| Scooter Gennett | 2B | 29.002 | Cincinnati Reds | Cincinnati Reds (MLB) | Transferred to 60-day DL |
| Matt Bowman | RP | 27.338 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Nick Senzel | IF | 23.309 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from minors |
| Tyson Ross | SP | 32.011 | Detroit Tigers | Detroit Tigers (MLB) | Reinstated to active roster |
| Skye Bolt | OF | 25.108 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Las Vegas (AAA) |
| Tony Barnette | RP | 35.176 | Chicago Cubs | Iowa (AAA) | Transferred to 60-day DL |
| Miguel Sano | 3B-DH | 25.357 | Minnesota Twins | Pensacola (AA) | Assigned to Pensacola (AA) for rehab |
| Touki Toussaint | P | 22.317 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Matt Duffy | 3B | 28.108 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) for rehab |
| Corey Kluber | SP | 33.023 | Cleveland Indians | Cleveland Indians (MLB) | DL-10 Right ulna fracture |
| Jonathan Edwards | P | 31.116 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Austin Brice | RP | 26.318 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Jarlin Garcia | RP | 26.105 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Christin Stewart | C-1B | 25.144 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) for rehab |
| Cody Asche | 3B | 28.307 | Boston Red Sox | Pawtucket (AAA) | Contract purchased from Sugar Land (Indy) |
| Tyler Beede | SP | 25.345 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Sacramento (AAA) |
| Mike Gerber | OF | 26.299 | San Francisco Giants | San Francisco Giants (MLB) | Contract purchased from minors |
| Gerardo Parra | RF | 31.363 | San Francisco Giants | San Francisco Giants (MLB) | Designated for Assignment |
| Erik Kratz | C | 38.322 | San Francisco Giants | San Francisco Giants (MLB) | DL-10 Left hamstring strain |
| Tim Locastro | LF | 26.293 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Chris Iannetta | C | 36.025 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Drew Butera | C | 35.268 | Colorado Rockies | Colorado Rockies (MLB) | Designated for Assignment |
| Tim Melville | P | 29.206 | Colorado Rockies | Albuquerque (AAA) | Contract purchased from Long Island (Indy) |
| Drew Smith | P | 25.221 | New York Mets | New York Mets (MLB) | Transferred to 60-day DL |
| Adeiny Hechavarria | SS | 30.018 | New York Mets | New York Mets (MLB) | Contract purchased from minors |
| Dominic Smith | 1B | 23.323 | New York Mets | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Jay Jackson | P | 31.189 | Milwaukee Brewers | El Paso (AAA) | Assigned to El Paso (AAA) |
| John Curtiss | P | 26.028 | Los Angeles Angels | Salt Lake (AAA) | Outrighted to minors |
| Travis D'Arnaud | C | 30.082 | | | Released by Mets |
| Adrian Houser | RP | 26.090 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from San Antonio (AAA) |
| Brett Kennedy | P | 24.272 | San Diego Padres | San Diego Padres (MLB) | Transferred to 60-day DL |
| Alex Dickerson | OF | 28.342 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from minors |
| Luis Perdomo | SP | 25.359 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Alen Hanson | 2B | 26.193 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Designated for Assignment |
| Derek Law | P | 28.231 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Ian Evans | IF | 22.297 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Stephan Vidal | C | 23.029 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Alberti Chavez | 2B-3B | 23.287 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Rafael Lantigua | 2B | 21.005 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Malique Ziegler | OF | 22.237 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Zach Soria | C | 25.186 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Jett Manning | SS | 21.355 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Tanner Gardner | IF-OF | 23.217 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Garrett Kelly | C-P | 24.274 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Brendan King | P | 24.299 | Chicago Cubs | Eugene (A-) | Assigned to Eugene (A-) |
| Daniel Schneemann | SS | 22.100 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Luke Eubank | P | 25.068 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| David Speer | P | 26.262 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Randolph Gassaway | 1B | 23.346 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Brennan Bernardino | P | 27.109 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Mike Gretler | SS | 23.123 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Franklin Van gurp | P-C | 23.190 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Elias Espino | P | 22.014 | Seattle Mariners | West Virginia (A) | DL-7 Injured |
| Miguel Aparacio | OF | 20.047 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Alejandro Kirk | C | 20.178 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Jordan Balazovic | P | 20.228 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Tanner Kirwer | OF | 23.049 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Bryan Valdez | P | 24.157 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Moises Gomez | P | 22.084 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Jordan Groshans | SS | 19.175 | Toronto Blue Jays | Lansing (A) | DL-7 Injured |
