| TJ Rivera | 3B | 29.251 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) for rehab |
| Jabari Blash | RF | 29.001 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Mike Zunino | C | 27.102 | Seattle Mariners | Seattle Mariners (MLB) | DL-10 Left ankle bonue bruise |
| Carlos Perez | C | 27.251 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Matt Bowman | RP | 27.035 | St. Louis Cardinals | Memphis (AAA) | Activated from DL and assigned to Memphis (AAA) |
| Tyler O'Neill | c | 23.013 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-10 Left groin strain |
| Casey Coleman | P | 31.002 | Chicago Cubs | Chicago Cubs (MLB) | Signed to Minor League Contract |
| Dexter Fowler | RF | 32.105 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Reinstated to active roster |
| Martin Perez | SP | 27.092 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Jarrod Dyson | RF | 33.324 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-10 Right groin strain |
| Steven Souza | RF | 29.072 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Activated from DL |
| Jefry Marte | 1B | 27.014 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Tyler Saladino | 2B | 28.350 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Activated from DL |
| Eric Sogard | 2B | 32.044 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Designated for Assignment |
| Dillon Maples | P | 26.057 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Joey Krehbiel | P | 25.197 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Darnell Sweeney | SS | 27.154 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to minors |
| Blaine Boyer | RP | 36.359 | Kansas City Royals | Kansas City Royals (MLB) | Transferred to 60-day DL |
| Keith Skinner | C | 24.082 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Will Hibbs | P | 24.251 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Jose Quero | 1B | 19.303 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Teddy Hoffman | OF | 21.336 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Max Ryan | P | 21.027 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Kory Behenna | P | 21.337 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Signed to Minor League Contract |
| Estevan Florial | OF | 20.222 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jhonny Mateo | P | 23.320 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Yelin Rodriguez | P | 19.244 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Hector Martinez | 2B | 21.246 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Dylan Busby | OF | 22.220 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Austin Riley | 3B | 21.094 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Julio Martinez | OF | 20.202 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Corey Black | P | 26.336 | Chicago Cubs | Arizona Cubs (Rk) | Assigned to Arizona Cubs (Rk) |
| Stephen McGee | C | 27.148 | San Diego Padres | Arizona Padres 2 (Rk) | Assigned to Arizona Padres 2 (Rk) |
| Spencer Kulman | P | 23.098 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Riley Ottesen | P | 23.248 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Nick Snyder | P | 22.269 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Andre Jackson | P | 22.065 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Ledarious Clark | OF | 24.190 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) |
| Maiker Manzanillo | P | 21.264 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Cash Case | SS | 19.054 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Juan Martinez | 3B | 19.239 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Zeek White | OF | 21.179 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Joel Huertas | P | 22.142 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Josh Walker | P | 23.216 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Matt Albanese | OF-P | 22.345 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Max Wotell | P | 21.295 | - | | Released by Reds |
| Rickey Ramirez | P | 21.258 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Nestor Oronel | P | 21.204 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Domenic Mazza | P | 23.341 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Rafael Pujols | P | 22.319 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Stetson Woods | P | 23.171 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Adoni Kery | P | 22.138 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Erik Swanson | P | 24.304 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Miguel Eladio | SS | 22.056 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Telmito Agustin | OF | 21.269 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Cam Warner | IF | 24.123 | Detroit Tigers | West Michigan (A) | Assigned to West Michigan (A) |
