| 371. | Phil Akens | P | FLA | 17 | 8/9/1982 | 6-6 | 200 | R-R | A+ | | Fallston High School (Fallston,MD) | 1 |
| 373. | Jeremy Flanagan | P | CHC | 19 | 4/14/1981 | 6-3 | 215 | R-R | AA | | San Lorenzo High School (Felton,CA) | 2 |
| 379. | Justin Germano | P | SD | 17 | 8/6/1982 | 6-2 | 190 | R-R | MLB | 2004-2008 | Claremont High School (Claremont,CA) | 11 |
| 380. | Josh Gray | 1B | ANA | 19 | 2/22/1981 | 6-3 | 210 | R-R | Ind | | Rock Creek High School (Durant,OK) | 1 |
| 381. | Matt Yeatman | P | MIL | 17 | 8/2/1982 | 6-4 | 230 | R-R | AA | | Tomball High School (Tomball,TX) | 1 |
| 385. | Carlos Rivera | 1B | PHI | 22 | 6/10/1978 | 6-1 | 245 | L-L | MLB | 2003-2004 | Santo Tomas De Aquino High School (Toa Baja,PR) | |
| 387. | Ronte Langs | OF | LA | 21 | 1/29/1979 | 5-10 | 200 | R-R | A+ | | Oklahoma State University | 152 |
| 390. | Larry Grayson | 2B | OAK | 17 | 7/28/1982 | 5-10 | 180 | R-R | AA | | Oviedo High School (Oviedo,FL) | 10 |
| 391. | Justin Knoedler | P | SF | 19 | 7/17/1980 | 6-2 | 205 | R-R | MLB | 2004-2006 | Lincoln Land Community College | 28 |
| 392. | Miguel Quintana | OF | BOS | 21 | 6/29/1979 | 6-1 | 195 | L-R | AA | | Florida International University | 81 |
| 393. | Omar Lopez | P | CIN | 18 | 2/10/1982 | 6-2 | 170 | B-R | Ind | | Blanca Malaret High School (Sabana Grande,PR) | |
| 396. | Jeff Haase | C | CLE | 22 | 5/15/1978 | 6-2 | 205 | R-R | A+ | | Cleveland State University | 17 |
| 398. | Mike Wombacher | 1B | NYY | 22 | 10/13/1977 | 6-5 | 235 | L-L | A | | Northeast Louisiana University | 29 |
| 399. | Pete Sikaras | P | ARI | 21 | 5/5/1979 | 6-2 | 210 | R-R | AAA | | University of Saint Francis (Ill.) | 1 |
| 400. | Jonathan Rogers | P | ATL | 18 | 7/2/1981 | 6-1 | 180 | R-R | Rookie | | Robert E Lee High School (Midland,TX) | 4 |