| Marcos Gonzalez | SS | 19.204 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Marty Costes | OF | 23.137 | Houston Astros | Quad Cities (A) | DL-7 Injured |
| Riley Adams | C | 22.311 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Dauri Moreta | P | 23.018 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Mark Contreras | IF | 24.099 | Milwaukee Brewers | Pensacola (AA) | Assigned to Pensacola (AA) |
| Benton Moss | P | 26.071 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Tanner Dodson | P | 21.359 | Tampa Bay Rays | Charlotte (A+) | Activated from disabled list |
| Ryan Olson | P | 24.162 | Cincinnati Reds | Daytona (A+) | DL-7 Injured |
| Ronaldo Hernandez | C | 21.173 | Tampa Bay Rays | Charlotte (A+) | Reinstated to active roster |
| J.C. Cloney | P | 24.273 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Kyle Nelson | P | 22.299 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Josh Mitchell | P | 24.237 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Blake Perkins | OF | 22.235 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| DJ Wilson | OF | 22.207 | Chicago Cubs | Myrtle Beach (A+) | DL-7 Injured |
| Cesar Rosado | P | 22.315 | Houston Astros | Fayetteville (A+) | DL-7 Injured |
| Zach Davis | OF | 24.308 | Chicago Cubs | Myrtle Beach (A+) | Activated from disabled list |
| Nate Easley | 2B | 23.113 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Sandro Cabrera | P | 23.316 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Carlos Sano | P | 26.068 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Caleb Baragar | P | 25.024 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Brandon Van Horn | IF | 25.136 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Evan Miller | P | 23.346 | San Diego Padres | Lake Elsinore (A+) | Placed on temporarily inactive list |
| Stephen Wrenn | OF | 24.208 | Houston Astros | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Paco Rodriguez | P | 28.017 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Carmen Benedetti | IF | 24.186 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Travis Radke | P | 26.058 | San Diego Padres | Amarillo (AA) | Activated from disabled list |
| Ivan Castillo | SS | 23.339 | San Diego Padres | Amarillo (AA) | Activated from disabled list |
| Dusten Knight | P | 28.238 | - | | Released by Pensacola |
| Matt Tomshaw | P | 30.137 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Dylan Lee | P | 24.275 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Cody Poteet | P | 24.277 | Miami Marlins | Jacksonville (AA) | Placed on temporarily inactive list |
| Zack Kelly | P | 24.061 | Los Angeles Angels | Mobile (AA) | Activated from disabled list |
| Jakob Hernandez | P | 22.349 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Lucas Long | P | 26.208 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| James Karinchak | P | 23.224 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Mario Sanchez | P | 24.184 | Washington Nationals | Fresno (AAA) | Assigned to Fresno (AAA) |
| Nick Lovullo | SS | 25.153 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Logan Ondrusek | P | 34.079 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Brandon Grudzielanek | IF-OF | 23.343 | Toronto Blue Jays | New Hampshire (AA) | DL-7 Injured |
| Kieran Lovegrove | P | 24.279 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Scotty Burcham | IF | 25.320 | Colorado Rockies | Hartford (AA) | DL-7 Injured |
| Jeremy Rivera | SS | 24.093 | Boston Red Sox | Portland (AA) | Activated from disabled list |
| Zac Lowther | P | 23.003 | Baltimore Orioles | Bowie (AA) | Placed on temporarily inactive list |
| Tim Melville | P | 29.206 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Brian Mundell | C | 25.064 | Colorado Rockies | Albuquerque (AAA) | Activated from disabled list |
| Elliot Soto | SS | 29.255 | Colorado Rockies | Albuquerque (AAA) | DL-7 Injured |
| Nolan Fontana | SS | 27.332 | Texas Rangers | Nashville (AAA) | DL-7 Injured |
| Akeem Bostick | P | 23.365 | Houston Astros | Round Rock (AAA) | Placed on temporarily inactive list |
| Blake Gailen | OF | 34.037 | Los Angeles Dodgers | Oklahoma City (AAA) | Activated from disabled list |
| Bryan Mitchell | P | 28.014 | San Diego Padres | El Paso (AAA) | DL-7 Injured |
| Corey Ray | CF | 24.223 | Milwaukee Brewers | San Antonio (AAA) | Activated from disabled list |
| Abraham Almonte | OF | 29.316 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Troy Scribner | P | 27.306 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Courtney Hawkins | OF | 25.172 | - | | Released by Reds |
| Cody Asche | 3B | 28.307 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Chad De La Guerra | IF | 26.160 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Bryan Alcala | P | 21.262 | - | | Announced retirement |
| Braden Bristo | P | 24.183 | New York Yankees | Tampa (A+) | Placed on temporarily inactive list |
| Matt Koch | SP | 28.182 | Arizona Diamondbacks | Reno (AAA) | Outrighted to minors |
| Caleb Simpson | P | 27.231 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
