| Matt Koch | SP | 27.230 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Jake Barrett | RP | 26.334 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Kyle Farmer | IF | 27.307 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Chris Flexen | P | 23.354 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Hansel Robles | RP | 27.311 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Chris Tillman | SP | 30.066 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) for rehab |
| Pedro Alvarez | 1B | 31.134 | Baltimore Orioles | Norfolk (AAA) | Outrighted to minors |
| Corban Joseph | 2B | 29.235 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Andrew Cashner | SP | 31.282 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Adam Frazier | DH | 26.189 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Brady Rodgers | P | 27.276 | Houston Astros | Tri City (A-) | Assigned to Tri-City (A-) for rehab |
| Garrett Cooper | IF | 27.177 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) for rehab |
| Brock Stewart | SP | 26.261 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Joey Lucchesi | p | 25.014 | San Diego Padres | San Diego Padres (MLB) | Activated from DL |
| Bryan Mitchell | RP | 27.062 | San Diego Padres | San Diego Padres (MLB) | DL-10 Right elbow impingement |
| Brandon Morrow | RP | 33.329 | Chicago Cubs | Chicago Cubs (MLB) | DL-10 Lower back tightness |
| Mitchell Walding | SS | 25.283 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| J.P. Crawford | SS | 23.160 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-10 Broken left hand |
| Drew Verhagen | RP | 27.241 | Detroit Tigers | Detroit Tigers (MLB) | DL-10 Nasal fracture |
| John Barbato | RP | 25.344 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Juan Graterol | C | 29.126 | Los Angeles Angels | Salt Lake (AAA) | Designated for Assignment |
| Deck McGuire | P | 28.362 | Los Angeles Angels | Los Angeles Angels (MLB) | Traded from Rangers to Angels for PTBNL |
| Corey Dickerson | LF | 29.029 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Placed on Family Medical Emergency Leave |
| Aaron Whitefield | OF | 21.291 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Kyle Johnson | OF | 24.274 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Simon Muzziotti | OF | 19.175 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Tyler Viza | P | 23.242 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Greg Pickett | OF | 21.233 | Philadelphia Phillies | Gulf Coast Phillies West (Rk) | Assigned to Gulf Coast Phillies West (Rk) |
| Jeffrey Rosa | P | 23.015 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Ruben Alaniz | P | 27.006 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Yoiber Marquina | C | 22.138 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Nestor Oronel | P | 21.189 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Jose Cabello | C | 21.190 | - | | Released by Nationals |
| Max Schuemann | IF | 21.009 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Sam Wolff | P | 27.067 | San Francisco Giants | Arizona Giants Orange (Rk) | Assigned to Arizona Giants Orange (Rk) |
| Chris Heston | P | 30.071 | San Francisco Giants | Arizona Giants Orange (Rk) | Assigned to Arizona Giants Orange (Rk) |
| Chad Whitmer | P | 23.040 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Jose Bermudez | OF | 20.346 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Cameron Perkins | OF | 27.266 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| A.J. Franks | P | 22.361 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| J.C. Rodriguez | 2B | 22.160 | - | | Released by A's |
| Adrian Spitz | OF | 24.242 | - | | Released by A's |
| James Terrell | OF | 21.161 | - | | Released by A's |
| Alan Crowley | C | 22.108 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Cameron Baranek | CF | 23.120 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Tyler Watson | P | 25.011 | Atlanta Braves | Rome (A) | Signed to Minor League Contract |
| Dean Deetz | P | 24.203 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Eric Gutierrez | P | 24.174 | - | | Announced retirement |
| Kevin Marnon | P | 24.096 | Minnesota Twins | Fort Myers (A+) | DL-7 Injured |
| Colton Davis | P | 24.166 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| Brady Anderson | IF-P | 25.222 | Minnesota Twins | Fort Myers (A+) | Activated from disabled list |
| James Nelson | SS | 20.245 | Miami Marlins | Jupiter (A+) | Activated from disabled list |
| Ben Holmes | P | 26.282 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Reilly Hovis | P | 24.236 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Andrew Vasquez | P | 24.279 | Minnesota Twins | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Lukas Schiraldi | P | 24.330 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Zech Lemond | P | 25.254 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Marcus Crescentini | P | 25.176 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Brian Miller | IF-OF | 22.305 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Rob Kaminsky | P | 23.291 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Williams Ramirez | P | 25.316 | Minnesota Twins | Chattanooga (AA) | DL-7 Injured |
| Michael Peoples | P | 26.289 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Emmanuel Marrero | IF | 25.035 | Philadelphia Phillies | Reading (AA) | Activated from disabled list |
| Heiker Meneses | SS-2B | 26.355 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Jackson Williams | C | 32.037 | Pittsburgh Pirates | Indianapolis (AAA) | DL-7 Injured |
| Cesar Vargas | P | 26.173 | Washington Nationals | Syracuse (AAA) | DL-7 Injured |
| Ian Parmley | OF | 28.183 | Toronto Blue Jays | Buffalo (AAA) | Activated from disabled list |
| Mailon Arroyo | 3B | 20.169 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Assigned to Arizona Diamondbacks (Rk) |
| Zach Hoffpauir | OF | 24.272 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Eric Gutierrez | P | 24.174 | - | | Announced retirement |
| Eric Gutierrez | P | 24.174 | - | | Announced retirement |
| Eric Gutierrez | P | 24.174 | - | | Announced retirement |
| Aaron Ackerman | c | 21.050 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Signed out of draft (Illinois-Chicago) |
| Ryan Fitzpatrick | 1B | 23.099 | Chicago White Sox | Great Falls (Rk) | Assigned to Great Falls (Rk) |
| Jose Ramirez | P | 20.161 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Blake Workman | P | 20.255 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Marcelo Martinez | P | 21.314 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Colby Schultz | SS | 23.189 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Joe Ryan | P | 22.015 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Devin Foyle | OF | 21.214 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Tommy Wilson | P | 22.025 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Nick Meyer | C | 21.122 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Ryley Gilliam | P | 21.313 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| Chris Tillman | P | 30.066 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Josh McLain | OF | 21.270 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Devin Mann | IF | 21.129 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Jayson Werth | RF | 39.031 | - | | Announced retirement |
| Francisco Ruiz | C | 18.143 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| John Ham | IF-OF | 21.297 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Tanner Driskill | P | 22.154 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Alec Maley | P | 22.310 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Bobby Milacki | P | 21.226 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Jesse Wilkening | C | 21.295 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to Gulf Coast Phillies (Rk) |
| Jack Herman | OF | 18.264 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Cody Smith | P-UT | 22.282 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Jake Mielock | P | 23.162 | Pittsburgh Pirates | Gulf Coast Pirates (Rk) | Assigned to Gulf Coast Pirates (Rk) |
| Austin Hale | C | 22.238 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Jon Olsen | P | 21.038 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to Gulf Coast Twins (Rk) |
| Mitch Stallings | P | 22.356 | Atlanta Braves | Gulf Coast Braves (Rk) | Assigned to Gulf Coast Braves (Rk) |
| Austin Anderson | IF | 22.183 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Jon Rosoff | UT | 22.??? | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Jake Brodt | 1B | 22.149 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Griffin Conine | OF | 20.344 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Signed out of draft (Duke University) |
| Ethan DeCaster | P | 23.236 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Wes Noble | P | 22.024 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to Gulf Coast Tigers (East) (Rk) |
| Kris Bubic | P | 20.305 | Kansas City Royals | Arizona Royals (Rk) | Signed out of draft (Stanford University)
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