| Tre' Gantt | OF | 22.056 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Danienger Perez | SS | 21.241 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Gregori Rivero | C | 22.039 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Ryan Koziol | P | 24.274 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Dalton Guthrie | SS | 22.195 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Luc Rennie | P | 24.070 | New York Mets | Columbia (A) | Assigned to Columbia (A) |
| Joe Cavallaro | P | 22.352 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Breckin Williams | P-IF | 24.303 | Arizona Diamondbacks | Kane County (A) | DL-7 Injured |
| Max Green | P | 22.038 | Detroit Tigers | West Michigan (A) | DL-7 Injured |
| Tyler Friis | 2B | 22.144 | Cleveland Indians | Lake County (A) | Activated from disabled list |
| Ryan Lawlor | P | 24.178 | Chicago Cubs | South Bend (A) | Assigned to South Bend (A) |
| Andrew Jordan | P | 20.336 | Cincinnati Reds | Daytona (A+) | Assigned to Daytona (A+) |
| Nick Margevicius | P | 22.017 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Tanner Kiest | P | 23.292 | - | | Released by Twins |
| Jason Delay | C | 23.120 | Pittsburgh Pirates | Bradenton (A+) | Activated from disabled list |
| Scott Squier | P | 25.291 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Will Latcham | P | 22.161 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Connor Johnstone | P | 23.274 | Atlanta Braves | Florida (A+) | Assigned to Florida (A+) |
| Jason Zgardowski | P | 24.281 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Herlis Rodriguez | OF | 24.025 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Tony Santillan | P | 21.081 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Erlin Cerda | 2B | 24.061 | Cleveland Indians | Lynchburg (A+) | DL-7 Injured |
| Alexis Pantoja | SS | 22.169 | Cleveland Indians | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Chris DeVito | C | 23.216 | - | | Released by Royals |
| Steve Berman | C | 23.219 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Activated from disabled list |
| Chris Paddack | P | 22.179 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Nolan Long | P | 24.167 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Gerardo Reyes | P | 25.053 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Michael Boyle | P | 24.084 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Dean Kremer | P | 22.180 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Juan Pena | P | 22.315 | Colorado Rockies | Lancaster (A+) | DL-7 Injured |
| Layne Somsen | P | 29.030 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Karch Kowalczyk | IF | 27.096 | Los Angeles Dodgers | Tulsa (AA) | Placed on temporarily inactive list |
| Michael Johnson | P | 27.183 | Los Angeles Dodgers | Tulsa (AA) | DL-7 Injured |
| Zachary Lovvorn | P | 24.040 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Jerry Keel | P | 24.282 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Elniery Garcia | P | 23.193 | St. Louis Cardinals | Springfield (AA) | Traded from Phillies to Cardinals for FC |
| Ryan McNeil | P | 24.154 | - | | Released by Cubs |
| Ryan Boldt | CF | 23.225 | Tampa Bay Rays | Montgomery (AA) | DL-7 Injured |
| Erick Castillo | C | 25.130 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| James Buckelew | P | 26.336 | Chicago Cubs | Tennessee (AA) | Signed to Minor League Contract |
| Brennan Bernardino | P | 26.172 | - | | Released by Reds |
| Emmanuel Marrero | IF | 25.050 | Philadelphia Phillies | Reading (AA) | Activated from disabled list |
| Sam Haggerty | IF | 24.040 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Josh Smith | P | 28.267 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Trevor Kelley | P | 24.258 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Matt Oberste | 1B | 26.331 | - | | Released by Mets |
| Aaron Brooks | P | 28.069 | Milwaukee Brewers | Colorado Springs (AAA) | Placed on temporarily inactive list |
| Eric Jokisch | P | 28.341 | Oakland Athletics | Nashville (AAA) | DL-7 Injured |
| Casey Coleman | P | 31.002 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Seth Simmons | P | 30.021 | San Diego Padres | El Paso (AAA) | DL-7 Injured |
| Todd Hankins | 3B-OF | 27.229 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Stephen Fife | P | 31.274 | Cleveland Indians | Columbus (AAA) | Activated from disabled list |
| Brady Dragmire | P | 25.150 | Washington Nationals | Syracuse (AAA) | DL-7 Injured |
| Chad Huffman | OF | 33.067 | Detroit Tigers | Toledo (AAA) | Placed on temporarily inactive list |
| Melky Cabrera | LF | 33.328 | Cleveland Indians | Columbus (AAA) | Signed to Minor League Contract |
| Zach Stewart | P | 31.280 | Toronto Blue Jays | Buffalo (AAA) | Signed to Minor League Contract |
| Brandon Cumpton | P | 29.231 | Toronto Blue Jays | Buffalo (AAA) | Signed to Minor League Contract |
