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| 2010 | Topps | Regular Issue | 1 | Milwaukee Brewers | Prince Fielder profile |
| 2010 | Topps | Regular Issue | 2 | San Francisco Giants | Buster Posey c - Rookie Card profile |
| 2010 | Topps | Regular Issue | 3 | Chicago Cubs | Derrek Lee profile |
| 2010 | Topps | Regular Issue | 4 | No team | NL Batting Leaders Albert Pujols, Hanley Ramirez, Pablo Sandoval |
| 2010 | Topps | Regular Issue | 5 | Texas Rangers | Team Card |
| 2010 | Topps | Regular Issue | 6 | Chicago White Sox | Franchise History |
| 2010 | Topps | Regular Issue | 7 | New York Yankees | Mickey Mantle profile |
| 2010 | Topps | Regular Issue | 8 | No team | AL Batting Leaders Derek Jeter, Joe Mauer, Ichiro Suzuki |
| 2010 | Topps | Regular Issue | 9 | San Francisco Giants | Tim Lincecum p - NL Cy Young profile |
| 2010 | Topps | Regular Issue | 10 | Los Angeles Dodgers | Clayton Kershaw profile |
| 2010 | Topps | Regular Issue | 11 | Minnesota Twins | Orlando Cabrera profile |
| 2010 | Topps | Regular Issue | 12 | Arizona Diamondbacks | Doug Davis profile |
| 2010 | Topps | Regular Issue | 13 | Baltimore Orioles | Melvin Mora profile |
| 2010 | Topps | Regular Issue | 14 | Chicago Cubs | Ted Lilly profile |
| 2010 | Topps | Regular Issue | 15 | Los Angeles Angels | Bobby Abreu profile |
| 2010 | Topps | Regular Issue | 16 | Cincinnati Reds | Johnny Cueto profile |
| 2010 | Topps | Regular Issue | 17 | Colorado Rockies | Dexter Fowler profile |
| 2010 | Topps | Regular Issue | 18 | San Diego Padres | Tim Stauffer profile |
| 2010 | Topps | Regular Issue | 19 | Milwaukee Brewers | Felipe Lopez profile |
| 2010 | Topps | Regular Issue | 20 | Atlanta Braves | Tommy Hanson profile |
| 2010 | Topps | Regular Issue | 21 | Washington Nationals | Cristian Guzman profile |
| 2010 | Topps | Regular Issue | 22 | Minnesota Twins | Anthony Swarzak profile |
| 2010 | Topps | Regular Issue | 23 | Philadelphia Phillies | Shane Victorino profile |
| 2010 | Topps | Regular Issue | 24 | New York Mets | John Maine profile |
| 2010 | Topps | Regular Issue | 25 | Baltimore Orioles | Adam Jones profile |
| 2010 | Topps | Regular Issue | 26 | Pittsburgh Pirates | Zach Duke profile |
| 2010 | Topps | Regular Issue | 27 | Houston Astros | Photo day fun Lance Berkman, Mike Hampton |
| 2010 | Topps | Regular Issue | 28 | San Francisco Giants | Jonathan Sanchez profile |
| 2010 | Topps | Regular Issue | 29 | Detroit Tigers | Aubrey Huff profile |
| 2010 | Topps | Regular Issue | 30 | Boston Red Sox | Victor Martinez profile |
| 2010 | Topps | Regular Issue | 31 | Texas Rangers | Jason Grilli profile |
| 2010 | Topps | Regular Issue | 32 | Cincinnati Reds | Team Card |
| 2010 | Topps | Regular Issue | 33 | Seattle Mariners | Adam Moore profile |
| 2010 | Topps | Regular Issue | 34 | New York Yankees | Michael Dunn profile |
| 2010 | Topps | Regular Issue | 35 | Detroit Tigers | Rick Porcello profile |
| 2010 | Topps | Regular Issue | 36 | New York Mets | Tobi Stoner p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 37 | Atlanta Braves | Garret Anderson profile |
| 2010 | Topps | Regular Issue | 38 | Houston Astros | Team Card |
| 2010 | Topps | Regular Issue | 39 | Chicago Cubs | Jeff Baker profile |
| 2010 | Topps | Regular Issue | 40 | Florida Marlins | Josh Johnson profile |
| 2010 | Topps | Regular Issue | 41 | Los Angeles Dodgers | Franchise History |
| 2010 | Topps | Regular Issue | 42 | No team | Prince Fielder, Ryan Howard, Albert Pujols |
| 2010 | Topps | Regular Issue | 43 | Toronto Blue Jays | Marco Scutaro profile |
| 2010 | Topps | Regular Issue | 44 | Los Angeles Angels | Howie Kendrick profile |
| 2010 | Topps | Regular Issue | 45 | Baltimore Orioles | David Hernandez profile |
| 2010 | Topps | Regular Issue | 46 | Arizona Diamondbacks | Chad Tracy profile |
| 2010 | Topps | Regular Issue | 47 | San Francisco Giants | Brad Penny profile |
| 2010 | Topps | Regular Issue | 48 | Cincinnati Reds | Joey Votto profile |
| 2010 | Topps | Regular Issue | 49 | Colorado Rockies | Jorge De La Rosa profile |
| 2010 | Topps | Regular Issue | 50 | Kansas City Royals | Zack Greinke profile |
| 2010 | Topps | Regular Issue | 51 | Colorado Rockies | Eric Young of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 52 | Kansas City Royals | Billy Butler profile |
| 2010 | Topps | Regular Issue | 53 | Milwaukee Brewers | Craig Counsell profile |
| 2010 | Topps | Regular Issue | 54 | Los Angeles Angels | John Lackey profile |
| 2010 | Topps | Regular Issue | 55 | Los Angeles Dodgers | Manny Ramirez profile |
| 2010 | Topps | Regular Issue | 56 | New York Yankees | Andy Pettitte profile |
| 2010 | Topps | Regular Issue | 57 | New York Yankees | C.C. Sabathia profile |
| 2010 | Topps | Regular Issue | 58 | San Diego Padres | Kyle Blanks profile |
| 2010 | Topps | Regular Issue | 59 | Chicago Cubs | Kevin Gregg profile |
| 2010 | Topps | Regular Issue | 60 | New York Mets | David Wright profile |
| 2010 | Topps | Regular Issue | 61 | St. Louis Cardinals | Skip Schumaker profile |
| 2010 | Topps | Regular Issue | 62 | Texas Rangers | Kevin Millwood profile |
| 2010 | Topps | Regular Issue | 63 | Washington Nationals | Josh Bard profile |
| 2010 | Topps | Regular Issue | 64 | Cincinnati Reds | Drew Stubbs of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 65 | New York Yankees | Nick Swisher profile |
| 2010 | Topps | Regular Issue | 66 | Toronto Blue Jays | Kyle Phillips c - Rookie Card profile |
| 2010 | Topps | Regular Issue | 67 | Cleveland Indians | Matt LaPorta profile |
| 2010 | Topps | Regular Issue | 68 | Detroit Tigers | Brandon Inge profile |
| 2010 | Topps | Regular Issue | 69 | Kansas City Royals | Team Card |
| 2010 | Topps | Regular Issue | 70 | Philadelphia Phillies | Cole Hamels profile |
| 2010 | Topps | Regular Issue | 71 | Houston Astros | Mike Hampton profile |
| 2010 | Topps | Regular Issue | 72 | Milwaukee Brewers | Franchise History |
| 2010 | Topps | Regular Issue | 73 | No team | NL Wins Leaders Chris Carpenter, Jorge De La Rosa, Adam Wainwright |
| 2010 | Topps | Regular Issue | 74 | Los Angeles Dodgers | Casey Blake profile |
| 2010 | Topps | Regular Issue | 75 | San Diego Padres | Adrian Gonzalez profile |
| 2010 | Topps | Regular Issue | 76 | Los Angeles Angels | Joe Saunders profile |
| 2010 | Topps | Regular Issue | 77 | Atlanta Braves | Kenshin Kawakami profile |
| 2010 | Topps | Regular Issue | 78 | Baltimore Orioles | Cesar Izturis profile |
| 2010 | Topps | Regular Issue | 79 | Cincinnati Reds | Francisco Cordero profile |
| 2010 | Topps | Regular Issue | 80 | San Francisco Giants | Tim Lincecum profile |
| 2010 | Topps | Regular Issue | 81 | Chicago Cubs | Ryan Theriot profile |
| 2010 | Topps | Regular Issue | 82 | Colorado Rockies | Jason Marquis profile |
| 2010 | Topps | Regular Issue | 83 | Chicago White Sox | Mark Teahen profile |
