| Matt Hall | RP | 25.307 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Gregory Soto | p | 24.104 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Cal Quantrill | P | 24.105 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Luis Perdomo | SP | 26.017 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Richard Lovelady | P | 23.324 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Casey Sadler | P | 28.317 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Tyler Glasnow | SP | 25.276 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Transferred to 60-day DL |
| Garrett Stubbs | C | 26.000 | Houston Astros | Houston Astros (MLB) | Recalled from Round Rock (AAA) |
| Max Stassi | C | 28.072 | Houston Astros | Houston Astros (MLB) | DL-10 Left knee soreness |
| Darwinzon Hernandez | P | 22.160 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Portland (AA) |
| Colten Brewer | RP | 26.209 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Jacob Waguespack | P | 25.202 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Tim Mayza | P | 27.132 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Left unlar neuritis |
| Jose Osuna | RF | 26.165 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Activated from DL |
| Francisco Cervelli | C | 33.081 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-7 Concussion |
| Jake Elmore | 2B | 31.346 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Designated for Assignment |
| Jacob Stallings | C | 29.155 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Sam Coonrod | P | 26.246 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Andrew Suarez | P | 26.257 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Andrew Heaney | SP | 27.356 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Jaime Barria | SP | 22.312 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Evan Phillips | p | 24.257 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Chris Davis | 1B | 33.070 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-10 Left hip inflammation |
| Austin Adams | P | 32.280 | Detroit Tigers | Detroit Tigers (MLB) | Claimed off waivers from Twins by Tigers |
| Ryan Feierabend | P | 33.277 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to minors |
| Tyler Naquin | CF | 28.032 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) for rehab |
| Carlos Gonzalez | RF | 33.221 | | | Released by Indians |
| Tim Peterson | P | 28.093 | New York Mets | Syracuse (AAA) | Outrighted to minors |
| Paul Sewald | RP | 29.000 | New York Mets | Syracuse (AAA) | Outrighted to minors |
| Jose Altuve | 2B | 29.020 | Houston Astros | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Jeremy Fernandez | IF | 21.319 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Greg Mahle | P | 26.039 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Parker Joe Robinson | P | 23.284 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Alex Klonowski | P | 27.055 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to Arizona Angels (Rk) |
| Narciso Crook | RF | 23.319 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Offerman Collado | 2B | 22.350 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Jonathan Aro | P | 28.228 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Kevin Santiago | SS | 21.240 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Ryan Metzler | IF | 26.067 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| Tyler Schimpf | P | 23.293 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Gustavo Polanco | C | 21.347 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Tim Melville | P | 29.229 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Nelson Gonzalez | P | 29.100 | Colorado Rockies | Boise (A-) | Assigned to Boise (A-) |
| Charlie Madden | C | 23.268 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Manny Ramirez | P | 19.187 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Dylan Hardy | IF-OF | 22.126 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Hagen Owenby | C-IF | 23.310 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Kris Jackson | P | 23.067 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Ricardo Rodriguez | C | 21.157 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Tyler Dearden | CF | 20.324 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Jake Palomaki | IF | 23.314 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| DJ Artis | OF | 22.067 | Chicago Cubs | South Bend (A) | DL-7 Injured |
| Joe Shaw | P | 25.157 | New York Mets | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Shawn Semple | P | 23.230 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Vidal Brujan | 2B | 21.106 | Tampa Bay Rays | Charlotte (A+) | DL-7 Injured |
| Andrew Istler | P-OF | 26.250 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Joantgel Segovia | OF | 22.199 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Wladimir Galindo | 3B | 22.201 | Chicago Cubs | Myrtle Beach (A+) | DL-7 Injured |
| DJ Wilson | OF | 22.230 | Chicago Cubs | Myrtle Beach (A+) | Activated from disabled list |
| Nick Sciortino | IF-C | 23.310 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Cooper Criswell | P | 22.306 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Lorenzo Quintana | C | 30.086 | Houston Astros | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Carlos Canelon | C | 24.163 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Wendolyn Bautista | P | 26.060 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Andres Santiago | P | 29.212 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Michael O'Neill | OF | 26.348 | Milwaukee Brewers | San Antonio (AAA) | Assigned to San Antonio (AAA) |
| Daniel Gonzalez | C | 23.172 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Brendan McKay | P | 23.160 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Josh Fleming | P | 23.008 | Tampa Bay Rays | Montgomery (AA) | Activated from disabled list |
| Grenny Cumana | SS | 23.198 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Carlos Navas | P | 26.286 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Francisco Jimenez | P | 24.234 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Alexis Rivero | P | 24.220 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Tanner Chleborad | P | 26.203 | Baltimore Orioles | Bowie (AA) | Placed on temporarily inactive list |
| Raul Rivas | 2B | 22.211 | Philadelphia Phillies | Reading (AA) | DL-7 Left shin contusion |
| Scotty Burcham | IF | 25.343 | Colorado Rockies | Hartford (AA) | Activated from disabled list |
| Tony Gonsolin | P | 25.012 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Nolan Fontana | SS | 27.355 | Texas Rangers | Nashville (AAA) | DL-7 Injured |
| Chase D'Arnaud | SS | 32.125 | Texas Rangers | Nashville (AAA) | Activated from disabled list |
| Sean Burnett | P | 36.251 | - | | Announced retirement |
| Luis Gonzalez | P | 27.130 | Baltimore Orioles | Norfolk (AAA) | Activated from disabled list |
| Anderson Feliz | 3B | 27.015 | Baltimore Orioles | Norfolk (AAA) | Placed on temporarily inactive list |
| Jason Coats | OF | 29.091 | Tampa Bay Rays | Durham (AAA) | DL-7 Injured |
| P.J. Conlon | P | 25.196 | New York Mets | Syracuse (AAA) | DL-7 Injured |
| Brady Lail | P | 25.290 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Activated from disabled list |
