| Andrew Susac | C | 28.072 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Brandon Belt | 1B-LF | 30.043 | San Francisco Giants | San Francisco Giants (MLB) | DL-10 Appendicitis |
| Gregor Blanco | LF | 34.173 | San Francisco Giants | San Francisco Giants (MLB) | Designated for Assignment |
| Ross Detwiler | RP | 32.088 | Seattle Mariners | Tacoma (AAA) | Signed to Minor League Contract |
| Hunter Pence | RF | 35.050 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Alen Hanson | 2B | 25.223 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Tyler Higgins | P | 27.041 | Seattle Mariners | Tacoma (AAA) | Signed to Minor League Contract |
| Nick Wittgren | RP | 27.004 | Miami Marlins | Miami Marlins (MLB) | DL-10 Right middle finger contusion |
| Tyler Cloyd | SP-RP | 31.017 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Daniel Reynolds | P | 27.031 | Milwaukee Brewers | Biloxi (AA) | Signed to Minor League Contract |
| Jorge De La Rosa | RP | 37.058 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-10 Right achilles tendon |
| Jake Barrett | RP | 26.316 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| P.J. Conlon | P | 24.203 | Los Angeles Dodgers | Oklahoma City (AAA) | Claimed off waivers from Mets by Dodgers and assigned to Oklahoma City (AAA) |
| Eliezer Alvarez | 2B-3B | 23.230 | Texas Rangers | Frisco (AA) | Outrighted to minors |
| Ricardo Pinto | P | 24.133 | Chicago White Sox | Winston-Salem (A+) | Outrighted to minors |
| Hanser Alberto | 3B | 25.228 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Carlos Tocci | of | 22.284 | Texas Rangers | Texas Rangers (MLB) | Activated from DL |
| Kole Calhoun | RF | 30.232 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-10 Right oblique strain |
| Michael Hermosillo | CF | 23.136 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Kaleb Cowart | 2B | 26.000 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Jaime Barria | SP | 21.319 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Jose Castillo | RP | 22.144 | San Diego Padres | San Diego Padres (MLB) | Recalled from El Paso (AAA) |
| Kyle Mcgrath | RP | 25.306 | San Diego Padres | El Paso (AAA) | Outrighted to minors |
| Andrew Lockett | P | 24.030 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Carlos Hernandez | P | 23.211 | New York Mets | Columbia (A) | Activated from disabled list |
| Conner O'Neil | P | 23.250 | New York Mets | Columbia (A) | DL-7 Injured |
| Danny Hrbek | P | 23.157 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Garrett Davila | P | 21.136 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Janser Lara | P | 21.296 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Isael Soto | OF | 21.212 | Miami Marlins | Greensboro (A) | Activated from disabled list |
| Bryan Sammons | P | 23.036 | Minnesota Twins | Cedar Rapids (A) | Activated from disabled list |
| Jayson McKinley | P | 24.135 | Arizona Diamondbacks | Kane County (A) | Assigned to Kane County (A) |
| Brian Shaffer | P | 21.294 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Ivan Pelaez | P | 24.121 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Rafael Pujols | P | 22.286 | Arizona Diamondbacks | Jackson (AA) | Assigned to Jackson (AA) |
| Nick Feight | C | 22.211 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Brusdar Graterol | P | 19.280 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Josh Roeder | P | 25.182 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Nick Ciuffo | C | 23.087 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) |
| Christian James | P | 20.009 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Keith Skinner | C | 24.049 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Kevin Marnon | P | 24.078 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Mitchell Tolman | IF | 23.359 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Anfernee Seymour | SS | 22.344 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Moises Gomez | P | 21.114 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Carlos Guzman | IF | 20.017 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Drew Crosby | P | 22.199 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Tyler Gaffney | RF-CF | 27.043 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Anthony Castro | P | 23.050 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Nick Fanti | P | 21.154 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Ryan Selmer | P | 24.013 | New York Mets | Kingsport (Rk) | Assigned to Kingsport (Rk) |
| Darren McCaughan | P | 22.076 | Seattle Mariners | Modesto (A+) | Assigned to Modesto (A+) |
| Aaron Cox | P | 23.301 | Los Angeles Angels | Inland Empire (A+) | DL-7 Injured |
| Marcus Greene | C | 23.287 | San Diego Padres | Lake Elsinore (A+) | Reinstated to active roster |
| Ramon Hernandez | 1B | 22.092 | Arizona Diamondbacks | Visalia (A+) | DL-7 Injured |