| 2010 | Topps | Regular Issue | 84 | Detroit Tigers | Nate Robertson profile |
| 2010 | Topps | Regular Issue | 85 | Seattle Mariners | Ken Griffey dh profile |
| 2010 | Topps | Regular Issue | 86 | Kansas City Royals | Gil Meche profile |
| 2010 | Topps | Regular Issue | 87 | Houston Astros | Darin Erstad profile |
| 2010 | Topps | Regular Issue | 88 | New York Yankees | Jerry Hairston profile |
| 2010 | Topps | Regular Issue | 89 | Philadelphia Phillies | J.A. Happ Topps All-Star Rookie profile |
| 2010 | Topps | Regular Issue | 90 | Texas Rangers | Ian Kinsler profile |
| 2010 | Topps | Regular Issue | 91 | Seattle Mariners | Erik Bedard profile |
| 2010 | Topps | Regular Issue | 92 | San Diego Padres | David Eckstein profile |
| 2010 | Topps | Regular Issue | 93 | Minnesota Twins | Joe Nathan profile |
| 2010 | Topps | Regular Issue | 94 | Texas Rangers | Ivan Rodriguez profile |
| 2010 | Topps | Regular Issue | 95 | Tampa Bay Rays | Carl Crawford profile |
| 2010 | Topps | Regular Issue | 96 | Los Angeles Dodgers | Jon Garland profile |
| 2010 | Topps | Regular Issue | 97 | San Diego Padres | Luis Durango 2b - Rookie Card profile |
| 2010 | Topps | Regular Issue | 98 | San Diego Padres | Cesar Ramos p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 99 | Pittsburgh Pirates | Garrett Jones profile |
| 2010 | Topps | Regular Issue | 100 | St. Louis Cardinals | Albert Pujols profile |
| 2010 | Topps | Regular Issue | 101 | Minnesota Twins | Scott Baker profile |
| 2010 | Topps | Regular Issue | 102 | Minnesota Twins | Team Card |
| 2010 | Topps | Regular Issue | 103 | New York Mets | Daniel Murphy profile |
| 2010 | Topps | Regular Issue | 104 | New York Mets | Franchise History |
| 2010 | Topps | Regular Issue | 105 | San Francisco Giants | Madison Bumgarner p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 106 | No team | NL ERA Leaders Chris Carpenter, Jair Jurrjens, Tim Lincecum |
| 2010 | Topps | Regular Issue | 107 | Oakland Athletics | Scott Hairston profile |
| 2010 | Topps | Regular Issue | 108 | Los Angeles Angels | Erick Aybar profile |
| 2010 | Topps | Regular Issue | 109 | Cleveland Indians | Justin Masterson profile |
| 2010 | Topps | Regular Issue | 110 | Pittsburgh Pirates | Andrew McCutchen Topps All-Star Rookie profile |
| 2010 | Topps | Regular Issue | 111 | Baltimore Orioles | Ty Wigginton profile |
| 2010 | Topps | Regular Issue | 112 | San Diego Padres | Kevin Correia profile |
| 2010 | Topps | Regular Issue | 113 | Cincinnati Reds | Willy Taveras profile |
| 2010 | Topps | Regular Issue | 114 | Colorado Rockies | Chris Iannetta profile |
| 2010 | Topps | Regular Issue | 115 | Chicago White Sox | Gordon Beckham Topps All-Star Rookie profile |
| 2010 | Topps | Regular Issue | 116 | Milwaukee Brewers | Carlos Gomez profile |
| 2010 | Topps | Regular Issue | 117 | Kansas City Royals | David DeJesus profile |
| 2010 | Topps | Regular Issue | 118 | Seattle Mariners | Brandon Morrow profile |
| 2010 | Topps | Regular Issue | 119 | Detroit Tigers | Wilkin Ramirez profile |
| 2010 | Topps | Regular Issue | 120 | New York Yankees | Jorge Posada profile |
| 2010 | Topps | Regular Issue | 121 | Oakland Athletics | Brett Anderson profile |
| 2010 | Topps | Regular Issue | 122 | Philadelphia Phillies | Carlos Ruiz profile |
| 2010 | Topps | Regular Issue | 123 | Chicago Cubs | Jeff Samardzija profile |
| 2010 | Topps | Regular Issue | 124 | Milwaukee Brewers | Rickie Weeks profile |
| 2010 | Topps | Regular Issue | 125 | Seattle Mariners | Ichiro Suzuki profile |
| 2010 | Topps | Regular Issue | 126 | St. Louis Cardinals | John Smoltz profile |
| 2010 | Topps | Regular Issue | 127 | Texas Rangers | Hank Blalock profile |
| 2010 | Topps | Regular Issue | 128 | Washington Nationals | Garrett Mock profile |
| 2010 | Topps | Regular Issue | 129 | Atlanta Braves | Reid Gorecki of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 130 | Los Angeles Angels | Vladimir Guerrero profile |
| 2010 | Topps | Regular Issue | 131 | Boston Red Sox | Dustin Richardson p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 132 | Philadelphia Phillies | Cliff Lee profile |
| 2010 | Topps | Regular Issue | 133 | San Francisco Giants | Freddy Sanchez profile |
| 2010 | Topps | Regular Issue | 134 | Philadelphia Phillies | Team Card Ryan Howard, Jimmy Rollins, Chase Utley |
| 2010 | Topps | Regular Issue | 135 | Chicago Cubs | Ryan Dempster profile |
| 2010 | Topps | Regular Issue | 136 | St. Louis Cardinals | Adam Wainwright profile |
| 2010 | Topps | Regular Issue | 137 | Oakland Athletics | Rickey Henderson Franchise History profile |
| 2010 | Topps | Regular Issue | 138 | No team | AL Home Run Leaders Jason Bay, Carlos Pena, Mark Teixeira |
| 2010 | Topps | Regular Issue | 139 | Texas Rangers | Frank Francisco profile |
| 2010 | Topps | Regular Issue | 140 | St. Louis Cardinals | Matt Holliday profile |
| 2010 | Topps | Regular Issue | 141 | Los Angeles Angels | Chone Figgins profile |
| 2010 | Topps | Regular Issue | 142 | Atlanta Braves | Tim Hudson profile |
| 2010 | Topps | Regular Issue | 143 | Texas Rangers | Omar Vizquel profile |
| 2010 | Topps | Regular Issue | 144 | Chicago Cubs | Rich Harden profile |
| 2010 | Topps | Regular Issue | 145 | Arizona Diamondbacks | Justin Upton profile |
| 2010 | Topps | Regular Issue | 146 | Atlanta Braves | Yunel Escobar profile |
| 2010 | Topps | Regular Issue | 147 | Colorado Rockies | Huston Street profile |
| 2010 | Topps | Regular Issue | 148 | Florida Marlins | Cody Ross profile |
| 2010 | Topps | Regular Issue | 149 | Kansas City Royals | Jose Guillen profile |
| 2010 | Topps | Regular Issue | 150 | Minnesota Twins | Joe Mauer profile |
| 2010 | Topps | Regular Issue | 151 | Milwaukee Brewers | Mat Gamel profile |
| 2010 | Topps | Regular Issue | 152 | Washington Nationals | Nyjer Morgan profile |
| 2010 | Topps | Regular Issue | 153 | Oakland Athletics | Justin Duchscherer profile |
| 2010 | Topps | Regular Issue | 154 | Philadelphia Phillies | Pedro Feliz profile |
| 2010 | Topps | Regular Issue | 155 | Kansas City Royals | Zack Greinke p - AL Cy Young Winner profile |
| 2010 | Topps | Regular Issue | 156 | San Diego Padres | Tony Gwynn profile |
| 2010 | Topps | Regular Issue | 157 | Seattle Mariners | Mike Sweeney dh profile |
| 2010 | Topps | Regular Issue | 158 | Tampa Bay Rays | Jeff Niemann profile |
| 2010 | Topps | Regular Issue | 159 | Toronto Blue Jays | Vernon Wells profile |
| 2010 | Topps | Regular Issue | 160 | Houston Astros | Miguel Tejada profile |
| 2010 | Topps | Regular Issue | 161 | Minnesota Twins | Denard Span profile |
| 2010 | Topps | Regular Issue | 162 | Tampa Bay Rays | Wade Davis p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 163 | Milwaukee Brewers | Josh Butler p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 164 | Cleveland Indians | Carlos Carrasco p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 165 | Cincinnati Reds | Brandon Phillips profile |
