| Shane Carle | RP | 26.343 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Right shoulder inflammation |
| Max Fried | P | 24.201 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Left groin strain |
| Deven Marrero | 2B | 27.347 | Arizona Diamondbacks | Reno (AAA) | Activated from DL and designated for assignment |
| Williams Jerez | CF | 26.083 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Nick Tropeano | SP | 27.345 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-10 Right shoulder inflammation |
| Joshua Fields | RP | 32.353 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to AZL Dodgers (Rk) for rehab |
| Matt Albers | RP | 35.199 | Milwaukee Brewers | Milwaukee Brewers (MLB) | DL-10 Strained left hamstring |
| Jon Perrin | P | 25.076 | Kansas City Royals | Northwest Arkansas (AA) | Traded from Brewers to Royals for Sal Biasi |
| Sal Biasi | P | 22.312 | Milwaukee Brewers | Wisconsin (A) | Traded from Royals to Brewers for Jon Perrin |
| Craig Gentry | RF | 34.252 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) for rehab |
| Jacob Turner | P | 27.078 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Hyun-Jin Ryu | SP | 31.135 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) for rehab |
| Chris Bostick | SS-2B | 25.136 | Pittsburgh Pirates | Indianapolis (AAA) | Designated for Assignment |
| Enyel De Los Santos | p | 22.226 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Dylan Cozens | OF | 24.068 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Brandon Mann | P | 34.083 | Texas Rangers | Round Rock (AAA) | Designated for Assignment |
| Hugh Smith | P | 21.135 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | DL-7 Injured |
| John Valente | 3B | 23.045 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Jorge Baez | P | 23.090 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | DL-7 Injured |
| Jose Appleton | P | 21.036 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | DL-7 Injured |
| Gabriel Gonzalez | P | 19.298 | New York Yankees | Gulf Coast Yankees (Rk) | |
| Oscar Rojas | P | 19.094 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Connor Scott | OF | 18.304 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Casey Crosby | P | 29.324 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Jacob Zanon | CF | 23.043 | New York Mets | Gulf Coast Mets (Rk) | Assigned to Gulf Coast Mets (Rk) |
| Ian Hardman | P | 22.326 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Eddie Jimenez | P | 22.364 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Will Banfield | C | 18.263 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Osiris Johnson | SS | 17.293 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Gabriel Mora | C | 18.067 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Miguel Torres | C | 18.157 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Justin Connell | OF | 19.149 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Carlos Soto | C | 19.102 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Assigned to Gulf Coast Cardinals (Rk) |
| Julio Frias | P | 20.067 | Miami Marlins | Gulf Coast Marlins (Rk) | |
| Travis Herrin | P | 23.100 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to Arizona Angels (Rk) |
| William Hancock | C | 21.280 | Kansas City Royals | Arizona Royals (Rk) | Assigned to Arizona Royals (Rk) |
| Bailey Clark | P | 23.247 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Elio Serrano | P | 20.005 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Trevor Larnach | OF | 21.162 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Carlos Narvaez | C | 19.254 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Jean Carlos Arias | OF | 20.205 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Jeffrey Rosa | P | 23.063 | - | | Released by Rays |
| Norwith Gudino | P | 22.259 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Carlos Sano | P | 25.164 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Rio Gomez | P | 23.291 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Gregori Rivero | C | 22.072 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Yeizo Campos | P | 22.100 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Ryan O'Rourke | P | 30.099 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| J.D. Osborne | C | 23.025 | Miami Marlins | Batavia (A-) | Assigned to Batavia (A-) |
| Sebastian Rivero | C | 19.264 | Kansas City Royals | Lexington (A) | Activated from disabled list |
| Jake Simon | P | 21.198 | New York Mets | Columbia (A) | DL-7 Injured |
| Quincy Nieporte | 1B-C | 24.009 | Philadelphia Phillies | Lakewood (A) | DL-7 Injured |
| Hildemaro Requena | P | 21.018 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Tyler Thomas | P | 22.229 | Texas Rangers | Hickory (A) | DL-7 Injured |
| Tristan Pompey | OF | 21.137 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Austin Glorius | P | 25.089 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Matt Whatley | C | 22.213 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Rodrigo Ayarza | 2B | 23.168 | - | | Released by Marlins |
| Nick Hill | OF | 24.005 | San Francisco Giants | Augusta (A) | |
| Elehuris Montero | 3B | 19.355 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Aaron Leasher | P | 22.101 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Sal Biasi | P | 22.312 | Milwaukee Brewers | Wisconsin (A) | Assigned to Wisconsin (A) |
| Christian Cavaness | OF | 24.144 | - | | Released by Twins |
| Bailey Falter | P | 21.105 | Philadelphia Phillies | Clearwater (A+) | Activated from disabled list |
| Cole Peterson | SS | 23.005 | Detroit Tigers | Lakeland (A+) | DL-7 Injured |
| Kellin Deglan | C | 26.096 | New York Yankees | Tampa (A+) | DL-7 Injured |
| McKenzie Mills | P | 22.262 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Jose Martinez | SS | 21.357 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Herlis Rodriguez | OF | 24.058 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Aaron Knapp | OF | 23.276 | - | | Released by Marlins |