| Connor Overton | P | 24.313 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Matt Pearce | P | 24.098 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Andrew Aplin | OF | 27.073 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Chris Diaz | SS-2B | 27.205 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Daniel Reynolds | P | 27.031 | Milwaukee Brewers | Biloxi (AA) | Assigned to Biloxi (AA) |
| Mike Kickham | P | 29.172 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Taylor Ward | C | 24.170 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Kyle Barrett | OF | 24.302 | - | | Released by Marlins |
| Joel Payamps | P | 24.056 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Bruce Caldwell | 2B | 26.188 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Nick Tepesch | P | 29.233 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Reiver Sanmartin | P | 22.048 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Sam Hilliard | P | 24.101 | Colorado Rockies | Hartford (AA) | Activated from disabled list |
| Dillon Dobson | IF | 24.285 | San Francisco Giants | Richmond (AA) | DL-7 Injured |
| Tyler Bugner | OF | 23.216 | Colorado Rockies | Grand Junction (Rk) | Assigned to Grand Junction (Rk) |
| Zach Vincej | SS | 27.032 | Seattle Mariners | Tacoma (AAA) | DL-7 Injured |
| Destin Hood | OF | 28.060 | Texas Rangers | Round Rock (AAA) | Placed on temporarily inactive list |
| Joey Gunkel | P | 26.155 | Miami Marlins | New Orleans (AAA) | DL-7 Injured |
| Scott Van Slyke | 1B-LF | 31.313 | Miami Marlins | New Orleans (AAA) | Activated from disabled list |
| Javy Guerra | P | 32.214 | Miami Marlins | New Orleans (AAA) | Activated from disabled list |
| Ross Detwiler | P | 32.088 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Jansiel Rivera | CF | 19.278 | Seattle Mariners | Arizona Mariners (Rk) | Assigned to Arizona Mariners (Rk) |
| Tyler Higgins | P | 27.041 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Rosell Herrera | SS | 25.229 | Kansas City Royals | Omaha (AAA) | Claimed off waivers from Reds by Royals |
| Jacob Turner | P | 27.012 | - | | Released by Marlins |
| Matt Pobereyko | P | 26.161 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Brandon Snyder | 1B-3B | 31.191 | Tampa Bay Rays | Durham (AAA) | Activated from disabled list |
| Homer Bailey | SP | 32.030 | Cincinnati Reds | Cincinnati Reds (MLB) | DL-10 Right knee inflammation |
| Austin Brice | RP | 25.348 | Cincinnati Reds | Cincinnati Reds (MLB) | Activated from DL |
| Hyun-Jin Ryu | SP | 31.069 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Transferred to 60-day DL |
| Austin Maddox | C | 27.020 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) for rehab |
| Adam Lind | 1B-DH | 34.321 | Boston Red Sox | Pawtucket (AAA) | Signed to Minor League Contract |
| Nate Karns | SP | 30.190 | Kansas City Royals | Kansas City Royals (MLB) | Transferred to 60-day DL |
| Yadier Molina | C | 35.324 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) for rehab |
| Oliver Perez | P | 36.291 | Cleveland Indians | Cleveland Indians (MLB) | Signed to Minor League Contract |
| Jeff Beliveau | RP | 31.136 | Cleveland Indians | Cleveland Indians (MLB) | Designated for Assignment |
| Dustin Pedroia | 2B | 34.290 | Boston Red Sox | Boston Red Sox (MLB) | DL-10 Left knee inflammation |
| Bobby Poyner | p | 25.183 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Sam Travis | 3B | 24.279 | Boston Red Sox | Boston Red Sox (MLB) | Recalled from Pawtucket (AAA) |
| Gio Brusa | OF | 24.311 | San Francisco Giants | San Jose (A+) | Activated from disabled list |
| Adam Lind | 1B-DH | 34.321 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Garrett Boulware | C | 25.266 | - | | Announced retirement |
| Garrett Boulware | C | 25.266 | - | | Announced retirement |
| Cameron Rupp | C | 29.247 | | | Released by Rangers |
| Caleb Lopes | 2B | 22.317 | - | | Released by Cardinals |
| Austin Guibor | OF | 23.034 | - | | Released by Nationals |
| Joaquin De La Cruz | 3B | 22.233 | - | | Released by Brewers |
| Radhames Liz | P | 34.358 | - | | Released by Brewers |
| David Cronin | IF | 23.165 | - | | Released by White Sox |
| Logan Taylor | OF | 23.346 | - | | Released by White Sox |
| Jonathan Rivera | OF | 21.036 | - | | Released by Cardinals |
| Yeison Corredera | SS | 24.123 | - | | Released by Yankees |
| J.D. Murders | 2B | 20.239 | - | | Released by Cardinals |
| Jose Garcia | C-OF | 22.313 | - | | Released by White Sox |
| Alex Maloney | IF | 23.182 | - | | Released by White Sox |
| Lisandro Blanco | OF | 21.140 | - | | Released by Yankees |
| Reynier Montero | P | 21.216 | - | | Released by Rays |
| Jonathan Amundaray | OF | 20.022 | - | | Released by Yankees |
| Yerson Santana | OF | 21.182 | - | | Released by Rays |
| Malvin Del Orbe | C | 21.092 | - | | Released by Yankees |
| Jhon Moronta | OF | 19.016 | - | | Released by Yankees |
| Samuel De La Cruz | C | 20.227 | - | | Released by Yankees |