| 2010 | Topps | Regular Issue | 166 | Arizona Diamondbacks | Eric Byrnes profile |
| 2010 | Topps | Regular Issue | 167 | San Diego Padres | Team Card |
| 2010 | Topps | Regular Issue | 168 | Oakland Athletics | Brad Kilby p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 169 | Pittsburgh Pirates | Franchise History |
| 2010 | Topps | Regular Issue | 170 | Boston Red Sox | Jason Bay profile |
| 2010 | Topps | Regular Issue | 171 | No team | AL Wins Leaders Felix Hernandez, C.C. Sabathia, Justin Verlander |
| 2010 | Topps | Regular Issue | 172 | Minnesota Twins | Joe Mauer c - Award Winner - AL MVP profile |
| 2010 | Topps | Regular Issue | 173 | Los Angeles Angels | Kendrys Morales profile |
| 2010 | Topps | Regular Issue | 174 | Atlanta Braves | Mike Gonzalez profile |
| 2010 | Topps | Regular Issue | 175 | Texas Rangers | Josh Hamilton profile |
| 2010 | Topps | Regular Issue | 176 | Milwaukee Brewers | Yovani Gallardo profile |
| 2010 | Topps | Regular Issue | 177 | Toronto Blue Jays | Adam Lind profile |
| 2010 | Topps | Regular Issue | 178 | Cleveland Indians | Kerry Wood profile |
| 2010 | Topps | Regular Issue | 179 | Colorado Rockies | Ryan Spilborghs profile |
| 2010 | Topps | Regular Issue | 180 | Chicago White Sox | Jayson Nix profile |
| 2010 | Topps | Regular Issue | 181 | Florida Marlins | Nick Johnson profile |
| 2010 | Topps | Regular Issue | 182 | Kansas City Royals | Coco Crisp profile |
| 2010 | Topps | Regular Issue | 183 | Boston Red Sox | Jonathan Papelbon profile |
| 2010 | Topps | Regular Issue | 184 | New York Mets | Jeff Francoeur profile |
| 2010 | Topps | Regular Issue | 185 | New York Yankees | Hideki Matsui dh profile |
| 2010 | Topps | Regular Issue | 186 | Oakland Athletics | Andrew Bailey profile |
| 2010 | Topps | Regular Issue | 187 | San Diego Padres | Will Venable profile |
| 2010 | Topps | Regular Issue | 188 | Philadelphia Phillies | Joe Blanton profile |
| 2010 | Topps | Regular Issue | 189 | Seattle Mariners | Adrian Beltre profile |
| 2010 | Topps | Regular Issue | 190 | San Francisco Giants | Pablo Sandoval profile |
| 2010 | Topps | Regular Issue | 191 | San Diego Padres | Mat Latos profile |
| 2010 | Topps | Regular Issue | 192 | Texas Rangers | Andruw Jones dh profile |
| 2010 | Topps | Regular Issue | 193 | Washington Nationals | Shairon Martis profile |
| 2010 | Topps | Regular Issue | 194 | Pittsburgh Pirates | Neil Walker 3b - Rookie Card profile |
| 2010 | Topps | Regular Issue | 195 | Tampa Bay Rays | James Shields profile |
| 2010 | Topps | Regular Issue | 196 | Washington Nationals | Ian Desmond ss - Rookie Card profile |
| 2010 | Topps | Regular Issue | 197 | Cleveland Indians | Team Card |
| 2010 | Topps | Regular Issue | 198 | Florida Marlins | Franchise History |
| 2010 | Topps | Regular Issue | 199 | Seattle Mariners | Ichiro Suzuki Team Card profile |
| 2010 | Topps | Regular Issue | 200 | Toronto Blue Jays | Roy Halladay profile |
| 2010 | Topps | Regular Issue | 201 | Detroit Tigers | Team Card |
| 2010 | Topps | Regular Issue | 202 | San Francisco Giants | Franchise History |
| 2010 | Topps | Regular Issue | 203 | No team | AL ERA Leaders Zack Greinke, Roy Halladay, Felix Hernandez |
| 2010 | Topps | Regular Issue | 204 | Texas Rangers | Turning Two for Texas Elvis Andrus, Ian Kinsler |
| 2010 | Topps | Regular Issue | 205 | Florida Marlins | Chris Coghlan Topps All-Star Rookie profile |
| 2010 | Topps | Regular Issue | 206 | No team | NL Home Run Leaders Prince Fielder, Ryan Howard, Albert Pujols |
| 2010 | Topps | Regular Issue | 207 | St. Louis Cardinals | Colby Rasmus profile |
| 2010 | Topps | Regular Issue | 208 | Boston Red Sox | Tim Wakefield profile |
| 2010 | Topps | Regular Issue | 209 | Chicago White Sox | Alexei Ramirez profile |
| 2010 | Topps | Regular Issue | 210 | Boston Red Sox | Josh Beckett profile |
| 2010 | Topps | Regular Issue | 211 | Atlanta Braves | Kelly Shoppach profile |
| 2010 | Topps | Regular Issue | 212 | Detroit Tigers | Magglio Ordonez profile |
| 2010 | Topps | Regular Issue | 213 | Florida Marlins | Ricky Nolasco profile |
| 2010 | Topps | Regular Issue | 214 | Los Angeles Dodgers | Matt Kemp profile |
| 2010 | Topps | Regular Issue | 215 | Arizona Diamondbacks | Max Scherzer profile |
| 2010 | Topps | Regular Issue | 216 | Milwaukee Brewers | Mike Cameron profile |
| 2010 | Topps | Regular Issue | 217 | Oakland Athletics | Gio Gonzalez profile |
| 2010 | Topps | Regular Issue | 218 | New York Mets | Fernando Martinez profile |
| 2010 | Topps | Regular Issue | 219 | Pittsburgh Pirates | Kevin Hart profile |
| 2010 | Topps | Regular Issue | 220 | San Francisco Giants | Randy Johnson profile |
| 2010 | Topps | Regular Issue | 221 | Seattle Mariners | Russell Branyan profile |
| 2010 | Topps | Regular Issue | 222 | Detroit Tigers | Curtis Granderson profile |
| 2010 | Topps | Regular Issue | 223 | Atlanta Braves | Ryan Church profile |
| 2010 | Topps | Regular Issue | 224 | Toronto Blue Jays | Rod Barajas profile |
| 2010 | Topps | Regular Issue | 225 | Tampa Bay Rays | David Price profile |
| 2010 | Topps | Regular Issue | 226 | Los Angeles Angels | Juan Rivera profile |
| 2010 | Topps | Regular Issue | 227 | New York Mets | Josh Thole c - Rookie Card profile |
| 2010 | Topps | Regular Issue | 228 | Los Angeles Angels | Chris Pettit of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 229 | Pittsburgh Pirates | Daniel McCutchen p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 230 | Los Angeles Dodgers | Jonathan Broxton profile |
| 2010 | Topps | Regular Issue | 231 | Baltimore Orioles | Luke Scott dh profile |
| 2010 | Topps | Regular Issue | 232 | St. Louis Cardinals | Team Card |
| 2010 | Topps | Regular Issue | 233 | No team | AL RBI Leaders Jason Bay, Adam Lind, Mark Teixeira |
| 2010 | Topps | Regular Issue | 234 | Tampa Bay Rays | Franchise History |
| 2010 | Topps | Regular Issue | 235 | Texas Rangers | Neftali Feliz profile |
| 2010 | Topps | Regular Issue | 236 | Oakland Athletics | Andrew Bailey p - AL Rookie of the Year profile |
| 2010 | Topps | Regular Issue | 237 | Milwaukee Brewers | Brew Crew Knockout Ryan Braun, Cecil Fielder |
| 2010 | Topps | Regular Issue | 238 | Colorado Rockies | Ian Stewart profile |
| 2010 | Topps | Regular Issue | 239 | San Francisco Giants | Juan Uribe profile |
| 2010 | Topps | Regular Issue | 240 | Toronto Blue Jays | Ricky Romero profile |
| 2010 | Topps | Regular Issue | 241 | Boston Red Sox | Rocco Baldelli profile |
| 2010 | Topps | Regular Issue | 242 | Chicago White Sox | Bobby Jenks profile |
| 2010 | Topps | Regular Issue | 243 | Cleveland Indians | Asdrubal Cabrera profile |
| 2010 | Topps | Regular Issue | 244 | San Francisco Giants | Barry Zito profile |
| 2010 | Topps | Regular Issue | 245 | Houston Astros | Lance Berkman profile |
| 2010 | Topps | Regular Issue | 246 | Florida Marlins | Juan Carlos Oviedo profile |
