| Josh Rogers | P | 24.015 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Scott Schebler | RF | 27.292 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) for rehab |
| German Marquez | SP | 23.153 | Colorado Rockies | Colorado Rockies (MLB) | Placed on restricted list |
| Randall Delgado | RP | 28.166 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Designated for Assignment |
| Matt Andriese | RP | 28.331 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Traded from Rays to Diamondbacks for Michael Perez and Brian Shaffer |
| Michael Perez | C | 25.352 | Tampa Bay Rays | Durham (AAA) | Traded from Diamondbacks with Brian Shaffer to Rays for Matt Andriese |
| Brian Shaffer | P | 21.347 | Tampa Bay Rays | Charlotte (A+) | Traded from Diamondbacks with Michael Perez to Rays for Matt Andriese |
| Chris Tillman | SP | 30.101 | | | Granted free agency |
| David Hess | P | 25.015 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Taylor Featherston | 2B | 28.290 | Cincinnati Reds | Cincinnati Reds (MLB) | Signed to Minor League Contract |
| John Barbato | RP | 26.014 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) for rehab |
| Stephen Strasburg | SP | 30.005 | Washington Nationals | Washington Nationals (MLB) | DL-10 Injured |
| Gleyber Torres | SS | 21.224 | New York Yankees | New York Yankees (MLB) | Activated from DL |
| Jonny Venters | P | 33.127 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Activated from DL |
| Adam Frazier | DH | 26.224 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Casey Sadler | P | 28.012 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Zac Rosscup | RP | 30.046 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-10 Left middle finger inflammation |
| Pedro Baez | RP | 30.136 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Activated from DL |
| Jake Thompson | SP | 24.175 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Mitchell Walding | SS | 25.318 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Scott Hurst | OF | 22.122 | St. Louis Cardinals | Gulf Coast Cardinals (Rk) | Assigned to Gulf Coast Cardinals (Rk) |
| Ryan Lillie | P | 22.085 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) for rehab |
| Jacob Wilson | 2B | 27.361 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Jose Jimenez | P | 21.230 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Terence Connelly | IF | 24.140 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Jacob Polancic | P | 20.047 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Rayneldy Rosario | OF | 20.086 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Reshard Munroe | OF | 22.040 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Zach Hoffpauir | OF | 24.307 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Carlos Hernandez | P | 24.090 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Luis Castillo | P | 23.137 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Luis Aquino | P | 25.025 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Keenan Bartlett | P | 22.302 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Austin Glorius | P | 25.076 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Jhalan Jackson | OF | 25.163 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Christopher Torres | SS | 20.169 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Garvis Lara | SS | 22.067 | Miami Marlins | Greensboro (A) | DL-7 Injured |
| Anthony Villa | 1B | 24.118 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| Malique Ziegler | OF | 21.320 | San Francisco Giants | Augusta (A) | Activated from disabled list |
| Nick Hill | OF | 23.357 | San Francisco Giants | Richmond (AA) | Assigned to Richmond (AA) |
| Matthew Hardy | P | 23.010 | Milwaukee Brewers | Wisconsin (A) | Reinstated to active roster |
| Garrett Hope | C | 24.210 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Ryan Lawlor | P | 24.198 | Chicago Cubs | South Bend (A) | DL-7 Injured |
| Brian Shaffer | P | 21.347 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Malik Collymore | 2B | 23.087 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Jeff Bain | P | 22.144 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) |
| Michael Cruz | C | 22.194 | Chicago Cubs | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Brian Shaffer | P | 21.347 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Zech Lemond | P | 25.289 | Miami Marlins | Jupiter (A+) | Activated from disabled list |
| Vincenzo Aiello | P | 23.353 | Miami Marlins | Jupiter (A+) | DL-7 Injured |
| Brett Cumberland | C | 23.030 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| David Sopilka | C | 24.329 | Arizona Diamondbacks | Visalia (A+) | Activated from disabled list |
| Richie Fecteau | 2B | 24.130 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Marcus Wilson | OF | 21.344 | Arizona Diamondbacks | Visalia (A+) | DL-7 Injured |
| Justin Topa | P | 27.140 | Texas Rangers | Frisco (AA) | DL-7 Injured |
| Edgar Arredondo | P | 21.070 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Taylor Featherston | 2B | 28.290 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Connor Lien | OF | 24.132 | Atlanta Braves | Mississippi (AA) | DL-7 Injured |
| Brian Olson | C | 25.185 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Ryan Eades | P | 26.223 | Minnesota Twins | Chattanooga (AA) | Activated from disabled list |
| Greg Mahle | P | 25.099 | Los Angeles Angels | Mobile (AA) | Assigned to Mobile (AA) |
| Sean Isaac | P | 25.220 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Taylor Sparks | 3B | 25.113 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Harol Gonzalez | P | 23.145 | New York Mets | Binghamton (AA) | Reinstated to active roster |
| Jose Garcia | C | 23.264 | New York Mets | Binghamton (AA) | DL-7 Injured |
| Stephen Bruno | 2B | 27.250 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Scott Heineman | OF | 25.233 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Luis Pena | P | 22.336 | Los Angeles Angels | Salt Lake (AAA) | Placed on temporarily inactive list |
| Garrett Kennedy | C | 25.224 | Seattle Mariners | Tacoma (AAA) | Placed on temporarily inactive list |
| Jason Leblebijian | 3B-1B | 27.073 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Steve Geltz | P | 30.267 | Philadelphia Phillies | Lehigh Valley (AAA) | DL-7 Injured |
| Asher Wojciechowski | P | 29.216 | Chicago White Sox | Charlotte (AAA) | Signed to Minor League Contract |
| Michael Perez | C | 25.352 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Kyle Martin | P | 27.188 | - | | Released by Red Sox |
| Ryan Carpenter | SP | 27.337 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) for rehab |
| Freddy Peralta | P | 22.051 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Wisconsin (A) |
| Brett Phillips | OF | 24.056 | Milwaukee Brewers | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Dylan Floro | P | 27.210 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Walker Buehler | SP | 23.362 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Oklahoma City (AAA) |
| Tyler Wade | SS | 23.244 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Luis Cessa | SP | 26.091 | New York Yankees | New York Yankees (MLB) | Recalled from Scranton/Wilkes-Barre (AAA) |
| Chih-Wei Hu | P | 24.263 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Austin Pruitt | RP | 28.328 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Nathan Eovaldi | SP | 28.162 | Boston Red Sox | Boston Red Sox (MLB) | Traded from Rays to Red Sox for Jalen Beeks |
| Jalen Beeks | RP | 25.015 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Traded from Red Sox to Rays for Nathan Eovaldi |
| Luke Weaver | SP | 24.338 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Bryan Valdez | P | 23.240 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Andy Toelken | P | 22.192 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Luis Cossio | DH | 21.225 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Justin Garcia | P | 23.023 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Drew Avans | CF | 22.042 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Cash Gladfelter | 2B | 21.258 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| Alex King | SS | 22.296 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| L.T. Tolbert | P | 22.048 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Adrian Del Moral | P | 19.158 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Colton Pate | P | 22.178 | - | | Announced retirement |
| Doug Still | P | 22.358 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Geraldo Sanchez | P | 20.340 | - | | Released by Diamondbacks |
| Michel Gelabert | P | 21.199 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Al Jones | OF | 21.151 | Oakland Athletics | Arizona Athletics (Rk) | Assigned to Arizona Athletics (Rk) |
| Ty Buttrey | P | 25.116 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
