |
| 11 | 327 | June-Reg | Aaron Wideman | P | 18 | 5-11 | 200 | R | L | AA | | Streetsville (Mississauga,ON) | |
| 12 | 357 | June-Reg | Mike St. Martine | C | 21 | 5-11 | 195 | L | R | A | | Monmouth College | |
| 13 | 387 | June-Reg | Brad Ditter | 2B | 22 | 6-0 | 180 | L | R | AA | | New Mexico State University | |
| 14 | 417 | June-Reg | Larry York | 2B | 23 | 5-10 | 180 | B | R | A | | Liberty University | |
| 15 | 447 | June-Reg | Brett Reid | P | 23 | 5-11 | 200 | R | R | A+ | | Avila University | |
| 16 | 477 | June-Reg | Rickey Jenkins | P | 21 | 6-4 | 185 | R | R | A- | | | |
| 17 | 507 | June-Reg | Luke Montz | C | 19 | 6-2 | 205 | R | R | MLB | 2008-2008 | Hill College | |
| 18 | 537 | June-Reg | Eduardo Nunez | SS | 17 | 6-2 | 170 | R | R | A | | American Military Academy (San Juan,PR) | |
| 19 | 567 | June-Reg | Jeremy Plexico | P | 23 | 6-4 | 210 | L | L | AA | | Winthrop University | |
| 20 | 597 | June-Reg | Terry Engles | P | 17 | 6-4 | 170 | R | R | A+ | | St. Peters Boys (Staten Island,NY) | |
| 21 | 627** | June-Reg | Joe Bisenius | P | 20 | 6-5 | 210 | R | R | MLB | 2007-2007 | Iowa Western Community College | |
| 22 | 657 | June-Reg | Gus Hlebovy | P | 20 | 6-0 | 165 | R | R | A | | Kent State University | |
| 23 | 687** | June-Reg | Brett Cooley | 1B | 22 | 6-4 | 220 | R | R | Ind | | University of Houston | |
| 24 | 717** | June-Reg | Jon Hunton | P | 20 | 6-9 | 230 | R | R | AA | | Hutchinson Community College | |
| 25 | 747 | June-Reg | James Russell | P | 22 | 6-6 | 240 | R | R | A- | | Villanova University | |
| 26 | 777 | June-Reg | Jim Henderson | P | 20 | 6-4 | 190 | R | R | AAA | | Tennessee Wesleyan College | |
| 27 | 807 | June-Reg | Bret Pignatiello | C | 22 | 6-2 | 200 | L | R | A- | | Eastern Illinois University | |
| 28 | 837 | June-Reg | Oscar Bernazard | 2B | 22 | 5-10 | 195 | B | R | A+ | | Lindenwood University | |
| 29 | 867 | June-Reg | Jamie Lehman | P | 18 | 6-1 | 185 | R | R | A+ | | Notre Dame (Brampton,ON) | |
| 30 | 897 | June-Reg | Matt Buck | P | 18 | 6-2 | 180 | L | L | College | | Cactus Shadows (Cave Creek,AZ) | |
| 31 | 927 | June-Reg | Chris Hufft | P | 17 | 6-3 | 210 | R | R | - | | West Hills (Santee,CA) | |
| 32 | 957 | June-Reg | B.J. Weidenbach | OF | 19 | 6-4 | 220 | R | R | - | | Fresno City College | |
| 33 | 987** | June-Reg | Gabe Suarez | SS | 18 | 6-0 | 185 | R | R | A+ | | Arcadia (Phoenix,AZ) | |
| 34 | 1017 | June-Reg | Matt Montgomery | P | 18 | 6-0 | 215 | R | R | - | | Watkins Mill (Gaithersburg,MD) | |
| 35 | 1047 | June-Reg | Doug Vroman | OF | 22 | 6-2 | 200 | R | R | AA | | University of New Haven | |
| 36 | 1077 | June-Reg | Konrad Thieme | P | 18 | 6-3 | 205 | R | R | A+ | | Westlake (Westlake Village,CA) | |
| 37 | 1107** | June-Reg | Brendan Murphy | 1B | 18 | 6-3 | 210 | R | R | Ind | | Grace Baptist Academy (Chattanooga,TN) | |
| 38 | 1137 | June-Reg | Seth Bynum | SS | 22 | 6-0 | 180 | R | R | AAA | | Indiana University | |
| 39 | 1167 | June-Reg | Trent Kline | C | 18 | 5-9 | 160 | B | R | A+ | | West York Area (York,PA) | |
| 40 | 1197 | June-Reg | Jacob Cook | P | 18 | 6-1 | 195 | R | L | Rookie | | Lee-Davis (Mechanicsville,VA) | |
| 41 | 1227 | June-Reg | Jonathan Kalkau | P | 18 | 6-1 | 215 | R | R | College | | Holy Trinity (Hicksville,NY) | |
| 42 | 1256 | June-Reg | Scott Rogowski | P | 19 | 6-5 | 190 | R | R | - | | White County (Doyle,TN) | |
| 43 | 1285 | June-Reg | Anthony Savio | P | 18 | 6-4 | 195 | R | R | - | | American River College | |
| 44 | 1313** | June-Reg | Mike Ambort | C | 18 | 6-1 | 215 | B | R | A+ | | South Side (Rockville Centre,NY) | |
| 45 | 1340 | June-Reg | Sean O'Brien | 1B | 18 | 6-1 | 215 | L | L | College | | Horace Greeley (Chappaqua,NY) | |
| 46 | 1367 | June-Reg | Alex Morales | P | 20 | 5-11 | 165 | R | R | AAA | | Oakton Community College | |
| 47 | 1394 | June-Reg | Steven Romero | P | 18 | 6-5 | 200 | R | R | - | | Mount San Antonio College | |
| 48 | 1421 | June-Reg | Lance Zawadzki | SS | 18 | 5-11 | 185 | B | R | AA | | St. John's (Shrewsbury,MA) | |
| 49 | 1447 | June-Reg | Kyle Nicholson | P | 17 | 5-11 | 205 | R | R | A+ | | A&M Consolidated (College Station,TX) | |
| 50 | 1473** | June-Reg | Mike James | P | 22 | 6-0 | 190 | R | R | AA | | University of Connecticut | |