| 2010 | Topps | Regular Issue | 247 | Los Angeles Dodgers | Andre Ethier profile |
| 2010 | Topps | Regular Issue | 248 | Milwaukee Brewers | Jason Kendall profile |
| 2010 | Topps | Regular Issue | 249 | New York Mets | Jon Niese profile |
| 2010 | Topps | Regular Issue | 250 | New York Yankees | Mark Teixeira profile |
| 2010 | Topps | Regular Issue | 251 | Washington Nationals | John Lannan profile |
| 2010 | Topps | Regular Issue | 252 | Pittsburgh Pirates | Ronny Cedeno profile |
| 2010 | Topps | Regular Issue | 253 | San Francisco Giants | Bengie Molina profile |
| 2010 | Topps | Regular Issue | 254 | Detroit Tigers | Edwin Jackson profile |
| 2010 | Topps | Regular Issue | 255 | Texas Rangers | Chris Davis profile |
| 2010 | Topps | Regular Issue | 256 | Pittsburgh Pirates | Akinori Iwamura profile |
| 2010 | Topps | Regular Issue | 257 | Oakland Athletics | Bobby Crosby profile |
| 2010 | Topps | Regular Issue | 258 | Toronto Blue Jays | Edwin Encarnacion profile |
| 2010 | Topps | Regular Issue | 259 | Chicago White Sox | Daniel Hudson p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 260 | New York Yankees | Franchise History |
| 2010 | Topps | Regular Issue | 261 | Oakland Athletics | Matt Carson of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 262 | Cincinnati Reds | Homer Bailey profile |
| 2010 | Topps | Regular Issue | 263 | Detroit Tigers | Placido Polanco profile |
| 2010 | Topps | Regular Issue | 264 | Arizona Diamondbacks | Franchise History Randy Johnson, Curt Schilling |
| 2010 | Topps | Regular Issue | 265 | Los Angeles Angels | Team Card |
| 2010 | Topps | Regular Issue | 266 | Houston Astros | Humberto Quintero profile |
| 2010 | Topps | Regular Issue | 267 | Toronto Blue Jays | Cito Gaston Franchise History profile |
| 2010 | Topps | Regular Issue | 268 | Los Angeles Dodgers | Juan Pierre profile |
| 2010 | Topps | Regular Issue | 269 | New York Yankees | Anthem in the Bronx Robinson Cano, Derek Jeter, Alex Rodriguez |
| 2010 | Topps | Regular Issue | 270 | Cleveland Indians | Michael Brantley of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 271 | Chicago White Sox | Jermaine Dye profile |
| 2010 | Topps | Regular Issue | 272 | Atlanta Braves | Jair Jurrjens profile |
| 2010 | Topps | Regular Issue | 273 | Minnesota Twins | Pat Neshek profile |
| 2010 | Topps | Regular Issue | 274 | Arizona Diamondbacks | Stephen Drew profile |
| 2010 | Topps | Regular Issue | 275 | Florida Marlins | Chris Coghlan of - NL Rookie of the Year profile |
| 2010 | Topps | Regular Issue | 276 | Florida Marlins | Matt Lindstrom profile |
| 2010 | Topps | Regular Issue | 277 | Detroit Tigers | Jarrod Washburn profile |
| 2010 | Topps | Regular Issue | 278 | New York Mets | Carlos Delgado profile |
| 2010 | Topps | Regular Issue | 279 | Los Angeles Dodgers | Randy Wolf profile |
| 2010 | Topps | Regular Issue | 280 | St. Louis Cardinals | Mark DeRosa profile |
| 2010 | Topps | Regular Issue | 281 | Milwaukee Brewers | Braden Looper profile |
| 2010 | Topps | Regular Issue | 282 | Washington Nationals | Franchise History |
| 2010 | Topps | Regular Issue | 283 | Oakland Athletics | Adam Kennedy profile |
| 2010 | Topps | Regular Issue | 284 | Pittsburgh Pirates | Ross Ohlendorf profile |
| 2010 | Topps | Regular Issue | 285 | Oakland Athletics | Kurt Suzuki profile |
| 2010 | Topps | Regular Issue | 286 | Atlanta Braves | Javier Vazquez profile |
| 2010 | Topps | Regular Issue | 287 | Cleveland Indians | Jhonny Peralta profile |
| 2010 | Topps | Regular Issue | 288 | Boston Red Sox | Franchise History |
| 2010 | Topps | Regular Issue | 289 | Toronto Blue Jays | Lyle Overbay profile |
| 2010 | Topps | Regular Issue | 290 | Los Angeles Dodgers | Orlando Hudson profile |
| 2010 | Topps | Regular Issue | 291 | Washington Nationals | Austin Kearns profile |
| 2010 | Topps | Regular Issue | 292 | Houston Astros | Tommy Manzella ss - Rookie Card profile |
| 2010 | Topps | Regular Issue | 293 | Detroit Tigers | Brent Dlugach ss - Rookie Card profile |
| 2010 | Topps | Regular Issue | 294 | Washington Nationals | Adam Dunn profile |
| 2010 | Topps | Regular Issue | 295 | Boston Red Sox | Kevin Youkilis profile |
| 2010 | Topps | Regular Issue | 296 | Atlanta Braves | Team Card |
| 2010 | Topps | Regular Issue | 297 | Tampa Bay Rays | Ben Zobrist profile |
| 2010 | Topps | Regular Issue | 298 | Baltimore Orioles | Team Card |
| 2010 | Topps | Regular Issue | 299 | New York Mets | Gary Sheffield profile |
| 2010 | Topps | Regular Issue | 300 | Philadelphia Phillies | Chase Utley profile |
| 2010 | Topps | Regular Issue | 301 | Oakland Athletics | Jack Cust dh profile |
| 2010 | Topps | Regular Issue | 302 | Boston Red Sox | Classic Combo David Ortiz, Kevin Youkilis |
| 2010 | Topps | Regular Issue | 303 | Arizona Diamondbacks | Christopher Snyder profile |
| 2010 | Topps | Regular Issue | 304 | Atlanta Braves | Adam LaRoche profile |
| 2010 | Topps | Regular Issue | 305 | Cincinnati Reds | Juan Francisco 3b - Rookie Card profile |
| 2010 | Topps | Regular Issue | 306 | Chicago Cubs | Milton Bradley profile |
| 2010 | Topps | Regular Issue | 307 | Oakland Athletics | Henry Rodriguez p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 308 | Pittsburgh Pirates | Robinzon Diaz profile |
| 2010 | Topps | Regular Issue | 309 | Detroit Tigers | Gerald Laird profile |
| 2010 | Topps | Regular Issue | 310 | Texas Rangers | Elvis Andrus Topps All-Star Rookie profile |
| 2010 | Topps | Regular Issue | 311 | Houston Astros | Jose Valverde profile |
| 2010 | Topps | Regular Issue | 312 | Chicago White Sox | Tyler Flowers c - Rookie Card profile |
| 2010 | Topps | Regular Issue | 313 | Minnesota Twins | Jason Kubel dh profile |
| 2010 | Topps | Regular Issue | 314 | New York Mets | Angel Pagan profile |
| 2010 | Topps | Regular Issue | 315 | Los Angeles Angels | Scott Kazmir profile |
| 2010 | Topps | Regular Issue | 316 | Arizona Diamondbacks | Chris Young profile |
| 2010 | Topps | Regular Issue | 317 | Pittsburgh Pirates | Ryan Doumit profile |
| 2010 | Topps | Regular Issue | 318 | San Francisco Giants | Nate Schierholtz profile |
| 2010 | Topps | Regular Issue | 319 | St. Louis Cardinals | Ryan Franklin profile |
| 2010 | Topps | Regular Issue | 320 | Atlanta Braves | Brian McCann profile |
| 2010 | Topps | Regular Issue | 321 | Tampa Bay Rays | Pat Burrell profile |
| 2010 | Topps | Regular Issue | 322 | Oakland Athletics | Travis Buck profile |
| 2010 | Topps | Regular Issue | 323 | St. Louis Cardinals | Cris Carpenter profile |
| 2010 | Topps | Regular Issue | 324 | Chicago White Sox | Alex Rios profile |
| 2010 | Topps | Regular Issue | 325 | St. Louis Cardinals | Julio Lugo profile |
| 2010 | Topps | Regular Issue | 326 | Chicago Cubs | Tyler Colvin of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 327 | St. Louis Cardinals | Albert Pujols Award Winner - NL MVP profile |
