| # | Player Name | Pos | Team | Age | Born | Ht | Wt | B-T | High Level | MLB Years | Drafted From | # |
| 161. | Will Smith | OF | FLA | 18 | 10/23/1981 | 6-1 | 185 | L-R | AAA | - | Palo Verde High School (Tucson,AZ) | 5 |
| 162. | Ronnie Corona | P | MIN | 21 | 1/27/1979 | 6-0 | 188 | R-R | AA | | California State University, Fullerton | 176 |
| 163. | J.J. Johnson | P | CHC | 18 | 11/3/1981 | 6-2 | 195 | R-R | AA | | Greenbrier High School (Evans,GA) | 2 |
| 164. | Brian Bass | P | KC | 18 | 1/6/1982 | 6-1 | 195 | R-R | MLB | 2008-2008 | Robert E. Lee High School (Montgomery,AL) | 9 |
| 165. | Shawn Hill | P | MTL | 19 | 4/28/1981 | 6-2 | 185 | R-R | MLB | 2004-2008 | Bishop PF Reding High School (Georgetown,ON) | 2 |
| 166. | Dan Massiatte | C | TB | 21 | 7/25/1978 | 5-11 | 181 | R-R | AA | | University of Louisiana-Lafayette | 53 |
| 167. | Scott Dohmann | P | COL | 22 | 2/13/1978 | 6-1 | 181 | R-R | MLB | 2004-2008 | University of Louisiana-Lafayette | 54 |
| 168. | Matt Parris | P | DET | 17 | 10/4/1982 | 6-3 | 190 | R-R | Ind | | Highland High School (Palmdale,CA) | 3 |
| 169. | Ryan Earey | P | SD | 21 | 3/5/1979 | 6-4 | 225 | R-R | A | | University of North Carolina | 108 |
| 170. | Brandon O'Neal | P | ANA | 21 | 10/17/1978 | 6-1 | 195 | B-R | AA | | University of Kansas | 61 |
| 171. | Brian Hicks | CF | MIL | 18 | 6/28/1982 | 6-3 | 195 | L-R | Rookie | | Natchitoches Central High School (Natchitoches,LA) | 1 |
| 172. | Bjorn Ivy | OF | CHW | 18 | 9/20/1981 | 5-10 | 170 | R-R | A | | Shannon High School (Shannon,MS) | 2 |
| 173. | Justin Woodrow | LF | STL | 18 | 3/26/1982 | 6-2 | 195 | L-R | A- | | Knoch High School (Saxonburg,PA) | 3 |
| 174. | Brandon Spillers | P | BAL | 18 | 3/12/1982 | 6-3 | 210 | R-L | A | | Tattnall Square Academy High School (Macon,GA) | 2 |
| 175. | Taylor Buchholz | P | PHI | 18 | 10/13/1981 | 6-4 | 220 | R-R | MLB | 2006-2008 | Springfield High School (Springfield,PA) | 4 |
| 176. | Jamal Strong | OF | SEA | 21 | 8/5/1978 | 5-10 | 180 | R-R | MLB | 2003-2005 | University of Nebraska | 89 |
| 177. | Greg Withelder | P | LA | 21 | 5/11/1979 | 6-3 | 200 | R-L | A+ | | Wilmington College (Delaware) | 4 |
| 178. | Mike Thompson | H | TOR | 19 | 11/6/1980 | 6-4 | 200 | R-R | MLB | 2006-2007 | James Madison University | 52 |
| 179. | Josh Shortslef | P | PIT | 18 | 2/1/1982 | 6-4 | 230 | R-L | AA | | Hannibal High School (Hannibal,NY) | 1 |
| 180. | Beau Craig | C | OAK | 21 | 2/12/1979 | 5-10 | 170 | B-R | AAA | | USC | 246 |
| 181. | Chad Ashlock | P | SF | 21 | 7/17/1978 | 6-2 | 200 | R-R | A- | | Southern Nazarene University (Okla.) | 1 |
| 182. | Kenny Perez | IF | BOS | 18 | 9/28/1981 | 6-2 | 195 | B-R | AAA | | South Miami High School (Miami,FL) | 6 |
| 183. | Ryan Mottl | P | CIN | 22 | 12/9/1977 | 6-3 | 190 | B-R | AAA | | Clemson University | 135 |
| 184. | Matt Meisenheimer | P | TEX | 18 | 10/1/1981 | 6-3 | 180 | R-R | A | | Greenville High School (Greenville,TX) | 1 |
| 185. | Chris Basak | SS | NYM | 21 | 12/6/1978 | 6-2 | 185 | R-R | MLB | 2007-2007 | University of Illinois | 63 |
| 186. | Kyle Evans | P | CLE | 21 | 10/10/1978 | 6-3 | 190 | R-R | AAA | | Baylor University | 61 |
| 187. | Tommy Whiteman | SS | HOU | 20 | 7/14/1979 | 6-3 | 175 | R-R | AAA | | University of Oklahoma | 164 |
| 188. | Jeremy King | P | NYY | 18 | 11/12/1981 | 6-2 | 210 | R-R | AAA | | DeSoto County High School (Nocatee,FL) | 1 |
| 189. | Robert Barber | P | ARI | | | | 0 | - | - | | University of South Carolina | 86 |
| 190. | Matt Merricks | P | ATL | 17 | 8/6/1982 | 5-11 | 180 | L-L | AA | | Oxnard High School (Oxnard,CA) | 2 |
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