| 1 | 17 | June-Reg | Rick Asadoorian | OF | 18 | 6-2 | 185 | R | R | AAA | | Northbridge (Northbridge,MA) | $1,725,500 |
| 1 | 40 | June-Reg | Brad Baker | P | 18 | 6-2 | 195 | R | R | AAA | | Pioneer Valley Regional (Northfield,MA) | $844,000 |
| 1 | 48 | June-Reg | Casey Fossum | P | 21 | 6-1 | 160 | B | L | MLB | 2001-2009 | Texas A&M University | $680,000 |
| 2 | 76 | June-Reg | Matt Thompson | P | 17 | 6-1 | 205 | R | R | A+ | | Timberline (Boise,ID) | |
| 3 | 88 | June-Reg | Rich Rundles | P | 18 | 6-5 | 180 | L | L | MLB | 2008-2009 | Jefferson County (New Market,TN) | |
| 3 | 109 | June-Reg | Antron Seiber | OF | 19 | 6-1 | 185 | R | R | A+ | | Independence (Independence,LA) | |
| 4 | 139** | June-Reg | Rory Shortell | P | 18 | 6-3 | 205 | R | R | A+ | | Madison (Portland,OR) | |
| 5 | 169 | June-Reg | Greg Montalbano | P | 21 | 6-2 | 190 | L | L | AA | | Northeastern University | |
| 6 | 199 | June-Reg | Jon Henry Kail | OF | 18 | 6-1 | 199 | R | R | College | | Baldwin (Pittsburgh,PA) | |
| 7 | 229** | June-Reg | Rich Carroll | 1B | 19 | 6-3 | 220 | R | R | Rookie | | Venice (Venice,FL) | |
| 8 | 259 | June-Reg | Andy Heimbach | P | 21 | 6-2 | 185 | R | R | A | | Mount Vernon Nazarene University | |
| 9 | 289 | June-Reg | Richard Thoms | P | | | 0 | | | - | | Mississippi State University | |
| 10 | 319 | June-Reg | Brian Wiese | OF | 22 | 5-11 | 200 | R | R | A+ | | Mississippi State University | $3,000 |
| 11 | 349 | June-Reg | Kregg Jarvais | C | 22 | 6-2 | 215 | R | R | A | | University of Maine | |
| 12 | 379 | June-Reg | Lew Ford | CF | 22 | 6-0 | 190 | R | R | MLB | 2003-2007 | Dallas Baptist University | |
| 13 | 409 | June-Reg | Michael Dwyer | 1B | | | 0 | | | A+ | | University of Richmond | |
| 14 | 439 | June-Reg | B.J. Leach | P | 21 | 5-11 | 185 | R | R | AA | | Florida Southern College | |
| 15 | 469 | June-Reg | Brian Wiley | P | | | | | | College | | The Citadel | |
| 16 | 499** | June-Reg | Charlie Manning | P | 20 | 6-2 | 180 | L | L | MLB | 2008-2008 | Polk State College | |
| 17 | 529 | June-Reg | Trey Duncan | 3B | 18 | 6-0 | 220 | R | R | A | | Mississippi Gulf Coast Community College | |
| 18 | 559 | June-Reg | Jeff Waldron | C | 22 | 6-1 | 205 | L | R | AAA | | Boston College | |
| 19 | 589 | June-Reg | Jason Bottenfield | P | 22 | 6-2 | 210 | R | R | A | | University of Texas-Pan American | |
| 20 | 619 | June-Reg | Daniel Generelli | P | 18 | 6-2 | 200 | R | R | A | | Quinsigamond Community College | |
| 21 | 649** | June-Reg | Jason Henderson | P | | | 0 | | | - | | Bishop Hendricken (Warwick,RI) | |
| 22 | 679 | June-Reg | Ellis Debrow | 1B | | | 0 | | | - | | Woodham (Pensacola,FL) | |
| 23 | 709 | June-Reg | Nicolas Puckett | P | 18 | 6-0 | 200 | L | L | - | | Timberline (Boise,ID) | |