| 2010 | Topps | Regular Issue | 328 | Chicago Cubs | Team Card |
| 2010 | Topps | Regular Issue | 329 | Colorado Rockies | Franchise History |
| 2010 | Topps | Regular Issue | 330 | Arizona Diamondbacks | Brandon Allen of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 331 | Milwaukee Brewers | Ryan Braun profile |
| 2010 | Topps | Regular Issue | 332 | Colorado Rockies | Brad Hawpe profile |
| 2010 | Topps | Regular Issue | 333 | St. Louis Cardinals | Ryan Ludwick profile |
| 2010 | Topps | Regular Issue | 334 | Philadelphia Phillies | Jayson Werth profile |
| 2010 | Topps | Regular Issue | 335 | Arizona Diamondbacks | Jordan Norberto p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 336 | Texas Rangers | C.J. Wilson profile |
| 2010 | Topps | Regular Issue | 337 | Chicago Cubs | Carlos Zambrano profile |
| 2010 | Topps | Regular Issue | 338 | Toronto Blue Jays | Brett Cecil profile |
| 2010 | Topps | Regular Issue | 339 | New York Mets | Jose Reyes profile |
| 2010 | Topps | Regular Issue | 340 | Toronto Blue Jays | John Buck profile |
| 2010 | Topps | Regular Issue | 341 | Texas Rangers | Nolan Ryan Franchise History profile |
| 2010 | Topps | Regular Issue | 342 | Atlanta Braves | Melky Cabrera profile |
| 2010 | Topps | Regular Issue | 343 | Washington Nationals | Brian Bruney profile |
| 2010 | Topps | Regular Issue | 344 | Houston Astros | Brett Myers profile |
| 2010 | Topps | Regular Issue | 345 | Florida Marlins | Chris Volstad profile |
| 2010 | Topps | Regular Issue | 346 | Texas Rangers | Taylor Teagarden profile |
| 2010 | Topps | Regular Issue | 347 | Cincinnati Reds | Aaron Harang profile |
| 2010 | Topps | Regular Issue | 348 | Washington Nationals | Jordan Zimmermann profile |
| 2010 | Topps | Regular Issue | 349 | Baltimore Orioles | Felix Pie profile |
| 2010 | Topps | Regular Issue | 350 | Milwaukee Brewers | Classic combo Ryan Braun, Prince Fielder |
| 2010 | Topps | Regular Issue | 351 | Baltimore Orioles | Koji Uehara profile |
| 2010 | Topps | Regular Issue | 352 | Florida Marlins | Cameron Maybin profile |
| 2010 | Topps | Regular Issue | 353 | Atlanta Braves | Jason Heyward of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 354 | Tampa Bay Rays | Evan Longoria profile |
| 2010 | Topps | Regular Issue | 355 | Chicago Cubs | James Russell p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 356 | Los Angeles Angels | Mike Scioscia Franchise History profile |
| 2010 | Topps | Regular Issue | 357 | Toronto Blue Jays | Scott Downs profile |
| 2010 | Topps | Regular Issue | 358 | Chicago White Sox | Mark Buehrle profile |
| 2010 | Topps | Regular Issue | 359 | Chicago Cubs | Aramis Ramirez profile |
| 2010 | Topps | Regular Issue | 360 | Minnesota Twins | Justin Morneau profile |
| 2010 | Topps | Regular Issue | 361 | Washington Nationals | Team Card |
| 2010 | Topps | Regular Issue | 362 | Toronto Blue Jays | Travis Snider profile |
| 2010 | Topps | Regular Issue | 363 | New York Yankees | Joba Chamberlain profile |
| 2010 | Topps | Regular Issue | 364 | Milwaukee Brewers | Trevor Hoffman profile |
| 2010 | Topps | Regular Issue | 365 | Cincinnati Reds | Logan Ondrusek p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 366 | Los Angeles Dodgers | Hiroki Kuroda profile |
| 2010 | Topps | Regular Issue | 367 | Houston Astros | Wandy Rodriguez profile |
| 2010 | Topps | Regular Issue | 368 | Los Angeles Dodgers | Wade LeBlanc profile |
| 2010 | Topps | Regular Issue | 369 | Boston Red Sox | David Ortiz dh profile |
| 2010 | Topps | Regular Issue | 370 | New York Yankees | Robinson Cano profile |
| 2010 | Topps | Regular Issue | 371 | San Diego Padres | Nick Hundley profile |
| 2010 | Topps | Regular Issue | 372 | Philadelphia Phillies | Franchise History |
| 2010 | Topps | Regular Issue | 373 | Colorado Rockies | Clint Barmes profile |
| 2010 | Topps | Regular Issue | 374 | Texas Rangers | Scott Feldman profile |
| 2010 | Topps | Regular Issue | 375 | Washington Nationals | Jesus Flores profile |
| 2010 | Topps | Regular Issue | 376 | Colorado Rockies | Esmil Rogers p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 377 | Seattle Mariners | Felix Hernandez profile |
| 2010 | Topps | Regular Issue | 378 | Los Angeles Dodgers | George Sherrill profile |
| 2010 | Topps | Regular Issue | 379 | New York Yankees | Philip Hughes profile |
| 2010 | Topps | Regular Issue | 380 | Boston Red Sox | J.D. Drew profile |
| 2010 | Topps | Regular Issue | 381 | Arizona Diamondbacks | Miguel Montero checklist profile |
| 2010 | Topps | Regular Issue | 382 | Kansas City Royals | Kyle Davies profile |
| 2010 | Topps | Regular Issue | 383 | Atlanta Braves | Derek Lowe profile |
| 2010 | Topps | Regular Issue | 384 | Houston Astros | Chris Johnson 3b - Rookie Card profile |
| 2010 | Topps | Regular Issue | 385 | Los Angeles Angels | Torii Hunter profile |
| 2010 | Topps | Regular Issue | 386 | Arizona Diamondbacks | Dan Haren profile |
| 2010 | Topps | Regular Issue | 387 | Kansas City Royals | Josh Fields profile |
| 2010 | Topps | Regular Issue | 388 | Los Angeles Angels | Joel Pineiro profile |
| 2010 | Topps | Regular Issue | 389 | Colorado Rockies | Troy Tulowitzki profile |
| 2010 | Topps | Regular Issue | 390 | Los Angeles Angels | Ervin Santana profile |
| 2010 | Topps | Regular Issue | 391 | Milwaukee Brewers | Manny Parra profile |
| 2010 | Topps | Regular Issue | 392 | Los Angeles Dodgers | Carlos Monasterios p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 393 | Toronto Blue Jays | Jason Frasor profile |
| 2010 | Topps | Regular Issue | 394 | New York Mets | Luis Castillo profile |
| 2010 | Topps | Regular Issue | 395 | New York Mets | Jenrry Mejia p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 396 | Cleveland Indians | Jake Westbrook profile |
| 2010 | Topps | Regular Issue | 397 | Colorado Rockies | Team Card |
| 2010 | Topps | Regular Issue | 398 | Colorado Rockies | Carlos Gonzalez profile |
| 2010 | Topps | Regular Issue | 399 | Tampa Bay Rays | Matt Garza profile |
| 2010 | Topps | Regular Issue | 400 | New York Yankees | Alex Rodriguez profile |
| 2010 | Topps | Regular Issue | 401 | Los Angeles Dodgers | Chad Billingsley profile |
| 2010 | Topps | Regular Issue | 402 | Tampa Bay Rays | J.P. Howell profile |
| 2010 | Topps | Regular Issue | 403 | Philadelphia Phillies | Jimmy Rollins profile |
| 2010 | Topps | Regular Issue | 404 | New York Yankees | Mariano Rivera profile |
| 2010 | Topps | Regular Issue | 405 | Toronto Blue Jays | Dustin McGowan profile |
| 2010 | Topps | Regular Issue | 406 | Colorado Rockies | Jeff Francis profile |
| 2010 | Topps | Regular Issue | 407 | Minnesota Twins | Nick Punto profile |
| 2010 | Topps | Regular Issue | 408 | Detroit Tigers | Franchise History |
| 2010 | Topps | Regular Issue | 409 | Chicago Cubs | Kosuke Fukudome profile |
| 2010 | Topps | Regular Issue | 410 | Oakland Athletics | Team Card |