| Wil Crowe | P | 23.332 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Anderson Polanco | P | 25.335 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Darwinzon Hernandez | P | 21.233 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Nolan Brown | OF | 24.206 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Taylor Guilbeau | P | 25.087 | Washington Nationals | Potomac (A+) | Activated from disabled list |
| Brandon Bailey | P | 23.292 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Nathan Rodriguez | C | 22.312 | Milwaukee Brewers | Carolina (A+) | DL-7 Injured |
| Luis Robert | OF | 21.004 | Chicago White Sox | Winston-Salem (A+) | Activated from disabled list |
| Bryan Brickhouse | P | 26.062 | Kansas City Royals | Wilmington (A+) | Assigned to Wilmington (A+) |
| Josh Mitchell | P | 23.333 | Kansas City Royals | Wilmington (A+) | DL-7 Injured |
| Adrian Morejon | P | 19.161 | San Diego Padres | Lake Elsinore (A+) | DL-7 Injured |
| Ryan Moseley | P | 23.305 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Reinstated to active roster |
| Ian Gardeck | P | 27.259 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Ramon Urias | 2B | 24.065 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Jon Perrin | P | 25.076 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| Todd Van Steensel | P | 27.205 | - | | Released by Twins |
| Wirkin Estevez | P | 26.145 | - | | Released by Nationals |
| Bralin Jackson | OF | 24.248 | Pittsburgh Pirates | Altoona (AA) | DL-7 Injured |
| Drew Muren | OF | 29.258 | - | | Released by Blue Jays |
| Aramis Garcia | C | 25.207 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Jose Garcia | C | 23.277 | - | | Released by Mets |
| Jin-De Jhang | C | 25.082 | Pittsburgh Pirates | Altoona (AA) | Activated from disabled list |
| Max Schrock | SS | 23.299 | St. Louis Cardinals | Memphis (AAA) | DL-7 Injured |
| Carlos Perez | C | 27.284 | Texas Rangers | Round Rock (AAA) | Activated from disabled list |
| Wilfredo Tovar | SS | 26.362 | St. Louis Cardinals | Memphis (AAA) | DL-7 Injured |
| Zac Curtis | P | 26.034 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Jerry Sands | OF | 30.314 | - | | Released by Giants |
| Chad Huffman | OF | 33.100 | Detroit Tigers | Toledo (AAA) | Activated from disabled list |
| Ivan DeJesus | 2B | 31.098 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Xavier Avery | OF | 28.218 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| D.J. Snelten | P | 26.070 | Baltimore Orioles | Norfolk (AAA) | Activated from disabled list |
| Forrest Snow | P | 29.220 | Tampa Bay Rays | Durham (AAA) | Activated from disabled list |
| Edwin Espinal | 1B | 24.196 | Detroit Tigers | Toledo (AAA) | Activated from disabled list |
| Luis Valbuena | 3B | 32.250 | | | Released by Angels |
| Buddy Boshers | RP | 30.090 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Claimed off waivers from Astros by Pirates |
| Zach McAllister | RP | 30.243 | | | Released by Indians |
| Brett Kennedy | P | 24.003 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from minors |
| Adam McCreery | P | 25.219 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Mississippi (AA) |
| Wes Parsons | P | 25.335 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Pat Venditte | RP | 33.038 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Sean Rodriguez | 1B-3B | 33.103 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-10 Left abdomen strain |
| Chad Bettis | RP | 29.103 | Colorado Rockies | Colorado Rockies (MLB) | Activated from DL |
| Tom Murphy | C | 27.126 | Colorado Rockies | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Brandon Drury | 3B | 25.351 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-10 Left hand fracture |
| Richard Urena | SS | 22.163 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Matt Belisle | P | 38.062 | Minnesota Twins | Minnesota Twins (MLB) | DL-10 Right knee chondromalacia |
| Matt Magill | RP | 28.270 | Minnesota Twins | Minnesota Twins (MLB) | Reinstated to active roster |
| J.B. Wendelken | P | 25.136 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Ryan Dull | RP | 28.309 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Chad Pinder | SS | 26.131 | Oakland Athletics | Oakland Athletics (MLB) | Activated from DL |
| John Brebbia | RP | 28.069 | St. Louis Cardinals | Memphis (AAA) | DL-10 Right forearm tightness |
| Ariel Hernandez | P | 26.158 | Milwaukee Brewers | Colorado Springs (AAA) | Claimed off waivers from Dodgers by Brewers and assigned to Colorado Springs (AAA) |
| Jesse Hahn | SP | 29.008 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Kolby Allard | RP | 20.359 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Greg Holland | P | 32.260 | Washington Nationals | Washington Nationals (MLB) | Signed to 1-year contract for 2018-2018 ($0m) [Free Agent] |
| Jefry Rodriguez | p | 25.012 | Washington Nationals | Washington Nationals (MLB) | Recalled from Syracuse (AAA) |
| Jimmy Cordero | P | 26.293 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Rene Rivera | C | 35.007 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) for rehab |
| Andres Santiago | P | 28.285 | Atlanta Braves | Gwinnett (AAA) | Activated from disabled list |
| Omar Martinez | C | 17.033 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Brandon Baker | P | 23.122 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Zach Penrod | P | 21.052 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Daniel Hudson | P | 31.151 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Right forearm tightness |
| Chase Whitley | P | 29.054 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Zac Curtis | RP | 26.034 | Texas Rangers | Round Rock (AAA) | Claimed off waivers from Phillies by Rangers |