| Donn Roach | P | 28.203 | - | | Released by White Sox |
| Enny Romero | RP | 27.162 | Kansas City Royals | Kansas City Royals (MLB) | Claimed off waivers from Pirates by Royals |
| Johnny Cueto | SP | 32.140 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Kelby Tomlinson | SS | 28.019 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| David Freitas | C | 29.109 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Chris Martin | RP | 32.033 | Texas Rangers | Texas Rangers (MLB) | DL-10 Left groin strain |
| Ricardo Rodriguez | P | 25.308 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Martin Prado | 3B | 34.252 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Ben Meyer | P | 25.156 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| J.B. Shuck | CF | 31.017 | Miami Marlins | Miami Marlins (MLB) | Designated for Assignment |
| Tayron Guerrero | RP | 27.177 | Miami Marlins | Miami Marlins (MLB) | DL-10 Left lumbar strain |
| Jefry Rodriguez | p | 24.344 | Washington Nationals | Washington Nationals (MLB) | Recalled from Syracuse (AAA) |
| Erick Fedde | P | 25.130 | Washington Nationals | Washington Nationals (MLB) | DL-10 Right shoulder inflammation |
| Francisco Cervelli | C | 32.121 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) for rehab |
| Cody Reed | RP | 25.081 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Dixon Machado | 2B | 26.134 | Detroit Tigers | Detroit Tigers (MLB) | Designated for Assignment |
| Victor Alcantara | RP | 25.093 | Detroit Tigers | Detroit Tigers (MLB) | Contract purchased from minors |
| Ronny Rodriguez | SS | 26.079 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Warwick Saupold | RP | 28.170 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Rob Zastryzny | RP | 26.101 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) for rehab |
| Kory Behenna | P | 21.337 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Tony Hernandez | P | 21.331 | - | | Announced retirement |
| Luis Hidalgo | 1B | 22.133 | - | | Released by Cubs |
| Tolly Filotei | OF | 22.220 | - | | Released by Cubs |
| Mauro Conde | OF | 21.034 | - | | Released by Reds |
| Jose Castillo | P | 22.025 | - | | Released by Reds |
| Francis Azcona | 2B | 22.228 | - | | Released by Reds |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Adam Parks | P | 25.268 | Texas Rangers | Frisco (AA) | Activated from disabled list |
| Elniery Garcia | P | 23.193 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Chris Reed | P | 28.046 | - | | Released by Marlins |
| James Buckelew | P | 26.336 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Ali Solis | C | 30.280 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Zach Stewart | P | 31.280 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Brandon Cumpton | P | 29.231 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Silvino Bracho | RP | 25.353 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Dalton Griffin | CF | 20.306 | - | | Announced retirement |
| Keury Mella | P | 24.337 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Devon Perez | P | 22.051 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Kiki Menendez | OF | 23.148 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Brandt Stallings | OF | 21.303 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Ismael Gomez | | 18.209 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Trevor Larnach | OF | 21.129 | Minnesota Twins | Elizabethton (Rk) | Signed out of draft (Oregon State University) |
| Orleny Quiroz | P | 24.349 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Eric De La Rosa | OF | 21.032 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Reece Hampton | OF | 21.351 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Chance Kirby | P | 22.352 | Detroit Tigers | Connecticut (A-) | Assigned to Connecticut (A-) |
| Tyler Joyner | P | 22.056 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Pablo O'Connor | 2B | 22.303 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Nick Gallagher | P | 22.300 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Ricardo Hernandez | P | 20.151 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Robert Broom | P | 21.291 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Eli Villalobos | P | 21.009 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Sherman Johnson | 3B | 27.355 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Injured |
| Carlos Perez | C | 27.251 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Nick Madrigal | SS | 21.122 | Chicago White Sox | Arizona White Sox (Rk) | Signed out of draft (Oregon State) |
| Zach Reeg | P | 22.238 | - | | Announced retirement |
| Luis Ubiera | OF | 21.291 | - | | Released by Cubs |
| Michael Grove | P | 21.199 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed out of draft (West Virginia University)
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