| 2010 | Topps | Regular Issue | 411 | Seattle Mariners | Jack Wilson profile |
| 2010 | Topps | Regular Issue | 412 | San Francisco Giants | Team Card |
| 2010 | Topps | Regular Issue | 413 | Minnesota Twins | J.J. Hardy profile |
| 2010 | Topps | Regular Issue | 414 | Florida Marlins | Sean West profile |
| 2010 | Topps | Regular Issue | 415 | Cincinnati Reds | Franchise History Johnny Bench, Tony Perez |
| 2010 | Topps | Regular Issue | 416 | New York Mets | Ruben Tejada ss - Rookie Card profile |
| 2010 | Topps | Regular Issue | 417 | Oakland Athletics | Dallas Braden profile |
| 2010 | Topps | Regular Issue | 418 | Cleveland Indians | Aaron Laffey profile |
| 2010 | Topps | Regular Issue | 419 | Seattle Mariners | David Aardsma profile |
| 2010 | Topps | Regular Issue | 420 | Cleveland Indians | Shin-Soo Choo profile |
| 2010 | Topps | Regular Issue | 421 | Seattle Mariners | Doug Fister profile |
| 2010 | Topps | Regular Issue | 422 | Oakland Athletics | Vincent Mazzaro profile |
| 2010 | Topps | Regular Issue | 423 | Baltimore Orioles | Brad Bergesen profile |
| 2010 | Topps | Regular Issue | 424 | Philadelphia Phillies | David Herndon p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 425 | Detroit Tigers | Dontrelle Willis profile |
| 2010 | Topps | Regular Issue | 426 | Arizona Diamondbacks | Mark Reynolds profile |
| 2010 | Topps | Regular Issue | 427 | Arizona Diamondbacks | Brandon Webb profile |
| 2010 | Topps | Regular Issue | 428 | Baltimore Orioles | Cal Ripken Franchise History profile |
| 2010 | Topps | Regular Issue | 429 | Colorado Rockies | Seth Smith profile |
| 2010 | Topps | Regular Issue | 430 | Houston Astros | Kazuo Matsui profile |
| 2010 | Topps | Regular Issue | 431 | Pittsburgh Pirates | John Raynor of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 432 | New York Yankees | A.J. Burnett profile |
| 2010 | Topps | Regular Issue | 433 | Texas Rangers | Julio Borbon profile |
| 2010 | Topps | Regular Issue | 434 | Minnesota Twins | Kevin Slowey profile |
| 2010 | Topps | Regular Issue | 435 | Texas Rangers | Nelson Cruz profile |
| 2010 | Topps | Regular Issue | 436 | New York Mets | Team Card |
| 2010 | Topps | Regular Issue | 437 | Kansas City Royals | Luke Hochevar profile |
| 2010 | Topps | Regular Issue | 438 | Tampa Bay Rays | Jason Bartlett profile |
| 2010 | Topps | Regular Issue | 439 | Florida Marlins | Emilio Bonifacio profile |
| 2010 | Topps | Regular Issue | 440 | Washington Nationals | Willie Harris profile |
| 2010 | Topps | Regular Issue | 441 | Detroit Tigers | Clete Thomas profile |
| 2010 | Topps | Regular Issue | 442 | San Francisco Giants | Dan Runzler p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 443 | Colorado Rockies | Jason Hammel profile |
| 2010 | Topps | Regular Issue | 444 | Kansas City Royals | Yuniesky Betancourt profile |
| 2010 | Topps | Regular Issue | 445 | Colorado Rockies | Miguel Olivo profile |
| 2010 | Topps | Regular Issue | 446 | Chicago White Sox | Gavin Floyd profile |
| 2010 | Topps | Regular Issue | 447 | Baltimore Orioles | Jeremy Guthrie profile |
| 2010 | Topps | Regular Issue | 448 | Kansas City Royals | Joakim Soria profile |
| 2010 | Topps | Regular Issue | 449 | Oakland Athletics | Ryan Sweeney profile |
| 2010 | Topps | Regular Issue | 450 | New York Mets | Omir Santos profile |
| 2010 | Topps | Regular Issue | 451 | Seattle Mariners | Michael Saunders profile |
| 2010 | Topps | Regular Issue | 452 | St. Louis Cardinals | Allen Craig of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 453 | Washington Nationals | Jesse English p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 454 | Los Angeles Dodgers | James Loney profile |
| 2010 | Topps | Regular Issue | 455 | St. Louis Cardinals | Franchise History |
| 2010 | Topps | Regular Issue | 456 | San Diego Padres | Clayton Richard profile |
| 2010 | Topps | Regular Issue | 457 | Seattle Mariners | Kanekoa Texeira p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 458 | San Francisco Giants | Todd Wellemeyer profile |
| 2010 | Topps | Regular Issue | 459 | Detroit Tigers | Joel Zumaya profile |
| 2010 | Topps | Regular Issue | 460 | San Diego Padres | Aaron Cunningham profile |
| 2010 | Topps | Regular Issue | 461 | Oakland Athletics | Tyson Ross p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 462 | Milwaukee Brewers | Alcides Escobar profile |
| 2010 | Topps | Regular Issue | 463 | Chicago Cubs | Carlos Marmol profile |
| 2010 | Topps | Regular Issue | 464 | Minnesota Twins | Francisco Liriano profile |
| 2010 | Topps | Regular Issue | 465 | Washington Nationals | Chien-Ming Wang profile |
| 2010 | Topps | Regular Issue | 466 | Los Angeles Angels | Jered Weaver profile |
| 2010 | Topps | Regular Issue | 467 | Cleveland Indians | Roberto Hernandez profile |
| 2010 | Topps | Regular Issue | 468 | Minnesota Twins | Delmon Young profile |
| 2010 | Topps | Regular Issue | 469 | Minnesota Twins | Alex Burnett p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 470 | New York Yankees | Team Card |
| 2010 | Topps | Regular Issue | 471 | Minnesota Twins | Drew Butera c - Rookie Card profile |
| 2010 | Topps | Regular Issue | 472 | Toronto Blue Jays | Team Card Adam Lind, Vernon Wells |
| 2010 | Topps | Regular Issue | 473 | Boston Red Sox | Jason Varitek profile |
| 2010 | Topps | Regular Issue | 474 | Philadelphia Phillies | Kyle Kendrick profile |
| 2010 | Topps | Regular Issue | 475 | Detroit Tigers | Johnny Damon profile |
| 2010 | Topps | Regular Issue | 476 | St. Louis Cardinals | Yadier Molina profile |
| 2010 | Topps | Regular Issue | 477 | Atlanta Braves | Nate McLouth profile |
| 2010 | Topps | Regular Issue | 478 | Arizona Diamondbacks | Conor Jackson profile |
| 2010 | Topps | Regular Issue | 479 | St. Louis Cardinals | Chris Carpenter profile |
| 2010 | Topps | Regular Issue | 480 | Boston Red Sox | Team Card |
| 2010 | Topps | Regular Issue | 481 | Cincinnati Reds | Scott Rolen profile |
| 2010 | Topps | Regular Issue | 482 | Toronto Blue Jays | Mike McCoy of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 483 | Boston Red Sox | Daisuke Matsuzaka profile |
| 2010 | Topps | Regular Issue | 484 | Chicago Cubs | Mike Fontenot profile |
| 2010 | Topps | Regular Issue | 485 | Washington Nationals | Jesus Flores profile |
| 2010 | Topps | Regular Issue | 486 | Philadelphia Phillies | Raul Ibanez profile |
| 2010 | Topps | Regular Issue | 487 | Florida Marlins | Dan Uggla profile |
| 2010 | Topps | Regular Issue | 488 | Pittsburgh Pirates | Delwyn Young profile |
| 2010 | Topps | Regular Issue | 489 | Los Angeles Dodgers | Russell Martin profile |
| 2010 | Topps | Regular Issue | 490 | Houston Astros | Michael Bourn profile |
| 2010 | Topps | Regular Issue | 491 | Los Angeles Dodgers | Rafael Furcal profile |
| 2010 | Topps | Regular Issue | 492 | San Francisco Giants | Brian Wilson profile |