| 24 | 739** | June-Reg | Rex Rundgren | IF | 18 | 6-1 | 170 | R | R | AAA | | Mid-Pacific Institute (Honolulu,HI) | |
| 25 | 769 | June-Reg | Tim Mccabe | | 18 | 6-3 | 215 | R | R | Ind | | North Catholic (Pittsburgh,PA) | |
| 26 | 799** | June-Reg | Marshall McDougall | IF | 20 | 6-1 | 200 | R | R | MLB | 2005-2005 | Florida State University | |
| 27 | 829** | June-Reg | Mark Kiger | IF | 19 | 5-11 | 177 | R | R | AAA | | Grossmont College | |
| 28 | 859 | June-Reg | Jon Anderson | | 22 | 5-9 | 150 | B | R | A+ | | University of Illinois | |
| 29 | 889 | June-Reg | Barton Hollis | P | | | 0 | | | Ind | | Lawrence County (Moulton,AL) | |
| 30 | 919 | June-Reg | Charlie Frasier | | 19 | 6-2 | 220 | L | R | Ind | | Santa Rosa Junior College | |
| 31 | 949** | June-Reg | Jaime Bubela | OF | 21 | 6-1 | 200 | L | R | MLB | 2005-2005 | Baylor University | |
| 32 | 979 | June-Reg | David Flournoy | LF-RF | 17 | | 0 | | | - | | Deer Valley (Antioch,CA) | |
| 33 | 1009 | June-Reg | Perry Miley | CF | | | 0 | | | A- | | William Carey University | |
| 34 | 1039 | June-Reg | Dan Giese | P | 22 | 6-3 | 195 | R | R | MLB | 2007-2009 | University of San Diego | |
| 35 | 1069 | June-Reg | Ben Marbury | LF | | | 0 | | | Rookie | - | | |
| 36 | 1099 | June-Reg | John Brandon | | 19 | 5-11 | 180 | L | R | College | | Panola College | |
| 37 | 1129** | June-Reg | Chris Mabeus | P | 20 | 6-3 | 210 | R | R | MLB | 2006-2006 | Eastern Arizona College | |
| 38 | 1159 | June-Reg | Jesse Cooksey | P | | | 0 | | | - | | Port-Neches Groves (Port Neches,TX) | |
| 39 | 1189 | June-Reg | Matthew Ames | 1B | | | 0 | | | - | | Stanhope Elmore (Millbrook,AL) | |
| 40 | 1219 | June-Reg | Anthony Bass | LF | | | 0 | | | - | | Booker T. Washington (Tulsa,OK) | |
| 41 | 1248 | June-Reg | Justin Smetana | | 19 | 6-3 | 220 | L | L | Ind | | Cardinal (Middlefield,OH) | |
| 42 | 1276 | June-Reg | Bryan Rinehart | | | | | | | College | | Southington (Southington,CT) | |
| 43 | 1303** | June-Reg | Ryan Coffin | P | 17 | 6-4 | 180 | R | R | A+ | | Desert Vista (Phoenix,AZ) | |
| 44 | 1330 | June-Reg | Alan Lindsey | CF | 18 | 6-1 | 200 | R | R | College | | Lee-Davis (Mechanicsville,VA) | |
| 45 | 1355 | June-Reg | Brady Williams | IF | 19 | 6-1 | 180 | R | R | AA | | Pasco-Hernando Community College | |
| 46 | 1379 | June-Reg | Joe Kerrigan | P | 21 | 5-10 | 180 | L | R | A+ | | Temple University | |
| 47 | 1403 | June-Reg | James Burgess | | 18 | 6-3 | 202 | R | R | College | | Durango (Las Vegas,NV) | |
| 48 | 1427 | June-Reg | Joseph Kjose | P | 19 | 6-3 | 235 | R | R | Ind | | Cochise College | |
| 49 | 1450 | June-Reg | Jordan Remy | 2B | | | 0 | | | - | | Weston (Weston,MA) | |
| 50 | 1471** | June-Reg | Brian Buscher | 3B | 18 | 6-0 | 185 | L | R | MLB | 2007-2009 | Terry Parker (Jacksonville,FL) | |