| Ryan Rua | 1B-LF | 28.097 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Elvis Andrus | SS | 29.294 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Eric Filia | OF | 25.345 | Seattle Mariners | Arkansas (AA) | Returned to Mariners after failing physical |
| Drew Hutchison | RP | 27.298 | Los Angeles Dodgers | Oklahoma City (AAA) | Signed to Minor League Contract |
| Melky Cabrera | RF-LF | 33.309 | Cleveland Indians | Columbus (AAA) | Outrighted to minors |
| Mike Foltynewicz | SP | 26.253 | Atlanta Braves | Atlanta Braves (MLB) | DL-10 Right triceps tendinitis |
| Luis Cessa | SP | 26.052 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) for rehab |
| Leury Garcia | CF | 27.090 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) for rehab |
| Steve Pearce | LF | 35.064 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) for rehab |
| Pierce Johnson | P | 27.037 | San Francisco Giants | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Brandon Belt | 1B | 30.057 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Shelby Miller | SP | 27.249 | Arizona Diamondbacks | Visalia (A+) | Assigned to Visalia (A+) for rehab |
| John Lamb | SP | 27.341 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| Oliver Drake | RP | 31.154 | Los Angeles Angels | Los Angeles Angels (MLB) | Designated for Assignment |
| Andrelton Simmons | SS | 28.285 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Nolan Fontana | IF | 27.010 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Mike Morin | RP | 27.044 | Seattle Mariners | Tacoma (AAA) | Outrighted to minors |
| D.J. Snelten | P | 26.018 | Baltimore Orioles | Norfolk (AAA) | Outrighted to minors |
| Jordan Zimmermann | SP | 32.024 | Detroit Tigers | Detroit Tigers (MLB) | Activated from DL |
| Artie Lewicki | P | 26.069 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Carlos Ramirez | OF | 27.053 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Connor Bennett | P | 21.067 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Reshard Munroe | OF | 22.001 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Aaron Quillen | P | 24.179 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Raul Wallace | OF | 22.302 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Miguel Aguilar | P | 22.327 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Adrian Chacon | C-1B | 23.100 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| J.D. Salmon-Williams | 2B | 21.087 | Cincinnati Reds | Dayton (A) | Assigned to Dayton (A) |
| Carlos Suniaga | P | 21.021 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Kenny Mendoza | P | 20.096 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Zack Draper | P | 23.241 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Paul Young | P | 25.093 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Humberto Castellanos | P | 20.074 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Jonathan Matute | 2B | 21.049 | - | | Released by Astros |
| Tre' Gantt | OF | 22.037 | Cleveland Indians | Mahoning Valley (A-) | Assigned to Mahoning Valley (A-) |
| Riley Echols | P | 23.065 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Cole Stobbe | SS | 20.290 | Philadelphia Phillies | Lakewood (A) | DL-7 Injured |
| Jhoan Quijada | P | 23.171 | Chicago White Sox | Kannapolis (A) | DL-7 Injured |
| Kevin Escorcia | P | 23.162 | Chicago White Sox | Kannapolis (A) | Activated from disabled list |
| Colby Fitch | C | 22.325 | Philadelphia Phillies | Lakewood (A) | Activated from disabled list |
| Andrew Jordan | P | 20.317 | Cincinnati Reds | Dayton (A) | Placed on temporarily inactive list |
| Dariel Aquino | DH | 22.138 | Houston Astros | Quad Cities (A) | Activated from disabled list |
| Andrew Summerville | P | 22.286 | St. Louis Cardinals | Peoria (A) | Placed on temporarily inactive list |
| Blayne Enlow | P | 19.087 | Minnesota Twins | Cedar Rapids (A) | Activated from disabled list |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Anthony Castro | P | 23.064 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Drew Carlton | P | 22.282 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Hunter Cervenka | P | 28.164 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Justin Kamplain | P | 25.123 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Austin Sexton | P | 23.334 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Trey Teakell | P | 26.120 | - | | Released by Tigers |
| C.J. Chatham | SS | 23.176 | Boston Red Sox | Salem (A+) | Activated from disabled list |
| Victor Diaz | P | 24.253 | Milwaukee Brewers | Carolina (A+) | Placed on temporarily inactive list |
| Conner Capel | OF | 21.028 | Cleveland Indians | Lynchburg (A+) | Activated from disabled list |
| Hunter Smith | P | 24.090 | Boston Red Sox | Salem (A+) | DL-7 Injured |
| Danny Dopico | P | 24.180 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Xavier Fernandez | C | 22.337 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| D.J. Myers | P | 23.174 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Blake Smith | P | 25.308 | Los Angeles Angels | Inland Empire (A+) | Activated from disabled list |
| Mac Marshall | P | 22.141 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Eric Filia | OF | 25.345 | Seattle Mariners | Arkansas (AA) | Assigned to Arkansas (AA) |