| 2010 | Topps | Regular Issue | 493 | San Francisco Giants | Travis Ishikawa profile |
| 2010 | Topps | Regular Issue | 494 | Florida Marlins | Andrew Miller profile |
| 2010 | Topps | Regular Issue | 495 | Tampa Bay Rays | Carlos Pena profile |
| 2010 | Topps | Regular Issue | 496 | Oakland Athletics | Rajai Davis profile |
| 2010 | Topps | Regular Issue | 497 | San Francisco Giants | Edgar Renteria profile |
| 2010 | Topps | Regular Issue | 498 | Chicago White Sox | Sergio Santos p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 499 | Boston Red Sox | Mike Bowden profile |
| 2010 | Topps | Regular Issue | 500 | Philadelphia Phillies | Brad Lidge profile |
| 2010 | Topps | Regular Issue | 501 | Chicago White Sox | Jake Peavy profile |
| 2010 | Topps | Regular Issue | 502 | Colorado Rockies | Jhoulys Chacin profile |
| 2010 | Topps | Regular Issue | 503 | Detroit Tigers | Austin Jackson of - Rookie Card profile |
| 2010 | Topps | Regular Issue | 504 | Los Angeles Angels | Jeff Mathis profile |
| 2010 | Topps | Regular Issue | 505 | Cleveland Indians | Andy Marte profile |
| 2010 | Topps | Regular Issue | 506 | Seattle Mariners | Jose Lopez profile |
| 2010 | Topps | Regular Issue | 507 | New York Mets | Francisco Rodriguez profile |
| 2010 | Topps | Regular Issue | 508 | Kansas City Royals | Chris Getz profile |
| 2010 | Topps | Regular Issue | 509 | Colorado Rockies | Todd Helton profile |
| 2010 | Topps | Regular Issue | 510 | Arizona Diamondbacks | Diamondbacks to back Jacks Mark Reynolds, Justin Upton |
| 2010 | Topps | Regular Issue | 511 | Chicago Cubs | Franchise History |
| 2010 | Topps | Regular Issue | 512 | Los Angeles Angels | Scot Shields profile |
| 2010 | Topps | Regular Issue | 513 | Detroit Tigers | Scott Sizemore 2b - Rookie Card profile |
| 2010 | Topps | Regular Issue | 514 | Tampa Bay Rays | Rafael Soriano profile |
| 2010 | Topps | Regular Issue | 515 | Seattle Mariners | Franchise History |
| 2010 | Topps | Regular Issue | 516 | Chicago Cubs | Marlon Byrd profile |
| 2010 | Topps | Regular Issue | 517 | Oakland Athletics | Cliff Pennington profile |
| 2010 | Topps | Regular Issue | 518 | Milwaukee Brewers | Corey Hart profile |
| 2010 | Topps | Regular Issue | 519 | Minnesota Twins | Alexi Casilla profile |
| 2010 | Topps | Regular Issue | 520 | Chicago Cubs | Randy Wells profile |
| 2010 | Topps | Regular Issue | 521 | Detroit Tigers | Jeremy Bonderman profile |
| 2010 | Topps | Regular Issue | 522 | Atlanta Braves | Jordan Schafer profile |
| 2010 | Topps | Regular Issue | 523 | Detroit Tigers | Phil Coke profile |
| 2010 | Topps | Regular Issue | 524 | Kansas City Royals | Dusty Hughes p - Rookie Card profile |
| 2010 | Topps | Regular Issue | 525 | Cleveland Indians | David Huff profile |
| 2010 | Topps | Regular Issue | 526 | Detroit Tigers | Carlos Guillen dh profile |
| 2010 | Topps | Regular Issue | 527 | Los Angeles Angels | Brandon Wood profile |
| 2010 | Topps | Regular Issue | 528 | Kansas City Royals | Brian Bannister profile |
| 2010 | Topps | Regular Issue | 529 | Houston Astros | Carlos Lee profile |
| 2010 | Topps | Regular Issue | 530 | Pittsburgh Pirates | Steve Pearce profile |
| 2010 | Topps | Regular Issue | 531 | San Francisco Giants | Matt Cain profile |
| 2010 | Topps | Regular Issue | 532 | Houston Astros | Hunter Pence profile |
| 2010 | Topps | Regular Issue | 533 | New York Mets | Gary Matthews profile |
| 2010 | Topps | Regular Issue | 534 | Boston Red Sox | Hideki Okajima profile |
| 2010 | Topps | Regular Issue | 535 | Tampa Bay Rays | Andy Sonnanstine profile |
| 2010 | Topps | Regular Issue | 536 | Los Angeles Angels | Matt Palmer profile |
| 2010 | Topps | Regular Issue | 537 | Minnesota Twins | Michael Cuddyer profile |
| 2010 | Topps | Regular Issue | 538 | Cleveland Indians | Travis Hafner dh profile |
| 2010 | Topps | Regular Issue | 539 | Arizona Diamondbacks | Team Card |
| 2010 | Topps | Regular Issue | 540 | Tampa Bay Rays | Sean Rodriguez profile |
| 2010 | Topps | Regular Issue | 541 | St. Louis Cardinals | Jason Motte profile |
| 2010 | Topps | Regular Issue | 542 | San Diego Padres | Heath Bell profile |
| 2010 | Topps | Regular Issue | 543 | Baltimore Orioles | Classic Combo Adam Jones, Nick Markakis |
| 2010 | Topps | Regular Issue | 544 | Oakland Athletics | Kevin Kouzmanoff profile |
| 2010 | Topps | Regular Issue | 545 | San Francisco Giants | Fred Lewis profile |
| 2010 | Topps | Regular Issue | 546 | Houston Astros | Bud Norris profile |
| 2010 | Topps | Regular Issue | 547 | New York Yankees | Brett Gardner profile |
| 2010 | Topps | Regular Issue | 548 | Minnesota Twins | Franchise History |
| 2010 | Topps | Regular Issue | 549 | New York Yankees | Derek Jeter profile |
| 2010 | Topps | Regular Issue | 550 | Chicago White Sox | Freddy Garcia profile |
| 2010 | Topps | Regular Issue | 551 | San Diego Padres | Everth Cabrera profile |
| 2010 | Topps | Regular Issue | 552 | Baltimore Orioles | Chris Tillman profile |
| 2010 | Topps | Regular Issue | 553 | Florida Marlins | Team Card |
| 2010 | Topps | Regular Issue | 554 | Cincinnati Reds | Ramon Hernandez profile |
| 2010 | Topps | Regular Issue | 555 | Tampa Bay Rays | B.J. Upton profile |
| 2010 | Topps | Regular Issue | 556 | Chicago White Sox | Team Card |
| 2010 | Topps | Regular Issue | 557 | Toronto Blue Jays | Aaron Hill profile |
| 2010 | Topps | Regular Issue | 558 | Florida Marlins | Ronny Paulino profile |
| 2010 | Topps | Regular Issue | 559 | Baltimore Orioles | Nick Markakis profile |
| 2010 | Topps | Regular Issue | 560 | Seattle Mariners | Ryan Rowland-Smith profile |
| 2010 | Topps | Regular Issue | 561 | Washington Nationals | Ryan Zimmerman profile |
| 2010 | Topps | Regular Issue | 562 | Chicago White Sox | Carlos Quentin profile |
| 2010 | Topps | Regular Issue | 563 | Cincinnati Reds | Bronson Arroyo profile |
| 2010 | Topps | Regular Issue | 564 | Houston Astros | Franchise History |
| 2010 | Topps | Regular Issue | 565 | Colorado Rockies | Franklin Morales profile |
| 2010 | Topps | Regular Issue | 566 | Los Angeles Angels | Maicer Izturis profile |
| 2010 | Topps | Regular Issue | 567 | New York Mets | Mike Pelfrey profile |
| 2010 | Topps | Regular Issue | 568 | Texas Rangers | Jarrod Saltalamacchia profile |
| 2010 | Topps | Regular Issue | 569 | Boston Red Sox | Jacoby Ellsbury profile |
| 2010 | Topps | Regular Issue | 570 | Washington Nationals | Josh Willingham profile |
| 2010 | Topps | Regular Issue | 571 | Houston Astros | Brandon Lyon profile |
| 2010 | Topps | Regular Issue | 572 | Boston Red Sox | Clay Buchholz profile |
| 2010 | Topps | Regular Issue | 573 | New York Mets | Johan Santana profile |
| 2010 | Topps | Regular Issue | 574 | Milwaukee Brewers | Team Card |
| 2010 | Topps | Regular Issue | 575 | Detroit Tigers | Ryan Perry profile |
| 2010 | Topps | Regular Issue | 576 | Pittsburgh Pirates | Paul Maholm profile |
| 2010 | Topps | Regular Issue | 577 | Pittsburgh Pirates | Jason Jaramillo profile |
| 2010 | Topps | Regular Issue | 578 | San Francisco Giants | Aaron Rowand profile |
| 2010 | Topps | Regular Issue | 579 | Oakland Athletics | Trevor Cahill profile |
| 2010 | Topps | Regular Issue | 580 | Seattle Mariners | Ian Snell profile |
| 2010 | Topps | Regular Issue | 581 | Cincinnati Reds | Chris Dickerson profile |
| 2010 | Topps | Regular Issue | 582 | Atlanta Braves | Martin Prado profile |
| 2010 | Topps | Regular Issue | 583 | Florida Marlins | Anibal Sanchez profile |
| 2010 | Topps | Regular Issue | 584 | Washington Nationals | Matt Capps profile |
| 2010 | Topps | Regular Issue | 585 | Tampa Bay Rays | Dioner Navarro profile |
| 2010 | Topps | Regular Issue | 586 | Houston Astros | Roy Oswalt profile |
| 2010 | Topps | Regular Issue | 587 | Texas Rangers | David Murphy profile |
| 2010 | Topps | Regular Issue | 588 | Oakland Athletics | Landon Powell profile |
| 2010 | Topps | Regular Issue | 589 | Cincinnati Reds | Edinson Volquez profile |
| 2010 | Topps | Regular Issue | 590 | Philadelphia Phillies | Ryan Howard profile |
| 2010 | Topps | Regular Issue | 591 | Los Angeles Angels | Fernando Rodney profile |
| 2010 | Topps | Regular Issue | 592 | Baltimore Orioles | Brian Roberts profile |
| 2010 | Topps | Regular Issue | 593 | Texas Rangers | Derek Holland profile |
| 2010 | Topps | Regular Issue | 594 | Pittsburgh Pirates | Andy LaRoche profile |
| 2010 | Topps | Regular Issue | 595 | Boston Red Sox | Mike Lowell profile |
| 2010 | Topps | Regular Issue | 596 | St. Louis Cardinals | Brendan Ryan profile |
| 2010 | Topps | Regular Issue | 597 | Houston Astros | J.R. Towles profile |
| 2010 | Topps | Regular Issue | 598 | Kansas City Royals | Alberto Callaspo profile |
| 2010 | Topps | Regular Issue | 599 | Cincinnati Reds | Jay Bruce profile |
| 2010 | Topps | Regular Issue | 600 | Florida Marlins | Hanley Ramirez profile |
| 2010 | Topps | Regular Issue | 601 | Los Angeles Dodgers | Blake DeWitt profile |
| 2010 | Topps | Regular Issue | 602 | Kansas City Royals | Franchise History |
| 2010 | Topps | Regular Issue | 603 | Arizona Diamondbacks | Gerardo Parra profile |
| 2010 | Topps | Regular Issue | 604 | Atlanta Braves | Franchise History |
| 2010 | Topps | Regular Issue | 605 | Chicago White Sox | A.J. Pierzynski profile |
| 2010 | Topps | Regular Issue | 606 | Arizona Diamondbacks | Chad Qualls profile |
| 2010 | Topps | Regular Issue | 607 | Colorado Rockies | Ubaldo Jimenez profile |
| 2010 | Topps | Regular Issue | 608 | Pittsburgh Pirates | Team Card |
| 2010 | Topps | Regular Issue | 609 | Milwaukee Brewers | Jeff Suppan profile |
| 2010 | Topps | Regular Issue | 610 | Kansas City Royals | Alex Gordon profile |
| 2010 | Topps | Regular Issue | 611 | Oakland Athletics | Josh Outman profile |
| 2010 | Topps | Regular Issue | 612 | Pittsburgh Pirates | Lastings Milledge profile |
| 2010 | Topps | Regular Issue | 613 | Oakland Athletics | Eric Chavez dh profile |
| 2010 | Topps | Regular Issue | 614 | Arizona Diamondbacks | Kelly Johnson profile |
| 2010 | Topps | Regular Issue | 615 | Detroit Tigers | Justin Verlander profile |
| 2010 | Topps | Regular Issue | 616 | Seattle Mariners | Franklin Gutierrez profile |
| 2010 | Topps | Regular Issue | 617 | Cleveland Indians | Luis Valbuena profile |
| 2010 | Topps | Regular Issue | 618 | Florida Marlins | Jorge Cantu profile |
| 2010 | Topps | Regular Issue | 619 | Los Angeles Angels | Mike Napoli profile |
| 2010 | Topps | Regular Issue | 620 | Chicago Cubs | Geovany Soto profile |
| 2010 | Topps | Regular Issue | 621 | Colorado Rockies | Aaron Cook profile |
| 2010 | Topps | Regular Issue | 622 | Cleveland Indians | Franchise History |
| 2010 | Topps | Regular Issue | 623 | Detroit Tigers | Miguel Cabrera profile |
| 2010 | Topps | Regular Issue | 624 | New York Mets | Carlos Beltran profile |
| 2010 | Topps | Regular Issue | 625 | Cleveland Indians | Grady Sizemore cf profile |
| 2010 | Topps | Regular Issue | 626 | Minnesota Twins | Glen Perkins profile |
| 2010 | Topps | Regular Issue | 627 | Boston Red Sox | Jeremy Hermida profile |
| 2010 | Topps | Regular Issue | 628 | Washington Nationals | Ross Detwiler profile |
| 2010 | Topps | Regular Issue | 629 | New York Mets | Oliver Perez profile |
| 2010 | Topps | Regular Issue | 630 | Philadelphia Phillies | Ben Francisco profile |
| 2010 | Topps | Regular Issue | 631 | Toronto Blue Jays | Marc Rzepczynski profile |
| 2010 | Topps | Regular Issue | 632 | Oakland Athletics | Daric Barton profile |
| 2010 | Topps | Regular Issue | 633 | Boston Red Sox | Daniel Bard profile |
| 2010 | Topps | Regular Issue | 634 | Seattle Mariners | Casey Kotchman profile |
| 2010 | Topps | Regular Issue | 635 | Minnesota Twins | Carl Pavano profile |
| 2010 | Topps | Regular Issue | 636 | Tampa Bay Rays | Classic Combo Evan Longoria, B.J. Upton |
| 2010 | Topps | Regular Issue | 637 | New York Yankees | Classic Combo Lou Gehrig, Babe Ruth |
| 2010 | Topps | Regular Issue | 638 | Chicago White Sox | Paul Konerko profile |
| 2010 | Topps | Regular Issue | 639 | Los Angeles Dodgers | Team Card Andre Ethier, Matt Kemp, Manny Ramirez |
| 2010 | Topps | Regular Issue | 640 | Atlanta Braves | Matt Diaz profile |
| 2010 | Topps | Regular Issue | 641 | Detroit Tigers | Chase Headley profile |
| 2010 | Topps | Regular Issue | 642 | San Diego Padres | Tony Gwynn Franchise History profile |
| 2010 | Topps | Regular Issue | 643 | Texas Rangers | Michael Young profile |
| 2010 | Topps | Regular Issue | 644 | Toronto Blue Jays | David Purcey profile |
| 2010 | Topps | Regular Issue | 645 | Texas Rangers | Team Card |
| 2010 | Topps | Regular Issue | 646 | Cleveland Indians | Trevor Crowe profile |
| 2010 | Topps | Regular Issue | 647 | Chicago Cubs | Alfonso Soriano profile |
| 2010 | Topps | Regular Issue | 648 | Los Angeles Angels | Brian Fuentes profile |
| 2010 | Topps | Regular Issue | 649 | Milwaukee Brewers | Casey McGehee profile |
| 2010 | Topps | Regular Issue | 650 | Boston Red Sox | Dustin Pedroia profile |
| 2010 | Topps | Regular Issue | 651 | Colorado Rockies | Mike Aviles profile |
| 2010 | Topps | Regular Issue | 652 | Atlanta Braves | Chipper Jones profile |
| 2010 | Topps | Regular Issue | 653 | Baltimore Orioles | Nolan Reimold profile |
| 2010 | Topps | Regular Issue | 654 | Washington Nationals | Collin Balester profile |
| 2010 | Topps | Regular Issue | 655 | Philadelphia Phillies | Ryan Madson profile |
| 2010 | Topps | Regular Issue | 656 | Boston Red Sox | Jon Lester profile |
| 2010 | Topps | Regular Issue | 657 | San Diego Padres | Chris Young profile |
| 2010 | Topps | Regular Issue | 658 | Texas Rangers | Tommy Hunter profile |
| 2010 | Topps | Regular Issue | 659 | Minnesota Twins | Nick Blackburn profile |
| 2010 | Topps | Regular Issue | 660 | Texas Rangers | Brandon McCarthy profile |