| Estarlin Arias | P | 24.025 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Matt Pearce | P | 24.112 | St. Louis Cardinals | Springfield (AA) | DL-7 Injured |
| Luis Mendez | 2B-3B | 25.166 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Michael Johnson | P | 27.164 | Los Angeles Dodgers | Tulsa (AA) | Assigned to Tulsa (AA) |
| Luis Villegas | C | 25.196 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Logan Taylor | IF | 24.267 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Jeffrey Springs | P | 25.269 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Yordan Alvarez | DH | 20.354 | Houston Astros | Corpus Christi (AA) | Activated from disabled list |
| Alec Hansen | P | 23.249 | Chicago White Sox | Birmingham (AA) | Activated from disabled list |
| Darren Seferina | 2B | 24.143 | Milwaukee Brewers | Biloxi (AA) | Activated from disabled list |
| Luis Pena | P | 22.297 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Peter Alonso | IF | 23.191 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Teddy Stankiewicz | P | 24.203 | Boston Red Sox | Portland (AA) | Placed on temporarily inactive list |
| Jeff McNeil | 2B | 26.069 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Joshua Torres | P | 24.051 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Joey Wong | SS-3B | 30.065 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Logan Darnell | P | 29.134 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| Andy LaRoche | 3B | 34.308 | Kansas City Royals | Omaha (AAA) | DL-7 Injured |
| Lindsey Caughel | P | 27.307 | Seattle Mariners | Tacoma (AAA) | Activated from disabled list |
| Nick Sergakis | 3B | 25.071 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Billy Burns | OF | 28.290 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Drew Hutchison | P | 27.298 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Chad Girodo | P | 27.130 | - | | Released by Dodgers |
| Colton Plaia | C | 27.264 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Tyler Eppler | P | 25.162 | Pittsburgh Pirates | Indianapolis (AAA) | Placed on temporarily inactive list |
| Brady Dragmire | P | 25.131 | Washington Nationals | Syracuse (AAA) | Placed on temporarily inactive list |
| Franklin Barreto | 2B | 22.110 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Josh Lucas | P | 27.223 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Nashville (AAA) |
| Matt Chapman | 3B | 25.049 | Oakland Athletics | Oakland Athletics (MLB) | DL-10 Right thumb contusion |
| Wendell Rijo | 2B | 22.286 | New York Yankees | Tampa (A+) | Traded from Brewers to Yankees |
| Boog Powell | OF | 25.153 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) for rehab |
| Ryan Buchter | RP | 31.123 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) for rehab |
| Matt Bowman | RP | 27.016 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Luke Voit | C | 27.123 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Jose Martinez | 1B | 29.326 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Placed on paternity leave list |
| Jung-Ho Kang | 3B | 31.072 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Luke Jackson | RP | 26.297 | | | Refused minor league assignment, declared free agent |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Zach Houchins | SS | 25.273 | Los Angeles Angels | Mobile (AA) | Activated from disabled list |
| Josh Turley | P | 27.294 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Josh Turley | P | 27.294 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Josh Turley | P | 27.294 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Josh Turley | P | 27.294 | - | | Announced retirement |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Andrew Summerville | P | 22.286 | St. Louis Cardinals | Peoria (A) | |
| Dace Kime | P | 26.102 | - | | Announced retirement |
| Carlos Perez | C | 27.232 | Texas Rangers | Texas Rangers (MLB) | DL-10 Right ankle sprain |
| Brandt Stallings | OF | 21.284 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Clayton Andrews | P | 21.163 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Luis Rosario | P | 21.128 | Texas Rangers | Spokane (A-) | Assigned to Spokane (A-) |
| Doug Still | P | 22.319 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Orleny Quiroz | P | 24.330 | San Francisco Giants | Salem-Keizer (A-) | Assigned to Salem-Keizer (A-) |
| Logan Gilbert | 1B-P | 21.042 | Seattle Mariners | Everett (A-) | Signed out of draft (Stetson) |
| Alex Holderbach | C | 21.172 | Houston Astros | Tri City (A-) | Reinstated to active roster |
| Michael Wielansky | SS | 21.090 | Houston Astros | Tri City (A-) | Reinstated to active roster |
| Travis Swaggerty | OF-P | 20.301 | Pittsburgh Pirates | West Virginia (A-) | Signed out of draft (South Alabama) |
| Riley Cabral | P | 21.142 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Devin Conn | IF-OF | 21.074 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Austin Hansen | P | 21.295 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Ariel Hernandez | P | 26.106 | Los Angeles Dodgers | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| C.J. McElroy | OF | 25.018 | Cincinnati Reds | Pensacola (AA) | DL-7 Injured |
| Boog Powell | OF | 25.153 | Oakland Athletics | Nashville (AAA) | Assigned to Nashville (AAA) |
| Luis Villegas | C | 25.196 | Kansas City Royals | Omaha (AAA) | DL-7 Injured |
| Ariel Miranda | P | 29.157 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
